Our research program is ranked third nationally among all urology departments for National Institutes of Health Funding. Our multidimensional, highly transformative approach aims to translate scientific discoveries into impactful medical solutions for patients.
Learn about the most recent research breakthroughs in the Department of Urology at Northwestern.
Areas of Research
Conducting research to help advance men’s health in the fields of male reproductive medicine, sexual medicine and surgery.
Analyzing the management and outcomes of patients born with congenital anomalies of the genitourinary system.
Evaluating robotic surgery techniques to improve patient outcomes and developing interventions to reduce kidney stone formation and recurrence.
Understanding racial health disparities in prostate cancer aggressiveness and outcomes, and improving urologic healthcare for sexual minorities.
Health Services and Outcomes Research
Studying care delivery and quality of care for urologic patients.
Infections, Inflammation and Pain
Developing new agents and interventions to improve outcomes and quality of life for patients with chronic pelvic pain and benign urologic conditions.
Creating the next generation of diagnostic and therapeutic nanoparticles.
Performing basic science and clinical research to improve the treatment and outcomes for children with urologic conditions.
Studying molecular, genetic and environmental contributors to prostate cancer to improve prostate cancer prevention, diagnosis and treatment.
Establishing new urologic tissue reconstruction models and developing treatment strategies for inflammation-based urologic conditions.
Developing novel surgical techniques for complex urologic reconstruction
Researching mechanisms of bladder and kidney cancer initiation and progression to develop novel therapeutics and treatments for genitourinary malignancies.
Clinical trials test or study drugs, surgical procedures, medical devices or interventions with human subjects. Read more about our actively recruiting clinical trials.
Policies & Resources
Our department wants to support our investigators in their efforts by making sure they’re updated on all of our policies for conducting responsible research and the many resources available to them.
Our residents spend a year working with Northwestern faculty to design and implement a basic science or clinical research project of their choice. See our Residency Curriculum section for more information on the role of research in our residency program.
Dr. Guo is working under mentor, Dr. Amy Krambeck, to design and lead a prospective randomized controlled trial involving a novel mobile health platform designed for chronic kidney stone formers to evaluate improvements in quality of life and quantitative measures of stone risk. The mobile application was designed in partnership with GetWell Loop and will feature interactive dietary and medication reminders, stone educational material, and secure messaging. In addition, she will be working on projects evaluating commercial lemonade beverage and effects on 24-hour urine collections and HoLEP outcomes in neurological disease states.
Dr. Li is working with Dr. Ashley Ross to understand the utility of digital pathology and artificial intelligence (AI) for prostate cancer risk stratification. His primary focus is using several AI algorithms to improve gleason grading, identification of variant histology, and prognostication for patients undergoing active surveillance and radical prostatectomy. Furthermore, he has an interest in understanding the interplay between prostate cancer histology, genomic alterations, and subtypes of prostate cancer which may predict response to systemic therapies. He will also be working on projects to integrate a prostate MRI nomogram into the Northwestern EMR, examine rates of genetic testing in patients with advanced prostate cancer, and characterize the use of relugolix within the Northwestern system.
Dr. Frydenlund is working with Dr. Meeks to better understand the molecular features of response to intravesical therapies in non-muscle invasive bladder cancer using digital spatial profiling. The goal of this research is to identify possible biomarkers to help predict response to BCG. Additionally, Dr. Frydenlund is evaluating the use of mesh strips in radical cystectomy to reduce the rate of parastomal hernia occurrence.