Dr. Podlasek earned her BS in Chemistry from Loyola University Chicago in 1987 and her PhD in Biochemistry from the University of Notre Dame in 1994.  Further training was received during a one-year postdoctoral fellowship at the University of Illinois, a three-year fellowship in the Department of Urology at Northwestern University's Feinberg School of Medicine, and three years as a Research Associate at Northwestern. Following her training, Dr. Podlasek spent three years as a Research Assistant Professor of Urology at Northwestern.  Dr. Podlasek is currently an Assistant Professor in the Department of Urology and conducts research into the molecular mechanisms which control normal penile development and dysregulation associated with erectile dysfunction.

Education

Undergraduate: Loyola University of Chicago, Chicago, IL
Graduate: PhD, Biochemistry, University of Notre Dame, Notre Dame, IN
Post-graduate: Molecular Genetics, Department of Ophthalmology, University of Illinois; Molecular Biology, Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL

Selected Publications
The following publications are selected from a complete CV. For more information on Dr. Podlasek's scholarly productivity, please contact her office.

Journal Articles

1. Carmichael I, Chipman DM, Podlasek CA, Serianni AS. Torsional effects on the one-bond 13C-13C spin coupling constant in ethylene glycol: insights into the behavior of 1JCC in carbohydrates. J Am Chem Soc. 115(23):10863-70. 1993.
2. Podlasek CA, Serianni AS. 19F and 13C NMR studies of polyol metabolism in freeze-tolerant pupae of Hyalophora cecropia. J Biol Chem. 269(4):2521-8. 1994.
3. Serianni AS, Podlasek CA. 13C-1H spin-coupling constants in carbohydrates: magnitude and sign determinations via 2D NMR methods. Carbohydr Res. 259(2):277-82. 1994.
4. Podlasek CA, Jian W, Stripe W, Bondo P, Serianni AS. [13C]enriched methyl aldopyranosides: structural interpretations of 13C-1H spin-coupling constants and 1H chemical shifts. J Am Chem Soc. 117(33):8635-44. 1995.
5. Podlasek CA, Stripe WA, Carmichael I, Shang M, Basu B, Serianni AS. 13C-1H spin-coupling constants in the beta-D-ribofuransoyl ring: effect of ring conformation on coupling magnitudes. J Am Chem Soc. 118(6):1413-25. 1996.
6. Podlasek CA, Duboule D, Bushman WA. Male accessory sex organ morphogenesis is altered by loss of function of Hoxd-13. Dev Dyn. 208(4):1-12. 1997.
7. Podlasek CA, Seo RM, Clemens JQ, Ma L, Maas RL, Bushman WA. Hoxa-10 deficient male mice exhibit abnormal development of the accessory sex organs. Dev Dyn. 214(1):1-12. 1999.
8. Podlasek CA, Clemens JQ, Bushman W. Hoxa-13 gene mutation results in abnormal seminal vesicle and prostate development. J Urol. 161(5):1655-61. 1999.
9. Podlasek CA, Barnett DH, Clemens JQ, Bak PM, Bushman W. Prostate development requires Sonic hedgehog expressed by the urogenital sinus epithelium. Dev Biol. 209(1):28-39. 1999.
10. Gonzalez CM, Bervig T, Podlasek C, Huang CF, McKenna KE, McVary KT. Sildenafil causes a dose- and time-dependent downregulation of phosphodiesterase type 6 expression in the rat retina. Int J Impot Res. 11(Suppl 1):S9-14. 1999.
11. Gonzalez CM, Brannigan RE, Bervig T, Zelner D, Podlasek CA, McKenna KE, McVary KT. Protein and gene expression of nitric oxide synthase isoforms I and III in the rat penile shaft. J Androl. 22(1):54-61. 2001.
12. Lamm ML, Podlasek CA, Barnett DH, Lee J, Clemens JQ, Hebner CM, Bushman W. Mesenchymal factor bone morphogenetic protein 4 restricts ductal budding and branching morphogenesis in the developing prostate. Dev Biol. 232(2):301-14. 2001.
13. Podlasek CA, Zelner D, Bervig TR, Gonzalez CM, McKenna KE, McVary KT. Characterization and localization of nitric oxide synthase isoforms in the BB/WOR diabetic rat. J Urol. 166(2):746-55. 2001.
14. Podlasek CA, Gonzalez CM, Zelner D, Jiang HB, McKenna KE, McVary KT. Analysis of NOS isoform changes in a post radical prostatectomy model of erectile dysfunction. Int J Impot Res. 13(Suppl 5):S1-15. 2001.
15. Podlasek CA, Houston J, McKenna KE, McVary KT. Posterior Hox gene expression in developing genitalia. Evol Dev. 4(2):1-22. 2002.
16. Podlasek CA, Zelner DJ, Jiang HB, Tang Y, Houston J, McKenna KE, McVary KT. Sonic hedgehog cascade is required for penile postnatal morphogenesis, differentiation, and adult homeostasis. Biol Reprod. 68(2):423-38. 2003.
17. Podlasek CA, Zelner DJ, Harris JD, Meroz CL, Tang Y, McKenna KE, McVary KT. Altered Sonic hedgehog signaling is associated with morphological abnormalities in the penis of the BB/WOR diabetic rat. Biol Reprod. 69(3):816-27. 2003.
18. Podlasek CA, Meroz CL, Korolis H, Tang Y, McKenna KE, McVary KT. Sonic hedgehog, the penis and erectile dysfunction: a review of Sonic hedgehog signaling in the penis. Curr Pharm Des. Submitted. 2004.

Contact Information

Northwestern University, Feinberg School of Medicine
Department of Urology
303 East Chicago Avenue, Tarry 16-703
Chicago, IL 60611-3008
(312) 503-7427
Fax (312) 908-7275
cap325@northwestern.edu

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Department of Urology
Northwestern University, Feinberg School of Medicine
303 East Chicago Avenue, Tarry 16-703
Chicago, IL 60611-3008
(312) 908-8145/ Fax (312) 908-7275 E-mail: m-grant@northwestern.edu