Neil Kelleher, PhD, Featured in Northwestern Medicine

Clara Peek, PhD, and Feng Yue, PhD, in Research Briefs

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The Kimberly Prize in Biochemistry and Molecular Genetics

Learn about our new annual prize

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Recent Faculty Promotions

See the latest Biochemistry & Molecular Genetics faculty members to be promoted

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R35 Grant Renewal

Congratulations to our faculty on renewal of their R35 grants

Our Mission

Epigenetic-driven insights are proving to be fundamental to a myriad of diseases including cancer, heart, immunologic and neurological conditions. The mission of the Simpson Querrey Institute for Epigenetics at Northwestern University Feinberg School of Medicine is the investigation of the link between environmental factors in the regulation of the expression of genes packaged within our chromatin. Such studies shall define how the misregulation of epigenetic processes can result in pathological conditions and how we can take advantage of such molecular information for developing treatments through targeted therapeutics.

We will work very hard to develop a deeper molecular understanding of the machinery involved in the regulation of epigenetics with an eye for developing targeted therapeutics for the treatment of diseases due to epigenetic abnormalities. These efforts, we expect, shall lead to more personalized medicine and a better quality of life."

– Ali Shilatifard, PhD, the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, Institute Director

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Research

The institute brings together experts in biochemistry, molecular genetics, computational biology, fundamental biology, epidemiology and clinical medicine to develop foundational insights about how environmental conditions – including emotional experiences, chemical exposure, obesity, exercise, diet and drug therapies – impact the human genome using sophisticated molecular, biochemical and computational methods.

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Featured Stories

SQE Membership

<p>Members of Northwestern University’s Simpson Querrey Center for Epigenetics (SQE) receive invitations to join faculty from both campuses in coming together to engage in collaborative discussions at regularly hosted seminars and events. Membership is open to all faculty, clinicians, students and staff.</p><p><a class="button" href="https://forms.feinberg.northwestern.edu/view.php?id=444276">Become a Member</a></p>

Members of Northwestern University’s Simpson Querrey Institute for Epigenetics (SQE) receive invitations to join faculty from both campuses in coming together to engage in collaborative discussions at regularly hosted seminars and events. Membership is open to all faculty, clinicians, students and staff.

Become a Member

Understanding Epigenetics

<p>Watch this original animation, which explains chromatin biology, epigenetics and the regulation of gene activity.</p><p><a class="button" href="https://youtu.be/XelGO582s4U">Watch Video</a></p>

Chromatin Biology

Watch this original animation, which explains chromatin biology, epigenetics and the regulation of gene activity.

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The Simpson Querrey Institute for Epigenetics

We study the effects of environment on the activation and expression of genes.

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About Our Name

Our work is supported by the generosity of University trustees and supporters Louis A. Simpson ’58 and Kimberly K. Querrey. For more than a decade, Simpson and Querrey have consistently supported Northwestern and made possible many strategic initiatives, including the Louis A. Simpson and Kimberly K. Querrey Biomedical Research Center, a 14-story, 600,000-square-foot building that significantly expanded Feinberg’s biomedical research enterprise.

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Our work is supported by the generosity of University trustees and supporters Louis A. Simpson ’58 and Kimberly K. Querrey. For more than a decade, Simpson and Querrey have consistently supported Northwestern and made possible many strategic initiatives, including the forthcoming <a href="https://www.feinberg.northwestern.edu/sites/simpson-querrey/">Louis A. Simpson and Kimberly K. Querrey Biomedical Research Center</a>, a 14-story, 600,000-square-foot building that will significantly expand Feinberg’s biomedical research enterprise.

Spotlights

Sephen Lander

Stephen Lander

G3 MD/PhD student recieves the NIH Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31-Diversity) grant. The title of the project is “Elucidating mechanisms of acetylcholine signaling in bacterial biofilms”. 

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Pblished in Nare Geneics

Published in Nature Genetics

Jindan Yu, MD/PhD, published in Nature Genetics for research on prostate cancer.

Marc Mendill, PhD

Marc Mendillo, PhD

American Cancer Society Research Scholar Grant recipient.

L Wang, PhD

Lu Wang, PhD

American Cancer Society Research Scholar Grant recipient.

Elizabeh McNally, MD/PhD

Elizabeth McNally, MD/PhD

Elected to the National Academy of Medicine.

Feng Ye, PhD

Feng Yue, PhD

Honored at investiture ceremony for endowed professorship.

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Nrhwesern Universiy Feinberg Schl f Medicine

Northwestern University Feinberg School of Medicine

Feinberg Rises to 15th in U.S. News Ranking for Research-Oriented Medical School

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