Coronavirus information for Feinberg.

Education & Seminars

Our members are active member of the Feinberg community, speaking at and participating in a number of educational events around campus on a variety of epigentics-related topics.

Use the tabs below to browse listings of upcoming genetics-related seminars and events. For a schedule of additional Northwestern University and Feinberg School of Medicine events, visit the Feinberg Medical School Event Calendar or PlanIt Purple.

Oct

22

Biochemistry, Epigenetics, and Metabolism (BEaM) Forum

Chicago - 1:00 PM - 2:00 PM

Presenters:

David Amici, PhD Student, Mendillo Lab, Biochemistry and Molecular Genetics

Julie Fischer, PhD Candidate, McNally Lab, Center for Genetic Medicine

The BEaM Forum is a data group where Simpson Querrey Institute for Epigenetics members present ongoing work being conducted. It is a great opportunity to get feedback on your work from colleagues, and to make new connections and foster new collaborations within the Institute.

Our forum will normally be held every other week from 1:00-2:00 p.m. Two presenters will give a 20-minute talk with 10 minutes for discussion and questions. We welcome presentation from students, techs, postdocs, and PIs. Presenting work-in-progress is always encouraged!

Refreshments will be provided.

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Nov

05

Biochemistry, Epigenetics, and Metabolism (BEaM) Forum

Chicago - 1:00 PM - 2:00 PM

Presenters:

Juan Wang, PhD Candidate, DGP Program, Bioinformatics

The BEaM Forum is a data group where Simpson Querrey Institute for Epigenetics members present ongoing work being conducted. It is a great opportunity to get feedback on your work from colleagues, and to make new connections and foster new collaborations within the Institute.

Our forum will normally be held every other week from 1:00-2:00 p.m. Two presenters will give a 20-minute talk with 10 minutes for discussion and questions. We welcome presentation from students, techs, postdocs, and PIs. Presenting work-in-progress is always encouraged!

Refreshments will be provided.

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Nov

19

Biochemistry, Epigenetics, and Metabolism (BEaM) Forum

Online - 1:00 PM - 2:00 PM

Presenter:

Elizabeth Bartom, Assistant Professor, Biochemistry and Molecular Genetics

The BEaM Forum is a data group where Simpson Querrey Institute for Epigenetics members present ongoing work being conducted. It is a great opportunity to get feedback on your work from colleagues, and to make new connections and foster new collaborations within the Institute.

Our forum will normally be held every other week from 1:00-2:00 p.m. Two presenters will give a 20-minute talk with 10 minutes for discussion and questions. We welcome presentation from students, techs, postdocs, and PIs. Presenting work-in-progress is always encouraged!

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Jan

14

Biochemistry, Epigenetics, and Metabolism (BEaM) Forum

Chicago - 1:00 PM - 2:00 PM

Presenters: TBD

The BEaM Forum is a data group where Simpson Querrey Institute for Epigenetics members present ongoing work being conducted. It is a great opportunity to get feedback on your work from colleagues, and to make new connections and foster new collaborations within the Institute.

Our forum will normally be held every other week from 1:00-2:00 p.m. Two presenters will give a 20-minute talk with 10 minutes for discussion and questions. We welcome presentation from students, techs, postdocs, and PIs. Presenting work-in-progress is always encouraged!

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Oct

21

Biochemistry and Molecular Genetics Departmental Seminar Series: Grant D. Barish, MD, Northwestern University

Chicago - 10:00 AM - 11:00 AM

The Department of Biochemistry and Molecular Genetics presents:

Grant D. Barish, MD, Associate Professor, Endocrinology, Northwestern University

Title: Translational control of skeletal muscle mass by the transcriptional repressor BCL6

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Oct

28

Biochemistry and Molecular Genetics Departmental Seminar Series: Jon Coloff, PhD, UIC

Chicago - 10:00 AM - 11:00 AM

The Department of Biochemistry and Molecular Genetics presents:

Jon Colloff, Assistant Professor, Physiology & Biophysics, University of Illinois, Chicago

Title: "Targeting Serine Auxotrophy in Luminal Breast Cancer"

Abstract:

A major challenge of targeting metabolism for cancer therapy is pathway redundancy, where multiple sources of critical nutrients can diminish the effects of metabolic therapies. An example of this can be found in recent attempts to target the serine synthesis pathway for cancer therapy, where the abundance of serine available to be taken up from the circulation has hampered the success of inhibitors of serine biosynthesis. This places a premium on pursuing strategies of limiting pathway redundancy if we wish to successfully target serine and other critical metabolic pathways for cancer therapy. We have taken the approach of analyzing human tumor gene expression data to identify scenarios where pathway redundancy is limited due to lineage-dependent gene expression, thereby creating potential vulnerabilities. Using this approach, we have found that the two major lineages of breast tumors luminal and basal express vastly different levels of PSAT1 (phosphoserine aminotransferase 1), the gene encoding the second enzyme of the serine synthesis pathway. Luminal breast cancer cells, which express extremely low levels of PSAT1, are unable to activate the serine synthesis pathway even when extracellular serine is completely absent. As a result, they are entirely dependent on exogenous serine for proliferation and survival and are sensitive to dietary serine and glycine starvation. This is in contrast to basal breast cancer cells, which are able to synthesize serine and proliferate in the absence of extracellular serine. Mechanistically, this serine auxotrophy is due to lineage-specific methylation of the PSAT1 gene in luminal breast tumors. Interestingly, the PSAT1 methylation and expression phenotypes observed in human breast tumors pre-exist in the cells-of-origin for these tumors in the normal mammary gland, emphasizing the importance of cell lineage in dictating this phenotype. Ongoing work in the Coloff Lab is continuing to characterize serine auxotrophy as a potentially targetable vulnerability of luminal breast tumors.

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Oct

29

BMG Departmental Journal Club

Chicago - 1:00 PM - 2:00 PM

Presenter:

Bercin Cenik, Postdoctoral Scholar, Shilatifard Lab, Biochemistry and Molecular Genetics

Milad Alasady, Postdoctoral Scholar, Mendillo Lab, Biochemistry and Molecular Genetics

The BMG Journal Club is an opportunity for the department to come together and have in-depth discussions about the current literature and the overall implications of new studies, enhancing everyone s knowledge of the field at large and about each other s research interests within the department; providing possible opportunities to collaborate as well. This is also an opportunity to practice vital presentation skills in front of a friendly audience.

Refreshments will be provided.

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Nov

04

Biochemistry and Molecular Genetics Departmental Seminar Series: Alex Ruthenberg, PhD, UIC

Chicago - 10:00 AM - 11:00 AM

The Department of Biochemistry and Molecular Genetics presents:

Alex Ruthenberg, Associate Professor, Cell and Molecular Biology

University of Illinois, Chicago

Title: "Bivalency and its Discontents: Subjecting the Dogma to Quantitative Analysis"

Abstract:

Nucleosomes, composed of DNA and histone proteins, represent the fundamental repeating unit of the eukaryotic genome; posttranslational modifications of these histone proteins are thought to influence the activity of the associated genomic regions to regulate cell identity. Traditionally, trimethylation of histone H3K4 (H3K4me3) is associated with transcriptional initiation, whereas trimethylation of H3K27 (H3K27me3) is considered transcriptionally repressive. The apparent juxtaposition of these opposing marks, termed bivalent domains , was proposed to specifically demarcate of small set transcriptionally-poised lineage-commitment genes that resolve to one constituent modification through differentiation, thereby determining transcriptional status. Since then, many thousands of studies have canonized the bivalency model as a chromatin hallmark of development in many cell types. However, these conclusions are largely based on chromatin immunoprecipitations (ChIP) with significant methodological problems hampering their interpretation. Absent direct quantitative measurements, it has been difficult to evaluate the strength of the bivalency model. Here, we present reICeChIP, a calibrated sequential ChIP method to quantitatively measure nucleosomes with H3K4me3 and H3K27me3 genome-wide, addressing the limitations of prior measurements. With reICeChIP, we profile bivalency through the differentiation paradigm that first established this model: from na ve mouse embryonic stem cells (mESCs) into neuronal progenitor cells (NPCs). Our results cast doubt on every aspect of the bivalency model; in this context, we find that bivalency is widespread rather than restricted to early developmental genes, bivalency does not resolve with differentiation, but increases instead, and is neither sensitive nor specific for identifying poised developmental genes or gene expression status more broadly. Our findings caution against imbuing bivalent domains as meaningful markers of developmentally poised genes.

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Nov

10

Biochemistry and Molecular Genetics Departmental Seminar Series: Kenneth Zaret, PhD, University of Pennsylvania

Chicago - 10:00 AM - 11:00 AM

The Department of Biochemistry and Molecular Genetics presents:

Kenneth Zaret, Joseph Ledy Professor, Department of Cell and Developmental Biology

University of Pennsylvania

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Nov

10

Biochemistry and Molecular Genetics Departmental Seminar Series: Kenneth Zaret, PhD, University of Pennsylvania [copy]

Chicago - 10:00 AM - 11:00 AM

The Department of Biochemistry and Molecular Genetics presents:

Kenneth Zaret, Joseph Ledy Professor, Department of Cell and Developmental Biology

University of Pennsylvania

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Nov

12

BMG Departmental Journal Club

Chicago - 1:00 PM - 2:00 PM

Presenters:

Marc Morgan, Research Assistant Professor, Shilatifard Lab, Biochemistry and Molecular Genetics

Alex Lee, Graduate Student, Foltz Lab, Biochemisty and Molecular Genetics

The BMG Journal Club is an opportunity for the department to come together and have in-depth discussions about the current literature and the overall implications of new studies, enhancing everyone s knowledge of the field at large and about each other s research interests within the department; providing possible opportunities to collaborate as well. This is also an opportunity to practice vital presentation skills in front of a friendly audience.

Refreshments will be provided.

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Dec

02

Biochemistry and Molecular Genetics Departmental Seminar Series: Keara Lane, PhD, Northwestern University

Chicago - 10:00 AM - 11:00 AM

The Department of Biochemistry and Molecular Genetics presents:

Keara Lane, Assistant Professor, Molecular Biosciences, Northwestern University

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Dec

03

BMG Departmental Journal Club

Chicago - 1:00 PM - 2:00 PM

Presenters:

Yohhei Takahashi, Research Assistant Professor, Shilatifard Lab, Biochemistry and Molecular Genetics

Huijue Lyu, Graduate Student, Yue Lab, Biochemistry and Molecular Genetics

The BMG Journal Club is an opportunity for the department to come together and have in-depth discussions about the current literature and the overall implications of new studies, enhancing everyone s knowledge of the field at large and about each other s research interests within the department; providing possible opportunities to collaborate as well. This is also an opportunity to practice vital presentation skills in front of a friendly audience.

Refreshments will be provided.

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Oct

21

Immunology Journal Club

Chicago - 12:00 PM - 1:00 PM

Immunology topics presented

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Oct

22

CDB Special Seminar: Peter Maddox, Ph.D., University of North Carolina at Chapel Hill

Off-Campus - 12:00 PM - 1:00 PM

CDB SPECIAL SEMINAR:

"New methods for LITE imaging of microtubule dynamics in the mitotic spindle reveal unsuspected behaviors"

Paul S. Maddox, Ph.D.

Associate Professor and William Burwell Harrison Scholar
Department of Biology
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina

Friday, October 22, 2021

12:00-1:00 PM

Hybrid Seminar

Location: David Hale Williams Auditorium, McGaw 2-320

Zoom Link: https://northwestern.zoom.us/j/95584864355

Meeting ID: 955 8486 4355

Password: Available upon request from cdb@northwestern.edu

Dial in Number: +1 312 626 6799 US

Abstract:

The mitotic spindle segregates the duplicated genome every cell cycle. Microtubules in the spindle bind to the kinetochore region of chromosomes and generate the force required for segregation. Microtubules are intrinsically dynamic, those bound to kinetochores exhibit suppressed dynamics and have the unusual trait of poleward microtubule flux wherein the plus ends continuously polymerize at kinetochores while the corresponding minus ends depolymerize at the spindle pole. We have developed a new single molecule imaging method for measuring poleward microtubule flux and reveal unexpected microtubule dynamics relative to kinetochores. We have modified the LITE imaging technique we pioneered several years age to remove chromatic aberration and increase power in the illumination path while maintaining limited photobleaching. The result is a light sheet capable of single molecule imaging (for SMLM super resolution and/or live cell imaging) for long periods of time. This technology opens new possibilities for live single molecule tracking of cellular events.

Hosts:

Dr. Volodya Gelfand, Professor
Department of Cell and Developmental Biology

and

Dr. Constadina Arvanitis, Research Associate Professor
Department of Cell and Developmental Biology
Director of the Center for Advanced Microscopy & Nikon Imaging Center

For more information please contact cdb@northwestern.edu
Zoom link sent via listserv. To subcribe to the CDB Seminar Series listserv please visit https://www.feinberg.northwestern.edu/sites/cdb/about/contact.html#listserv

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Oct

22

"Learning to aggress – Behavioral and circuit mechanisms of aggression reward"

Online - 12:00 PM - 1:00 PM

The Department of Neuroscience welcomes Dr. Sam A. Golden, Assistant Professor, with the University of Washington to the 2021/2022 seminar series.

Abstract

Aggression is an ethologically complex behavior with equally complex underlying mechanisms. Here, I present data on one form of aggression, appetitive or rewarding aggression, and the behavioral, cellular and system-level mechanisms guiding this behavior. First, I will present one way in which appetative aggression is modeled in mice, and extend aggression motivation to the concept of compulsive aggression seeking and relapse. I will then briefly highlight recent advances in computer vision and machine learning for automated scoring of aggressive behavior, the role of specific cell-types in controlling aggression reward, and close with preliminary data on the whole brain aggression reward functional connectome using light sheet fluorescent microscopy

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Oct

22

TEAM/SBDRC Seminar: Lectures by Irina Budunova, MD, PhD and Melissa Brown, PhD - REDD1 as Predictor of Response to Glucocorticoids and Regulator of Immune Response

No Location - 12:00 PM - 1:00 PM

The Robert H. Lurie Comprehensive Cancer Center of Northwestern University's Tumor Environment and Metastasis Program and the Skin Biology and Diseases Resource-Based Center present:

Can Early Stress-Response Gene REDD1 Dissociate Therapeutic and Adverse Effects of Glucocorticoids?

Irina Budunova, MD, PhD
Professor
Dermatology and Urology
Northwestern University
Feinberg School of Medicine

REDD1: A Potent Regulator of Adaptive and Innate Immune Responses

Melissa Brown, PhD
Professor
Microbiology-Immunology
Northwestern University
Feinberg School of Medicine

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Oct

25

"Synthetic biology approaches to retune gene regulation at the RNA level" - Bryan C. Dickinson, Ph.D.

Online - 4:00 PM - 5:00 PM

Bryan C. Dickinson, Ph.D.
Associate Professor of Chemistry
University of Chicago

Abstract: RNA transcribed from the genome in the nucleus bears little resemblance to the RNA polymer it will ultimately become in the cytoplasm where it is translated into protein. Well-known processes such as capping, splicing and polyadenylation, as well as the recently discovered and ever-expanding list of diverse chemical modifications and editing, significantly alter the properties and fates of a given RNA during the course of its lifetime. These alterations regulate critical aspects of RNA function such as stability, transport, protein binding, and translation. Especially in mammalian systems, these post-transcriptional gene expression regulatory processes are often a key determinant of genetic information flow. Moreover, from an engineering and therapeutic perspective these RNA regulatory processes represent new ways to control or retune gene expression at the RNA level, if they can be harnessed. I will present technologies our group has developed to control protein-RNA interactions with an eye toward therapeutic development.

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Oct

26

Lurie Cancer Center Basic Research Seminar: Not All T Cell Responses are Created Equal

Online - 11:00 AM - 12:00 PM

The Lurie Cancer Center Basic Research Seminar Series and the Signal Transduction and Cancer Training Program (T32 CA070085) present:

Not All T Cell Responses are Created Equal

Stefani Spranger, PhD
Howard S, and Linda B. Stern
Career Development Professor Koch Institute for Integrative
Assistant Professor of Biology, MIT

Tuesday, October 26, 2021
11:00 a.m. - 12:00 p.m.

Cancer immunotherapies have revolutionized cancer treatment, but only a fraction of patients respond. The presence of CD8 cytolytic, "killer" T cells within the tumor microenvironment is a key factor in response to checkpoint blockade therapy. This talk will highlight factors that contribute to T cell exclusion from the tumor microenvironment, including tumor cell-intrinsic, tissue-macroenvironmental or environmental factors (e.g. infections). The Spranger lab studies lung and pancreatic cancer as respective models of immunotherapy sensitive and resistant cancer types.

All members of the Northwestern Medicine community are invited to attend.

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Oct

26

M-I Dept. Seminar Series - "Using the Microbiology and Chemistry of the Built Environment to Promote Indoor Environmental Quality"

Chicago - 12:00 PM - 1:00 PM

Title: Using the Microbiology and Chemistry of the Built Environment to Promote Indoor Environmental Quality

Erica Hartmann, PhD

Assistant Professor of Civil and Environmental Engineering

Faculty Host: Alan Hauser, MD, PhD

Topic:

The built indoor environment is enriched for antibiotic-resistant pathogens compared to natural outdoor environments. Using molecular and traditional microbiology techniques, my research assesses whether synthetic antimicrobial chemicals, often included in cleaning or building products, are indeed associated with decreased microbial viability. Using simplified microbial communities and microcosm experiments, we probe causal relationships between exposure to antimicrobial chemicals and the development of different resistance phenotypes and genotypes. Based on these findings, we are assessing new, bio-inspired approaches to controlling microbial communities.

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Oct

27

Bacteriology Journal Club

Chicago - 12:00 PM - 1:00 PM

Bacteriology article presentation or research in progress from graduate students and post docs.

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Oct

27

CDB Trainee Seminars Presents: Myung-Su Kang, PhD and Hannah Sunshine

Online - 12:00 PM - 1:00 PM

CDB Trainee Seminars Presents:

"Autism-like behavior caused by the disruption of the autophagic Beclin 1"

Myung-Su Kang, PhD, Postdoctoral Fellow, He Lab
12:00-12:30 PM

"ZFP36 mediated regulation of endothelial activation for neovascularization"

Hannah Sunshine, Graduate Student, Arispe Lab
12:30-1:00 PM

Zoom link sent via listserv. To subcribe to the CDB Seminar Series listserve please visit https://www.feinberg.northwestern.edu/sites/cdb/about/contact.html#listserv

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Oct

27

DAAD RISE Workshop

No Location - 12:00 PM - 1:00 PM

The DAAD Research Internship in Science and Engineering offers funded summer research internships at top German universities and research institutions! Open to students in STEM and Engineering fields. Current Sophomores and Juniors are eligible. Students apply to 3 opportunities that best match their area of interest. German language ability desirable, but not required. Register here: https://northwestern.zoom.us/j/91988238559

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Oct

27

Cancer Connections

Online - 5:45 PM - 7:30 PM

At the Lurie Cancer Center, your treatment plan includes care for the mind, body and spirit. Cancer Connections is just what the doctor ordered, introducing tools, techniques and services you can use to reenergize during and after treatment. Patients and caregivers are invited to attend our virtual programs and learn from cancer experts and find local and national support resources available to both patients and caregivers.

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Oct

28

Immunology Journal Club

Chicago - 12:00 PM - 1:00 PM

Immunology topics presented

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Nov

01

Germany Alumni Panel

Evanston - 4:30 PM - 5:30 PM

Listen to a panel of Wildcats who spent time in Germany discuss their experiences! Germany offers multiple ways to study, research, and engage. On this panel, hear the expereinces of people who have won fellowships and completed study abroad! Open to students in all fields. German language ability desirable, but not required. Bring your interest to explore and learn outside the US!

*** This event will take place both in person and online. To attend in person, go to Kresge 1-515. You need not register to attend in person. To attend online, register here: https://northwestern.zoom.us/j/98113327328

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Nov

02

Translational Research in Solid Tumors (TRIST) Seminar: Precision Nanotherapeutics for Treatment of Glioblastoma

Chicago - 11:00 AM - 12:00 PM

The Translational Research in Solid Tumors (TRIST) Program presents:

Precision Nanotherapeutics for Treatment of Glioblastoma

Alexander H. Stegh, PhD
Associate Professor of Neurology (Neuro-oncology) and Medicine
The Ken & Ruth Davee Department of Neurology
Feinberg School of Medicine

The
Stegh lab, in collaboration with Dr Chad Mirkin, developed a novel
precision medicine approach for glioblastoma ( treatment involving
brain penetrant spherical nucleic acids ( conjugated with gene
regulatory siRNA or immunostimulatory DNA oligonucleotides SNAs are
modular nanostructures, composed of densely functionalized and highly
oriented nucleic acids that are spherically presented around a nanoparticle
core This unique 3 D architecture leads to biochemical and biological
properties that are radically different from linear oligonucleotides,
including delivery and privileged access to intracranial tumor sites upon
systemic administration Dr Stegh will review preclinical data that establish
SNAs as a potent gene regulatory platform that, upon IV administration,
downregulates oncogene expression in intracranial GBM Results from a
single arm, open label phase 0 first in human trial NCT 03020017 to
determine safety, pharmacokinetics, intratumoral accumulation and gene
suppressive activity of SNAs with gold nanoparticle cores, carrying siRNA
specific for the GBM oncogene Bcl 2 Like 12 will be presented The
presentation will conclude with an outlook on development of novel
immuno stimulatory SNA based therapies, including SNA architectures that
activate cGAS STING innate immunity.

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Nov

02

M-I Dept. Seminar Series - "Phenotypic Heterogeneity in Clostridioides difficile"

Chicago - 12:00 PM - 1:00 PM

Title: Phenotypic Heterogeneity in Clostridioides difficile

Rita Tamayo, PhD

Associate Professor, Dept. of Microbiology and Immunology, University of North Carolina School of Medicine

Faculty Host: Hank Seifert

Topic:

Clostridioides difficile causes antibiotic-associated disease ranging from mild diarrhea to potentially fatal pseudomembranous colitis, and it is one of the most common causes of nosocomial infections in the U.S. Recent work from our lab and others has shown that C. difficile generates extensive phenotypic heterogeneity through the process of phase variation. This talk will present some of our latest work uncovering the mechanisms and consequences of phase variation in C. difficile physiology and virulence, highlighting the ways in which this process in C. difficile differs from systems described in other bacteria.

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Nov

02

Truman Scholarship Information Session

Online - 12:00 PM - 1:00 PM

The Harry S. Truman Scholarship Foundation supports the graduate education and professional development of outstanding young people committed to public service leadership.

Learn more about the Truman Scholarship and application process by registering for this information session, offered by the Northwestern Office of Fellowships. Please register using your Northwestern email address. Register here.

Find helpful Truman Scholarship documents on the Office of Fellowships Info Sessions website here.

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Nov

03

Bacteriology Journal Club

Chicago - 12:00 PM - 1:00 PM

Bacteriology article presentation or research in progress from graduate students and post docs.

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Nov

03

Department Faculty Meeting

No Location - 12:00 PM - 1:00 PM

Cell & Developmental Biology Department Faculty Meeting

Meeting details disseminated via listserv. If you believe you missed an announcement, please email us at cdb@northwestern.edu.

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Nov

04

CDB Trainee Meeting: Talk Mechanics

No Location - 12:00 PM - 1:00 PM

CDB Trainee Meeting: Talk Mechanics

This session is part of CDB's quarterly Trainee Seminar Series training meetings

Please join us for a discussion of best practices when preparing and giving effective presentations, focusing specifically on the mechanics that make a "good" talk.

Thursday, November 4, 2021

12:00-1:00pm

Location TBA

Meeting details will be shared via listserv. Please contact cdb@northwestern.edu for more information.

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Nov

04

Immunology Journal Club

Chicago - 12:00 PM - 1:00 PM

Immunology topics presented

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Nov

05

Cancer Survivorship Symposium

Online - 8:30 AM - 3:00 PM

On Friday, November 5, the virtual Cancer Survivorship Symposium will bring together researchers, clinicians and other healthcare professionals interested in improving outcomes for cancer survivors and implementing best practice models to optimize patient outcomes. Participants will hear presentations and engage in discussions focused on supporting evidence-based, equitable cancer survivorship care.

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Nov

09

M-I Dept. Seminar Series - “Decrypting Microbiologic Aspects of Periprosthetic Joint Infection”

Chicago - 12:00 PM - 1:00 PM

Title: Decrypting Microbiologic Aspects of Periprosthetic Joint Infection

Robin Patel, MD, Mayo Clinic

Director, Infectious Diseases Research Laboratory, and Chair, Division of Clinical Microbiology

Faculty Host: Karla Satchel, PhD

Topic:

Periprosthetic joint infection is a biofilm-associated infection caused by a multitude of bacterial species. In this presentation, the epidemiology, microbiology, and pathogenesis of periprosthetic joint infection will be presented. Insight into pathogenesis of arthroplasty failure provided by metagenomic shotgun whole genome sequencing will be shared.

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Nov

10

Bacteriology Journal Club

Chicago - 12:00 PM - 1:00 PM

Bacteriology article presentation or research in progress from graduate students and post docs.

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Nov

10

CDB Seminar Series Presents: "Chromosome dynamics during the cell cycle," Daniel Gerlich, PhD, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna, Austria

Online - 12:00 PM - 1:00 PM

CDB EXPERTS-IN-THE-FIELD SEMINAR PRESENTATION:

"Chromosome dynamics during the cell cycle"

Daniel Gerlich, PhD
Senior Research Group Leader
Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA),
Vienna, Austria

Wednesday, November 10, 2021

12:00-1:00 PM

Zoom Link: https://northwestern.zoom.us/j/94371859347

Meeting ID: 943 7185 9347

Password: Available upon request from cdb@northwestern.edu

Dial in Number: +1 312 626 6799 US
+43 72 011 5988 Austria

Relevant Publications:

S. Cuylen-Haering, M. Petrovic, A. Hernandez-Armendariz, M.W. G. Schneider, M. Samwer, C. Blaukopf, L.J. Holt, D.W. Gerlich. Chromosome clustering by Ki-67 excludes cytoplasm during nuclear assembly. Nature (2020). 587(7833): 285-290. doi: 10.1038/s41586-020-2672-3.

M. Mitter, C. Gasser, Z. Takacs, C. C. H. Langer, W. Tang, G. Jessberger, C. T. Beales, E. Neuner, S. L. Ameres, J.-M. Peters, A. Goloborodko, R. Micura, Daniel W. Gerlich. Conformation of sister chromatids in the replicated human genome. Nature (2020). 586(7827): 139-144. doi: 10.1038/s41586-020-2744-4.

P. Batty, D.W. Gerlich. Mitotic Chromosome Mechanics: How Cells Segregate Their Genome. Trends Cell Biol (2019). 29(9): 717-726. doi: 10.1016/j.tcb.2019.05.007.

Host: Dr. Dileep Varma, Assistant Professor
Department of Cell and Developmental Biology

For more information please contact cdb@northwestern.edu
Zoom link sent via listserv. To subcribe to the CDB Seminar Series listserve please visit https://www.feinberg.northwestern.edu/sites/cdb/about/contact.html#listserv

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Nov

11

Immunology Journal Club

Chicago - 12:00 PM - 1:00 PM

Immunology topics presented

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Nov

11

Symposium in honor of Dr. Jonathan Leis on his transition to Emeritus

Online - 12:00 PM - 2:00 PM

Please join us for a symposium honoring Jonathan P. Leis, PhD, professor of Microbiology-Immunology and former executive associate dean for research at Northwestern University Feinberg School of Medicine.

Schedule:

Noon - 12:05 p.m. CT Welcome
Laimonis Laimins, PhD
Guy and Anne Youmans Professor and Chair of Microbiology-Immunology
Northwestern University Feinberg School of Medicine

12:05 - 12:40 p.m. CT My career-long fascination with antiviral therapeutics
Craig Cameron, PhD
Professor and Chair of Microbiology and Immunology
University of North Carolina School of Medicine

12:45 - 1:20 p.m. CT Co-Transcriptional Recognition of Functional Splice Sites in Mammalian Genomes
Xiang-Dong Fu, PhD
Distinguished Professor of Cellular and Molecular Medicine
University of California, San Diego

1:25 - 2 p.m. CT The winding road from poxvirus host range factors to novel myeloid tumor suppressors
Yan Xiang, PhD
Professor of Microbiology and Immunology & Molecular Genetics
UT Health San Antonio

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Nov

11

DAAD RISE Workshop

Evanston - 4:00 PM - 5:00 PM

The DAAD Research Internship in Science and Engineering offers funded summer research internships at top German universities and research institutions! Open to students in STEM and Engineering fields. Current Sophomores and Juniors are eligible. Students apply to 3 opportunities that best match their area of interest. German language ability desirable, but not required.

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Nov

12

5th Annual Translational Bridge Symposium

Chicago - 9:00 AM - 12:30 PM

The Robert H. Lurie Comprehensive Cancer Center of Northwestern University is committed to fostering collaborations between physicians and basic scientists to advance translational cancer research with the ultimate goal of translating basic science discoveries to the clinic and impacting cancer patient outcomes. Designed to stimulate collaboration between basic scientists, population scientists, and translational clinical investigators, this symposium will feature brief presentations by scientists and clinical investigators on research discoveries with potential for clinical trial development.

This meeting is currently scheduled to be in person with a Zoom option for remove viewing. Updates will be provided to registrants in November. Registration is complimentary, but advance registration is required.

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Nov

12

Writing Your Teaching Statement: Peer Review

Online - 10:00 AM - 12:00 PM

Teaching statements are an important component of many academic job applications, but they can be challenging to write. Receiving feedback from peers can provide you with recommendations on how to clarify and improve your main claims about your teaching. Allowing others to read your writing can also give you critical insight into how your target audience may understand and interpret your claims, which can help further refine your teaching statement.

In this workshop, participants will share their teaching statement drafts and engage in guided peer feedback.

This workshop is open to graduate students and postdoctoral fellows from all departments and disciplines who have a draft of their teaching statement.

Please bring a draft of your teaching statement to the workshop to share.

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Nov

15

CDB Research Day

No Location - 9:00 AM - 5:00 PM

CDB will be hosting a fall Research Day on Monday, November 15, 2021 to allow trainees and faculty members to share research in a variety of formats. We encourage all trainees to participate in the this opportunity to share your work and collaborate across the Department.

Please submit your abstracts and indicate if you are interested in being considered for a talk. There will be prizes for both best trainee talks and posters. Those selected for talks are welcome to present a poster as well. Please complete this form no later than Wed, September 1st.

https://forms.gle/aiEWg6jXa8XgdFgU7

Submitted abstracts will be reviewed by the CDB Events Committee and applicants will be notified of their presentation status by September 15.

Event registration link and additional event details to follow

Please contact cdb@northwestern.edu for additional information.

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Nov

15

Department of Pharmacology Seminar - Jeff Coller, Ph.D.

Online - 4:00 PM - 5:00 PM

Jeff Coller, Ph.D.
Bloomberg Distinguished Professor of RNA Biology and Therapeutics
Johns Hopkins University

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Nov

15

Metabolism, Organelles and Membranes (MOM) Program Meeting

Chicago - 4:00 PM - 5:00 PM

Lurie Cancer Center's Membranes, Organelles and Metabolism (MOM) Program presents:

NAD+ Signaling Governs Muscle Stem Cell Clock Timing of Regeneration

Clara Peek, PhD
Assistant Professor of Biochemistry and Molecular Genetics
And Medicine (Endocrinology)
Northwestern University Feinberg School of Medicine

Maximizing the Minimum: Best Practices for Low Cell Number LC-MS Based Metabolic Analysis

Samuel Weinberg, MD, PhD
Research Fellow and Resident Physician
Laboratory of Deyu Fang, PhD
Department of Pathology
Physician Scientist Training Program
Northwestern University Feinberg School of Medicine

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Nov

16

Lurie Cancer Center Basic Research Seminar: Autophagy, Secretion and Cancer

Online - 11:00 AM - 12:00 PM

The Lurie Cancer Center Basic Research Seminar Series and the Signal Transduction and Cancer Training Program (T32 CA070085) present:

Autophagy, Secretion and Cancer

Jayanta Debnath, MD
Distinguished Professor and Chair
UCSF Department of Pathology

Tuesday, November 16, 2021
11:00 a.m. - 12:00 p.m.

Autophagy is a catabolic process where a cell literally eats itself . During autophagy, the cytoplasm and organelles in a cell are sequestered within double membrane vacuoles, called autophagosomes, and delivered to the lysosome for degradation. In eukaryotic cells, autophagy primarily functions as a critical survival response during nutrient deprivation or stress. Autophagy plays a dual role in cancer, suppressing tumor initiation by clearing damaged proteins and organelles, and also promoting tumor progression by facilitating cancer cell survival and adaptation to stress. Although traditionally viewed to be an auto-digestive pathway, recent work demonstrates that autophagy also regulates secretion. This lecture will focus on recent work to illuminate the diverse cell biological mechanisms by which the autophagy machinery promotes secretion in cancer cells as well as to define how secretory autophagy in host stromal fibroblasts influences the tumor microenvironment in vivo. These studies provide fundamental insights into how (and where) to best therapeutically target autophagy to treat human cancers.

All members of the Northwestern Medicine community are invited to attend.

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Nov

16

M-I Dept. Seminar Series - “Seeing the CNS Through The Eyes/Genetics Of HIV-1”

Chicago - 12:00 PM - 1:00 PM

Title: Seeing the CNS Through The Eyes/Genetics Of HIV-1

Ron Swanstrom, PhD

Professor
Department of Biochemistry & Biophysics, Dept. of Microbiology and Immunology,

University of North Carolina School of Medicine

Faculty Host: Mojgan Naghavi, PhD

Topic:

HIV-1 can be found in CSF throughout viral infection raising the possibility of infection within the CNS. However, the CNS environment is very different compared to the lymphoid tissues that usually support viral replication. As a result of this difference the virus both undergoes a distinct evolutionary pathway to allow long term growth in resident CNS cells, and also has distinct interactions with inflammatory cells that migrate into the CNS. These unique interactions between HIV-1 and the CNS have implications for pathogenesis and for the latent reservoir.

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Nov

17

Bacteriology Journal Club

Online - 12:00 PM - 1:00 PM

Bacteriology article presentation or research in progress from graduate students and post docs.

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Nov

17

CDB Trainee Seminars Presents: Ana Mompeon Campos, PhD, and Sraeyes Sridhar

Online - 12:00 PM - 1:00 PM

CDB Trainee Seminars Presents:

Ana Mompeon Campos, PhD, Postdoctoral Fellow, Arispe Lab
12:00-12:30 PM

Sraeyes Sridhar, Graduate Student, Mrksich Lab
12:30-1:00 PM

Zoom link sent via listserv. To subcribe to the CDB Seminar Series listserve please visit https://www.feinberg.northwestern.edu/sites/cdb/about/contact.html#listserv

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Nov

18

Immunology Journal Club

Chicago - 12:00 PM - 1:00 PM

Immunology topics presented

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Nov

18

Inclusive STEM Teaching Practices

Online - 2:00 PM - 3:30 PM

About this workshop:

From identifying course objectives to assessing student learning, inclusive practices must be planned well in advance. This is of particular importance in the context of STEM courses, where we continue to see underrepresentation of women and students from minoritized backgrounds in many disciplines. Participants will examine inclusive learning objectives and discuss ways to assess these outcomes using formative assessments. Join us for this active session.

About the Facililator:

Nancy Ruggeri, PhD, directs Graduate and Postdoctoral Learning at Searle. She holds a masters in biological anthropology and a doctorate in curriculum and instruction from the University of Wisconsin-Madison. With research experience in primate behavioral ecology and college science education, Nancy s work focuses on inclusive learning and critical thinking in STEM.

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Nov

19

24th Annual Oncology Nursing Conference

Online - 8:00 AM - 1:45 PM

On Friday, November 19, the Robert H. Lurie Comprehensive Cancer Center of Northwestern University will host the 24th Annual Oncology Nursing Conference Blueprints for Change: Adapting and Moving Forward. This year s conference will be held virtually. This highly visible and successful conference attracts more than 250 oncology nurses from throughout the Midwest and across the nation to discuss the latest topics of interest in oncology nursing.

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Nov

19

TEAM/SBDRC Seminar: Targeting Ga13 Signaling in Pancreatic Diseases

Chicago - 12:00 PM - 1:00 PM

The Robert H. Lurie Comprehensive Cancer Center of Northwestern University's Tumor Environment and Metastasis Program and the Skin Biology and Diseases Resource-Based Center present:

Targeting Ga13 Signaling in Pancreatic Diseases

Mario Shields, PhD
Research Assistant Professor
Medicine (Hematology/Oncology)
Northwestern University
Feinberg School of Medicine

Heterotrimeric G proteins carry signals from G protein coupled receptors, the largest class of cell surface proteins that play critical roles in normal and pathological processes such as cell growth, differentiation, inflammation, and cancer. Our group previously showed that G 13, a member of the G12 family of G proteins, is elevated in some human pancreatic cancer tumors and regulates invasion in vitro. As a follow up to the previous studies, G 13 was investigated in a genetic engineered mouse model of pancreatic cancer. This lecture will outline findings of an unanticipated tumor suppressor function of G 13 in pancreatic cancer. Loss of G 13 in the mouse pancreas promoted E-cadherin expression while decreasing survival in a mutant Kras/p53-driven tumor model. Furthermore, analysis of human and mouse pancreatic tumors showed loss of G 13 lead to elevated mTOR signaling. Importantly, tumors deficient in G 13 expression are sensitive to inhibition of mTOR signaling.

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Nov

22

DAAD RISE Workshop

Online - 9:00 AM - 10:00 AM

The DAAD Research Internship in Science and Engineering offers funded summer research internships at top German universities and research institutions! Open to students in STEM and Engineering fields. Current Sophomores and Juniors are eligible. Students apply to 3 opportunities that best match their area of interest. German language ability desirable, but not required.

Register here: https://northwestern.zoom.us/j/93457371787

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Nov

23

D. Z. Liebmann Fund Fellowship Information Session

Online - 12:00 PM - 1:00 PM

The Dolores Zohrab Liebmann Fund Fellowship funds graduate students only. Their priorities fall into the followign three categories:

1) Graduate school fellowships in any recognized field of study in the humanities, social sciences or natural sciences (including law, medicine, engineering, architecture or other formal professional training)
2) Independent research or study projects which must be carried out entirely in the United States of America.
3) Publications focusing on Armenian studies, Armenian history and Armenian literature of the nineteenth century or earlier. Northwestern University may select only three nomineed for this competition.

Internal Deadline: Friday, Dec. 15th @ 12:00 noon. Contact Stephen Hill (s-hill@northwestern.edu) for more information about the internal application process.

Register here: https://northwestern.zoom.us/j/97510288617

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Nov

23

M-I Dept. Seminar Series - "Antigen Persistence Leads to Unique Differentiation of Mycobacterial Lipid Antigen-Specific T Cells"

Chicago - 12:00 PM - 1:00 PM

Title:

Antigen Persistence Leads to Unique Differentiation of Mycobacterial Lpid Antigen-Specific T Cells

Speaker: Eva Morgun, Graduate Student, DGP, Lab of Dr. Chung-Ru Wang

Faculty Host: Chung-Ru Wang, PhD

Topic:

Tuberculosis remains a serious global epidemic and with the rise of multi-drug resistant strains, an efficacious vaccine solution is imperative. We have created a nanoparticle (NP) vaccine containing mycolic acid (MA), a key lipid antigen found in Mycobacterium tuberculosis. We found that MA-NP vaccination leads to a persistent depot of MA in alveolar macrophages that is able to activate MA-specific T cells 6 weeks post-vaccination. Furthermore, in this environment, MA-specific T cells acquire a T follicular-like phenotype. Antigen archiving and the associated T cell phenotype may have important implications for the efficacy and development of lipid vaccines.

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Nov

29

D. Z. Liebmann Fund Fellowship Information Session

Online - 9:00 AM - 10:00 AM

The Dolores Zohrab Liebmann Fund Fellowship funds graduate students only. Their priorities fall into the followign three categories:

1) Graduate school fellowships in any recognized field of study in the humanities, social sciences or natural sciences (including law, medicine, engineering, architecture or other formal professional training)
2) Independent research or study projects which must be carried out entirely in the United States of America.
3) Publications focusing on Armenian studies, Armenian history and Armenian literature of the nineteenth century or earlier. Northwestern University may select only three nomineed for this competition.

Internal Deadline: Friday, Dec. 15th @ 12:00 noon. Contact Stephen Hill (s-hill@northwestern.edu) for more information about the internal application process.

Register here: https://northwestern.zoom.us/j/93214052533

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Nov

30

M-I Dept. Seminar Series - "Identifying Vulnerabilities in Fungal Pathogens Through Functional and Chemical Genomic Analyses"

Chicago - 12:00 PM - 1:00 PM

Title:

"Identifying Vulnerabilities in Fungal Pathogens Through Functional and Chemical Genomic Analyses"

Leah Cowan, PhD

Associate Vice-President, Research | University of Toronto
Professor, Department of Molecular Genetics | Temerty Faculty of Medicine

Canada Research Chair in Microbial Genomics & Infectious Disease

Co-Director, CIFAR Fungal Kingdom: Threats & Opportunities

Chief Scientific Officer, Bright Angel Therapeutics

Faculty Host:

Karla Satchell, PhD

Topic:

Microbial pathogens pose a grave threat to human health. Fungal pathogens present a particular challenge because they are eukaryotes and share many of the same biological processes as the human hosts they infect. The number of drug classes that have distinct targets in fungi is very limited and the usefulness of current antifungal drugs is compromised by dose-limiting host toxicity and the frequent emergence of high-grade resistance. New, non-cross-reactive drugs for the treatment of life-threatening fungal infections are urgently needed. Here, I discuss our recent work spanning functional and chemical genomic approaches to identify novel strategies to cripple fungal pathogens. I highlight the power of chemical genomic screens to identify novel bioactive molecules and new antifungal targets. To expand the chemical space for antifungal drug development, we explore the prospects of targeting core regulators of cellular stress response for the development of resistance-evasive combination regimens. Beyond targets essential for fungal proliferation and drug resistance, we define regulators of key virulence traits, such as the capacity for morphological transitions, and identify interkingdom interactions in the microbiota that modulate these traits. Together, this work identifies vulnerabilities in fungal pathogens and provides a strategy for leveraging structure-guided drug design to develop molecules that can distinguish pathogen from host and selectively cripple fungal pathogens.

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Nov

30

DAAD RISE Workshop

Evanston - 3:00 PM - 4:00 PM

The DAAD Research Internship in Science and Engineering offers funded summer research internships at top German universities and research institutions! Open to students in STEM and Engineering fields. Current Sophomores and Juniors are eligible. Students apply to 3 opportunities that best match their area of interest. German language ability desirable, but not required.

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Dec

01

Boren Scholarships & Boren Fellowships -- Meet with Program Officers

Online - 11:00 AM - 12:00 PM

The Boren awards seek to help graduate and undergraduate students advance their proficiency in selected strategic languages through study abroad (undergrads) and langauge study & research (graduate students). At its core, Boren is a language program, thus competitive applicants will be serious students of a language not commonly taught in the United States. In addition, Boren funding comes from the US Government, thus they prize government service. All applicants must be thoughtful about how their career contributes to national security. Finally, Boren rewards long-duration study abroad. Most recipients will stay abroad for six months or more. Contact Stephen Hill in the Office of Fellowships for more information about the internal process. All Boren Awards applicants are encouraged to contact Stephen Hill for application guidance.

Register here: https://iie-org.zoom.us/j/96318916904

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Dec

01

CDB Trainee Seminars Presents: Milagros Romay, PhD, and Adriana Landeros

Online - 12:00 PM - 1:00 PM

CDB Trainee Seminars Presents:

Milagros Romay, PhD, Postdoctoral Fellow, Arispe Lab
12:00-12:30 PM

Adriana Landeros, Graduate Student, Varma Lab
12:30-1:00 PM

Zoom link sent via listserv. To subcribe to the CDB Seminar Series listserve please visit https://www.feinberg.northwestern.edu/sites/cdb/about/contact.html#listserv

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Dec

02

Immunology Journal Club

Chicago - 12:00 PM - 1:00 PM

Immunology topics presented

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Dec

02

D. Z. Liebmann Fund Fellowship Information Session

Online - 4:00 PM - 5:00 PM

The Dolores Zohrab Liebmann Fund Fellowship funds graduate students only. Their priorities fall into the followign three categories: 1) Graduate school fellowships in any recognized field of study in the humanities, social sciences or natural sciences (including law, medicine, engineering, architecture or other formal professional training)
2) Independent research or study projects which must be carried out entirely in the United States of America.
3) Publications focusing on Armenian studies, Armenian history and Armenian literature of the nineteenth century or earlier. Northwestern University may select only three nomineed for this competition.

Internal Deadline: Friday, Dec. 15th @ 12:00 noon. Contact Stephen Hill (s-hill@northwestern.edu) for more information about the internal application process.

Register here: https://northwestern.zoom.us/j/97144372928

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Dec

03

Boren Scholarships & Boren Fellowships

Evanston - 9:00 AM - 10:00 AM

The Boren awards seek to help graduate and undergraduate students advance their proficiency in selected strategic languages through study abroad (undergrads) and langauge study & research (graduate students). At its core, Boren is a language program, thus competitive applicants will be serious students of a language not commonly taught in the United States. In addition, Boren funding comes from the US Government, thus they prize government service. All applicants must be thoughtful about how their career contributes to national security. Finally, Boren rewards long-duration study abroad. Most recipients will stay abroad for six months or more. Contact Stephen Hill in the Office of Fellowships for more information about the internal process. All Boren Awards applicants are encouraged to contact Stephen Hill for application guidance.

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Dec

06

Boren Scholarships & Boren Fellowships

Evanston - 12:00 PM - 1:00 PM

The Boren awards seek to help graduate and undergraduate students advance their proficiency in selected strategic languages through study abroad (undergrads) and langauge study & research (graduate students). At its core, Boren is a language program, thus competitive applicants will be serious students of a language not commonly taught in the United States. In addition, Boren funding comes from the US Government, thus they prize government service. All applicants must be thoughtful about how their career contributes to national security. Finally, Boren rewards long-duration study abroad. Most recipients will stay abroad for six months or more. Contact Stephen Hill in the Office of Fellowships for more information about the internal process. All Boren Awards applicants are encouraged to contact Stephen Hill for application guidance.

Register here: https://northwestern.zoom.us/j/96765925565

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Dec

07

Boren Scholarships & Boren Fellowships

Evanston - 12:00 PM - 1:00 PM

The Boren awards seek to help graduate and undergraduate students advance their proficiency in selected strategic languages through study abroad (undergrads) and langauge study & research (graduate students). At its core, Boren is a language program, thus competitive applicants will be serious students of a language not commonly taught in the United States. In addition, Boren funding comes from the US Government, thus they prize government service. All applicants must be thoughtful about how their career contributes to national security. Finally, Boren rewards long-duration study abroad. Most recipients will stay abroad for six months or more. Contact Stephen Hill in the Office of Fellowships for more information about the internal process. All Boren Awards applicants are encouraged to contact Stephen Hill for application guidance.

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Dec

07

M-I Dept. Seminar Series - "Mechanisms of Replication-Coupled DNA Repair"

Online - 12:00 PM - 1:00 PM

Title:

"Mechanisms of Replication-Coupled DNA Repair"

Kavi Mehta, PhD

Post-Doctoral Fellow, Lab of David Cortez, Department of Biochemistry

Vanderbilt University School of Medicine

Faculty Host: Laimonis Laimins, PhD

Topic:

The imperative of the cell is to finish replication. Cells experience tens of thousands of DNA lesions per day that must be repaired to ensure that genetic stability is maintained. The replication stress response is required to repair DNA lesions that arise due to both endogenous sources and exogenous, including pathogens and environmental genotoxins found in water, food, and industrial chemicals. My work focuses on understanding mechanisms by which cells protect the genome from genotoxic insult such as the cytidine deaminase APOBEC3A, and how repriming events by specialized polymerases downstream from a genetic lesion are regulated.

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Dec

08

Department Faculty Meeting

No Location - 12:00 PM - 1:00 PM

Cell & Developmental Biology Department Faculty Meeting

Meeting details disseminated via listserv. If you believe you missed an announcement, please email us at cdb@northwestern.edu.

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Dec

09

Immunology Journal Club

Chicago - 12:00 PM - 1:00 PM

Immunology topics presented

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Dec

14

M-I Dept. / John Karijolich, PhD

Chicago - 12:00 PM - 1:00 PM

Title TBA

John Karijolich, PhD

Associate Professor
Department of Pathology, Microbiology, and Immunology

Vanderbilt University Medical Center

Faculty Host: Eva Gottwein, PhD

Topic:

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Dec

15

CDB Seminar Series Presents: Maria Barna, PhD, Stanford University, CA

Online - 12:00 PM - 1:00 PM

CDB EXPERTS-IN-THE-FIELD SEMINAR PRESENTATION:

Maria Barna, PhD
Associate Professor of Genetics
Genetics Department, Stanford University, Stanford California

Wednesday, December 15, 2021

12:00-1:00 PM

via Zoom

Host: Dr. Luisa Iruela-Arispe
Stephen Walter Ranson Professor and Chair
Department of Cell and Developmental Biology

For more information please contact cdb@northwestern.edu
Zoom link sent via listserv. To subcribe to the CDB Seminar Series listserve please visit https://www.feinberg.northwestern.edu/sites/cdb/about/contact.html#listserv

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Dec

16

Immunology Journal Club

Chicago - 12:00 PM - 1:00 PM

Immunology topics presented

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Dec

17

CDB Year-end Holiday Celebration

No Location - 2:00 PM - 4:00 PM

Join the Cell & Developmental Biology Department faculty, trainees, and staff for a social gathering celebrating another year of great academic research.

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Dec

22

CDB Faculty Seminars Presents: Drs. Erica Davis and Farida Korobova

Online - 12:00 PM - 1:00 PM

CDB Faculty Seminars Presents:

Dr. Erica Davis
12:00-12:30pm

Dr. Farida Korobova
12:30-1:00pm

For more information please contact cdb@northwestern.edu
Zoom link sent via listserv. Click here to subcribe to the CDB Seminar Series listserv.

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Jan

04

M-I Dept. / Andy Zloza, MD, PhD

Chicago - 12:00 PM - 1:00 PM

Title TBA

Andy Zloza, MD, PhD

Assistant Professor
Department of Internal Medicine, Division of Hematology, Oncology and Cell Therapy, Rush Medical College, Rush University

Host: Immunology Graduate Students and Postdocs, Andrew Cogswell, Coordinator

Topic:

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Jan

05

Department Faculty Meeting

No Location - 12:00 PM - 1:00 PM

Cell & Developmental Biology Department Faculty Meeting

Meeting details disseminated via listserv. If you believe you missed an announcement, please email us at cdb@northwestern.edu.

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Jan

11

M-I Dept. / Bettina Cheung

Chicago - 12:00 PM - 1:00 PM

Title TBA

Bettina Cheung, Graduate Student, DGP, Lab of Alan Hauser MD, PhD

Faculty Host: Alan Hauser, MD, PHD

Topic:

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Jan

12

CDB Seminar Series Presents: Eric Baehrecke, Ph.D., University of Massachusetts Medical School, Worcester, MA

Online - 12:00 PM - 1:00 PM

CDB EXPERTS-IN-THE-FIELD SEMINAR PRESENTATION:

Eric Baehrecke, Ph.D.
Professor
Department of Molecular, Cell and Cancer Biology
University of Massachusetts Medical School, Worcester, MA

Wednesday, January 12, 2022

12:00-1:00 PM

via Zoom

Host: Dr. Congcong He
Assistant Professor
Department of Cell and Developmental Biology

For more information please contact cdb@northwestern.edu
Zoom link sent via listserv. To subcribe to the CDB Seminar Series listserve please visit https://www.feinberg.northwestern.edu/sites/cdb/about/contact.html#listserv

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Jan

18

M-I Dept. / Pamela Bjorkman, PhD

Online - 12:00 PM - 1:00 PM

Title TBA

Pamela BJorkman, PhD

David Baltimore Professor of Biology and Bioengineering; Executive Officer for Biology and Biological Engineering

Caltech Div. of Biology and Biological Engineering

Faculty Host: Pablo Penaloza-MacMaster, PhD

Topic:

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Jan

19

CDB Faculty Seminars Presents: Drs. Rex Chisholm and Elena Martinelli

Online - 12:00 PM - 1:00 PM

CDB Faculty Seminars Presents:

Dr. Rex Chisholm
12:00-12:30pm

Dr. Elena Martinelli
12:30-1:00pm

For more information please contact cdb@northwestern.edu
Zoom link sent via listserv. Click here to subcribe to the CDB Seminar Series listserv.

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Oct

22

TEAM/SBDRC Seminar: Lectures by Irina Budunova, MD, PhD and Melissa Brown, PhD - REDD1 as Predictor of Response to Glucocorticoids and Regulator of Immune Response

No Location - 12:00 PM - 1:00 PM

The Robert H. Lurie Comprehensive Cancer Center of Northwestern University's Tumor Environment and Metastasis Program and the Skin Biology and Diseases Resource-Based Center present:

Can Early Stress-Response Gene REDD1 Dissociate Therapeutic and Adverse Effects of Glucocorticoids?

Irina Budunova, MD, PhD
Professor
Dermatology and Urology
Northwestern University
Feinberg School of Medicine

REDD1: A Potent Regulator of Adaptive and Innate Immune Responses

Melissa Brown, PhD
Professor
Microbiology-Immunology
Northwestern University
Feinberg School of Medicine

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Oct

26

Lurie Cancer Center Basic Research Seminar: Not All T Cell Responses are Created Equal

Online - 11:00 AM - 12:00 PM

The Lurie Cancer Center Basic Research Seminar Series and the Signal Transduction and Cancer Training Program (T32 CA070085) present:

Not All T Cell Responses are Created Equal

Stefani Spranger, PhD
Howard S, and Linda B. Stern
Career Development Professor Koch Institute for Integrative
Assistant Professor of Biology, MIT

Tuesday, October 26, 2021
11:00 a.m. - 12:00 p.m.

Cancer immunotherapies have revolutionized cancer treatment, but only a fraction of patients respond. The presence of CD8 cytolytic, "killer" T cells within the tumor microenvironment is a key factor in response to checkpoint blockade therapy. This talk will highlight factors that contribute to T cell exclusion from the tumor microenvironment, including tumor cell-intrinsic, tissue-macroenvironmental or environmental factors (e.g. infections). The Spranger lab studies lung and pancreatic cancer as respective models of immunotherapy sensitive and resistant cancer types.

All members of the Northwestern Medicine community are invited to attend.

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Nov

02

Translational Research in Solid Tumors (TRIST) Seminar: Precision Nanotherapeutics for Treatment of Glioblastoma

Chicago - 11:00 AM - 12:00 PM

The Translational Research in Solid Tumors (TRIST) Program presents:

Precision Nanotherapeutics for Treatment of Glioblastoma

Alexander H. Stegh, PhD
Associate Professor of Neurology (Neuro-oncology) and Medicine
The Ken & Ruth Davee Department of Neurology
Feinberg School of Medicine

The
Stegh lab, in collaboration with Dr Chad Mirkin, developed a novel
precision medicine approach for glioblastoma ( treatment involving
brain penetrant spherical nucleic acids ( conjugated with gene
regulatory siRNA or immunostimulatory DNA oligonucleotides SNAs are
modular nanostructures, composed of densely functionalized and highly
oriented nucleic acids that are spherically presented around a nanoparticle
core This unique 3 D architecture leads to biochemical and biological
properties that are radically different from linear oligonucleotides,
including delivery and privileged access to intracranial tumor sites upon
systemic administration Dr Stegh will review preclinical data that establish
SNAs as a potent gene regulatory platform that, upon IV administration,
downregulates oncogene expression in intracranial GBM Results from a
single arm, open label phase 0 first in human trial NCT 03020017 to
determine safety, pharmacokinetics, intratumoral accumulation and gene
suppressive activity of SNAs with gold nanoparticle cores, carrying siRNA
specific for the GBM oncogene Bcl 2 Like 12 will be presented The
presentation will conclude with an outlook on development of novel
immuno stimulatory SNA based therapies, including SNA architectures that
activate cGAS STING innate immunity.

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Nov

15

Metabolism, Organelles and Membranes (MOM) Program Meeting

Chicago - 4:00 PM - 5:00 PM

Lurie Cancer Center's Membranes, Organelles and Metabolism (MOM) Program presents:

NAD+ Signaling Governs Muscle Stem Cell Clock Timing of Regeneration

Clara Peek, PhD
Assistant Professor of Biochemistry and Molecular Genetics
And Medicine (Endocrinology)
Northwestern University Feinberg School of Medicine

Maximizing the Minimum: Best Practices for Low Cell Number LC-MS Based Metabolic Analysis

Samuel Weinberg, MD, PhD
Research Fellow and Resident Physician
Laboratory of Deyu Fang, PhD
Department of Pathology
Physician Scientist Training Program
Northwestern University Feinberg School of Medicine

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Nov

16

Lurie Cancer Center Basic Research Seminar: Autophagy, Secretion and Cancer

Online - 11:00 AM - 12:00 PM

The Lurie Cancer Center Basic Research Seminar Series and the Signal Transduction and Cancer Training Program (T32 CA070085) present:

Autophagy, Secretion and Cancer

Jayanta Debnath, MD
Distinguished Professor and Chair
UCSF Department of Pathology

Tuesday, November 16, 2021
11:00 a.m. - 12:00 p.m.

Autophagy is a catabolic process where a cell literally eats itself . During autophagy, the cytoplasm and organelles in a cell are sequestered within double membrane vacuoles, called autophagosomes, and delivered to the lysosome for degradation. In eukaryotic cells, autophagy primarily functions as a critical survival response during nutrient deprivation or stress. Autophagy plays a dual role in cancer, suppressing tumor initiation by clearing damaged proteins and organelles, and also promoting tumor progression by facilitating cancer cell survival and adaptation to stress. Although traditionally viewed to be an auto-digestive pathway, recent work demonstrates that autophagy also regulates secretion. This lecture will focus on recent work to illuminate the diverse cell biological mechanisms by which the autophagy machinery promotes secretion in cancer cells as well as to define how secretory autophagy in host stromal fibroblasts influences the tumor microenvironment in vivo. These studies provide fundamental insights into how (and where) to best therapeutically target autophagy to treat human cancers.

All members of the Northwestern Medicine community are invited to attend.

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Nov

19

TEAM/SBDRC Seminar: Targeting Ga13 Signaling in Pancreatic Diseases

Chicago - 12:00 PM - 1:00 PM

The Robert H. Lurie Comprehensive Cancer Center of Northwestern University's Tumor Environment and Metastasis Program and the Skin Biology and Diseases Resource-Based Center present:

Targeting Ga13 Signaling in Pancreatic Diseases

Mario Shields, PhD
Research Assistant Professor
Medicine (Hematology/Oncology)
Northwestern University
Feinberg School of Medicine

Heterotrimeric G proteins carry signals from G protein coupled receptors, the largest class of cell surface proteins that play critical roles in normal and pathological processes such as cell growth, differentiation, inflammation, and cancer. Our group previously showed that G 13, a member of the G12 family of G proteins, is elevated in some human pancreatic cancer tumors and regulates invasion in vitro. As a follow up to the previous studies, G 13 was investigated in a genetic engineered mouse model of pancreatic cancer. This lecture will outline findings of an unanticipated tumor suppressor function of G 13 in pancreatic cancer. Loss of G 13 in the mouse pancreas promoted E-cadherin expression while decreasing survival in a mutant Kras/p53-driven tumor model. Furthermore, analysis of human and mouse pancreatic tumors showed loss of G 13 lead to elevated mTOR signaling. Importantly, tumors deficient in G 13 expression are sensitive to inhibition of mTOR signaling.

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Oct

21

Biochemistry and Molecular Genetics Departmental Seminar Series: Grant D. Barish, MD, Northwestern University

Chicago - 10:00 AM - 11:00 AM

The Department of Biochemistry and Molecular Genetics presents:

Grant D. Barish, MD, Associate Professor, Endocrinology, Northwestern University

Title: Translational control of skeletal muscle mass by the transcriptional repressor BCL6

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Oct

21

Immunology Journal Club

Chicago - 12:00 PM - 1:00 PM

Immunology topics presented

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Oct

22

CDB Special Seminar: Peter Maddox, Ph.D., University of North Carolina at Chapel Hill

Off-Campus - 12:00 PM - 1:00 PM

CDB SPECIAL SEMINAR:

"New methods for LITE imaging of microtubule dynamics in the mitotic spindle reveal unsuspected behaviors"

Paul S. Maddox, Ph.D.

Associate Professor and William Burwell Harrison Scholar
Department of Biology
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina

Friday, October 22, 2021

12:00-1:00 PM

Hybrid Seminar

Location: David Hale Williams Auditorium, McGaw 2-320

Zoom Link: https://northwestern.zoom.us/j/95584864355

Meeting ID: 955 8486 4355

Password: Available upon request from cdb@northwestern.edu

Dial in Number: +1 312 626 6799 US

Abstract:

The mitotic spindle segregates the duplicated genome every cell cycle. Microtubules in the spindle bind to the kinetochore region of chromosomes and generate the force required for segregation. Microtubules are intrinsically dynamic, those bound to kinetochores exhibit suppressed dynamics and have the unusual trait of poleward microtubule flux wherein the plus ends continuously polymerize at kinetochores while the corresponding minus ends depolymerize at the spindle pole. We have developed a new single molecule imaging method for measuring poleward microtubule flux and reveal unexpected microtubule dynamics relative to kinetochores. We have modified the LITE imaging technique we pioneered several years age to remove chromatic aberration and increase power in the illumination path while maintaining limited photobleaching. The result is a light sheet capable of single molecule imaging (for SMLM super resolution and/or live cell imaging) for long periods of time. This technology opens new possibilities for live single molecule tracking of cellular events.

Hosts:

Dr. Volodya Gelfand, Professor
Department of Cell and Developmental Biology

and

Dr. Constadina Arvanitis, Research Associate Professor
Department of Cell and Developmental Biology
Director of the Center for Advanced Microscopy & Nikon Imaging Center

For more information please contact cdb@northwestern.edu
Zoom link sent via listserv. To subcribe to the CDB Seminar Series listserv please visit https://www.feinberg.northwestern.edu/sites/cdb/about/contact.html#listserv

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Oct

22

"Learning to aggress – Behavioral and circuit mechanisms of aggression reward"

Online - 12:00 PM - 1:00 PM

The Department of Neuroscience welcomes Dr. Sam A. Golden, Assistant Professor, with the University of Washington to the 2021/2022 seminar series.

Abstract

Aggression is an ethologically complex behavior with equally complex underlying mechanisms. Here, I present data on one form of aggression, appetitive or rewarding aggression, and the behavioral, cellular and system-level mechanisms guiding this behavior. First, I will present one way in which appetative aggression is modeled in mice, and extend aggression motivation to the concept of compulsive aggression seeking and relapse. I will then briefly highlight recent advances in computer vision and machine learning for automated scoring of aggressive behavior, the role of specific cell-types in controlling aggression reward, and close with preliminary data on the whole brain aggression reward functional connectome using light sheet fluorescent microscopy

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Oct

22

TEAM/SBDRC Seminar: Lectures by Irina Budunova, MD, PhD and Melissa Brown, PhD - REDD1 as Predictor of Response to Glucocorticoids and Regulator of Immune Response

No Location - 12:00 PM - 1:00 PM

The Robert H. Lurie Comprehensive Cancer Center of Northwestern University's Tumor Environment and Metastasis Program and the Skin Biology and Diseases Resource-Based Center present:

Can Early Stress-Response Gene REDD1 Dissociate Therapeutic and Adverse Effects of Glucocorticoids?

Irina Budunova, MD, PhD
Professor
Dermatology and Urology
Northwestern University
Feinberg School of Medicine

REDD1: A Potent Regulator of Adaptive and Innate Immune Responses

Melissa Brown, PhD
Professor
Microbiology-Immunology
Northwestern University
Feinberg School of Medicine

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Oct

25

"Synthetic biology approaches to retune gene regulation at the RNA level" - Bryan C. Dickinson, Ph.D.

Online - 4:00 PM - 5:00 PM

Bryan C. Dickinson, Ph.D.
Associate Professor of Chemistry
University of Chicago

Abstract: RNA transcribed from the genome in the nucleus bears little resemblance to the RNA polymer it will ultimately become in the cytoplasm where it is translated into protein. Well-known processes such as capping, splicing and polyadenylation, as well as the recently discovered and ever-expanding list of diverse chemical modifications and editing, significantly alter the properties and fates of a given RNA during the course of its lifetime. These alterations regulate critical aspects of RNA function such as stability, transport, protein binding, and translation. Especially in mammalian systems, these post-transcriptional gene expression regulatory processes are often a key determinant of genetic information flow. Moreover, from an engineering and therapeutic perspective these RNA regulatory processes represent new ways to control or retune gene expression at the RNA level, if they can be harnessed. I will present technologies our group has developed to control protein-RNA interactions with an eye toward therapeutic development.

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Oct

26

Lurie Cancer Center Basic Research Seminar: Not All T Cell Responses are Created Equal

Online - 11:00 AM - 12:00 PM

The Lurie Cancer Center Basic Research Seminar Series and the Signal Transduction and Cancer Training Program (T32 CA070085) present:

Not All T Cell Responses are Created Equal

Stefani Spranger, PhD
Howard S, and Linda B. Stern
Career Development Professor Koch Institute for Integrative
Assistant Professor of Biology, MIT

Tuesday, October 26, 2021
11:00 a.m. - 12:00 p.m.

Cancer immunotherapies have revolutionized cancer treatment, but only a fraction of patients respond. The presence of CD8 cytolytic, "killer" T cells within the tumor microenvironment is a key factor in response to checkpoint blockade therapy. This talk will highlight factors that contribute to T cell exclusion from the tumor microenvironment, including tumor cell-intrinsic, tissue-macroenvironmental or environmental factors (e.g. infections). The Spranger lab studies lung and pancreatic cancer as respective models of immunotherapy sensitive and resistant cancer types.

All members of the Northwestern Medicine community are invited to attend.

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Oct

26

M-I Dept. Seminar Series - "Using the Microbiology and Chemistry of the Built Environment to Promote Indoor Environmental Quality"

Chicago - 12:00 PM - 1:00 PM

Title: Using the Microbiology and Chemistry of the Built Environment to Promote Indoor Environmental Quality

Erica Hartmann, PhD

Assistant Professor of Civil and Environmental Engineering

Faculty Host: Alan Hauser, MD, PhD

Topic:

The built indoor environment is enriched for antibiotic-resistant pathogens compared to natural outdoor environments. Using molecular and traditional microbiology techniques, my research assesses whether synthetic antimicrobial chemicals, often included in cleaning or building products, are indeed associated with decreased microbial viability. Using simplified microbial communities and microcosm experiments, we probe causal relationships between exposure to antimicrobial chemicals and the development of different resistance phenotypes and genotypes. Based on these findings, we are assessing new, bio-inspired approaches to controlling microbial communities.

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Oct

27

Bacteriology Journal Club

Chicago - 12:00 PM - 1:00 PM

Bacteriology article presentation or research in progress from graduate students and post docs.

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Oct

27

CDB Trainee Seminars Presents: Myung-Su Kang, PhD and Hannah Sunshine

Online - 12:00 PM - 1:00 PM

CDB Trainee Seminars Presents:

"Autism-like behavior caused by the disruption of the autophagic Beclin 1"

Myung-Su Kang, PhD, Postdoctoral Fellow, He Lab
12:00-12:30 PM

"ZFP36 mediated regulation of endothelial activation for neovascularization"

Hannah Sunshine, Graduate Student, Arispe Lab
12:30-1:00 PM

Zoom link sent via listserv. To subcribe to the CDB Seminar Series listserve please visit https://www.feinberg.northwestern.edu/sites/cdb/about/contact.html#listserv

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Oct

27

DAAD RISE Workshop

No Location - 12:00 PM - 1:00 PM

The DAAD Research Internship in Science and Engineering offers funded summer research internships at top German universities and research institutions! Open to students in STEM and Engineering fields. Current Sophomores and Juniors are eligible. Students apply to 3 opportunities that best match their area of interest. German language ability desirable, but not required. Register here: https://northwestern.zoom.us/j/91988238559

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Oct

27

Cancer Connections

Online - 5:45 PM - 7:30 PM

At the Lurie Cancer Center, your treatment plan includes care for the mind, body and spirit. Cancer Connections is just what the doctor ordered, introducing tools, techniques and services you can use to reenergize during and after treatment. Patients and caregivers are invited to attend our virtual programs and learn from cancer experts and find local and national support resources available to both patients and caregivers.

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Oct

28

Biochemistry and Molecular Genetics Departmental Seminar Series: Jon Coloff, PhD, UIC

Chicago - 10:00 AM - 11:00 AM

The Department of Biochemistry and Molecular Genetics presents:

Jon Colloff, Assistant Professor, Physiology & Biophysics, University of Illinois, Chicago

Title: "Targeting Serine Auxotrophy in Luminal Breast Cancer"

Abstract:

A major challenge of targeting metabolism for cancer therapy is pathway redundancy, where multiple sources of critical nutrients can diminish the effects of metabolic therapies. An example of this can be found in recent attempts to target the serine synthesis pathway for cancer therapy, where the abundance of serine available to be taken up from the circulation has hampered the success of inhibitors of serine biosynthesis. This places a premium on pursuing strategies of limiting pathway redundancy if we wish to successfully target serine and other critical metabolic pathways for cancer therapy. We have taken the approach of analyzing human tumor gene expression data to identify scenarios where pathway redundancy is limited due to lineage-dependent gene expression, thereby creating potential vulnerabilities. Using this approach, we have found that the two major lineages of breast tumors luminal and basal express vastly different levels of PSAT1 (phosphoserine aminotransferase 1), the gene encoding the second enzyme of the serine synthesis pathway. Luminal breast cancer cells, which express extremely low levels of PSAT1, are unable to activate the serine synthesis pathway even when extracellular serine is completely absent. As a result, they are entirely dependent on exogenous serine for proliferation and survival and are sensitive to dietary serine and glycine starvation. This is in contrast to basal breast cancer cells, which are able to synthesize serine and proliferate in the absence of extracellular serine. Mechanistically, this serine auxotrophy is due to lineage-specific methylation of the PSAT1 gene in luminal breast tumors. Interestingly, the PSAT1 methylation and expression phenotypes observed in human breast tumors pre-exist in the cells-of-origin for these tumors in the normal mammary gland, emphasizing the importance of cell lineage in dictating this phenotype. Ongoing work in the Coloff Lab is continuing to characterize serine auxotrophy as a potentially targetable vulnerability of luminal breast tumors.

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Oct

28

Immunology Journal Club

Chicago - 12:00 PM - 1:00 PM

Immunology topics presented

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Oct

29

BMG Departmental Journal Club

Chicago - 1:00 PM - 2:00 PM

Presenter:

Bercin Cenik, Postdoctoral Scholar, Shilatifard Lab, Biochemistry and Molecular Genetics

Milad Alasady, Postdoctoral Scholar, Mendillo Lab, Biochemistry and Molecular Genetics

The BMG Journal Club is an opportunity for the department to come together and have in-depth discussions about the current literature and the overall implications of new studies, enhancing everyone s knowledge of the field at large and about each other s research interests within the department; providing possible opportunities to collaborate as well. This is also an opportunity to practice vital presentation skills in front of a friendly audience.

Refreshments will be provided.

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Nov

01

Germany Alumni Panel

Evanston - 4:30 PM - 5:30 PM

Listen to a panel of Wildcats who spent time in Germany discuss their experiences! Germany offers multiple ways to study, research, and engage. On this panel, hear the expereinces of people who have won fellowships and completed study abroad! Open to students in all fields. German language ability desirable, but not required. Bring your interest to explore and learn outside the US!

*** This event will take place both in person and online. To attend in person, go to Kresge 1-515. You need not register to attend in person. To attend online, register here: https://northwestern.zoom.us/j/98113327328

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Nov

02

Translational Research in Solid Tumors (TRIST) Seminar: Precision Nanotherapeutics for Treatment of Glioblastoma

Chicago - 11:00 AM - 12:00 PM

The Translational Research in Solid Tumors (TRIST) Program presents:

Precision Nanotherapeutics for Treatment of Glioblastoma

Alexander H. Stegh, PhD
Associate Professor of Neurology (Neuro-oncology) and Medicine
The Ken & Ruth Davee Department of Neurology
Feinberg School of Medicine

The
Stegh lab, in collaboration with Dr Chad Mirkin, developed a novel
precision medicine approach for glioblastoma ( treatment involving
brain penetrant spherical nucleic acids ( conjugated with gene
regulatory siRNA or immunostimulatory DNA oligonucleotides SNAs are
modular nanostructures, composed of densely functionalized and highly
oriented nucleic acids that are spherically presented around a nanoparticle
core This unique 3 D architecture leads to biochemical and biological
properties that are radically different from linear oligonucleotides,
including delivery and privileged access to intracranial tumor sites upon
systemic administration Dr Stegh will review preclinical data that establish
SNAs as a potent gene regulatory platform that, upon IV administration,
downregulates oncogene expression in intracranial GBM Results from a
single arm, open label phase 0 first in human trial NCT 03020017 to
determine safety, pharmacokinetics, intratumoral accumulation and gene
suppressive activity of SNAs with gold nanoparticle cores, carrying siRNA
specific for the GBM oncogene Bcl 2 Like 12 will be presented The
presentation will conclude with an outlook on development of novel
immuno stimulatory SNA based therapies, including SNA architectures that
activate cGAS STING innate immunity.

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Nov

02

M-I Dept. Seminar Series - "Phenotypic Heterogeneity in Clostridioides difficile"

Chicago - 12:00 PM - 1:00 PM

Title: Phenotypic Heterogeneity in Clostridioides difficile

Rita Tamayo, PhD

Associate Professor, Dept. of Microbiology and Immunology, University of North Carolina School of Medicine

Faculty Host: Hank Seifert

Topic:

Clostridioides difficile causes antibiotic-associated disease ranging from mild diarrhea to potentially fatal pseudomembranous colitis, and it is one of the most common causes of nosocomial infections in the U.S. Recent work from our lab and others has shown that C. difficile generates extensive phenotypic heterogeneity through the process of phase variation. This talk will present some of our latest work uncovering the mechanisms and consequences of phase variation in C. difficile physiology and virulence, highlighting the ways in which this process in C. difficile differs from systems described in other bacteria.

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Nov

02

Truman Scholarship Information Session

Online - 12:00 PM - 1:00 PM

The Harry S. Truman Scholarship Foundation supports the graduate education and professional development of outstanding young people committed to public service leadership.

Learn more about the Truman Scholarship and application process by registering for this information session, offered by the Northwestern Office of Fellowships. Please register using your Northwestern email address. Register here.

Find helpful Truman Scholarship documents on the Office of Fellowships Info Sessions website here.

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Nov

03

Bacteriology Journal Club

Chicago - 12:00 PM - 1:00 PM

Bacteriology article presentation or research in progress from graduate students and post docs.

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Nov

03

Department Faculty Meeting

No Location - 12:00 PM - 1:00 PM

Cell & Developmental Biology Department Faculty Meeting

Meeting details disseminated via listserv. If you believe you missed an announcement, please email us at cdb@northwestern.edu.

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Nov

04

Biochemistry and Molecular Genetics Departmental Seminar Series: Alex Ruthenberg, PhD, UIC

Chicago - 10:00 AM - 11:00 AM

The Department of Biochemistry and Molecular Genetics presents:

Alex Ruthenberg, Associate Professor, Cell and Molecular Biology

University of Illinois, Chicago

Title: "Bivalency and its Discontents: Subjecting the Dogma to Quantitative Analysis"

Abstract:

Nucleosomes, composed of DNA and histone proteins, represent the fundamental repeating unit of the eukaryotic genome; posttranslational modifications of these histone proteins are thought to influence the activity of the associated genomic regions to regulate cell identity. Traditionally, trimethylation of histone H3K4 (H3K4me3) is associated with transcriptional initiation, whereas trimethylation of H3K27 (H3K27me3) is considered transcriptionally repressive. The apparent juxtaposition of these opposing marks, termed bivalent domains , was proposed to specifically demarcate of small set transcriptionally-poised lineage-commitment genes that resolve to one constituent modification through differentiation, thereby determining transcriptional status. Since then, many thousands of studies have canonized the bivalency model as a chromatin hallmark of development in many cell types. However, these conclusions are largely based on chromatin immunoprecipitations (ChIP) with significant methodological problems hampering their interpretation. Absent direct quantitative measurements, it has been difficult to evaluate the strength of the bivalency model. Here, we present reICeChIP, a calibrated sequential ChIP method to quantitatively measure nucleosomes with H3K4me3 and H3K27me3 genome-wide, addressing the limitations of prior measurements. With reICeChIP, we profile bivalency through the differentiation paradigm that first established this model: from na ve mouse embryonic stem cells (mESCs) into neuronal progenitor cells (NPCs). Our results cast doubt on every aspect of the bivalency model; in this context, we find that bivalency is widespread rather than restricted to early developmental genes, bivalency does not resolve with differentiation, but increases instead, and is neither sensitive nor specific for identifying poised developmental genes or gene expression status more broadly. Our findings caution against imbuing bivalent domains as meaningful markers of developmentally poised genes.

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Nov

04

CDB Trainee Meeting: Talk Mechanics

No Location - 12:00 PM - 1:00 PM

CDB Trainee Meeting: Talk Mechanics

This session is part of CDB's quarterly Trainee Seminar Series training meetings

Please join us for a discussion of best practices when preparing and giving effective presentations, focusing specifically on the mechanics that make a "good" talk.

Thursday, November 4, 2021

12:00-1:00pm

Location TBA

Meeting details will be shared via listserv. Please contact cdb@northwestern.edu for more information.

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Nov

04

Immunology Journal Club

Chicago - 12:00 PM - 1:00 PM

Immunology topics presented

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Nov

05

Cancer Survivorship Symposium

Online - 8:30 AM - 3:00 PM

On Friday, November 5, the virtual Cancer Survivorship Symposium will bring together researchers, clinicians and other healthcare professionals interested in improving outcomes for cancer survivors and implementing best practice models to optimize patient outcomes. Participants will hear presentations and engage in discussions focused on supporting evidence-based, equitable cancer survivorship care.

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Nov

09

M-I Dept. Seminar Series - “Decrypting Microbiologic Aspects of Periprosthetic Joint Infection”

Chicago - 12:00 PM - 1:00 PM

Title: Decrypting Microbiologic Aspects of Periprosthetic Joint Infection

Robin Patel, MD, Mayo Clinic

Director, Infectious Diseases Research Laboratory, and Chair, Division of Clinical Microbiology

Faculty Host: Karla Satchel, PhD

Topic:

Periprosthetic joint infection is a biofilm-associated infection caused by a multitude of bacterial species. In this presentation, the epidemiology, microbiology, and pathogenesis of periprosthetic joint infection will be presented. Insight into pathogenesis of arthroplasty failure provided by metagenomic shotgun whole genome sequencing will be shared.

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Nov

10

Biochemistry and Molecular Genetics Departmental Seminar Series: Kenneth Zaret, PhD, University of Pennsylvania

Chicago - 10:00 AM - 11:00 AM

The Department of Biochemistry and Molecular Genetics presents:

Kenneth Zaret, Joseph Ledy Professor, Department of Cell and Developmental Biology

University of Pennsylvania

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Nov

10

Biochemistry and Molecular Genetics Departmental Seminar Series: Kenneth Zaret, PhD, University of Pennsylvania [copy]

Chicago - 10:00 AM - 11:00 AM

The Department of Biochemistry and Molecular Genetics presents:

Kenneth Zaret, Joseph Ledy Professor, Department of Cell and Developmental Biology

University of Pennsylvania

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Nov

10

Bacteriology Journal Club

Chicago - 12:00 PM - 1:00 PM

Bacteriology article presentation or research in progress from graduate students and post docs.

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Nov

10

CDB Seminar Series Presents: "Chromosome dynamics during the cell cycle," Daniel Gerlich, PhD, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna, Austria

Online - 12:00 PM - 1:00 PM

CDB EXPERTS-IN-THE-FIELD SEMINAR PRESENTATION:

"Chromosome dynamics during the cell cycle"

Daniel Gerlich, PhD
Senior Research Group Leader
Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA),
Vienna, Austria

Wednesday, November 10, 2021

12:00-1:00 PM

Zoom Link: https://northwestern.zoom.us/j/94371859347

Meeting ID: 943 7185 9347

Password: Available upon request from cdb@northwestern.edu

Dial in Number: +1 312 626 6799 US
+43 72 011 5988 Austria

Relevant Publications:

S. Cuylen-Haering, M. Petrovic, A. Hernandez-Armendariz, M.W. G. Schneider, M. Samwer, C. Blaukopf, L.J. Holt, D.W. Gerlich. Chromosome clustering by Ki-67 excludes cytoplasm during nuclear assembly. Nature (2020). 587(7833): 285-290. doi: 10.1038/s41586-020-2672-3.

M. Mitter, C. Gasser, Z. Takacs, C. C. H. Langer, W. Tang, G. Jessberger, C. T. Beales, E. Neuner, S. L. Ameres, J.-M. Peters, A. Goloborodko, R. Micura, Daniel W. Gerlich. Conformation of sister chromatids in the replicated human genome. Nature (2020). 586(7827): 139-144. doi: 10.1038/s41586-020-2744-4.

P. Batty, D.W. Gerlich. Mitotic Chromosome Mechanics: How Cells Segregate Their Genome. Trends Cell Biol (2019). 29(9): 717-726. doi: 10.1016/j.tcb.2019.05.007.

Host: Dr. Dileep Varma, Assistant Professor
Department of Cell and Developmental Biology

For more information please contact cdb@northwestern.edu
Zoom link sent via listserv. To subcribe to the CDB Seminar Series listserve please visit https://www.feinberg.northwestern.edu/sites/cdb/about/contact.html#listserv

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Nov

11

Immunology Journal Club

Chicago - 12:00 PM - 1:00 PM

Immunology topics presented

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Nov

11

Symposium in honor of Dr. Jonathan Leis on his transition to Emeritus

Online - 12:00 PM - 2:00 PM

Please join us for a symposium honoring Jonathan P. Leis, PhD, professor of Microbiology-Immunology and former executive associate dean for research at Northwestern University Feinberg School of Medicine.

Schedule:

Noon - 12:05 p.m. CT Welcome
Laimonis Laimins, PhD
Guy and Anne Youmans Professor and Chair of Microbiology-Immunology
Northwestern University Feinberg School of Medicine

12:05 - 12:40 p.m. CT My career-long fascination with antiviral therapeutics
Craig Cameron, PhD
Professor and Chair of Microbiology and Immunology
University of North Carolina School of Medicine

12:45 - 1:20 p.m. CT Co-Transcriptional Recognition of Functional Splice Sites in Mammalian Genomes
Xiang-Dong Fu, PhD
Distinguished Professor of Cellular and Molecular Medicine
University of California, San Diego

1:25 - 2 p.m. CT The winding road from poxvirus host range factors to novel myeloid tumor suppressors
Yan Xiang, PhD
Professor of Microbiology and Immunology & Molecular Genetics
UT Health San Antonio

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Nov

11

DAAD RISE Workshop

Evanston - 4:00 PM - 5:00 PM

The DAAD Research Internship in Science and Engineering offers funded summer research internships at top German universities and research institutions! Open to students in STEM and Engineering fields. Current Sophomores and Juniors are eligible. Students apply to 3 opportunities that best match their area of interest. German language ability desirable, but not required.

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Nov

12

5th Annual Translational Bridge Symposium

Chicago - 9:00 AM - 12:30 PM

The Robert H. Lurie Comprehensive Cancer Center of Northwestern University is committed to fostering collaborations between physicians and basic scientists to advance translational cancer research with the ultimate goal of translating basic science discoveries to the clinic and impacting cancer patient outcomes. Designed to stimulate collaboration between basic scientists, population scientists, and translational clinical investigators, this symposium will feature brief presentations by scientists and clinical investigators on research discoveries with potential for clinical trial development.

This meeting is currently scheduled to be in person with a Zoom option for remove viewing. Updates will be provided to registrants in November. Registration is complimentary, but advance registration is required.

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Nov

12

Writing Your Teaching Statement: Peer Review

Online - 10:00 AM - 12:00 PM

Teaching statements are an important component of many academic job applications, but they can be challenging to write. Receiving feedback from peers can provide you with recommendations on how to clarify and improve your main claims about your teaching. Allowing others to read your writing can also give you critical insight into how your target audience may understand and interpret your claims, which can help further refine your teaching statement.

In this workshop, participants will share their teaching statement drafts and engage in guided peer feedback.

This workshop is open to graduate students and postdoctoral fellows from all departments and disciplines who have a draft of their teaching statement.

Please bring a draft of your teaching statement to the workshop to share.

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Nov

12

BMG Departmental Journal Club

Chicago - 1:00 PM - 2:00 PM

Presenters:

Marc Morgan, Research Assistant Professor, Shilatifard Lab, Biochemistry and Molecular Genetics

Alex Lee, Graduate Student, Foltz Lab, Biochemisty and Molecular Genetics

The BMG Journal Club is an opportunity for the department to come together and have in-depth discussions about the current literature and the overall implications of new studies, enhancing everyone s knowledge of the field at large and about each other s research interests within the department; providing possible opportunities to collaborate as well. This is also an opportunity to practice vital presentation skills in front of a friendly audience.

Refreshments will be provided.

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Nov

15

CDB Research Day

No Location - 9:00 AM - 5:00 PM

CDB will be hosting a fall Research Day on Monday, November 15, 2021 to allow trainees and faculty members to share research in a variety of formats. We encourage all trainees to participate in the this opportunity to share your work and collaborate across the Department.

Please submit your abstracts and indicate if you are interested in being considered for a talk. There will be prizes for both best trainee talks and posters. Those selected for talks are welcome to present a poster as well. Please complete this form no later than Wed, September 1st.

https://forms.gle/aiEWg6jXa8XgdFgU7

Submitted abstracts will be reviewed by the CDB Events Committee and applicants will be notified of their presentation status by September 15.

Event registration link and additional event details to follow

Please contact cdb@northwestern.edu for additional information.

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Nov

15

Department of Pharmacology Seminar - Jeff Coller, Ph.D.

Online - 4:00 PM - 5:00 PM

Jeff Coller, Ph.D.
Bloomberg Distinguished Professor of RNA Biology and Therapeutics
Johns Hopkins University

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Nov

15

Metabolism, Organelles and Membranes (MOM) Program Meeting

Chicago - 4:00 PM - 5:00 PM

Lurie Cancer Center's Membranes, Organelles and Metabolism (MOM) Program presents:

NAD+ Signaling Governs Muscle Stem Cell Clock Timing of Regeneration

Clara Peek, PhD
Assistant Professor of Biochemistry and Molecular Genetics
And Medicine (Endocrinology)
Northwestern University Feinberg School of Medicine

Maximizing the Minimum: Best Practices for Low Cell Number LC-MS Based Metabolic Analysis

Samuel Weinberg, MD, PhD
Research Fellow and Resident Physician
Laboratory of Deyu Fang, PhD
Department of Pathology
Physician Scientist Training Program
Northwestern University Feinberg School of Medicine

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Nov

16

Lurie Cancer Center Basic Research Seminar: Autophagy, Secretion and Cancer

Online - 11:00 AM - 12:00 PM

The Lurie Cancer Center Basic Research Seminar Series and the Signal Transduction and Cancer Training Program (T32 CA070085) present:

Autophagy, Secretion and Cancer

Jayanta Debnath, MD
Distinguished Professor and Chair
UCSF Department of Pathology

Tuesday, November 16, 2021
11:00 a.m. - 12:00 p.m.

Autophagy is a catabolic process where a cell literally eats itself . During autophagy, the cytoplasm and organelles in a cell are sequestered within double membrane vacuoles, called autophagosomes, and delivered to the lysosome for degradation. In eukaryotic cells, autophagy primarily functions as a critical survival response during nutrient deprivation or stress. Autophagy plays a dual role in cancer, suppressing tumor initiation by clearing damaged proteins and organelles, and also promoting tumor progression by facilitating cancer cell survival and adaptation to stress. Although traditionally viewed to be an auto-digestive pathway, recent work demonstrates that autophagy also regulates secretion. This lecture will focus on recent work to illuminate the diverse cell biological mechanisms by which the autophagy machinery promotes secretion in cancer cells as well as to define how secretory autophagy in host stromal fibroblasts influences the tumor microenvironment in vivo. These studies provide fundamental insights into how (and where) to best therapeutically target autophagy to treat human cancers.

All members of the Northwestern Medicine community are invited to attend.

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Nov

16

M-I Dept. Seminar Series - “Seeing the CNS Through The Eyes/Genetics Of HIV-1”

Chicago - 12:00 PM - 1:00 PM

Title: Seeing the CNS Through The Eyes/Genetics Of HIV-1

Ron Swanstrom, PhD

Professor
Department of Biochemistry & Biophysics, Dept. of Microbiology and Immunology,

University of North Carolina School of Medicine

Faculty Host: Mojgan Naghavi, PhD

Topic:

HIV-1 can be found in CSF throughout viral infection raising the possibility of infection within the CNS. However, the CNS environment is very different compared to the lymphoid tissues that usually support viral replication. As a result of this difference the virus both undergoes a distinct evolutionary pathway to allow long term growth in resident CNS cells, and also has distinct interactions with inflammatory cells that migrate into the CNS. These unique interactions between HIV-1 and the CNS have implications for pathogenesis and for the latent reservoir.

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Nov

17

Bacteriology Journal Club

Online - 12:00 PM - 1:00 PM

Bacteriology article presentation or research in progress from graduate students and post docs.

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Nov

17

CDB Trainee Seminars Presents: Ana Mompeon Campos, PhD, and Sraeyes Sridhar

Online - 12:00 PM - 1:00 PM

CDB Trainee Seminars Presents:

Ana Mompeon Campos, PhD, Postdoctoral Fellow, Arispe Lab
12:00-12:30 PM

Sraeyes Sridhar, Graduate Student, Mrksich Lab
12:30-1:00 PM

Zoom link sent via listserv. To subcribe to the CDB Seminar Series listserve please visit https://www.feinberg.northwestern.edu/sites/cdb/about/contact.html#listserv

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Nov

18

Immunology Journal Club

Chicago - 12:00 PM - 1:00 PM

Immunology topics presented

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Nov

18

Inclusive STEM Teaching Practices

Online - 2:00 PM - 3:30 PM

About this workshop:

From identifying course objectives to assessing student learning, inclusive practices must be planned well in advance. This is of particular importance in the context of STEM courses, where we continue to see underrepresentation of women and students from minoritized backgrounds in many disciplines. Participants will examine inclusive learning objectives and discuss ways to assess these outcomes using formative assessments. Join us for this active session.

About the Facililator:

Nancy Ruggeri, PhD, directs Graduate and Postdoctoral Learning at Searle. She holds a masters in biological anthropology and a doctorate in curriculum and instruction from the University of Wisconsin-Madison. With research experience in primate behavioral ecology and college science education, Nancy s work focuses on inclusive learning and critical thinking in STEM.

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Nov

19

24th Annual Oncology Nursing Conference

Online - 8:00 AM - 1:45 PM

On Friday, November 19, the Robert H. Lurie Comprehensive Cancer Center of Northwestern University will host the 24th Annual Oncology Nursing Conference Blueprints for Change: Adapting and Moving Forward. This year s conference will be held virtually. This highly visible and successful conference attracts more than 250 oncology nurses from throughout the Midwest and across the nation to discuss the latest topics of interest in oncology nursing.

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Nov

19

TEAM/SBDRC Seminar: Targeting Ga13 Signaling in Pancreatic Diseases

Chicago - 12:00 PM - 1:00 PM

The Robert H. Lurie Comprehensive Cancer Center of Northwestern University's Tumor Environment and Metastasis Program and the Skin Biology and Diseases Resource-Based Center present:

Targeting Ga13 Signaling in Pancreatic Diseases

Mario Shields, PhD
Research Assistant Professor
Medicine (Hematology/Oncology)
Northwestern University
Feinberg School of Medicine

Heterotrimeric G proteins carry signals from G protein coupled receptors, the largest class of cell surface proteins that play critical roles in normal and pathological processes such as cell growth, differentiation, inflammation, and cancer. Our group previously showed that G 13, a member of the G12 family of G proteins, is elevated in some human pancreatic cancer tumors and regulates invasion in vitro. As a follow up to the previous studies, G 13 was investigated in a genetic engineered mouse model of pancreatic cancer. This lecture will outline findings of an unanticipated tumor suppressor function of G 13 in pancreatic cancer. Loss of G 13 in the mouse pancreas promoted E-cadherin expression while decreasing survival in a mutant Kras/p53-driven tumor model. Furthermore, analysis of human and mouse pancreatic tumors showed loss of G 13 lead to elevated mTOR signaling. Importantly, tumors deficient in G 13 expression are sensitive to inhibition of mTOR signaling.

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Nov

22

DAAD RISE Workshop

Online - 9:00 AM - 10:00 AM

The DAAD Research Internship in Science and Engineering offers funded summer research internships at top German universities and research institutions! Open to students in STEM and Engineering fields. Current Sophomores and Juniors are eligible. Students apply to 3 opportunities that best match their area of interest. German language ability desirable, but not required.

Register here: https://northwestern.zoom.us/j/93457371787

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Nov

23

D. Z. Liebmann Fund Fellowship Information Session

Online - 12:00 PM - 1:00 PM

The Dolores Zohrab Liebmann Fund Fellowship funds graduate students only. Their priorities fall into the followign three categories:

1) Graduate school fellowships in any recognized field of study in the humanities, social sciences or natural sciences (including law, medicine, engineering, architecture or other formal professional training)
2) Independent research or study projects which must be carried out entirely in the United States of America.
3) Publications focusing on Armenian studies, Armenian history and Armenian literature of the nineteenth century or earlier. Northwestern University may select only three nomineed for this competition.

Internal Deadline: Friday, Dec. 15th @ 12:00 noon. Contact Stephen Hill (s-hill@northwestern.edu) for more information about the internal application process.

Register here: https://northwestern.zoom.us/j/97510288617

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Nov

23

M-I Dept. Seminar Series - "Antigen Persistence Leads to Unique Differentiation of Mycobacterial Lipid Antigen-Specific T Cells"

Chicago - 12:00 PM - 1:00 PM

Title:

Antigen Persistence Leads to Unique Differentiation of Mycobacterial Lpid Antigen-Specific T Cells

Speaker: Eva Morgun, Graduate Student, DGP, Lab of Dr. Chung-Ru Wang

Faculty Host: Chung-Ru Wang, PhD

Topic:

Tuberculosis remains a serious global epidemic and with the rise of multi-drug resistant strains, an efficacious vaccine solution is imperative. We have created a nanoparticle (NP) vaccine containing mycolic acid (MA), a key lipid antigen found in Mycobacterium tuberculosis. We found that MA-NP vaccination leads to a persistent depot of MA in alveolar macrophages that is able to activate MA-specific T cells 6 weeks post-vaccination. Furthermore, in this environment, MA-specific T cells acquire a T follicular-like phenotype. Antigen archiving and the associated T cell phenotype may have important implications for the efficacy and development of lipid vaccines.

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Nov

29

D. Z. Liebmann Fund Fellowship Information Session

Online - 9:00 AM - 10:00 AM

The Dolores Zohrab Liebmann Fund Fellowship funds graduate students only. Their priorities fall into the followign three categories:

1) Graduate school fellowships in any recognized field of study in the humanities, social sciences or natural sciences (including law, medicine, engineering, architecture or other formal professional training)
2) Independent research or study projects which must be carried out entirely in the United States of America.
3) Publications focusing on Armenian studies, Armenian history and Armenian literature of the nineteenth century or earlier. Northwestern University may select only three nomineed for this competition.

Internal Deadline: Friday, Dec. 15th @ 12:00 noon. Contact Stephen Hill (s-hill@northwestern.edu) for more information about the internal application process.

Register here: https://northwestern.zoom.us/j/93214052533

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Nov

30

M-I Dept. Seminar Series - "Identifying Vulnerabilities in Fungal Pathogens Through Functional and Chemical Genomic Analyses"

Chicago - 12:00 PM - 1:00 PM

Title:

"Identifying Vulnerabilities in Fungal Pathogens Through Functional and Chemical Genomic Analyses"

Leah Cowan, PhD

Associate Vice-President, Research | University of Toronto
Professor, Department of Molecular Genetics | Temerty Faculty of Medicine

Canada Research Chair in Microbial Genomics & Infectious Disease

Co-Director, CIFAR Fungal Kingdom: Threats & Opportunities

Chief Scientific Officer, Bright Angel Therapeutics

Faculty Host:

Karla Satchell, PhD

Topic:

Microbial pathogens pose a grave threat to human health. Fungal pathogens present a particular challenge because they are eukaryotes and share many of the same biological processes as the human hosts they infect. The number of drug classes that have distinct targets in fungi is very limited and the usefulness of current antifungal drugs is compromised by dose-limiting host toxicity and the frequent emergence of high-grade resistance. New, non-cross-reactive drugs for the treatment of life-threatening fungal infections are urgently needed. Here, I discuss our recent work spanning functional and chemical genomic approaches to identify novel strategies to cripple fungal pathogens. I highlight the power of chemical genomic screens to identify novel bioactive molecules and new antifungal targets. To expand the chemical space for antifungal drug development, we explore the prospects of targeting core regulators of cellular stress response for the development of resistance-evasive combination regimens. Beyond targets essential for fungal proliferation and drug resistance, we define regulators of key virulence traits, such as the capacity for morphological transitions, and identify interkingdom interactions in the microbiota that modulate these traits. Together, this work identifies vulnerabilities in fungal pathogens and provides a strategy for leveraging structure-guided drug design to develop molecules that can distinguish pathogen from host and selectively cripple fungal pathogens.

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Nov

30

DAAD RISE Workshop

Evanston - 3:00 PM - 4:00 PM

The DAAD Research Internship in Science and Engineering offers funded summer research internships at top German universities and research institutions! Open to students in STEM and Engineering fields. Current Sophomores and Juniors are eligible. Students apply to 3 opportunities that best match their area of interest. German language ability desirable, but not required.

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Dec

01

Boren Scholarships & Boren Fellowships -- Meet with Program Officers

Online - 11:00 AM - 12:00 PM

The Boren awards seek to help graduate and undergraduate students advance their proficiency in selected strategic languages through study abroad (undergrads) and langauge study & research (graduate students). At its core, Boren is a language program, thus competitive applicants will be serious students of a language not commonly taught in the United States. In addition, Boren funding comes from the US Government, thus they prize government service. All applicants must be thoughtful about how their career contributes to national security. Finally, Boren rewards long-duration study abroad. Most recipients will stay abroad for six months or more. Contact Stephen Hill in the Office of Fellowships for more information about the internal process. All Boren Awards applicants are encouraged to contact Stephen Hill for application guidance.

Register here: https://iie-org.zoom.us/j/96318916904

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Dec

01

CDB Trainee Seminars Presents: Milagros Romay, PhD, and Adriana Landeros

Online - 12:00 PM - 1:00 PM

CDB Trainee Seminars Presents:

Milagros Romay, PhD, Postdoctoral Fellow, Arispe Lab
12:00-12:30 PM

Adriana Landeros, Graduate Student, Varma Lab
12:30-1:00 PM

Zoom link sent via listserv. To subcribe to the CDB Seminar Series listserve please visit https://www.feinberg.northwestern.edu/sites/cdb/about/contact.html#listserv

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Dec

02

Biochemistry and Molecular Genetics Departmental Seminar Series: Keara Lane, PhD, Northwestern University

Chicago - 10:00 AM - 11:00 AM

The Department of Biochemistry and Molecular Genetics presents:

Keara Lane, Assistant Professor, Molecular Biosciences, Northwestern University

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Dec

02

Immunology Journal Club

Chicago - 12:00 PM - 1:00 PM

Immunology topics presented

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Dec

02

D. Z. Liebmann Fund Fellowship Information Session

Online - 4:00 PM - 5:00 PM

The Dolores Zohrab Liebmann Fund Fellowship funds graduate students only. Their priorities fall into the followign three categories: 1) Graduate school fellowships in any recognized field of study in the humanities, social sciences or natural sciences (including law, medicine, engineering, architecture or other formal professional training)
2) Independent research or study projects which must be carried out entirely in the United States of America.
3) Publications focusing on Armenian studies, Armenian history and Armenian literature of the nineteenth century or earlier. Northwestern University may select only three nomineed for this competition.

Internal Deadline: Friday, Dec. 15th @ 12:00 noon. Contact Stephen Hill (s-hill@northwestern.edu) for more information about the internal application process.

Register here: https://northwestern.zoom.us/j/97144372928

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Dec

03

Boren Scholarships & Boren Fellowships

Evanston - 9:00 AM - 10:00 AM

The Boren awards seek to help graduate and undergraduate students advance their proficiency in selected strategic languages through study abroad (undergrads) and langauge study & research (graduate students). At its core, Boren is a language program, thus competitive applicants will be serious students of a language not commonly taught in the United States. In addition, Boren funding comes from the US Government, thus they prize government service. All applicants must be thoughtful about how their career contributes to national security. Finally, Boren rewards long-duration study abroad. Most recipients will stay abroad for six months or more. Contact Stephen Hill in the Office of Fellowships for more information about the internal process. All Boren Awards applicants are encouraged to contact Stephen Hill for application guidance.

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Dec

03

BMG Departmental Journal Club

Chicago - 1:00 PM - 2:00 PM

Presenters:

Yohhei Takahashi, Research Assistant Professor, Shilatifard Lab, Biochemistry and Molecular Genetics

Huijue Lyu, Graduate Student, Yue Lab, Biochemistry and Molecular Genetics

The BMG Journal Club is an opportunity for the department to come together and have in-depth discussions about the current literature and the overall implications of new studies, enhancing everyone s knowledge of the field at large and about each other s research interests within the department; providing possible opportunities to collaborate as well. This is also an opportunity to practice vital presentation skills in front of a friendly audience.

Refreshments will be provided.

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Dec

06

Boren Scholarships & Boren Fellowships

Evanston - 12:00 PM - 1:00 PM

The Boren awards seek to help graduate and undergraduate students advance their proficiency in selected strategic languages through study abroad (undergrads) and langauge study & research (graduate students). At its core, Boren is a language program, thus competitive applicants will be serious students of a language not commonly taught in the United States. In addition, Boren funding comes from the US Government, thus they prize government service. All applicants must be thoughtful about how their career contributes to national security. Finally, Boren rewards long-duration study abroad. Most recipients will stay abroad for six months or more. Contact Stephen Hill in the Office of Fellowships for more information about the internal process. All Boren Awards applicants are encouraged to contact Stephen Hill for application guidance.

Register here: https://northwestern.zoom.us/j/96765925565

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Dec

07

Boren Scholarships & Boren Fellowships

Evanston - 12:00 PM - 1:00 PM

The Boren awards seek to help graduate and undergraduate students advance their proficiency in selected strategic languages through study abroad (undergrads) and langauge study & research (graduate students). At its core, Boren is a language program, thus competitive applicants will be serious students of a language not commonly taught in the United States. In addition, Boren funding comes from the US Government, thus they prize government service. All applicants must be thoughtful about how their career contributes to national security. Finally, Boren rewards long-duration study abroad. Most recipients will stay abroad for six months or more. Contact Stephen Hill in the Office of Fellowships for more information about the internal process. All Boren Awards applicants are encouraged to contact Stephen Hill for application guidance.

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Dec

07

M-I Dept. Seminar Series - "Mechanisms of Replication-Coupled DNA Repair"

Online - 12:00 PM - 1:00 PM

Title:

"Mechanisms of Replication-Coupled DNA Repair"

Kavi Mehta, PhD

Post-Doctoral Fellow, Lab of David Cortez, Department of Biochemistry

Vanderbilt University School of Medicine

Faculty Host: Laimonis Laimins, PhD

Topic:

The imperative of the cell is to finish replication. Cells experience tens of thousands of DNA lesions per day that must be repaired to ensure that genetic stability is maintained. The replication stress response is required to repair DNA lesions that arise due to both endogenous sources and exogenous, including pathogens and environmental genotoxins found in water, food, and industrial chemicals. My work focuses on understanding mechanisms by which cells protect the genome from genotoxic insult such as the cytidine deaminase APOBEC3A, and how repriming events by specialized polymerases downstream from a genetic lesion are regulated.

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Dec

08

Department Faculty Meeting

No Location - 12:00 PM - 1:00 PM

Cell & Developmental Biology Department Faculty Meeting

Meeting details disseminated via listserv. If you believe you missed an announcement, please email us at cdb@northwestern.edu.

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Dec

09

Immunology Journal Club

Chicago - 12:00 PM - 1:00 PM

Immunology topics presented

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Dec

14

M-I Dept. / John Karijolich, PhD

Chicago - 12:00 PM - 1:00 PM

Title TBA

John Karijolich, PhD

Associate Professor
Department of Pathology, Microbiology, and Immunology

Vanderbilt University Medical Center

Faculty Host: Eva Gottwein, PhD

Topic:

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Dec

15

CDB Seminar Series Presents: Maria Barna, PhD, Stanford University, CA

Online - 12:00 PM - 1:00 PM

CDB EXPERTS-IN-THE-FIELD SEMINAR PRESENTATION:

Maria Barna, PhD
Associate Professor of Genetics
Genetics Department, Stanford University, Stanford California

Wednesday, December 15, 2021

12:00-1:00 PM

via Zoom

Host: Dr. Luisa Iruela-Arispe
Stephen Walter Ranson Professor and Chair
Department of Cell and Developmental Biology

For more information please contact cdb@northwestern.edu
Zoom link sent via listserv. To subcribe to the CDB Seminar Series listserve please visit https://www.feinberg.northwestern.edu/sites/cdb/about/contact.html#listserv

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Dec

16

Immunology Journal Club

Chicago - 12:00 PM - 1:00 PM

Immunology topics presented

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Dec

17

CDB Year-end Holiday Celebration

No Location - 2:00 PM - 4:00 PM

Join the Cell & Developmental Biology Department faculty, trainees, and staff for a social gathering celebrating another year of great academic research.

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Dec

22

CDB Faculty Seminars Presents: Drs. Erica Davis and Farida Korobova

Online - 12:00 PM - 1:00 PM

CDB Faculty Seminars Presents:

Dr. Erica Davis
12:00-12:30pm

Dr. Farida Korobova
12:30-1:00pm

For more information please contact cdb@northwestern.edu
Zoom link sent via listserv. Click here to subcribe to the CDB Seminar Series listserv.

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Jan

04

M-I Dept. / Andy Zloza, MD, PhD

Chicago - 12:00 PM - 1:00 PM

Title TBA

Andy Zloza, MD, PhD

Assistant Professor
Department of Internal Medicine, Division of Hematology, Oncology and Cell Therapy, Rush Medical College, Rush University

Host: Immunology Graduate Students and Postdocs, Andrew Cogswell, Coordinator

Topic:

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Jan

05

Department Faculty Meeting

No Location - 12:00 PM - 1:00 PM

Cell & Developmental Biology Department Faculty Meeting

Meeting details disseminated via listserv. If you believe you missed an announcement, please email us at cdb@northwestern.edu.

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Jan

11

M-I Dept. / Bettina Cheung

Chicago - 12:00 PM - 1:00 PM

Title TBA

Bettina Cheung, Graduate Student, DGP, Lab of Alan Hauser MD, PhD

Faculty Host: Alan Hauser, MD, PHD

Topic:

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Jan

12

CDB Seminar Series Presents: Eric Baehrecke, Ph.D., University of Massachusetts Medical School, Worcester, MA

Online - 12:00 PM - 1:00 PM

CDB EXPERTS-IN-THE-FIELD SEMINAR PRESENTATION:

Eric Baehrecke, Ph.D.
Professor
Department of Molecular, Cell and Cancer Biology
University of Massachusetts Medical School, Worcester, MA

Wednesday, January 12, 2022

12:00-1:00 PM

via Zoom

Host: Dr. Congcong He
Assistant Professor
Department of Cell and Developmental Biology

For more information please contact cdb@northwestern.edu
Zoom link sent via listserv. To subcribe to the CDB Seminar Series listserve please visit https://www.feinberg.northwestern.edu/sites/cdb/about/contact.html#listserv

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Jan

18

M-I Dept. / Pamela Bjorkman, PhD

Online - 12:00 PM - 1:00 PM

Title TBA

Pamela BJorkman, PhD

David Baltimore Professor of Biology and Bioengineering; Executive Officer for Biology and Biological Engineering

Caltech Div. of Biology and Biological Engineering

Faculty Host: Pablo Penaloza-MacMaster, PhD

Topic:

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Jan

19

CDB Faculty Seminars Presents: Drs. Rex Chisholm and Elena Martinelli

Online - 12:00 PM - 1:00 PM

CDB Faculty Seminars Presents:

Dr. Rex Chisholm
12:00-12:30pm

Dr. Elena Martinelli
12:30-1:00pm

For more information please contact cdb@northwestern.edu
Zoom link sent via listserv. Click here to subcribe to the CDB Seminar Series listserv.

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Jan

20

Biochemistry and Molecular Genetics Departmental Seminar Series

Chicago - 10:00 AM - 11:00 AM

The Department of Biochemistry and Molecular Genetics presents:

TBD

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Jan

21

BMG Departmental Journal Club

Chicago - 1:00 PM - 2:00 PM

Presenter:

Zibo Zhao, Postdoctoral Scholar, Shilatifard Lab, Biochemistry and Molecular Genetics

The BMG Journal Club is an opportunity for the department to come together and have in-depth discussions about the current literature and the overall implications of new studies, enhancing everyone s knowledge of the field at large and about each other s research interests within the department; providing possible opportunities to collaborate as well. This is also an opportunity to practice vital presentation skills in front of a friendly audience.

Refreshments will be provided.

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