News and Announcements
Read the latest news from Simpson Querrey Institute for Epigenetics. The links below take you to articles where you can learn more about our faculty’s latest achievements, awards, and honors.
Epigenetic aging could serve as a promising biomarker for measuring long-term cardiovascular health and disease risk, according to a recent Northwestern Medicine study.
Two Northwestern Medicine studies are improving the understanding of epigenetic mechanisms in cancer development and progression, and identifying novel cancer driver genes that may help identify patients who will benefit from immunotherapy.
Northwestern Medicine investigators are advancing the understanding of two groups of transcription factors and their role in many neurodevelopmental diseases and cancers, which is essential for developing novel therapeutic approaches.
Northwestern Medicine investigators have discovered that oncogenes contain specific epigenetic markers called broad genic repression domains, which could help identify potential therapeutic targets for cancer treatment.
The DNA methylation landscape of regulatory T-cells is more complex than previously understood, according to a new Northwestern Medicine study.
A new $15 million gift from University trustees and supporters Louis A. Simpson and Kimberly K. Querrey will establish the Simpson Querrey Institute for Epigenetics at Northwestern University Feinberg School of Medicine, boosting the school’s current efforts to study the effects of environment on the regulation of gene expression.
Using mathematical modeling and optical imaging they developed themselves, a Northwestern University research team has discovered how chromatin folds at the single-cell level.
The Simpson Querrey Center for Epigenetics is connecting the Northwestern academic and medical community to integrate the study of epigenetics into science and clinical care.
Targeting cancer cells with a transcription elongation inhibitor delayed tumor progression in animal models, according to a recent Northwestern Medicine study.
Northwestern Medicine scientists are using a variety of innovative techniques to uncover the epigenetics of breast cancer, as seen in three recent studies.
Ali Shilatifard, PhD, has been appointed editor of Science Advances, an open-access journal published by the American Association for the Advancement of Science, which also publishes the journal Science.
A team of scientists has identified a key enhancer of Sox9 — a gene critical for male sex development — and demonstrated that deleting the enhancer results in male-to-female sex reversal in animal models.
Northwestern Medicine scientists have discovered an epigenetic imbalance that can lead to cancer, and used these findings to inhibit tumors in models.
Northwestern Medicine scientists have uncovered how DNA methylation triggers stem cells to transform into more specialized neuronal cells.
A new $10 million gift from University trustees and supporters Louis A. Simpson ’58 and Kimberly K. Querrey will create a center to study the effects of environment on the activation and expression of genes.
Ali Shilatifard, PhD, has been named the 15th recipient of the Martin E. and Gertrude G. Walder Award for Research Excellence, an honor given annually by the provost that recognizes excellence in research at Northwestern University.
Northwestern Medicine scientists explore research that has shown how the balanced activities of two protein families regulate gene expression during embryonic development and how mutations that tip this balance lead to cancer.
Lifang Hou, MD, PhD, chief of Cancer Epidemiology and Prevention in the Department of Preventive Medicine, has been named a member of a blue ribbon panel that will help inform the scientific direction of Vice President Joe Biden’s National Cancer Moonshot Initiative.
New insights into male germline development may help scientists better understand how external factors might have an effect on the germ cells of offspring in the future.
A new Northwestern Medicine study led by Navdeep Chandel, PhD, challenges the common understanding that energy production is mitochondria’s most important function.
Dan Foltz, ’02 PhD, Panagiotis Ntziachristos, PhD, and Marc Mendillo, PhD, have joined the Department of Biochemistry and Molecular Genetics.
“For the medical school, 2014 was a tremendous year,” said Eric G. Neilson, MD, vice president for medical affairs and Lewis Landsberg Dean. A collection of stories spotlight some of the notable moments from the past year.
Ali Shilatifard, PhD, Chair of Biochemistry and Molecular Genetics, was appointed to the senior editorial board of the scientific journal Science. In his new role, he will provide strategic advice and constructive feedback about the journal.
Ali Shilatifard, PhD, has been named the Robert Francis Furchgott Professor of Biochemistry and the Chairman of the Department of Biochemistry and Molecular Genetics.
Findings published by Northwestern Medicine scientists in Molecular Cell suggest that the upregulation of protein WDR5 may be crucial in prostate cancer development.
Joel Frader, MD, professor in pediatrics and medical humanities and bioethics, is being honored this fall by the American Academy of Pediatrics with the 2012 William G. Bartholome Award for Ethical Excellence.
Male Fetuses Most Vulnerable to Alcohol Exposure to alcohol in the womb doesn’t affect all fetuses equally. Why does one woman who drinks alcohol during pregnancy give birth to a child with physical, behavioral, or learning problems â known as fetal alcohol spectrum disorder â while another woman who also drinks has a child without [...]