News and Announcements
Read the latest news from Simpson Querrey Institute for Epigenetics. The links below take you to articles where you can learn more about our faculty’s latest achievements, awards, and honors.
Investigators discovered that the loss of the gene SLIT2 in circulating tumor cells regulates metastasis of prostate cancer tumors, according to a Northwestern Medicine study.
CRISPR pioneer and Nobel Laureate Jennifer Doudna, PhD is the recipient of the inaugural $250,000 Kimberly Prize in Biochemistry and Molecular Genetics.
Investigators have developed a new imaging technique that increases the detection and identification of proteoforms by four-fold when compared to current methods.
A Northwestern Medicine study has identified a molecular mechanism that helps regulate the progression of castration-resistant prostate cancer.
Bigger test panels are better for genetic testing in cardiomyopathy and heart arrhythmias, according to a recent Northwestern Medicine study.
Northwestern Medicine investigators have discovered novel mechanisms underlying transcription elongation, the process of synthesizing RNA from DNA.
An immune system kinase promotes tumor inflammation and progression, according to a study published in Nature Communications.
An epigenetic inhibitor increased immune system activity in patients with ovarian cancer.
Northwestern Medicine investigators have discovered novel mechanisms that regulate cellular stress response, according to findings published in the Proceedings of the National Academy of Sciences.
Bicarbonate ions are required for cell growth in some cancers, according to a Northwestern Medicine study.
An enzymatic modifier of messenger RNA has different functions depending on its location, according to a recent study.
A deep learning model has discovered genetic variations in cancer that are undetectable in traditional genome sequencing.
Recent studies have pointed to an expanded role for non-coding RNA, according to a Northwestern Medicine review.
Investigators have discovered a new method to determine whether individual genetic variants in the epilepsy-associated gene SZT2 cause the neurodevelopmental disorder, according to a Northwestern Medicine study.
A newly discovered inhibitor of a common cancer-causing protein operates selectively, reducing expression of genes that fuel rampant cell proliferation, and altering the epigenome, according to a recent study.
Northwestern Medicine investigators have discovered a potential therapeutic target for the most common type of pancreatic cancer, according to a study published in Developmental Cell.
A Northwestern Medicine study published in Nature Immunology has discovered that mitochondria control the activation of a specific protein complex linked to inflammation and the progression of chronic diseases.
A transcription factor associated with androgen receptor activity in prostate cancer has a newly discovered role in controlling lipid biosynthesis.
Northwestern Medicine scientists identified critical regulatory processes that govern differentiation in embryonic stem cells.
Isabella Salamone, an eighth-year student in the Driskill Graduate Program in Life Sciences, was lead author of a study published in the Journal of Clinical Investigation, which found that glucocorticoid steroids improved muscle performance through distinct, sex-specific molecular pathways.
Epigenetic markers of cognitive aging can predict outcomes on cognitive tests later in life, according to a recent Northwestern Medicine study.
A recent study published in Nature Genetics identified 10 new genetic regions associated with Brugada syndrome, a cardiac arrhythmia disorder.
Daniel Brat, MD, PhD, has been heavily involved in the process of moving molecular genetic biomarkers for glioma from the bench to the beside.
A well-established cancer cell transcription factor and its newly identified co-factor work together to drive cancer cell proliferation, according to a Northwestern Medicine study published in Science Advances.
Glucocorticoid steroids improved muscle performance through distinct, sex-specific mechanisms, according to a Northwestern Medicine study.
Northwestern Medicine scientists discovered functional links between dozens of potassium channel gene variants and neonatal epilepsy.
Northwestern Medicine investigators have discovered a novel mechanism that connects circadian rhythm-controlled cellular metabolism and regeneration with muscle repair after injury.
A genetic analysis indicates eosinophilic colitis is distinct from other eosinophilic gastrointestinal diseases and inflammatory bowel disease, according to a recent study.
Idiopathic dilated cardiomyopathy (DCM) was found to have a familial etiology in 30 percent of individuals diagnosed with DCM, and the overall risk for a family member of developing DCM was nearly 20 percent by the age of 80.