News and Announcements
Read the latest news from Simpson Querrey Institute for Epigenetics. The links below take you to articles where you can learn more about our faculty’s latest achievements, awards, and honors.
Northwestern Medicine investigators have shown that inhibiting a mutated gene can reduce seizure activity in adult-type diffuse gliomas, according to a study published in the Journal of Clinical Investigation.
Northwestern Medicine scientists have shed new light on how the deadliest form of thyroid cancer becomes more aggressive, according to research published in the Journal of Clinical Investigation.
Northwestern University scientists have discovered it is possible to isolate a tumor’s attack cells non-invasively from blood, rather than from tumors.
Jennifer A. Doudna, PhD, the Li Ka Shing Chancellor’s Chair and professor in the Departments of Chemistry and of Molecular and Cell Biology at the University of California, Berkeley, delivered the inaugural Kimberly Prize in Biochemistry and Molecular Genetics Lecture to Feinberg faculty, staff and students on Tuesday, April 4.
Two therapeutic drugs benefited mice with non-small cell lung cancer, potentially paving the way for clinical trials in humans.
The fast motor function of prestin, a protein found in the inner ear, is essential for mammalian hearing, according to a Northwestern Medicine study published in the Proceedings of the National Academy of Sciences.
Northwestern Medicine scientists have identified a gene that plays a role in cellular responses to molecular stressors, such as DNA damage and nutrient scarcity.
Scientists have identified new genes linked to heart failure, according to a study published in Nature Communications.
Northwestern Medicine scientists have identified pathogenic variants in two genes linked to microcephaly and other neurodevelopmental disorders in children, according to a recent study published in Nature Communications.
Genetic testing in epilepsy patients can inform treatment and lead to better outcomes in many cases, according to a study published in JAMA Neurology.
Northwestern Medicine scientists have identified a gene that is responsible for activating an aggressive subtype of small-cell lung cancer for which there is no current effective treatment.
Patients with acute myeloid leukemia show large-scale genomic mutations and altered DNA folding patterns that could help identify potential therapeutic targets, according to a Northwestern Medicine study published in Nature.
- Center for Genetic Medicine Announces New Director for Transgenic and Targeted Mutagenesis Laboratory10.12.2022
Styliani (Stella) Markoulaki, PhD, has been named the new director of the Transgenic and Targeted Mutagenesis Laboratory.
An epigenetics drug currently being used for the treatment of blood cancers and rare sarcomas can stop the growth of bladder cancer by activating the immune system, according to a new study.
Investigators discovered that the loss of the gene SLIT2 in circulating tumor cells regulates metastasis of prostate cancer tumors, according to a Northwestern Medicine study.
CRISPR pioneer and Nobel Laureate Jennifer Doudna, PhD is the recipient of the inaugural $250,000 Kimberly Prize in Biochemistry and Molecular Genetics.
Investigators have developed a new imaging technique that increases the detection and identification of proteoforms by four-fold when compared to current methods.
A Northwestern Medicine study has identified a molecular mechanism that helps regulate the progression of castration-resistant prostate cancer.
Bigger test panels are better for genetic testing in cardiomyopathy and heart arrhythmias, according to a recent Northwestern Medicine study.
Northwestern Medicine investigators have discovered novel mechanisms underlying transcription elongation, the process of synthesizing RNA from DNA.
An immune system kinase promotes tumor inflammation and progression, according to a study published in Nature Communications.
An epigenetic inhibitor increased immune system activity in patients with ovarian cancer.
Northwestern Medicine investigators have discovered novel mechanisms that regulate cellular stress response, according to findings published in the Proceedings of the National Academy of Sciences.
Bicarbonate ions are required for cell growth in some cancers, according to a Northwestern Medicine study.
An enzymatic modifier of messenger RNA has different functions depending on its location, according to a recent study.
A deep learning model has discovered genetic variations in cancer that are undetectable in traditional genome sequencing.
Recent studies have pointed to an expanded role for non-coding RNA, according to a Northwestern Medicine review.
Investigators have discovered a new method to determine whether individual genetic variants in the epilepsy-associated gene SZT2 cause the neurodevelopmental disorder, according to a Northwestern Medicine study.
A newly discovered inhibitor of a common cancer-causing protein operates selectively, reducing expression of genes that fuel rampant cell proliferation, and altering the epigenome, according to a recent study.