News and Announcements
Read the latest news from Simpson Querrey Institute for Epigenetics. The links below take you to articles where you can learn more about our faculty’s latest achievements, awards, and honors.
- 01.18.2024
A multidisciplinary team of investigators has developed a first-of-its-kind interactive 3D spatial approach that reveals new therapeutic targets and provides a comprehensive three-dimensional view of glioblastoma tumors, detailed in a recent study published in Cell.
- 01.16.2024
Investigators led by Elizabeth McNally, MD, PhD, the Elizabeth J. Ward Professor of Genetic Medicine and director of the Center for Genetic Medicine, have discovered previously unknown protein interactions in the heart’s atrium that are critical for normal heart function, according to findings published in the Proceedings of the National Academy of Sciences.
- 01.05.2024
Some strains of an antibiotic-resistant bacteria may not turn out to be as aggressive as previously thought, according to a Northwestern Medicine study recently published in Nature Communications.
- 12.20.2023
Northwestern Medicine investigators have successfully localized novel molecular mechanisms behind a genetic mutation found in a wide range of cancers, which could serve as a biomarker for improving patient stratification and treatment, according to findings published in Proceedings of the National Academy of Sciences.
- 12.05.2023
Northwestern University Feinberg School of Medicine and the Simpson Querrey Institute for Epigenetics announced today that renowned biochemist Craig M. Crews, PhD, who pioneered the pharmaceutical field of targeted protein degradation, has been named the winner of the annual $250,000 Kimberly Prize in Biochemistry and Molecular Genetics.
- 11.22.2023
Investigators from the laboratory of Ali Shilatifard, PhD, have discovered a new repeat gene cluster sequence that is exclusively expressed in humans and non-human primates, according to findings published in Science Advances.
- 11.16.2023
A new molecular technology capable of binding to mRNA and regulating gene expression may offer a new avenue for treating diseases caused by insufficient protein levels, according to a study published in Nature Communications.
- 11.09.2023
Investigators led by Neil Kelleher, PhD, have developed an automated technique for imaging proteoforms in ovarian cancer, according to results published in Nature Communications.
- 11.02.2023
In a recent article published in Molecular Cell, the laboratory of Ali Shilatifard, PhD, provided a comprehensive overview of the current understanding of the elongation stage of DNA transcription and how its dysregulation is associated with developmental defects, disease and aging.
- 09.26.2023
A multi-institutional team of investigators including Northwestern University scientists has received $45 million to fast-track the development of a first-of-its-kind implant to sense and treat cancer.
- 09.20.2023
Northwestern Medicine investigators have discovered how the PD-1 protein controls essential metabolic processes in tumor cells to promote cancer growth in T-cell non-Hodgkin lymphomas, according to a study published in Nature Cancer.
- 09.11.2023
Northwestern Medicine scientists have developed an engineered probiotic capable of detecting inflammatory bowel disease, according to a study published in the Proceedings of the National Academy of Sciences.
- 09.06.2023
Naturally occurring variations near the human gene CHD1L may be linked to lower HIV-1 viral load in people of African ancestry, according to a new international, multicenter study published in Nature.
- 09.05.2023
Northwestern Medicine scientists have revealed how a gene considered essential for histone modification regulates skin development, according to a recent study published in Nature Communications.
- 08.25.2023
An experimental drug targeting a genetic variant linked to Parkinson’s disease had no effect on patients, according to the results of a new clinical trial published in The Lancet Neurology.
- 08.17.2023
Northwestern Medicine investigators have uncovered how the ALS-associated gene NEK1 disrupts neuronal function in a new study published in Science Advances.
- 08.16.2023
More cases of children born with abnormal brain development may have genetic explanations than previously thought, according to a recent study published in JAMA Neurology.
- 08.15.2023
Northwestern Medicine investigators led by Ruli Gao, PhD, have developed a novel genetic sequencing tool that accelerates sequencing analysis of same-cell genotypes and phenotypes in tumors, as detailed in a study published in Nature Communications.
- 08.11.2023
Northwestern Medicine scientists have developed a new cellular model of uterine fibroids that stem from a common genetic mutation, which will accelerate further research and treatment development, according to findings published in Nature Communications.
- 08.10.2023
Navdeep Chandel, PhD, the David W. Cugell, MD, Professor of Medicine in the Division of Pulmonary and Critical Care and of Biochemistry and Molecular Genetics, has been named a recipient of the 2023 Lurie Prize in Biomedical Sciences by the Foundation for the National Institutes of Health.
- 08.09.2023
Northwestern University is accepting nominations for its $250,000 Kimberly Prize in Biochemistry and Molecular Genetics. The annual prize will be awarded in 2024.
- 08.09.2023
Northwestern Medicine investigators have discovered that mitochondria regulate essential cellular signaling for the development of epithelial cells in the lungs, cells which are crucial for the exchange of oxygen and carbon dioxide to avoid respiratory failure, according to findings published in Nature.
- 07.26.2023
Investigators led by Shana Kelley, PhD, have developed a novel approach for identifying sequences of artificial DNA with differing levels of binding to other small molecules, which could improve diagnostic monitoring for patients with chronic diseases.
- 07.18.2023
Recent and long-term marijuana use is linked to changes in the human genome, a new Northwestern Medicine study published in Molecular Psychiatry has found.
- 07.12.2023
Northwestern Medicine investigators have discovered a novel protein region that regulates DNA transcription elongation, suggesting a new therapeutic target for treating cancers and developmental disorders, according to findings published in Molecular Cell.
- 06.22.2023
Northwestern Medicine scientists have identified a novel vulnerability in a subset of genes commonly mutated in cancer, according to a study recently published in The Journal of Clinical Investigation.
- 05.31.2023
Northwestern Medicine investigators have shown that inhibiting a mutated gene can reduce seizure activity in adult-type diffuse gliomas, according to a study published in the Journal of Clinical Investigation.
- 05.19.2023
Northwestern Medicine scientists have shed new light on how the deadliest form of thyroid cancer becomes more aggressive, according to research published in the Journal of Clinical Investigation.
- 04.10.2023
Northwestern University scientists have discovered it is possible to isolate a tumor’s attack cells non-invasively from blood, rather than from tumors.