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Recent Publications
View the most recent publications from Feinberg facutly, updated daily.High-Impact Archive
Explore curated high-impact publication lists from previous years (2013-2021).2022 High-Impact Research
Below, browse our a curated list of faculty work from this year that was published in major academic publications.
- Amici DR, Ansel DJ, Metz KA, Smith RS, Phoumyvong CM, Gayatri S, Chamera T, Edwards SL, O'Hara BP, Srivastava S, Brockway S, Takagishi SR, Cho BK, Goo YA, Kelleher NL, Ben-Sahra I, Foltz DR, Li J, Mendillo ML. C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways. Proceedings of the National Academy of Sciences of the United States of America. 2022;119(27):e2111262119.
- Chen S, Xie P, Cowan M, Huang H, Cardenas H, Keathley R, Tanner EJ, Fleming GF, Moroney JW, Pant A, Akasha AM, Davuluri RV, Kocherginsky M, Zhang B, Matei D. Epigenetic priming enhances antitumor immunity in platinum-resistant ovarian cancer. Journal of Clinical Investigation. 2022;132(14)
- Coelho DR, Palma FR, Paviani V, He C, Danes JM, Huang Y, Calado JCP, Hart PC, Furdui CM, Poole LB, Schipma MJ, Bonini MG. Nuclear-localized, iron-bound superoxide dismutase-2 antagonizes epithelial lineage programs to promote stemness of breast cancer cells via a histone demethylase activity. Proceedings of the National Academy of Sciences of the United States of America. 2022;119(29):e2110348119.
- Halasa NB, Olson SM, Staat MA, Newhams MM, Price AM, Pannaraj PS, Boom JA, Sahni LC, Chiotos K, Cameron MA, Bline KE, Hobbs CV, Maddux AB, Coates BM, Michelson KN, Heidemann SM, Irby K, Nofziger RA, Mack EH, Smallcomb L, Schwartz SP, Walker TC, Gertz SJ, Schuster JE, Kamidani S, Tarquinio KM, Bhumbra SS, Maamari M, Hume JR, Crandall H, Levy ER, Zinter MS, Bradford TT, Flori HR, Cullimore ML, Kong MCL, Cvijanovich NZ, Gilboa SM, Polen KN, Campbell AP, Randolph AG, Patel MM, Overcoming Covid I. Maternal Vaccination and Risk of Hospitalization for Covid-19 among Infants. New England Journal of Medicine. 2022;387(2):109-119.
- Khan A, Turchin MC, Patki A, Srinivasasainagendra V, Shang N, Nadukuru R, Jones AC, Malolepsza E, Dikilitas O, Kullo IJ, Schaid DJ, Karlson E, Ge T, Meigs JB, Smoller JW, Lange C, Crosslin DR, Jarvik GP, Bhatraju PK, Hellwege JN, Chandler P, Torvik LR, Fedotov A, Liu C, Kachulis C, Lennon N, Abul-Husn NS, Cho JH, Ionita-Laza I, Gharavi AG, Chung WK, Hripcsak G, Weng C, Nadkarni G, Irvin MR, Tiwari HK, Kenny EE, Limdi NA, Kiryluk K. Genome-wide polygenic score to predict chronic kidney disease across ancestries. Nature Medicine. 2022;28(7):1412-1420.
- Lee HJ, Hou Y, Maeng JH, Shah NM, Chen Y, Lawson HA, Yang H, Yue F, Wang T. Epigenomic analysis reveals prevalent contribution of transposable elements to cis-regulatory elements, tissue-specific expression, and alternative promoters in zebrafish. Genome Research. 2022;32(7):1424-1436.
- Liedmann S, Liu XY, Guy CS, Crawford JC, Rodriguez DA, Kuzuoglu-Ozturk D, Guo A, Verbist KC, Temirov J, Chen MJ, Ruggero D, Zhang H, Thomas PG, Green DR. Localization of a TORC1-eIF4F translation complex during CD8(+) T cell activation drives divergent cell fate. Molecular Cell. 2022;82(13):2401.
- Lin H, Geurts F, Hassler L, Batlle D, Colafella KMM, Denton KM, Zhuo JL, Li XC, Ramkumar N, Koizumi M, Matsusaka T, Nishiyama A, Hoogduijn MJ, Hoorn EJ, Danser AHJ. Kidney Angiotensin in Cardiovascular Disease: Formation and Drug Targeting. Review. Pharmacological Reviews. 2022;74(3):462-505.
- Liu JF, Brady MF, Matulonis UA, Miller A, Kohn EC, Swisher EM, Cella D, Tew WP, Cloven NG, Muller CY, Bender DP, Moore RG, Michelin DP, Waggoner SE, Geller MA, Fujiwara K, D'Andre SD, Carney M, Secord AA, Moxley KM, Bookman MA. Olaparib With or Without Cediranib Versus Platinum-Based Chemotherapy in Recurrent Platinum-Sensitive Ovarian Cancer (NRG-GY004): A Randomized, Open-Label, Phase III Trial. Journal of Clinical Oncology. 2022;40(19):2138.
- Lloyd SM, Leon DB, Brady MO, Rodriguez D, McReynolds MP, Kweon J, Neely AE, Blumensaadt LA, Ho PJ, Bao X. CDK9 activity switch associated with AFF1 and HEXIM1 controls differentiation initiation from epidermal progenitors. Nature Communications. 2022;13(1):4408.
- Nguyen TK, Yadav S, Truong TA, Han MD, Barton M, Leitch M, Guzman P, Dinh T, Ashok A, Vu H, Van D, Haasmann D, Chen L, Park Y, Do TN, Yamauchi Y, Rogers JA, Nguyen NT, Phan HP. Integrated, Transparent Silicon Carbide Electronics and Sensors for Radio Frequency Biomedical Therapy. ACS Nano. 2022;16(7):10890-10903.
- Niec RE, Chu T, Schernthanner M, Gur-Cohen S, Hidalgo L, Pasolli HA, Luckett KA, Wang Z, Bhalla SR, Cambuli F, Kataru RP, Ganesh K, Mehrara BJ, Pe'er D, Fuchs E. Lymphatics act as a signaling hub to regulate intestinal stem cell activity. Cell Stem Cell. 2022;29(7):1067-1082.e18
- Oyer RA, Hurley P, Boehmer L, Bruinooge SS, Levit K, Barrett N, Benson AI, Bernick LA, Byatt L, Charlot M, Crews J, DeLeon K, Fashoyin-Aje L, Garrett-Mayer E, Gralow JR, Green S, Guerra CE, Hamroun L, Hardy CM, Hempstead B, Jeames S, Mann M, Matin K, McCaskill-Stevens W, Merrill J, Nowakowski GS, Patel MI, Pressman A, Ramirez AG, Segura J, Segarra-Vasquez B, Williams JH, Williams JE, Winkfield KM, Yang ES, Zwicker V, Pierce LJ. Increasing Racial and Ethnic Diversity in Cancer Clinical Trials: An American Society of Clinical Oncology and Association of Community Cancer Centers Joint Research Statement. Journal of Clinical Oncology. 2022;40(19):2163.
- Pandit JA, Radin JM, Quer G, Topol EJ. Smartphone apps in the COVID-19 pandemic. Nature Biotechnology. 2022;40(7):1013-1022.
- Post WS, Watson KE, Hansen S, Folsom AR, Szklo M, Shea S, Barr RG, Burke G, Bertoni AG, Allen N, Pankow JS, Lima JAC, Rotter JI, Kaufman JD, Johnson WC, Kronmal RA, Diez-Roux AV, McClelland RL. Racial and Ethnic Differences in All-Cause and Cardiovascular Disease Mortality: The MESA Study. Circulation. 2022;146(3):229-239.
- Querrey M, Chiu S, Lecuona E, Wu Q, Sun H, Anderson M, Kelly M, Ravi S, Misharin AV, Kreisel D, Bharat A, Budinger GRS. CD11b suppresses TLR activation of nonclassical monocytes to reduce primary graft dysfunction after lung transplantation. Journal of Clinical Investigation. 2022;132(14).
- Reeder JT, Xie Z, Yang Q, Seo MH, Yan Y, Deng Y, Jinkins KR, Krishnan SR, Liu C, McKay S, Patnaude E, Johnson A, Zhao Z, Kim MJ, Xu Y, Huang I, Avila R, Felicelli C, Ray E, Guo X, Ray WZ, Huang Y, MacEwan MR, Rogers JA. Soft, bioresorbable coolers for reversible conduction block of peripheral nerves. Science. 2022;377(6601):109-115.
- Schwandt H, Currie J, von Wachter T, Kowarski J, Chapman D, Woolf SH. Changes in the Relationship Between Income and Life Expectancy Before and During the COVID-19 Pandemic, California, 2015-2021. JAMA. 2022;328(4):360-366.
- Shah NS, Ning HY, Petito LC, Kershaw KN, Bancks MP, Reis JP, Rana JS, Sidney S, Jacobs DR, Kiefe CI, Carnethon MR, Lloyd-Jones DM, Allen NB, Khan SS. Associations of Clinical and Social Risk Factors With Racial Differences in Premature Cardiovascular Disease. Circulation. 2022;146(3):201-210.
- Sies H, Belousov VV, Chandel NS, Davies MJ, Jones DP, Mann GE, Murphy MP, Yamamoto M, Winterbourn C. Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology. Nature Reviews Molecular Cell Biology. 2022;23(7):499-515.
- Wienbar S, Schwartz GW. Differences in spike generation instead of synaptic inputs determine the feature selectivity of two retinal cell types. Neuron. 2022;110(13):2110-2123.e4.
- Woods-Hill CZ, Colantuoni EA, Koontz DW, Voskertchian A, Xie A, Thurm C, Miller MR, Fackler JC, Milstone AM, Agulnik A, Albert JE, Auth MJ, Bradley E, Clayton JA, Coffin SE, Dallefeld S, Ezetendu CP, Fainberg NA, Flaherty BF, Foster CB, Hauger SB, Hong SJ, Hysmith ND, Kirby AL, Kociolek LK, Larsen GY, Lin JC, Linam WM, Newland JG, Nolt D, Priebe GP, Sandora TJ, Schwenk HT, Smith CM, Steffen KM, Tadphale SD, Toltzis P, Wolf J, Zerr DM. Association of Diagnostic Stewardship for Blood Cultures in Critically Ill Children With Culture Rates, Antibiotic Use, and Patient Outcomes: Results of the Bright STAR Collaborative. JAMA Pediatrics. 2022;176(7):690-698.
- Yang JM, Ren YJ, Kumar A, Xiong XF, Das JK, Peng HY, Wang LQ, Ren XC, Zhang Y, Ji C, Cheng Y, Zhang L, Alaniz RC, de Figueiredo P, Fang DY, Zhou HW, Liu XQ, Wang JL, Song JX. NAC1 modulates autoimmunity by suppressing regulatory T cell-mediated tolerance. Science Advances. 2022;8(26):13.
- Zhang WL, Callmann CE, Meckes B, Mirkin CA. Tumor-Associated Enzyme-Activatable Spherical Nucleic Acids. ACS Nano. 2022;16(7):10931-10942.
- Zheng YA, Joyce B, Hwang SJ, Ma JT, Liu L, Allen N, Krefman A, Wang J, Gao T, Nannini D, Zhang HX, Jacobs DR, Gross M, Fornage M, Lewis CE, Schreiner PJ, Sidney S, Chen DQ, Greenland P, Levy D, Hou LF, Lloyd-Jones D. Association of Cardiovascular Health Through Young Adulthood With Genome-Wide DNA Methylation Patterns in Midlife: The CARDIA Study. Circulation. 2022;146(2):94-109.
- Basch E, Schrag D, Henson S, Jansen J, Ginos B, Stover AM, Carr P, Spears PA, Jonsson M, Deal AM, Bennett AV, Thanarajasingam G, Rogak LJ, Reeve BB, Snyder C, Bruner D, Cella D, Kottschade LA, Perlmutter J, Geoghegan C, Samuel-Ryals CA, Given B, Mazza GL, Miller R, Strasser JF, Zylla DM, Weiss A, Blinder VS, Dueck AC. Effect of Electronic Symptom Monitoring on Patient-Reported Outcomes Among Patients With Metastatic Cancer: A Randomized Clinical Trial. JAMA-Journal of the American Medical Association. 2022;327(24):2413-2422.
- Capano LS, Sato C, Ficulle E, Yu AA, Horie K, Kwon JS, Burbach KF, Barthelemy NR, Fox SG, Karch CM, Bateman RJ, Houlden H, Morimoto RI, Holtzman DM, Duff KE, Yoo AS. Recapitulation of endogenous 4R tau expression and formation of insoluble tau in directly reprogrammed human neurons. Cell Stem Cell. 2022;29(6):918.
- Chen YY, O'Halloran TV. A zinc chaperone mediates the flow of an inorganic commodity to an important cellular client. Cell. 2022;185(12):2013-2015.
- D'Haens GR, Sandborn WJ, Loftus EV, Jr., Hanauer SB, Schreiber S, Peyrin-Biroulet L, Panaccione R, Panés J, Baert F, Colombel JF, Ferrante M, Louis E, Armuzzi A, Zhou Q, Goteti VS, Mostafa NM, Doan TT, Petersson J, Finney-Hayward T, Song AP, Robinson AM, Danese S. Higher vs Standard Adalimumab Induction Dosing Regimens and Two Maintenance Strategies: Randomized SERENE CD Trial Results. Gastroenterology. 2022;162(7):1876-1890.
- Emerson DJ, Zhao PYA, Cook AL, Barnett RJ, Klein KN, Saulebekova D, Ge CM, Zhou LD, Simandi Z, Minsk MK, Titus KR, Wang WT, Gong WF, Zhang D, Yang LY, Venev SV, Gibcus JH, Yang HB, Sasaki T, Kanemaki MT, Yue F, Dekker J, Chen CL, Gilbert DM, Phillips-Cremins JE. Cohesin-mediated loop anchors confine the locations of human replication origins. Nature. 2022;606(7915):812.
- Gangopadhyay A, Devi S, Tenguria S, Carriere J, Nguyen H, Jager E, Khatri H, Chu LH, Ratsimandresy RA, Dorfleutner A, Stehlik C. NLRP3 licenses NLRP11 for inflammasome activation in human macrophages. Nature Immunology. 2022;23(6):892.
- Gettler LT, Rosenbaum S, Kuo PX, Sarma MS, Bechayda SA, McDade TW, Kuzawa CW. Evidence for an adolescent sensitive period to family experiences influencing adult male testosterone production. Proceedings of the National Academy of Sciences of the United States of America. 2022;119(23):e2202874119.
- Gleixner AM, Verdone BM, Otte CG, Anderson EN, Ramesh N, Shapiro OR, Gale JR, Mauna JC, Mann JR, Copley KE, Daley EL, Ortega JA, Cicardi ME, Kiskinis E, Kofler J, Pandey UB, Trotti D, Donnelly CJ. NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility. Nature Communications. 2022;13(1):17.
- Ibrahim SA, Reynolds KA, Poon E, Alam M. The evidence base for US joint commission hospital accreditation standards: cross sectional study. BMJ. 2022;377:e063064.
- Jinkins KR, Li SP, Arafa H, Jeong H, Lee YJ, Wu CS, Campisi E, Ni XC, Cho D, Huang YG, Rogers JA. Thermally switchable, crystallizable oil and silicone composite adhesives for skin-interfaced wearable devices. Science Advances. 2022;8(23):11.
- Joutsa J, Moussawi K, Siddiqi SH, Abdolahi A, Drew W, Cohen AL, Ross TJ, Deshpande HU, Wang HZ, Bruss J, Stein EA, Volkow ND, Grafman JH, van Wijngaarden E, Boes AD, Fox MD. Brain lesions disrupting addiction map to a common human brain circuit. Nature Medicine. 2022;28(6):1249.
- Kim MH, Schwartz GL, White JS, Glymour MM, Reardon SF, Kershaw KN, Gomez SL, Collin DF, Inamdar PP, Wang G, Hamad R. School racial segregation and long-term cardiovascular health among Black adults in the US: A quasi-experimental study. PLoS Medicine. 2022;19(6):e1004031.
- Kurniansyah N, Goodman MO, Kelly TN, Elfassy T, Wiggins KL, Bis JC, Guo XQ, Palmas W, Taylor KD, Lin HJ, Haessler J, Gao Y, Shimbo D, Smith JA, Yu B, Feofanova EV, Smit RAJ, Wang Z, Hwang SJ, Liu SM, Wassertheil-Smoller S, Manson JE, Lloyd-Jones DM, Rich SS, Loos RJF, Redline S, Correa A, Kooperberg C, Fornage M, Kaplan RC, Psaty BM, Rotter JI, Arnett DK, Morrison AC, Franceschini N, Levy D, Sofer T, Precision NTO. A multi-ethnic polygenic risk score is associated with hypertension prevalence and progression throughout adulthood. Nature Communications. 2022;13(1):13.
- Mangione CM, Barry MJ, Nicholson WK, Cabana M, Chelmow D, Coker TR, Davis EM, Donahue KE, Epling JW, Jaen CR, Krist AH, Kubik M, Li L, Ogedegbe G, Pbert L, Ruiz JM, Simon MA, Stevermer J, Wong JB, Force USPST. Screening for Impaired Visual Acuity in Older Adults US Preventive Services Task Force Recommendation Statement. JAMA-Journal of the American Medical Association. 2022;327(21):2123-2128.
- Morgan M, Shiekhattar R, Shilatifard A, Lauberth SM. It's a DoG-eat-DoG world-altered transcriptional mechanisms drive downstream-of-gene (DoG) transcript production. Molecular Cell. 2022;82(11):1981-1991.
- Motzer R, Porta C, Alekseev B, Rha SY, Choueiri TK, Mendez-Vidal MJ, Hong SH, Kapoor A, Goh JC, Eto M, Bennett L, Wang J, Pan JJ, Saretsky TL, Perini RF, He CS, Mody K, Cella D. Health-related quality-of-life outcomes in patients with advanced renal cell carcinoma treated with lenvatinib plus pembrolizumab or everolimus versus sunitinib (CLEAR): a randomised, phase 3 study. Lancet Oncology. 2022;23(6):768-780.
- Ozturk H, Cingoz H, Tufan T, Yang J, Adair SJ, Tummala KS, Kuscu C, Kinali M, Comertpay G, Nagdas S, Goudreau BJ, Luleyap HU, Bingul Y, Ware TB, Hwang WL, Hsu KL, Kashatus DF, Ting DT, Chandel NS, Bardeesy N, Bauer TW, Adli M. ISL2 is a putative tumor suppressor whose epigenetic silencing reprograms the metabolism of pancreatic cancer. Developmental Cell. 2022;57(11):1331-1346.e9.
- Sands BE, Irving PM, Hoops T, Izanec JL, Gao LL, Gasink C, Greenspan A, Allez M, Danese S, Hanauer SB, Jairath V, Kuehbacher T, Lewis JD, Loftus EV, Jr., Mihaly E, Panaccione R, Scherl E, Shchukina OB, Sandborn WJ. Ustekinumab versus adalimumab for induction and maintenance therapy in biologic-naive patients with moderately to severely active Crohn's disease: a multicentre, randomised, double-blind, parallel-group, phase 3b trial. Lancet. 2022;399(10342):2200-2211.
- Tiek DM, Erdogdu B, Razaghi R, Jin L, Sadowski N, Alamillo-Ferrer C, Hogg JR, Haddad BR, Drewry DH, Wells CI, Pickett JE, Song X, Goenka A, Hu B, Goldlust SA, Zuercher WJ, Pertea M, Timp W, Cheng SY, Riggins RB. Temozolomide-induced guanine mutations create exploitable vulnerabilities of guanine-rich DNA and RNA regions in drug-resistant gliomas. Science Advances. 2022;8(25):14.
- Wang XT, Luan Y, Yue F. EagleC: A deep-learning framework for detecting a full range of structural variations from bulk and single-cell contact maps. Science Advances. 2022;8(24):14.
- Wenger NK, Lloyd-Jones DM, Elkind MSV, Fonarow GC, Warner JJ, Alger HM, Cheng S, Kinzy C, Hall JL, Roger VL, Amer Heart A. Call to Action for Cardiovascular Disease in Women: Epidemiology, Awareness, Access, and Delivery of Equitable Health Care: A Presidential Advisory From the American Heart Association. Circulation. 2022;145(23):E1059-E1071.
- Won JH, Choi JS, Jun JI. CCN1 interacts with integrins to regulate intestinal stem cell proliferation and differentiation. Nature Communications. 2022;13(1):15.
- Zeng CJ, Bastarache LA, Tao R, Venner E, Hebbring S, Andujar JD, Bland ST, Crosslin DR, Pratap S, Cooley A, Pacheco JA, Christensen KD, Perez E, Zawatsky CLB, Witkowski L, Zouk H, Weng CH, Leppig KA, Sleiman PMA, Hakonarson H, Williams MS, Luo Y, Jarvik GP, Green RC, Chung WK, Gharavi AG, Lennon NJ, Rehm HL, Gibbs RA, Peterson JF, Roden DM, Wiesner GL, Denny JC. Association of Pathogenic Variants in Hereditary Cancer Genes With Multiple Diseases. JAMA Oncology. 2022;8(6):835-844.
- Zhang GT, Roberto NM, Lee D, Hahnel SR, Andersen EC. The impact of species-wide gene expression variation on Caenorhabditis elegans complex traits. Nature Communications. 2022;13(1):13.
- Zhang XY, Lucas AM, Veturi Y, Drivas TG, Bone WP, Verma A, Chung WK, Crosslin D, Denny JC, Hebbring S, Jarvik GP, Kullo I, Larson EB, Rasmussen-Torvik LJ, Schaid DJ, Smoller JW, Stanaway IB, Wei WQ, Weng CH, Ritchie MD. Large-scale genomic analyses reveal insights into pleiotropy across circulatory system diseases and nervous system disorders. Nature Communications. 2022;13(1):12.
- Billingham LK, Stoolman JS, Vasan K, Rodriguez AE, Poor TA, Szibor M, Jacobs HT, Reczek CR, Rashidi A, Zhang P, Miska J, Chandel NS. Mitochondrial electron transport chain is necessary for NLRP3 inflammasome activation. Nature Immunology. 2022;23(5):692.
- Borlaug BA, Blair J, Bergmann MW, Bugger H, Burkhoff D, Bruch L, Celermajer DS, Claggett B, Cleland JGF, Cutlip DE, Dauber I, Eicher JC, Gao Q, Gorter TM, Gustafsson F, Hayward C, van der Heyden J, Hasenfuss G, Hummel SL, Kaye DM, Komtebedde J, Massaro JM, Mazurek JA, McKenzie S, Mehta SR, Petrie MC, Post MC, Nair A, Rieth A, Silvestry FE, Solomon SD, Trochu JN, Van Veldhuisen DJ, Westenfeld R, Leon MB, Shah SJJ. Latent Pulmonary Vascular Disease May Alter the Response to Therapeutic Atrial Shunt Device in Heart Failure. Circulation. 2022;145(21):1592-1604.
- Cenik BK, Sze CC, Ryan CA, Das S, Cao K, Douillet D, Rendleman EJ, Zha D, Khan NH, Bartom E, Shilatifard A. A synthetic lethality screen reveals ING5 as a genetic dependency of catalytically dead Set1A/COMPASS in mouse embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 2022;119(19):e2118385119.
- Choi YS, Jeong H, Yin RT, Avila R, Pfenniger A, Yoo J, Lee JY, Tzavelis A, Lee YJ, Chen SW, Knight HS, Kim S, Ahn HY, Wickerson G, Vázquez-Guardado A, Higbee-Dempsey E, Russo BA, Napolitano MA, Holleran TJ, Razzak LA, Miniovich AN, Lee G, Geist B, Kim B, Han S, Brennan JA, Aras K, Kwak SS, Kim J, Waters EA, Yang X, Burrell A, San Chun K, Liu C, Wu C, Rwei AY, Spann AN, Banks A, Johnson D, Zhang ZJ, Haney CR, Jin SH, Sahakian AV, Huang Y, Trachiotis GD, Knight BP, Arora RK, Efimov IR, Rogers JA. A transient, closed-loop network of wireless, body-integrated devices for autonomous electrotherapy. Science. 2022;376(6596):1006-1012.
- Choudhury A, Magill ST, Eaton CD, Prager BC, Chen WC, Cady MA, Seo K, Lucas CHG, Casey-Clyde TJ, Vasudevan HN, Liu SJ, Villanueva-Meyer JE, Lam TC, Pu JKS, Li LF, Leung GKK, Swaney DL, Zhang MY, Chan JW, Qiu ZX, Martin MV, Susko MS, Braunstein SE, Bush NAO, Schulte JD, Butowski N, Sneed PK, Berger MS, Krogan NJ, Perry A, Phillips JJ, Solomon DA, Costello JF, McDermott MW, Rich JN, Raleigh DR. Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities. Nature Genetics. May 2022;54(5):649.
- Cruz Rivera S, Aiyegbusi OL, Ives J, Draper H, Mercieca-Bebber R, Ells C, Hunn A, Scott JA, Fernandez CV, Dickens AP, Anderson N, Bhatnagar V, Bottomley A, Campbell L, Collett C, Collis P, Craig K, Davies H, Golub R, Gosden L, Gnanasakthy A, Haf Davies E, von Hildebrand M, Lord JM, Mahendraratnam N, Miyaji T, Morel T, Monteiro J, Zwisler AO, Peipert JD, Roydhouse J, Stover AM, Wilson R, Yap C, Calvert MJ. Ethical Considerations for the Inclusion of Patient-Reported Outcomes in Clinical Research: The PRO Ethics Guidelines. JAMA-Journal of the American Medical Association. 2022;327(19):1910-1919.
- Garcia-Anoveros J, Clancy JC, Foo CZ, Garcia-Gomez I, Zhou YJ, Homma K, Cheatham MA, Duggan A. Tbx2 is a master regulator of inner versus outer hair cell differentiation. Article. Nature. 2022;605(7909):298.
- Glinton KE, Ma WS, Lantz C, Grigoryeva LS, DeBerge M, Liu XL, Febbraio M, Kahn M, Oliver G, Thorp EB. Macrophage-produced VEGFC is induced by efferocytosis to ameliorate cardiac injury and inflammation. Journal of Clinical Investigation. 2022;132(9):15.
- Guo H, Bai W, Ouyang W, Liu Y, Wu C, Xu Y, Weng Y, Zang H, Liu Y, Jacobson L, Hu Z, Wang Y, Arafa HM, Yang Q, Lu D, Li S, Zhang L, Xiao X, Vázquez-Guardado A, Ciatti J, Dempsey E, Ghoreishi-Haack N, Waters EA, Haney CR, Westman AM, MacEwan MR, Pet MA, Rogers JA. Wireless implantable optical probe for continuous monitoring of oxygen saturation in flaps and organ grafts. Nature Communications. 2022;13(1):3009.
- Guy C, Mitrea DM, Chou PC, Temirov J, Vignali KM, Liu XY, Zhang H, Kriwacki R, Bruchez MP, Watkins SC, Workman CJ, Vignali DAA. LAG3 associates with TCR-CD3 complexes and suppresses signaling by driving co-receptor-Lck dissociation. Nature Immunology. May 2022;23(5):757.
- Heidenreich PA, Bozkurt B, Aguilar D, Allen LA, Byun JJ, Colvin MM, Deswal A, Drazner MH, Dunlay SM, Evers LR, Fang JMC, Fedson SE, Fonarow GC, Hayek SS, Hernandez AF, Khazanie P, Kittleson MM, Lee CS, Link MS, Milano CA, Nnacheta LC, Sandhu AT, Stevenson LW, Vardeny O, Vest AR, Yancy CW. 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2022;145(18):E895-E1032.
- Hunt AC, Case JB, Park YJ, Cao L, Wu K, Walls AC, Liu Z, Bowen JE, Yeh HW, Saini S, Helms L, Zhao YT, Hsiang TY, Starr TN, Goreshnik I, Kozodoy L, Carter L, Ravichandran R, Green LB, Matochko WL, Thomson CA, Vögeli B, Krüger A, VanBlargan LA, Chen RE, Ying B, Bailey AL, Kafai NM, Boyken SE, Ljubetič A, Edman N, Ueda G, Chow CM, Johnson M, Addetia A, Navarro MJ, Panpradist N, Gale M, Jr., Freedman BS, Bloom JD, Ruohola-Baker H, Whelan SPJ, Stewart L, Diamond MS, Veesler D, Jewett MC, Baker D. Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice. Science Translational Medicine. 2022;14(646):eabn1252.
- Kim ES, Velcheti V, Mekhail T, Yun C, Shagan SM, Hu S, Chaes YK, Leal TA, Dowell JE, Tsai ML, Dakhil CSR, Stella P, Jin YL, Shames DS, Schleifman E, Fabrizio DA, Phan S, Socinski MA. Blood-based tumor mutational burden as a biomarker for atezolizumab in non-small cell lung cancer: the phase 2 B-F1RST trial. Nature Medicine. 2022;28(5):939.
- Kouzu H, Tatekoshi Y, Chang HC, Shapiro JS, McGee WA, De Jesus A, Ben-Sahra I, Arany Z, Leor J, Chen CL, Blackshear PJ, Ardehali H. ZFP36L2 suppresses mTORc1 through a P53-dependent pathway to prevent peripartum cardiomyopathy in mice. Journal of Clinical Investigation. 2022;132(10):16. e154491.
- Kumar B, Field NS, Kim DD, Dar AA, Chen Y, Suresh A, Pastore CF, Hung LY, Porter N, Sawada K, Shah P, Elbulok O, Moser EK, Herbert DR, Oliver PM. The ubiquitin ligase Cul5 regulates CD4(+) T cell fate choice and allergic inflammation. Nature Communications. 2022;13(1):2786.
- Kumar D, Ison MG, Mira JP, Welte T, Hwan Ha J, Hui DS, Zhong N, Saito T, Katugampola L, Collinson N, Williams S, Wildum S, Ackrill A, Clinch B, Lee N. Combining baloxavir marboxil with standard-of-care neuraminidase inhibitor in patients hospitalised with severe influenza (FLAGSTONE): a randomised, parallel-group, double-blind, placebo-controlled, superiority trial. Lancet Infectious Diseases. 2022;22(5):718-730.
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