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Dr. Maizels is Professor of Urology at Northwestern University’s Feinberg School of Medicine and has been an attending pediatric urologist at Children's Memorial Hospital since 1980. He has been helping obstetricians and perinatologists manage fetal urological problems since 1985.

Throughout his career, he has combined his research and clinical talents to advance the treatment of urological birth defects. His research using the chick embryo has revealed mechanisms responsible for the development of renal dysplasia.  Dr. Maizels has co-authored original clinical papers on obstetric methods to forecast the outcome of fetuses with fetal hydronephrosis and worked to clarify the meaning of fetal hydronephrosis. More recently, a prospective protocol has shown the benefits of surgery for ureteropelvic junction obstruction vs. the risks of observation alone.

In 1989, Dr. Maizels served as the founding president of the Society for Fetal Urology. This nationally based group has established common methods to grade hydronephrosis by ultrasound and diagnose renal obstruction by well tempered renography.  

 Education

Undergraduate: University of California, Los Angeles, CA
Medical School: University of California School of Medicine, Los Angeles, CA
Internship: General Surgery, University Hospital at Boston University, Boston, MA
Surgery residency: University Hospital at Boston University, Boston, MA
Urology residency: McGaw Medical Center of Northwestern University, Chicago, IL
Fellowship: Pediatric Urology, Children's Memorial Hospital, Chicago, IL

Journal Articles

1. Zaontz MR, Ritchie EL, Maizels M, Firlit CF. Insertion of testicular prosthesis: use of vaginal speculum. Urology. 35(2):130-2. 1990.
2. Maizels M, Reisman ME, Flom LS, Nelson J, Fernbach S, Firlit CF, Conway JJ. Grading nephroureteral dilatation detected in the first year of life: correlation with obstruction. J Urol. 148(2 Pt 2):609-14; discussion 615-6. 1992.
3. Starr NT, Maizels M, Chou P, Brannigan R, Shapiro E. Microanatomy and morphometry of the hydronephrotic "obstructed" penal pelvis in asymptomatic infants. J Urol. 148(2 Pt 2):519-24. 1992.
4. Conway JJ, Maizels M. The "well tempered" diuretic renogram: a standard method to examine the asymptomatic neonate with hydronephrosis or hydroureteronephrosis. A report from combined meetings of The Society for Fetal Urology and members of The Pediatric Nuclear Medicine Council--The Society of Nuclear Medicine. J Nucl Med. 33(11):2047-51. 1992.
5. Cheng EY, Maizels M, Chou P, Hartanto V, Shapiro, E. Response of the newborn uteteropelvic junction complex to induced and later reversed partial ureteral obstruction in the rabbit model. J Urol. 150(2 Pt 2):782-9. 1993.
6. MacNeily AE, Maizels M, Kaplan WE, Firlit CF, Conway JJ. Does early pyeloplasty really avert loss of renal function? A retrospective review. J Urol. 150:(2 Pt 2)769-73. 1993.
7. Fernbach SK, Maizels M, Conway JJ. Ultrasound grading of hydronephrosis: introduction to the system used by the Society for Fetal Urology. Pediatr Radiol. 23(6):478-80. 1993.
8. Ritchie EL, Reisman EM, Zaontz MR, Hatch DA, Wacksman J, Maizels M. Use of kidney internal splint/stent (KISS) catheter in urinary diversion after pyeloplasty.  Urology 42:(1)55-8. 1993
9. Maizels M, Mitchell B, Kass E, Fernbach SK, Conway JJ. Outcome of nonspecific hydronephrosis in the infant: a report from the Registry of the Society for Fetal Urology. J Urol. 152(6 Pt 2):2324-7. 1994.
10. Wickstrom E, Maizels M, Sabbagha RE, Tamura RK, Cohen LC, Pergament E. Isolated fetal pyelectasis: assessment of risk for postnatal uropathy and Down syndrome. Ultrasound Obstet Gynecol. 8(4):236-40. 1996.
11. Cheng EY, Grammatopoulos T, Lee C, Sensibar J, Decker R, Kaplan WE, Maizels M, Firlit CF. Angiotensin II and basic fibroblast growth factors induce neonatal bladder stromal cell mitogenesis. J Urol. 156(2 Pt 2):593-7. 1996.
12. Seremetis GM, Maizels M. TGF-beta mRNA expression in the renal pelvis after experimental and clinical ureteropelvic junction obstruction. J Urol. 156(1):261-266. 1996.
13. Cheng EY, Maizels M. Complete duplication of the bladder and urethra in the coronal plane: case report. J Urol. 155(4):1414-5. 1996.
14. Cheng EY, Lee C, Decker RS, Sensibar JA, Lang S, Kaplan WE, Maizels M, Firlit CF. Captopril (an inhibitor of angiotensin convering enzyme) inhibits obstructive changes in the neonatal rabbit bladder. Urology. 50(3):465-71. 1997.
15. Palmer LS, Maizels M, Kaplan WE, Stokes S, Firlit CF. The influence of surgical approach and intraoperative venography on successful varicocelectomy in adolescents. J Urol. 158(3 Pt 2): 1201-4. 1997.
16. Palmer LS, Maizels M, Kaplan WE, Firlit CF, Cheng EY. Urine levels of transforming growth factor-beta 1 in children with ureteropelvic junction obstruction. Urology. 50(5):769-73. 1997.
17. Palmer LS, Andros GJ, Maizels M, Kaplan WE, Firlit CF. Management considerations for treating vesicoureteral reflux in children with solitary kidneys. Urology. 49(4):604-8. 1997.
18. Palmer LS, Maizels M, Cartwright PC, Fernbach SK, Conway JJ. Surgery versus observation for managing obstructive grade 3 to 4 unilateral hydronephrosis: a report from the Society for Fetal Urology. J Urol. 159(1):222-8. 1998.
19. Austin PF, Homsy YL, Gearhart JP, Porter K, Guidi C, Madsen K, Maizels M. The prenatal diagnosis of cloacal exstrophy. J Urol. 160(3 Pt 2): 1179-81. 1998.
20. Mathews R, Jeffs RD, Maizels M, Palmer LS, Docimo SG.  Single system ureteral ectopia in boys associated with bladder outlet obstruction. J Urol. 161(4):1297-300. 1999.
21. Han SW, Maizels M, Chou PM, Fernbach SK, Cheng EY, Furness PD III. Lamina muscularis propria thickness of renal pelvis predicts radiological outcome of surgical correction of ureteropelvic junction obstruction. J Urol. 165(5):1648-51. 2001.
22. Furness PD III, Maizels M, Han SW, Cohn RA, Cheng EY. Elevated bladder urine concentration of transforming growth factor-beta1 correlates with upper urinary tract obstruction in children. J Urol. 162(3 Pt 2):1033-6. 1999.
23. Rubenstein JN, Maizels M, Kim SC, Houston JT. The PIC cystogram: a novel approach to identify "occult" vesicoureteral reflux in children with febrile urinary tract infections. J Urol. 169(6):2339-43. 2003.
24. Maizels M, Alpert SA, Houston JT, Sabbagha RE, Parilla BV, MacGregor SN.: Fetal bladder sagittal length: a simple monitor to assess normal and enlarged fetal bladder size, and forecast clinical outcome. J Urol. 172(5 Pt 1):1995-9. 2004.
25. Williams DH, Gauthier DW, Maizels M. Prenatal diagnosis of Beckwith-Wiedemann syndrome. Prenat Diagn. 25(10):879-84. 2005.
    

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Department of Urology
Northwestern University, Feinberg School of Medicine
303 East Chicago Avenue, Tarry 16-703
Chicago, IL 60611-3008
(312) 908-8145/ Fax (312) 908-7275 E-mail: m-grant@northwestern.edu