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C. Shad Thaxton, MD, PhD
Assistant Professor
Dr. Colby Shad Thaxton graduated from the University of Colorado with a BA in Environmental Biology. He earned his MD and PhD from Northwestern University in 2004 and 2007, respectively. Joining Northwestern as full-time faculty in 2008, Dr. Thaxton's research efforts focus on translational nanotechnology. Nanotechnology is the study of the fabrication, directed self-assembly, and characterization of materials that have size dimensions between 1 and 100 nanometers. In the context of biological nanostructures, this is the size regime of the molecular machinery that constitutes, for example, functional viruses, bacteria, and human cells. The challenge of bio-nanotechnology, and the focus of The Thaxton Laboratory, is to control the synthesis of structures that naturally interface with biological systems to develop exquisitely targeted, practical, safe, and effective nanoparticle therapeutics, imaging agents, and biosensors.
For more information on Dr. Thaxton and his laboratory's research, please visit www.thaxtonlab.northwestern.edu
Undergraduate: Environmental Biology, University of Colorado, Boulder, CO
Medical School: Feinberg School of Medicine, Northwestern University, Chicago, IL
Post-graduate: Inter-Departmental Biological Sciences (Chemistry), Feinberg School of Medicine, Northwestern University, Chicago, IL
Selected Publications
The following publications are selected from a complete CV. For more information on Dr. Thaxton's scholarly productivity, please contact his office.
Journal Articles
1. Nam J.-M.1, Thaxton, C.S.1, Mirkin, C. A. Nanoparticle-Based Biobarcodes For The Ultrasenstive Detection of Proteins. Science 301:1884-1886 (2003). (1 co-first author)
2. Thaxton, C.S., Hill, H.D., Georganopoulou, D., Stoeva, S., Mirkin, C.A. A Bio-Barcode Assay Based upon Dithiothreitol Induced Oligonucleotide Release. Anal. Chem. 77(24): 8174-8178 (2005).
3. Georganopoulou, D., Nam, J.-M., Thaxton, C.S., Chang, L., Klein, W., Mirkin C.A. Nanoparticle-Based Detection in Cerebral Spinal Fluid of a Soluble Pathogenic Biomarker for Alzheimer's Disease. Proc. Natl. Acad. Sci. 102(7): 2273-2276 (2005).
4. Rosi, N., Giljohann, D., Thaxton, C.S., Lytton-Jean, A., Han, M.-S., Mirkin, C.A. Oligonucleotide-Modifed Gold Nanoparticles for Intracellular Gene Regulation. Science. 312 (5776): 1027-1030 (2006).
Northwestern University, Feinberg School of Medicine
Department of Urology
303 East Chicago Avenue, Tarry 16-703
Chicago, IL 60611
(312) 503-1826
Fax (312) 503-1867
cthaxton003@md.northwestern.edu