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Charles N. Rudick, PhD
Research Assistant Professor
Dr. Charles N. Rudick was appointed Research Assistant Professor in the Department of Urology at Northwestern University Feinberg School of Medicine in 2009. Upon graduating from the University of Michigan with a BS in Biological Psychology, he went on to earn his PhD at Northwestern University through Northwestern University Institute for Neuroscience. Dr. Rudick’s research focuses on characterizing the peripheral and central (spinal cord and brain) neuronal mechanisms of acute and chronic pain in interstitial cystitis, chronic prostatitis/chronic pelvic pain syndrome and urinary tract infection. Dr. Rudick is currently investigating the transition from acute pain to chronic pain and developing novel therapies to treat both acute and chronic pain associated with the urinary tract.
Education
Undergraduate: BS, Biological Psychology, University of Michigan, Ann Arbor, MI
Graduate: PhD, Northwestern University Institute for Neuroscience, Northwestern University Evanston, IL
Post-graduate: NIH NRSA Fellowship in Urology, the Department of Physiology and the Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL
Selected Publications
The following publications are selected from a complete CV. For more information on Dr. Rudick's scholarly productivity, please contact his office.
Journal Articles
Review Articles
1. Klumpp DJ, Rudick CN (2008). Summation model of pelvic pain in interstitial cystitis. Nature Clinical Practice. 5: 494-500.
2. Marinelli M, Rudick CN, Hu X, White FJ (2006) Excitability of dopamine neurons: modulation and physiological consequences. Special issue in Dopaminergic Neurotransmission, Current Drug Targets – CNS and Neurological Disorders 5: 79-97.
Original Research
1. Rudick CN, Bryce PJ, Guichelaar LA, Berry RE, Klumpp DJ (2008). Mast cell-derived histamine mediates cystitis pain. PLoS-One. 3:e2096. PMCD: PMC2346452
2. Rudick CN, Schaeffer AJ, Thumbikat P (2008) Experimental autoimmune prostatitis induces chronic pelvic pain. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology 294:R1268-75.
3. Rudick CN, Chen MC, Mongiu AK, Klumpp DJ (2007). Organ cross talk modulates pelvic pain. American Journal of Physiology: R egulatory, Integrative and Comparative Physiology 293: R1191-8.
4. Millecamps M, Centeno MV, Berra HH, Rudick CN, Lavarello S, Tkatch T, Apkarian AV (2007) D-cycloserine reduces neurophathic pain behavior through limbic NMDA-mediated circuitry Pain 132: 108-23.
5. Rudick CN, Gibbs RB, Woolley CS (2003) A role for the basal forebrain cholinergic system in estrogen- induced disinhibition of hippocampal pyramidal cells. Journal of Neuroscience 23(11): 4479-90.
6. Rudick CN, Woolley CS (2003) Selective estrogen receptor modulators regulate phasic activation of hippocampal CA1 pyramidal cells by estrogen. Endocrinology 144(1): 179-87.
7. Rudick CN, Woolley CS (2001) Estrogen regulates functional inhibition of hippocampal CA1 pyramidal cells in the adult female rat. Journal of Neuroscience 21(17): 6532-43.
8. Becker JB, Rudick CN, Jenkins WJ (2001) The role of dopamine in the nucleus accumbens and striatum during sexual behavior in the female rat. Journal of Neuroscience 21(9): 3236-41.
9. Gupta RR, Sen S, Diepenhorst LL, Rudick CN, Maren S (2001) Estrogen modulates sexually dimorphic contextual fear conditioning and hippocampal long-term potentiation (LTP) in rats. Brain Research 888(2): 356-365.
10. Rudick CN, Woolley CS (2000) Estradiol induces a phasic Fos response in the hippocampal CA1 and CA3 regions of adult female rats. Hippocampus 10(3): 274-83.
11. Becker JB, Rudick CN (1999) Rapid effects of estrogen or progesterone on the amphetamine-induced increase in striatal dopamine are enhanced by estrogen priming: a microdialysis study. Pharmacology Biochemistry Behavior 64(1): 53-7.
Northwestern University, Feinberg School of Medicine
Department of Urology
303 East Chicago Avenue, Tarry 16-721
Chicago, IL 60611-3008
(312) 503-0106
Fax (312) 908-7275
c-rudick@northwestern.edu