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All Clinical Trials

Northwestern Scleroderma Program Registry

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NU 05H6: Acute Leukemias and Map Kinase

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NCI 02X3: SPORE in Pancreatic Cancer Tissue Core

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HLA-Identical Sibling Renal Transplant Tolerance With Donor Hematopoietic Stem Cells and Campath-1H

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Chicago Lupus Database

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Characteristics of the Stretch Reflex Response in Various Joints

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DERMATOLOGY TISSUE ACQUISITION AND REPOSITORY

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NUGene: Gene-Disease Associations and Treatment Outcomes

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Genetics of BRCA2-related Prostate Cancer

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Mediators of Atherosclerosis in South Asians Living in America

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NU 00X3: Pathology Core Facility

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RTOG 0724 - A Phase III Randomized Study of Concurrent Chemotherapy and Pelvic Radiation Therapy with or without Adjuvant Chemotherapy in High-Risk Patients with Early-Stage Cervical Carcinoma Following Radical Hysterecotmy

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Asymmetric Neurodegeneration and Language in Primary Progressive Aphasia

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Chemokine mechanisms in chronic pelvic pain

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NU 99G8: Northwestern Ovarian Cancer Early Detection and Prevention Program: A Specimen and Data Study

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Alzheimer's Disease Research Center

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Neural Mechanisms in Sensory Reception and Processing in the Healthy Adult (VA RR&D Grant # B3302K)

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NCI 01X1: Breast Cancer Program: Tissue and Specimen Collection Facility

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MWCCS

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Peripheral Neuropathy Research Registry (PNRR)

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NU 04H7: Molecular Mechanisms of Disease Progression in Myeloid Malignancy

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A Family Study of Pragmatic Language

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Microbiomes of Pelvic Pain

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Northwestern University The Department of Psychiatry and Behavioral Sciences, Clinical Research Program (NU CRP) Recruitment Pipeline

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A PHASE 3 SINGLE CENTER STUDY OF ISLET TRANSPLANTATION IN NON-UREMIC DIABETIC PATIENTS

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A Randomized Trial to Prevent Congenital Cytomegalovirus Infection (CMV)

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A Registry of Interstitial Lung Disease Patients

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NCI 12H13: Molecular Mechanisms of Relapse After Therapy Discontinuation in Chronic Myeloid Leukemia

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CENTER FOR BEHAVIORAL INTERVENTION TECHNOLOGIES (CBITs) RESEARCH SUBJECT RECRUITMENT REGISTRY

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Targeting Siglecs in Disease

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NUDB 13C03: Northwestern Brain Tumor Institute Research Database

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Movement Disorders Biorepository

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RANDOMIZED CONVERSION OF EBV+ KIDNEY TRANSPLANT RECIPIENTS OF LIVING OR STANDARD CRITERIA DONORS AT THREE MONTHS POST TRANSPLANTATION TO BELATACEPT WITH MPA OR BELATACEPT WITH LOW-DOSE TACROLIMUS (50% OF DOSE) COMPARED TO PATIENTS REMAINING ON CENTER SPECIFIC STANDARD THERAPY OF TACROLIMUS AND MPA

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A Long-Term Non-Interventional Registry to Assess Safety and Effectiveness of HUMIRA® (Adalimumab) in Patients with Moderately to Severely Active Ulcerative Colitis (LEGACY)

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Healthy Control Esophageal Registry and Biorepository

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Neural Systems for the Dynamic Use of Memory

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Noninvasive Manipulation of Hippocampal-Cortical Brain Networks and Memory

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Development of a Kidney Cancer Patient Outcomes Database

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Synovial Macrophage Transcriptional Signatures for Predicting Therapeutic Efficacy

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HOme-based moNitORed exercise for PAD

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Ex vivo interactions between high-density-like nanoparticles and human blood

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NCI 15H01: Triad1 Regulates Myelopoiesis and Functions as a Leukemia Suppressor

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Low InTensity Exercise intervention in PAD: The LITE Trial.

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The effect of magnesium on maternal mood, cognitive function, and birth experience

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A Randomized Trial of Pessary and Progesterone for Preterm Prevention in Twin Gestation with a Short Cervix (PROSPECT)

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Telmisartan Plus Exercise to Improve Functioning in PAD

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Chronic Kidney Disease Research Biorepository

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Improving Outpatient Safety of Older Adults through Electronic Patient Portals

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High Resolution and Functional MRI Assessment of Intracranial Atherosclerotic Plaque

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LIFT: Lupus Intervention for Fatigue Trial

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The ENabling Reduction of low-Grade Inflammation in SEniors) Pilot Study

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A large-scale multicenter phase II study evaluating the protective effect of a tissue selective estrogen complex (TSEC) in women with newly diagnosed ductal carcinoma in situ.

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NU 15N01: Head and Neck Tissue Bank

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NU 15N02: Northwestern Head and Neck Cancer Registry

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Motivational Interviewing and Physical Activity in Parkinson’s Disease

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Semen quality in males with inflammatory bowel disease: Influence of medication for IBD

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Epidermolysis Bullosa Clinical Characterization and Outcomes Database

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North American Registry for Care and Research in Multiple Sclerosis (NARCRMS) Study

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LiveWell: A Mobile Intervention for Bipolar Disorder

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Efficacy of Couples-Based HIV Prevention in Vulnerable Young Men

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Cocoa to Improve Walking Performance in Peripheral Artery Disease: The COCOA-PAD Study

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MAST CELLS IN MALE CHRONIC PELVIC PAIN AND LOWER URINARY TRACT DYSFUNCTION

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Evaluating the Circadian Response to Light in Delayed Sleep-Wake Phase Disorder

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A wearable myoelectric-computer interface to reduce muscle co-activation in acute and chronic stroke

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Alzheimer’s Disease Neuroimaging Initiative 3

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NUDB 16Z01: The OncoSET Program Database and Biobank - Combining Clinical Outcomes with Next Generation Sequencing and other Advanced Molecular Testing for Genetic Aberrations in Patients with Advanced Solid Malignancies

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MISCEND

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Improve PAD PERformance with METformin: The PERMET Trial

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Reducing Assessment Barriers for Patients with Low Literacy

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Investigating Serum Concentrations of Mood Stabilizing Medications in Pregnancy and Postpartum

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Enroll-HD: A Prospective Registry Study in a Global Huntington’s Disease Cohort

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ELUCDITATING THE MOLECULAR MECHANISMS UNDERLYING CYP2D6 INDUCTION DURING PREGNANCY

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Gore TAG-TBE

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Neuromodulation and Neurorehabilitation for Treatment of Functional Deficits after mTBI plus PTSD

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INtervention Study In OverweiGHT Patients with COPD (INSIGHT COPD)

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The Role of Circadian Dysfunction in Hepatic Encephalopathy in Patients with Cirrhosis

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Bimanual balanced reaching with visual biofeedback

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Clinical Research Consortium for the Study of Cerebellar Ataxia (CRC-SCA) to Study Natural History and Genetic Modifiers in Spinocerebellar Ataxia (SCA)

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Partner 3 AVIV Registry

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Long-Term Nicotine Treatment of Mild Cognitive Impairment

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A Randomized Trial of Pessary in Singleton Pregnancies with a Short Cervix (TOPS)

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Physical activity and DNA methylation among women with high breast density

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Melanoma and Skin Cancer Tissue Repository

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Combined Phase 3, Double-blind, Randomized, Placebo-Controlled Studies Evaluating the Efficacy and Safety of Filgotinib in the Induction and Maintenance of Remission in Subjects with Moderately to Severely Active Crohn’s Disease

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Quantitative Detection of Coronary Microvascular Dysfunction in Long COVID Patients Using a Comprehensive, Rapid, Free-Breathing Cardiovascular MRI

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A Randomized, Double-Blind, Placebo-Controlled, 52-Week Phase II Study to Evaluate the Efficacy of Intravenous RO7046015/Prasinezumab (PRX002) in Participants with Early Parkinson’s Disease with a 6-Year All-Participants-On-Treatment Extension (PASADENA)

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D-Cycloserine for the Treatment of Chronic, Refractory Low Back Pain

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Transformative Research In Diabetic Nephropathy (TRIDENT) (SP0043185)

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The Role of Positron Emission Tomography and Magnetic Resonance Imaging (without Fluorodeoxyglucose or Gadolinium) in Yttrium-90 Radioembolization Treatment Planning for Patients with Liver Malignancies

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Brain Stimulation and Memory Study

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Genetic causes and pathogenic mechanisms of adult epilepsies

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Alterations of Sleep and Circadian Timing in Aging

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NIH All of Us Research Program Precision Medicine Initiative® Precision Medicine Initiative Cohort Program Healthcare Provider Organization Enrollment Centers

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Clinical Database of Prostate Cancer at Northwestern University

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Bilateral Priming plus Task Specific Training for Severe Upper Limb Hemiparesis

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Strengthening Circadian Signals to Enhance Cardiometabolic Functions

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APOLLO

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cIRB: AtRial Cardiopathy and Antithrombotic Drugs In prevention After Crypotgenic Stroke

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A Natural History Observation and Registry Study of Macular Telangiectasia Type 2: The MACTEL Study

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A Phase III Multicenter Randomized, Sham Controlled, Study to Determine the Safety and Efficacy of Renexus® in Macular Telangiectasia type 2

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(xIRB) The CHRONICLE Study: A Longitudinal Prospective Observational Study of the Characteristics, Treatment Patterns and Health Outcomes of Individuals with Severe Asthma in the United States

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Clinical Trial Readiness for SCA1 and SCA3

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CHRONIC VENOUS THROMBOSIS: RELIEF WITH ADJUNCTIVE CATHETER-DIRECTED THERAPY

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Mitochondrial Dysfunction and Disability in Peripheral Artery Disease

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Vasculitis Clinical Research Consortium (VCRC) Genetic Repository One Time DNA Protocol

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Evaluation of Renal Microvascular Perfusion by Contrast Enhanced Ultrasound

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A Phase 3, Randomized, Rater-Blinded, Multi-Center Study to Evaluate the Efficacy and Safety of ALXN1840 Administered for 48 Weeks Versus Standard of Care in Patients with Wilson Disease Aged 12 Years and Older with an Extension Period of Up to 60 Months

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Longitudinal Early-onset Alzheimer’s Disease Study (LEADS)

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Effects of device-assisted practice of activities of daily living in a close-to-normal pattern on upper extremity motor recovery in individuals with moderate to severe stroke

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Randomized Controlled Trial of a Mindfulness-based Intervention in a Federally Qualified Center (FQHC)

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Pathogenic Wnt-beta catenin target genes in macrophages and fibrosis

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A Randomized, Multicenter, Double-Blind, Parallel, Active-Control Study of the Effects of Sparsentan, A Dual Endothelin Receptor and Angiotensin Receptor Blocker, on Renal Outcomes in Patients with Primary Focal Segmental Glomerulosclerosis

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A pragmatic trial of two strategies for implementing an effective eHealth HIV prevention program (Keep It Up! 3.0)

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Gut Microbial remodeling with Resistant Maltodextrin for motor and non-motor symptoms in Parkinson's disease: safety and tolerability study.

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Project 1, Adaptations of the brain in chronic pain with opioid exposure

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Wearable sensors and video recording for children (birth to 24 months) to monitor motor development

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The Collaborative, National Quality and Efficacy Registry (CONQUER)

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Testing Intervention Strategies for Addressing Obesity and Binge Eating

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Brain pathophysiology of osteoarthritis pain

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AF STOP: AF Substrate as an Outcome and Predictor of successful AF ablation

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Real-time Wideband Cardiac MRI for Patients with a Cardiac Implantable Electronic Device

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PK and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

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The effect of inflammatory bowel disease flares on serum prostate specific antigen

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Wool Clothing for Atopic Dermatitis

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(xIRB NCI CIRB) CCTG MA.39: TAILOR RT: A Randomized Trial Of Regional Radiotherapy In Biomarker Low Risk Node Positive Breast Cancer

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CalorieHarmony for Obesity

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Randomized trial of Retropubic versus Single-incision Mid-Urethral Sling (Altis™) for Concomitant Management of Stress urinary incontinence during Native Tissue Vaginal Repair

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Impaired sensorimotor integration for prosodic speech production in Ataxic Dysarthria

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BP40283 -Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Assess The Effects of RO6889450 in Patients with Schizophrenia or Schizoaffective Disorder and Negative Symptoms

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CLASP IID/IIF

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NU 18B05: A Phase II Study of the Determinants of Transdermal Drug Delivery to the Normal and the Radiated Breast

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The Impact of Low Flow Nocturnal Oxygen Therapy on Hospital Admissions and Mortality in Patients with Heart Failure and Central Sleep Apnea.

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Characterization of the microbiome in cutaneous T cell lymphoma

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Advancing Liver Therapeutic Approaches (ALTA). The ALTA Consortium Study Group for the management of portal hypertension – A 5-year longitudinal observation study of patients with cirrhosis undergoing TIPS placement

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(xIRB NCI) SWOG 1706: A Phase II Randomized Trial of Olaparib (NSC-747856) Administered Concurrently with Radiotherapy versus Radiotherapy Alone for Inflammatory Breast Cancer

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A Phase 3, Multicenter, Randomized, Placebo- and Active Comparator-Controlled Study Evaluating the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Subjects ((≥6 To <18 Years of Age)

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A Longitudinal Observational Study of Patients Undergoing Therapy for Immune-Mediated Inflammatory Skin Conditions

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(xIRB) NRG-BN005 A Phase II Randomized Trial of Proton vs. Photon Therapy (IMRT) for Cognitive Preservation in Patients with IDH Mutant, Low to Intermediate Grade Gliomas.

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A Master Protocol To Evaluate Biomarker-Driven Therapies And Immunotherapies In Previously-Treated Non-Small Cell Lung Cancer (Lung-MAP Screening Study)

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Modulating stimuli intensity to improve clinical outcomes in aphasia treatment

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A Prospective, Multicenter Study of Artemis a Minimally Invasive Neuro Evacuation Device, in the Removal of Intracerebral Hemorrhage (MIND)

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NU MTBC 18M02: International Melanoma Tissue Bank Consortium Site at Northwestern University

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A Phase 3, Multinational, Double-Blind, Randomized, Placebo-Controlled Study of MGL-3196 (resmetirom) in Patients With Non-Alcoholic Steatohepatitis (NASH) and Fibrosis to Resolve NASH and Reduce Progression to Cirrhosis and/or Hepatic Decompensation

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A041702: A Randomized Phase III Study of Ibrutinib Plus Obinutuzumab Versus Ibrutinib Plus Venetoclax and Obinutuzumab in Untreated Older Patients (= 70 Years of Age) with Chronic Lymphocytic Leukemia (CLL)

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Yttrium-90 Radiation Lobectomy: Dose Optimization and Prediction of FLR Hypertrophy to Enable Resection of Hepatic Malignancies

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Phase III Randomized Trial of Concurrent Chemoradiotherapy with or without Atezolizumab in Localized Muscle Invasive Bladder Cancer

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Natural history study of ALS and other motor neuron disorders

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A PHASE 3 TRIAL OF THE EFFICACY AND SAFETY OF BARDOXOLONE METHYL IN PATIENTS WITH AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE – Protocol 402-C-1808

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Parkinson’s Foundation Genetic Research Initiative

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(XIRB) DRUG IMSA101-101: Phase I/IIA Safety and Efficacy Study of IMSA101 in Patients with Advanced Treatment-Refractory Malignancies

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GSO 18-01 (REDUCE PAS)

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BTCRC HN17-111: Phase II trial of androgen deprivation therapy (ADT) and pembrolizumab for advanced stage androgen receptor-positive salivary gland carcinoma

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PD-inhibitor (Nivolumab) and Ipilimumab followed by nivolumab vs. VEGF TKI cabozantinib with nivolumab in metastatic untreated REnal Cell CancEr [PDIGREE]

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A PHASE III, MULTICENTER, RANDOMIZED, VISUAL ASSESSORMASKED, ACTIVE COMPARATOR STUDY OF THE EFFICACY, SAFETY, AND PHARMACOKINETICS OF THE PORT DELIVERY SYSTEM WITH RANIBIZUMAB IN PATIENTS WITH DIABETIC MACULAR EDEMA (PAGODA)

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Parkinson's Disease: Intervening Early Concerning Employment (PIECE) Aims 2 and 3

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(xIRB) NCI CIRB NRG GY019: A Randomized Phase III, Two-Arm Trial of Paclitaxel/Carboplatin/Maintenance Letrozole Versus Letrozole Monotherapy in Patients with Stage II-IV, Primary Low-Grade Serous Carcinoma of the Ovary or Peritoneum

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Project 1, Adaptations of the Brain in Chronic Pain with Opioid Exposure

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(xIRB) NCI CIRB: Alliance A071701: Genomically-Guided Treatment Trial in Brain Metastases

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MultiStem® Administration for Stroke Treatment and Enhanced Recovery Study (MASTERS-2) (Protocol #: B01-04)

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A Phase 1 Single- and Multiple-Ascending-Dose Study to Assess the Safety, Tolerability, and Pharmacokinetics of BIIB094 Administered Intrathecally to Adults With Parkinson’s Disease (Protocol# 254PD101)

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Pathogenesis of Heart Failure with Preserved Ejection Fraction in Chronic Kidney Disease

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(xIRB) Social Processing in Remitted Adolescent Depression

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(xIRB) NCI CIRB ECOG-ACRIN 2182: A Randomized Phase II Study of De-Intensified ChemoRadiation for EarlyStage Anal Squamous Cell Carcinoma (DECREASE)

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RV Ischemia & Fibrosis in CTEPH

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NU 19H08: Signal Transduction of Type I Interferons in Malignant Cells

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Randomized controlled trial assessing transperineal prostate biopsy to reduce infection complications

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xIRB ALLFTD: ARTFL-LEFFTDS LONGITUDINAL FRONTOTEMPORAL LOBAR DEGENERATION

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Study in Parkinson Disease of Exercise Phase 3 Clinical Trial: SPARX3

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XIRB A master protocol for randomized, placebo-controlled, Phase 2 clinical trials of multiple interventions for the treatment of chronic pain

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(xIRB) DRUG JCAR017-FOL-001: A Phase 2, Open-Label, Single-Arm, Multicohort, Multicenter Trial to Evaluate the Efficacy and Safety of jcar017 in Adult Subjects with Relapsed or Refractory Indolent B-Cell Non-Hodgkin Lymphoma (NHL) (Transcend FL)

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TAMBE Pivotal AAA 17-01

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REPAIR-MR

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Comparison of disease knowledge in dyads of parents and their adolescents with chronic skin disorders

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TeleHD: Feasibility, validity, and value of telemedicine for motor and non-motor assessments in patients with Huntington’s Disease (HD)

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A Multicenter, Adaptive, Randomized Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for the Treatment of COVID-19 in Hospitalized Adults

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A PHASE II STUDY TO EVALUATE THE SAFETY AND EFFICACY OF OQL011 ON VEGFR INHIBITOR-ASSOCIATED HAND-FOOT SKIN REACTION IN CANCER PATIENTS

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Oxidative Markers and Efficacy in ALS/MND Phenotypes Treated with Edaravone (Loma Linda)

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Angiotensin II for Distributive Shock

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CPIRA-2

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Sensory-specific peripheral stimulation for tremor management

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Cure Glomerulonephropathy

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A Phase 1/2a Open-Label Ascending Dose Study to Evaluate the Safety and Effects of LY3884961 in Patients with Parkinson’s Disease with at Least One GBA1 Mutation (PROPEL, Protocol #: J3Z-MC-OJAA previously called PRV-PD101)

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The role of the cortex and brainstem in motor preparation for proximal and distal upper extremity movements

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NU COVID-19 MSK20H04: Examining COVID19 Course and Outcomes in Patients Previously Diagnosed with Chronic Lymphocytic Leukemia (CLL)

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NU FC19L02: Phase II randomized trial of carboplatin + pemetrexed + bevacizumab, with or without atezolizumab in stage IV non-squamous NSCLC patients who harbor a sensitizing EGFR mutation or have never smoked

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Platform Trial for the Treatment of Amyotrophic Lateral Sclerosis (ALS): A perpetual multi-center, multi-regimen clinical trial evaluating the safety and efficacy of investigational products for the treatment of ALS.

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Cardio-TTRansform (ION-682884-CS2)

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NP-SLE

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The Parkinson’s Progression Markers Initiative (PPMI) 2.0 Clinical - Establishing a Deeply Phenotyped PD Cohort

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Screening for Coronavirus Antibodies in Neighborhoods (SCAN)

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Immune checkpoint inhibitor-associated acute kidney injury

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Amplify Gait to Improve Locomotor Engagement in Spinal Cord Injury (AGILE SCI) Trial

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ALL-IN

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AHEAD 3-45 Study

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Prospective evaluation of an applied ATTR-CM Machine Learning model to a health system electronic health record (EHR)

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(xIRB) DRUG AVM-003-HC: Phase 3 Multicenter, Double-Blind, Placebo-Controlled Trial of Viralym-M (ALVR-105) for the Treatment of Patients With Virus-Associated Hemorrhagic Cystitis After Allogeneic Hematopoietic Cell Transplant.

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(xIRB) NCI CIRB ECOG-ACRIN 2185: Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs

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A Sequenced Strategy for Improving Outcomes in People with Knee Osteoarthritis Pain (SKOAP)

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African-American Social Support Effectiveness Treatment-Partners alleviating Perinatal Depression (ASSET-PPD)

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A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of AL001 in Individuals at Risk for or With Frontotemporal Dementia Due to Heterozygous Mutations in the Progranulin Gene

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COVID Prevention Trials Registry

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Phase 1/2 trial of blood-brain barrier opening with the SonoCloud-9 implantable ultrasound device and treatment with albumin-bound paclitaxel in patients with recurrent glioblastoma

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Human-like Robot Controllers for Enhanced Motor Learning

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NRG HN006: Randomized Phase II/III Trial of Sentinel Lymph Node Biopsy Versus Elective Neck Dissection for Early-Stage Oral Cavity Cancer

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(xIRB) NCI CIRB ECOG-ACRIN 2186: A Randomized Phase II Study of Gemcitabine and Nab-Paclitaxel Compared with 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan in Older Patients with Treatment Naïve Metastatic Pancreatic Cancer (GIANT)

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COVID-19 TestUS an initiative of RADx AcceleRATeD study (Rapid Assessment of Technology for SARS-CoV-2 Detection)

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Prospective Molecular Profiling To Guide Therapeutic Decision-making in Patients with Advanced Hepatocellular Cancer (HCC): An Insight to Next Generation Sequencing-Matched Systemic Therapy in Liver Cancer (PROTOLIGHT STUDY)

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Impact of immunotherapy-related skin diseases on quality of life

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(xIRB NCI CIRB) ECOG-ACRIN 1181: Preoperative THP and Postoperative HP in Patients Who Achieve a Pathologic Complete Response Part 1 Component of: The CompassHER2 Trials (COMprehensive Use of Pathologic Response ASSessment to Optimize Therapy in HER2-Positive Breast Cancer) (CompassHER2-pCR)

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R1: Telehealth Pain Self-Management for Employed Adults (E-TIPS)

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DRUG CCTL019B2003I: Managed Access Program (MAP) Cohort Treatment Plan CCTL019B2003I to provide access for patients with out of specification leukapheresis product and/or out of specification manufactured tisagenlecleucel (CTL019; Kymriah®).

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Evaluating the EVO treatment optimized for resource constraints: Elements Vital to treat Obesity

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(xIRB) NCI CIRB ETCTN 10300: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 1 (BLAST MRD AML-1): A Randomized Phase 2 Study of the Anti-PD-1 Antibody Pembrolizumab in Combination with Conventional Intensive Chemotherapy as Frontline Therapy in Patients with Acute Myeloid Leukemia

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xIRB Consortium of Early Arthritis Cohorts USA (CATCH-US) -- A prospective cohort study of adults with new onset inflammatory arthritis symptoms to understand predictors of optimal outcomes

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NU MSK19H03 : Combination Therapy with Entinostat and Pembrolizumab in Relapsed and Refractory Lymphomas

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(xIRB) NCI CIRB SWOG 1823: A Prospective Observational Cohort Study to Assess mRNA 371 for Outcome Prediction in Patients with Newly Diagnosed Germ Cell Tumors

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Tape Strip Analysis in Dermatologic Diseases

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Alliance A021806: A Phase III Trial of Perioperative Versus Adjuvant Chemotherapy for Resectable Pancreatic Cancer

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(xIRB) NCI CIRB ETCTN 10217: A Phase 1b Biomarker-Driven Combination Trial of Copanlisib, Olaparib, and MEDI4736 (Durvalumab) in Patients with Advanced Solid Tumors

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ECOG-ACRIN Q172

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OPT2MOVE

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Use of Glenohumeral Injections for Management of Shoulder Pain in Individuals with ALS

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A Prospective and Retrospective Clinical, Histological and Molecular Analysis of the Spectrum of Cutaneous Presentations in Adult Patients Admitted to the Hospital

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TRISCEND II

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A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel Arm, Multicenter Study Evaluating the Efficacy and Safety of Pridopidine in Patients with Early Stage of Huntington Disease

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High vs. Standard Dose Influenza Vaccine in Adult SOT Recipients

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Serial Monitoring of Circulating Tumor Cells During Radiotherapy for Women with Non-Metastatic Breast Cancer: A Prospective Observational Cohort Study

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A multicenter, double-blind, randomized study to evaluate the effects of tasimelteon vs. placebo in participants with Delayed Sleep-Wake Phase Disorder (DSWPD)

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iCLAS™ for Persistent Atrial Fibrillation

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Glycemic Observation and Metabolic Outcomes in Mothers and Offspring

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(xirb) DRUG DEK-DKK1-P205: A Phase 2a, Multicenter, Open-Label Study of DKN-01 in Combination with Tislelizumab ± Chemotherapy as FirstLine or Second-Line Therapy in Adult Patients with Inoperable, Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma (DisTinGuish)

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Social Correlates Of Variation In Intestinal And Oral Microbiome Among Hematopoietic Stem Cell Transplant Patients: A Geographic Exploration In The City Of Chicago

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Depression MRI Research Study

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DRUG Q702-ONC-P1-US001 A Phase 1 Multicenter, Open-label, Dose-Escalation, Safety, Pharmacodynamic, Pharmacokinetic Study of Q702 with a Cohort Expansion at the RP2D in Patients with Advanced Solid Tumors

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Neural Correlates of Acute Pain Dynamics

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NAV3-32: A Comparison of Tc 99m Tilmanocept Quantitative Imaging with Immunohistochemical (IHC) Analysis of CD206 Expression in Synovial Tissue from Subjects Clinically Diagnosed with Rheumatoid Arthritis (RA)

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A prospective, multicenter, randomised, double-blind, placebo-controlled, parallel groups, phase 3 study to compare the efficacy and safety of masitinib in combination with Riluzole versus placebo in combination with Riluzole in the treatment of patients suffering from Amyotrophic Lateral Sclerosis (ALS)

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A Phase 3b, Multicenter, Randomized, Double-Blind Study to Evaluate Efficacy and Safety of Oral Edaravone Administered for a Period of 48 Weeks in Subjects with Amyotrophic Lateral Sclerosis (ALS)

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(xIRB) NCI CIRB NRG BN009: Phase III Trial of Salvage Stereotactic Radiosurgery (SRS) or SRS + Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) for First or Second Distant Brain Relapse After Upfront SRS With Brain Metastasis Velocity >/= 4 Brain Metastases/Year

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A Double-Blind Placebo-Controlled, Randomized 18-Month Phase 2A Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinectics of Oral UCB0599 in Study Participants with Early Parkinson’s Disease

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REBALANCE

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Catalyst

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DEFINE Afib

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Precision MRI of Left Atrial Fibrosis for Patients with Atrial Fibrillation

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DAPA ACT HF-TIMI 68

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Stimulating neuroplasticity in TBI with acute intermittent hypoxia

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DRUG JCAR017-EAP-001: Expanded Access Protocol (EAP) for Patients Receiving Lisocabtagene Maraleucel That Is Nonconforming for Commercial Release

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EMBARK (MYK-461-019)

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xIRB TRC-PAD Program: In-Clinic Trial-Ready Cohort

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Improving emotional well-being and quality of life in older adults experiencing dementia-related fear

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NRG GU009: Parallel Phase III Randomized Trials for High Risk Prostate Cancer Evaluating De-Intensification for Lower Genomic Risk and Intensification of Concurrent Therapy for Higher Genomic Risk with Radiation (PREDICT-RT*)

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A multi-center single arm Phase II study to evaluate the safety and efficacy of genetically engineered autologous cells expressing anti-CD20 and anti-CD19 specific chimeric antigen receptor in subjects with relapsed and/or refractory diffuse large B cell lymphoma (DLBCL)

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PLS Natural History Study (PNHS)

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(xIRB) NCI CIRB ECOG-ACRIN 8185: Phase 2 Study of Bladder-SparIng ChemoradiatioN with MEDI4736 (Durvalumab) in Clinical Stage 3, Node PosItive BladdeR CancEr (INSPIRE)