ATC Abstracts & Presentations

Juan Caicedo, MD

• Approach to the Living Liver Donor with Steatosis
• Racial and Ethnic Disparities: What We Know, Don’t Know, and What We Can Do About it

Akansha Agrawal, MD

• Evaluation of Genetic Kidney Diseases in Living Donor Candidates When Related Recipient Diagnosis is Known (e.g. ADPKD, COL4 Nephropathies, Fabry Disease)

John Franklin, MD

• A Culturally Tailored Program for African Americans

Dinee Simpson, MD

• The Road to Equity: Developing Health System Interventions to Narrow Disparities in Solid Organ Transplantation

Anat Tambur, PhD DMD

• Down to the Details: Potential Pitfalls and Limitations of HLA-Epitope Matching

Rebecca Duke, DNP, MSN, APRN-CNP

• Nursing Burnout in Transplant

James Mathew, PhD

• Non-invasive Diagnosis of Rejections in Blood and Urine by Monitoring Donor Reactive T Cell Clones

Joseph Leventhal, MD PhD FACS

• Utility of Blood Chimerism for Monitoring and Detection of Graft Versus Host Disease in SOT

Vikram Aggarwal, MD DNB

• Destination Dialysis: The ESRD Patient Ineligible for Kidney Transplant: Home-dialysis Therapies are the Next Best Option

Robert Lewandowski, MD FSIR

• Destination HCC Treatment: Ablation vs Radioembolization in the Non-transplantable HCC Patient

Long-term mortality prediction in patients with cirrhosis with laboratory data: comparisons of multiple machine-learning methods

• A. A. Huang{1}, B. J. Hasjim{1}, P. Polineni{1}, M. M. Dehchesmeh{2}, S. L. Olson{1}, L. Zhao{1}, K. Guo{1}, J. Jung{1}, J. Doll{1}, T. Banea{1}, S. Mehrotra{2}, D. P. Ladner{1}, {1}Northwestern University Feinberg School of Medicine, Chicago, IL, {2}Northwestern University, Evanston, IL

• M. Meneghini{1}, A. Armstrong Antunes{1}, D. Isaacson{2}, C. Maguire{1}, A. Tambur{1}, {1}Transplant Immunology Laboratory, Northwestern University, Chicago, IL, {2}Urology, Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL

A Successful Double Lung and Kidney Transplant Despite Strongly Positive T and B-Cell Cross Match

• S. Metwally, J. Portocarrero Caceres, J. Friedewald, A. Desai, A. Agrawal, D. Pinelli, A. Tambur, A. Arunachalam, R. Tomic, A. Bharat, S. Nadig, M. Ansari, Northwestern University, Chicago, IL

HLA Molecular Mismatches and Induced Donor-Specific Tolerance in Kidney Transplantation

• A. Senev{1}, A. Tambur{2}, V. Kosmoliaptsis{3}, H. C. Copley{3}, S. Ildstad{4}, J. R. Leventhal{5}, {1}Comprehensive Transplant Center, Northwestern University, Chicago, IL, {2}Northwestern University, Chicago, IL, {3}University of Cambridge, Cambridge, United Kingdom, {4}University of Louisville, Louisville, KY, {5}Surgery, Northwestern Medicine, Chicago, IL

Improving Informed Consent for Living Liver Donors: What Information Do Donors Want About Their Recipient?

• A. Chen{1}, A. Carroll{1}, E. Gordon{2}, J. Levitsky{1}, {1}Northwestern University Feinberg School of Medicine, Chicago, IL, {2}Department of Surgery, Vanderbilt University Medical Center, Nashville, TN

Acute Cellular Rejection in Elderly Lung Transplant Recipients During First Year Post Transplant

• H. Kleiboeker{1}, C. Kane{1}, K. Paplaczyk{2}, J. Lysne{2}, A. Prom{1}, R. Tomic{2}, A. Arunachalam{3}, {1}Pharmacy, Northwestern Memorial Hospital, Chicago, IL, {2}Northwestern Memorial Hospital, Chicago, IL, {3}Northwestern University, Chicago, IL

Association of HLA Molecular Mismatch with Risk and Severity of Rejection in Kidney Transplant Recipients

• A. Kushner{1}, C. Rebello{1}, T. Whisenant{2}, A. Tambur{1}, S. Park{1}, K. Guo{1}, L. Zhao{1}, J. Friedewald{1}, {1}Northwestern University, Chicago, IL, {2}UCSD, San Diego, CA

Endothelial Connexin 43 Gap Junctions in Ischemia-Reperfusion Injury - Role and Therapeutic Implications for Solid Organ Transplantation

• D. Jaishankar, M. Taylor, Y. Lee, A. P. Strouse, S. N. Nadig, Northwestern University, Chicago, IL

Ex Vivo Preconditioning of Human Kidney with PHD Inhibitor Upregulates HIF Target Genes with a Goal to Mitigate Ischemia-Reperfusion Injury Prior to Transplant

• B. Y. Bishop{1}, R. Tiwari{2}, M. E. Taylor{2}, D. Jaishankar{2}, S. Nadig{1}, P. Kapitsinou{1}, {1}Feinberg School of Medicine at McGaw Medical Center, Northwestern University, Chicago, IL, {2}Northwestern University, Chicago, IL

Infectious Complications in Elderly Lung Transplant Recipients During First Year Post-Transplant

• H. Kleiboeker{1}, C. Kane{2}, J. Lysne{3}, K. Paplaczyk{3}, A. Prom{1}, R. Tomic{3}, A. Arunachalam{4}, {1}Pharmacy, Northwestern Memorial Hospital, Chicago, IL, {2}Pharmacy, Northwestern Memorial Hopsital, Chicago, IL, {3}Northwestern Memorial Hospital, Chicago, IL, {4}Northwestern University, Chicago, IL

Recipient Macrophage-Derived Xbp1 Mitigates Ischemia and Reperfusion Injury Mediated via Regulating TGFβ1/KLF4 Pathways Response Following Kidney Transplantation

• X. Zheng, S. Jeyamogan, C. Chen, L. VanOsdol, S. Han, Y. Han, J. Wang, J. Mathew, Z. J. Zhang, Comprehensive Transplant Center and Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL

The Xbp1s Agonist IXA4 Regulates Bile Acids in the Abcb4-knockout Model of Primary Sclerosing Cholangitis

• A. J. Benintende{1}, M. Naibryf{1}, B. LeCuyer{1}, E. Saez{2}, L. Wiseman{2}, R. M. Green{1}, {1}Northwestern University - Feinberg School of Medicine, Chicago, IL, {2}Molecular Medicine, Scripps Research, La Jolla, CA

Infectious Complications of Lung Transplant for Covid-Associated Lung Injury (cali): A Single Center Case-Control Cohort Study

• R. Osborn{1}, M. Alamri{2}, T. Rade{1}, M. Ison{3}, {1}Northwestern Memorial Hospital, Chicago, IL, {2}McGaw Medical Center of Northwestern University, Chicago, IL, {3}Northwestern University Feinberg School of Medicine, Chicago, IL

 Deciphering HLA-DQ Immunogenicity: A Small Step Forward

• C. Maguire{1}, P. Crivello{2}, S. Heidt{3}, V. Kosmoliaptsis{4}, A. Tambur{5}, {1}Transplant Immunology, Northwestern University, Chicago, IL, {2}UK-Essen, Essen, Germany, {3}Leiden Medical Center, Leiden, Netherlands, {4}U of Cambridge, Cambridge, United Kingdom, {5}Northwestern University, Chicago, IL

A Phase 2 Multi-Center, Prospective, Randomized, Double-Blind Study to Assess Efficacy and Safety of Nitazoxanide Treatment of Norovirus in Transplant Recipients

• C. Boutin{1}, M. A. Callegari{1}, D. Florescu{2}, M. Nguyen{2}, D. Kaul{2}, R. Avery{2}, P. Chong{2}, C. Fisher{2}, A. Limaye{2}, L. Clough{2}, S. Pergam{2}, M. Green{2}, M. Michaels{2}, L. Danziger-Isakov{2}, M. Angarone{1}, L. Keefer{2}, A. Daud{1}, M. Ison{1}, {1}Northwestern University FSM, Chicago, IL, {2}NNITS Study Group, Chicago, IL

Changes in Endothelial and Proximal Tubule Cells in Focal Segmental Glomerulosclerosis: Single-Cell Resolution of Human Renal Allografts with Recurrent Disease

• L. Gallon{1}, H. Zubair{2}, A. C. Shetty{2}, J. McDaniels{2}, T. Rousselle{2}, S. Azim{2}, C. Kuscu{3}, C. Kuscu{3}, J. Eason{4}, D. Maluf{5}, V. Mas{2}, {1}Northwestern University NMFF, Chicago, IL, {2}Surgical Sciences, University of Maryland, Baltimore, MD, {3}UTHSC, Memphis, TN, {4}James D. Eason Transplant Institute, Memphis, TN, {5}Program in Transplantation, University of Maryland, Baltimore, MD

Complications of Anticoagulation in Lung Transplant Recipients on Concurrent Azole Antifungal Therapy

• A. Rubino, K. Cunningham, C. D'Agostino, K. Paplaczyk, R. Arora, H. Kleiboeker, A. Prom, C. Kane, Northwestern Memorial Hospital, Chicago, IL

Assessment of BioFire® Pneumonia Panel Utility in Lung Transplant Recipients with Concern for Respiratory Infection 

• M. Alamri{1}, J. Moore{2}, S. Sutton{2}, M. Ison{3}, {1}McGaw Medical Center of Northwestern University, Chicago, IL, {2}Northwestern Memorial Hospital, Chicago, IL, {3}Northwestern University Feinberg School of Medicine, Chicago, IL

Clinical Course of Norovirus in Adult and Pediatric Solid Organ and Hematopoietic Stem Cell Transplant Recipients:a Multi-Center, Retrospective Study

• M. A. Callegari{1}, L. Danziger-Isakov{2}, A. Rose{2}, D. Kaul{2}, K. Shaffer{2}, P. Chong{2}, D. Florescu{2}, K. German{2}, R. Avery{2}, M. Nguyen{2}, B. Wildfeuer{2}, M. Michaels{2}, M. Green{2}, L. Zhao{3}, K. Guo{3}, A. Daud{3}, M. Ison{3}, {1}Northwestern University Feinberg School of Medicine, Chicago, IL, {2}NNITS Study Team, Chicago, IL, {3}Northwestern University FSM, Chicago, IL

In Vitro Differentiation of Hematopoietic Stem Cells Into Immunoregulatory T and Myeloid Cells Following Allogeneic Stimulation

• J. M. Sanders, J. R. Leventhal, J. M. Mathew, Surgery-Comprehensive Transplant Center, Northwestern University, Chicago, IL

Tolerogenic Potential of FOXP3+ Exosomes Derived from Alloantigen Specifically Expanded Regulatory T Cells

• S. Jeyamogan, J. Sanders, M. Gunasekaran, J. He, S. Kaushal, J. Leventhal, J. Mathew, Northwestern University, Chicago, IL

Utilization of Oral Step-Down Antiviral Therapy May Decrease Length of Hospital Admission for Resistant Cytomegalovirus After Solid Organ Transplant: A Real World Case Series

• H. Kleiboeker{1}, J. Fose{2}, L. T. Schulz{2}, D. Mandelbrot{2}, J. Odorico{3}, C. Saddler{4}, J. Smith{4}, M. Jorgenson{5}, {1}Pharmacy, Northwestern Memorial Hospital, Chicago, IL, {2}UW Health, Madison, WI, {3}University of Wisconsin Hospital & Clinic, Madison, WI, {4}University of Wisconsin Infectious Disease, Madison, WI, {5}University of Wisconsin Health, Madison, WI

Multi-Institutional Validation of Automated AI Banff Lesion Score Predictions from Renal Allograft Biopsies

• L. A. Cooper{1}, A. B. Farris{2}, L. Allegretti{3}, D. A. Gutman{2}, C. Rebello{1}, J. Hogan{4}, J. Friedewald{1}, {1}Northwestern University, Chicago, IL, {2}Emory University, Atlanta, GA, {3}University of Wisconsin, Madison, WI, {4}Université de Paris, Paris, France

Community-Level Social Vulnerability and Liver Waitlisting and Transplantation of Cirrhosis Patients

• P. Polineni{1}, A. A. Huang{1}, R. Huang{1}, B. J. Hasjim{1}, K. Guo{1}, L. Zhao{1}, A. Furmanchuk{1}, M. M. Dehchesmeh{2}, M. W. Lewis-Thames{1}, L. M. McElroy{3}, D. C. Simpson{1}, S. Mehrotra{2}, L. B. VanWagner{4}, D. P. Ladner{1}, {1}Northwestern University Feinberg School of Medicine, Chicago, IL, {2}Northwestern University, Evanston, IL, {3}Duke University Medical Center, Durham, NC, {4}UT Southwestern Medical Center, Dallas, TX

Use of the Claims-Based Frailty Index for Pre-Transplant Mortality in Cirrhosis Patients with Low MELD-Na

• A. A. Huang{1}, S. L. Olson{1}, A. J. Thuluvath{1}, P. Polineni{1}, B. J. Hasjim{1}, A. M. Flores{1}, A. Duarte-Rojo{1}, J. Doll{1}, T. Banea{1}, S. Mehrotra{2}, D. P. Ladner{1}, {1}Northwestern University Feinberg School of Medicine, Chicago, IL, {2}Northwestern University, Evanston, IL

Where You Live Matters: Patients with Cirrhosis Living in More Deprived Neighborhoods are Associated with Lower Survival and Transplant Wait listing

• B. J. Hasjim{1}, A. A. Huang{1}, P. Polineni{1}, A. Harris{1}, M. M. Dehchesmeh{2}, M. Paukner{1}, K. N. Kershaw{1}, T. Banea{1}, L. B. VanWagner{3}, S. Mehrotra{2}, L. Zhao{1}, D. P. Ladner{1}, {1}Northwestern University Feinberg School of Medicine, Chicago, IL, {2}Northwestern University, Evanston, IL, {3}UT Southwestern Medical Center, Dallas, TX

Double Lung Transplant REgistry Aimed for Lung-Limited Malignancies (DREAM) - A Prospective Registry Study for Double Lung Transplantation for Medically Refractory Cancers Limited to the Lungs

• Y. Chae, L. Chung, R. Tomic, A. Bharat, Northwestern University, Chicago, IL

Support Needs for Living Kidney Donor Candidates: Results from a Multicenter Qualitative Study

• A. Daley{1}, E. Alagoz{1}, J. Gannon{2}, S. Li{2}, D. Dobosz{2}, K. Kennedy{3}, D. Gray{4}, A. Mussell{4}, P. Reese{4}, E. Gordon{3}, S. Kulkarni{2}, C. Thiessen{1}, {1}University of Wisconsin, Madison, WI, {2}Yale University, New Haven, CT, {3}Northwestern University, Chicago, IL, {4}University of Pennsylvania, Philadelphia, PA

The First 58 Global Kidney Exchange Transplants: Overcoming Multiple Barriers to Transplantation

• M. Rees{1}, I. Marino{2}, A. A. Alobaidli{3}, S. Paloyo{4}, R. Sung{5}, A. Cohen{6}, L. BASAGOITIA GONZALEZ{7}, F. Citterio{8}, A. Roth{9}, O. Ekwenna{1}, J. R. Leventhal{10}, J. Hawksworth{11}, M. Ellis{12}, K. Krawiec{13}, T. Dunn{14}, {1}University of Toledo, Toledo, OH, {2}Jefferson, Roma, Italy, {3}Abu Dhabi Health Services Company, Abu Dhabi, United Arab Emirates, {4}Philippine General Hospital, Manila, Philippines, {5}University of Michigan Health System, Ann Arbor, MI, {6}Ochsner Health System, New Orleans, LA, {7}Pro Renal, Mexico City, Mexico, {8}Gemelli Hospital, Rome, Italy, {9}Standford University, Standford, CA, {10}SURGERY, Northwestern Medicine, Chicago, IL, {11}Walter Reed National Military Medical Center, Washington DC, DC, {12}Duke University Hospital, Durham, NC, {13}University of Virginia School of Law, Charlottesville, VA, {14}Hospital of the University of Pennsylvania, Philadelphia, PA

Cell-Free DNA Derived Temporal Dynamics and Trends of Torque Teno Virus in Kidney Transplant

• R. Sinha{1}, Z. Zhu{2}, J. Friedewald{3}, S. Kleiboeker{2}, {1}R&D, Viracor-Eurofins, Lenexa, KS, {2}Eurofins Viracor, Lenexa, KS, {3}Northwestern University, Chicago, IL

Do Hispanic Patients Complete Kidney Transplant Evaluation as Fast as Non-Hispanic White Patients?

• E. J. Gordon{1}, J. Lee{2}, R. Kang{2}, J. Uriarte{2}, J. Caicedo{2}, {1}Vanderbilt University Medical Center, Nashville, TN, {2}Northwestern University Feinberg School of Medicine, Chicago, IL

Expanding Donor Cause of Death Designations Reflects Changing Donor Population and Utilization Practices

• M. Adjei{1}, S. Wisel{2}, T. Todo{2}, G. Voidonikolas{2}, I. Kim{2}, J. Steggerda{2}, D. Borja-Cacho{3}, {1}Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA, {2}Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA, {3}Department of Surgery, Northwestern Memorial Hospital, Chicago, IL

Trends in Marginal Donor Utilization in the United States Across Solid Organ Transplant

• J. A. Steggerda{1}, D. Borja-Cacho{2}, S. A. Wisel{1}, D. P. Ladner{2}, T. Todo{3}, P. Catarino{4}, I. K. Kim{5}, {1}Transplant Surgery, Cedars-Sinai Medical Center, Los Angeles, CA, {2}Transplant Surgery, Northwestern Memorial Hospital, Chicago, IL, {3}Transplant Surgery, Cedars Sinai Medical Center, Los Angeles, CA, {4}Cardiothoracic Surgery, Cedars-Sinai Medical Center, Los Angeles, CA, {5}Transplant Surgery, Cedars-Sinai Medical Center, Los Angeles, Los Angeles, CA

Where Do Ethnic Disparities Arise in the Living Kidney Donor Evaluation Process?

• J. Uriarte{1}, S. Dong{1}, J. Lee{1}, R. Kang{1}, J. Figueroa{1}, J. Caicedo{1}, E. J. Gordon{2}, {1}Northwestern University Feinberg School of Medicine, Chicago, IL, {2}Vanderbilt University Medical Center, Nashville, IL

Association Between Hla Molecular Mismatch and Histological Rejection in Kidney Allograft

• M. Patel{1}, C. Rebello{2}, T. Whisenant{3}, K. Guo{2}, A. Tambur{2}, L. Zhao{2}, J. Friedewald{2}, S. Park{4}, {1}New York Institute of Technology College of Osteopathic Medicine, Old Westbury, NY, {2}Northwestern University, Chicago, IL, {3}University of California, San Diego, CA, {4}Northwestern University, CHICAGO, IL

Long-Term Outcomes of Conversion from Tacrolimus to Sirolimus in Kidney Transplant Recipients: An 8-Year Follow Up Study

• I. Tawhari{1}, S. Park{2}, F. Yamani{2}, A. Irshad{2}, L. Safar Boueri{2}, J. Ansari{2}, L. Gallon{2}, {1}King Khalid University, Abha, Saudi Arabia, {2}Northwestern University, Chicago, IL

Open Simultaneous Offers for High-KDRI Kidneys May Significantly Reduce Discards

• V. Kilambi{1}, M. Barah{2}, S. Dey{2}, S. Mehrotra{2}, {1}RAND Corporation, Arlington, VA, {2}Northwestern University, Evanston, IL

Polyclonal Treg Therapy for Renal Allograft Inflammation: Results of CTOT-21, A Randomized Controlled Clinical Trial

• S. Chandran{1}, Q. Tang{1}, J. C. Leung{1}, Z. Laszik{1}, B. Armstrong{2}, M. Morsheimer{3}, E. Farkash{4}, R. B. Mannon{5}, S. Davis{6}, J. Friedewald{7}, F. Vincenti{1}, {1}UCSF, San Francisco, CA, {2}Rho, Durham, NC, {3}DAIT, NIAID, Bethesda, MD, {4}U of Michigan, Ann Arbor, MI, {5}U of Nebraska, Omaha, NE, {6}U of Colorado, Denver, CO, {7}Northwestern U, Chicago, IL

Sodium Polystyrene Sulfonate vs Sodium Zirconium Cyclosilicate for Hyperkalemia in Abdominal Transplant Recipients

• C. Donnell{1}, L. Chargualaf{2}, A. Prom{3}, J. M. Trexler{2}, K. R. Szempruch{2}, {1}UNC Eshelman School of Pharmacy, Chapel Hill, NC, {2}UNC Medical Center, Chapel Hill, NC, {3}Northwestern Medicine, Chicago, IL

Transplant Centers Kidney Acceptance Rates Vary Even After Risk Adjusting for Donor and Kidney Characteristics as Well as Cold Time at Offer

• S. Dey{1}, M. Barah{2}, V. Kilambi{3}, S. Mehrotra{1}, {1}Northwestern University, Evanston, IL, {2}Northwestern University, Northwestern University, IL, {3}RAND Corporation, Arlington, VA

Posoleucel for BKV Infection in Kidney Transplant Patients: Final Results from Randomized, Placebo-Controlled Phase 2 Trial

• A. Chandraker{1}, A. Regmi{2}, R. Gohh{3}, A. Sharma{4}, S. E. Woodle{5}, M. J. Ansari{6}, V. Nair{7}, L. Chen{8}, T. Alhamad{9}, S. Norman{10}, F. Cardarelli{11}, J. Ma{11}, S. Gilmore{11}, S. Vasileiou{11}, D. Wojciechowski{12}, {1}Brigham and Women's Hospital, Boston, MA, {2}Inova Transplant Center, Falls Church, VA, {3}Rhode Island Hospital, Providence, RI, {4}University of Pittsburg Medical Center, Pittsburgh, PA, {5}University of Cincinnati, Cincinnati, OH, {6}Northwestern University, Chicago, IL, {7}Northwell Health, New Hyde Park, NY, {8}UC Davis Transplant Center, Sacramento, CA, {9}Washington University School of Medicine at St. Louis, Saint Louis, MO, {10}University of Michigan, Ann Arbor, MI, {11}AlloVir, Waltham, MA, {12}University of Texas Southwestern Medical Center, Dallas, TX

Hypothermic Oxygenated Machine Perfusion (HMP-O2) in Liver Transplantation: The PilotTM Experience

G. Panayotova{1}, A. Rana{2}, R. C. Quillin III{3}, K. Lunsford{4}, V. Agopian{5}, D. Markovic{5}, Y. Qin{4}, F. Paterno{4}, A. Amin{4}, G. Lee-Riddle{4}, A. Griesemer{6}, D. Alonso{7}, J. Rocca{8}, D. Borja-Cacho{9}, R. Hernandez-Alejandro{10}, J. Fung{11}, S. Pelletier{12}, S. Shah{13}, J. Guarrera{14}, {1}Surgery, Rutgers NJMS, Newark, NJ, {2}Baylor University, Missouri City, TX, {3}University of Cincinnati College of Medicine, Cincinnati, OH, {4}Rutgers New Jersey Medical School, Newark, NJ, {5}UCLA School of Medicine, LA, CA, {6}Columbia University Medical Center, New York, NY, {7}Intermountain Medical Center, Murray, UT, {8}Montefiore Medical Center, New York, NY, {9}Northwestern University Medical Center, Chicago, IL, {10}University of Rochester Medical Center, Rochester, NY, {11}University of Chicago Medical Center, Chicago, IL, {12}University of Virginia Health System, Charlottesville, VA, {13}University of Cincinnati, Cincinnati, OH, {14}Surgery/ Transplant, Rutgers New Jersey Medical School, Newark, NJ

Impact of Desensitization Therapy with Isatuximab on Circulating HLA-Specific Memory B Cells in Highly Sensitized Patients Waitlisted for Kidney Transplantation

• A. Torija{1}, D. Kervella{1}, L. Donadeu{1}, M. Meneghini{1}, E. Crespo{1}, F. Moreso{1}, J. Cruzado{2}, R. Buchli{3}, F. Vincenti{4}, A. Brar{4}, A. Tambur{5}, M. Stegall{6}, H. Lee{7}, M. Dudek{7}, G. Abbadessa{8}, O. Bestard{1}, {1}Translational Transplant Center, Vall D'Hebron University Hospital, Barcelona, Spain, {2}Bellvitge University Hospital, Barcelona, Spain, {3}Pure Protein, LLC, Oklahoma City, OK, {4}University of California San Francisco, San Francisco, CA, {5}Northwestern University, Chicago, IL, {6}Mayo Clinic, Rochester, MN, {7}Sanofi, Cambridge, MA, {8}Sanofi, Cambrige, MA

Safety and Efficacy of Kidney Transplantation from Donors with HIV to Recipients with HIV: Results of the Multicenter Hope in Action Study

• C. Durand{1}, S. Florman{2}, T. Liang{3}, M. Rana{2}, R. Friedman-Moraco{4}, A. Gilbert{5}, P. Stock{6}, S. Mehta{7}, S. A. Mehta{8}, V. Stosor{9}, M. Pereira{10}, M. Morris{11}, J. Hand{12}, J. Schaenman{13}, S. Aslam{14}, M. Malinis{15}, G. Haidar{16}, C. Small{17}, C. Santos{18}, J. Baddley{19}, E. Blumberg{20}, D. Wojciechowski{21}, N. Elias{22}, S. Apewokin{23}, D. Brown{3}, N. Desai{3}, J. Odim{24}, A. Tobian{3}, A. Massie{8}, D. Segev{8}, {1}Medicine, JHU, BALTIMORE, MD, {2}Sinai, NYC, NY, {3}JHU, Baltimore, MD, {4}Emory, Atlanta, GA, {5}Georgetown, Washington, DC, {6}UCSF, San Francisco, CA, {7}UAB, Birmingham, AL, {8}NYU, NYC, NY, {9}Northwestern, Chicago, IL, {10}Columbia, NYC, NY, {11}Univ of Miami, Miami, FL, {12}Ochsner, New Orleans, LA, {13}UCLA, LA, CA, {14}UCSD, San Diego, CA, {15}Yale, New Haven, CT, {16}UPMC, Pittsburgh, PA, {17}Cornell, NYC, NY, {18}Rush, Chicago, IL, {19}UMD, Baltimore, MD, {20}UPenn, Philadelphia, PA, {21}UTSW, Dallas, TX, {22}MGH, Boston, MA, {23}Univ of Chicago, Chicago, IL, {24}NIH, Bethesda, MD

Alemtuzumab vs. Anti-Thymocyte Globulin in Kidney Transplant Recipients Receiving a Steroid Free Maintenance Regimen

• R. Rikard{1}, L. Chargualaf{1}, A. Prom{2}, C. Coulter{1}, E. Weimer{1}, J. Schmitz{1}, E. Kotzen{1}, K. Szempruch{1}, {1}UNC Health, Chapel Hill, NC, {2}Northwestern Memorial Hospital, Chicago, IL

Association of HLA Eplet Mismatch with Positive Gene Expression and dd-cfDNA Biomarkers in Kidney Transplant Recipients 

• A. Ahmed{1}, B. Kinsella{2}, C. Rebello{2}, K. Guo{2}, S. Park{2}, T. Whisenant{3}, J. Friedewald{2}, {1}Chicago Medical School at Rosalind Franklin University, Chicago, IL, {2}Northwestern University, Chicago, IL, {3}UCSD, San Diego, CA

How Do IRB Members and Ethicists Assess the Risk of Zoonotic Disease Transmission in Xenotransplant Pig Kidney Clinical Trials?

• M. M. Matthews{1}, E. J. Gordon{2}, M. K. Gusmano{3}, J. Gacki-Smith{4}, K. Traboulsi{3}, J. J. Uriarte{4}, D. Manning{4}, J. Leventhal{5}, K. J. Maschke{6}, {1}The Hastings Center, Brooklyn, NY, {2}Vanderbilt University, Nashville, TN, {3}Lehigh University, Bethelham, PA, {4}Northwestern Univeristy, Chicago, IL, {5}Northwestern Medicine, Chicago, IL, {6}The Hastings Center, Garrison, NY

Modeling of Non-Alcoholic Steatohepatitis Ex-Vivo Using Hepatocyte-Like Cells Differentiated from Human Induced Pluripotent Stem Cells

• E. Minocha{1}, A. Kumar Gupta{1}, A. Benintende{2}, J. Purdy{1}, R. Green{2}, J. A. Wertheim{1}, {1}University of Arizona College of Medicine - Tucson, Tucson, AZ, {2}Northwestern University Feinberg School of Medicine, Chicago, IL

Potential Living Kidney Donors’ Concerns About Opting Out and Preferences for an Alibi: Results from a Multicenter Study

• K. Yu{1}, J. Gannon{2}, S. Li{2}, D. Dobosz{2}, K. Kennedy{3}, D. Gray{4}, A. Mussell{4}, P. Reese{4}, E. Gordon{3}, S. Kulkarni{2}, C. Thiessen{5}, {1}Columbia University, New York, NY, {2}Yale U, New Haven, CT, {3}Northwestern U, Chicago, IL, {4}U Pennsylvania, Philadelphia, PA, {5}UW Madison, Madison, WI

Who Should Participate in First-In-Human Pig Xenotransplant Clinical Trials?

• M. K. Gusmano{1}, K. Maschke{2}, J. Gacki-Smith{3}, M. Matthews{2}, K. Traboulsi{4}, D. Manning{3}, J. Uriarte{3}, J. Leventhal{5}, E. J. Gordon{6}, {1}College of Health, Lehigh University, Bethlehem, PA, {2}The Hastings Center, Garrison, NY, {3}Northwestern University, Chicago, IL, {4}Lehigh University, Bethlehem, PA, {5}Northwestern Medicine, Chicago, IL, {6}Surgery, Northwestern University Feinberg School of Medicine, Oak Park, IL

Clinical Application and Outcomes with Use of the Heart Organ Care System

•  J. Stehlik{1}, C. Milano{2}, S. Pinney{3}, C. Patel{4}, D. D'Alessandro{5}, R. P. Davis{6}, C. Maulion{6}, D. Goldstein{7}, U. Jorde{7}, J. Pal{8}, M. Daneshmand{9}, F. Esmailian{10}, J. A. Kobashigawa{11}, S. Pham{12}, P. Patel{12}, K. Takeda{13}, N. Uriel{13}, A. S. Shah{14}, M. Kai{15}, G. Couper{16}, A. Vest{16}, B. Sun{17}, L. Lozonschi{18}, M. Ono{19}, L. Klein{20}, D. T. Pham{21}, D. Joyce{22}, H. Mallidi{23}, M. R. Mehra{23}, M. Farr{24}, {1}University Of Utah School Of Medicine, Salt Lake City, UT, {2}Duke University, Durham, NC, {3}University of Chicago, Chicago, IL, {4}Duke University Med Ctr, Durham, NC, {5}Massachusetts General Hospital, Boston, MA, {6}Yale New Haven Hospital, New Haven, CT, {7}Montefiore Medical Center, Bronx, NY, {8}University of Washington Medical Center, Seattle, WA, {9}Emory University Hospital, Atlanta, GA, {10}Cedars-Sinai Medical Center, Los Angeles, CA, {11}Cedars-Sinai Smidt Heart Institute, Los Angeles, CA, {12}Mayo Clinic Florida, Jacksonville, FL, {13}New York Presbyterian Hospital, New York, NY, {14}Vanderbilt University Medical Center, Mount Juliet, TN, {15}Westchester Medical Center, Valhalla, NY, {16}Tufts Medical Center, Boston, MA, {17}Minneapolis Heart Institute, Minneapolis, MN, {18}Tampa General Hospital, Tampa, FL, {19}Methodist Specialty and Transplant Hospital, San Antonio, TX, {20}University of California San Francisco Medical Center, San Francisco, CA, {21}Northwestern Memorial Hospital, Chicago, IL, {22}Froedtert Memorial Lutheran Hospital, Milwaukee, WI, {23}Brigham and Womens Hospital, Boston, MA, {24}University of Texas Southwestern, Dallas, TX

Infections After Kidney Transplantation from Donors with Hiv to Recipients with Hiv: Results from the Multicenter Hope in Action Study

• W. Werbel{1}, T. Liang{2}, M. Rana{3}, S. Florman{3}, R. Friedman-Moraco{4}, A. Gilbert{5}, P. Stock{6}, S. Mehta{7}, H. Neumann{7}, S. Mehta{8}, V. Stosor{9}, M. Pereira{10}, M. Morris{11}, J. Hand{12}, J. Schaenman{13}, S. Aslam{14}, M. Malinis{15}, G. Haidar{16}, C. Small{17}, C. Santos{18}, J. Castillo-Lungo{19}, O. Adebiyi{20}, J. Baddley{21}, K. Ranganna{22}, E. Blumberg{23}, D. Wojciechowski{24}, J. Odim{25}, A. Massie{7}, D. Segev{7}, C. Durand{2}, {1}Johns Hopkins, Baltimore, MD, {2}J Hopkins, Baltimore, MD, {3}Mt. Sinai, NY, NY, {4}Emory, ATL, GA, {5}Georgetown, DC, DC, {6}UCSF, San Francisco, CA, {7}NYU, NY, NY, {8}UAB, Birmingham, AL, {9}Northwestern, CHI, IL, {10}Columbia, NYC, NY, {11}UMiami, Miami, FL, {12}Ochsner, New Orleans, LA, {13}UCLA, Los Angeles, CA, {14}UCSD, San Diego, CA, {15}Yale, New Haven, CT, {16}UPMC, Pittsburgh, PA, {17}Cornell, NY, NY, {18}Rush, CHI, IL, {19}Methodist, Dallas, TX, {20}Indiana U, Indianapolis, IN, {21}UMaryland, Baltimore, MD, {22}Drexel, PHL, PA, {23}UPenn, PHL, PA, {24}UTSW, Dallas, TX, {25}NIH, Bethesda, MD

Multiscale Genetic Architecture of Donor-Recipient Differences Reveals Intronic Lims1 Locus Mismatches Associated with Long-Term Renal Transplant Survival

• M. Menon{1}, Z. Zhang{2}, K. Banu{3}, I. Gibson{4}, R. Colvin{5}, Z. Yi{2}, W. Zhang{2}, L. Gallon{6}, P. O'Connell{7}, J. Pober{3}, P. Heeger{8}, M. Menon{3}, {1}Yale School of Medicine, New Haven, CT, {2}Icahn School of Medicine at Mount Sinai, New York City, NY, {3}Yale University School of Medicine, New Haven, CT, {4}Max Rady College of Medicine, Edmundston, MB, Canada, {5}Massachusetts General Hospital, Boston, MA, {6}Northwestern University NMFF, Chicago, IL, {7}University of Sydney, NSW, Australia, {8}Cedars-Sinai Medical Center, West Hollywood, CA

Defining the Minimal Clinically Important Differences in Physical Frailty Using the Liver Frailty Index in Patients with Cirrhosis Awaiting Liver Transplantation

• M. Wang{1}, A. Shui{1}, J. Ruck{2}, C. Huang{1}, E. Verna{3}, E. King{2}, D. P. Ladner{4}, D. Ganger{5}, M. Kappus{6}, R. S. Rahimi{7}, M. Volk{8}, A. Tevar{9}, A. Duarte{10}, J. C. Lai{1}, {1}University of California San Francisco, San Francisco, CA, {2}Johns Hopkins Hospital, Baltimore, MD, {3}Columbia University, New York, NY, {4}Northwestern Medicine, Chicago, IL, {5}Northwestern University, Chicago, IL, {6}Duke University, Raleigh, NC, {7}Baylor Scott and White Health, Dallas, TX, {8}Loma Linda University, Loma Linda, CA, {9}University of Pittsburgh Medical Center, Pittsburgh, PA, {10}Northwestern University, Chicago, IL

Indirect Evidence for Circulating Factors in Focal Segmental Glomerulosclerosis Via Molecular Analysis of Podocyte Injury in Kidney Organoids 

• A. K. Gupta{1}, E. Minocha{1}, A. Abu Maziad{1}, J. A. Wertheim{1}, L. G. Gallon{2}, {1}University of Arizona College of Medicine - Tucson, Tucson, AZ, {2}Northwestern University Feinberg School of Medicine, Chicago, IL

Longitudinal Evaluation of Immune Single Cell Transcriptome of Living Donor Kidney Transplant Recipients Tolerized with Allogeneic Stem Cell Therapy

• H. Zubair{1}, T. Rousselle{1}, A. Shetty{1}, S. Azim{1}, C. Suire{2}, J. R. Leventhal{3}, S. Ildstad{2}, V. Mas{1}, {1}Surgical Sciences, University of Maryland, Baltimore, MD, {2}Talaris Therapeutics, Louisville, KY, {3}Surgery, Northwestern Medicine, Chicago, IL

Predicting Evaluation Completion and Donation by Relationship Type: Identifying Opportunities for More Donors

• J. Daw{1}, A. Meinders{2}, J. D. Peipert{3}, E. Graviss{2}, D. T. Nguyen{2}, F. Weng{4}, A. Waterman{2}, {1}Pennsylvania State University, University Park, PA, {2}Houston Methodist Hospital, Houston, TX, {3}Northwestern University, Chicago, IL, {4}Saint Barnabas Medical Center, Livingston, NJ

Recovery of Physical Function (PF) After Kidney (KT) versus Liver (LT) Transplantation

• I. Mucsi{1}, N. Jain{2}, Y. Chien{2}, N. Edwards{2}, D. Lodge{2}, T. Patel{2}, A. Samudio{2}, D. Howell{3}, M. Li{4}, J. Peipert{5}, S. J. Bartlett{6}, N. Selzner{2}, {1}Toronto General Hospital, Toronto, ON, Canada, {2}University Health Network, Toronto, ON, Canada, {3}University of Toronto, Toronto, ON, Canada, {4}Princess Margaret Cancer Center, Toronto, ON, Canada, {5}Northwestern University, Chicago, IL, {6}McGill University, Montreal, QC, Canada

Social Participation in Kidney Transplant Recipients (KT) Compared to Patients on Hemodialysis (HD)

• I. Mucsi{1}, M. Siddiqui{2}, J. Wang{2}, J. Kalaher{2}, V. Baltazar{2}, L. Kerr{2}, A. Sampathu{2}, J. Peipert{3}, S. J. Bartlett{4}, M. Li{5}, D. Howell{6}, M. Novak{6}, {1}Toronto General Hospital, Toronto, ON, Canada, {2}University Health Network, Toronto, ON, Canada, {3}Northwestern University, Chicago, IL, {4}McGill University, Montreal, QC, Canada, {5}Princess Margaret Cancer Center, Toronto, ON, Canada, {6}University of Toronto, Toronto, ON, Canada

Understanding Humanistic Motivations of Potential Living Donors Who Are Friends and Acquaintances Compared to Family Members

• A. M. Meinders{1}, J. Daw{2}, J. D. Peipert{3}, E. A. Graviss{1}, D. T. Nguyen{1}, F. Weng{4}, A. Waterman{1}, {1}Houston Methodist Hospital, Houston, TX, {2}The Pennsylvania State University, University Park, PA, {3}Northwestern University, Chicago, IL, {4}Saint Barnabas Medical Center, Livingston, NJ

What Information Do Kidney Transplant Candidates Need to Make Informed Treatment Decisions About Participating in a First-In-Human Pig Xenotransplant Clinical Trial? 

• E. J. Gordon{1}, K. Maschke{2}, J. Gacki-Smith{3}, M. Matthews{2}, K. Traboulsi{4}, D. Manning{3}, J. Uriarte{3}, J. Leventhal{5}, M. Gusmano{4}, {1}Vanderbilt University Medical Center, Nashville, TN, {2}The Hastings Center, Garrison, NY, {3}Northwestern University Feinberg School of Medicine, Chicago, IL, {4}Lehigh University, Bethlehem, PA, {5}Northwestern Medicine, Chicago, IL

Would Kidney Transplant Candidates Participate in a First-In-Human Pig Xenotransplant Clinical Trial?

• E. J. Gordon{1}, M. Gusmano{2}, J. Gacki-Smith{3}, M. Matthews{4}, K. Traboulsi{2}, D. Manning{3}, J. Uriarte{3}, J. Leventhal{5}, K. Maschke{4}, {1}Vanderbilt University Medical Center, Nashville, TN, {2}Lehigh University, Bethlehem, PA, {3}Northwestern University Feinberg School of Medicine, Chicago, IL, {4}The Hastings Center, Garrison, NY, {5}Northwestern Medicine, Chicago, IL

Polyclonal Treg Therapy for Renal Allograft Inflammation: Results of CTOT-21, A Randomized Controlled Clinical Trial

• S. Chandran{1}, Q. Tang{1}, J. C. Leung{1}, Z. Laszik{1}, B. Armstrong{2}, M. Morsheimer{3}, E. Farkash{4}, R. B. Mannon{5}, S. Davis{6}, J. Friedewald{7}, F. Vincenti{1}, {1}UCSF, San Francisco, CA, {2}Rho, Durham, NC, {3}DAIT, NIAID, Bethesda, MD, {4}U of Michigan, Ann Arbor, MI, {5}U of Nebraska, Omaha, NE, {6}U of Colorado, Denver, CO, {7}Northwestern U, Chicago, IL

Maintenance of Lung Graft Tolerance is Dependent on Continuous Recruitment of Foxp3+ Cells to Allografts

• Y. Bai{1}, W. Li{1}, Y. Terada{1}, H. M. Shepherd{1}, J. M. Gauthier{1}, Y. Yokoyama{1}, A. Bery{1}, A. Alessandrini{2}, P. T. Sage{3}, A. Bharat{4}, R. G. Nava{1}, A. S. Krupnick{5}, A. E. Gelman{1}, K. J. Lavine{1}, D. Kreisel{1}, {1}Washington University in St. Louis, St. Louis, MO, {2}Massachusetts General Hospital, Boston, MA, {3}Brigham and Women's Hospital, Boston, MA, {4}Northwestern University, Chicago, IL, {5}University of Maryland, Baltimore, MD

Wait Time Advantage for Transplant Candidates with HIV Who Accept Kidneys from Donors with HIV

• J. D. Motter{1}, S. Hussain{2}, S. Florman{3}, M. Rana{3}, R. Friedman-Moraco{4}, A. Gilbert{5}, P. Stock{6}, S. Mehta{7}, S. A. Mehta{1}, V. Stosor{8}, N. Elias{9}, M. Pereira{10}, G. Haidar{11}, M. Malinis{12}, M. Morris{13}, J. Hand{14}, S. Aslam{15}, J. Schaenman{16}, J. Baddley{17}, C. Small{18}, D. Wojciechowski{19}, E. F. Hollinger{20}, E. Blumberg{21}, J. Odim{22}, S. Apewokin{23}, E. Giorgakis{24}, A. Tobian{2}, D. Segev{1}, A. B. Massie{1}, C. M. Durand{2}, {1}NYU, New York, NY, {2}JHU, Baltimore, MD, {3}Mt Sinai, New York, NY, {4}Emory, Atlanta, GA, {5}Medstar Georgetown, Washington, DC, {6}UCSF, San Francisco, CA, {7}UAB, Birmingham, AL, {8}Northwestern, Chicago, IL, {9}MGH, Milton, MA, {10}Columbia, New York, NY, {11}UPMC, Pittsburgh, PA, {12}Yale, New Haven, CT, {13}University of Miami, Miami, FL, {14}Ochsner, New Orleans, LA, {15}UCSD, San Diego, CA, {16}UCLA, Los Angeles, CA, {17}UMD, Baltimore, MD, {18}Weill Cornell, New York, NY, {19}UT SW, Dallas, TX, {20}Rush, Chicago, IL, {21}UPenn, Philadelphia, PA, {22}NIAID, Bethesda, MD, {23}University of Cincinnati, Cincinnati, OH, {24}UAMS, Little Rock, AR

Treg Modulation with CD28 and IL-6 Receptor Antagonists in Kidney Transplant Recipients: Results of CTOT-24, a Prospective Clinical Trial

• S. Chandran{1}, Q. Tang{1}, J. Leung{1}, B. Armstrong{2}, J. Friedewald{3}, A. Kirk{4}, M. Morsheimer{5}, F. Vincenti{1}, {1}UCSF, San Francisco, CA, {2}Rho, Durham, NC, {3}Northwestern U, Chicago, IL, {4}Duke U, Durham, NC, {5}NIAID, Bethesda, MD