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Northwestern University Feinberg School of Medicine
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Breakthroughs Podcast

Listen to the people behind the science

Northwestern University Feinberg School of Medicine is a research-intensive medical school that fosters powerful collaborations on a thriving academic medical campus. We are driven by our mission to transform the practice of medicine and profoundly impact human health beyond the individual patient. We believe better answers only come from discovery.

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Cover image for episode 39

The Urgent Need for New Uterine Fibroid Treatments with Serdar Bulun, MD

It is the most common tumor found in women and is the cause of 200,000 hysterectomies in the United States every year. Yet, uterine fibroids have not been a frequent topic of medical research. Northwestern’s Serdar Bulun, MD, leads one of the few research programs focused on the molecular and cellular abnormalities that may cause uterine fibroids and is investigating novel targets to treat the condition.
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What Drives Female Resident Burnout Rates? with Karl Bilimoria, MD & Yue-Yung Hu, MD

In recent Northwestern Medicine study, published in the New England Journal of Medicine, women surgical residents reported more mistreatment than men, which was linked to higher burnout rates and more suicidal thoughts.
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The Future of Genetic Medicine with Elizabeth McNally, MD, PhD

Dr. Elizabeth McNally is a human geneticist, a Northwestern Medicine cardiologist and the director of the Center for Genetic Medicine at Northwestern. In this episode, she talks about her recent discoveries in the genetics of cardiovascular and neuromuscular disorders and shares what we can expect in the next few years in the field of genetic medicine.
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Treating Aggressive Prostate Cancer with Maha Hussain, MD

For those with advanced metastatic prostate cancer, treatments are limited, but a new Phase 3 international clinical trial shows that a genetic targeted therapy could offer new hope for patients with specific gene mutations in their tumors. Northwestern's Dr. Maha Hussain recently presented the results of this landmark trial and shares insight.
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Epigenetics and Cancer with Ali Shilatifard, PhD

For more than two decades, Ali Shilatifard, PhD, has dedicated his career to revealing the causes of childhood leukemia and providing detailed molecular insight into the role of epigenetics in cancer. He hopes his discoveries will lead to a super drug that could end childhood leukemia and other cancers.
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Investigating New Glioblastoma Therapies with Rimas Lukas, MD

Northwestern scientists are conducting dozens of experiments and clinical trials aimed at understanding and fighting glioblastoma, the most common and aggressive primary brain tumor in adults. Rimas Lukas, MD, shares results of a promising Phase 1 clinical trial and other projects underway.
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Artificial Intelligence and Medicine with Mozziyar Etemadi, MD, PhD

Mozziyar Etemadi, MD, PhD, a research assistant professor in Anesthesiology and Biomedical Engineering is leading deep learning projects in his lab at Northwestern. He talks about a collaboration between Northwestern and Google that uses a deep learning system to predict lung cancer.
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Bioengineered Organs and Kidney Diseases with Susan Quaggin, MD

In the new Louis A. Simpson and Kimberly K. Querrey Biomedical Research Center at Northwestern, tiny bio-artificial kidneys are growing in the lab of Dr. Susan Quaggin. She and a team of scientists, with expertise in stem cells, blood vessels and developmental biology, are accelerating the development of such bioengineered organs. But that’s not all. Dr. Quaggin talks about the projects and science underway that could lead to new treatments to prevent, manage and cure kidney diseases.
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Changes to Endometrial Cancer Treatment with Daniela Matei, MD

Results from a randomized phase three clinical trial published in The New England Journal of Medicine could change the way women are treated for later stage endometrial cancer. Northwestern's Dr. Daniela Matei led the trial and is here with details. 
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Heart Failure Deaths on the Rise in Younger People with Sadiya Khan, MD, MSc

Death rates due to heart failure are increasing, especially in people under the age of 65 and specifically among Black men. What is fueling this upturn? How can it be stopped? Sadiya Khan, MD, assistant professor of medicine explains.
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Improving Memory Loss in Older Adults with Joel Voss, PhD

As we age, almost all of us have some memory loss. This age-related affliction is normal, but a new Northwestern Medicine study suggests it can be improved with non-invasive brain stimulation that sends electromagnetic pulses into a specific area of the brain. Joel Voss, PhD, an associate professor at Northwestern, led this study, published in the journal Neurology.
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Eyes May Reveal Risk of Alzheimer’s Disease with Amani Fawzi, MD

A new approach from the field of ophthalmology shows promise in detecting non-invasive biomarkers of mild cognitive impairment, the precursor to Alzheimer’s disease. Northwestern's Amani Fawzi, MD, explains.
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New Evidence on Eggs and Heart Health with Norrina Allen, PhD

A large, new Northwestern Medicine study reports adults who ate more eggs and dietary cholesterol had a significantly higher risk of cardiovascular disease and death from any cause. Norrina Allen, associate professor of preventive medicine at Northwestern University Feinberg School of Medicine, explains.
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Serious Eczema Symptoms Beyond the Skin with Jonathan Silverberg, MD, PhD, MPH

The health issues facing people with severe eczema are not only skin deep. Aside from intense itching and dry, irritable skin, people with a type of eczema known as atopic dermatitis also have significantly higher rates of medical and mental health issues. Why does atopic dermatitis come with so many other health issues and what can be done to give patients relief? Northwestern's Dr. Jonathan Silverberg explains.  
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Going Wireless in the NICU with John A. Rogers, PhD and Amy Paller, MD

Northwestern’s John A. Rogers, PhD, and Amy Paller, MD, published a study in the journal Science that shows how ultra thin, electronic sensors developed in Roger’s lab have the potential to make NICUs wireless.
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Children in the Juvenile Justice System Face Serious Health Risks with Linda Teplin, PhD

The landmark Northwestern Juvenile Project, led by Linda Teplin, PhD, has produced some astonishing findings about health risks and premature deaths of delinquent youth. These findings are shaping services and programs that support juvenile detainees, giving them the help they need to live healthier lives.
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Why Are Food Allergies on the Rise? with Ruchi Gupta, MD

There’s been an uptick in childhood food allergies in recent years, and new evidence from Northwestern shows that they’re also becoming more common in adults. Many of the reactions to these allergies are life-threatening. Why is this increase happening and how can we keep people affected by food allergy safe? Ruchi Gupta, MD, MPH is trying to answer those questions.
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Finding the Internal Fountain of Youth in Amish Country with Douglas Vaughan, MD

A rare blood disorder related to people missing a protein, called PAI-1, was identified in a small Amish community. Douglas Vaughan, MD, studies the community and found that those without the protein seem to live longer and healthier lives.
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Your Ideal Heart Health with Donald Lloyd-Jones, MD, ScM

Dr. Donald Lloyd-Jones was named physician of the year in 2017 by the American Heart Association. Through his research and practice as a preventive cardiologist at Northwestern, Dr. Lloyd Jones is chasing a big goal – to improve and preserve the heart health of Americans, one patient at a time.
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Cover image for episode 19

The Genetics of Coffee Drinkers with Marilyn Cornelis, PhD

Is drinking coffee a healthy habit or a vice? Why can some people drink coffee all day with little consequence while others get jittery after a cup? Marilyn Cornelis, PhD, studies the genetics of coffee consumption, caffeine metabolism and taste preferences and has some new findings to share about one of the most popular beverages in the world.
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Precision Medicine for African-Americans with Minoli Perera, PharmD, PhD

The field of pharmacogenomics -- using a patient’s genome to predict how well they will respond to medication -- is a hot area of medicine today. But, almost all data used in these predictions comes from people of European decent. Minoli Perera, PharmD, PhD, wants to change that. She is a pioneer in the area of pharmacogenomics in African-Americans and has some new discoveries to share.
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Continuing Medical Education Credit

Physicians who listen to this podcast may claim continuing medical education credit after listening to an episode of this program.

Target Audience

Academic/Research, Multiple specialties

Learning Objectives

At the conclusion of this activity, participants will be able to:

  1. Identify the research interests and initiatives of Feinberg faculty.
  2. Discuss new updates in clinical and translational research.
Accreditation Statement

The Northwestern University Feinberg School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit Designation Statement

The Northwestern University Feinberg School of Medicine designates this Enduring Material for a maximum of 0.5 AMA PRA Category 1 Credit(s)™.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

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