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Northwestern University Feinberg School of Medicine
Research

High-Impact-Factor Research 2020

Arabkheradmand G, Zhou G, Noto T, Yang Q, Schuele SU, Parvizi J, Gottfried JA, Wu S, Rosenow JM, Koubeissi MZ, Lane G, Zelano C.Anticipation-induced delta phase reset improves human olfactory perception. PLoS Biology. 2020;18(5):e3000724.

Azad HA, Monuteaux MC, Rees CA, Siegel M, Mannix RC, Lee LK, Sheehan KM, Fleegler EW. Child Access Prevention Firearm Laws and Firearm Fatalities Among Children Aged 0 to 14 Years, 1991-2016. Jama Pediatrics. 2020;174(5):463-469.

Balte P, Chaves PHM, Couper DJ, Enright P, Jacobs DR, Kalhan R, Kronmal RA, Loehr LR, London S, Newman AB, O'Connor GT, Schwartz JE, Smith BM, Smith L, White WB, Yende S, Oelsner EC. Association of Nonobstructive Chronic Bronchitis With Respiratory Health Outcomes in Adults. Jama Internal Medicine. 2020;180(5):676-686.

Beguelin W, Teater M, Meydan C, Hoehn KB, Phillip JM, Soshnev AA, Venturutti L, Rivas MA, Calvo-Fernandez MT, Gutierrez J, Camarillo JM, Takata K, Tarte K, Kelleher NL, Steidl C, Mason CE, Elemento O, Allis CD, Kleinstein SH, Melnick AM. Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response. Cancer Cell. 2020;37(5):655.

Du Y, Hultquist JF, Zhou Q, Olson A, Tseng Y, Zhang TH, Hong M, Tang K, Chen L, Meng X, McGregor MJ, Dai L, Gong D, Martin-Sancho L, Chanda S, Li X, Bensenger S, Krogan NJ, Sun R. mRNA display with library of even-distribution reveals cellular interactors of influenza virus NS1. Nature Communications. 2020;11(1):2449.

Freitag TL, Podojil JR, Pearson RM, Fokta FJ, Sahl C, Messing M, Andersson LC, Leskinen K, Saavalainen P, Hoover LI, Huang K, Phippard D, Maleki S, King NJC, Shea LD, Miller SD, Meri SK, Getts DR. Gliadin Nanoparticles Induce Immune Tolerance to Gliadin in Mouse Models of Celiac Disease. Gastroenterology. 2020;158(6):1667.

Hirano I, Chan ES, Rank MA, Sharaf RN, Stollman NH, Stukus DR, Wang K, Greenhawt M, Falck-Ytter YT, Comm AGAICG, Joint Task Force A-I. AGA Institute and the Joint Task Force on Allergy -Immunology Practice Parameters Clinical Guidelines for the Management of Eosinophilic Esophagitis. Gastroenterology. 2020;158(6):1776-1786.

Jin HB, Du Z, Zhang YJ, Antal JD, Xia ZL, Wang Y, Gao Y, Zhao XG, Han XY, Cheng YJ, Shen QH, Zhang KP, Elder RE, Benko Z, Fenyvuesvolgyi C, Li G, Rebello D, Li J, Bao SL, Zhao RY, Wang DW. A distinct class of plant and animal viral proteins that disrupt mitosis by directly interrupting the mitotic entry switch Wee1-Cdc25-Cdk1. Science Advances. 2020;6(20):15.

Krist AH, Davidson KW, Mangione CM, Barry MJ, Cabana M, Caughey AB, Donahue K, Doubeni CA, Epling JW, Jr., Kubik M, Ogedegbe G, Pbert L, Silverstein M, Simon MA, Tseng CW, Wong JB. et al. (including Simon M). Primary Care-Based Interventions to Prevent Illicit Drug Use in Children, Adolescents, and Young Adults: US Preventive Services Task Force Recommendation Statement. JAMA 2020;323(20):2060-2066.

Lee P, Chandel NS, Simon MC. Cellular adaptation to hypoxia through hypoxia inducible factors and beyond. Nature Reviews Molecular Cell Biology. 2020;21(5):268-283.

Penedo FJ, Oswald LB, Kronenfeld JP, Garcia SF, Cella D, Yanez B. The increasing value of eHealth in the delivery of patient-centred cancer care. Lancet Oncology. 2020;21(5):e240-e251.

Sala AJ, Bott LC, Brielmann RM, Morimoto RI.Embryo integrity regulates maternal proteostasis and stress resilience. Genes and Development. 2020;34(9-10):678-687.

Sonoda T, Li JY, Hayes NW, Chan JC, Okabe Y, Belin S, Nawabi H, Schmidt TM. A noncanonical inhibitory circuit dampens behavioral sensitivity to light. Science. 2020;368(6490):527.

Vien TN, Wang JL, Ng LCT, Cao E, DeCaen PG. Molecular dysregulation of ciliary polycystin-2 channels caused by variants in the TOP domain. Proceedings of the National Academy of Sciences of the United States of America. 2020;117(19):10329-10338.

Wang S, Park SS, Buru CT, Lin H, Chen PC, Roth EW, Farha OK, Mirkin CA. Colloidal crystal engineering with metal-organic framework nanoparticles and DNA. Nature Communications. 2020;11(1):2495.

Zhang YN, Wang YJ, Gao BX, Sun YQ, Cao L, Genardi SM, Wang CR, Li HB, Sun ZL, Yang YJ, Fang DY. USP22 controls iNKT immunity through MED1 suppression of histone H2A monoubiquitination. Journal of Experimental Medicine. 2020;217(5):17.

 

Alessandro C, Barroso FO, Prashara A, Tentler DP, Yeh HY, Tresch MC. Coordination amongst quadriceps muscles suggests neural regulation of internal joint stresses, not simplification of task performance. Proceedings of the National Academy of Sciences of the United States of America. 2020;117(14):8135-8142.

Aoi Y, Smith ER, Shah AP, Rendleman EJ, Marshall SA, Woodfin AR, Chen FX, Shiekhattar R, Shilatifard A. NELF Regulates a Promoter-Proximal Step Distinct from RNA Pol II Pause-Release. Molecular Cell. 2020;78(2):261-274.e265.

Baptista MAS, Merchant K, Barrett T, Bhargava S, Bryce DK, Ellis JM, Estrada AA, Fell MJ, Fiske BK, Fuji RN, Galatsis P, Henry AG, Hill S, Hirst W, Houle C, Kennedy ME, Liu X, Maddess ML, Markgraf C, Mei H, Meier WA, Needle E, Ploch S, Royer C, Rudolph K, Sharma AK, Stepan A, Steyn S, Trost C, Yin Z, Yu H, Wang X, Sherer TB. LRRK2 inhibitors induce reversible changes in nonhuman primate lungs without measurable pulmonary deficits. Science Translational Medicine. 2020;12(540).

Bayefsky MJ, Bartz D, Watson KL. Abortion during the Covid-19 Pandemic - Ensuring Access to an Essential Health Service. New England Journal of Medicine. 2020;382(19):e47.

Carnethon MR, Khan SS. A Feast of Observations About Diet. Circulation. 2020;141(14):1138-1140.

Chalasani N, Abdelmalek MF, Garcia-Tsao G, Vuppalanchi R, Alkhouri N, Rinella M, Noureddin M, Pyko M, Shiffman M, Sanyal A, Allgood A, Shlevin H, Horton R, Zomer E, Irish W, Goodman Z, Harrison SA, Traber PG. Effects of Belapectin, an Inhibitor of Galectin-3, in Patients With Nonalcoholic Steatohepatitis With Cirrhosis and Portal Hypertension. Gastroenterology. 2020;158(5):1334-1345.e1335.

Chamberlain JM, Kapur J, Shinnar S, Elm J, Holsti M, Babcock L, Rogers A, Barsan W, Cloyd J, Lowenstein D, Bleck TP, Conwit R, Meinzer C, Cock H, Fountain NB, Underwood E, Connor JT, Silbergleit R. Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial. Lancet. 2020;395(10231):1217-1224.

Chiang CH, Won SM, Orsborn AL, Yu KJ, Trumpis M, Bent B, Wang C, Xue Y, Min S, Woods V, Yu C, Kim BH, Kim SB, Huq R, Li J, Seo KJ, Vitale F, Richardson A, Fang H, Huang Y, Shepard K, Pesaran B, Rogers JA, Viventi J. Development of a neural interface for high-definition, long-term recording in rodents and nonhuman primates. Science Translational Medicine. 2020;12(538).

Daniels J, Doukas PG, Escala MEM, Ringbloom KG, Shih DJH, Yang J, Tegtmeyer K, Park J, Thomas JJ, Selli ME, Altunbulakli C, Gowthaman R, Mo SH, Jothishankar B, Pease DR, Pro B, Abdulla FR, Shea C, Sahni N, Gru AA, Pierce BG, Louissaint A, Jr., Guitart J, Choi J. Cellular origins and genetic landscape of cutaneous gamma delta T cell lymphomas. Nature Communications. 2020;11(1):1806.

Ghinai I, McPherson TD, Hunter JC, Kirking HL, Christiansen D, Joshi K, Rubin R, Morales-Estrada S, Black SR, Pacilli M, Fricchione MJ, Chugh RK, Walblay KA, Ahmed NS, Stoecker WC, Hasan NF, Burdsall DP, Reese HE, Wallace M, Wang C, Moeller D, Korpics J, Novosad SA, Benowitz I, Jacobs MW, Dasari VS, Patel MT, Kauerauf J, Charles EM, Ezike NO, Chu V, Midgley CM, Rolfes MA, Gerber SI, Lu X, Lindstrom S, Verani JR, Layden JE. First known person-to-person transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the USA. Lancet. 2020;395(10230):1137-1144.

Gratton C, Smith DM, Dorn M. Digging Deeper to Chart the Landscape of Human Brain Development. Neuron. 2020;106(2):209-211.

Jampol LM, Glassman AR, Sun J. Evaluation and Care of Patients with Diabetic Retinopathy. New England Journal of Medicine. 2020;382(17):1629-1637.

Kafader JO, Melani RD, Durbin KR, Ikwuagwu B, Early BP, Fellers RT, Beu SC, Zabrouskov V, Makarov AA, Maze JT, Shinholt DL, Yip PF, Tullman-Ercek D, Senko MW, Compton PD, Kelleher NL. Multiplexed mass spectrometry of individual ions improves measurement of proteoforms and their complexes. Nature Methods. 2020;17(4):391-394.

Kazi DS, Bellows BK, Baron SJ, Shen C, Cohen DJ, Spertus JA, Yeh RW, Arnold SV, Sperry BW, Maurer MS, Shah SJ.Cost-Effectiveness of Tafamidis Therapy for Transthyretin Amyloid Cardiomyopathy. Circulation. 2020;141(15):1214-1224.

Kloetgen A, Thandapani P, Ntziachristos P, Ghebrechristos Y, Nomikou S, Lazaris C, Chen X, Hu H, Bakogianni S, Wang J, Fu Y, Boccalatte F, Zhong H, Paietta E, Trimarchi T, Zhu Y, Van Vlierberghe P, Inghirami GG, Lionnet T, Aifantis I, Tsirigos A. Three-dimensional chromatin landscapes in T cell acute lymphoblastic leukemia. Nature Genetics. 2020;52(4):388-400.

Lahiri AK, Bevan MD.Dopaminergic Transmission Rapidly and Persistently Enhances Excitability of D1 Receptor-Expressing Striatal Projection Neurons. Neuron. 2020;106(2):277-290.e276.

Lindestam Arlehamn CS, Dhanwani R, Pham J, Kuan R, Frazier A, Rezende Dutra J, Phillips E, Mallal S, Roederer M, Marder KS, Amara AW, Standaert DG, Goldman JG, Litvan I, Peters B, Sulzer D, Sette A. alpha-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson's disease. Nat Communications. 2020;11(1):1875.

Ma C, Clark S, Liu Z, Liang L, Firdaus Y, Tao R, Han A, Liu X, Li LJ, Anthopoulos TD, Hersam MC, Wu T. Solution-Processed Mixed-Dimensional Hybrid Perovskite/Carbon Nanotube Electronics. ACS Nano. 2020;14(4):3969-3979.

Ortega JA, Daley EL, Kour S, Samani M, Tellez L, Smith HS, Hall EA, Esengul YT, Tsai YH, Gendron TF, Donnelly CJ, Siddique T, Savas JN, Pandey UB, Kiskinis E. Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity. Neuron. 2020;106(1):90-107.e113.

Owens DK, Davidson KW, Krist AH, Barry MJ, Cabana M, Caughey AB, Curry SJ, Donahue K, Doubeni CA, Epling JW, Jr., Kubik M, Ogedegbe G, Pbert L, Silverstein M, Simon MA, Tseng CW, Wong JB. Primary Care Interventions for Prevention and Cessation of Tobacco Use in Children and Adolescents: US Preventive Services Task Force Recommendation Statement. JAMA. 2020;323(16):1590-1598.

Owens DK, Davidson KW, Krist AH, Barry MJ, Cabana M, Caughey AB, Donahue K, Doubeni CA, Epling JW, Jr., Kubik M, Ogedegbe G, Pbert L, Silverstein M, Simon MA, Tseng CW, Wong JB. Screening for Bacterial Vaginosis in Pregnant Persons to Prevent Preterm Delivery: US Preventive Services Task Force Recommendation Statement. JAMA. 2020;323(13):1286-1292.

Rosencrance CD, Ammouri HN, Yu Q, Ge T, Rendleman EJ, Marshall SA, Eagen KP. Chromatin Hyperacetylation Impacts Chromosome Folding by Forming a Nuclear Subcompartment. Molecular Cell. 2020;78(1):112-126.e112.

Ryall S, Zapotocky M, Fukuoka K, Nobre L, Guerreiro Stucklin A, Bennett J, Siddaway R, Li C, Pajovic S, Arnoldo A, Kowalski PE, Johnson M, Sheth J, Lassaletta A, Tatevossian RG, Orisme W, Qaddoumi I, Surrey LF, Li MM, Waanders AJ, Gilheeney S, Rosenblum M, Bale T, Tsang DS, Laperriere N, Kulkarni A, Ibrahim GM, Drake J, Dirks P, Taylor MD, Rutka JT, Laughlin S, Shroff M, Shago M, Hazrati LN, D'Arcy C, Ramaswamy V, Bartels U, Huang A, Bouffet E, Karajannis MA, Santi M, Ellison DW, Tabori U, Hawkins C. Integrated Molecular and Clinical Analysis of 1,000 Pediatric Low-Grade Gliomas. Cancer Cell. 2020;37(4):569-583.e565.

Schultz KR, Kariminia A, Ng B, Abdossamadi S, Lauener M, Nemecek ER, Wahlstrom JT, Kitko CL, Lewis VA, Schechter T, Jacobsohn DA, Harris AC, Pulsipher MA, Bittencourt H, Choi SW, Caywood EH, Kasow KA, Bhatia M, Oshrine BR, Flower A, Chaudhury S, Coulter D, Chewning JH, Joyce M, Savasan S, Pawlowska AB, Megason GC, Mitchell D, Cheerva AC, Lawitschka A, Azadpour S, Ostroumov E, Subrt P, Halevy A, Mostafavi S, Cuvelier GDE. Immune profile differences between chronic GVHD and late acute GVHD: results of the ABLE/PBMTC 1202 studies. Blood. 2020;135(15):1287-1298.

Shah KP, deRegnier RO, Grobman WA, Bennett AC. Neonatal Mortality After Interhospital Transfer of Pregnant Women for Imminent Very Preterm Birth in Illinois. JAMA Pediatrics. 2020.

Stone NJ, Blumenthal RS, Lloyd-Jones D, Grundy SM. Comparing Primary Prevention Recommendations: A Focused Look at United States and European Guidelines on Dyslipidemia. Circulation. 2020;141(14):1117-1120.

Virani SS, Smith SC, Jr., Stone NJ, Grundy SM. Secondary Prevention for Atherosclerotic Cardiovascular Disease: Comparing Recent US and European Guidelines on Dyslipidemia. Circulation. 2020;141(14):1121-1123.

Won SM, Song E, Reeder JT, Rogers JA. Emerging Modalities and Implantable Technologies for Neuromodulation. Cell. 2020;181(1):115-135.

 Zhong VW, Van Horn L, Greenland P, Carnethon MR, Ning H, Wilkins JT, Lloyd-Jones DM, Allen NB. Associations of Processed Meat, Unprocessed Red Meat, Poultry, or Fish Intake With Incident Cardiovascular Disease and All-Cause Mortality. JAMA Internal Medicine. 2020.

Abdella R, Aggarwal M, Okura T, Lamb RA, He Y. Structure of a paramyxovirus polymerase complex reveals a unique methyltransferase-CTD conformation. Proceedings of the National Academy of Sciences of the United States of America. 2020;117(9):4931-4941.

Agarwal A, Dayal A, Kircher SM, Chen RC, Royce TJ. Analysis of Price Transparency via National Cancer Institute-Designated Cancer Centers' Chargemasters for Prostate Cancer Radiation Therapy. Jama Oncology. 2020;6(3):409-412.

Allen JP, Ozer EA, Minasov G, Shuvalova L, Kiryukhina O, Satchell KJF, Hauser AR. A comparative genomics approach identifies contact-dependent growth inhibition as a virulence determinant. Proceedings of the National Academy of Sciences of the United States of America. 2020;117(12):6811-6821.

Backer CL, Pasquali SK, Dearani JA. Improving National Outcomes in Congenital Heart Surgery: The Time Has Come for Regionalization of Care. Circulation. 2020;141(12):943-945.

Bai B, Wang XS, Li YX, Chen PC, Yu KW, Dey KK, Yarbro JM, Han X, Lutz BM, Rao SQ, Jiao Y, Sifford JM, Han J, Wang MH, Tan HY, Shaw TI, Cho JH, Zhou SP, Wang H, Niu MM, Mancieri A, Messler KA, Sun XJ, Wu ZP, Pagala V, High AA, Bi WJ, Zhang H, Chi HB, Haroutunian V, Zhang B, Beach TG, Yu G, Peng JM. Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer's Disease Progression. Neuron. 2020;105(6):975.

Beck ME, Shylendra A, Sangwan VK, Guo S, Gaviria Rojas WA, Yoo H, Bergeron H, Su K, Trivedi AR, Hersam MC. Spiking neurons from tunable Gaussian heterojunction transistors. Nat Communications. 2020;11(1):1565.

Brazee PL, Morales-Nebreda L, Magnani ND, Garcia JG, Misharin AV, Ridge KM, Budinger GRS, Iwai K, Dada LA, Sznajder JI. Linear ubiquitin assembly complex regulates lung epithelial-driven responses during influenza infection. Journal of Clinical Investigation. 2020;130(3):1301-1314.

Chung HU, Rwei AY, Hourlier-Fargette A, Xu S, Lee KY, Dunne EC, Xie ZQ, Liu CR, Carlini A, Kim DH, Ryu D, Kulikova E, Cao JY, Odland IC, Fields KB, Hopkins B, Banks A, Ogle C, Grande D, Park JB, Kim J, Irie M, Jang H, Lee JH, Park Y, Kim J, Jo HH, Hahm H, Avila R, Xu YH, Namkoong M, Kwak JW, Suen E, Paulus MA, Kim RJ, Parsons BV, Human KA, Kim SS, Patel M, Reuther W, Kim HS, Lee SH, Leedle JD, Yun YJ, Rigali S, Son T, Jung IW, Arafa H, Soundararajan VR, Ollech A, Shukla A, Bradley A, Schau M, Rand CM, Marsillio LE, Harris ZL, Huang YG, Hamvas A, Paller AS, Weese-Mayer DE, Lee JY, Rogers JA. Skin-interfaced biosensors for advanced wireless physiological monitoring in neonatal and pediatric intensive-care units. Nature Medicine. 2020;26(3):418.

Du XF, Carvalho-de-Souza JL, Wei CF, Carrasquel-Ursulaez W, Lorenzo Y, Gonzalez N, Kubota T, Staisch J, Hain T, Petrossian N, Xu M, Latorre R, Bezanilla F, Gomez CM. Loss-of-function BK channel mutation causes impaired mitochondria and progressive cerebellar ataxia. Proceedings of the National Academy of Sciences of the United States of America. 2020;117(11):6023-6034.

Han Y, Zhang Y, Kim H, Grayson VS, Jovasevic V, Ren W, Centeno MV, Guedea AL, Meyer MAA, Wu Y, Gutruf P, Surmeier DJ, Gao C, Martina M, Apkarian AV, Rogers JA, Radulovic J. Excitatory VTA to DH projections provide a valence signal to memory circuits. Nat Communications. 2020;11(1):1466.

Hirano I, Furuta GT. Approaches and Challenges to Management of Pediatric and Adult Patients With Eosinophilic Esophagitis. Gastroenterology. 2020;158(4):840-851.

Lewis AA, Ayers CR, Selvin E, Neeland I, Ballantyne CM, Nambi V, Pandey A, Powell-Wiley TM, Drazner MH, Carnethon MR, Berry JD, Seliger SL, DeFilippi CR, de Lemos JA. Racial Differences in Malignant Left Ventricular Hypertrophy and Incidence of Heart Failure: A Multicohort Study. Circulation. 2020;141(12):957-967.

Li S, Zhong C, Henning A, Sangwan VK, Zhou Q, Liu X, Rahn MS, Wells SA, Park HY, Luxa J, Sofer Z, Facchetti A, Darancet P, Marks TJ, Lauhon LJ, Weiss EA, Hersam MC. Molecular-Scale Characterization of Photoinduced Charge Separation in Mixed-Dimensional InSe-Organic van der Waals Heterostructures. ACS Nano. 2020;14(3):3509-3518.

Mahinrad S, Kurian S, Garner CR, Sedaghat S, Nemeth AJ, Moscufo N, Higgins JP, Jacobs DR, Jr., Hausdorff JM, Lloyd-Jones DM, Sorond FA. Cumulative Blood Pressure Exposure During Young Adulthood and Mobility and Cognitive Function in Midlife. Circulation. 2020;141(9):712-724.

Mulkey SB, Arroyave-Wessel M, Peyton C, Bulas DI, Fourzali Y, Jiang JJ, Russo S, McCarter R, Msall ME, du Plessis AJ, DeBiasi RL, Cure C. Neurodevelopmental Abnormalities in Children With In Utero Zika Virus Exposure Without Congenital Zika Syndrome. JAMA Pediatrics. 2020;174(3):269-276.

Nabbout R, Mistry A, Zuberi S, Villeneuve N, Gil-Nagel A, Sanchez-Carpintero R, Stephani U, Laux L, Wirrell E, Knupp K, Chiron C, Farfel G, Galer BS, Morrison G, Lock M, Agarwal A, Auvin S, Grp DSS. Fenfluramine for Treatment-Resistant Seizures in Patients With Dravet Syndrome Receiving Stiripentol-Inclusive Regimens A Randomized Clinical Trial. JAMA Neurology. 2020;77(3):300-308.

Niederman MS, Alder J, Bassetti M, Boateng F, Cao B, Corkery K, Dhand R, Kaye KS, Lawatscheck R, McLeroth P, Nicolau DP, Wang C, Wood GC, Wunderink RG, Chastre J. Inhaled amikacin adjunctive to intravenous standard-of-care antibiotics in mechanically ventilated patients with Gram-negative pneumonia (INHALE): a double-blind, randomised, placebo-controlled, phase 3, superiority trial. Lancet Infectious Diseases. 2020;20(3):330-340.

Ragusa S, Prat-Luri B, Gonzalez-Loyola A, Nassiri S, Squadrito ML, Guichard A, Cavin S, Gjorevski N, Barras D, Marra G, Lutolf MP, Perentes J, Corse E, Bianchi R, Wetterwald L, Kim J, Oliver G, Delorenzi M, De Palma M, Petrova TV. Antiangiogenic immunotherapy suppresses desmoplastic and chemoresistant intestinal tumors in mice. Journal of Clinical Investigation. 2020;130(3):1199-1216.

Shah SJ, Borlaug BA, Kitzman DW, McCulloch AD, Blaxall BC, Agarwal R, Chirinos JA, Collins S, Deo RC, Gladwin MT, Granzier H, Hummel SL, Kass DA, Redfield MM, Sam F, Wang TJ, Desvigne-Nickens P, Adhikari BB. Research Priorities for Heart Failure With Preserved Ejection Fraction: National Heart, Lung, and Blood Institute Working Group Summary. Circulation. 2020;141(12):1001-1026.

Sparano JA, Gray RJ, Makower D, Albain KS, Saphner TJ, Badve SS, Wagner LI,Kaklamani VG, Keane MM, Gomez HL, Reddy PS, Goggins TF, Mayer IA, Toppmeyer DL, Brufsky AM, Goetz MP, Berenberg JL, Mahalcioiu C, Desbiens C, Hayes DF, Dees EC, Geyer CE, Olson JA, Wood WC, Lively T, Paik S, Ellis MJ, Abrams J, Sledge GW. Clinical Outcomes in Early Breast Cancer With a High 21-Gene Recurrence Score of 26 to 100 Assigned to Adjuvant Chemotherapy Plus Endocrine Therapy A Secondary Analysis of the TAILORx Randomized Clinical Trial. JAMA Oncology. 2020;6(3):367-374.

Thiam HR, Wong SL, Qiu R, Kittisopikul M, Vahabikashi A, Goldman AE, Goldman RD, Wagner DD, Waterman CM. NETosis proceeds by cytoskeleton and endomembrane disassembly and PAD4-mediated chromatin decondensation and nuclear envelope rupture. Proceedings of the National Academy of Sciences of the United States of America. 2020;117(13):7326-7337.

Thijssen EH, La Joie R, Wolf A, Strom A, Wang P, Iaccarino L, Bourakova V, Cobigo Y, Heuer H, Spina S, VandeVrede L, Chai XY, Proctor NK, Airey DC, Shcherbinin S, Evans CD, Sims JR, Zetterberg H, Blennow K, Karydas AM, Teunissen CE, Kramer JH, Grinberg LT, Seeley WW, Rosen H, Boeve BF, Miller BL, Rabinovici GD, Dage JL, Rojas JC, Boxer AL, Forsberg L, Knopman DS, Graff-Radford N, Grossman M, Huey EH, Onyike C, Kaufer D, Roberson E, Ghoshal N, Weintraub S, Appleby B, Litvan I, Kerwin D, Mendez M, Bordelon Y, Coppola G, Ramos EM, Tartaglia MC, Hsiung GY, MacKenzie I, Domoto-Reilly K, Foroud T, Dickerson BC, Adv Res Treatment Frontotemporal L, Advancing R. Diagnostic value of plasma phosphorylated tau181 in Alzheimer's disease and frontotemporal lobar degeneration. Nature Medicine. 2020;26(3):387.

Welikovitch LA, Do Carmo S, Magloczky Z, Malcolm JC, Loke J, Klein WL, Freund T, Cuello AC. Early intraneuronal amyloid triggers neuron-derived inflammatory signaling in APP transgenic rats and human brain. Proceedings of the National Academy of Sciences of the United States of America. 2020;117(12):6844-6854.

Burton A, Obaid SN, Vazquez-Guardado A, Schmit MB, Stuart T, Cai L, Chen ZY, Kandela I, Haney CR, Waters EA, Cai HJ, Rogers JA, Lu LY, Gutruf P. Wireless, battery-free subdermally implantable photometry systems for chronic recording of neural dynamics. Proceedings of the National Academy of Sciences of the United States of America. 2020;117(6):2835-2845.

Dey N, Kochman ML, Komanduri S, Melson JE, Muthusamy VR. Report from the AGA Center for GI Innovation and Technology's Consensus Conference: Envisioning Next-Generation Paradigms in Colorectal Cancer Screening and Surveillance. Gastroenterology. 2020;158(3):455-460.

Doebele RC, Drilon A, Paz-Ares L, Siena S, Shaw AT, Farago AF, Blakely CM, Seto T, Cho BC, Tosi D, Besse B, Chawla SP, Bazhenova L, Krauss JC, Chae YK, Barve M, Garrido-Laguna I, Liu SV, Conkling P, John T, Fakih M, Sigal D, Loong HH, Buchschacher GL, Garrido P, Nieva J, Steuer C, Overbeck TR, Bowles DW, Fox E, Riehl T, Chow-Maneval E, Simmons B, Cui N, Johnson A, Eng S, Wilson TR, Demetri GD, Trial I. Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1-2 trials. Lancet Oncology. 2020;21(2):271-282.

Drilon A, Siena S, Dziadziuszko R, Barlesi F, Krebs MG, Shaw AT, de Braud F, Rolfo C, Ahn MJ, Wolf J, Seto T, Cho BC, Patel MR, Chiu CH, John T, Goto K, Karapetis CS, Arkenau HT, Kim SW, Ohe Y, Li YC, Chae YK, Chung CH, Otterson GA, Murakami H, Lin CC, Tan DSW, Prenen H, Riehl T, Chow-Maneval E, Simmons B, Cui N, Johnson A, Eng S, Wilson TR, Doebele RC, Trial I. Entrectinib in ROS1 fusion-positive non-small-cell lung cancer: integrated analysis of three phase 1-2 trials. Lancet Oncology. 2020;21(2):261-270.

Ferrer JR, Sinegra AJ, Ivancic D, Yeap XY, Qiu L, Wang JJ, Zhang ZJ, Wertheim JA, Mirkin CA. Structure-Dependent Biodistribution of Liposomal Spherical Nucleic Acids. ACS Nano. 2020;14(2):1682-1693.

Gallego JA, Perich MG, Chowdhury RH, Solla SA, Miller LE. Long-term stability of cortical population dynamics underlying consistent behavior. Nature Neuroscience. 2020;23(2):260.

Greene DJ, Marek S, Gordon EM, Siegel JS, Gratton C, Laumann TO, Gilmore AW, Berg JJ, Nguyen AL, Dierker D, Van AN, Ortega M, Newbold DJ, Hampton JM, Nielsen AN, McDermott KB, Roland JL, Norris SA, Nelson SM, Snyder AZ, Schlaggar BL, Petersen SE, Dosenbach NUF. Integrative and Network-Specific Connectivity of the Basal Ganglia and Thalamus Defined in Individuals. Neuron. 2020;105(4):742.

Jin X, Chandramouli C, Allocco B, Gong E, Lam CSP, Yan LL. Women's Participation in Cardiovascular Clinical Trials From 2010 to 2017. Circulation. 2020;141(7):540-548.

Kosciuk T, Price IR, Zhang X, Zhu C, Johnson KN, Zhang S, Halaby SL, Komaniecki GP, Yang M, DeHart CJ, Thomas PM, Kelleher NL, Fromme JC, Lin H. NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle. Nature Communications. 2020;11(1):1067.

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