Northwestern University Feinberg School of Medicine
Research

High-Impact-Factor Research 2019

Adelman JS, Applebaum JR, Schechter CB, Berger MA, Reissman SH, Thota R, Racine AD, Vawdrey DK, Green RA, Salmasian H, Schiff GD, Wright A, Landman A, Bates DW, Koppel R, Galanter WL, Lambert BL, Paparella S, Southern WN. Effect of Restriction of the Number of Concurrently Open Records in an Electronic Health Record on Wrong-Patient Order Errors A Randomized Clinical Trial. JAMA-Journal of the American Medical Association. 2019;321(18):1780-1787.

Baker CW, Glassman AR, Beaulieu WT, et al. (including Jampol LM). Effect of Initial Management With Aflibercept vs Laser Photocoagulation vs Observation on Vision Loss Among Patients With Diabetic Macular Edema Involving the Center of the Macula and Good Visual Acuity A Randomized Clinical Trial. JAMA-Journal of the American Medical Association. 2019;321(19):1880-1894.

Beura LK, Fares-Frederickson NJ, Steinert EM, Scott MC, Thompson EA, Fraser KA, Schenke JM, Vezys V, Masopust D. CD4(+) resident memory T cells dominate immunosurveillance and orchestrate local recall responses. Journal of Experimental Medicine. 2019;216(5):1214-1229.

Cedernaes J, Huang WY, Ramsey KM, Waldeck N, Cheng L, Marcheva B, Omura C, Kobayashi Y, Peek CB, Levine DC, Dhir R, Awatramani R, Bradfield CA, Wang XZA, Takahashi JS, Mokadem M, Ahima RS, Bass J. Transcriptional Basis for Rhythmic Control of Hunger and Metabolism within the AgRP Neuron. Cell Metabolism. 2019;29(5):1078.

Chang SM, Messersmith H, Ahluwalia M, Andrews D, Brastianos PK, Gaspar LE, Gatson NTN, Jordan JT, Khasraw M, Lassman AB, Maues J, Mrugala M, Raizer J, Schiff D, Stevens G, Sumrall A, van den Bent M, Vogelbaum MA. Anticonvulsant Prophylaxis and Steroid Use in Adults With Metastatic Brain Tumors: ASCO and SNO Endorsement of the Congress of Neurological Surgeons Guidelines. Journal of Clinical Oncology. 2019;37(13):1130.

Diener HC, Sacco RL, Easton JD, Granger CB, Bernstein RA, Uchiyama S, Kreuzer J, Cronin L, Cotton D, Grauer C, Brueckmann M, Chernyatina M, Donnan G, Ferro JM, Grond M, Kallmunzer B, Krupinski J, Lee BC, Lemmens R, Masjuan J, Odinak M, Saver JL, Schellinger PD, Toni D, Toyoda K. Dabigatran for Prevention of Stroke after Embolic Stroke of Undetermined Source. New England Journal of Medicine. 2019;380(20):1906-1917.

Feigin VL, Nichols E, Alam T, et al. (including Yano Y). Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurology. 2019;18(5):459-480.

Gyamfi-Bannerman C, Zupancic JAF, Sandoval G, Grobman WA, et al. Cost-effectiveness of Antenatal Corticosteroid Therapy vs No Therapy in Women at Risk of Late Preterm Delivery A Secondary Analysis of a Randomized Clinical Trial. JAMA Pediatrics. 2019;173(5):462-468.

Ji Z, He LZ, Regev A, Struhl K. Inflammatory regulatory network mediated by the joint action of NF-kB, STAT3, and AP-1 factors is involved in many human cancers. Proceedings of the National Academy of Sciences of the United States of America. 2019;116(19):9453-9462.

Lazarus SC, Krishnan JA, King TS, et al. (including Smith L) Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level. New England Journal of Medicine. 2019;380(21):2009-2019.

Mack MJ, Leon MB, Thourani VH, Makkar R, Kodali SK, Russo M, Kapadia SR, Malaisrie SC, Cohen DJ, Pibarot P, Leipsic J, Hahn RT, Blanke P, Williams MR, McCabe JM, Brown DL, Babaliaros V, Goldman S, Szeto WY, Genereux P, Pershad A, Pocock SJ, Alu MC, Webb JG, Smith CR, Investigators P. Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients.New England Journal of Medicine. 2019;380(18):1695-1705.

Martinez-Velez N, Garcia-Moure M, Marigil M, Gonzalez-Huarriz M, Puigdelloses M, Perez-Larraya JG, Zalacain M, Marrodan L, Varela-Guruceaga M, Laspidea V, Aristu JJ, Ramos LI, Tejada-Solis S, Diez-Valle R, Jones C, Mackay A, Martinez-Climent JA, Garcia-Barchino MJ, Raabe E, Monje M, Becher OJ, Junier MP, El-Habr EA, Chneiweiss H, Aldave G, Jiang H, Fueyo J, Patino-Garcia A, Gomez-Manzano C, Alonso MM. The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models. Nature Communications. 2019;10:10.

Moore KN, Secord AA, Geller MA, Miller DS, Cloven N, Fleming GF, Hendrickson AEW, Azodi M, DiSilvestro P, Oza AM, Cristea M, Berek JS, Chan JK, Rimel BJ, Matei DE, Li Y, Sun KM, Luptakova K, Matulonis UA, Monk BJ. Niraparib monotherapy for late-line treatment of ovarian cancer (QUADRA): a multicentre, open-label, single-arm, phase 2 trial. Lancet Oncology. 2019;20(5):636-648.

Perak AM, Ning HY, Kit BK, de Ferranti SD, Van Horn LV, Wilkins JT, Lloyd-Jones DM. Trends in Levels of Lipids and Apolipoprotein B in US Youths Aged 6 to 19 Years, 1999-2016. JAMA-Journal of the American Medical Association. 2019;321(19):1895-1905.

Reynolds AW, Mata-Miguez J, Miro-Herrans A, Briggs-Cloud M, Sylestine A, Barajas-Olmos F, Garcia-Ortiz H, Rzhetskaya M, Orozco L, Raff JA, Hayes MG, Bolnick DA. Comparing signals of natural selection between three Indigenous North American populations. Proceedings of the National Academy of Sciences of the United States of America. 2019;116(19):9312-9317.

Wang SY, Qin L, Yamankurt G, Skakuj K, Huang ZY, Chen PC, Dominguez D, Lee A, Zhang B, Mirkin CA. Rational vaccinology with spherical nucleic acids. Proceedings of the National Academy of Sciences of the United States of America. 2019;116(21):10473-10481.

Warrington NM, Beaumont RN, Horikoshi M, et al. (including Nodzenski M, Scholtens DM, Lowe WL, Hayes MG). Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. Nature Genetics. 2019;51(5):804.

Watanabe S, Alexander M, Misharin AV, Budinger GRS. The role of macrophages in the resolution of inflammation. Journal Clinical Investigation. 2019;130.

Zhao JW, Lee EE, Kim J, Yang R, Chamseddin B, Ni CY, Gusho E, Xie Y, Chiang CM, Buszczak M, Zhan XW, Laimins L, Wang RC. Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus. Nature Communications. 2019;10:12.

Amsterdam SH, Stanev TK, Zhou Q, Lou AJ, Bergeron H, Darancet P, Hersam MC, Stern NP, Marks TJ. Electronic Coupling in Metallophthalocyanine-Transition Metal Dichalcogenide Mixed-Dimensional Heterojunctions. ACS Nano. 2019 Apr 23;13(4):4183-4190.

Bentley AR, Sung YJ, Brown MR, et al. (including Liu K).  Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Nature Genetics. 2019 Apr;51(4):636.

Carota IA, Kenig-Kozloysky Y, Onay T, Scott R, Thomson BR, Souma T, Bartlett CS, Li YY, Procissi D, Ramirez V, Yamaguchi S, Tarjus A, Tanna CE, Li CJ, Eremina V, Vestweber D, Nadipupo SS, Breyer MD, Quaggin SE. Targeting VE-PTP phosphatase protects the kidney from diabetic injury. Journal of Experimental Medicine. 2019 Apr;216(4):936-949.

Curry SJ, Krist AH, Owens DK, Barry MJ, Cabana M, Caughey AB, Doubeni CA, Epling JW, Kemper AR, Kubik M, Landefeld CS, Mangione CM, Pbert L, Silverstein M, Simon MA, Tseng CW, Wong JB, Force USPST. Screening for Elevated Blood Lead Levels in Children and Pregnant Women US Preventive Services Task Force Recommendation Statement. JAMA-Journal of the American Medical Association. 2019 Apr;321(15):1502-1509.

Franzmeier N, Rubinski A, Neitzel J, et al. (including Mesulam MM, Mesulam MM, Rogalski E, Lipowski K, Weintraub S). The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory. Nature Communications. 2019 Apr;10:12.

Garrett-Bakelman FE, Darshi M, Green SJ, et al. (including Turek FW). The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight. Science. 2019 Apr;364(6436):144.

Gladstein S, Almassalha LM, Cherkezyan L, Chandler JE, Eshein A, Eid A, Zhang D, Wu WL, Bauer GM, Stephens AD, Morochnik S, Subramanian H, Marko JF, Ameer GA, Szleifer I, Backman V. Multimodal interference-based imaging of nanoscale structure and macromolecular motion uncovers UV induced cellular paroxysm. Nature Communications. 2019 Apr;10:15.

Kiraly B, Liu X, Wang L, Zhang Z, Mannix AJ, Fisher BL, Yakobson BI, Hersam MC, Guisinger NP. Borophene Synthesis on Au(111). ACS Nano. 2019 Apr 23;13(4):3816-3822.

Kuppermann N, Dayan PS, Levine DA, Vitale M, Tzimenatos L, Tunik MG, Saunders M, Ruddy RM, Roosevelt G, Rogers AJ, Powell EC, Nigrovic LE, Muenzer J, Linakis JG, Grisanti K, Jaffe DM, Hoyle JD, Greenberg R, Gattu R, Cruz AT, Crain EF, Cohen DM, Brayer A, Borgialli D, Bonsu B, Browne L, Blumberg S, Bennett JE, Atabaki SM, Anders J, Alpern ER, Miller B, Casper TC, Dean JM, Ramilo O, Mahajan P, Pecarn. A Clinical Prediction Rule to Identify Febrile Infants 60 Days and Younger at Low Risk for Serious Bacterial Infections. JAMA Pediatrics. 2019 Apr;173(4):342-351.

Liu XL, Wang LQ, Li SW, Rahn MS, Yakobson BI, Hersam MC. Geometric imaging of borophene polymorphs with functionalized probes. Nature Communications. 2019 Apr;10:7.

Ng K, Nimeiri HS, McCleary NJ, Abrams TA, Yurgelun MB, Cleary JM, Rubinson DA, Schrag D, Miksad R, Bullock AJ, Allen J, Zuckerman D, Chan E, Chan JA, Wolpin BM, Constantine M, Weckstein DJ, Faggen MA, Thomas CA, Kournioti C, Yuan C, Ganser C, Wilkinson B, Mackintosh C, Zheng H, Hollis BW, Meyerhardt JA, Fuchs CS. Effect of High-Dose vs Standard-Dose Vitamin D-3 Supplementation on Progression-Free Survival Among Patients With Advanced or Metastatic Colorectal Cancer The SUNSHINE Randomized Clinical Trial. JAMA-Journal of the American Medical Association. 2019 Apr;321(14):1370-1379.

Rodriguez AE, Ducker GS, Billingham LK, Martinez CA, Mainolfi N, Suri V, Friedman A, Manfredi MG, Weinberg SE, Rabinowitz JD, Chandel NS. Serine Metabolism Supports Macrophage IL-1 beta Production. Cell Metabolism. 2019 Apr;29(4):1003.

Tombal B, Saad F, Penson D, Hussain M, Sternberg CN, Morlock R, Ramaswatny K, Ivanescu C, Attard G. Patient-reported outcomes following enzalutamide or placebo in men with non-metastatic, castration-resistant prostate cancer (PROSPER): a multicentre, randomised, double-blind, phase 3 trial.Lancet Oncology. 2019 Apr;20(4):556-569.

Waikar SS, Srivastava A, Palsson R, Shafi T, Hsu CY, Sharma K, Lash JP, Chen J, He J, Lieske J, Xie DW, Zhang XM, Feldman HI, Curhan GC, Appel LJ, Go AS, Kusek JW, Rao P, Rahman M, Townsend RR, Chronic Renal Insufficiency C. Association of Urinary Oxalate Excretion With the Risk of Chronic Kidney Disease Progression. JAMA Internal Medicine. 2019 Apr;179(4):542-551.

Yamawaki N, Li XJ, Lambot L, Ren LY, Radulovic J, Shepherd GMG. Long-range inhibitory intersection of a retrosplenial thalamocortical circuit by apical tuft-targeting CA1 neurons. Nature Neuroscience. 2019 Apr;22(4):618.

Zhao W, Wang X, Deik AA, Hanna DB, Wang T, Haberlen SA, Shah SJ, Lazar JM, Hodis HN, Landay AL, Yu B, Gustafson D, Anastos K, Post WS, Clish CB, Kaplan RC, Qi Q. Elevated Plasma Ceramides Are Associated With Antiretroviral Therapy Use and Progression of Carotid Artery Atherosclerosis in HIV Infection. Circulation. 2019 Apr 23;139(17):2003-2011.

 

Banerjee S, Gusho E, Gaughan C, Dong BH, Gu XR, Holvey-Bates E, Talukdar M, Li YZ, Weiss SR, Sicheri F, Saunthararajah Y, Stark GR, Silverman RH. OAS-RNase L innate immune pathway mediates the cytotoxicity of a DNA-demethylating drug. Proceedings of the National Academy of Sciences of the United States of America. 2019 Mar;116(11):5071-5076.

Chang BJ, Kittisopikul M, Dean KM, Roudot P, Welf ES, Fiolka R. Universal light-sheet generation with field synthesis. Nature Methods. 2019 Mar;16(3):235-238.

Chen PC, Liu MH, Du JSS, Meckes B, Wang SZ, Lin HX, Dravid VP, Wolverton C, Mirkin CA. Interface and heterostructure design in polyelemental nanoparticles. Science. 2019 Mar;363(6430):959.

Chung HU, Kim BH, Lee JY, Lee J, Xie ZQ, Ibler EM, Lee K, Banks A, Jeong JY, Kim J, Ogle C, Grande D, Yu Y, Jang H, Assem P, Ryu D, Kwak JW, Namkoong M, Park JB, Lee Y, Kim DH, Ryu A, Jeong J, You K, Ji BW, Liu ZJ, Huo QZ, Feng X, Deng YJ, Xu YS, Jang KI, Kim J, Zhang YH, Ghaffari R, Rand CM, Schau M, Hamvas A, Weese-Mayer DE, Huang YG, Lee SM, Lee CH, Shanbhag NR, Paller AS, Xu S, Rogers JA.Binodal, wireless epidermal electronic systems with in-sensor analytics for neonatal intensive care. Science. 2019 Mar;363(6430):947.

Crowley JJ, Szatkiewicz J, Kahler AK, Giusti-Rodriguez P, Ancalade N, Booker JK, Carr JL, Crawford GE, Losh M, Stockmeier CA, Taylor AK, Piven J, Sullivan PF. Common-variant associations with fragile X syndrome. Molecular Psychiatry. 2019 Mar;24(3):338-344.

Hoeman CM, Cordero FJ, Hu G, Misuraca K, Romero MM, Cardona HJ, Nazarian J, Hashizume R, McLendon R, Yu P, Procissi D, Gadd S, Becher OJ. ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis. Nature Communications. 2019 Mar;10:15.

Hoxhaj G, Ben-Sahra I, Lockwood SE, Timson RC, Byles V, Henning GT, Gao P, Selfors LM, Asara JM, Manning BD. Direct stimulation of NADP(+) synthesis through Akt-mediated phosphorylation of NAD kinase. Science. 2019 Mar;363(6431):1088.

Hu YM, Li M, Lu QS, et.al. (including Weintraub S.)A statistical framework for cross-tissue transcriptome-wide association analysis. Nature Genetics. 2019 Mar;51(3):568.

Krenzlin H, Behera P, Lorenz V, Passaro C, Zdioruk M, Nowicki MO, Grauwet K, Zhang H, Skubal M, Ito H, Zane R, Gutknecht M, Griessl MB, Ricklefs F, Ding L, Peled S, Rooj A, James CD, Cobbs CS, Cook CH, Chiocca EA, Lawler SE. Cytomegalovirus promotes murine glioblastoma growth via pericyte recruitment and angiogenesis. Journal of Clinical Investigation. 2019 Mar 11;130:1671-1683.

Kunkle BW, Grenier-Boley B, Sims R, et al. (including Bigio EH, Mesulam M, Weintraub S). Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Abeta, tau, immunity and lipid processing. Nature Genetics. 2019 Mar;51(3):414-430.

LeBleu VS, Kalluri R. Exosomes Exercise Inhibition of Anti-Tumor Immunity during Chemotherapy. Immunity. 2019 Mar;50(3):547-549.

Levine CS, Markus HR, Austin MK, Chen E, Miller GE. Students of color show health advantages when they attend schools that emphasize the value of diversity. Proceedings of the National Academy of Sciences of the United States of America. 2019 Mar;116(13):6013-6018.

Levine DM, Landon BE, Linder JA. Quality and Experience of Outpatient Care in the United States for Adults With or Without Primary Care. JAMA Internal Medicine. 2019 Mar;179(3):363-372.

McSharry SS, Beitel GJ. The Caspase-3 homolog DrICE regulates endocytic trafficking during Drosophila tracheal morphogenesis. Nature Communications. 2019 Mar;10:10.

O'Donnell M, Mente A, Rangarajan S, McQueen MJ, O'Leary N, Yin L, Liu XY, Swaminathan S, Khatib R, Rosengren A, Ferguson J, Smyth A, Lopez-Jaramillo P, Diaz R, Avezum A, Lanas F, Ismail N, Yusoff K, Dans A, Iqbal R, Szuba A, Mohammadifard N, Oguz A, Yusufali AH, Alhabib KF, Kruger IM, Yusuf R, Chifamba J, Yeates K, Dagenais G, Wielgosz A, Lear SA, Teo K, Yusuf S, Investigators P. Joint association of urinary sodium and potassium excretion with cardiovascular events and mortality: prospective cohort study. BMJ-British Medical Journal. 2019 Mar;364:14.

Piccini JP, Xu H, Cox M, Matsouaka RA, Fonarow GC, Butler J, Curtis AB, Desai N, Fang M, McCabe PJ, Page Ii RL, Turakhia M, Russo AM, Knight BP, Sidhu M, Hurwitz JL, Ellenbogen KA, Lewis WR. Adherence to Guideline-Directed Stroke Prevention Therapy for Atrial Fibrillation Is Achievable.Circulation. 2019 Mar 19;139(12):1497-1506.

Zhao J, Chen AX, Gartrell RD, Silverman AM, Aparicio L, Chu T, Bordbar D, Shan D, Samanamud J, Mahajan A, Filip I, Orenbuch R, Goetz M, Yamaguchi JT, Cloney M, Horbinski C, Lukas RV, Raizer J, Rae AI, Yuan JZ, Canoll P, Bruce JN, Saenger YM, Sims P, Iwamoto FM, Sonabend AM, Rabadan R. Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma. Nature Medicine. 2019 Mar;25(3):462.

Zhong VW, Van Horn L, Cornelis MC, Wilkins JT, Ning HY, Carnethon MR, Greenland P, Mentz RJ, Tucker KL, Zhao LH, Norwood AF, Lloyd-Jones DM, Allen NB. Associations of Dietary Cholesterol or Egg Consumption With Incident Cardiovascular Disease and Mortality. JAMA-Journal of the American Medical Association. 2019 Mar;321(11):1081-1095.

Zhou GY, Lane G, Notoe T, Arabkheradmand G, Gottfried JA, Schuele SU, Rosenow JM, Olofsson JK, Wilson DA, Zelano C. Human olfactory-auditory integration requires phase synchrony between sensory cortices. Nature Communications. 2019 Mar;10:12.

Butin-Israeli V, Bui TM, Wiesolek HL, Mascarenhas L, Lee JJ, Mehl LC, Knutson KR, Adam SA, Goldman RD, Beyder A, Wiesmuller L, Hanauer SB, Sumagin R.Neutrophil-induced genomic instability impedes resolution of inflammation and wound healing. Journal of Clinical Investigation. 2019 Feb 1;129(2):712-726.

Cella D, Grunwald V, Escudier B, Hammers HJ, George S, Nathan P, Grimm MO, Rini BI, Doan J, Ivanescu C, Paty J, Mekan S, Motzer RJ. Patient-reported outcomes of patients with advanced renal cell carcinoma treated with nivolumab plus ipilimumab versus sunitinib (CheckMate 214): a randomised, phase 3 trial. Lancet Oncology. 2019 Feb;20(2):297-310.

Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Davidson K, Doubeni CA, Epling JW, Grossman DC, Kemper AR, Kubik M, Landefeld CS, Mangione CM, Silverstein M, Simon MA, Tseng CW, Wong JB, Force USPST. Interventions to Prevent Perinatal Depression US Preventive Services Task Force Recommendation Statement. JAMA. 2019 Feb;321(6):580-587.

Daya M, Rafaels N, Brunetti TM, et al. (including Grammer L). Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations. Nature Communications. 2019 Feb;10:13.

Elfassy T, Swift SL, Glymour MM, Calonico S, Jacobs DR, Mayeda ER, Kershaw KN, Kiefe C, Al Hazzouri AZ. Associations of Income Volatility With Incident Cardiovascular Disease and All-Cause Mortality in a US Cohort 1990 to 2015. Circulation. 2019 Feb;139(7):850-859.

Frey TM, Florin TA, Caruso M, Zhang NH, Zhang Y, Mittiga MR. Effect of Intranasal Ketamine vs Fentanyl on Pain Reduction for Extremity Injuries in Children The PRIME Randomized Clinical Trial. JAMA Pediatrics. 2019 Feb;173(2):140-146.

Gerson JN, Handorf E, Villa D, Gerrie AS, Chapani P, Li S, Medeiros LJ, Wang MI, Cohen JB, Calzada O, Churnetski MC, Hill BT, Sawalha Y, Hernandez-Ilizaliturri FJ, Kothari S, Vose JM, Bast MA, Fenske TS, Gari SNR, Maddocks KJ, Bond D, Bachanova V, Kolla B, Chavez J, Shah B, Lansigan F, Burns TF, Donovan AM, Wagner-Johnston N, Messmer M, Mehta A, Anderson JK, Reddy N, Kovach AE, Landsburg DJ, Glenn M, Inwards DJ, Karmali R, Kaplan JB, Caimi PF, Rajguru S, Evens A, Klein A, Umyarova E, Pulluri B, Amengual JE, Lue JK, Diefenbach C, Fisher RI, Barta SK. Survival Outcomes of Younger Patients With Mantle Cell Lymphoma Treated in the Rituximab Era. Journal of Clinical Oncology. 2019 Feb;37(6):471.

Laramy CR, Lopez-Rios H, O'Brien MN, Girard M, Stawicki RJ, Lee B, de la Cruz MO, Mirkin CA. Controlled Symmetry Breaking in Colloidal Crystal Engineering with DNA. ACS Nano. 2019 Feb;13(2):1412-1420.

Lazic D, Sagare AP, Nikolakopoulou AM, Griffin JH, Vassar R, Zlokovic BV. 3K3A-activated protein C blocks amyloidogenic BACE1 pathway and improves functional outcome in mice. Journal of Experimental Medicine. 2019 Feb 4;216(2):279-293.

Liu M, Jiang Y, Wedow R, (including Cornelis MC). Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use. Nature Genetics. 2019 Feb;51(2):237-244.

Li WJ, Gauthier JM, Higashikubo R, Hsiao HM, Tanaka S, Vuong L, Ritter JH, Tong AY, Wong BW, Hachem RR, Puri V, Bharat A, Krupnick AS, Hsieh CS, Baldwin WM, Kelly FL, Palmer SM, Gelman AE, Kreisel D. Bronchus-associated lymphoid tissue-resident Foxp3(+) T lymphocytes prevent antibody-mediated lung rejection. Journal of Clinical Investigation. 2019 Feb;129(2):556-568.

McCann ME, de Graaff JC, Dorris L, et al. (including Surantham S). Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy (GAS): an international, multicentre, randomised, controlled equivalence trial. Lancet. 2019 Feb;393(10172):664-677.

Nan KW, Wang HL, Ning X, Miller KA, Wei C, Liu YP, Li HB, Xue YG, Xie ZQ, Luan HW, Zhang YH, Huang YG, Rogers JA, Braun PV. Soft Three-Dimensional Microscale Vibratory Platforms for Characterization of Nano-Thin Polymer Films. ACS Nano. 2019 Jan;13(1):449-457.

Shuen AY, Lanni S, Panigrahi GB, Edwards M, Yu L, Campbell BB, Mandel A, Zhang C, Zhukova N, Alharbi M, Bernstein M, Bowers DC, Carroll S, Cole KA, Constantini S, Crooks B, Dvir R, Farah R, Hijiya N, George B, Laetsch TW, Larouche V, Lindhorst S, Luiten RC, Magimairajan V, Mason G, Mason W, Mordechai O, Mushtaq N, Nicholas G, Oren M, Palma L, Pedroza LA, Ramdas J, Samuel D, Schneider KW, Seeley A, Semotiuk K, Shamvil A, Sumerauer D, Toledano H, Tomboc P, Wierman M, Van Damme A, Lee YY, Zapotocky M, Bouffet E, Durno C, Aronson M, Gallinger S, Foulkes WD, Malkin D, Tabori U, Pearson CE. Functional Repair Assay for the Diagnosis of Constitutional Mismatch Repair Deficiency From Non-Neoplastic Tissue. Journal of Clinical Oncology. 2019 Feb;37(6):461.

Soberanes S, Misharin AV, Jairaman A, Morales-Nebreda L, McQuattie-Pimentel AC, Cho T, Hamanaka RB, Meliton AY, Reyfman PA, Walter JM, Chen CI, Chi M, Chiu S, Gonzalez-Gonzalez FJ, Antalek M, Abdala-Valencia H, Chiarella SE, Sun KA, Woods PS, Ghio AJ, Jain M, Perlman H, Ridge KM, Morimoto RI, Sznajder JI, Balch WE, Bhorade SM, Bharat A, Prakriya M, Chandel NS, Mutlu GM, Budinger GRS. Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis. Cell Metabolism. 2019 Feb;29(2):335.

Song B, Park SH, Zhao JC, Fong KW, Li SZ, Lee Y, Yang YA, Sridhar S, Lu XD, Abdulkadir SA, Vessella RL, Morrissey C, Kuzel TM, Catalona W, Yang XM, Yu JD. Targeting FOXA1-mediated repression of TGF-beta signaling suppresses castration-resistant prostate cancer progression. Journal of Clinical Investigation. 2019 Feb;129(2):569-582.

Tabaries S, McNulty A, Ouellet V, Annis MG, Dessureault M, Vinette M, Hachem Y, Lavoie B, Omeroglu A, Simon HG, Walsh LA, Kimbung S, Hedenfalk I, Siegel PM. Afadin cooperates with Claudin-2 to promote breast cancer metastasis. Genes & Development. 2019 Feb 1;33(3-4):180-193.

Tanimura A, Du YJ, Kondapalli J, Wokosin DL, Surmeier DJ. Cholinergic Interneurons Amplify Thalamostriatal Excitation of Striatal Indirect Pathway Neurons in Parkinson's Disease Models. Neuron. 2019 Feb;101(3):444.

Wang L, Shilatifard A. UTX Mutations in Human Cancer. Cancer Cell. 2019 Feb;35(2):168-176.

Zhang H, Brown RL, Wei Y, Zhao P, Liu S, Liu X, Deng Y, Hu X, Zhang J, Gao XD, Kang Y, Mercurio AM, Goel HL, Cheng C. CD44 splice isoform switching determines breast cancer stem cell state.Genes & Development. 2019 Feb 1;33(3-4):166-179.

Zhang S, Weinberg S, DeBerge M, Gainullina A, Schipma M, Kinchen JM, Ben-Sahra I,Gius DR, Yvan-Charvet L, Chandel NS, Schumacker PT, Thorp EB. Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair.Cell Metabolism. 2019 Feb;29(2):443.

Brown KA, Hedrick JL, Eichelsdoerfer DJ, Mirkin CA.Nanocombinatorics with Cantilever-Free Scanning Probe Arrays. ACS Nano. 2019 Jan;13(1):8-17.

Burt RK, Balabanov R, Burman J, Sharrack B, Snowden JA, Oliveira MC, Fagius J, Rose J, Nelson F, Barreira AA, Carlson K, Han XQ, Moraes D, Morgan A, Quigley K, Yaung K, Buckley R, Alldredge C, Clendenan A, Calvario MA, Henry J, Jovanovic B, Helenowski IB. Effect of Nonmyeloablative Hematopoietic Stem Cell Transplantation vs Continued Disease-Modifying Therapy on Disease Progression in Patients With Relapsing-Remitting Multiple Sclerosis A Randomized Clinical Trial. JAMA. 2019 Jan;321(2):165-174.

Carnethon MR, Neubauer LC, Greenland P. Competency-Based Postdoctoral Education. Circulation. 2019 Jan 15;139(3):310-312.

Chen SQ, Fan J, Zhang MH, Qin L, Dominguez D, Long A, Wang GX, Ma RQ, Li HB, Zhang Y, Fang DY, Sosman J, Zhang B. CD73 expression on effector T cells sustained by TGF-beta facilitates tumor resistance to anti-4-1BB/CD137 therapy. Nature Communications. 2019 Jan;10:15.

Chua KP, Fischer MA, Linder JA. Appropriateness of outpatient antibiotic prescribing among privately insured US patients: ICD-10-CM based cross sectional study. BMJ. 2019 Jan;364:8.

Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Davidson KW, Doubeni CA, Epling JW, Jr., Kemper AR, Kubik M, Landefeld CS, Mangione CM, Silverstein M, Simon MA, Tseng CW, Wong JB. Ocular Prophylaxis for Gonococcal Ophthalmia Neonatorum: US Preventive Services Task Force Reaffirmation Recommendation Statement. JAMA. 2019 Jan 29;321(4):394-398.

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