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Northwestern University Feinberg School of Medicine
Research

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Leading-edge research for breakthrough results.

Recent Publications

View the most recent publications from Feinberg faculty, updated daily.
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High-Impact Archive

Explore curated high-impact publication lists from previous years (2013-2021).
High-Impact Archive

2025 High-Impact Research

Below, browse our a curated list of faculty work from this year that was published in major academic publications.

  • Ahn J, Xie P, Chen S, Shi G, Fan J, Zhang M, Tang H, Zuckerman AR, Fang D, Wan Y, Kuzel TM, Zhang Y, Zhang B. 4-1BB stimulation with concomitant inactivation of adenosine A2B receptors enhances CD8+ T cell antitumor response. The Journal of Clinical Investigation. Jun 2025; 135(11).
  • Bachet JB, de Gramont A, Raeisi M, Rakez M, Goldberg RM, Tebbutt NC, Van Cutsem E, Haller DG, Hecht JR, Mayer RJ, Lichtman SM, Benson AB, Sobrero AF, Tabernero J, Adams R, Zalcberg JR, Grothey A, Yoshino T, André T, Shi Q, Chibaudel B. Characteristics of Patients and Prognostic Factors Across Treatment Lines in Metastatic Colorectal Cancer: An Analysis From the Aide et Recherche en Cancérologie Digestive Database. Journal of Clinical Oncology. Jun 2025; 43(18):2094-2106.
  • Bresteau E, Suva EE, Revell C, Hassan OA, Grata A, Sheridan J, Mitchell J, Arvanitis C, Korobova F, Woolner S, Jensen OE, Mitchell B. Apical size reduction by macropinocytosis alleviates tissue crowding. Nature Communications. Jun 2025; 16(1):5338-5338. 
  • Carlson DA, Pandolfino JE, Yadlapati R, Vela MF, Spechler SJ, Schnoll-Sussman FH, Lynch K, Lazarescu A, Khan A, Katz P, Jain AS, Gyawali CP, Gupta M, Garza JM, Fass R, Clarke JO, Chokshi RV, Chen J, Ravi K, Chan WW, Sultan S, Konda VJA. A Standardized Approach to Performing and Interpreting Functional Lumen Imaging Probe Panometry for Esophageal Motility Disorders: The Dallas Consensus. Gastroenterology. Jun 2025; 168(6):1114-1127.e5.
  • Chan AW, Boutron I, Hopewell S, Moher D, Schulz KF, Collins GS, Tunn R, Aggarwal R, Berkwits M, Berlin JA, Bhandari N, Butcher NJ, Campbell MK, Chidebe RCW, Elbourne DR, Farmer AJ, Fergusson DA, Golub RM, Goodman SN, Hoffmann TC, Ioannidis JPA, Kahan BC, Knowles RL, Lamb SE, Lewis S, Loder E, Offringa M, Ravaud P, Richards DP, Rockhold FW, Schriger DL, Siegfried NL, Staniszewska S, Taylor RS, Thabane L, Torgerson DJ, Vohra S, White IR, Hróbjartsson A. SPIRIT 2025 statement: updated guideline for protocols of randomized trials. Nature Medicine. Jun 2025; 31(6):1784-1792.
  • Converse A, Perry MJ, Dipali SS, Isola JVV, Kelly EB, Varberg JM, Zelinski MB, Stout MB, Pritchard MT, Duncan FE. Multinucleated giant cells are hallmarks of ovarian aging with unique immune and degradation-associated molecular signatures. PLoS Biology. Jun 2025; 23(6):e3003204-e3003204.
  • Du Y, Gu J, Duan S, Trueb J, Tzavelis A, Shin HS, Arafa H, Li X, Huang Y, Carr AN, Davies CR, Rogers JA. A skin-interfaced wireless wearable device and data analytics approach for sleep-stage and disorder detection. Proceedings of the National Academy of Sciences of the United States of America. Jun 2025; 122(23):e2501220122-e2501220122.
  • HEALEY ALS Platform Trial for the HEALEY ALS Platform Trial Study Group (including Ajroud-Driss S). Safety and efficacy of trehalose in amyotrophic lateral sclerosis (HEALEY ALS Platform Trial): an adaptive, phase 2/3, double-blind, randomised, placebo-controlled trial. The Lancet Neurology. Jun 2025; 24(6):500-511.
  • Hopewell S, Chan AW, Collins GS, Hróbjartsson A, Moher D, Schulz KF, Tunn R, Aggarwal R, Berkwits M, Berlin JA, Bhandari N, Butcher NJ, Campbell MK, Chidebe RCW, Elbourne D, Farmer A, Fergusson DA, Golub RM, Goodman SN, Hoffmann TC, Ioannidis JPA, Kahan BC, Knowles RL, Lamb SE, Lewis S, Loder E, Offringa M, Ravaud P, Richards DP, Rockhold FW, Schriger DL, Siegfried NL, Staniszewska S, Taylor RS, Thabane L, Torgerson D, Vohra S, White IR, Boutron I. CONSORT 2025 statement: updated guideline for reporting randomized trials. Nature Medicine. Jun 2025; 31(6):1776-1783.
  • Hopewell S, Chan AW, Collins GS, Hróbjartsson A, Moher D, Schulz KF, Tunn R, Aggarwal R, Berkwits M, Berlin JA, Bhandari N, Butcher NJ, Campbell MK, Chidebe RCW, Elbourne D, Farmer A, Fergusson DA, Golub RM, Goodman SN, Hoffmann TC, Ioannidis JPA, Kahan BC, Knowles RL, Lamb SE, Lewis S, Loder E, Offringa M, Ravaud P, Richards DP, Rockhold FW, Schriger DL, Siegfried NL, Staniszewska S, Taylor RS, Thabane L, Torgerson D, Vohra S, White IR, Boutron I. CONSORT 2025 Statement: Updated Guideline for Reporting Randomized Trials. Journal of the American Medical Association. Jun 2025; 333(22):1998-2005.
  • Hu VT, Ezzatpour S, Selivanovitch E, Sahler J, Pal S, Carter J, Pham QV, Adeleke RA, August A, Aguilar HC, Daniel S, Kamat NP. Cell-Free Expression of Nipah Virus Transmembrane Proteins for Proteoliposome Vaccine Design. ACS nano. Jun 2025; 19(23):21290-21306.
  • Huang R, Kratka CE, Pea J, McCann C, Nelson J, Bryan JP, Zhou LT, Russo DD, Zaniker-Gomez EJ, Gandhi AH, Shalek AK, Cleary B, Farhi SL, Duncan FE, Goods BA. Single-cell and spatiotemporal profile of ovulation in the mouse ovary. PLoS Biology. Jun 2025; 23(6):e3003193-e3003193.
  • Kelly MS, Shi P, Boiditswe SC, Qin E, Steenhoff AP, Mazhani T, Patel MZ, Cunningham CK, Rawls JF, Luinstra K, Gilchrist J, Maciejewski J, Hurst JH, Seed PC, Bulir D, Smieja M. Role of the upper airway microbiota in respiratory virus and bacterial pathobiont dynamics in the first year of life. Nature Communications. Jun 2025; 16(1):5195-5195.
  • Lamperis SM, McMahon KM, Calvert AE, Rink JS, Vasan K, Pandkar MR, Crentsil EU, Chalmers ZR, McDonald NR, Kosmala CJ, Bonini MG, Matei D, Gordon LI, Chandel NS, Thaxton CS. CRISPR screen reveals a simultaneous targeted mechanism to reduce cancer cell selenium and increase lipid oxidation to induce ferroptosis. Proceedings of the National Academy of Sciences of the United States of America. Jun 2025; 122(22):e2502876122-e2502876122.
  • Le Borgne J, Gomez L, Heikkinen S, Amin N, Ahmad S, Choi SH, Bis J, Grenier-Boley B, Rodriguez OG, Kleineidam L, Young J, Tripathi KP, Wang L, Varma A, Campos-Martin R, van der Lee S, Damotte V, de Rojas I, Palmal S, , Lipton R, Reiman E, McKee A, De Jager P, Bush W, Small S, Levey A, Saykin A, Foroud T, Albert M, Hyman B, Petersen R, Younkin S, Sano M, Wisniewski T, Vassar R, Schneider J, Henderson V, Roberson E, DeCarli C, LaFerla F, Brewer J, Swerdlow R, Van Eldik L, Hamilton-Nelson K, Paulson H, Naj A, Lopez O, Chui H, Crane P, Grabowski T, Kukull W, Asthana S, Craft S, Strittmatter S, Cruchaga C, Leverenz J, Goate A, Kamboh MI, George-Hyslop PS, Valladares O, Kuzma A, Cantwell L, Riemenschneider M, Morris J, Slifer S, Dalmasso C, Castillo A, Küçükali F, Peters O, Schneider A, Dichgans M, Rujescu D, Scherbaum N, Deckert J, Riedel-Heller S, Hausner L, Molina-Porcel L, Düzel E, Grimmer T, Wiltfang J, Heilmann-Heimbach S, Moebus S, Tegos T, Scarmeas N, Dols-Icardo O, Moreno F, Pérez-Tur J, Bullido MJ, Pastor P, Sánchez-Valle R, Álvarez V, Boada M, García-González P, Puerta R, Mir P, Real LM, Piñol-Ripoll G, García-Alberca JM, Royo JL, Rodriguez-Rodriguez E, Soininen H, de Mendonça A, Mehrabian S, Traykov L, Hort J, Vyhnalek M, Thomassen JQ, Pijnenburg YAL, Holstege H, van Swieten J, Ramakers I, Verhey F, Scheltens P, Graff C, Papenberg G, Giedraitis V, Boland A, Deleuze JF, Nicolas G, Dufouil C, Pasquier F, Hanon O, Debette S, Grünblatt E, Popp J, Ghidoni R, Galimberti D, Arosio B, Mecocci P, Solfrizzi V, Parnetti L, Squassina A, Tremolizzo L, Borroni B, Nacmias B, Spallazzi M, Seripa D, Rainero I, Daniele A, Bossù P, Masullo C, Rossi G, Jessen F, Fernandez V, Kehoe PG, Frikke-Schmidt R, Tsolaki M, Sánchez-Juan P, Sleegers K, Ingelsson M, Haines J, Farrer L, Mayeux R, Wang LS, Sims R, DeStefano A, Schellenberg GD, Seshadri S, Amouyel P, Williams J, van der Flier W, Ramirez A, Pericak-Vance M, Andreassen OA, Van Duijn C, Hiltunen M, Ruiz A, Dupuis J, Martin E, Lambert JC, Kunkle B, Bellenguez C. X-chromosome-wide association study for Alzheimer's disease. Molecular Psychiatry. Jun 2025; 30(6):2335-2346. 
  • Lentz RJ, Frederick-Dyer K, Planz VB, Koyama T, Aboudara MC, Avasarala SK, Casey JD, Cheng GZ, D'Haese PF, Duke JD, Grogan EL, Hoopman TC, Johnson J, Katsis JM, Kurman JS, Low SW, Mahmood K, Rickman OB, Roller L, Salmon C, Shojaee S, Swanner B, Wahidi MM, Walston C, Silvestri GA, Yarmus L, Rahman NM, Maldonado F. Navigational Bronchoscopy or Transthoracic Needle Biopsy for Lung Nodules. The New England Journal of Medicine. Jun 2025; 392(21):2100-2112. doi:10.1056/NEJMoa2414059
  • Li Y, Ding Y, Dennis S, Hutch MR, Zhou J, Zhou Y, Li Y, Pillai M, Ghotbaldini S, Garcia MA, Broad MS, Mao C, Dulai PS, Cheng F, Zeng Z, Luo Y. SOAR elucidates biological insights and empowers drug discovery through spatial transcriptomics. Science Advances. Jun 2025; 11(24):eadt7450-eadt7450.
  • Lindau ST, Makelarski JA, Winslow VA, Abramsohn EM, Anand V, Burnet DL, Fuller CM, Grana M, Miller DC, Ren ES, Waxman E, Wroblewski KE. Low-Intensity Social Care and Child Acute Health Care Utilization: A Randomized Clinical Trial. JAMA Pediatrics. Jun 2025; 179(6):610-620.
  • Lindman BR, Pibarot P, Schwartz A, Oldemeyer JB, Su YR, Goel K, Cohen DJ, Fearon WF, Babaliaros V, Daniels D, Chhatriwalla A, Suradi HS, Shah P, Szerlip M, Mack MJ, Dahle T, O'Neill WW, Davidson CJ, Makkar R, Sheth T, Depta J, DeVries JT, Southard J, Pop A, Sorajja P, Hahn RT, Zhao Y, Leon MB, Généreux P. Cardiac Biomarkers in Patients With Asymptomatic Severe Aortic Stenosis: Analysis From the EARLY TAVR Trial. Circulation. Jun 2025; 151(22):1550-1564.
  • Pace JA, Goddard LM, Hong CC, Wang L, Yang J, Chen M, Xu Y, Dominguez MH, Gao S, Chen X, Mericko-Ishizuka P, Tan C, Kume T, Yu W, Tan K, Hancock WW, Ferrari G, Kahn ML. Hemodynamic forces prevent myxomatous valve disease in mice through KLF2/4 signaling. The Journal of Clinical Investigation. Jun 2025; 135(12). 
  • Palomero OE, Guadarrama E, DeCaen PG. Pathogenic variants in the polycystin pore helix cause distinct forms of channel dysfunction. Proceedings of the National Academy of Sciences of the United States of America. Jun 2025; 122(24):e2421362122-e2421362122.
  • Queathem ED, Stagg DB, Nelson AB, Chaves AB, Crown SB, Fulghum K, d'Avignon DA, Ryder JR, Bolan PJ, Hayir A, Gillingham JR, Jannatpour S, Rome FI, Williams AS, Muoio DM, Ikramuddin S, Hughey CC, Puchalska P, Crawford PA. Ketogenesis mitigates metabolic dysfunction-associated steatotic liver disease through mechanisms that extend beyond fat oxidation. The Journal of Clinical Investigation. Jun 2025; 135(12).
  • Rosas-Vidal LE, Naskar S, Mayo LM, Perini I, Masroor R, Altemus M, Ramos-Medina L, Zaidi SD, Engelbrektsson H, Jagasia P, Heilig M, Patel S. Prefrontal correlates of fear generalization during endocannabinoid depletion. The Journal of Clinical Investigation. Jun 2025; 135(11). 
  • Sperduto PW, Marqueen KE, Chang E, Li J, Davies MA, Ebner DK, Breen WG, Lamba N, Shih HA, Edwards D, Kim MM, Mahal A, Rahman R, Ankrah N, Boggs DH, Lewis C, Hyer D, Buatti JM, Johri F, Soliman H, Masucci L, Roberge D, Aneja S, Chiang V, Phuong C, Braunstein S, Dajani S, Sachdev S, Wan Z, Niedzwiecki D, Vaios E, Kirkpatrick JP, Pasetsky J, Wang TJC, Kutuk T, Kotecha R, Ross RB, Rusthoven CG, Nakano T, Tawbi HA, Mehta MP. Improved Survival and Prognostication in Melanoma Patients With Brain Metastases: An Update of the Melanoma Graded Prognostic Assessment. Journal of Clinical Oncology. Jun 2025; 43(16):1910-1919.
  • Strom NI, Gerring ZF, Galimberti M, Yu D, Halvorsen MW, Abdellaoui A, Rodriguez-Fontenla C, Sealock JM, Bigdeli T, Coleman JR, Mahjani B, Thorp JG, Bey K, Burton CL, Luykx JJ, Zai G, Alemany S, Andre C, Askland KD, Bäckman J, Banaj N, Barlassina C, Nissen JB, Bienvenu OJ, Black D, Bloch MH, Børte S, Bosch R, Breen M, Brennan BP, Brentani H, Buxbaum JD, Bybjerg-Grauholm J, Byrne EM, Cabana-Dominguez J, Camarena B, Camarena A, Cappi C, Carracedo A, Casas M, Cavallini MC, Ciullo V, Cook EH, Crosby J, Cullen BA, De Schipper EJ, Delorme R, Djurovic S, Elias JA, Estivill X, Falkenstein MJ, Fundin BT, Garner L, Gironda C, Goes FS, Grados MA, Grove J, Guo W, Haavik J, Hagen K, Harrington K, Havdahl A, Höffler KD, Hounie AG, Hucks D, Hultman C, Janecka M, Jenike E, Karlsson EK, Kelley K, Klawohn J, Krasnow JE, Krebs K, Lange C, Lanzagorta N, Levey D, Lindblad-Toh K, Macciardi F, Maher B, Mathes B, McArthur E, McGregor N, McLaughlin NC, Meier S, Miguel EC, Mulhern M, Nestadt PS, Nurmi EL, O'Connell KS, Osiecki L, Ousdal OT, Palviainen T, Pedersen NL, Piras F, Piras F, Potluri S, Rabionet R, Ramirez A, Rauch S, Reichenberg A, Riddle MA, Ripke S, Rosário MC, Sampaio AS, Schiele MA, Skogholt AH, Sloofman LG, Smit J, Artigas MS, Thomas LF, Tifft E, Vallada H, van Kirk N, Veenstra-VanderWeele J, Vulink NN, Walker CP, Wang Y, Wendland JR, Winsvold BS, Yao Y, Zhou H, ,  , Agrawal A, Alonso P, Berberich G, Bucholz KK, Bulik CM, Cath D, Denys D, Eapen V, Edenberg H, Falkai P, Fernandez TV, Fyer AJ, Gaziano JM, Geller DA, Grabe HJ, Greenberg BD, Hanna GL, Hickie IB, Hougaard DM, Kathmann N, Kennedy J, Lai D, Landén M, Hellard SL, Leboyer M, Lochner C, McCracken JT, Medland SE, Mortensen PB, Neale BM, Nicolini H, Nordentoft M, Pato M, Pato C, Pauls DL, Piacentini J, Pittenger C, Posthuma D, Ramos-Quiroga JA, Rasmussen SA, Richter MA, Rosenberg DR, Ruhrmann S, Samuels JF, Sandin S, Sandor P, Spalletta G, Stein DJ, Stewart SE, Storch EA, Stranger BE, Turiel M, Werge T, Andreassen OA, Børglum AD, Walitza S, Hveem K, Hansen BK, Rück C, Martin NG, Milani L, Mors O, Reichborn-Kjennerud T, Ribasés M, Kvale G, Mataix-Cols D, Domschke K, Grünblatt E, Wagner M, Zwart JA, Breen G, Nestadt G, Kaprio J, Arnold PD, Grice DE, Knowles JA, Ask H, Verweij KJ, Davis LK, Smit DJ, Crowley JJ, Scharf JM, Stein MB, Gelernter J, Mathews CA, Derks EM, Mattheisen M. Genome-wide analyses identify 30 loci associated with obsessive-compulsive disorder. Nature Genetics. Jun 2025; 57(6):1389-1401.
  • Wang H, Hu D, Cheng Y, Gao Q, Liu K, Mani NL, Tang AY, Iyer R, Gao B, Sun L, Zhou Q, Yu Q, Weinberg SE, Zhang X, Cong Y, Dulai PS, Zhang Y, Liu Z, Fang D. Succinate drives gut inflammation by promoting FOXP3 degradation through a molecular switch. Nature Immunology. Jun 2025; 26(6):866-880.
  • Wuliji N, Jones SMW, Gooley T, Gerds AT, Medeiros BC, Shami PJ, Galvin J, Adekola K, Luger S, Baer MR, Rizzieri D, Wildes TM, Wang ES, Sekeres MA, Mukherjee S, Smith J, Garrison M, Kojouri K, Appelbaum J, Percival ME, Sandmaier BM, Lee S, Appelbaum FR, Rouce R, Sorror ML. Social determinants of health and access to allogeneic hematopoietic cell transplantation for acute myeloid leukemia. Blood. Jun 2025; 145(25):3041-3051.
  • Yin X, Pu Y, Yuan S, Pache L, Churas C, Weston S, Riva L, Simons LM, Cisneros WJ, Clausen T, Biddle G, Doss-Gollin S, Deming M, De Jesus PD, Kim HN, Fuentes D, Whitelock JM, Esko JD, Lord MS, Mena I, García-Sastre A, Hultquist JF, Frieman MB, Ideker T, Pratt D, Martin-Sancho L, Chanda SK. Global siRNA screen identifies human host factors critical for SARS-CoV-2 replication and late stages of infection. PLoS Biology. Jun 2025; 23(6):e3002738-e3002738.
  • Zhou J, Hepperla A, Simon JM, Kim K, Hu Q, Zhang C, Dong L, Hu L, Zhang C, Liao C, Fang A, Adachi Y, Fu H, Wang T, Liang Q, Zhao F, Liu H, Takeda M, Fang J, Zhong H, Ly P, Wang L, Kapur P, Xu L, Jia L, Malladi S, Brugarolas J, Simon MC, Li B, Zhang Q. SWI/SNF ATPase silenced HLF potentiates lung metastasis in solid cancers. Nature Communications. Jun 2025; 16(1):5226-5226.
  • Basch E, Schrag D, Jansen J, Henson S, Ginos B, Stover AM, Carr P, Spears PA, Jonsson M, Deal AM, Bennett AV, Thanarajasingam G, Rogak L, Reeve BB, Snyder C, Bruner D, Cella D, Kottschade LA, Perlmutter J, Geoghegan C, Given B, Mazza GL, Miller R, Strasser JF, Zylla DM, Weiss A, Blinder VS, Wolf AP, Dueck AC. Symptom monitoring with electronic patient-reported outcomes during cancer treatment: final results of the PRO-TECT cluster-randomized trial. Nature Medicine. Apr 2025; 31(4):1225-1232. doi:10.1038/s41591-025-03507-y
  • Chaikin CA, Thakkar AV, Steffeck AWT, Pfrender EM, Hung K, Zhu P, Waldeck NJ, Nozawa R, Song W, Futtner CR, Quattrocelli M, Bass J, Ben-Sahra I, Peek CB. Control of circadian muscle glucose metabolism through the BMAL1-HIF axis in obesity. Proceedings Of The National Academy Of Sciences Of The United States Of America. Apr 2025; 122(13):e2424046122-e2424046122. doi:10.1073/pnas.2424046122
  • Chan AW, Boutron I, Hopewell S, Moher D, Schulz KF, Collins GS, Tunn R, Aggarwal R, Berkwits M, Berlin JA, Bhandari N, Butcher NJ, Campbell MK, Chidebe RCW, Elbourne DR, Farmer AJ, Fergusson DA, Golub RM, Goodman SN, Hoffmann TC, Ioannidis JPA, Kahan BC, Knowles RL, Lamb SE, Lewis S, Loder E, Offringa M, Ravaud P, Richards DP, Rockhold FW, Schriger DL, Siegfried NL, Staniszewska S, Taylor RS, Thabane L, Torgerson DJ, Vohra S, White IR, Hróbjartsson A. SPIRIT 2025 statement: Updated guideline for protocols of randomised trials. Plos Medicine. Apr 2025; 22(4):e1004589-e1004589. doi:10.1371/journal.pmed.1004589
  • Chan AW, Boutron I, Hopewell S, Moher D, Schulz KF, Collins GS, Tunn R, Aggarwal R, Berkwits M, Berlin JA, Bhandari N, Butcher NJ, Campbell MK, Chidebe RCW, Elbourne DR, Farmer AJ, Fergusson DA, Golub RM, Goodman SN, Hoffmann TC, Ioannidis JPA, Kahan BC, Knowles RL, Lamb SE, Lewis S, Loder E, Offringa M, Ravaud P, Richards DP, Rockhold FW, Schriger DL, Siegfried NL, Staniszewska S, Taylor RS, Thabane L, Torgerson DJ, Vohra S, White IR, Hróbjartsson A. SPIRIT 2025 statement: updated guideline for protocols of randomised trials. BMJ. Apr 2025; 389():e081477-e081477. doi:10.1136/bmj-2024-081477
  • Chen J, Goerdeler F, Jaroentomeechai T, Hernandez FXS, Wang X, Clausen H, Narimatsu Y, Satchell KJF. Vibrio MARTX toxin binding of biantennary N-glycans at host cell surfaces. Science Advances. Apr 2025; 11(15):eadt0063-eadt0063. doi:10.1126/sciadv.adt0063
  • Chi JJ, Xie P, Cheng MH, Zhu Y, Cui X, Watson J, Zeng L, Uddin A, Nguyen H, Li L, Moremen K, Reedy A, Wyatt M, Marcus A, Dai M, Paulos CM, Cristofanilli M, Gradishar WJ, Zhao S, Kalinsky K, Hung MC, Bahar I, Zhang B, Wan Y. MGAT1-Guided complex N-Glycans on CD73 regulate immune evasion in triple-negative breast cancer. Nature Communications. Apr 2025; 16(1):3552-3552. doi:10.1038/s41467-025-58524-9
  • Detomasi TC, Degotte G, Huang S, Suryawanshi RK, Diallo A, Lizzadro L, Zaptero-Belinchón FJ, Taha TY, Li J, Richards AL, Hantz ER, Alam Z, Montano M, McCavitt-Malvido M, Gumpena R, Partridge JR, Correy GJ, Matsui Y, Charvat AF, Glenn IS, Rosecrans J, Revalde JL, Anderson D, Hultquist JF, Arkin MR, Neitz RJ, Swaney DL, Krogan NJ, Shoichet BK, Verba KA, Ott M, Renslo AR, Craik CS. Structure-based discovery of highly bioavailable, covalent, broad-spectrum coronavirus M Pro inhibitors with potent in vivo efficacy. Science Advances. Apr 2025; 11(17):eadt7836-eadt7836. doi:10.1126/sciadv.adt7836
  • Foss FM, Kim YH, Prince HM, Akilov OE, Querfeld C, Seminario-Vidal L, Fisher DC, Kuzel TM, Yannakou CK, Geskin LJ, Feldman T, Sokol L, Allen PB, Dang NH, Cabanillas F, Wong HK, Ooi CE, Xing D, Sauter N, Singh P, Czuczman M, Duvic M. Efficacy and Safety of Denileukin Diftitox-Cxdl, an Improved Purity Formulation of Denileukin Diftitox, in Patients With Relapsed or Refractory Cutaneous T-Cell Lymphoma. Journal of Clinical Oncology. Apr 2025; 43(10):1198-1209. doi:10.1200/JCO-24-01549
  • Gabby ME, Bandara A, Outrata LM, Ebohon O, Ahmad SS, Dressler JM, McClune ME, Trimble RN, Mullen L, Jutras BL. A high-resolution screen identifies a preexisting beta-lactam that specifically treats Lyme disease in mice. Science Translational Medicine. Apr 2025; 17(795):eadr9091-eadr9091. doi:10.1126/scitranslmed.adr9091
  • Goyal M, Ospel JM, Ganesh A, Dowlatshahi D, Volders D, Möhlenbruch MA, Jumaa MA, Nimjee SM, Booth TC, Buck BH, Kennedy J, Shankar JJ, Dorn F, Zhang L, Hametner C, Nardai S, Zafar A, Diprose W, Vatanpour S, Stebner A, Bosshart S, Singh N, Sebastian I, Uchida K, Ryckborst KJ, Fahed R, Hu SX, Vollherbst DF, Zaidi SF, Lee VH, Lynch J, Rempel JL, Teal R, Trivedi A, Bode FJ, Ogungbemi A, Pham M, Orosz P, Abdalkader M, Taschner C, Tarpley J, Poli S, Singh RJ, De Leacy R, Lopez G, Sahlas D, Chen M, Burns P, Schaafsma JD, Marigold R, Reich A, Amole A, Field TS, Swartz RH, Settecase F, Lenzsér G, Ortega-Gutierrez S, Asdaghi N, Lobotesis K, Siddiqui AH, Berrouschot J, Mokin M, Ebersole K, Schneider H, Yoo AJ, Mandzia J, Klostranec J, Jadun C, Patankar T, Sauvageau E, Lenthall R, Peeling L, Huynh T, Budzik R, Lee SK, Makalanda L, Levitt MR, Perry RJ, Hlaing T, Jahromi BS, Singh P, Demchuk AM, Hill MD. Endovascular Treatment of Stroke Due to Medium-Vessel Occlusion. The New England Journal of Medicine. Apr 2025; 392(14):1385-1395. doi:10.1056/NEJMoa2411668
  • Hopewell S, Chan AW, Collins GS, Hróbjartsson A, Moher D, Schulz KF, Tunn R, Aggarwal R, Berkwits M, Berlin JA, Bhandari N, Butcher NJ, Campbell MK, Chidebe RCW, Elbourne D, Farmer A, Fergusson DA, Golub RM, Goodman SN, Hoffmann TC, Ioannidis JPA, Kahan BC, Knowles RL, Lamb SE, Lewis S, Loder E, Offringa M, Ravaud P, Richards DP, Rockhold FW, Schriger DL, Siegfried NL, Staniszewska S, Taylor RS, Thabane L, Torgerson D, Vohra S, White IR, Boutron I. CONSORT 2025 statement: updated guideline for reporting randomised trials. BMJ. Apr 2025; 389():e081123-e081123. doi:10.1136/bmj-2024-081123
  • Hopewell S, Chan AW, Collins GS, Hróbjartsson A, Moher D, Schulz KF, Tunn R, Aggarwal R, Berkwits M, Berlin JA, Bhandari N, Butcher NJ, Campbell MK, Chidebe RCW, Elbourne D, Farmer A, Fergusson DA, Golub RM, Goodman SN, Hoffmann TC, Ioannidis JPA, Kahan BC, Knowles RL, Lamb SE, Lewis S, Loder E, Offringa M, Ravaud P, Richards DP, Rockhold FW, Schriger DL, Siegfried NL, Staniszewska S, Taylor RS, Thabane L, Torgerson D, Vohra S, White IR, Boutron I. CONSORT 2025 explanation and elaboration: updated guideline for reporting randomised trials. BMJ. Apr 2025; 389():e081124-e081124. doi:10.1136/bmj-2024-081124
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