Northwestern University Feinberg School of Medicine
Research

High-Impact-Factor Research 2018

Aubert G, Ajroud-Driss S, Knight BP, Shah SJ, McNally EM. New DEStiny Revealed: Young Woman Postablation for Wolf-Parkinson-White Syndrome With Recurrent Syncope and Progressive Myopathy. Circulation. 2018 Sep;138(12):1267-1271.

Braun R, Kath WL, Iwanaszko M, Kula-Eversole E, Abbott SM, Reid KJ, Zee PC, Allada R.Universal method for robust detection of circadian state from gene expression. Proceedings of the National Academy of Sciences of the United States of America. 2018 Sep;115(39):E9247-E9256.

Cajigas I, Chakraborty A, Swyter KR, Luo H, Bastidas M, Nigro M, Morris ER, Chen S, VanGompel MJW, Leib D, Kohtz SJ, Martina M, Koh S, Ay F, Kohtz JD. The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially Organizes Megabase Distant Genes in the Developing Forebrain. Molecular Cell. 2018 Sep;71(6):956.

Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Davidson K, Doubeni CA, Epling JW, Grossman DC, Kemper AR, Kubik M, Landefeld CS, Mangione CM, Phipps MG, Silverstein M, Simon MA, Tseng CW, Wong JB, Force USPST. Behavioral Weight Loss Interventions to Prevent Obesity-Related Morbidity and Mortality in Adults US Preventive Services Task Force Recommendation Statement. JAMA. 2018 Sep;320(11):1163-1171.

Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Davidson KW, Doubeni CA, Epling JW, Kemper AR, Kubik M, Kurth AE, Landefeld CS, Mangione CM, Phipps MG, Silverstein M, Simon MA, Tseng CW, Wong JB, Force USPST. Screening for Syphilis Infection in Pregnant Women US Preventive Services Task Force Reaffirmation Recommendation Statement. JAMA. 2018 Sep;320(9):911-917.

Dekleva BM, Kording KP, Miller LE.Single reach plans in dorsal premotor cortex during a two-target task. Nature Communications. 2018 Sep;9:12.

Jalal H, Buchanich JM, Roberts MS, Balmert LC, Zhang K, Burke DS. Changing dynamics of the drug overdose epidemic in the United States from 1979 through 2016. Science. 2018 Sep;361(6408):1218.

Jong SJ, Crequer A, Matos I, Hum D, Gunasekharan V, Lorenzo L, Jabot-Hanin F, Imahorn E, Arias AA, Vahidnezhad H, Youssefian L, Markle JG, Patin E, D'Amico A, Wang CQF, Full F, Ensser A, Leisner TM, Parise LV, Bouaziz M, Maya N, Cadena X, Saka B, Saeidian AH, Aghazadeh N, Zeinali S, Itin P, Krueger JG, Laimins L, Abel L, Fuchs E, Uitto J, Franco J, Burger B, Orth G, Jouanguy E, Casanova JL. The human CIB1-EVER1-EVER2 complex governs keratinocyte-intrinsic immunity to beta-papillomaviruses. Journal of Experimental Medicine. 2018 Sep;215(9):2289-2310.

Kam CY, Dubash AD, Magistrati E, Polo S, Satchell KJF, Sheikh F, Lampe PD, Green KJ.Desmoplakin maintains gap junctions by inhibiting Ras/MAPK and lysosomal degradation of connexin-43. Journal of Cell Biology. 2018 Sep;217(9):3219-3235.

Kim YH, Bagot M, Pinter-Brown L, Rook AH, Porcu P, Horwitz SM, Whittaker S, Tokura Y, Vermeer M, Zinzani PL, Sokol L, Morris S, Kim EJ, Ortiz-Romero PL, Eradat H, Scarisbrick J, Tsianakas A, Elmets C, Dalle S, Fisher DC, Halwani A, Poligone B, Greer J, Fierro MT, Khot A, Moskowitz AJ, Musiek A, Shustov A, Pro B, Geskin LJ, Dwyer K, Moriya J, Leoni M, Humphrey JS, Hudgens S, Grebennik DO, Tobinai K, Duvic M, Investigators M. Mogamulizumab versus vorinostat in previously treated cutaneous T-cell lymphoma (MAVORIC): an international, open-label, randomised, controlled phase 3 trial. Lancet Oncology. 2018 Sep;19(9):1192-1204.

Liu P, Thomson BR, Khalatyan N, Feng L, Liu XR, Savas JN, Quaggin SE, Jin J.Selective permeability of mouse blood-aqueous barrier as determined by N-15-heavy isotope tracing and mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America. 2018 Sep;115(36):9032-9037.

Liu XL, Zhang ZH, Wang LQ, Yakobson BI, Hersam MC. Intermixing and periodic self-assembly of borophene line defects. Nature Materials. 2018 Sep;17(9):783.

Lowe WL, Scholtens DM, Lowe LP, Kuang A, Nodzenski M, Talbot O, Catalano PM, Linder B, Brickman WJ, Clayton P, Deerochanawong C, Hamilton J, Josefson JL, Lashley M, Lawrence JM, Lebenthal Y, Ma R, Maresh M, McCance D, Tam WH, Sacks DA, Dyer AR, Metzger BE, Hapo Follow-Up Study Cooperative R. Association of Gestational Diabetes With Maternal Disorders of Glucose Metabolism and Childhood Adiposity. JAMA. 2018 Sep;320(10):1005-1016.

Maurer MS, Schwartz JH, Gundapaneni B, Elliott PM, Merlini G, Waddington-Cruz M, Kristen AV, Grogan M, Witteles R, Damy T, Drachman BM, Shah SJ, Hanna M, Judge DP, Barsdorf AI, Huber P, Patterson TA, Riley S, Schumacher J, Stewart M, Sultan MB, Rapezzi C, Investigators A-AS. Tafamidis Treatment for Patients with Transthyretin Amyloid Cardiomyopathy. New England Journal of Medicine. 2018 Sep;379(11):1007-1016.

McGurk L, Gomes E, Guo L, Mojsilovic-Petrovic J, Tran V, Kalb RG, Shorter J, Bonini NM. Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization. Molecular Cell. 2018 Sep;71(5):703.

Miller KD, O'Neill A, Gradishar W, Hobday TJ, Goldstein LJ, Mayer IA, Bloom S, Brufsky AM, Tevaarwerk AJ, Sparano JA, Le-Lindqwister NA, Hendricks CB, Northfelt DW, Dang CT, Sledge GW, Jr. Double-Blind Phase III Trial of Adjuvant Chemotherapy With and Without Bevacizumab in Patients With Lymph Node-Positive and High-Risk Lymph Node-Negative Breast Cancer (E5103). Journal of Clinical Oncology. 2018 Sep 1;36(25):2621-2629.

Ou-Yang MH, Kurz JE, Nomura T, Popovic J, Rajapaksha TW, Dong H, Contractor A, Chetkovich DM, Tourtellotte WG, Vassar R.Axonal organization defects in the hippocampus of adult conditional BACE1 knockout mice. Science Translational Medicine. 2018 Sep;10(459):15.

Poulin JF, Caronia G, Hofer C, Cui QL, Helm B, Ramakrishnan C, Chan CS, Dombeck DA, Deisseroth K, Awatramani R.Mapping projections of molecularly defined dopamine neuron subtypes using intersectional genetic approaches. Nature Neuroscience. 2018 Sep;21(9):1260.

Seifert HS.Above and Beyond Watson and Crick: Guanine Quadruplex Structures and Microbes. Annual Review of Microbiology. 2018 Sep 8;72:49-69.

Shigemura M, Lecuona E, Angulo M, Homma T, Rodriguez DA, Gonzalez-Gonzalez FJ, Welch LC, Amarelle L, Kim SJ, Kaminski N, Budinger GRS, Solway J, Sznajder JI. Hypercapnia increases airway smooth muscle contractility via caspase-7-mediated miR-133a-RhoA signaling. Science Translational Medicine. 2018 Sep;10(457):14.

Stoeger T, Gerlach M, Morimoto RI, Nunes Amaral LA. Large-scale investigation of the reasons why potentially important genes are ignored. PLoS Biology. 2018 Sep;16(9):e2006643.

Sun C, Shen M, Chavez AD, Evans AM, Liu XL, Harutyunyan B, Flanders NC, Hersam MC, Bedzyk MJ, de la Cruz MO, Dichtel WR. High aspect ratio nanotubes assembled from macrocyclic iminium salts. Proceedings of the National Academy of Sciences of the United States of America. 2018 Sep;115(36):8883-8888.

Vachon-Presseau E, Berger SE, Abdullah TB, Huang LJ, Cecchi GA, Griffith JW, Schnitzer TJ, Apkarian AV.Brain and psychological determinants of placebo pill response in chronic pain patients. Nature Communications. 2018 Sep;9:15.

Wei JC, Yuan YZ, Chen L, Xu YM, Zhang YH, Wang YJ, Yang YJ, Peek CB, Diebold L, Yang Y, Gao BX, Jin CZ, Melo-Cardenas J, Chandel NS, Zhang DD, Pan H, Zhang KZ, Wang J, He FC, Fang DY. ER-associated ubiquitin ligase HRD1 programs liver metabolism by targeting multiple metabolic enzymes. Nature Communications. 2018 Sep;9:14.

Zhao N, Sebastiano V, Moshkina N, Mena N, Hultquist J, Jimenez-Morales D, Ma YX, Rialdi A, Albrecht R, Fenouil R, Sanchez-Aparicio MT, Ayllon J, Ravisankar S, Haddad B, Ho JSY, Low D, Jin J, Yurchenko V, Prinjha RK, Tarakhovsky A, Squatrito M, Pinto D, Allette K, Byun M, Smith ML, Sebra R, Guccione E, Tumpey T, Krogan N, Greenbaum B, van Bakel H, Garcia-Sastre A, Marazzi I. Influenza virus infection causes global RNAPII termination defects.Nature Structural & Molecular Biology. 2018 Sep;25(9):885.

Zimmer B, Ewaleifoh O, Harschnitz O, Lee YS, Peneau C, McAlpine JL, Liu B, Tchieu J, Steinbeck JA, Lafaille F, Volpi S, Notarangelo LD, Casanova JL, Zhang SY, Smith GA, Studer L. Human iPSC-derived trigeminal neurons lack constitutive TLR3-dependent immunity that protects cortical neurons from HSV-1 infection. Proceedings of the National Academy of Sciences of the United States of America. 2018 Sep;115(37):E8775-E8782.

Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Davidson KW, Doubeni CA, Epling JW, Kemper AR, Kubik M, Landefeld CS, Mangione CM, Phipps MG, Silverstein M, Simon MA, Tseng CW, Wong JB, Force USPST. Screening for Cervical Cancer US Preventive Services Task Force Recommendation Statement. JAMA. 2018 Aug;320(7):674-686.

Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Davidson KW, Doubeni CA, Epling JW, Kemper AR, Kubik M, Landefeld CS, Mangione CM, Silverstein M, Simon MA, Tseng CW, Wong JB, Us Preventive Services Task F. Screening for Atrial Fibrillation With Electrocardiography US Preventive Services Task Force Recommendation Statement. JAMA. 2018 Aug;320(5):478-484.

Fox RJ, Coffey CS, Conwit R, Cudkowicz ME, Gleason T, Goodman A, Klawiter EC, Matsuda K, McGovern M, Naismith RT, Ashokkumar A, Barnes J, Ecklund D, Klingner E, Koepp M, Long JD, Natarajan S, Thornell B, Yankey J, Bermel RA, Debbins JP, Huang X, Jagodnik P, Lowe MJ, Nakamura K, Narayanan S, Sakaie KE, Thoomukuntla B, Zhou X, Krieger S, Alvarez E, Apperson M, Bashir K, Cohen BA, Coyle PK, Delgado S, Dewitt LD, Flores A, Giesser BS, Goldman MD, Jubelt B, Lava N, Lynch SG, Moses H, Ontaneda D, Perumal JS, Racke M, Repovic P, Riley CS, Severson C, Shinnar S, Suski V, Weinstock-Guttman B, Yadav V, Zabeti A. Phase 2 Trial of Ibudilast in Progressive Multiple Sclerosis. New England Journal of Medicine. 2018 Aug 30;379(9):846-855.

Ghosn J, Taiwo B, Seedat S, Autran B, Katlama C. HIV. Lancet. 2018 Aug;392(10148):685-697.

Grobman WA, Rice MM, Reddy UM, Tita ATN, Silver RM, Mallett G, Hill K, Thom EA, El-Sayed YY, Perez-Delboy A, Rouse DJ, Saade GR, Boggess KA, Chauhan SP, Iams JD, Chien EK, Casey BM, Gibbs RS, Srinivas SK, Swamy GK, Simhan HN, Macones GA, Eunice Kennedy Shriver Natl Inst C. Labor Induction versus Expectant Management in Low-Risk Nulliparous Women. New England Journal of Medicine. 2018 Aug;379(6):513-523.

Hlubocky FJ, Sachs GA, Larson ER, Nimeiri HS, Cella D, Wroblewski KE, Ratain MJ, Peppercorn JM, Daugherty CK. Do Patients With Advanced Cancer Have the Ability to Make Informed Decisions for Participation in Phase I Clinical Trials?Journal of Clinical Oncology. 2018 Aug 20;36(24):2483-2491.

Loftfield E, Cornelis MC, Caporaso N, Yu K, Sinha R, Freedman N. Association of Coffee Drinking With Mortality by Genetic Variation in Caffeine Metabolism Findings From the UK Biobank. JAMA Internal Medicine. 2018 Aug;178(8):1086-1097.

Manzano M, Patil A, Waldrop A, Dave SS, Behdad A, Gottwein E. Gene essentiality landscape and druggable oncogenic dependencies in herpesviral primary effusion lymphoma. Nature Communications. 2018 Aug;9:14.

Mayne SL, Widome R, Carroll AJ, Schreiner PJ, Gordon-Larsen P, Jacobs DR, Kershaw KN. Longitudinal Associations of Smoke-Free Policies and Incident Cardiovascular Disease: CARDIA Study. Circulation. 2018 Aug;138(6):557-566.

Meade N, Furey C, Li H, Verma R, Chai QQ, Rollins MG, DiGiuseppe S, Naghavi MH, Walsh D.Poxviruses Evade Cytosolic Sensing through Disruption of an mTORC1-mTORC2 Regulatory Circuit.Cell. 2018 Aug;174(5):1143.

Mente A, O'Donnell M, Rangarajan S, McQueen M, Dagenais G, Wielgosz A, Lear S, Ah STL, Wei L, Diaz R, Avezum A, Lopez-Jaramillo P, Lanas F, Mony P, Szuba A, Iqbal R, Yusuf R, Mohammadifard N, Khatib R, Yusoff K, Ismail N, Gulec S, Rosengren A, Yusufali A, Kruger L, Tsolekile LP, Chifamba J, Dans A, Alhabib KF, Yeates K, Teo K, Yusuf S. Urinary sodium excretion, blood pressure, cardiovascular disease, and mortality: a community-level prospective epidemiological cohort study. Lancet. 2018 Aug;392(10146):496-506.

Mosley JD, Feng QP, Wells QS, Van Driest SL, Shaffer CM, Edwards TL, Bastarache L, Wei WQ, Davis LK, McCarty CA, Thompson W, Chute CG, Jarvik GP, Gordon AS, Palmer MR, Crosslin DR, Larson EB, Carrell DS, Kullo IJ, Pacheco JA, Peissig PL, Brilliant MH, Linneman JG, Namjou B, Williams MS, Ritchie MD, Borthwick KM, Verma SS, Karnes JH, Weiss ST, Wang TJ, Stein CM, Denny JC, Roden DM. A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers. Nature Communications. 2018 Aug;9:11.

Naghavi M, Marczak LB, Kutz M, et al. (including Swaroop, M). Global Mortality From Firearms, 1990-2016. JAMA. 2018 Aug;320(8):792-814.

Persell SD, Karmali KN, Lazar D, Friesema EM, Lee JY, Rademaker A, Kaiser D, Eder M, French DD, Brown T, Wolf MS. Effect of Electronic Health Record-Based Medication Support and Nurse-Led Medication Therapy Management on Hypertension and Medication Self-management A Randomized Clinical Trial. JAMA Internal Medicine. 2018 Aug;178(8):1069-1077.

Sonoda T, Lee SK, Birnbaumer L, Schmidt TM. Melanopsin Phototransduction Is Repurposed by ipRGC Subtypes to Shape the Function of Distinct Visual Circuits. Neuron. 2018 Aug;99(4):754.

Wu H, Rahman HNA, Dong Y, Liu X, Lee Y, Wen A, To KH, Xiao L, Birsner AE, Bazinet L, Wong S, Song K, Brophy ML, Mahamud MR, Chang B, Cai X, Pasula S, Kwak S, Yang W, Bischoff J, Xu J, Bielenberg DR, Dixon JB, D'Amato RJ, Srinivasan RS, Chen H. Epsin deficiency promotes lymphangiogenesis through regulation of VEGFR3 degradation in diabetes. Journal of Clinical Investigation. 2018 Aug 31;128(9):4025-4043.

Zhu Y, Dean AE, Horikoshi N, Heer C, Spitz DR, Gius D. Emerging evidence for targeting mitochondrial metabolic dysfunction in cancer therapy. Journal of Clinical Investigation. 2018 Aug 31;128(9):3682-3691.

Chen FX, Smith ER, Shilatifard A. Born to run: control of transcription elongation by RNA polymerase II. Nature Reviews Molecular Cell Biology. 2018 Jul;19(7):464-478.

Cortes J, Perl AE, Dohner H, Kantarjian H, Martinelli G, Kovacsovics T, Rousselot P, Steffen B, Dombret H, Estey E, Strickland S, Altman JK, Baldus CD, Burnett A, Kramer A, Russell N, Shah NP, Smith CC, Wang ES, Ifrah N, Gammon G, Trone D, Lazzaretto D, Levis M. Quizartinib, an FLT3 inhibitor, as monotherapy in patients with relapsed or refractory acute myeloid leukaemia: an open-label, multicentre, single-arm, phase 2 trial. Lancet Oncology. 2018 Jul;19(7):889-903.

Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Davidson K, Doubeni CA, Epling J, Kemper AR, Kubik M, Landefeld CS, Mangione CM, Silverstein M, Simon MA, Tseng CW, Wong JB, Force USPST. Screening for Peripheral Artery Disease and Cardiovascular Disease Risk Assessment With the Ankle-Brachial Index US Preventive Services Task Force Recommendation Statement. JAMA. 2018 Jul;320(2):177-183.

Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Davidson K, Doubeni CA, Epling JW, Kemper AR, Kubik M, Landefeld S, Mangione CM, Silverstein M, Simon MA, Tseng CW, Wong JB, Force USPST. Risk Assessment for Cardiovascular Disease With Nontraditional Risk Factors US Preventive Services Task Force Recommendation Statement. JAMA. 2018 Jul;320(3):272-280.

Evans IVR, Phillips GS, Alpern ER, Angus DC, Friedrich ME, Kissoon N, Lemeshow S, Levy MM, Parker MM, Terry KM, Watson RS, Weiss SL, Zimmerman J, Seymour CW. Association Between the New York Sepsis Care Mandate and In-Hospital Mortality for Pediatric Sepsis. JAMA. 2018 Jul;320(4):358-367.

Friedman SL, Neuschwander-Tetri BA, Rinella M, Sanyal AJ. Mechanisms of NAFLD development and therapeutic strategies. Nature Medicine. 2018 Jul;24(7):908-922.

Hsiao HM, Fernandez R, Tanaka S, Li WJ, Spahn JH, Chiu S,Akbarpour M, Ruiz-Perez D, Wu Q, Turam C, Scozzi D, Takahashi T, Luehmann HP, Puri V, Budinger GRS, Krupnick AS, Misharin AV, Lavine KJ, Liu YJ, Gelman AE, Bharat A, Kreisel D. Spleen-derived classical monocytes mediate lung ischemia-reperfusion injury through IL-beta. Journal of Clinical Investigation. 2018 Jul;128(7):2833-2847.

Jaroentomeechai T, Stark JC, Natarajan A, Glasscock CJ, Yates LE, Hsu KJ, Mrksich M, Jewett MC, DeLisa MP. Single-pot glycoprotein biosynthesis using a cell-free transcription-translation system enriched with glycosylation machinery. Nature Communications. 2018 Jul;9:11.

Sato T, Chang HC, Bayeva M, Shapiro JS, Ramos-Alonso L, Kouzu H, Jiang XH, Liu T, Yar S, Sawicki KT, Chen CL, Martinez-Pastor MT, Stumpo DJ, Schumacker PT, Blackshear PJ, Ben-Sahra I, Puig S, Ardehali H. mRNA-binding protein tristetraprolin is essential for cardiac response to iron deficiency by regulating mitochondrial function. Proceedings of the National Academy of Sciences of the United States of America. 2018 Jul;115(27):E6291-E6300.

Sparano JA, Gray RJ, Makower DF, Pritchard KI, Albain KS, Hayes DF, Geyer CE, Dees EC, Goetz MP, Olson JA, Lively T, Badve SS, Saphner TJ, Wagner LI, Whelan TJ, Ellis MJ, Paik S, Wood WC, Ravdin PM, Keane MM, Moreno HLG, Reddy PS, Goggins TF, Mayer IA, Brufsky AM, Toppmeyer DL, Kaklamani VG, Berenberg JL, Abrams J, Sledge GW. Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer. New England Journal of Medicine. 2018 Jul;379(2):111-121.

Sun L, Lin HX, Kohlstedt KL, Schatz GC, Mirkin CA. Design principles for photonic crystals based on plasmonic nanoparticle superlattices. Proceedings of the National Academy of Sciences of the United States of America. 2018 Jul;115(28):7242-7247.

Wyss AB, Sofer T, Lee MK, et al. (including Kalhan R). Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function. Nature Communications. 2018 Jul;9:15.

Chin SM, Synatschke CV, Liu SP, Nap RJ, Sather NA, Wang QF, Alvarez Z, Edelbrock AN, Fyrner T, Palmer LC, Szleifer I, de la Cruz MO, Stupp SI. Covalent-supramolecular hybrid polymers as muscle-inspired anisotropic actuators. Nature Communications. 2018 Jun;9:11.

Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Davidson K, Doubeni CA, Epling JW, Kemper AR, Kubik M, Landefeld CS, Mangione CM, Silverstein M, Simon MA, Tseng CW, Wong JB, Force USPST. Screening for Cardiovascular Disease Risk With Electrocardiography US Preventive Services Task Force Recommendation Statement. JAMA. 2018 Jun;319(22):2308-2314.

Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Davidson KW, Doubeni CA, Epling JW, Kemper AR, Kubik M, Landefeld S, Mangione CM, Phipps MG, Pignone M, Silverstein M, Simon MA, Tseng CW, Wong JB, Force USPST. Screening for Osteoporosis to Prevent Fractures US Preventive Services Task Force Recommendation Statement. JAMA. 2018 Jun;319(24):2521-2531.

Dhar SS, Zhao DY, Lin T, Gu BN, Pal K, Wu SJ, Alam H, Lv J, Yun K, Gopalakrishnan V, Flores ER, Northcott PA, Rajaram V, Li W, Shilatifard A, Sillitoe RV, Chen KF, Lee MG. MLL4 Is Required to Maintain Broad H3K4me3 Peaks and Super-Enhancers at Tumor Suppressor Genes. Molecular Cell. 2018 Jun;70(5):825.

DiNardo CD, Stein EM, de Botton S, Roboz GJ, Altman JK, Mims AS, Swords R, Collins RH, Mannis GN, Pollyea DA, Donnellan W, Fathi AT, Pigneux A, Erba HP, Prince GT, Stein AS, Uy GL, Foran JM, Traer E, Stuart RK, Arellano ML, Slack JL, Sekeres MA, Willekens C, Choe S, Wang H, Zhang V, Yen KE, Kapsalis SM, Yang H, Dai D, Fan B, Goldwasser M, Liu H, Agresta S, Wu B, Attar EC, Tallman MS, Stone RM, Kantarjian HM. Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML. New England Journal of Medicine. 2018 Jun;378(25):2386-2398.

Dix DB, Seibel NL, Chi YY, Khanna G, Gratias E, Anderson JR, Mullen EA, Geller JI, Kalapurakal JA, Paulino AC, Perlman EJ, Ehrlich PF, Malogolowkin M, Gastier-Foster JM, Wagner E, Grundy PE, Fernandez CV, Dome JS. Treatment of Stage IV Favorable Histology Wilms Tumor With Lung Metastases: A Report From the Children's Oncology Group AREN0533 Study. Journal of Clinical Oncology. 2018 Jun;36(16):1564.

Edamakanti CR, Do J, Didonna A, Martina M, Opal P. Mutant ataxin1 disrupts cerebellar development in spinocerebellar ataxia type 1. Journal of Clinical Investigation. 2018 Jun;128(6):2252-2265.

Fullman N, Yearwood J, Abay SM, et al (including Yano Y). Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden of Disease Study 2016. Lancet. 2018 Jun;391(10136):2236-2271.

Gonen N, Futtner CR, Wood S, Garcia-Moreno SA, Salamone IM, Samson SC, Sekido R, Poulat F, Maatouk DM, Lovell-Badge R. Sex reversal following deletion of a single distal enhancer of Sox9. Science. 2018 Jun 29;360(6396):1469-1473.

Guzman JN, Ilijic E, Yang B, Sanchez-Padilla J, Wokosin D, Galtieri D, Kondapalli J, Schumacker PT, Surmeier DJ. Systemic isradipine treatment diminishes calcium-dependent mitochondrial oxidant stress. Journal of Clinical Investigation. 2018 Jun;128(6):2266-2280.

Hussain M, Fizazi K, Saad F, Rathenborg P, Shore N, Ferreira U, Ivashchenko P, Demirhan E, Modelska K, Phung, Krivoshik A, Sternberg CN. Enzalutamide in Men with Nonmetastatic, Castration-Resistant Prostate Cancer. New England Journal of Medicine. 2018 Jun 28;378(26):2465-2474.

Jayaraj ND, Bhattacharyya BJ, Belmadani AA, Ren DJ, Rathwell CA, Hackelberg S, Hopkins BE, Gupta HR, Miller RJ, Menichella DM. Reducing CXCR4-mediated nociceptor hyperexcitability reverses painful diabetic neuropathy.Journal of Clinical Investigation. 2018 Jun;128(6):2205-2225.

Kightlinger W, Lin L, Rosztoczy M, Li WH, DeLisa MP, Mrksich M, Jewett MC. Design of glycosylation sites by rapid synthesis and analysis of glycosyltransferases. Nature Chemical Biology. 2018 Jun;14(6):627.

Kuppermann N, Ghetti S, Schunk JE, Stoner MJ, Rewers A, McManemy JK, Myers SR, Nigrovic LE, Garro A, Brown KM, Quayle KS, Trainor JL, Tzimenatos L, Bennett JE, DePiero AD, Kwok MY, Perry CS, Olsen CS, Casper TC, Dean JM, Glaser NS, Grp PDFS. Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis. New England Journal of Medicine. 2018 Jun;378(24):2275-2287.

Mannix AJ, Zhang ZH, Guisinger NP, Yakobson BI, Hersam MC. Borophene as a prototype for synthetic 2D materials development.Nature Nanotechnology. 2018 Jun;13(6):444-450.

Patriarchi T, Cho JR, Merten K, Howe MW, Marley A, Xiong WH, Folk RW, Broussard GJ, Liang R, Jang MJ, Zhong H, Dombeck D, von Zastrow M, Nimmerjahn A, Gradinaru V, Williams JT, Tian L. Ultrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors. Science. 2018 Jun 29;360(6396).

Pottier C, Zhou XL, Perkerson RB, et al. (including Grafman J, Mesulam MM, Weintraub S, Bigio EH). Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. Lancet Neurology. 2018 Jun;17(6):548-558.

Shanks GW, Tester DJ, Ackerman JP, Simpson MA, Behr ER, White SM, Ackerman MJ. Importance of Variant Interpretation in Whole-Exome Molecular Autopsy Population-Based Case Series. Circulation. 2018 Jun;137(25):2705-2715.

Srivastava S, Zasadzinska E, Foltz DR. Posttranslational mechanisms controlling centromere function and assembly. Current Opinion in Cell Biology. 2018 Jun;52:126-135.

Wang G, Biswas AK, Ma WC, Kandpal M, Coker C, Grandgenett PM, Hollingsworth MA, Jain R, Tanji K, Lopez-Pintado S, Borczuk A, Hebert D, Jenkitkasemwong S, Hojyo S, Davuluri RV, Knutson MD, Fukada T, Acharyya S. Metastatic cancers promote cachexia through ZIP14 upregulation in skeletal muscle.Nature Medicine. 2018 Jun;24(6):770.

Wang L, Zhao Z, Ozark PA, Fantini D, Marshall SA, Rendleman EJ, Cozzolino KA, Louis N, He X, Morgan MA, Takahashi YH, Collings CK, Smith ER, Ntziachristos P, Savas JN, Zou L, Hashizume R, Meeks JJ, Shilatifard A.Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy. Nature Medicine. 2018 Jun;24(6):758-769.

Xu L, Gordon R, Farmer R, Pattanayak A, Binkowski A, Huang XK, Avram M, Krishna S, Voll E, Payese J, Chavez J, Bruce J, Mazar A, Nibbs A, Anderson W, Li L, Jovanovic B, Pruell S, Valsecchi M, Francia G, Betori R, Scheidt K, Bergan R. Precision therapeutic targeting of human cancer cell motility. Nature Communications. 2018 Jun;9:14.

Zhang X, Xue CY, Line J, Ferguson JF, Weiner A, Liu W, Han YM, Hinkley C, Li WJ, Jiang HF, Gosai S, Hachet M, Garcia BA, Gregory BD, Soccio RE, Hogeneschl JB, Seale P, Li MY, Reilly MP. Interrogation of nonconserved human adipose lincRNAs identifies a regulatory role of linc-ADAL in adipocyte metabolism. Science Translational Medicine. 2018 Jun;10(446):16.

Zhu YX, Cankova Z, Iwanaszko M, Lichtor S, Mrksich M, Ameer GA. Potent laminin-inspired antioxidant regenerative dressing accelerates wound healing in diabetes. Proceedings of the National Academy of Sciences of the United States of America. 2018 Jun;115(26):6816-6821.

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Gore L, Kearns PR, de Martino ML, Lee, De Souza CA, Bertrand Y, Hijiya N, Stork LC, Chung NG, Cardos RC, Saikia T, Fagioli F, Seo JJ, Landman-Parker J, Lancaster D, Place AE, Rabin KR, Sacchi M, Swanink R, Zwaan CM. Dasatinib in Pediatric Patients With Chronic Myeloid Leukemia in Chronic Phase: Results From a Phase II Trial. Journal of Clinical Oncology. 2018 May 1;36(13):1330-1338.

Grossman DC, Curry SJ, Owens DK, Bibbins-Domingo K, Caughey AB, Davidson KW, Doubeni CA, Ebel M, Epling JW, Kemper AR, Krist AH, Kubik M, Landefeld CS, Mangione CM, Silverstein M, Simon MA, Siu AL, Tseng CW, Force USPST. Screening for Prostate Cancer US Preventive Services Task Force Recommendation Statement.JAMA. 2018 May;319(18):1901-1913.

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Indra I, Choi J, Chen CS, Troyanovsky RB, Shapiro L, Honig B, Troyanovsky SM.Spatial and temporal organization of cadherin in punctate adherens junctions. Proceedings of the National Academy of Sciences of the United States of America. 2018 May;115(19):E4406-E4415.

Ji Z, He LZ, Rotem A, Janzer A, Cheng CS, Regev A, Struhl K. Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation. Nature Communications. 2018 May;9.

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Ma BBY, Lim WT, Goh BC, Hui EP, Lo KW, Pettinger A, Foster NR, Riess JW, Agulnik M, Chang AYC, Chopra A, Kish JA, Chung CH, Adkins DR, Cullen KJ, Gitlitz BJ, Lim DW, To KF, Chan KCA, Lo YMD, King AD, Erlichman C, Yin J, Costello BA, Chan ATC. Antitumor Activity of Nivolumab in Recurrent and Metastatic Nasopharyngeal Carcinoma: An International, Multicenter Study of the Mayo Clinic Phase 2 Consortium (NCI-9742).Journal of Clinical Oncology. 2018 May;36(14):1412.

Martin MP, Naranbhai V, Shea PR, Qi Y, Ramsuran V, Vince N, Gao XJ, Thomas R, Brumme ZL, Carlson JM, Wolinsky SM, Goedert JJ, Walker BD, Segal FP, Deeks SG, Haas DW, Migueles SA, Connors M, Michael N, Fellay J, Gostick E, Llewellyn-Lacey S, Price DA, Lafont BA, Pymm P, Saunders PM, Widjaja J, Wong SC, Vivian JP, Rossjohn J, Brooks AG, Carrington M. Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1. Journal of Clinical Investigation. 2018 May;128(5):1903-1912.

Nguyen M, Krainc D. LRRK2 phosphorylation of auxilin mediates synaptic defects in dopaminergic neurons from patients with Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 2018 May;115(21):5576-5581.

Nguyen QH, Pervolarakis N, Blake K, Ma D, Davis RT, James N, Phung AT, Willey E, Kumar R, Jabart E, Driver I, Rock J, Goga A, Khan SA, Lawson DA, Werb Z, Kessenbrock K. Profiling human breast epithelial cells using single cell RNA sequencing identifies cell diversity. Nature Communications. 2018 May;9.

North JP, Golovato J, Vaske CJ, Sanborn JZ, Nguyen A, Wu W, Goode B, Stevers M, McMullen K, White BEP, Collisson EA, Bloomer M, Solomon DA, Benz SC, Cho RJ. Cell of origin and mutation pattern define three clinically distinct classes of sebaceous carcinoma. Nature Communications. 2018 May;9.

Yang H, Wang W, Romano KA, Gu M, Sanidad KZ, Kim D, Yang J, Schmidt B, Panigrahy D, Pei R, Martin DA, Ozay EI, Wang Y, Song M, Bolling BW, Xiao H, Minter LM, Yang GY, Liu Z, Rey FE, Zhang G. A common antimicrobial additive increases colonic inflammation and colitis-associated colon tumorigenesis in mice. Science Translational Medicine. 2018 May 30;10(443).

Yeung PSW, Yamashita M, Ing CE, Pomes R, Freymann DM, Prakriya M. Mapping the functional anatomy of Orai1 transmembrane domains for CRAC channel gating. Proceedings of the National Academy of Sciences of the United States of America. 2018 May;115(22):E5193-E5202.

Yun S, Reynolds RP, Petrof I, White A, Rivera PD, Segev A, Gibson AD, Suarez M, DeSalle MJ, Ito N, Mukherjee S, Richardson DR, Kang CE, Ahrens-Nicklas RC, Soler I, Chetkovich DM, Kourrich S, Coulter DA, Eisch AJ. Stimulation of entorhinal cortex-dentate gyrus circuitry is antidepressive. Nature Medicine. 2018 May;24(5):658.

Zhao JJ, Lupino K, Wilkins BJ, Qiu CX, Liu J, Omura Y, Allred AL, McDonald C, Susztak K, Barish GD, Pei LM. Genomic integration of ERR gamma-HNF1 beta regulates renal bioenergetics and prevents chronic kidney disease. Proceedings of the National Academy of Sciences of the United States of America. 2018 May;115(21):E4910-E4919.

Anker JF, Naseem AF, Mok H, Schaeffer AJ, Abdulkadir SA, Thumbikat P.Multi-faceted immunomodulatory and tissue-tropic clinical bacterial isolate potentiates prostate cancer immunotherapy. Nature Communications. 2018 Apr;9:14.

Chaiyachati KH, Bhatt J, Zhu JM. Time for Value-Based Payment Models to Adopt a Disparities-Sensitive Frame Shift.Annals of Internal Medicine. 2018 Apr 3;168(7):509-510.

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Chen X, Park YJ, Kang M, Kang SK, Koo J, Shinde SM, Shin J, Jeon S, Park G, Yan Y, MacEwan MR, Ray WZ, Lee KM, Rogers JA, Ahn JH. CVD-grown monolayer MoS2 in bioabsorbable electronics and biosensors. Nature Communications. 2018 Apr;9:12.

Desai SV, Asch DA, Bellini LM, Chaiyachati KH, Liu M, Sternberg AL, Tonascia J, Yeager AM, Asch JM, Katz JT, Basner M, Bates DW, Bilimoria KY, Dinges DF, Even-Shoshan O, Shade DM, Silber JH, Small DS, Volpp KG, Shea JA, i CRG. Education Outcomes in a Duty-Hour Flexibility Trial in Internal Medicine.New England Journal of Medicine. 2018 Apr;378(16):1494-1508.

Fadelu T, Zhang S, Niedzwiecki D, Ye X, Saltz LB, Mayer RJ, Mowat RB, Whittom R, Hantel A, Benson A, Atienza DM, Messino M, Kindler HL, Venook A, Ogino S, Ng K, Wu K, Willett W, Giovannucci E, Meyerhardt J, Bao Y, Fuchs CS. Nut Consumption and Survival in Patients With Stage III Colon Cancer: Results From CALGB 89803 (Alliance). Journal of Clinical Oncology. 2018 Apr;36(11):1112.

Forrest MP, Parnell E, Penzes P. Dendritic structural plasticity and neuropsychiatric disease. Nature Reviews Neuroscience. 2018 Apr;19(4):215-234.

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Grossman DC, Curry SJ, Owens DK, Barry M, Caughey AB, Davidson KW, Doubeni CA, Epling JW, Kemper AR, Krist AH, Kubik M, Landefeld S, Mangione CM, Pignone M, Silverstein M, Simon MA, Tseng CW, Force USPST. Interventions to Prevent Falls in Community-Dwelling Older Adults US Preventive Services Task Force Recommendation Statement. JAMA-Journal of the American Medical Association. 2018 Apr;319(16):1696-1704.

Grossman DC, Curry SJ, Owens DK, Barry MJ, Caughey AB, Davidson KW, Doubeni CA, Epling JW, Kemper AR, Krist AH, Kubik M, Landefeld S, Mangione CM, Silverstein M, Simon MA, Tseng CW, Force USPST. Vitamin D, Calcium, or Combined Supplementation for the Primary Prevention of Fractures in Community-Dwelling Adults US Preventive Services Task Force Recommendation Statement. JAMA-Journal of the American Medical Association. 2018 Apr;319(15):1592-1599.

Han S, Kim J, Won SM, Ma YJ, Kang D, Xie ZQ, Lee KT, Chung HU, Banks A, Min S, Heo SY, Davies CR, Lee JW, Lee CH, Kim BH, Li K, Zhou YD, Wei C, Feng X, Huang YG, Rogers JA. Battery-free, wireless sensors for full-body pressure and temperature mapping.Science Translational Medicine. 2018 Apr;10(435):13.

Howard JD, Kahnt T.Identity prediction errors in the human midbrain update reward-identity expectations in the orbitofrontal cortex. Nature Communications. 2018 Apr;9:11.

Huang LL, Chen PC, Liu M, Fu XB, Gordiichuk P, Yu YN, Wolverton C, Kang YJ, Mirkin CA. Catalyst design by scanning probe block copolymer lithography. Proceedings of the National Academy of Sciences of the United States of America. 2018 Apr;115(15):3764-3769.

Hussain M, Daignault-Newton S, Twardowski PW, Albany C, Stein MN, Kunju LP, Siddiqui J, Wu YM, Robinson D, Lonigro RJ, Cao X, Tomlins SA, Mehra R, Cooney KA, Montgomery B, Antonarakis ES, Shevrin DH, Corn PG, Whang YE, Smith DC, Caram MV, Knudsen KE, Stadler WM, Feng FY, Chinnaiyan AM. Targeting Androgen Receptor and DNA Repair in Metastatic Castration-Resistant Prostate Cancer: Results From NCI 9012. Journal of Clinical Oncology. 2018 Apr 1;36(10):991-999.

Kyriakopoulos CE, Chen YH, Carducci MA, Liu G, Jarrard DF, Hahn NM, Shevrin DH, Dreicer R, Hussain M, Eisenberger M, Kohli M, Plimack ER, Vogelzang NJ, Picus J, Cooney MM, Garcia JA, DiPaola RS, Sweeney CJ. Chemohormonal Therapy in Metastatic Hormone-Sensitive Prostate Cancer: Long-Term Survival Analysis of the Randomized Phase III E3805 CHAARTED Trial. Journal of Clinical Oncology. 2018 Apr;36(11):1080.

Lee W, Liu Y, Lee Y, Sharma BK, Shinde SM, Kim SD, Nan K, Yan Z, Han MD, Huang YG, Zhang YH, Ahn JH, Rogers JA. Two-dimensional materials in functional three-dimensional architectures with applications in photodetection and imaging. Nature Communications. 2018 Apr;9:9.

Li H, Zhang BH, Lu XG, Tan XY, Jia F, Xiao Y, Cheng ZH, Li Y, Silva DO, Schrekker HS, Zhang K, Mirkin CA. Molecular spherical nucleic acids. Proceedings of the National Academy of Sciences of the United States of America. 2018 Apr;115(17):4340-4344.

Lozoya OA, Martinez-Reyes I, Wang T, Grenet D, Bushel P, Li J, Chandel N, Woychik RP, Santos JH. Mitochondrial nicotinamide adenine dinucleotide reduced (NADH) oxidation links the tricarboxylic acid (TCA) cycle with methionine metabolism and nuclear DNA methylation. PLoS Biology. 2018 Apr;16(4):e2005707.

McDermott MM, Spring B, Berger JS, Treat-Jacobson D, Conte MS, Creager MA, Criqui MH, Ferrucci L, Gornik HL, Guralnik JM, Hahn EA, Henke P, Kibbe MR, Kohlman-Trighoff D, Li LY, Lloyd-Jones D, McCarthy W, Polonsky TS, Skelly C, Tian L, Zhao LH, Zhang DX, Rejeski J. Effect of a Home-Based Exercise Intervention of Wearable Technology and Telephone Coaching on Walking Performance in Peripheral Artery Disease The HONOR Randomized Clinical Trial. JAMA-Journal of the American Medical Association. 2018 Apr;319(16):1665-1676.

Mokdad AH, Ballestros K, Echko M, et al. (including Yano Y). The State of US Health, 1990-2016 Burden of Diseases, Injuries, and Risk Factors Among US States. JAMA-Journal of the American Medical Association. 2018 Apr;319(14):1444-1472.

Morgans AK, Chen YH, Sweeney CJ, Jarrard DF, Plimack ER, Gartrell BA, Carducci MA, Hussain M, Garcia JA, Cella D, DiPaola RS, Patrick-Miller LJ. Quality of Life During Treatment With Chemohormonal Therapy: Analysis of E3805 Chemohormonal Androgen Ablation Randomized Trial in Prostate Cancer. Journal of Clinical Oncology. 2018 Apr;36(11):1088.

Ntai I, Fornelli L, DeHart CJ, Hutton JE, Doubleday PF, Leduc RD, van Nispen AJ, Fellers RT, Whiteley G, Boja ES, Rodriguez H, Kelleher NL. Precise characterization of KRAS4b proteoforms in human colorectal cells and tumors reveals mutation/modification cross-talk. Proceedings of the National Academy of Sciences of the United States of America. 2018 Apr;115(16):4140-4145.

Pandey A, Omar W, Ayers C, LaMonte M, Klein L, Allen NB, Kuller LH, Greenland P, Eaton CB, Gottdiener JS, Lloyd-Jones DM, Berry JD. Sex and Race Differences in Lifetime Risk of Heart Failure With Preserved Ejection Fraction and Heart Failure With Reduced Ejection Fraction. Circulation. 2018 Apr;137(17):1814.

Pool LR, Burgard SA, Needham BL, Elliott MR, Langa KM, de Leon CFM. Association of a Negative Wealth Shock With All-Cause Mortality in Middle-aged and Older Adults in the United States. JAMA-Journal of the American Medical Association. 2018 Apr;319(13):1341-1350.

Procter DJ, Banerjee A, Nukui M, Kruse K, Gaponenko V, Murphy EA, Komarova Y, Walsh D. The HCMV Assembly Compartment Is a Dynamic Golgi-Derived MTOC that Controls Nuclear Rotation and Virus Spread. Developmental Cell. 2018 Apr;45(1):83.

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Chai S, Wan X, Ramirez-Navarro A, Tesar PJ, Kaufman ES, Ficker E, George AL, Jr., Deschenes I. Physiological genomics identifies genetic modifiers of long QT syndrome type 2 severity. Journal of Clinical Investigation. 2018 Mar 1;128(3):1043-1056.

Chu LH, Indramohan M, Ratsimandresy RA, Gangopadhyay A, Morris EP, Monack DM, Dorfleutner A, Stehlik C.The oxidized phospholipid oxPAPC protects from septic shock by targeting the non-canonical inflammasome in macrophages. Nature Communications. 2018 Mar;9:16.

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Grossman DC, Curry SJ, Owens DK, Barry MJ, Caughey AB, Davidson KW, Doubeni CA, Epling JW, Kemper AR, Krist AH, Kubik M, Landefeld S, Mangione CM, Silverstein M, Simon MA, Tseng CW, Force USPST. Behavioral Counseling to Prevent Skin Cancer US Preventive Services Task Force Recommendation Statement. JAMA. 2018 Mar;319(11):1134-1142.

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Johnston SRD, Hegg R, Im SA, Park IH, Burdaeva O, Kurteva G, Press MF, Tjulandin S, Iwata H, Simon SD, Kenny S, Sarp S, Izquierdo MA, Williams LS, Gradishar WJ. Phase III, Randomized Study of Dual Human Epidermal Growth Factor Receptor 2 (HER2) Blockade With Lapatinib Plus Trastuzumab in Combination With an Aromatase Inhibitor in Postmenopausal Women With HER2-Positive, Hormone Receptor-Positive Metastatic Breast Cancer: ALTERNATIVE. Journal of Clinical Oncology. 2018 Mar;36(8):741.

Karmali KN, Lloyd-Jones DM, van der Leeuw J, Goff DC, Jr., Yusuf S, Zanchetti A, Glasziou P, Jackson R, Woodward M, Rodgers A, Neal BC, Berge E, Teo K, Davis BR, Chalmers J, Pepine C, Rahimi K, Sundstrom J. Blood pressure-lowering treatment strategies based on cardiovascular risk versus blood pressure: A meta-analysis of individual participant data. PLoS Medicine. 2018 Mar;15(3):e1002538.

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Kim Y, Bravo E, Thirnbeck CK, Smith-Mellecker LA, Kim SH, Gehlbach BK, Laux LC, Zhou X, Nordli DR, Jr., Richerson GB. Severe peri-ictal respiratory dysfunction is common in Dravet syndrome. Journal of Clinical Investigation. 2018 Mar 1;128(3):1141-1153.

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Martin RW, Des Soye BJ, Kwon YC, Kay J, Davis RG, Thomas PM, Majewska NI, Chen CX, Marcum RD, Weiss MG, Stoddart AE, Amiram M, Charna AKR, Patel JR, Isaacs FJ, Kelleher NL, Hong SH, Jewett MC. Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids. Nature Communications. 2018 Mar;9:9.

McQuade JL, Daniel CR, Hess KR, et al. (including Sosman JA). Association of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysis. Lancet Oncology. 2018 Mar;19(3):310-322. 

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Brown PD, Ahluwalia MS, Khan OH, Asher AL, Wefel JS, Gondi V. Whole-Brain Radiotherapy for Brain Metastases: Evolution or Revolution? Journal of Clinical Oncology. 2018 Feb;36(5):483.

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Goode B, Mondal G, Hyun M, Ruiz DG, Lin YH, Van Ziffle J, Joseph NM, Onodera C, Talevich E, Grenert JP, Hewedi IH, Snuderl M, Brat DJ, Kleinschmidt-DeMasters BK, Rodriguez FJ, Louis DN, Yong WH, Lopes MB, Rosenblum MK, Butowski N, Tihan T, Bollen AW, Phillips JJ, Wiita AP, Yeh I, Jacobson MP, Bastian BC, Perry A, Solomon DA. A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle. Nature Communications. 2018 Feb;9:8.

Grossman DC, Curry SJ, Owens DK, Barry MJ, Davidson KW, Doubeni CA, Epling JW, Kemper AR, Krist AH, Kurth AE, Landefeld S, Mangione CM, Phipps MG, Silverstein M, Simon MA, Tseng CW, Force USPST. Screening for Ovarian Cancer US Preventive Services Task Force Recommendation Statement. JAMA. 2018 Feb;319(6):588-594.

Harshman LC, Chen YH, Liu G, Carducci MA, Jarrard D, Dreicer R, Hahn N, Garcia JA, Hussain M, Shevrin D, Eisenberger M, Kohli M, Plimack ER, Cooney M, Vogelzang NJ, Picus J, Dipaola R, Sweeney CJ. Seven-Month Prostate-Specific Antigen Is Prognostic in Metastatic Hormone-Sensitive Prostate Cancer Treated With Androgen Deprivation With or Without Docetaxel. Journal of Clinical Oncology. 2018 Feb 1;36(4):376-382.

Huffman MD, Mohanan PP, Devarajan R, Baldridge AS, Kondal D, Zhao LH, Ali M, Krishnan MN, Natesan S, Gopinath R, Viswanathan S, Stigi J, Joseph J, Chozhakkat S, Lloyd-Jones DM, Prabhakaran D, Acute Coronary Syndrome Q. Effect of a Quality Improvement Intervention on Clinical Outcomes in Patients in India With Acute Myocardial Infarction The ACS QUIK Randomized Clinical Trial. JAMA. 2018 Feb;319(6):567-578.

Karabin NB, Allen S, Kwon HK, Bobbala S, Firlar E, Shokuhfar T, Shull KR, Scott EA. Sustained micellar delivery via inducible transitions in nanostructure morphology. Nature Communications. 2018 Feb;9:13.

Laiteerapong N, Cooper JM, Skandari MR, Clarke PM, Winn AN, Naylor RN, Huang ES. Individualized Glycemic Control for U. S. Adults With Type 2 Diabetes A Cost-Effectiveness Analysis. Annals of Internal Medicine. 2018 Feb;168(3):170.

Larkin J, Minor D, D'Angelo S, Neyns B, Smylie M, Miller WH, Jr., Gutzmer R, Linette G, Chmielowski B, Lao CD, Lorigan P, Grossmann K, Hassel JC, Sznol M, Daud A, Sosman J, Khushalani N, Schadendorf D, Hoeller C, Walker D, Kong G, Horak C, Weber J. Overall Survival in Patients With Advanced Melanoma Who Received Nivolumab Versus Investigator's Choice Chemotherapy in CheckMate 037: A Randomized, Controlled, Open-Label Phase III Trial. Journal of Clinical Oncology. 2018 Feb 1;36(4):383-390.

Li R, Guiney LM, Chang CH, Mansukhani ND, Ji Z, Wang X, Liao YP, Jiang W, Sun B, Hersam MC, Nel AE, Xia T. Surface Oxidation of Graphene Oxide Determines Membrane Damage, Lipid Peroxidation, and Cytotoxicity in Macrophages in a Pulmonary Toxicity Model. ACS Nano. 2018 Feb 27;12(2):1390-1402.

Lin QY, Mason JA, Li ZY, Zhou WJ, O'Brien MN, Brown KA, Jones MR, Butun S, Lee B, Dravid VP, Aydin K, Mirkin CA. Building superlattices from individual nanoparticles via template-confined DNA-mediated assembly. Science. 2018 Feb;359(6376):669-672.

Linehan JL, Harrison OJ, Han SJ, Byrd AL, Vujkovic-Cvijin I, Villarino AV, Sen SK, Shaik J, Smelkinson M, Tamoutounour S, Collins N, Bouladoux N, Dzutsev A, Rosshart SP, Arbuckle JH, Wang CR, Kristie TM, Rehermann B, Trinchieri G, Brenchley JM, O'Shea JJ, Belkaid Y. Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair. Cell. 2018 Feb;172(4):784.

Lu LY, Gutruf P, Xia L, Bhatti DL, Wang XY, Vazquez-Guardado A, Ning X, Shen XR, Sang T, Ma RX, Pakeltis G, Sobczak G, Zhang H, Seo DO, Xue MT, Yin L, Chanda D, Sheng X, Bruchas MR, Rogers JA. Wireless optoelectronic photometers for monitoring neuronal dynamics in the deep brain. Proceedings of the National Academy of Sciences of the United States of America. 2018 Feb;115(7):E1374-E1383.

Morgans AK. Optimization of Risk Stratification in Localized Prostate Cancer. Journal of Clinical Oncology. 2018 Feb;36(6):528.

Moriguchi S, Ishizuka T, Yabuki Y, Shioda N, Sasaki Y, Tagashira H, Yawo H, Yeh JZ, Sakagami H, Narahashi T, Fukunaga K. Blockade of the K-ATP channel Kir6.2 by memantine represents a novel mechanism relevant to Alzheimer's disease therapy. Molecular Psychiatry. 2018 Feb;23(2):211-221.

Radvansky BA, Dombeck DA. An olfactory virtual reality system for mice. Nature Communications. 2018 Feb 26;9(1):839.

Russi AE, Ebel ME, Yang YC, Brown MA. Male-specific IL-33 expression regulates sex-dimorphic EAE susceptibility. Proceedings of the National Academy of Sciences of the United States of America. 2018 Feb;115(7):E1520-E1529.

Saadalla AM, Osman A, Gurish MF, Dennis KL, Blatner NR, Pezeshki A, McNagny KM, Cheroutre H, Gounari F, Khazaie K. Mast cells promote small bowel cancer in a tumor stage-specific and cytokine-dependent manner. Proceedings of the National Academy of Sciences of the United States of America. 2018 Feb;115(7):1588-1592.

Sangwan VK, Lee HS, Bergeron H, Balla I, Beck ME, Chen KS, Hersam MC. Multi-terminal memtransistors from polycrystalline monolayer molybdenum disulfide. Nature. 2018 Feb;554(7693):500.

Souma T, Thomson BR, Heinen S, Carota IA, Yamaguchi S, Onay T, Liu P, Ghosh AK, Li CJ, Eremina V, Hong YK, Economides AN, Vestweber D, Peters KG, Jin J, Quaggin SE. Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP. Proceedings of the National Academy of Sciences of the United States of America. 2018 Feb;115(6):1298-1303.

Spratt DE, Zhang JB, Santiago-Jimenez M, Dess RT, Davis JW, Den RB, Dicker AP, Kane CJ, Pollack A, Stoyanova R, Abdollah F, Ross AE, Cole A, Uchio E, Randall JM, Nguyen H, Zhao SG, Mehra R, Glass AG, Lam LLC, Chelliserry J, du Plessis M, Choeurng V, Aranes M, Kolisnik T, Margrave J, Alter J, Jordan J, Buerki C, Yousefi K, Haddad Z, Davicioni E, Trabulsi EJ, Loeb S, Tewari A, Carroll PR, Weinmann S, Schaeffer EM, Klein EA, Karnes RJ, Feng FY, Nguyen PL. Development and Validation of a Novel Integrated Clinical-Genomic Risk Group Classification for Localized Prostate Cancer. Journal of Clinical Oncology. 2018 Feb;36(6):581.

Thiagarajan PS, Sinyuk M, Turaga SM, Mulkearns-Hubert EE, Hale JS, Rao V, Demelash A, Saygin C, China A, Alban TJ, Hitomi M, Torre-Healy LA, Alvarado AG, Jarrar A, Wiechert A, Adorno-CruzV, Fox PL, Calhoun BC, Guan JL, Liu HP, Reizes O, Lathia JD. Cx26 drives self-renewal in triple-negative breast cancer via interaction with NANOG and focal adhesion kinase. Nature Communications. 2018 Feb;9:14.

Vaccarino V, Sullivan S, Hammadah M, Wilmot K, Al Mheid I, Ramadan R, Elon L, Pimple PM, Garcia EV, Nye J, Shah AJ, Alkhoder A, Levantsevych O, Gay H, Obideen M, Huang MX, Lewis TT, Bremner JD, Quyyumi AA, Raggi P. Mental Stress-Induced-Myocardial Ischemia in Young Patients With Recent Myocardial Infarction Sex Differences and Mechanisms. Circulation. 2018 Feb;137(8):794-805.

Vaduganathan M, Nagarur A, Qamar A, Patel RB, Navar AM, Peterson ED, Bhatt DL, Fonarow GC, Yancy CW, Butler J. Availability and Use of Shared Data From Cardiometabolic Clinical Trials. Circulation. 2018 Feb 27;137(9):938-947.

Wong YC, Ysselstein D, Krainc D. Mitochondria-lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis.Nature. 2018 Feb;554(7692):382.

Xiao J, Zhu Y, Huddleston S, Li P, Xiao B, Farha OK, Ameer GA. Copper Metal-Organic Framework Nanoparticles Stabilized with Folic Acid Improve Wound Healing in Diabetes. ACS Nano. 2018 Feb 27;12(2):1023-1032.

Zhang SY, Clark NE, Freije CA, Pauwels E, Taggart AJ, Okada S, Mandel H, Garcia P, Ciancanelli MJ, Biran A, Lafaille FG, Tsumura M, Cobat A, Luo JC, Volpi S, Zimmer B, Sakata S, Dinis A, Ohara O, Reino EJG, Dobbs K, Hasek M, Holloway SP, McCammon K, Hussong SA, DeRosa N, Van Skike CE, Katolik A, Lorenzo L, Hyodo M, Faria E, Halwani R, Fukuhara R, Smith GA, Galvan V, Damha MJ, Al-Muhsen S, Itan Y, Boeke JD, Notarangelo LD, Studer L, Kobayashi M, Diogo L, Fairbrother WG, Abel L, Rosenberg BR, Hart PJ, Etzioni A, Casanova JL. Inborn Errors of RNA Lariat Metabolism in Humans with Brainstem Viral Infection. Cell. 2018 Feb;172(5):952.

Zhu S, Zhao DY, Yan L, Jiang WH, Kim JS, Gu BN, Liu QP, Wang R, Xia B, Zhao JC, Song G, Mi WY, Wang RF, Shi XB, Lam HM, Dong XS, Yu JD, Chen KF, Cao Q. BMI1 regulates androgen receptor in prostate cancer independently of the polycomb repressive complex 1. Nature Communications. 2018 Feb;9:13.

Demenais F, Margaritte-Jeannin P, Barnes KC et al. (including Kumar R, Smith LJ). Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marksNature Genetics. 2018 Jan;50(1):42-53.

Eroglu Z, Zaretsky JM, Hu-Lieskovan S, Kim DW, Algazi A, Johnson DB, Liniker E, Kong B, Munhoz R, Rapisuwon S, Gherardini PF, Chmielowski B, Wang XY, Shintaku IP, Wei C, Sosman JA, Joseph RW, Postow MA, Carlino MS, Hwu WJ, Scolyer RA, Messina J, Cochran AJ, Long GV, Ribas A. High response rate to PD-1 blockade in desmoplastic melanomas. Nature2018 Jan;553(7688):347.

Feldman T, Mauri L, Kahwash R, Litwin S, Ricciardi MJ, van der Harst P, Penicka M, Fail PS, Kaye DM, Petrie MC, Basuray A, Hummel SL, Forde-McLean R, Nielsen CD, Lilly S, Massaro JM, Burkhoff D, Shah SJ, Investigators RL-HI. Transcatheter Interatrial Shunt Device for the Treatment of Heart Failure With Preserved Ejection Fraction (REDUCE LAP-HF I Reduce Elevated Left Atrial Pressure in Patients With Heart Failure ): A Phase 2, Randomized, Sham-Controlled Trial. Circulation. 2018 Jan;137(4):364-375.

Feng G, Ingvalson EM, Grieco-Calub TM, Roberts MY, Ryan ME, Birmingham P, Burrowes D, Young NM, Wong PCM. Neural preservation underlies speech improvement from auditory deprivation in young cochlear implant recipients. Proceedings of the National Academy of Sciences of the United States of America. 2018 Jan 30;115(5):E1022-e1031.

Fernandez CV, Mullen EA, Chi YY, Ehrlich PF, Perlman EJ, Kalapurakal JA, Khanna G, Paulino AC, Hamilton TE, Gow KW, Tochner Z, Hoffer FA, Withycombe JS, Shamberger RC, Kim Y, Geller JI, Anderson JR, Grundy PE, Dome JS. Outcome and Prognostic Factors in Stage III Favorable-Histology Wilms Tumor: A Report From the Children's Oncology Group Study AREN0532. Journal of Clinical Oncology. 2018 Jan;36(3):254.

Fiedman DJ, Piccini JP, Wang TR, Zheng JY, Malaisrie C, Holmes DR, Suri RM, Mack MJ, Badhwar V, Jacobs JP, Gaca JG, Chow SC, Peterson ED, Brennan JM. Association Between Left Atrial Appendage Occlusion and Readmission for Thromboembolism Among Patients With Atrial Fibrillation Undergoing Concomitant Cardiac Surgery. JAMA. 2018 Jan;319(4):365-374.

Ganguli A, Ornob A, Spegazzini N, Liu Y, Damhorst G, Ghonge T, Thornton B, Konopka CJ, Dobrucki W, Clare SE, Bhargava R, Smith AM, Kosari F, Bashir R. Pixelated spatial gene expression analysis from tissue. Nature Communications. 2018 Jan;9:9.

Gaydosh L, Schorpp KM, Chen E, Miller GE, Harris KM. College completion predicts lower depression but higher metabolic syndrome among disadvantaged minorities in young adulthood. Proceedings of the National Academy of Sciences of the United States of America. 2018 Jan 2;115(1):109-114.

Grossman DC, Curry SJ, Owens DK, Barry MJ, Davidson KW, Doubeni CA, Epling J, Kemper AR, Krist AH, Kurth AE, Landefeld S, Mangione CM, Phipps MG, Silverstein M, Simon MA, Tseng CW, Force USPST. JAMAScreening for Adolescent Idiopathic Scoliosis US Preventive Services Task Force Recommendation Statement. 2018 Jan;319(2):165-172.

Lu AT, Xue LT, Salfati EL, Chen BH, Ferrucci L, Levy D, Joehanes R, Murabito JM, Kiel DP, Tsai PC, Yet I, Bell JT, Mangino M, Tanaka T, McRae AF, Marioni RE, Visscher PM, Wray NR, Deary IJ, Levine ME, Quach A, Assimes T, Tsao PS, Absher D, Stewart JD, Li Y, Reiner AP, Hou LF, Baccarelli AA, Whitsel EA, Aviv A, Cardona A, Day FR, Wareham NJ, Perry JRB, Ong KK, Raj K, Lunetta KL, Horvath S. GWAS of epigenetic aging rates in blood reveals a critical role for TERT. Nature Communications. 2018 Jan;9:13.

Magdy T, Schuldt AJT, Wu JC, Bernstein D, Burridge PW. Human Induced Pluripotent Stem Cell (hiPSC)-Derived Cells to Assess Drug Cardiotoxicity: Opportunities and Problems. Annual Review of Pharmacology and Toxicology. 2018 Jan 6;58:83-103.

Purnell TS, Luo X, Cooper LA, Massie AB, Kucirka LM, Henderson ML, Gordon EJ, Crews DC, Boulware LE, Segev DL. Association of Race and Ethnicity With Live Donor Kidney Transplantation in the United States From 1995 to 2014. JAMA. 2018 Jan 2;319(1):49-61.

Ramsuran V, Naranbhai V, Horowitz A, Qi Y, Martin MP, Yuki Y, Gao X, Walker-Sperling V, Del Prete GQ, Schneider DK, Lifson JD, Fellay J, Deeks SG, Martin JN, Goedert JJ, Wolinsky SM, Michael NL, Kirk GD, Buchbinder S, Haas D, Ndung'u T, Goulder P, Parham P, Walker BD, Carlson JM, Carrington M. Elevated HLA-A expression impairs HIV control through inhibition of NKG2A-expressing cells. Science2018 Jan 5;359(6371):86-90.

Reges O, Greenland P, Dicker D, Leibowitz M, Hoshen M, Gofer I, Rasmussen-Torvik LJ, Balicer RD. Association of Bariatric Surgery Using Laparoscopic Banding, Roux-en-Y Gastric Bypass, or Laparoscopic Sleeve Gastrectomy vs Usual Care Obesity Management With All-Cause Mortality. JAMA. 2018 Jan;319(3):279-290.

Skinner OS, Haverland NA, Fornelli L, Melani RD, Do Vale LHF, Seckler HS, Doubleday PF, Schachner LF, Srzentic K, Kelleher NL, Compton PD. Top-down characterization of endogenous protein complexes with native proteomics. Nature Chemical Biology. 2018 Jan;14(1):36

Smith BM, Traboulsi H, Austin JHM, Manichaikul A, Hoffman EA, Bleecker ER, Cardoso WV, Cooper C, Couper DJ, Dashnaw SM, Guo J, Han MK, Hansel NN, Hughes EW, Jacobs DR, Jr., Kanner RE, Kaufman JD, Kleerup E, Lin CL, Liu K, Lo Cascio CM, Martinez FJ, Nguyen JN, Prince MR, Rennard S, Rich SS, Simon L, Sun Y, Watson KE, Woodruff PG, Baglole CJ, Barr RG. Human airway branch variation and chronic obstructive pulmonary disease. Proceedings of the National Academy of Sciences of the United States of America. 2018 Jan 30;115(5):E974-e981.

Turcan S, Makarov V, Taranda J, Wang YX, Fabius AWM, Wu W, Zheng YP, El-Amine N, Haddock S, Nanjangud G, LeKaye HC, Brennan C, Cross J, Huse JT, Kelleher NL, Osten P, Thompson CB, Chan TA. Mutant-IDH1-dependent chromatin state reprogramming, reversibility, and persistence. Nature Genetics. 2018 Jan;50(1):62.

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Zhang C, Hediger ML, Albert PS, Grewal J, Sciscione A, Grobman WA, Wing DA, Newman RB, Wapner R, D'Alton ME, Skupski D, Nageotte MP, Ranzini AC, Owen J, Chien EK, Craigo S, Kim S, Grantz KL, Louis GMB. Association of Maternal Obesity With Longitudinal Ultrasonographic Measures of Fetal Growth: Findings From the NICHD Fetal Growth Studies-Singletons. JAMA Pediatrics. 2018 Jan 1;172(1):24-31.

Zhao BB, Mei Y, Cao L, Zhang JX, Sumagin R, Yang J, Gao JH, Schipma MJ, Wang YF, Thorsheim C, Zhao L, Stalker T, Stein B, Wen QJ, Crispino JD, Abrams CS, Ji P. Loss of pleckstrin-2 reverts lethality and vascular occlusions in JAK2(V617F)-positive myeloproliferative neoplasms. Journal of Clinical Investigation. 2018 Jan;128(1):125-140.

Zunke F, Moise AC, Belur NR, Gelyana E, Stojkovska I, Dzaferbegovic H, Toker NJ, Jeon S, Fredriksen K, Mazzulli JR. Reversible Conformational Conversion of alpha-Synuclein into Toxic Assemblies by GlucosylceramideNeuron. 2018 Jan;97(1):92.