Northwestern University Feinberg School of Medicine

High-Impact-Factor Research 2018

Agarwal S, Smith KP, Zhou YZ, Suzuki A, McKenney RJ, Varma D. Cdt1 stabilizes kinetochore-microtubule attachments via an Aurora B kinase-dependent mechanism. Journal of Cell Biology. 2018 Oct;217(10):3446-3463.

Chang JK, Emon MAB, Li CS, Yang Q, Chang HP, Yang Z, Wu CI, Saif MT, Rogers JA. Cytotoxicity and in Vitro Degradation Kinetics of Foundry-Compatible Semiconductor Nanomembranes and Electronic Microcomponents. ACS Nano. 2018 Oct 23;12(10):9721-9732.

Chung CY, Berson A, Kennerdell JR, Sartoris A, Unger T, Porta S, Kim HJ, Smith ER, Shilatifard A, Van Deerlin V, Lee VMY, Chen-Plotkin A, Bonini NM. Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity. Nature Communications. 2018 Oct;9:13.

Condomitti G, Wierda KD, Schroeder A, Rubio SE, Vennekens KM, Orlandi C, Martemyanov KA, Gounko NV, Savas JN, de Wit J. An Input-Specific Orphan Receptor GPR158-HSPG Interaction Organizes Hippocampal Mossy Fiber-CA3 Synapses. Neuron. 2018 Oct;100(1):201.

De T, Alarcon C, Hernandez W, Liko I, Cavallari LH, Duarte JD, Perera MA. Association of Genetic Variants With Warfarin-Associated Bleeding Among Patients of African Descent. JAMA-Journal of the American Medical Association. 2018 Oct;320(16):1670-1677.

Deng JW, Wang P, Chen XP, Cheng HP, Liu JH, Fushimi K, Zhu L, Wu JY. FUS interacts with ATP synthase beta subunit and induces mitochondrial unfolded protein response in cellular and animal models. Proceedings of the National Academy of Sciences of the United States of America. 2018 Oct;115(41):E9678-E9686.

Engel M, Farmer DB, Azpiroz JT, Seo JWT, Kang J, Avouris P, Hersam MC, Krupke R, Steiner M. Graphene-enabled and directed nanomaterial placement from solution for large-scale device integration. Nature Communications. 2018 Oct;9:7.

Evens AM, Advani RH, Helenowski IB, Fanale M, Smith SM, Jovanovic BD, Bociek GR, Klein AK, Winter JN, Gordon LI, Hamlin PA. Multicenter Phase II Study of Sequential Brentuximab Vedotin and Doxorubicin, Vinblastine, and Dacarbazine Chemotherapy for Older Patients With Untreated Classical Hodgkin Lymphoma. Journal of Clinical Oncology. 2018 Oct;36(30):3015.

Fisher OS, Kenney GE, Ross MO, Ro SY, Lemma BE, Batelu S, Thomas PM, Sosnowski VC, DeHart CJ, Kelleher NL, Stemmler TL, Hoffman BM, Rosenzweig AC. Characterization of a long overlooked copper protein from methane- and ammonia-oxidizing bacteria. Nature Communications. 2018 Oct;9:12.

Fonseka CY, Rao DA, Teslovich NC, Korsunsky I, Hannes SK, Slowikowski K, Gurish MF, Donlin LT, Lederer JA, Weinblatt ME, Massarotti EM, Coblyn JS, Helfgott SM, Todd DJ, Bykerk VP, Karlson EW, Ermann J, Lee YC, Brenner MB, Raychaudhuri S. Mixed-effects association of single cells identifies an expanded effector CD4(+) T cell subset in rheumatoid arthritis. Science Translational Medicine. 2018 Oct 17;10(463).

Gallego JA, Perich MG, Naufel SN, Ethier C, Solla SA, Miller LE. Cortical population activity within a preserved neural manifold underlies multiple motor behaviors. Nature Communications. 2018 Oct;9:13.

Gao QQ, Putzbach WE, Murmann AE, Chen S, Sarshad AA, Peter JM, Bartom ET, Hafner M, Peter ME. 6mer seed toxicity in tumor suppressive microRNAs. Nat Commun. 2018 Oct 29;9(1):4504.

Garofalo R, Kuhns LM, Reisner SL, Biello K, Mimiaga MJ. Efficacy of an Empowerment-Based, Group-Delivered HIV Prevention Intervention for Young Transgender Women The Project LifeSkills Randomized Clinical Trial.JAMA Pediatrics. 2018 Oct;172(10):916-923.

Hong SH, Fang S, Lu BC, Nofsinger R, Kawakami Y, Castro GL, Yin YQ, Lin C, Yu RT, Downes M, Belmonte JCI, Shilatifard A, Evans RM. Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis. Proceedings of the National Academy of Sciences of the United States of America. 2018 Oct;115(41):10381-10386.

Krishnan SR, Ray TR, Ayer AB, Ma Y, Gutruf P, Lee K, Lee JY, Wei C, Feng X, Ng B, Abecassis ZA, Murthy N, Stankiewicz I, Freudman J, Stillman J, Kim N, Young G, Goudeseune C, Ciraldo J, Tate M, Huang Y, Potts M, Rogers JA. Epidermal electronics for noninvasive, wireless, quantitative assessment of ventricular shunt function in patients with hydrocephalus. Science Translational Medicine. 2018 Oct 31;10(465).

Li JH, Song EM, Chiang CH, Yu KJ, Koo J, Du HN, Zhong YS, Hill M, Wang C, Zhang JZ, Chen YS, Tian LM, Zhong YD, Fang GH, Viventi J, Rogers JA.Conductively coupled flexible silicon electronic systems for chronic neural electrophysiology. Proceedings of the National Academy of Sciences of the United States of America. 2018 Oct;115(41):E9542-E9549.

Liang K, Smith ER, Aoi Y, Stoltz KL, Katagi H, Woodfin AR, Rendleman EJ, Marshall SA, Murray DC, Wang L, Ozark PA, Mishra RK, Hashizume R, Schiltz GE, Shilatifard A.Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy. Cell. 2018 Oct 18;175(3):766-779.e717.

Louveau A, Herz J, Alme MN, Salvador AF, Dong MQ, Viar KE, Herod SG, Knopp J, Setliff JC, Lupi AL, Da Mesquita S, Frost EL, Gaultier A, Harris TH, Cao R, Hu S, Lukens JR, Smirnov I, Overall CC, Oliver G, Kipnis J. CNS lymphatic drainage and neuroinflammation are regulated by meningeal lymphatic vasculature. Nature Neuroscience. 2018 Oct;21(10):1380.

Lu W, Lakonishok M, Serpinskaya AS, Kirchenbuechler D, Ling SC, Gelfand VI. Ooplasmic flow cooperates with transport and anchorage in Drosophila oocyte posterior determination. Journal of Cell Biology. 2018 Oct;217(10):3497-3511.

Ma Y, Choi J, Hourlier-Fargette A, Xue Y, Chung HU, Lee JY, Wang X, Xie Z, Kang D, Wang H, Han S, Kang SK, Kang Y, Yu X, Slepian MJ, Raj MS, Model JB, Feng X, Ghaffari R, Rogers JA, Huang Y. Relation between blood pressure and pulse wave velocity for human arteries. Proceedings of the National Academy of Sciences of the United States of America. 2018 Oct 30;115(44):11144-11149.

Mas G, Blanco E, Ballare C, Sanso M, Spill YG, Hu DQ, Aoi Y, Le Dily F, Shilatifard A, Marti-Renom MA, Di Croce L. Promoter bivalency favors an open chromatin architecture in embryonic stem cells. Nature Genetics. 2018 Oct;50(10):1452.

Rangasamy SB, Jana M, Roy A, Corbett GT, Kundu M, Chandra S, Mondal S, Dasarathi S, Mufson E, Mishra RK, Luan CH, Bennett DA, Pahan K. Selective disruption of TLR2-MyD88 interaction inhibits inflammation and attenuates Alzheimer's pathology. Journal of Clinical Investigation. 2018 Oct;128(10):4297-4312.

Robson MJ, Quinlan MA, Margolis KG, Gajewski-Kurdziel PA, Veenstra-VanderWeele J, Gershon MD, Watterson DM, Blakely RD. p38 alpha MAPK signaling drives pharmacologically reversible brain and gastrointestinal phenotypes in the SERT Ala56 mouse. Proceedings of the National Academy of Sciences of the United States of America. 2018 Oct;115(43):E10245-E10254.

Saad F, Cella D, Basch E, Hadaschik BA, Mainwaring PN, Oudard S, Graff JN, McQuarrie K, Li S, Hudgens S, Lawson J, Lopez-Gitlitz A, Yu MK, Smith MR, Small EJ. Effect of apalutamide on health-related quality of life in patients with non-metastatic castration-resistant prostate cancer: an analysis of the SPARTAN randomised, placebo-controlled, phase 3 trial. Lancet Oncology. 2018 Oct;19(10):1404-1416.

Song E, Li R, Jin X, Du H, Huang Y, Zhang J, Xia Y, Fang H, Lee YK, Yu KJ, Chang JK, Mei Y, Alam MA, Huang Y, Rogers JA. Ultrathin Trilayer Assemblies as Long-Lived Barriers against Water and Ion Penetration in Flexible Bioelectronic Systems. ACS Nano. 2018 Oct 23;12(10):10317-10326.

US Preventive Services Task Force., Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Davidson KW, Doubeni CA, Epling JW Jr, Grossman DC, Kemper AR, Kubik M, Kurth A, Landefeld CS, Mangione CM, Silverstein M, Simon MA, Tseng CW, Wong JB. Screening for Intimate Partner Violence, Elder Abuse, and Abuse of Vulnerable Adults US Preventive Services Task Force Final Recommendation Statement. Jama-Journal of the American Medical Association. 2018 Oct;320(16):1678-1687.

Weber SC, Kahnt T, Quednow BB, Tobler PN. Frontostriatal pathways gate processing of behaviorally relevant reward dimensions.PLoS Biology. 2018 Oct;16(10):e2005722.

Wei WQ, Li X, Feng Q, Kubo M, Kullo IJ, Peissig PL, Karlson EW, Jarvik GP, Lee MTM, Shang N, Larson EA, Edwards T, Shaffer CM, Mosley JD, Maeda S, Horikoshi M, Ritchie M, Williams MS, Larson EB, Crosslin DR, Bland ST, Pacheco JA, Rasmussen-Torvik LJ, Cronkite D, Hripcsak G, Cox NJ, Wilke RA, Stein CM, Rotter JI, Momozawa Y, Roden DM, Krauss RM, Denny JC. LPA Variants Are Associated With Residual Cardiovascular Risk in Patients Receiving Statins. Circulation. 2018 Oct 23;138(17):1839-1849.

Zhang J, Gajjala S, Agrawal P, Tison GH, Hallock LA, Beussink-Nelson L, Lassen MH, Fan E, Aras MA, Jordan C, Fleischmann KE, Melisko M, Qasim A, Shah SJ, Bajcsy R, Deo RC. Fully Automated Echocardiogram Interpretation in Clinical Practice: Feasibility and Diagnostic Accuracy. Circulation. 2018 Oct;138(16):1623-1635.

Zhao H, Zhou L, Li L, Coon VJ, Chatterton RT, Brooks DC, Jiang E, Liu L, Xu X, Dong Z, DeMayo FJ, Stulberg JJ, Tourtellotte WG, Bulun SE. Shift from androgen to estrogen action causes abdominal muscle fibrosis, atrophy, and inguinal hernia in a transgenic male mouse model. Proceedings of the National Academy of Sciences of the United States of America. 2018 Oct 30;115(44):E10427-e10436.


Aubert G, Ajroud-Driss S, Knight BP, Shah SJ, McNally EM. New DEStiny Revealed: Young Woman Postablation for Wolf-Parkinson-White Syndrome With Recurrent Syncope and Progressive Myopathy. Circulation. 2018 Sep;138(12):1267-1271.

Braun R, Kath WL, Iwanaszko M, Kula-Eversole E, Abbott SM, Reid KJ, Zee PC, Allada R.Universal method for robust detection of circadian state from gene expression. Proceedings of the National Academy of Sciences of the United States of America. 2018 Sep;115(39):E9247-E9256.

Cajigas I, Chakraborty A, Swyter KR, Luo H, Bastidas M, Nigro M, Morris ER, Chen S, VanGompel MJW, Leib D, Kohtz SJ, Martina M, Koh S, Ay F, Kohtz JD. The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially Organizes Megabase Distant Genes in the Developing Forebrain. Molecular Cell. 2018 Sep;71(6):956.

Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Davidson K, Doubeni CA, Epling JW, Grossman DC, Kemper AR, Kubik M, Landefeld CS, Mangione CM, Phipps MG, Silverstein M, Simon MA, Tseng CW, Wong JB, Force USPST. Behavioral Weight Loss Interventions to Prevent Obesity-Related Morbidity and Mortality in Adults US Preventive Services Task Force Recommendation Statement. JAMA. 2018 Sep;320(11):1163-1171.

Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Davidson KW, Doubeni CA, Epling JW, Kemper AR, Kubik M, Kurth AE, Landefeld CS, Mangione CM, Phipps MG, Silverstein M, Simon MA, Tseng CW, Wong JB, Force USPST. Screening for Syphilis Infection in Pregnant Women US Preventive Services Task Force Reaffirmation Recommendation Statement. JAMA. 2018 Sep;320(9):911-917.

Dekleva BM, Kording KP, Miller LE.Single reach plans in dorsal premotor cortex during a two-target task. Nature Communications. 2018 Sep;9:12.

Jalal H, Buchanich JM, Roberts MS, Balmert LC, Zhang K, Burke DS. Changing dynamics of the drug overdose epidemic in the United States from 1979 through 2016. Science. 2018 Sep;361(6408):1218.

Jong SJ, Crequer A, Matos I, Hum D, Gunasekharan V, Lorenzo L, Jabot-Hanin F, Imahorn E, Arias AA, Vahidnezhad H, Youssefian L, Markle JG, Patin E, D'Amico A, Wang CQF, Full F, Ensser A, Leisner TM, Parise LV, Bouaziz M, Maya N, Cadena X, Saka B, Saeidian AH, Aghazadeh N, Zeinali S, Itin P, Krueger JG, Laimins L, Abel L, Fuchs E, Uitto J, Franco J, Burger B, Orth G, Jouanguy E, Casanova JL. The human CIB1-EVER1-EVER2 complex governs keratinocyte-intrinsic immunity to beta-papillomaviruses. Journal of Experimental Medicine. 2018 Sep;215(9):2289-2310.

Kam CY, Dubash AD, Magistrati E, Polo S, Satchell KJF, Sheikh F, Lampe PD, Green KJ.Desmoplakin maintains gap junctions by inhibiting Ras/MAPK and lysosomal degradation of connexin-43. Journal of Cell Biology. 2018 Sep;217(9):3219-3235.

Kim YH, Bagot M, Pinter-Brown L, Rook AH, Porcu P, Horwitz SM, Whittaker S, Tokura Y, Vermeer M, Zinzani PL, Sokol L, Morris S, Kim EJ, Ortiz-Romero PL, Eradat H, Scarisbrick J, Tsianakas A, Elmets C, Dalle S, Fisher DC, Halwani A, Poligone B, Greer J, Fierro MT, Khot A, Moskowitz AJ, Musiek A, Shustov A, Pro B, Geskin LJ, Dwyer K, Moriya J, Leoni M, Humphrey JS, Hudgens S, Grebennik DO, Tobinai K, Duvic M, Investigators M. Mogamulizumab versus vorinostat in previously treated cutaneous T-cell lymphoma (MAVORIC): an international, open-label, randomised, controlled phase 3 trial. Lancet Oncology. 2018 Sep;19(9):1192-1204.

Liu P, Thomson BR, Khalatyan N, Feng L, Liu XR, Savas JN, Quaggin SE, Jin J.Selective permeability of mouse blood-aqueous barrier as determined by N-15-heavy isotope tracing and mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America. 2018 Sep;115(36):9032-9037.

Liu XL, Zhang ZH, Wang LQ, Yakobson BI, Hersam MC. Intermixing and periodic self-assembly of borophene line defects. Nature Materials. 2018 Sep;17(9):783.

Lowe WL, Scholtens DM, Lowe LP, Kuang A, Nodzenski M, Talbot O, Catalano PM, Linder B, Brickman WJ, Clayton P, Deerochanawong C, Hamilton J, Josefson JL, Lashley M, Lawrence JM, Lebenthal Y, Ma R, Maresh M, McCance D, Tam WH, Sacks DA, Dyer AR, Metzger BE, Hapo Follow-Up Study Cooperative R. Association of Gestational Diabetes With Maternal Disorders of Glucose Metabolism and Childhood Adiposity. JAMA. 2018 Sep;320(10):1005-1016.

Maurer MS, Schwartz JH, Gundapaneni B, Elliott PM, Merlini G, Waddington-Cruz M, Kristen AV, Grogan M, Witteles R, Damy T, Drachman BM, Shah SJ, Hanna M, Judge DP, Barsdorf AI, Huber P, Patterson TA, Riley S, Schumacher J, Stewart M, Sultan MB, Rapezzi C, Investigators A-AS. Tafamidis Treatment for Patients with Transthyretin Amyloid Cardiomyopathy. New England Journal of Medicine. 2018 Sep;379(11):1007-1016.

McGurk L, Gomes E, Guo L, Mojsilovic-Petrovic J, Tran V, Kalb RG, Shorter J, Bonini NM. Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization. Molecular Cell. 2018 Sep;71(5):703.

Miller KD, O'Neill A, Gradishar W, Hobday TJ, Goldstein LJ, Mayer IA, Bloom S, Brufsky AM, Tevaarwerk AJ, Sparano JA, Le-Lindqwister NA, Hendricks CB, Northfelt DW, Dang CT, Sledge GW, Jr. Double-Blind Phase III Trial of Adjuvant Chemotherapy With and Without Bevacizumab in Patients With Lymph Node-Positive and High-Risk Lymph Node-Negative Breast Cancer (E5103). Journal of Clinical Oncology. 2018 Sep 1;36(25):2621-2629.

Ou-Yang MH, Kurz JE, Nomura T, Popovic J, Rajapaksha TW, Dong H, Contractor A, Chetkovich DM, Tourtellotte WG, Vassar R.Axonal organization defects in the hippocampus of adult conditional BACE1 knockout mice. Science Translational Medicine. 2018 Sep;10(459):15.

Poulin JF, Caronia G, Hofer C, Cui QL, Helm B, Ramakrishnan C, Chan CS, Dombeck DA, Deisseroth K, Awatramani R.Mapping projections of molecularly defined dopamine neuron subtypes using intersectional genetic approaches. Nature Neuroscience. 2018 Sep;21(9):1260.

Seifert HS.Above and Beyond Watson and Crick: Guanine Quadruplex Structures and Microbes. Annual Review of Microbiology. 2018 Sep 8;72:49-69.

Shigemura M, Lecuona E, Angulo M, Homma T, Rodriguez DA, Gonzalez-Gonzalez FJ, Welch LC, Amarelle L, Kim SJ, Kaminski N, Budinger GRS, Solway J, Sznajder JI. Hypercapnia increases airway smooth muscle contractility via caspase-7-mediated miR-133a-RhoA signaling. Science Translational Medicine. 2018 Sep;10(457):14.

Stoeger T, Gerlach M, Morimoto RI, Nunes Amaral LA. Large-scale investigation of the reasons why potentially important genes are ignored. PLoS Biology. 2018 Sep;16(9):e2006643.

Sun C, Shen M, Chavez AD, Evans AM, Liu XL, Harutyunyan B, Flanders NC, Hersam MC, Bedzyk MJ, de la Cruz MO, Dichtel WR. High aspect ratio nanotubes assembled from macrocyclic iminium salts. Proceedings of the National Academy of Sciences of the United States of America. 2018 Sep;115(36):8883-8888.

Vachon-Presseau E, Berger SE, Abdullah TB, Huang LJ, Cecchi GA, Griffith JW, Schnitzer TJ, Apkarian AV.Brain and psychological determinants of placebo pill response in chronic pain patients. Nature Communications. 2018 Sep;9:15.

Wei JC, Yuan YZ, Chen L, Xu YM, Zhang YH, Wang YJ, Yang YJ, Peek CB, Diebold L, Yang Y, Gao BX, Jin CZ, Melo-Cardenas J, Chandel NS, Zhang DD, Pan H, Zhang KZ, Wang J, He FC, Fang DY. ER-associated ubiquitin ligase HRD1 programs liver metabolism by targeting multiple metabolic enzymes. Nature Communications. 2018 Sep;9:14.

Zhao N, Sebastiano V, Moshkina N, Mena N, Hultquist J, Jimenez-Morales D, Ma YX, Rialdi A, Albrecht R, Fenouil R, Sanchez-Aparicio MT, Ayllon J, Ravisankar S, Haddad B, Ho JSY, Low D, Jin J, Yurchenko V, Prinjha RK, Tarakhovsky A, Squatrito M, Pinto D, Allette K, Byun M, Smith ML, Sebra R, Guccione E, Tumpey T, Krogan N, Greenbaum B, van Bakel H, Garcia-Sastre A, Marazzi I. Influenza virus infection causes global RNAPII termination defects.Nature Structural & Molecular Biology. 2018 Sep;25(9):885.

Zimmer B, Ewaleifoh O, Harschnitz O, Lee YS, Peneau C, McAlpine JL, Liu B, Tchieu J, Steinbeck JA, Lafaille F, Volpi S, Notarangelo LD, Casanova JL, Zhang SY, Smith GA, Studer L. Human iPSC-derived trigeminal neurons lack constitutive TLR3-dependent immunity that protects cortical neurons from HSV-1 infection. Proceedings of the National Academy of Sciences of the United States of America. 2018 Sep;115(37):E8775-E8782.

Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Davidson KW, Doubeni CA, Epling JW, Kemper AR, Kubik M, Landefeld CS, Mangione CM, Phipps MG, Silverstein M, Simon MA, Tseng CW, Wong JB, Force USPST. Screening for Cervical Cancer US Preventive Services Task Force Recommendation Statement. JAMA. 2018 Aug;320(7):674-686.

Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Davidson KW, Doubeni CA, Epling JW, Kemper AR, Kubik M, Landefeld CS, Mangione CM, Silverstein M, Simon MA, Tseng CW, Wong JB, Us Preventive Services Task F. Screening for Atrial Fibrillation With Electrocardiography US Preventive Services Task Force Recommendation Statement. JAMA. 2018 Aug;320(5):478-484.

Fox RJ, Coffey CS, Conwit R, Cudkowicz ME, Gleason T, Goodman A, Klawiter EC, Matsuda K, McGovern M, Naismith RT, Ashokkumar A, Barnes J, Ecklund D, Klingner E, Koepp M, Long JD, Natarajan S, Thornell B, Yankey J, Bermel RA, Debbins JP, Huang X, Jagodnik P, Lowe MJ, Nakamura K, Narayanan S, Sakaie KE, Thoomukuntla B, Zhou X, Krieger S, Alvarez E, Apperson M, Bashir K, Cohen BA, Coyle PK, Delgado S, Dewitt LD, Flores A, Giesser BS, Goldman MD, Jubelt B, Lava N, Lynch SG, Moses H, Ontaneda D, Perumal JS, Racke M, Repovic P, Riley CS, Severson C, Shinnar S, Suski V, Weinstock-Guttman B, Yadav V, Zabeti A. Phase 2 Trial of Ibudilast in Progressive Multiple Sclerosis. New England Journal of Medicine. 2018 Aug 30;379(9):846-855.

Ghosn J, Taiwo B, Seedat S, Autran B, Katlama C. HIV. Lancet. 2018 Aug;392(10148):685-697.

Grobman WA, Rice MM, Reddy UM, Tita ATN, Silver RM, Mallett G, Hill K, Thom EA, El-Sayed YY, Perez-Delboy A, Rouse DJ, Saade GR, Boggess KA, Chauhan SP, Iams JD, Chien EK, Casey BM, Gibbs RS, Srinivas SK, Swamy GK, Simhan HN, Macones GA, Eunice Kennedy Shriver Natl Inst C. Labor Induction versus Expectant Management in Low-Risk Nulliparous Women. New England Journal of Medicine. 2018 Aug;379(6):513-523.

Hlubocky FJ, Sachs GA, Larson ER, Nimeiri HS, Cella D, Wroblewski KE, Ratain MJ, Peppercorn JM, Daugherty CK. Do Patients With Advanced Cancer Have the Ability to Make Informed Decisions for Participation in Phase I Clinical Trials?Journal of Clinical Oncology. 2018 Aug 20;36(24):2483-2491.

Loftfield E, Cornelis MC, Caporaso N, Yu K, Sinha R, Freedman N. Association of Coffee Drinking With Mortality by Genetic Variation in Caffeine Metabolism Findings From the UK Biobank. JAMA Internal Medicine. 2018 Aug;178(8):1086-1097.

Manzano M, Patil A, Waldrop A, Dave SS, Behdad A, Gottwein E. Gene essentiality landscape and druggable oncogenic dependencies in herpesviral primary effusion lymphoma. Nature Communications. 2018 Aug;9:14.

Mayne SL, Widome R, Carroll AJ, Schreiner PJ, Gordon-Larsen P, Jacobs DR, Kershaw KN. Longitudinal Associations of Smoke-Free Policies and Incident Cardiovascular Disease: CARDIA Study. Circulation. 2018 Aug;138(6):557-566.

Meade N, Furey C, Li H, Verma R, Chai QQ, Rollins MG, DiGiuseppe S, Naghavi MH, Walsh D.Poxviruses Evade Cytosolic Sensing through Disruption of an mTORC1-mTORC2 Regulatory Circuit.Cell. 2018 Aug;174(5):1143.

Mente A, O'Donnell M, Rangarajan S, McQueen M, Dagenais G, Wielgosz A, Lear S, Ah STL, Wei L, Diaz R, Avezum A, Lopez-Jaramillo P, Lanas F, Mony P, Szuba A, Iqbal R, Yusuf R, Mohammadifard N, Khatib R, Yusoff K, Ismail N, Gulec S, Rosengren A, Yusufali A, Kruger L, Tsolekile LP, Chifamba J, Dans A, Alhabib KF, Yeates K, Teo K, Yusuf S. Urinary sodium excretion, blood pressure, cardiovascular disease, and mortality: a community-level prospective epidemiological cohort study. Lancet. 2018 Aug;392(10146):496-506.

Mosley JD, Feng QP, Wells QS, Van Driest SL, Shaffer CM, Edwards TL, Bastarache L, Wei WQ, Davis LK, McCarty CA, Thompson W, Chute CG, Jarvik GP, Gordon AS, Palmer MR, Crosslin DR, Larson EB, Carrell DS, Kullo IJ, Pacheco JA, Peissig PL, Brilliant MH, Linneman JG, Namjou B, Williams MS, Ritchie MD, Borthwick KM, Verma SS, Karnes JH, Weiss ST, Wang TJ, Stein CM, Denny JC, Roden DM. A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers. Nature Communications. 2018 Aug;9:11.

Naghavi M, Marczak LB, Kutz M, et al. (including Swaroop, M). Global Mortality From Firearms, 1990-2016. JAMA. 2018 Aug;320(8):792-814.

Persell SD, Karmali KN, Lazar D, Friesema EM, Lee JY, Rademaker A, Kaiser D, Eder M, French DD, Brown T, Wolf MS. Effect of Electronic Health Record-Based Medication Support and Nurse-Led Medication Therapy Management on Hypertension and Medication Self-management A Randomized Clinical Trial. JAMA Internal Medicine. 2018 Aug;178(8):1069-1077.

Sonoda T, Lee SK, Birnbaumer L, Schmidt TM. Melanopsin Phototransduction Is Repurposed by ipRGC Subtypes to Shape the Function of Distinct Visual Circuits. Neuron. 2018 Aug;99(4):754.

Wu H, Rahman HNA, Dong Y, Liu X, Lee Y, Wen A, To KH, Xiao L, Birsner AE, Bazinet L, Wong S, Song K, Brophy ML, Mahamud MR, Chang B, Cai X, Pasula S, Kwak S, Yang W, Bischoff J, Xu J, Bielenberg DR, Dixon JB, D'Amato RJ, Srinivasan RS, Chen H. Epsin deficiency promotes lymphangiogenesis through regulation of VEGFR3 degradation in diabetes. Journal of Clinical Investigation. 2018 Aug 31;128(9):4025-4043.

Zhu Y, Dean AE, Horikoshi N, Heer C, Spitz DR, Gius D. Emerging evidence for targeting mitochondrial metabolic dysfunction in cancer therapy. Journal of Clinical Investigation. 2018 Aug 31;128(9):3682-3691.

Chen FX, Smith ER, Shilatifard A. Born to run: control of transcription elongation by RNA polymerase II. Nature Reviews Molecular Cell Biology. 2018 Jul;19(7):464-478.

Cortes J, Perl AE, Dohner H, Kantarjian H, Martinelli G, Kovacsovics T, Rousselot P, Steffen B, Dombret H, Estey E, Strickland S, Altman JK, Baldus CD, Burnett A, Kramer A, Russell N, Shah NP, Smith CC, Wang ES, Ifrah N, Gammon G, Trone D, Lazzaretto D, Levis M. Quizartinib, an FLT3 inhibitor, as monotherapy in patients with relapsed or refractory acute myeloid leukaemia: an open-label, multicentre, single-arm, phase 2 trial. Lancet Oncology. 2018 Jul;19(7):889-903.

Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Davidson K, Doubeni CA, Epling J, Kemper AR, Kubik M, Landefeld CS, Mangione CM, Silverstein M, Simon MA, Tseng CW, Wong JB, Force USPST. Screening for Peripheral Artery Disease and Cardiovascular Disease Risk Assessment With the Ankle-Brachial Index US Preventive Services Task Force Recommendation Statement. JAMA. 2018 Jul;320(2):177-183.

Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Davidson K, Doubeni CA, Epling JW, Kemper AR, Kubik M, Landefeld S, Mangione CM, Silverstein M, Simon MA, Tseng CW, Wong JB, Force USPST. Risk Assessment for Cardiovascular Disease With Nontraditional Risk Factors US Preventive Services Task Force Recommendation Statement. JAMA. 2018 Jul;320(3):272-280.

Evans IVR, Phillips GS, Alpern ER, Angus DC, Friedrich ME, Kissoon N, Lemeshow S, Levy MM, Parker MM, Terry KM, Watson RS, Weiss SL, Zimmerman J, Seymour CW. Association Between the New York Sepsis Care Mandate and In-Hospital Mortality for Pediatric Sepsis. JAMA. 2018 Jul;320(4):358-367.

Friedman SL, Neuschwander-Tetri BA, Rinella M, Sanyal AJ. Mechanisms of NAFLD development and therapeutic strategies. Nature Medicine. 2018 Jul;24(7):908-922.

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Grossman DC, Curry SJ, Owens DK, Barry M, Caughey AB, Davidson KW, Doubeni CA, Epling JW, Kemper AR, Krist AH, Kubik M, Landefeld S, Mangione CM, Pignone M, Silverstein M, Simon MA, Tseng CW, Force USPST. Interventions to Prevent Falls in Community-Dwelling Older Adults US Preventive Services Task Force Recommendation Statement. JAMA-Journal of the American Medical Association. 2018 Apr;319(16):1696-1704.

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Howard JD, Kahnt T.Identity prediction errors in the human midbrain update reward-identity expectations in the orbitofrontal cortex. Nature Communications. 2018 Apr;9:11.

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Hussain M, Daignault-Newton S, Twardowski PW, Albany C, Stein MN, Kunju LP, Siddiqui J, Wu YM, Robinson D, Lonigro RJ, Cao X, Tomlins SA, Mehra R, Cooney KA, Montgomery B, Antonarakis ES, Shevrin DH, Corn PG, Whang YE, Smith DC, Caram MV, Knudsen KE, Stadler WM, Feng FY, Chinnaiyan AM. Targeting Androgen Receptor and DNA Repair in Metastatic Castration-Resistant Prostate Cancer: Results From NCI 9012. Journal of Clinical Oncology. 2018 Apr 1;36(10):991-999.

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Lee W, Liu Y, Lee Y, Sharma BK, Shinde SM, Kim SD, Nan K, Yan Z, Han MD, Huang YG, Zhang YH, Ahn JH, Rogers JA. Two-dimensional materials in functional three-dimensional architectures with applications in photodetection and imaging. Nature Communications. 2018 Apr;9:9.

Li H, Zhang BH, Lu XG, Tan XY, Jia F, Xiao Y, Cheng ZH, Li Y, Silva DO, Schrekker HS, Zhang K, Mirkin CA. Molecular spherical nucleic acids. Proceedings of the National Academy of Sciences of the United States of America. 2018 Apr;115(17):4340-4344.

Lozoya OA, Martinez-Reyes I, Wang T, Grenet D, Bushel P, Li J, Chandel N, Woychik RP, Santos JH. Mitochondrial nicotinamide adenine dinucleotide reduced (NADH) oxidation links the tricarboxylic acid (TCA) cycle with methionine metabolism and nuclear DNA methylation. PLoS Biology. 2018 Apr;16(4):e2005707.

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Mokdad AH, Ballestros K, Echko M, et al. (including Yano Y). The State of US Health, 1990-2016 Burden of Diseases, Injuries, and Risk Factors Among US States. JAMA-Journal of the American Medical Association. 2018 Apr;319(14):1444-1472.

Morgans AK, Chen YH, Sweeney CJ, Jarrard DF, Plimack ER, Gartrell BA, Carducci MA, Hussain M, Garcia JA, Cella D, DiPaola RS, Patrick-Miller LJ. Quality of Life During Treatment With Chemohormonal Therapy: Analysis of E3805 Chemohormonal Androgen Ablation Randomized Trial in Prostate Cancer. Journal of Clinical Oncology. 2018 Apr;36(11):1088.

Ntai I, Fornelli L, DeHart CJ, Hutton JE, Doubleday PF, Leduc RD, van Nispen AJ, Fellers RT, Whiteley G, Boja ES, Rodriguez H, Kelleher NL. Precise characterization of KRAS4b proteoforms in human colorectal cells and tumors reveals mutation/modification cross-talk. Proceedings of the National Academy of Sciences of the United States of America. 2018 Apr;115(16):4140-4145.

Pandey A, Omar W, Ayers C, LaMonte M, Klein L, Allen NB, Kuller LH, Greenland P, Eaton CB, Gottdiener JS, Lloyd-Jones DM, Berry JD. Sex and Race Differences in Lifetime Risk of Heart Failure With Preserved Ejection Fraction and Heart Failure With Reduced Ejection Fraction. Circulation. 2018 Apr;137(17):1814.

Pool LR, Burgard SA, Needham BL, Elliott MR, Langa KM, de Leon CFM. Association of a Negative Wealth Shock With All-Cause Mortality in Middle-aged and Older Adults in the United States. JAMA-Journal of the American Medical Association. 2018 Apr;319(13):1341-1350.

Procter DJ, Banerjee A, Nukui M, Kruse K, Gaponenko V, Murphy EA, Komarova Y, Walsh D. The HCMV Assembly Compartment Is a Dynamic Golgi-Derived MTOC that Controls Nuclear Rotation and Virus Spread. Developmental Cell. 2018 Apr;45(1):83.

Quillin SJ, Seifert HS. Neisseria gonorrhoeae host adaptation and pathogenesis. Nature Reviews Microbiology. 2018 Apr;16(4):226-240.

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Chai S, Wan X, Ramirez-Navarro A, Tesar PJ, Kaufman ES, Ficker E, George AL, Jr., Deschenes I. Physiological genomics identifies genetic modifiers of long QT syndrome type 2 severity. Journal of Clinical Investigation. 2018 Mar 1;128(3):1043-1056.

Chu LH, Indramohan M, Ratsimandresy RA, Gangopadhyay A, Morris EP, Monack DM, Dorfleutner A, Stehlik C.The oxidized phospholipid oxPAPC protects from septic shock by targeting the non-canonical inflammasome in macrophages. Nature Communications. 2018 Mar;9:16.

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Karmali KN, Lloyd-Jones DM, van der Leeuw J, Goff DC, Jr., Yusuf S, Zanchetti A, Glasziou P, Jackson R, Woodward M, Rodgers A, Neal BC, Berge E, Teo K, Davis BR, Chalmers J, Pepine C, Rahimi K, Sundstrom J. Blood pressure-lowering treatment strategies based on cardiovascular risk versus blood pressure: A meta-analysis of individual participant data. PLoS Medicine. 2018 Mar;15(3):e1002538.

Kenney GE, Dassama LMK, Pandelia ME, Gizzi AS, Martinie RJ, Gao P, DeHart CJ, Schachner LF, Skinner OS, Ro SY, Zhu X, Sadek M, Thomas PM, Almo SC, Bollinger JM, Krebs C, Kelleher NL, Rosenzweig AC. The biosynthesis of methanobactin. Science. 2018 Mar;359(6382):1411.

Kim Y, Bravo E, Thirnbeck CK, Smith-Mellecker LA, Kim SH, Gehlbach BK, Laux LC, Zhou X, Nordli DR, Jr., Richerson GB. Severe peri-ictal respiratory dysfunction is common in Dravet syndrome. Journal of Clinical Investigation. 2018 Mar 1;128(3):1141-1153.

Ma XT, Liu Y, Liu YL, Alexandrov LB, Edmonson MN, Gawad C, Zhou X, Li YJ, Rusch MC, Easton J, Huether R, Gonzalez-Pena V, Wilkinson MR, Hermida LC, Davis S, Sioson E, Pounds S, Cao XY, Ries RE, Wang ZM, Chen X, Dong L, Diskin SJ, Smith MA, Auvil JMG, Meltzer PS, Lau CC, Perlman EJ, Maris JM, Meshinchi S, Hunger SP, Gerhard DS, Zhang JH. Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours. Nature. 2018 Mar;555(7696):371.

Martin RW, Des Soye BJ, Kwon YC, Kay J, Davis RG, Thomas PM, Majewska NI, Chen CX, Marcum RD, Weiss MG, Stoddart AE, Amiram M, Charna AKR, Patel JR, Isaacs FJ, Kelleher NL, Hong SH, Jewett MC. Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids. Nature Communications. 2018 Mar;9:9.

McQuade JL, Daniel CR, Hess KR, et al. (including Sosman JA). Association of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysis. Lancet Oncology. 2018 Mar;19(3):310-322. 

Mobadersany P, Yousefi S, Amgad M, Gutman DA, Barnholtz-Sloan JS, Velazquez Vega JE, Brat DJ, Cooper LAD. Predicting cancer outcomes from histology and genomics using convolutional networks. Proceedings of the National Academy of Sciences of the United States of America. 2018 Mar 27;115(13):E2970-e2979. 

Nekrasova O, Harmon RM, Broussard JA, Koetsier JL, Godsel LM, Fitz GN, Gardel ML, Green KJ.Desmosomal cadherin association with Tctex-1 and cortactin-Arp2/3 drives perijunctional actin polymerization to promote keratinocyte delamination. Nature Communications. 2018 Mar;9:18. 

O'Leary B, Hrebien S, Morden JP, Beaney M, Fribbens C, Huang X, Liu Y, Bartlett CH, Koehler M, Cristofanilli M, Garcia-Murillas I, Bliss JM, Turner NC. Early circulating tumor DNA dynamics and clonal selection with palbociclib and fulvestrant for breast cancer. Nature Communications. 2018 Mar 1;9(1):896. 

Robida PA, Puzzovio PG, Pahima H, Levi-Schaffer F, Bochner BS. Human eosinophils and mast cells: Birds of a feather flock together. Immunological Reviews. 2018 Mar;282(1):151-167. 

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Traina TA, Miller K, Yardley DA, Eakle J, Schwartzberg LS, O'Shaughnessy J, Gradishar W, Schmid P, Winer E, Kelly C, Nanda R, Gucalp A, Awada A, Garcia-Estevez L, Trudeau ME, Steinberg J, Uppal H, Tudor IC, Peterson A, Cortes J. Enzalutamide for the Treatment of Androgen Receptor-Expressing Triple-Negative Breast Cancer. Journal of Clinical Oncology. 2018 Mar 20;36(9):884-890. 

Trombetti A, Hars M, Hsu FC, Reid KF, Church TS, Gill TM, King AC, Liu CK, Manini TM, McDermott MM, Newman AB, Rejeski WJ, Guralnik JM, Pahor M, Fielding RA, Investigators LS. Effect of Physical Activity on Frailty Secondary Analysis of a Randomized Controlled Trial.Annals of Internal Medicine. 2018 Mar;168(5):309. 

Zhang X, Yoon JY, Morley M, McLendon JM, Mapuskar KA, Gutmann R, Mehdi H, Bloom HL, Dudley SC, Ellinor PT, Shalaby AA, Weiss R, Tang WHW, Moravec CS, Singh M, Taylor AL, Yancy CW, Feldman AM, McNamara DM, Irani K, Spitz DR, Breheny P, Margulies KB, London B, Boudreau RL. A common variant alters SCN5A-miR-24 interaction and associates with heart failure mortality. Journal of Clinical Investigation. 2018 Mar 1;128(3):1154-1163.

Albers GW, Marks MP, Kemp S, Christensen S, Tsai JP, Ortega-Gutierrez S, McTaggart RA, Torbey MT, Kim-Tenser M, Leslie-Mazwi T, Sarraj A, Kasner SE, Ansari SA, Yeatts SD, Hamilton S, Mlynash M, Heit JJ, Zaharchuk G, Kim S, Carrozzella J, Palesch YY, Demchuk AM, Bammer R, Lavori PW, Broderick JP, Lansberg MG, Investigators D. Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging. New England Journal of Medicine. 2018 Feb;378(8):708-718.

Brown PD, Ahluwalia MS, Khan OH, Asher AL, Wefel JS, Gondi V. Whole-Brain Radiotherapy for Brain Metastases: Evolution or Revolution? Journal of Clinical Oncology. 2018 Feb;36(5):483.

Burgart AM, Magnus D, Tabor HK, Paquette EDT, Frader J, Glover JJ, Jackson BM, Harrison CH, Urion DK, Graham RJ, Brandsema JF, Feudtner C. Ethical Challenges Confronted When Providing Nusinersen Treatment for Spinal Muscular Atrophy. JAMA Pediatrics. 2018 Feb;172(2):188-192.

Giri VN, Knudsen KE, Kelly WK, et al. (including Catalona WJ and Schaeffer E). Role of Genetic Testing for Inherited Prostate Cancer Risk: Philadelphia Prostate Cancer Consensus Conference 2017. Journal of Clinical Oncology. 2018 Feb 1;36(4):414-424.

Gong YX, Lazaris C, Sakellaropoulos T, Lozano A, Kambadur P, Ntziachristos P, Aifantis I, Tsirigos A. Stratification of TAD boundaries reveals preferential insulation of super-enhancers by strong boundaries. Nature Communications. 2018 Feb;9:12.

Goode B, Mondal G, Hyun M, Ruiz DG, Lin YH, Van Ziffle J, Joseph NM, Onodera C, Talevich E, Grenert JP, Hewedi IH, Snuderl M, Brat DJ, Kleinschmidt-DeMasters BK, Rodriguez FJ, Louis DN, Yong WH, Lopes MB, Rosenblum MK, Butowski N, Tihan T, Bollen AW, Phillips JJ, Wiita AP, Yeh I, Jacobson MP, Bastian BC, Perry A, Solomon DA. A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle. Nature Communications. 2018 Feb;9:8.

Grossman DC, Curry SJ, Owens DK, Barry MJ, Davidson KW, Doubeni CA, Epling JW, Kemper AR, Krist AH, Kurth AE, Landefeld S, Mangione CM, Phipps MG, Silverstein M, Simon MA, Tseng CW, Force USPST. Screening for Ovarian Cancer US Preventive Services Task Force Recommendation Statement. JAMA. 2018 Feb;319(6):588-594.

Harshman LC, Chen YH, Liu G, Carducci MA, Jarrard D, Dreicer R, Hahn N, Garcia JA, Hussain M, Shevrin D, Eisenberger M, Kohli M, Plimack ER, Cooney M, Vogelzang NJ, Picus J, Dipaola R, Sweeney CJ. Seven-Month Prostate-Specific Antigen Is Prognostic in Metastatic Hormone-Sensitive Prostate Cancer Treated With Androgen Deprivation With or Without Docetaxel. Journal of Clinical Oncology. 2018 Feb 1;36(4):376-382.

Huffman MD, Mohanan PP, Devarajan R, Baldridge AS, Kondal D, Zhao LH, Ali M, Krishnan MN, Natesan S, Gopinath R, Viswanathan S, Stigi J, Joseph J, Chozhakkat S, Lloyd-Jones DM, Prabhakaran D, Acute Coronary Syndrome Q. Effect of a Quality Improvement Intervention on Clinical Outcomes in Patients in India With Acute Myocardial Infarction The ACS QUIK Randomized Clinical Trial. JAMA. 2018 Feb;319(6):567-578.

Karabin NB, Allen S, Kwon HK, Bobbala S, Firlar E, Shokuhfar T, Shull KR, Scott EA. Sustained micellar delivery via inducible transitions in nanostructure morphology. Nature Communications. 2018 Feb;9:13.

Laiteerapong N, Cooper JM, Skandari MR, Clarke PM, Winn AN, Naylor RN, Huang ES. Individualized Glycemic Control for U. S. Adults With Type 2 Diabetes A Cost-Effectiveness Analysis. Annals of Internal Medicine. 2018 Feb;168(3):170.

Larkin J, Minor D, D'Angelo S, Neyns B, Smylie M, Miller WH, Jr., Gutzmer R, Linette G, Chmielowski B, Lao CD, Lorigan P, Grossmann K, Hassel JC, Sznol M, Daud A, Sosman J, Khushalani N, Schadendorf D, Hoeller C, Walker D, Kong G, Horak C, Weber J. Overall Survival in Patients With Advanced Melanoma Who Received Nivolumab Versus Investigator's Choice Chemotherapy in CheckMate 037: A Randomized, Controlled, Open-Label Phase III Trial. Journal of Clinical Oncology. 2018 Feb 1;36(4):383-390.

Li R, Guiney LM, Chang CH, Mansukhani ND, Ji Z, Wang X, Liao YP, Jiang W, Sun B, Hersam MC, Nel AE, Xia T. Surface Oxidation of Graphene Oxide Determines Membrane Damage, Lipid Peroxidation, and Cytotoxicity in Macrophages in a Pulmonary Toxicity Model. ACS Nano. 2018 Feb 27;12(2):1390-1402.

Lin QY, Mason JA, Li ZY, Zhou WJ, O'Brien MN, Brown KA, Jones MR, Butun S, Lee B, Dravid VP, Aydin K, Mirkin CA. Building superlattices from individual nanoparticles via template-confined DNA-mediated assembly. Science. 2018 Feb;359(6376):669-672.

Linehan JL, Harrison OJ, Han SJ, Byrd AL, Vujkovic-Cvijin I, Villarino AV, Sen SK, Shaik J, Smelkinson M, Tamoutounour S, Collins N, Bouladoux N, Dzutsev A, Rosshart SP, Arbuckle JH, Wang CR, Kristie TM, Rehermann B, Trinchieri G, Brenchley JM, O'Shea JJ, Belkaid Y. Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair. Cell. 2018 Feb;172(4):784.

Lu LY, Gutruf P, Xia L, Bhatti DL, Wang XY, Vazquez-Guardado A, Ning X, Shen XR, Sang T, Ma RX, Pakeltis G, Sobczak G, Zhang H, Seo DO, Xue MT, Yin L, Chanda D, Sheng X, Bruchas MR, Rogers JA. Wireless optoelectronic photometers for monitoring neuronal dynamics in the deep brain. Proceedings of the National Academy of Sciences of the United States of America. 2018 Feb;115(7):E1374-E1383.

Morgans AK. Optimization of Risk Stratification in Localized Prostate Cancer. Journal of Clinical Oncology. 2018 Feb;36(6):528.

Moriguchi S, Ishizuka T, Yabuki Y, Shioda N, Sasaki Y, Tagashira H, Yawo H, Yeh JZ, Sakagami H, Narahashi T, Fukunaga K. Blockade of the K-ATP channel Kir6.2 by memantine represents a novel mechanism relevant to Alzheimer's disease therapy. Molecular Psychiatry. 2018 Feb;23(2):211-221.

Radvansky BA, Dombeck DA. An olfactory virtual reality system for mice. Nature Communications. 2018 Feb 26;9(1):839.

Russi AE, Ebel ME, Yang YC, Brown MA. Male-specific IL-33 expression regulates sex-dimorphic EAE susceptibility. Proceedings of the National Academy of Sciences of the United States of America. 2018 Feb;115(7):E1520-E1529.

Saadalla AM, Osman A, Gurish MF, Dennis KL, Blatner NR, Pezeshki A, McNagny KM, Cheroutre H, Gounari F, Khazaie K. Mast cells promote small bowel cancer in a tumor stage-specific and cytokine-dependent manner. Proceedings of the National Academy of Sciences of the United States of America. 2018 Feb;115(7):1588-1592.

Sangwan VK, Lee HS, Bergeron H, Balla I, Beck ME, Chen KS, Hersam MC. Multi-terminal memtransistors from polycrystalline monolayer molybdenum disulfide. Nature. 2018 Feb;554(7693):500.

Souma T, Thomson BR, Heinen S, Carota IA, Yamaguchi S, Onay T, Liu P, Ghosh AK, Li CJ, Eremina V, Hong YK, Economides AN, Vestweber D, Peters KG, Jin J, Quaggin SE. Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP. Proceedings of the National Academy of Sciences of the United States of America. 2018 Feb;115(6):1298-1303.

Spratt DE, Zhang JB, Santiago-Jimenez M, Dess RT, Davis JW, Den RB, Dicker AP, Kane CJ, Pollack A, Stoyanova R, Abdollah F, Ross AE, Cole A, Uchio E, Randall JM, Nguyen H, Zhao SG, Mehra R, Glass AG, Lam LLC, Chelliserry J, du Plessis M, Choeurng V, Aranes M, Kolisnik T, Margrave J, Alter J, Jordan J, Buerki C, Yousefi K, Haddad Z, Davicioni E, Trabulsi EJ, Loeb S, Tewari A, Carroll PR, Weinmann S, Schaeffer EM, Klein EA, Karnes RJ, Feng FY, Nguyen PL. Development and Validation of a Novel Integrated Clinical-Genomic Risk Group Classification for Localized Prostate Cancer. Journal of Clinical Oncology. 2018 Feb;36(6):581.

Thiagarajan PS, Sinyuk M, Turaga SM, Mulkearns-Hubert EE, Hale JS, Rao V, Demelash A, Saygin C, China A, Alban TJ, Hitomi M, Torre-Healy LA, Alvarado AG, Jarrar A, Wiechert A, Adorno-CruzV, Fox PL, Calhoun BC, Guan JL, Liu HP, Reizes O, Lathia JD. Cx26 drives self-renewal in triple-negative breast cancer via interaction with NANOG and focal adhesion kinase. Nature Communications. 2018 Feb;9:14.

Vaccarino V, Sullivan S, Hammadah M, Wilmot K, Al Mheid I, Ramadan R, Elon L, Pimple PM, Garcia EV, Nye J, Shah AJ, Alkhoder A, Levantsevych O, Gay H, Obideen M, Huang MX, Lewis TT, Bremner JD, Quyyumi AA, Raggi P. Mental Stress-Induced-Myocardial Ischemia in Young Patients With Recent Myocardial Infarction Sex Differences and Mechanisms. Circulation. 2018 Feb;137(8):794-805.

Vaduganathan M, Nagarur A, Qamar A, Patel RB, Navar AM, Peterson ED, Bhatt DL, Fonarow GC, Yancy CW, Butler J. Availability and Use of Shared Data From Cardiometabolic Clinical Trials. Circulation. 2018 Feb 27;137(9):938-947.

Wong YC, Ysselstein D, Krainc D. Mitochondria-lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis.Nature. 2018 Feb;554(7692):382.

Xiao J, Zhu Y, Huddleston S, Li P, Xiao B, Farha OK, Ameer GA. Copper Metal-Organic Framework Nanoparticles Stabilized with Folic Acid Improve Wound Healing in Diabetes. ACS Nano. 2018 Feb 27;12(2):1023-1032.

Zhang SY, Clark NE, Freije CA, Pauwels E, Taggart AJ, Okada S, Mandel H, Garcia P, Ciancanelli MJ, Biran A, Lafaille FG, Tsumura M, Cobat A, Luo JC, Volpi S, Zimmer B, Sakata S, Dinis A, Ohara O, Reino EJG, Dobbs K, Hasek M, Holloway SP, McCammon K, Hussong SA, DeRosa N, Van Skike CE, Katolik A, Lorenzo L, Hyodo M, Faria E, Halwani R, Fukuhara R, Smith GA, Galvan V, Damha MJ, Al-Muhsen S, Itan Y, Boeke JD, Notarangelo LD, Studer L, Kobayashi M, Diogo L, Fairbrother WG, Abel L, Rosenberg BR, Hart PJ, Etzioni A, Casanova JL. Inborn Errors of RNA Lariat Metabolism in Humans with Brainstem Viral Infection. Cell. 2018 Feb;172(5):952.

Zhu S, Zhao DY, Yan L, Jiang WH, Kim JS, Gu BN, Liu QP, Wang R, Xia B, Zhao JC, Song G, Mi WY, Wang RF, Shi XB, Lam HM, Dong XS, Yu JD, Chen KF, Cao Q. BMI1 regulates androgen receptor in prostate cancer independently of the polycomb repressive complex 1. Nature Communications. 2018 Feb;9:13.

Demenais F, Margaritte-Jeannin P, Barnes KC et al. (including Kumar R, Smith LJ). Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marksNature Genetics. 2018 Jan;50(1):42-53.

Eroglu Z, Zaretsky JM, Hu-Lieskovan S, Kim DW, Algazi A, Johnson DB, Liniker E, Kong B, Munhoz R, Rapisuwon S, Gherardini PF, Chmielowski B, Wang XY, Shintaku IP, Wei C, Sosman JA, Joseph RW, Postow MA, Carlino MS, Hwu WJ, Scolyer RA, Messina J, Cochran AJ, Long GV, Ribas A. High response rate to PD-1 blockade in desmoplastic melanomas. Nature2018 Jan;553(7688):347.

Feldman T, Mauri L, Kahwash R, Litwin S, Ricciardi MJ, van der Harst P, Penicka M, Fail PS, Kaye DM, Petrie MC, Basuray A, Hummel SL, Forde-McLean R, Nielsen CD, Lilly S, Massaro JM, Burkhoff D, Shah SJ, Investigators RL-HI. Transcatheter Interatrial Shunt Device for the Treatment of Heart Failure With Preserved Ejection Fraction (REDUCE LAP-HF I Reduce Elevated Left Atrial Pressure in Patients With Heart Failure ): A Phase 2, Randomized, Sham-Controlled Trial. Circulation. 2018 Jan;137(4):364-375.

Feng G, Ingvalson EM, Grieco-Calub TM, Roberts MY, Ryan ME, Birmingham P, Burrowes D, Young NM, Wong PCM. Neural preservation underlies speech improvement from auditory deprivation in young cochlear implant recipients. Proceedings of the National Academy of Sciences of the United States of America. 2018 Jan 30;115(5):E1022-e1031.

Fernandez CV, Mullen EA, Chi YY, Ehrlich PF, Perlman EJ, Kalapurakal JA, Khanna G, Paulino AC, Hamilton TE, Gow KW, Tochner Z, Hoffer FA, Withycombe JS, Shamberger RC, Kim Y, Geller JI, Anderson JR, Grundy PE, Dome JS. Outcome and Prognostic Factors in Stage III Favorable-Histology Wilms Tumor: A Report From the Children's Oncology Group Study AREN0532. Journal of Clinical Oncology. 2018 Jan;36(3):254.

Fiedman DJ, Piccini JP, Wang TR, Zheng JY, Malaisrie C, Holmes DR, Suri RM, Mack MJ, Badhwar V, Jacobs JP, Gaca JG, Chow SC, Peterson ED, Brennan JM. Association Between Left Atrial Appendage Occlusion and Readmission for Thromboembolism Among Patients With Atrial Fibrillation Undergoing Concomitant Cardiac Surgery. JAMA. 2018 Jan;319(4):365-374.

Ganguli A, Ornob A, Spegazzini N, Liu Y, Damhorst G, Ghonge T, Thornton B, Konopka CJ, Dobrucki W, Clare SE, Bhargava R, Smith AM, Kosari F, Bashir R. Pixelated spatial gene expression analysis from tissue. Nature Communications. 2018 Jan;9:9.

Gaydosh L, Schorpp KM, Chen E, Miller GE, Harris KM. College completion predicts lower depression but higher metabolic syndrome among disadvantaged minorities in young adulthood. Proceedings of the National Academy of Sciences of the United States of America. 2018 Jan 2;115(1):109-114.

Grossman DC, Curry SJ, Owens DK, Barry MJ, Davidson KW, Doubeni CA, Epling J, Kemper AR, Krist AH, Kurth AE, Landefeld S, Mangione CM, Phipps MG, Silverstein M, Simon MA, Tseng CW, Force USPST. JAMAScreening for Adolescent Idiopathic Scoliosis US Preventive Services Task Force Recommendation Statement. 2018 Jan;319(2):165-172.

Lu AT, Xue LT, Salfati EL, Chen BH, Ferrucci L, Levy D, Joehanes R, Murabito JM, Kiel DP, Tsai PC, Yet I, Bell JT, Mangino M, Tanaka T, McRae AF, Marioni RE, Visscher PM, Wray NR, Deary IJ, Levine ME, Quach A, Assimes T, Tsao PS, Absher D, Stewart JD, Li Y, Reiner AP, Hou LF, Baccarelli AA, Whitsel EA, Aviv A, Cardona A, Day FR, Wareham NJ, Perry JRB, Ong KK, Raj K, Lunetta KL, Horvath S. GWAS of epigenetic aging rates in blood reveals a critical role for TERT. Nature Communications. 2018 Jan;9:13.

Magdy T, Schuldt AJT, Wu JC, Bernstein D, Burridge PW. Human Induced Pluripotent Stem Cell (hiPSC)-Derived Cells to Assess Drug Cardiotoxicity: Opportunities and Problems. Annual Review of Pharmacology and Toxicology. 2018 Jan 6;58:83-103.

Purnell TS, Luo X, Cooper LA, Massie AB, Kucirka LM, Henderson ML, Gordon EJ, Crews DC, Boulware LE, Segev DL. Association of Race and Ethnicity With Live Donor Kidney Transplantation in the United States From 1995 to 2014. JAMA. 2018 Jan 2;319(1):49-61.

Ramsuran V, Naranbhai V, Horowitz A, Qi Y, Martin MP, Yuki Y, Gao X, Walker-Sperling V, Del Prete GQ, Schneider DK, Lifson JD, Fellay J, Deeks SG, Martin JN, Goedert JJ, Wolinsky SM, Michael NL, Kirk GD, Buchbinder S, Haas D, Ndung'u T, Goulder P, Parham P, Walker BD, Carlson JM, Carrington M. Elevated HLA-A expression impairs HIV control through inhibition of NKG2A-expressing cells. Science2018 Jan 5;359(6371):86-90.

Reges O, Greenland P, Dicker D, Leibowitz M, Hoshen M, Gofer I, Rasmussen-Torvik LJ, Balicer RD. Association of Bariatric Surgery Using Laparoscopic Banding, Roux-en-Y Gastric Bypass, or Laparoscopic Sleeve Gastrectomy vs Usual Care Obesity Management With All-Cause Mortality. JAMA. 2018 Jan;319(3):279-290.

Skinner OS, Haverland NA, Fornelli L, Melani RD, Do Vale LHF, Seckler HS, Doubleday PF, Schachner LF, Srzentic K, Kelleher NL, Compton PD. Top-down characterization of endogenous protein complexes with native proteomics. Nature Chemical Biology. 2018 Jan;14(1):36

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