The mission of the Stem Cell Core Facility is to enable scientists at Feinberg School of Medicine and Northwestern University to conduct research using human embryonic (ESCs) and induced pluripotent stem cells (iPSCs). Patient-specific iPSCs offer unprecedented opportunities to study human developmental processes and disease, using human stem cell-derived somatic cells under each person’s unique genetic constellation. They also represent a unique and very important source of cells for cell replacement therapy. The facility offers reprogramming of primary skin fibroblast cells and peripheral blood mononuclear cells (PBMCs), as well as training in essential culture techniques for human pluripotent stem cells.
- hiPSC line generation using non-integrating methods, with further characterization.
- 2-day long hands-on class teaching basic methods of culturing Human Embryonic and Induced Pluripotent Stem Cells (hESC).
- Distributing hESC and hiPSC from our own bank.
- Using the facility to culture and expand your hESC and iPSCs.
- Provide consultation and support for stem cell projects
- Gene-targeting in iPSCs using the CRISPR/Cas9 to generate single gene knockouts
For additional services please contact the scientific director.
All manuscripts and grants presenting work supported by this core should include the following acknowledgement:
"This work was supported by the Stem Cell Core Facility at Northwestern University Feinberg School of Medicine."
Department of Neurology
Feinberg School of Medicine
303 E. Superior Avenue, Lurie, 10-232
Chicago, IL 60611-3008