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Microsurgery and Preclinical Research Core

Microsurgery Home Page


The mission of the Comprehensive Transplant Center (CTC) Microsurgery Core is to provide comprehensive microsurgery services for basic and preclinical animal research. We offer a variety of acute and chronic surgical models and companion blood gas/chemistry assays for use in mechanistic studies and drug discovery. Our microsurgeons have extensive experience in performing sophisticated surgical procedures, such as vascularized organ transplantation in rodents, and are available to assist in the creation of the most innovative in vivo animal models. In addition, we offer technical training and consultations on any issues pertaining to microsurgical techniques.

Services Offered

Surgical Models
  • Kidney transplantation
  • Liver transplantation
  • Skin transplantation
  • Aortic transplantation
  • Cardiac transplantation
  • Lung transplant
  • Short bowel syndrome
  • Organ ischemic/reperfusion models (hepatic, renal, intestinal )
  • Thymectomy
  • Model of arterial malformation
  • Carotid balloon injury models
  • Cardiac injury models
  • 5/6 Nephrectomy
  • Unilateral ureteral obstruction
  • Carotid Artery Surgery
  • Parabiosis models
  • Islet isolation and transplantation
Companion services
  • Drug deliveries (including intravenous and intracecal injections)
  • Serial blood collections (retro-orbital or tail vein, cardiac picture)
  • Blood gas and chemistry assays (hepatic, renal, hormone)

Request form is available here



Zheng Jenny Zhang, MD, MS


Tarry Building, 11-753
320 East Superior St
Chicago, IL 60611


All manuscripts and grants presenting work supported by this core should include the following acknowledgement:

"Surgical services were provided by the Northwestern University Comprehensive Transplant Center Microsurgery Core"