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Northwestern University Feinberg School of Medicine
Research

Keck Biophysics Facility

Mission

The Keck Biophysics Facility offers access to a collection of  advanced instruments for integrated studies of the structure, dynamics and interactions of biological and synthetic macro-molecules. The Keck Facility provides research groups at Northwestern with state of the art equipment, outstanding services, specialized training and  technical expertise.

Equipment Available

Services Offered

  • Training
  • Assistance with experimental design, sample preparation and data analysis
  • Technical expertise, written manuals, guidelines and application notes
  • Staff -service options available on most instruments
  • Specialized staff services for advanced biophysical characterization of:
    • Proteins - solubility, oligomeric state, secondary, tertiary structure assessments
    • Drug-Target Interactions - binding affinity (KD), kinetic rate constants (kon, koff) thermodynamic parameters (ΔG, ΔH, ΔS), EC50 measurements, specificity and stoichiometry assays
  • Consultation and assistance
  • Support letters for grant applications and research proposals
  • Tours and presentations of the facility for faculty or postdoctoral candidates

Acknowledgement

All manuscripts and grants presenting work supported by this core should include the following acknowledgement:

"This work was supported by the Northwestern University Keck Biophysics Facility and a Cancer Center Support Grant (NCI CA060553)."

Keck

Keck Biophysics Home Page

Order from Keck

Contact

Arabela Grigorescu, PhD  
Director
(847) 491-7610


Location

The Keck Biophysics Facility is located on the Evanston Campus, in Cook Hall, Rooms 4106 and 4118S.

The office is located in Cook Hall, Room 4134.

All instruments are accessible to trained users on a 24/7 basis.