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Keck Biophysics Facility

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Mission

The Keck Biophysics Facility offers access to a collection of  advanced instruments for integrated studies of the structure, dynamics and interactions of biological and synthetic macro-molecules. The Keck Facility provides research groups at Northwestern with state of the art equipment, outstanding services, specialized training and  technical expertise.

Equipment Available

Services Offered

  • Training
  • Assistance with experimental design, sample preparation and data analysis
  • Technical expertise, written manuals, guidelines and application notes
  • Staff -service options available on most instruments
  • Specialized staff services for advanced biophysical characterization of:
    • Proteins - solubility, oligomeric state, secondary, tertiary structure assessments
    • Drug-Target Interactions - binding affinity (KD), kinetic rate constants (kon, koff) thermodynamic parameters (ΔG, ΔH, ΔS), EC50 measurements, specificity and stoichiometry assays
  • Consultation and assistance
  • Support letters for grant applications and research proposals
  • Tours and presentations of the facility for faculty or postdoctoral candidates

Contact

Arabela Grigorescu, PhD
Director
(847) 491-7610

Location

Facility: Cook Hall, Rooms 4106 and 4118S, Evanston

Office: Cook Hall, Room 4134, Evanston

Most instruments are accessible to trained users on a 24/7 basis

Acknowledgement

All manuscripts and grants presenting work supported by this core should include the following acknowledgement:

"This work was supported by the Northwestern University Keck Biophysics Facility and a Cancer Center Support Grant (NCI CA060553)."