High-Impact- Factor Research 2019

Barthel FP, Johnson KC, Varn FS, Moskalik AD, Tanner G, Kocakavuk E, Anderson KJ, Abiola O, Aldape K, Alfaro KD, Alpar D, Amin SB, Ashley DM, Bandopadhayay P, Barnholtz-Sloan JS, Beroukhim R, Bock C, Brastianos PK, Brat DJ, Brodbelt AR, Bruns AF, Bulsara KR, Chakrabarty A, Chakravarti A, Chuang JH, Claus EB, Cochran EJ, Connelly J, Costello JF, Finocchiaro G, Fletcher MN, French PJ, Gan HK, Gilbert MR, Gould PV, Grimmer MR, Iavarone A, Ismail A, Jenkinson MD, Khasraw M, Kim H, Kouwenhoven MCM, LaViolette PS, Li M, Lichter P, Ligon KL, Lowman AK, Malta TM, Mazor T, McDonald KL, Molinaro AM, Nam DH, Nayyar N, Ng HK, Ngan CY, Niclou SP, Niers JM, Noushmehr H, Noorbakhsh J, Ormond DR, Park CK, Poisson LM, Rabadan R, Radlwimmer B, Rao G, Reifenberger G, Sa JK, Schuster M, Shaw BL, Short SC, Smitt PAS, Sloan AE, Smits M, Suzuki H, Tabatabai G, Van Meir EG, Watts C, Weller M, Wesseling P, Westerman BA, Widhalm G, Woehrer A, Yung WKA, Zadeh G, Huse JT, De Groot JF, Stead LF, Verhaak RGW. Longitudinal molecular trajectories of diffuse glioma in adults. Nature. 2019 Dec;576(7785):112-120.

Bostick JW, Wang Y, Shen Z, Ge Y, Brown J, Chen ZE, Mohamadzadeh M, Fox JG, Zhou L. Dichotomous regulation of group 3 innate lymphoid cells by nongastric Helicobacter species. Proceedings of the National Academy of Sciences of the United States of America. 2019 Dec 3;116(49):24760-24769.

Butler J, Packer M, Greene SJ, Fiuzat M, Anker SD, Anstrom KJ, Carson PE, Cooper LB, Fonarow GC, Hernandez AF, Januzzi JL, Jr., Jessup M, Kalyani RR, Kaul S, Kosiborod M, Lindenfeld J, McGuire DK, Sabatine MS, Solomon SD, Teerlink JR, Vaduganathan M, Yancy CW, Stockbridge N, O'Connor CM. Heart Failure End Points in Cardiovascular Outcome Trials of Sodium Glucose Cotransporter 2 Inhibitors in Patients With Type 2 Diabetes Mellitus: A Critical Evaluation of Clinical and Regulatory Issues. Circulation. 2019 Dec 17;140(25):2108-2118.

Coleman RL, Fleming GF, Brady MF, Swisher EM, Steffensen KD, Friedlander M, Okamoto A, Moore KN, Efrat Ben-Baruch N, Werner TL, Cloven NG, Oaknin A, DiSilvestro PA, Morgan MA, Nam JH, Leath CA, 3rd, Nicum S, Hagemann AR, Littell RD, Cella D, Baron-Hay S, Garcia-Donas J, Mizuno M, Bell-McGuinn K, Sullivan DM, Bach BA, Bhattacharya S, Ratajczak CK, Ansell PJ, Dinh MH, Aghajanian C, Bookman MA. Veliparib with First-Line Chemotherapy and as Maintenance Therapy in Ovarian Cancer. New England Journal of Medicine. 2019 Dec 19;381(25):2403-2415.

Cuddy LK, Wani WY, Morella ML, Pitcairn C, Tsutsumi K, Fredriksen K, Justman CJ, Grammatopoulos TN, Belur NR, Zunke F, Subramanian A, Affaneh A, Lansbury PT, Mazzulli JR. Stress-Induced Cellular Clearance Is Mediated by the SNARE Protein ykt6 and Disrupted by alpha-Synuclein. Neuron. 2019 Dec;104(5):869.

Dransfield MT, Voelker H, Bhatt SP, Brenner K, Casaburi R, Come CE, Cooper JAD, Criner GJ, Curtis JL, Han MK, Hatipoglu U, Helgeson ES, Jain VV, Kalhan R, Kaminsky D, Kaner R, Kunisaki KM, Lambert AA, Lammi MR, Lindberg S, Make BJ, Martinez FJ, McEvoy C, Panos RJ, Reed RM, Scanlon PD, Sciurba FC, Smith A, Sriram PS, Stringer WW, Weingarten JA, Wells JM, Westfall E, Lazarus SC, Connett JE. Metoprolol for the Prevention of Acute Exacerbations of COPD. New England Journal of Medicine. 2019 Dec 12;381(24):2304-2314.

Ghosal D, Kim KW, Zheng H, Kaplan M, Truchan HK, Lopez AE, McIntire IE, Vogel JP, Cianciotto NP, Jensen GJ In vivo structure of the Legionella type II secretion system by electron cryotomography. Nature Microbiology. 2019 Dec; 4(12): 2101-2108.

Gur-Cohen S, Yang H, Baksh SC, Miao YX, Levorse J, Kataru RP, Liu XL, de la Cruz-Racelis J, Mehrara BJ, Fuchs E. Stem cell-driven lymphatic remodeling coordinates tissue regeneration. Science. 2019 Dec;366(6470):1218.

Gutruf P, Yin RT, Lee KB, Ausra J, Brennan JA, Qiao Y, Xie ZQ, Peralta R, Talarico O, Murillo A, Chen SW, Leshock JP, Haney CR, Waters EA, Zhang CX, Luan HW, Huang YG, Trachiotis G, Efimov IR, Rogers JA. Wireless, battery-free, fully implantable multimodal and multisite pacemakers for applications in small animal models. Nature Communications. 2019 Dec;10.

Hunt RJ, Granat L, McElroy GS, Ranganathan R, Chandel NS, Bateman JM. Mitochondrial stress causes neuronal dysfunction via an ATF4-dependent increase in L-2-hydroxyglutarate. Journal of Cell Biology. 2019 Dec;218(12):4007-4016.

Kitkungvan D, Yang EY, El Tallawi KC, Nagueh SF, Nabi F, Khan MA, Nguyen DT, Graviss EA, Lawrie GM, Zoghbi WA, Bonow RO, Quinones MA, Shah DJ. Prognostic Implications of Diffuse Interstitial Fibrosis in Asymptomatic Primary Mitral Regurgitation. Circulation. 2019 Dec 17;140(25):2122-2124.

Kollef MH, Novacek M, Kivistik U, Rea-Neto A, Shime N, Martin-Loeches I, Timsit JF, Wunderink RG, Bruno CJ, Huntington JA, Lin G, Yu B, Butterton JR, Rhee EG. Ceftolozane-tazobactam versus meropenem for treatment of nosocomial pneumonia (ASPECT-NP): a randomised, controlled, double-blind, phase 3, non-inferiority trial. Lancet Infectious Diseases. 2019 Dec;19(12):1299-1311.

Lafaille FG, Harschnitz O, Lee YS, Zhang P, Hasek ML, Kerner G, Itan Y, Ewaleifoh O, Rapaport F, Carlile TM, Carter-Timofte ME, Paquet D, Dobbs K, Zimmer B, Gao DX, Rojas-Duran MF, Kwart D, Rattina V, Ciancanelli MJ, McAlpine JL, Lorenzo L, Boucherit S, Rozenberg F, Halwani R, Henry B, Amenzoui N, Alsum Z, Marques L, Church JA, Al-Muhsen S, Tardieu M, Bousfiha AA, Paludan SR, Mogensen TH, Quintana-Murci L, Tessier-Lavigne M, Smith GA, Notarangelo LD, Studer L, Gilbert W, Abel L, Casanova JL, Zhang SY. Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis. Nature Medicine. 2019 Dec;25(12):1873.

Lagae L, Sullivan J, Knupp K, Laux L, Polster T, Nikanorova M, Devinsky O, Cross JH, Guerrini R, Talwar D, Miller I, Farfel G, Galer BS, Gammaitoni A, Mistry A, Morrison G, Lock M, Agarwal A, Lai WW, Ceulemans B, Gill D, Riney K, Scheffer I, Buchhalter J, Carmant L, Connolly M, Nabbout R, Brandt U, Jacobs-LeVan J, Mayer T, Panzer A, Pringsheim M, Stephani U, Wolff M, Battaglia D, Beccaria F, Dana F, Granata T, Romeo A, Striano P, Vigevano F, Gil-Nagel A, San Antonio V, Sanchez-Carpintero R, Desurkar A, Hughes E, Lyer A, Philip S, Zuberi S, Sharp G, Berenson F, Faux L, Marsh E, Nespeca M, Nahouraii R, Paolicdii J, Phillips S, Perry MS, Poduri A, Renfroe B, Saneto R, Shahid A, Smith D, de Menezes MS, Sweney M, Thiele E, Wheless J, Wilfong A, Wirrell E, Zupanc M, Grp FADS. Fenfluramine hydrochloride for the treatment of seizures in Dravet syndrome: a randomised, double-blind, placebo-controlled trial. Lancet. 2019 Dec;394(10216):2243-2254.

Lambo S, Grobner SN, Rausch T, Waszak SM, Schmidt C, Gorthi A, Romero JC, Mauermann M, Brabetz S, Krausert S, Buchhalter I, Koster J, Zwijnenburg DA, Sill M, Hubner JM, Mack N, Schwalm B, Ryzhova M, Hovestadt V, Papillon-Cavanagh S, Chan JA, Landgraf P, Ho B, Milde T, Witt O, Ecker J, Sahm F, Sumerauer D, Ellison DW, Orr BA, Darabi A, Haberler C, Figarella-Branger D, Wesseling P, Schittenhelm J, Remke M, Taylor MD, Gil-da-Costa MJ, Lastowska M, Grajkowska W, Hasselblatt M, Hauser P, Pietsch T, Uro-Coste E, Bourdeaut F, Masliah-Planchon J, Rigau V, Alexandrescu S, Wolf S, Li XN, Schuller U, Snuderl M, Karajannis MA, Giangaspero F, Jabado N, von Deimling A, Jones DTW, Korbel JO, von Hoff K, Lichter P, Huang A, Bishop AJR, Pfister SM, Korshunov A, Kool M. The molecular landscape of ETMR at diagnosis and relapse. Nature. 2019 Dec;576(7786):274.

Mercey O, Levine MS, LoMastro GM, Rostaing P, Brotslaw E, Gomez V, Kumar A, Spassky N, Mitchell BJ, Meunier A, Holland AJ. Massive centriole production can occur in the absence of deuterosomes in multiciliated cells. Nature Cell Biology. 2019 Dec;21(12):1544.

Owen JL, Kibbi N, Worley B, Kelm RC, Wang JV, Barker CA, Behshad R, Bichakjian CK, Bolotin D, Bordeaux JS, Bradshaw SH, Cartee TV, Chandra S, Cho NL, Choi JN, Council ML, Demirci H, Eisen DB, Esmaeli B, Golda N, Huang CC, Ibrahim SF, Jiang SB, Kim J, Kuzel TM, Lai SY, Lawrence N, Lee EH, Leitenberger JJ, Maher IA, Mann MW, Minkis K, Mittal BB, Nehal KS, Neuhaus IM, Ozog DM, Petersen B, Rotemberg V, Samant S, Samie FH, Servaes S, Shields CL, Shin TM, Sobanko JF, Somani AK, Stebbins WG, Thomas JR, Thomas VD, Tse DT, Waldman AH, Wong MK, Xu YG, Yu SS, Zeitouni NC, Ramsay T, Reynolds KA, Poon E, Alam M. Sebaceous carcinoma: evidence-based clinical practice guidelines. Lancet Oncology. 2019 Dec;20(12):E699-E714.

Owens DK, Davidson KW, Krist AH, Barry MJ, Cabana M, Caughey AB, Doubeni CA, Epling JW, Jr., Kubik M, Landefeld CS, Mangione CM, Pbert L, Silverstein M, Simon MA, Tseng CW, Wong JB. Screening for Abdominal Aortic Aneurysm: US Preventive Services Task Force Recommendation Statement. JAMA. 2019 Dec 10;322(22):2211-2218.

Patteson AE, Vahabikashi A, Pogoda K, Adam SA, Mandal K, Kittisopikul M, Sivagurunathan S, Goldman A, Goldman RD, Janmey PA. Vimentin protects cells against nuclear rupture and DNA damage during migration. Journal of Cell Biology. 2019 Dec 2;218(12):4079-4092.

Reeder JT, Xue YG, Franklin D, Deng YJ, Choi J, Prado O, Kim R, Liu C, Hanson J, Ciraldo J, Bandodkar AJ, Krishnan S, Johnson A, Patnaude E, Avila R, Huang YG, Rogers JA. Resettable skin interfaced microfluidic sweat collection devices with chemesthetic hydration feedback. Nature Communications. 2019 Dec;10.

Vahabikashi A, Gelman A, Dong BQ, Gong LH, Cha EDK, Schimmel M, Tamm ER, Perkumas K, Stamer WD, Sun C, Zhang HF, Gong HY, Johnson M. Increased stiffness and flow resistance of the inner wall of Schlemm's canal in glaucomatous human eyes. Proceedings of the National Academy of Sciences of the United States of America. 2019;116(52):26555-26563.

Welsh JD, Hoofnagle MH, Bamezai S, Oxendine M, Lim L, Hall JD, Yang J, Schultz S, Engel JD, Kume T, Oliver G, Jimenez JM, Kahn ML. Hemodynamic regulation of perivalvular endothelial gene expression prevents deep venous thrombosis. Journal of Clinical Investigation. 2019 Dec;129(12):5489-5500.

Younossi ZM, Ratziu V, Loomba R, Rinella M, Anstee QM, Goodman Z, Bedossa P, Geier A, Beckebaum S, Newsome PN, Sheridan D, Sheikh MY, Trotter J, Knapple W, Lawitz E, Abdelmalek MF, Kowdley KV, Montano-Loza AJ, Boursier J, Mathurin P, Bugianesi E, Mazzella G, Olveira A, Cortez-Pinto H, Graupera I, Orr D, Gluud LL, Dufour JF, Shapiro D, Campagna J, Zaru L, MacConell L, Shringarpure R, Harrison S, Sanyal AJ, Investigators RS. Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial. Lancet. 2019 Dec;394(10215):2184-2196.

Ysselstein D, Nguyen M, Young TJ, Severino A, Schwake M, Merchant K, Krainc D. LRRK2 kinase activity regulates lysosomal glucocerebrosidase in neurons derived from Parkinson's disease patients. Nature Communications. 2019 Dec;10.

Zanatta G, Sula A, Miles AJ, Ng LCT, Torella R, Pryde DC, DeCaen PG, Wallace BA. Valproic acid interactions with the NavMs voltage-gated sodium channel. Proceedings of the National Academy of Sciences of the United States of America. 2019;116(52):26549-26554.

Agarwal N, McQuarrie K, Bjartell A, Chowdhury S, Gomes A, Chung BH, Ozguroglu M, Soto AJ, Merseburger AS, Uemura H, Ye DW, Given R, Cella D, Basch E, Miladinovic B, Dearden L, Deprince K, Naini V, Lopez-Gitlitz A, Chi KN, Investigators T. Health-related quality of life after apalutamide treatment in patients with metastatic castration-sensitive prostate cancer (TITAN): a randomised, placebo-controlled, phase 3 study. Lancet Oncology. 2019 Nov;20(11):1518-1530.

Bueno MJ, Jimenez-Renard V, Samino S, Capellades J, Junza A, Lopez-Rodriguez ML, Garcia-Carceles J, Lopez-Fabuel I, Bolanos JP, Chandel NS, Yanes O, Colomer R, Quintela-Fandino M. Essentiality of fatty acid synthase in the 2D to anchorage-independent growth transition in transforming cells. Nature Communications. 2019 Nov;10:18.

Chun E, Lavoie S, Fonseca-Pereira D, Bae S, Michaud M, Hoveyda HR, Fraser GL, Comeau CAG, Glickman JN, Fuller MH, Layden BT, Garrett WS. Metabolite-Sensing Receptor Ffar2 Regulates Colonic Group 3 Innate Lymphoid Cells and Gut Immunity. Immunity. 2019 Nov;51(5):871

Coffey EBJ, Nicol T, White-Schwoch T, Chandrasekaran B, Krizman J, Skoe E, Zatorre RJ, Kraus N. Evolving perspectives on the sources of the frequency-following response. Nature Communications. 2019 Nov;10:10.

Demonbreun AR, Fallon KS, Oosterbaan CC, Bogdanovic E, Warner JL, Sell JJ, Page PG, Quattrocelli M, Barefield DY, McNally EM. Recombinant annexin A6 promotes membrane repair and protects against muscle injury. Journal of Clinical Investigation. 2019 Nov;129(11):4657-4670.

Deng F, Sharma I, Dai YB, Yang M, Kanwar YS. Myo-inositol oxygenase expression profile modulates pathogenic ferroptosis in the renal proximal tubule. Journal of Clinical Investigation. 2019 Nov;129(11):5033-5049.

Han HY, Jain AD, Truica MI, Izquierdo-Ferrer J, Anker JF, Lysy B, Sagar V, Luan Y, Chalmers ZR, Unno K, Mok H, Vatapalli R, Yoo YA, Rodriguez Y, Kandela I, Parker JB, Chakravarti D, Mishra RK, Schiltz GE, Abdulkadir SA. Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy. Cancer Cell. 2019 Nov;36(5):483.

He C, Danes JM, Hart PC, Zhu Y, Huang Y, de Abreu AL, O'Brien J, Mathison AJ, Tang B, Frasor JM, Wakefield LM, Ganini D, Stauder E, Zielonka J, Gantner BN, Urrutia RA, Gius D, Bonini MG. SOD2 acetylation on lysine 68 promotes stem cell reprogramming in breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 2019 Nov 19;116(47):23534-23541.

He Q, Arroyo ED, Smukowski SN, Xu J, Piochon C, Savas JN, Portera-Cailliau C, Contractor A. Critical period inhibition of NKCC1 rectifies synapse plasticity in the somatosensory cortex and restores adult tactile response maps in fragile X mice. Molecular Psychiatry. 2019 Nov;24(11):1732-1747.

Jibril L, Chen PC, Hu JT, Odom TW, Mirkin CA. Massively Parallel Nanoparticle Synthesis in Anisotropic Nanoreactors. Acs Nano. 2019 Nov;13(11):12408-12414.

Kaplan RM, Koehler J, Ziegler PD, Sarkar S, Zweibel S, Passman RS. Stroke Risk as a Function of Atrial Fibrillation Duration and CHA(2)DS(2)-VASc Score. Circulation. 2019 Nov;140(20):1639-1646.

Kightlinger W, Duncker KE, Ramesh A, Thames AH, Natarajan A, Stark JC, Yang A, Lin L, Mrksich M, DeLisa MP, Jewett MC. A cell-free biosynthesis platform for modular construction of protein glycosylation pathways. Nat Communications. 2019 Nov 27;10(1):5404.

Notomi S, Ishihara K, Efstathiou NE, Lee JJ, Hisatomi T, Tachibana T, Konstantinou EK, Ueta T, Murakami Y, Maidana DE, Ikeda Y, Kume S, Terasaki H, Sonoda S, Blanz J, Young L, Sakamoto T, Sonoda KH, Saftig P, Ishibashi T, Miller JW, Kroemer G, Vavvas DG. Genetic LAMP2 deficiency accelerates the age-associated formation of basal laminar deposits in the retina. Proceedings of the National Academy of Sciences of the United States of America. 2019 Nov 19;116(47):23724-23734.

Parker WF, Anderson AS, Gibbons RD, Garrity ER, Ross LF, Huang ES, Churpek MM. Association of Transplant Center With Survival Benefit Among Adults Undergoing Heart Transplant in the United States. JAMA-Journal of the American Medical Association. 2019 Nov;322(18):1789-1798.

Pawlak JB, Balint L, Lim L, Ma WS, Davis RB, Benyo Z, Soares MJ, Oliver G, Kahn ML, Jakus Z, Caron KM. Lymphatic mimicry in maternal endothelial cells promotes placental spiral artery remodeling. Journal of Clinical Investigation. 2019 Nov;129(11):4912-4921.

Quagliarini F, Mir AA, Balazs K, Wierer M, Dyar KA, Jouffe C, Makris K, Hawe J, Heinig M, Filipp FV, Barish GD, Uhlenhaut NH. Cistromic Reprogramming of the Diurnal Glucocorticoid Hormone Response by High-Fat Diet. Molecular Cell. 2019 Nov;76(4):531.

Seitzman BA, Gratton C, Laumann TO, Gordon EM, Adeyemo B, Dworetsky A, Kraus BT, Gilmore AW, Berg JJ, Ortega M, Nguyen A, Greene DJ, McDermott KB, Nelson SM, Lessov-Schlaggar CN, Schlaggar BL, Dosenbach NUF, Petersen SE. Trait-like variants in human functional brain networks. Proceedings of the National Academy of Sciences of the United States of America. 2019 Nov 5;116(45):22851-22861.

Sullivan DP, Dalal PJ, Jaulin F, Sacks DB, Kreitzer G, Muller WA. Endothelial IQGAP1 regulates leukocyte transmigration by directing the LBRC to the site of diapedesis. Journal of Experimental Medicine. 2019 Nov;216(11):2582-2601.

Visvanathan K, Fabian CJ, Bantug E, Brewster AM, Davidson NE, DeCensi A, Floyd JD, Garber JE, Hofstatter EW, Khan SA, Katapodi MC, Pruthi S, Raab R, Runowicz CD, Somerfield MR. Use of Endocrine Therapy for Breast Cancer Risk Reduction: ASCO Clinical Practice Guideline Update. Journal of Clinical Oncology. 2019 Nov 20;37(33):3152-3165.

Yu XG, Xie ZQ, Yu Y, Lee J, Vazquez-Guardado A, Luan HW, Ruben J, Ning X, Akhtar A, Li DF, Ji BW, Liu YM, Sun RJ, Cao JY, Huo QZ, Zhong YS, Lee C, Kim S, Gutruf P, Zhang CX, Xue YG, Guo QL, Chempakasseril A, Tian PL, Lu W, Jeong J, Yu Y, Cornman J, Tan C, Kirn B, Lee K, Feng X, Huang YG, Rogers JA. Skin-integrated wireless haptic interfaces for virtual and augmented reality. Nature. 2019 Nov;575(7783):473.

Zhang P, Miska J, Lee-Chang C, Rashidi A, Panek WK, An S, Zannikou M, Lopez-Rosas A, Han Y, Xiao T, Pituch KC, Kanojia D, Balyasnikova IV, Lesniak MS. Therapeutic targeting of tumor-associated myeloid cells synergizes with radiation therapy for glioblastoma. Proceedings of the National Academy of Sciences of the United States of America. 2019 Nov 19;116(47):23714-23723.

Burbulla LF, Jeon S, Zheng JB, Song PP, Silverman RB, Krainc D. A modulator of wild-type glucocerebrosidase improves pathogenic phenotypes in dopaminergic neuronal models of Parkinson's disease. Science Translational Medicine. 2019 Oct;11(514):11.

Clark DW, Okada Y, Moore KHS, et al. (including Cornelis M). Associations of autozygosity with a broad range of human phenotypes. Nat Communications. 2019 Oct 31;10(1):4957.

Dix DB, Fernandez CV, Chi YY, Mullen EA, Geller JI, Gratias EJ, Khanna G, Kalapurakal JA, Perlman EJ, Seibel NL, Ehrlich PF, Malogolowkin M, Anderson J, Gastier-Foster J, Shamberger RC, Kim Y, Grundy PE, Dome JS. Augmentation of Therapy for Combined Loss of Heterozygosity 1p and 16q in Favorable Histology Wilms Tumor: A Children's Oncology Group AREN0532 and AREN0533 Study Report. Journal of Clinical Oncology. 2019 Oct 20;37(30):2769-2777.

Giuliano M, Schettini F, Rognoni C, Milani M, Jerusalem G, Bachelot T, De Laurentiis M, Thomas G, De Placido P, Arpino G, De Placido S, Cristofanilli M, Giordano A, Puglisi F, Pistilli B, Prat A, Del Mastro L, Venturini S, Generali D. Endocrine treatment versus chemotherapy in postmenopausal women with hormone receptor-positive, HER2-negative, metastatic breast cancer: a systematic review and network meta-analysis. Lancet Oncology. 2019 Oct;20(10):1360-1369.

Henrichs J, Verfaille V, Jellema P, Viester L, Pajkrt E, Wilschut J, van der Horst HE, Franx A, de Jonge A, van Baar AL, Bais JMJ, Bonsel GJ, Bosmans JE, van Dillen J, van Duijnhoven NTL, Grobman WA, Groen H, Hukkelhoven C, Klomp T, Kok M, de Kroon ML, Kruijt M, Kwee A, Ledda S, Lafeber HN, van Lith JMM, Mol B, Molewijk B, Nieuwenhuijze M, Oei G, Oudejans C, Paarlberg KM, Papageorghiou AT, Reddy UM, De Reu P, Rijnders M, de Roon-Immerzeel A, Scheele C, Scherjon SA, Snijders R, Spaanderman ME, Teunissen PW, Torij HW, Vrijkotte TG, Westerneng M, Zeeman KC, Zhang JJ, Grp IS. Effectiveness of routine third trimester ultrasonography to reduce adverse perinatal outcomes in low risk pregnancy (the IRIS study): nationwide, pragmatic, multicentre, stepped wedge cluster randomised trial. BMJ-British Medical Journal. 2019 Oct;367:13.

Hu YY, Ellis RJ, Hewitt DB, Yang AD, Cheung EO, Moskowitz JT, Potts JR, 3rd, Buyske J, Hoyt DB, Nasca TJ, Bilimoria KY. Discrimination, Abuse, Harassment, and Burnout in Surgical Residency Training. New England Journal of Medicine. 2019 Oct 31;381(18):1741-1752.

Kaufmann T, van der Meer D, Doan NT, Schwarz E, Lund MJ, Agartz I, Alnaes D, Barch DM, Baur-Streubel R, Bertolino A, Bettella F, Beyer MK, Boen E, Borgwardt S, Brandt CL, Buitelaar J, Celius EG, Cervenka S, Conzelmann A, Cordova-Palomera A, Dale AM, de Quervain DJF, Carlo P, Djurovic S, Dorum ES, Eisenacher S, Elvsashagen T, Espeseth T, Fatouros-Bergman H, Flyckt L, Franke B, Frei O, Haatveit B, Haberg AK, Harbo HF, Hartman CA, Heslenfeld D, Hoekstra PJ, Hogestol EA, Jernigan TL, Jonassen R, Jonsson EG, Kirsch P, Kloszewska I, Kolskar KK, Landro NI, Hellard S, Lesch KP, Lovestone S, Lundervold A, Lundervold AJ, Maglanoc LA, Malt UF, Mecocci P, Melle I, Meyer-Lindenberg A, Moberget T, Norbom LB, Nordvik JE, Nyberg L, Oosterlaan J, Papalino M, Papassotiropoulos A, Pauli P, Pergola G, Persson K, Richard G, Rokicki J, Sanders AM, Selbaek G, Shadrin AA, Smeland OB, Soininen H, Sowa P, Steen VM, Tsolaki M, Ulrichsen KM, Vellas B, Wang L, Westman E, Ziegler GC, Zink M, Andreassen OA, Westlye LT. Common brain disorders are associated with heritable patterns of apparent aging of the brain. Nature Neuroscience. 2019 Oct;22(10):1617-1623.

Kim J, Hu C, Moufawad El Achkar C, Black LE, Douville J, Larson A, Pendergast MK, Goldkind SF, Lee EA, Kuniholm A, Soucy A, Vaze J, Belur NR, Fredriksen K, Stojkovska I, Tsytsykova A, Armant M, DiDonato RL, Choi J, Cornelissen L, Pereira LM, Augustine EF, Genetti CA, Dies K, Barton B, Williams L, Goodlett BD, Riley BL, Pasternak A, Berry ER, Pflock KA, Chu S, Reed C, Tyndall K, Agrawal PB, Beggs AH, Grant PE, Urion DK, Snyder RO, Waisbren SE, Poduri A, Park PJ, Patterson A, Biffi A, Mazzulli JR, Bodamer O, Berde CB, Yu TW. Patient-Customized Oligonucleotide Therapy for a Rare Genetic Disease. New England Journal of Medicine. 2019 Oct 24;381(17):1644-1652.

Manski CF, Tambur AR, Gmeiner M. Predicting kidney transplant outcomes with partial knowledge of HLA mismatch. Proceedings of the National Academy of Sciences of the United States of America. 2019 Oct 8;116(41):20339-20345.

Nam KW, Park SS, Dos Reis R, Dravid VP, Kim H, Mirkin CA, Stoddart JF. Conductive 2D metal-organic framework for high-performance cathodes in aqueous rechargeable zinc batteries. Nat Communications. 2019 Oct 30;10(1):4948.

Nassif ME, Windsor SL, Tang F, Khariton Y, Husain M, Inzucchi SE, Mc-Guire DK, Pitt B, Scirica BM, Austin B, Drazner MH, Fong MW, Givertz MM, Gordon RA, Jermyn R, Katz SD, Lamba S, Lanfear DE, LaRue SJ, Lindenfeld J, Malone M, Margulies K, Mentz RJ, Mutharasan RK, Pursley M, Umpierrez G, Kosiborod M. Dapagliflozin Effects on Biomarkers, Symptoms, and Functional Status in Patients With Heart Failure With Reduced Ejection Fraction: The DEFINE-HF Trial. Circulation. 2019 Oct 29;140(18):1463-1476.

Phan HP, Zhong Y, Nguyen TK, Park Y, Dinh T, Song E, Vadivelu RK, Masud MK, Li J, Shiddiky MJA, Dao D, Yamauchi Y, Rogers JA, Nguyen NT. Long-Lived, Transferred Crystalline Silicon Carbide Nanomembranes for Implantable Flexible Electronics. ACS Nano. 2019 Oct 22;13(10):11572-11581.

Ramachandran K, Senagolage MD, Sommars MA, Futtner CR, Omura Y, Allred AL, Barish GD. Dynamic enhancers control skeletal muscle identity and reprogramming. PLoS Biology. 2019 Oct;17(10):e3000467.

Solomon SD, McMurray JJV, Anand IS, Ge J, Lam CSP, Maggioni AP, Martinez F, Packer M, Pfeffer MA, Pieske B, Redfield MM, Rouleau JL, van Veldhuisen DJ, Zannad F, Zile MR, Desai AS, Claggett B, Jhund PS, Boytsov SA, Comin-Colet J, Cleland J, Dungen HD, Goncalvesova E, Katova T, Kerr Saraiva JF, Lelonek M, Merkely B, Senni M, Shah SJ, Zhou J, Rizkala AR, Gong J, Shi VC, Lefkowitz MP. Angiotensin-Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction. New England Journal of Medicine. 2019 Oct 24;381(17):1609-1620.

Walker DA, Hedrick JL, Mirkin CA. Rapid, large-volume, thermally controlled 3D printing using a mobile liquid interface. Science. 2019 Oct;366(6463):360.

Won SM, Wang H, Kim BH, Lee K, Jang H, Kwon K, Han M, Crawford KE, Li H, Lee Y, Yuan X, Kim SB, Oh YS, Jang WJ, Lee JY, Han S, Kim J, Wang X, Xie Z, Zhang Y, Huang Y, Rogers JA. Multimodal Sensing with a Three-Dimensional Piezoresistive Structure. ACS Nano. 2019 Oct 22;13(10):10972-10979.

Zhang Y, Castro DC, Han Y, Wu YX, Guo HX, Weng ZY, Xue YG, Ausra J, Wang XJ, Li R, Wu GF, Vazquez-Guardado A, Xie YW, Xie ZQ, Ostojich D, Peng DS, Sun RJ, Wang BB, Yu Y, Leshock JP, Qu SB, Su CJ, Shen W, Hang T, Banks A, Huang YG, Radulovic J, Gutruf P, Bruchas MR, Rogers JA. Battery-free, lightweight, injectable microsystem for in vivo wireless pharmacology and optogenetics. Proceedings of the National Academy of Sciences of the United States of America. 2019 Oct;116(43):21427-21437.

Arnett DK, Blumenthal RS, Albert MA, Buroker AB, Goldberger ZD, Hahn EJ, Himmelfarb CD, Khera A, Lloyd-Jones D, McEvoy JW, Michos ED, Miedema MD, Munoz D, Smith SC, Virani SS, Williams KA, Yeboah J, Ziaeian B. 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2019 Sep;140(11):E563-E595.

Berger A, Brady NJ, Bareja R, Robinson B, Conteduca V, Augello MA, Ruca L, Ahmed A, Dardenne E, Lu XD, Hwang I, Bagadion AM, Sboner A, Elemento O, Paik J, Yu JD, Barbieri CE, Dephoure N, Beltran H, Rickman DS. N-Myc mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer. Journal of Clinical Investigation. 2019 Sep;129(9):3924-3940.

Cedernaes J, Waldeck N, Bass J. Neurogenetic basis for circadian regulation of metabolism by the hypothalamus. Genes & Development. 2019 Sep;33(17-18):1136-1158.

Gal-Oz ST, Maier B, Yoshida H, Seddu K, Elbaz N, Czysz C, Zuk O, Stranger BE, Ner-Gaon H, Shay T. ImmGen report: sexual dimorphism in the immune system transcriptome. Nature Communications. 2019 Sep;10:14.

Heywood I, Camilo F, Cotton WD, Yusef-Zadeh F, et al. Inflation of 430-parsec bipolar radio bubbles in the Galactic Centre by an energetic event. Nature. 2019 Sep;573(7773):235.

Huang LL, Liu M, Lin HX, Xu YB, Wu JS, Dravid VP, Wolverton C, Mirkin CA. Shape regulation of high-index facet nanoparticles by dealloying. Science. 2019 Sep;365(6458):1159.

Labbe DP, Zadra G, Yang M, Reyes JM, Lin CY, Cacciatore S, Ebot EM, Creech AL, Giunchi F, Fiorentino M, Elfandy H, Syamala S, Karoly ED, Alshalalfa M, Erho N, Ross A, Schaeffer EM, Gibb EA, Takhar M, Den RB, Lehrer J, Karnes RJ, Freedland SJ, Davicioni E, Spratt DE, Ellis L, Jaffe JD, Amico AVD, Kantoff PW, Bradner JE, Mucci LA, Chavarro JE, Loda M, Brown M. High-fat diet fuels prostate cancer progression by rewiring the metabolome and amplifying the MYC program. Nature Communications. 2019 Sep;10:14.

Leenay RT, Aghazadeh A, Hiatt J, Tse D, Roth TL, Apathy R, Shifrut E, Hultquist JF, Krogan N, Wu Z, Cirolia G, Canaj H, Leonetti MD, Marson A, May AP, Zou J. Large dataset enables prediction of repair after CRISPR-Cas9 editing in primary T cells. Nature Biotechnology. 2019 Sep;37(9):1034-1037.

Li H, Dong BQ, Zhang X, Shu X, Chen XF, Hai RH, Czaplewski DA, Zhang HF, Sun C. Disposable ultrasound-sensing chronic cranial window by soft nanoimprinting lithography. Nature Communications. 2019 Sep;10:9.

Liu XP, Helenius D, Skotte L, et al. (including Hayes MG, Scholtens DM). Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration. Nature Communications. 2019 Sep;10:13.

McEvoy JW, Ziaeian B, Yeboah J, Williams KA, Virani SS, Smith SC, Munoz D, Miedema MD, Michos ED, Arnett DK, Lloyd-Jones D, Khera A, Himmelfarb CD, Hahn EJ, Goldberger ZD, Buroker AB, Albert MA, Blumenthal RS. 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2019 Sep;140(11):E596-E646.

Muss HB, Polley MYC, Berry DA, Liu HS, Cirrincione CT, Theodoulou M, Mauer AM, Kornblith AB, Partridge AH, Dressler LG, Cohen HJ, Kartcheske PA, Perez EA, Wolff AC, Gralow JR, Burstein HJ, Mahmood AA, Sutton LM, Magrinat G, Parker BA, Hart RD, Grenier D, Hurria A, Jatoi A, Norton L, Hudis CA, Winer EP, Carey L. Randomized Trial of Standard Adjuvant Chemotherapy Regimens Versus Capecitabine in Older Women With Early Breast Cancer: 10-Year Update of the CALGB 49907 Trial. Journal of Clinical Oncology. 2019 Sep;37(26):2338.

Nam HH, Ison MG. Respiratory syncytial virus infection in adults. BMJ-British Medical Journal. 2019 Sep;366:17.

Owens DK, Davidson KW, Krist AH, Barry MJ, Cabana M, Caughey AB, Doubeni CA, Epling JW, Jr., Kubik M, Landefeld CS, Mangione CM, Pbert L, Silverstein M, Simon MA, Tseng CW, Wong JB. Screening for Asymptomatic Bacteriuria in Adults: US Preventive Services Task Force Recommendation Statement. JAMA. 2019 Sep 24;322(12):1188-1194.

Sang YZ, Li YX, Zhang YW, Alvarez AA, Yu B, Zhang WW, Hu B, Cheng SY, Feng HZ. CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity. Nature Communications. 2019 Sep;10:17.

Shao S, Tsoi LC, Sarkar MK, Xing X, Xue K, Uppala R, Berthier CC, Zeng C, Patrick M, Billi AC, Fullmer J, Beamer MA, Perez-White B, Getsios S, Schuler A, Voorhees JJ, Choi S, Harms P, Kahlenberg JM, Gudjonsson JE. IFN-gamma enhances cell-mediated cytotoxicity against keratinocytes via JAK2/STAT1 in lichen planus. Science Translational Medicine. 2019 Sep 25;11(511).

Treat-Jacobson D, McDermott MM, Beckman JA, Burt MA, Creager MA, Ehrman JK, Gardner AW, Mays RJ, Regensteiner JG, Salisbury DL, Schorr EN, Walsh ME, Amer Heart Assoc Council P, Council Cardiovasc Stroke N, Council Epidemiology P, Council Lifestyle Cardiometab H. Implementation of Supervised Exercise Therapy for Patients With Symptomatic Peripheral Artery Disease: A Science Advisory From the American Heart Association. Circulation. 2019 Sep;140(13):E700-E710.

Wechsler ME, Szefler SJ, Ortega VE, et al. (including Smith LJ). Step-Up Therapy in Black Children and Adults with Poorly Controlled Asthma. New England Journal of Medicine. 2019 Sep 26;381(13):1227-1239.

Yeager DS, Hanselman P, Walton GM, Murray JS, Crosnoe R, Muller C, Tipton E, Schneider B, Hulleman CS, Hinojosa CP, Paunesku D, Romero C, Flint K, Roberts A, Trott J, Iachan R, Buontempo J, Yang SM, Carvalho CM, Hahn PR, Gopalan M, Mhatre P, Ferguson R, Duckworth AL, Dweck CS. A national experiment reveals where a growth mindset improves achievement. Nature. 2019 Sep;573(7774):364.

Agha G, Mendelson MM, Ward-Caviness CK, Joehanes R, Huan T, Gondalia R, Salfati E, Brody JA, Fiorito G, Bressler J, Chen BH, Ligthart S, Guarrera S, Colicino E, Just AC, Wahl S, Gieger C, Vandiver AR, Tanaka T, Hernandez DG, Pilling LC, Singleton AB, Sacerdote C, Krogh V, Panico S, Tumino R, Li Y, Zhang G, Stewart JD, Floyd JS, Wiggins KL, Rotter JI, Multhaup M, Bakulski K, Horvath S, Tsao PS, Absher DM, Vokonas P, Hirschhorn J, Fallin MD, Liu C, Bandinelli S, Boerwinkle E, Dehghan A, Schwartz JD, Psaty BM, Feinberg AP, Hou L, Ferrucci L, Sotoodehnia N, Matullo G, Peters A, Fornage M, Assimes TL, Whitsel EA, Levy D, Baccarelli AA. Blood Leukocyte DNA Methylation Predicts Risk of Future Myocardial Infarction and Coronary Heart Disease. Circulation. 2019 Aug 20;140(8):645-657.

Cassidy JJ, Bernasekz SM, Bakker R, Giri R, Pelaez N, Eder B, Bobrowska A, Bagheri N, Amaral LAN, Carthew RW. Repressive Gene Regulation Synchronizes Development with Cellular Metabolism. Cell. 2019 Aug;178(4):980.

Cederroth CR, Albrecht U, Bass J, Brown SA, Dyhrfjeld-Johnsen J, Gachon F, Green CB, Hastings MH, Helfrich-Forster C, Hogenesch JB, Levi F, Loudon A, Lundkvist GB, Meijer JH, Rosbash M, Takahashi JS, Young M, Canlon B. Medicine in the Fourth Dimension. Cell Metabolism. 2019 Aug;30(2):238-250.

Chiocca EA, Yu JS, Lukas RV, Solomon IH, Ligon KL, Nakashima H, Triggs DA, Reardon DA, Wen P, Stopa BM, Naik A, Rudnick J, Hu JL, Kumthekar P, Yamini B, Buck JY, Demars N, Barrett JA, Gelb AB, Zhou J, Lebel F, Cooper LJN. Regulatable interleukin-12 gene therapy in patients with recurrent high-grade glioma: Results of a phase 1 trial. Science Translational Medicine. 2019 Aug;11(505):13.

Cohen E, Rodean J, Diong C, Hall M, Freedman SB, Aronson PL, Simon HK, Marin JR, Samuels-Kalow M, Alpern ER, Morse RB, Shah SS, Peltz A, Neuman MI. Low-Value Diagnostic Imaging Use in the Pediatric Emergency Department in the United States and Canada. JAMA Pediatrics. 2019 Aug;173(8):10.

Cunningham RM, Carter PM, Ranney ML, Walton M, Zeoli AM, Alpern ER, Branas C, Beidas RS, Ehrlich PF, Goyal MK, Goldstick JE, Hemenway D, Hargarten SW, King CA, Massey L, Ngo Q, Pizarro J, Prosser L, Rowhani-Rahbar A, Rivara F, Rupp LA, Sigel E, Savolainen J, Zimmerman MA. Prevention of Firearm Injuries Among Children and Adolescents: Consensus-Driven Research Agenda from the Firearm Safety Among Children and Teens (FACTS) Consortium. JAMA Pediatrics. 2019 Aug;173(8):780-789.

Federman AD, O'Conor R, Mindlis I, Hoy-Rosas J, Hauser D, Lurio J, Shroff N, Lopez R, Erblich J, Wolf MS, Wisnivesky JP. Effect of a Self-management Support Intervention on Asthma Outcomes in Older Adults: The SAMBA Study Randomized Clinical Trial. JAMA Internal Medicine. 2019 Aug;179(8):1113-1121.

Ferguson MA, Lim C, Cooke D, Darby RR, Wu O, Rost NS, Corbetta M, Grafman J, Fox MD. A human memory circuit derived from brain lesions causing amnesia. Nature Communications. 2019 Aug;10:9.

Heybrock S, Kanerva K, Meng Y, Ing C, Liang A, Xiong ZJ, Weng XL, Kim YA, Collins R, Trimble W, Pomes R, Prive GG, Annaert W, Schwake M, Heeren J, Lullmann-Rauch R, Grinstein S, Ikonen E, Saftig P, Neculai D. Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export. Nature Communications. 2019 Aug;10:12.

Hu J, Li Y, Hao Y, Zheng T, Gupta SK, Parada GA, Wu H, Lin S, Wang S, Zhao X, Goldman RD, Cai S, Guo M. High stretchability, strength, and toughness of living cells enabled by hyperelastic vimentin intermediate filaments. Proceedings of the National Academy of Sciences of the United States of America. 2019 Aug 27;116(35):17175-17180.

Johnson DB, McDonnell WJ, Gonzalez-Ericsson PI, Al-Rohil RN, Mobley BC, Salem JE, Wang DY, Sanchez V, Wang Y, Chastain CA, Barker K, Liang Y, Warren S, Beechem JM, Menzies AM, Tio M, Long GV, Cohen JV, Guidon AC, O'Hare M, Chandra S, Chowdhary A, Lebrun-Vignes B, Goldinger SM, Rushing EJ, Buchbinder EI, Mallal SA, Shi CJ, Xu YM, Moslehi JJ, Sanders ME, Sosman JA, Balko JM. A case report of clonal EBV-like memory CD4(+) T cell activation in fatal checkpoint inhibitor-induced encephalitis. Nature Medicine. 2019 Aug;25(8):1243.

Karbasforoushan H, Cohen-Adad J, Dewald JPA. Brainstem and spinal cord MRI identifies altered sensorimotor pathways post-stroke. Nature Communications. 2019 Aug;10:7.

Kofuji S, Hirayama A, Eberhardt AO, Kawaguchi R, Sugiura Y, Sampetrean O, Ikeda Y, Warren M, Sakamoto N, Kitahara S, Yoshino H, Yamashita D, Sumita K, Wolfe K, Lange L, Ikeda S, Shimada H, Minami N, Malhotra A, Morioka S, Ban YL, Asano M, Flanary VL, Ramkissoon A, Chow LML, Kiyokawa J, Mashimo T, Lucey G, Mareninov S, Ozawa T, Onishi N, Okumura K, Terakawa J, Daikoku T, Wise-Draper T, Majd N, Kofuji K, Sasaki M, Mori M, Kanemura Y, Smith EP, Anastasiou D, Wakimoto H, Holland EC, Yong WH, Horbinski C, Nakano I, DeBerardinis RJ, Bachoo RM, Mischel PS, Yasui W, Suematsu M, Saya H, Soga T, Grummt I, Bierhoff H, Sasaki AT. IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma. Nature Cell Biology. 2019 Aug;21(8):1003.

Labuhn M, Perkins K, Matzk S, Varghese L, Garnett C, Papaemmanuil E, Metzner M, Kennedy A, Amstislayskiy V, Risch T, Bhayadia R, Samulowski D, Hernandez DC, Stoilova B, Lotchkova V, Oppermann U, Scheer C, Yoshida K, Schwarzer A, Taub J, Crispino JD, Weiss MJ, Hayashi A, Taga T, Ito E, Ogawa S, Reinhardt D, Yaspo ML, Campbell PJ, Roberts I, Constantinescu S, Vyas P, Heckl D, Klusmann JH. Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome. Cancer Cell. 2019 Aug;36(2):123.

Manolio TA, Rowley R, Williams MS, Roden D, Ginsburg GS, Bult C, Chisholm RL, Deverka PA, McLeod HL, Mensah GA, Relling MV, Rodriguez LL, Tamburro C, Green ED. Opportunities, resources, and techniques for implementing genomics in clinical care. Lancet. 2019 Aug;394(10197):511-520.

Merkow RP, Yang AD, Pavey E, Song MW, Chung JW, Bentrem DJ, Bilimoria KY. Comparison of Hospitals Affiliated With PPS-Exempt Cancer Centers, Other Hospitals Affiliated With NCI-Designated Cancer Centers, and Other Hospitals That Provide Cancer Care. JAMA Internal Medicine. 2019 Aug;179(8):1043-1051.

Owens DK, Davidson KW, Krist AH, Barry MJ, Cabana M, Caughey AB, Curry SJ, Doubeni CA, Epling JW, Kubik M, Landefeld CS, Mangione CM, Pbert L, Silverstein M, Simon MA, Tseng CW, Wong JB, Force USPST. Screening for Pancreatic Cancer: US Preventive Services Task Force Reaffirmation Recommendation Statement. JAMA-Journal of the American Medical Association. 2019 Aug;322(5):438-444.

Owens DK, Davidson KW, Krist AH, Barry MJ, Cabana M, Caughey AB, Doubeni CA, Epling JW, Jr., Kubik M, Landefeld CS, Mangione CM, Pbert L, Silverstein M, Simon MA, Tseng CW, Wong JB. Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer: US Preventive Services Task Force Recommendation Statement. JAMA-Journal of the American Medical Association. 2019 Aug 20;322(7):652-665.

Panza JA, Ellis AM, Al-Khalidi HR, Holly TA, Berman DS, Oh JK, Pohost GM, Sopko G, Chrzanowski L, Mark DB, Kukulski T, Favaloro LE, Maurer G, Farsky PS, Tan RS, Asch FM, Velazquez EJ, Rouleau JL, Lee KL, Bonow RO. Myocardial Viability and Long-Term Outcomes in Ischemic Cardiomyopathy. New England Journal of Medicine. 2019 Aug;381(8):739-748.

Pittas AG, Dawson-Hughes B, Sheehan P, Ware JH, Knowler WC, Aroda VR, Brodsky I, Ceglia L, Chadha C, Chatterjee R, Desouza C, Dolor R, Foreyt J, Fuss P, Ghazi A, Hsia DS, Johnson KC, Kashyap SR, Kim S, LeBlanc ES, Lewis MR, Liao E, Neff LM, Nelson J, O'Neil P, Park J, Peters A, Phillips LS, Pratley R, Raskin P, Rasouli N, Robbins D, Rosen C, Vickery EM, Staten M, Grp DdR. Vitamin D Supplementation and Prevention of Type 2 Diabetes. New England Journal of Medicine. 2019 Aug;381(6):520-530.

Ricard N, Scott RP, Booth CJ, Velazquez H, Cilfone NA, Baylon JL, Gulcher JR, Quaggin SE, Chittenden TW, Simons M. Endothelial ERK1/2 signaling maintains integrity of the quiescent endothelium. Journal of Experimental Medicine. 2019 Aug 5;216(8):1874-1890.

Roder-DeWan S, Gage AD, Hirschhorn LR, Twum-Danso NAY, Liljestrand J, Asante-Shongwe K, Rodriguez V, Yahya T, Kruk ME. Expectations of healthcare quality: A cross-sectional study of internet users in 12 low- and middle-income countries. PLoS Medicine. 2019 Aug;16(8):e1002879.

Ruhl DA, Bomba-Warczak E, Watson ET, Bradberry MM, Peterson TA, Basu T, Frelka A, Evans CS, Briguglio JS, Basta T, Stowell MHB, Savas JN, Roopra A, Pearce RA, Piper RC, Chapman ER. Synaptotagmin 17 controls neurite outgrowth and synaptic physiology via distinct cellular pathways. Nature Communications. 2019 Aug;10:14.

Rychik J, Atz AM, Celermajer DS, Deal BJ, Gatzoulis MA, Gewillig MH, Hsia TY, Hsu DT, Kovacs AH, McCrindle BW, Newburger JW, Pike NA, Rodefeld M, Rosenthal DN, Schumacher KR, Marino BS, Stout K, Veldtman G, Younoszai AK, d'Udekem Y, Amer Heart Assoc Council C, Council Cardiovasc Stroke N. Evaluation and Management of the Child and Adult With Fontan Circulation: A Scientific Statement From the American Heart Association. Circulation. 2019 Aug;140(6):E234-E284.

Schwulst SJ, Son M. Diagnostic Imaging in Pregnant Patients With Suspected Appendicitis. JAMA-Journal of the American Medical Association. 2019 Aug;322(5):455-456.

Singh A, Ramachandran S, Graham ML, Daneshmandi S, Heller D, Suarez-Pinzon WL, Balamurugan AN, Ansite JD, Wilhelm JJ, Yang A, Zhang Y, Palani NP, Abrahante JE, Burlak C, Miller SD, Luo XR, Hering BJ. Long-term tolerance of islet allografts in nonhuman primates induced by apoptotic donor leukocytes. Nature Communications. 2019 Aug;10:16.

Topjian AA, de Caen A, Wainwright MS, Abella BS, Abend NS, Atkins DL, Bembea MM, Fink EL, Guerguerian AM, Haskell SE, Kilgannon JH, Lasa JJ, Hazinski MF, Amer Heart Assoc Emergency C, Amer Heart Assoc Emergency C, Council Cardiopulm Critical C, Council Cardiovasc Stroke N, Council Clinical C, Council Genomic Precision M, Stroke C. Pediatric Post-Cardiac Arrest Care: A Scientific Statement From the American Heart Association. Circulation. 2019 Aug;140(6):E194-E233.

Tunc-Ozcan E, Peng CY, Zhu YW, Dunlop SR, Contractor A, Kessler JA. Activating newborn neurons suppresses depression and anxiety-like behaviors. Nature Communications. 2019 Aug;10:9.

Vachon-Presseau E, Berger SE, Abdullah TB, Griffith JW, Schnitzer TJ, Apkarian AV. Identification of traits and functional connectivity-based neurotraits of chronic pain. PLoS Biology. 2019 Aug;17(8):e3000349.

Wong YC, Peng W, Krainc D. Lysosomal Regulation of Inter-mitochondrial Contact Fate and Motility in Charcot-Marie-Tooth Type 2. Developmental Cell. 2019 Aug;50(3):339.

Bartlett NL, Wilson WH, Jung SH, Hsi ED, Maurer MJ, Pederson LD, Polley MC, Pitcher BN, Cheson BD, Kahl BS, Friedberg JW, Staudt LM, Wagner-Johnston ND, Blum KA, Abramson JS, Reddy NM, Winter JN, Chang JE, Gopal AK, Chadburn A, Mathew S, Fisher RI, Richards KL, Schoder H, Zelenetz AD, Leonard JP. Dose-Adjusted EPOCH-R Compared With R-CHOP as Frontline Therapy for Diffuse Large B-Cell Lymphoma: Clinical Outcomes of the Phase III Intergroup Trial Alliance/CALGB 50303. Journal of Clinical Oncology. 2019 Jul 20;37(21):1790-1799.

Bornstein NM, Saver JL, Diener HC, Gorelick PB, Shuaib A, Solberg Y, Thackeray L, Savic M, Janelidze T, Zarqua N, Yarnitsky D, Molina CA, Imp ACTBI. An injectable implant to stimulate the sphenopalatine ganglion for treatment of acute ischaemic stroke up to 24 h from onset (ImpACT-24B): an international, randomised, double-blind, sham-controlled, pivotal trial. Lancet. 2019 Jul;394(10194):219-229.

Choi J, Troyanovsky RB, Indra I, Mitchell BJ, Troyanovsky SM. Scribble, Erbin, and Lano redundantly regulate epithelial polarity and apical adhesion complex. Journal of Cell Biology. 2019 Jul;218(7):2277-2293.

Donnelly DP, Rawlins CM, DeHart CJ, Fornelli L, Schachner LF, Lin Z, Lippens JL, Aluri KC, Sarin R, Chen B, Lantz C, Jung W, Johnson KR, Koller A, Wolff JJ, Campuzano IDG, Auclair JR, Ivanov AR, Whitelegge JP, Pasa-Tolic L, Chamot-Rooke J, Danis PO, Smith LM, Tsybin YO, Loo JA, Ge Y, Kelleher NL, Agar JN. Best practices and benchmarks for intact protein analysis for top-down mass spectrometry. Nature Methods. 2019 Jul;16(7):587-594.

Feinstein MJ, Hsue PY, Benjamin LA, Bloomfield GS, Currier JS, Freiberg MS, Grinspoon SK, Levin J, Longenecker CT, Post WS, Council Epidemiology P, Council C, Stroke, Council Clin C, Stroke. Characteristics, Prevention, and Management of Cardiovascular Disease in People Living With HIV: A Scientific Statement From the American Heart Association. Circulation. 2019 Jul;140(2):E98-E124.

Galvan DL, Long JY, Green N, Chang BH, Lin JS, Schumacker P, Truong LD, Overbeek P, Danesh FR. Drp1S600 phosphorylation regulates mitochondrial fission and progression of nephropathy in diabetic mice. Journal of Clinical Investigation. 2019 Jul;129(7):2807-2823.

January CT, Wann LS, Calkins H, et al (including Yancy CW). 2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society in Collaboration With the Society of Thoracic Surgeons. Circulation. 2019 Jul;140(2):E125-E151.

Liu Y, Wang XJ, Xu YM, Xue ZG, Zhang Y, Ning X, Chen X, Xue YG, Lu D, Zhang QH, Zhang F, Liu JX, Guo XG, Hwang KC, Huang YG, Rogers JA, Zhang YH. Harnessing the interface mechanics of hard films and soft substrates for 3D assembly by controlled buckling. Proceedings of the National Academy of Sciences of the United States of America. 2019 Jul;116(31):15368-15377.

Ng LCT, Vien TN, Yarov-Yarovoy V, DeCaen PG. Opening TRPP2 (PKD2L1) requires the transfer of gating charges. Proceedings of the National Academy of Sciences of the United States of America. 2019 Jul;116(31):15540-15549.

Owens DK, Davidson KW, Krist AH, Barry MJ, Cabana M, Caughey AB, Doubeni CA, Epling JW, Jr., Kemper AR, Kubik M, Landefeld CS, Mangione CM, Pbert L, Silverstein M, Simon MA, Tseng CW, Wong JB. Screening for Hepatitis B Virus Infection in Pregnant Women: US Preventive Services Task Force Reaffirmation Recommendation Statement. JAMA-Journal of the American Medical Association. 2019 Jul 23;322(4):349-354.

Ponds FA, Fockens P, Lei A, Neuhaus H, Beyna T, Kandler J, Frieling T, Chiu PY, Wu JCY, Wong VWY, Costamagna G, Familiari P, Kahrilas PJ, Pandolfino JE, Smout A, Bredenoord AJ. Effect of Peroral Endoscopic Myotomy vs Pneumatic Dilation on Symptom Severity and Treatment Outcomes Among Treatment-Naive Patients With Achalasia A Randomized Clinical Trial. JAMA-Journal of the American Medical Association. 2019 Jul;322(2):134-144.

Roberts MY, Curtis PR, Sone BJ, Hampton LH. Association of Parent Training With Child Language Development: A Systematic Review and Meta-analysis. JAMA Pediatrics. 2019 Jul 1;173(7):671-680.

Salpietro V, Dixon CL, Guo H, et al. (including Menacacci NE) AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders. Nature Communications. 2019 Jul;10:16.

Schnitzer TJ, Easton R, Pang S, Levinson DJ, Pixton G, Viktrup L, Davignon I, Brown MT, West CR, Verburg KM. Effect of Tanezumab on Joint Pain, Physical Function, and Patient Global Assessment of Osteoarthritis Among Patients With Osteoarthritis of the Hip or Knee A Randomized Clinical Trial. JAMA-Journal of the American Medical Association. 2019 Jul;322(1):37-48.

Sin-Chan P, Mumal I, Suwal T, et al. (including Schnitzer TJ). A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor. Cancer Cell. 2019 Jul;36(1):51.

Singer BD, Chandel NS. Immunometabolism of pro-repair cells. Journal of Clinical Investigation. 2019 Jul;129(7):2597-2607.

Song EM, Chiang CH, Li R, Jin X, Zhao JN, Hill M, Xia Y, Li LZ, Huang YM, Won SM, Yu KJ, Sheng X, Fang H, Alam MA, Huang YG, Viventi J, Chang JK, Rogers JA. Flexible electronic/optoelectronic microsystems with scalable designs for chronic biointegration. Proceedings of the National Academy of Sciences of the United States of America. 2019 Jul;116(31):15398-15406.

Torres C, Mancinelli G, Cordoba-Chacon J, Viswakarma N, Castellanos K, Grimaldo S, Kumar S, Principe D, Dorman MJ, McKinney R, Hirsch E, Dawson D, Munshi HG, Rana A, Grippo PJ. p110 gamma deficiency protects against pancreatic carcinogenesis yet predisposes to diet-induced hepatotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 2019 Jul;116(29):14724-14733.

Zeitler B, Froelich S, Marlen K, Shivak DA, Yu Q, Li D, Pearl JR, Miller JC, Zhang L, Paschon DE, Hinkley SJ, Ankoudinova I, Lam S, Guschin D, Kopan L, Cherone JM, Nguyen HOB, Qiao GJ, Ataei Y, Mendel MC, Amora R, Surosky R, Laganiere J, Vu BJ, Narayanan A, Sedaghat Y, Tillack K, Thiede C, Gartner A, Kwak S, Bard J, Mrzljak L, Park L, Heikkinen T, Lehtimaki KK, Svedberg MM, Haggkvist J, Tari L, Toth M, Varrone A, Halldin C, Kudwa AE, Ramboz S, Day M, Kondapalli J, Surmeier DJ, Urnov FD, Gregory PD, Rebar EJ, Munoz-Sanjuan I, Zhang HS. Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease. Nature Medicine. 2019 Jul;25(7):1131.

Zhao H, Li K, Han M, Zhu F, Vazquez-Guardado A, Guo P, Xie Z, Park Y, Chen L, Wang X, Luan H, Yang Y, Wang H, Liang C, Xue Y, Schaller RD, Chanda D, Huang Y, Zhang Y, Rogers JA. Buckling and twisting of advanced materials into morphable 3D mesostructures. Proceedings of the National Academy of Sciences of the United States of America. 2019 Jul 2;116(27):13239-13248.

Zhou XP, Chen Y, Mok KY, et al. (including Mesulam MM, Kerwin D, Lipowski K, Wu CK, Johnson N, Grafman J). Non-coding variability at the APOE locus contributes to the Alzheimer's risk. Nature Communications. 2019 Jul;10:16.

Anderson CAM, Thorndike AN, Lichtenstein AH, Van Horn L, Kris-Etherton PM, Foraker R, Spees C. Innovation to Create a Healthy and Sustainable Food System: A Science Advisory From the American Heart Association. Circulation. 2019 Jun;139(23):E1025-E1032.

Ardila D, Kiraly AP, Bharadwaj S, Choi B, Reicher JJ, Peng L, Tse D, Etemadi M, Ye WX, Corrado G, Naidich DP, Shetty S. End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography. Nature Medicine. 2019 Jun;25(6):954.

Bao XJ, Gjorgieva E, Shanahan LK, Howard JD, Kahnt T, Gottfried JA. Grid-like Neural Representations Support Olfactory Navigation of a Two-Dimensional Odor Space. Neuron. 2019 Jun;102(5):1066.

Bhatt SP, Balte PP, Schwartz JE, Cassano PA, Couper D, Jacobs DR, Jr., Kalhan R, O'Connor GT, Yende S, Sanders JL, Umans JG, Dransfield MT, Chaves PH, White WB, Oelsner EC. Discriminative Accuracy of FEV1:FVC Thresholds for COPD-Related Hospitalization and Mortality. JAMA-Journal of the American Medical Association. 2019 Jun 25;321(24):2438-2447.

Brickner DG, Randise-Hinchliff C, Corbin ML, Liang JM, Kim S, Sump B, Durso A, Kim SH, Satomura A, Schmit H, Coukos R, Hwang S, Watson R, Brickner JH. The Role of Transcription Factors and Nuclear Pore Proteins in Controlling the Spatial Organization of the Yeast Genome. Developmental Cell. 2019 Jun;49(6):936.

Croft AP, Campos J, Jansen K, Turner JD, Marshall J, Attar M, Savary L, Wehmeyer C, Naylor AJ, Kemble S, Begum J, Durholz K, Perlman H, Barone F, McGettrick HM, Fearon DT, Wei K, Raychaudhuri S, Korsunsky I, Brenner MB, Coles M, Sansom SN, Filer A, Buckley CD. Distinct fibroblast subsets drive inflammation and damage in arthritis. Nature. 2019 Jun;570(7760):246.

Davis LE, Bolejack V, Ryan CW, Ganjoo KN, Loggers ET, Chawla S, Agulnik M, Livingston MB, Reed D, Keedy V, Rushing D, Okuno S, Reinke DK, Riedel RF, Attia S, Mascarenhas L, Maki RG. Randomized Double-Blind Phase II Study of Regorafenib in Patients With Metastatic Osteosarcoma. Journal of Clinical Oncology. 2019 Jun;37(16):1424.

Flegontov P, Altinisik NE, Changmai P, Rohland N, Mallick S, Adamski N, Bolnick DA, Broomandkhoshbacht N, Candilio F, Culleton BJ, Flegontova O, Friesen TM, Jeong C, Harper TK, Keating D, Kennett DJ, Kim AM, Lamnidis TC, Lawson AM, Olalde I, Oppenheimer J, Potter B, Raff J, Sattler RA, Skoglund P, Stewardson K, Vajda EJ, Vasilyev S, Veselovskaya E, Hayes MG, O'Rourke DH, Krause J, Pinhasi R, Reich D, Schiffels S. Palaeo-Eskimo genetic ancestry and the peopling of Chukotka and North America. Nature. 2019 Jun;570(7760):236.

Girard M, Wang SZ, Du JS, Das A, Huang ZY, Dravid VP, Lee B, Mirkin CA, de la Cruz MO. Particle analogs of electrons in colloidal crystals. Science. 2019 Jun;364(6446):1174.

Grundy SM, Stone NJ, Bailey AL, Beam C, Birtcher KK, Blumenthal RS, Braun LT, de Ferranti S, Faiella-Tommasino J, Forman DE, Goldberg R, Heidenreich PA, Hlatky MA, Jones DW, Lloyd-Jones D, Lopez-Pajares N, Ndumele CE, Orringer CE, Peralta CA, Saseen JJ, Smith SC, Sperling L, Virani SS, Yeboah J. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2019 Jun;139(25):E1046-E1081.

Grundy SM, Stone NJ, Bailey AL, Beam C, Birtcher KK, Blumenthal RS, Braun LT, de Ferranti S, Faiella-Tommasino J, Forman DE, Goldberg R, Heidenreich PA, Hlatky MA, Jones DW, Lloyd-Jones D, Lopez-Pajares N, Ndumele CE, Orringer CE, Peralta CA, Saseen JJ, Smith SC, Sperling L, Virani SS, Yeboah J. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2019 Jun;139(25):E1082-E1143.

Grundy SM, Stone NJ, Bailey AL, Beam C, Birtcher KK, Blumenthal RS, Braun LT, de Ferranti S, Faiella-Tommasino J, Forman DE, Goldberg R, Heidenreich PA, Hlatky MA, Jones DW, Lloyd-Jones D, Lopez-Pajares N, Ndumele CE, Orringer CE, Peralta CA, Saseen JJ, Smith SC, Sperling L, Virani SS, Yeboah J, Guideline Writing Comm C. 2018 Cholesterol Clinical Practice Guidelines: Synopsis of the 2018 American Heart Association/American College of Cardiology/Multisociety Cholesterol Guideline. Annals of Internal Medicine. 2019 Jun;170(11):779.

Ison MG, Lebeis TA, Barros N, Lewis GD, Massoth LR. Case 20-2019: A 52-Year-Old Woman with Fever and Rash after Heart Transplantation. New England Journal of Medicine. 2019 Jun 27;380(26):2564-2573.

Jiang ZF, Li W, Hu XC, Zhang QY, Sun T, Cui SD, Wang SS, Ouyang QC, Yin YM, Geng CZ, Tong ZS, Cheng Y, Pan YY, Sun YP, Wang H, Ouyang T, Gu KS, Feng JF, Wang XJ, Wang SB, Liu TS, Gao JH, Cristofanilli MSM, Ning ZQ, Lu XP. Tucidinostat plus exemestane for postmenopausal patients with advanced, hormone receptor-positive breast cancer (ACE): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Oncology. 2019 Jun;20(6):806-815.

Liu J, Carnero-Montoro E, van Dongen J, Lent S, Nedeljkovic I, Ligthart S, Tsai PC, Martin TC, Mandaviya PR, Jansen R, Peters MJ, Duijts L, Jaddoe VWV, Tiemeier H, Felix JF, Willemsen G, de Geus EJC, Chu AY, Levy D, Hwang SJ, Bressler J, Gondalia R, Salfati EL, Herder C, Hidalgo BA, Tanaka T, Moore AZ, Lemaitre RN, Jhun MA, Smith JA, Sotoodehnia N, Bandinelli S, Ferrucci L, Arnett DK, Grallert H, Assimes TL, Hou L, Baccarelli A, Whitsel EA, van Dijk KW, Amin N, Uitterlinden AG, Sijbrands EJG, Franco OH, Dehghan A, Spector TD, Dupuis J, Hivert MF, Rotter JI, Meigs JB, Pankow JS, van Meurs JBJ, Isaacs A, Boomsma DI, Bell JT, Demirkan A, van Duijn CM. An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis. Nature Communications. 2019 Jun;10:11.

Lloyd-Jones DM, Braun LT, Ndumele CE, Smith SC, Sperling LS, Virani SS, Blumenthal RS. Use of Risk Assessment Tools to Guide Decision-Making in the Primary Prevention of Atherosclerotic Cardiovascular Disease: A Special Report From the American Heart Association and American College of Cardiology. Circulation. 2019 Jun;139(25):E1162-E1177.

Lu J, Periz G, Lu YN, Tang Q, Liu Y, Zhang T, Shah Y, Thombre R, Aljumaah R, Li W, Mojsilovic-Petrovic J, Ji Y, Johnson K, Kalb R, Wang J. L3MBTL1 regulates ALS/FTD-associated proteotoxicity and quality control. Nature Neuroscience. 2019 Jun;22(6):875-886.

Matei D, Filiaci V, Randall ME, Mutch D, Steinhoff MM, DiSilvestro PA, Moxley KM, Kim YM, Powell MA, O'Malley DM, Spirtos NM, Small W, Tewari KS, Richards WE, Nakayama J, Matulonis UA, Huang HQ, Miller DS. Adjuvant Chemotherapy plus Radiation for Locally Advanced Endometrial Cancer. New England Journal of Medicine. 2019 Jun;380(24):2317-2326.

Owens DK, Davidson K, Krist AH, Barry MJ, Cabana M, Caughey AB, Curry SJ, Doubeni CA, Epling JW, Kubik M, Landefeld CS, Mangione CM, Pbert L, Silverstein M, Simon MA, Tseng CW, Wong JB, Force USPST. Screening for HIV Infection US Preventive Services Task Force Recommendation Statement. JAMA-Journal of the American Medical Association. 2019 Jun;321(23):2326-2336.

Owens DK, Davidson K, Krist AH, Barry MJ, Cabana M, Caughey AB, Curry SJ, Doubeni CA, Epling JW, Kubik M, Landefeld CS, Mangione CM, Pbert L, Silverstein M, Simon MA, Tseng CW, Wong JB, Force USPST. Preexposure Prophylaxis for the Prevention of HIV Infection US Preventive Services Task Force Recommendation Statement. JAMA-Journal of the American Medical Association. 2019 Jun;321(22):2203-2213.

Ro SY, Schachner LF, Koo CW, Purohit R, Remis JP, Kenney GE, Liauw BW, Thomas PM, Patrie SM, Kelleher NL, Rosenzweig AC. Native top-down mass spectrometry provides insights into the copper centers of membrane-bound methane monooxygenase. Nature Communications. 2019 Jun;10:12.

Shah SJ, Voors AA, McMurray JJV, Kitzman DW, Viethen T, Wirtz AB, Huang E, Pap AF, Solomon SD. Effect of Neladenoson Bialanate on Exercise Capacity Among Patients With Heart Failure With Preserved Ejection Fraction A Randomized Clinical Trial. JAMA-Journal of the American Medical Association. 2019 Jun;321(21):2101-2112.

Sharman JP, Coutre SE, Furman RR, Cheson BD, Pagel JM, Hillmen P, Barrientos JC, Zelenetz AD, Kipps TJ, Flinn IW, Ghia P, Eradat H, Ervin T, Lamanna N, Coiffier B, Pettitt AR, Ma S, Tausch E, Cramer P, Huang J, Mitra S, Hallek M, O'Brien SM, Stilgenbauer S. Final Results of a Randomized, Phase III Study of Rituximab With or Without Idelalisib Followed by Open-Label Idelalisib in Patients With Relapsed Chronic Lymphocytic Leukemia. Journal of Clinical Oncology. 2019 Jun;37(16):1391.

Sparano JA, Gray RJ, Ravdin PM, Makower DF, Pritchard KI, Albain KS, Hayes DF, Geyer CE, Dees EC, Goetz MP, Olson JA, Lively T, Badve SS, Saphner TJ, Wagner LI, Whelan TJ, Ellis MJ, Paik S, Wood WC, Keane MM, Moreno HLG, Reddy PS, Goggins TF, Mayer IA, Brufsky AM, Toppmeyer DL, Kaklamani VG, Berenberg JL, Abrams J, Sledge GW. Clinical and Genomic Risk to Guide the Use of Adjuvant Therapy for Breast Cancer. New England Journal of Medicine. 2019 Jun;380(25):2395-2405.

Tiwari P, Blank A, Cui C, Schoenfelt KQ, Zhou G, Xu Y, Khramtsova G, Olopade F, Shah AM, Khan SA, Rosner MR, Becker L. Metabolically activated adipose tissue macrophages link obesity to triple-negative breast cancer. Journal of Experimental Medicine. 2019 Jun 3;216(6):1345-1358.

Yao Q, Khan MP, Merceron C, LaGory EL, Tata Z, Mangiavini L, Hu J, Vemulapalli K, Chandel NS, Giaccia AJ, Schipani E. Suppressing Mitochondrial Respiration Is Critical for Hypoxia Tolerance in the Fetal Growth Plate. Developmental Cell. 2019 Jun 3;49(5):748-763.e747.

Zhang F, Wei K, Slowikowski K, Fonseka CY, Rao DA, Kelly S, Goodman SM, Tabechian D, Hughes LB, Salomon-Escoto K, Watts GFM, Jonsson AH, Rangel-Moreno J, Meednu N, Rozo C, Apruzzese W, Eisenhaure TM, Lieb DJ, Boyle DL, Mandelin AM, Boyce BF, DiCarlo E, Gravallese EM, Gregersen PK, Moreland L, Firestein GS, Hacohen N, Nusbaum C, Lederer JA, Perlman H, Pitzalis C, Filer A, Holers VM, Bykerk VP, Donlin LT, Anolik JH, Brenner MB, Raychaudhuri S, Albrecht J, Bridges SL, Buckley CD, Buckner JH, Dolan J, Guthridge JM, Gutierrez-Arcelus M, Ivashkiv LB, James EA, James JA, Keegan J, Lee YC, McGeachy MJ, McNamara MA, Mears JR, Mizoguchi F, Nguyen JP, Noma A, Orange DE, Rohani-Pichavant M, Ritchlin C, Robinson WH, Seshadri A, Sutherby D, Seifert J, Turner JD, Utz PJ, Accelerating Medicines P. Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry. Nature Immunology. 2019 Jul;20(7):928.

Zhu YM, Zou XH, Dean AE, O' Brien J, Gao YC, Tran EL, Park SH, Liu GX, Kieffer MB, Jiang HY, Stauffer ME, Hart R, Quan SH, Satchell KJF, Horikoshi N, Bonini M, Gius D. Lysine 68 acetylation directs MnSOD as a tetrameric detoxification complex versus a monomeric tumor promoter. Nature Communications. 2019 Jun;10:15.

Adelman JS, Applebaum JR, Schechter CB, Berger MA, Reissman SH, Thota R, Racine AD, Vawdrey DK, Green RA, Salmasian H, Schiff GD, Wright A, Landman A, Bates DW, Koppel R, Galanter WL, Lambert BL, Paparella S, Southern WN. Effect of Restriction of the Number of Concurrently Open Records in an Electronic Health Record on Wrong-Patient Order Errors A Randomized Clinical Trial. JAMA-Journal of the American Medical Association. 2019;321(18):1780-1787.

Baker CW, Glassman AR, Beaulieu WT, et al. (including Jampol LM). Effect of Initial Management With Aflibercept vs Laser Photocoagulation vs Observation on Vision Loss Among Patients With Diabetic Macular Edema Involving the Center of the Macula and Good Visual Acuity A Randomized Clinical Trial. JAMA-Journal of the American Medical Association. 2019;321(19):1880-1894.

Beura LK, Fares-Frederickson NJ, Steinert EM, Scott MC, Thompson EA, Fraser KA, Schenke JM, Vezys V, Masopust D. CD4(+) resident memory T cells dominate immunosurveillance and orchestrate local recall responses. Journal of Experimental Medicine. 2019;216(5):1214-1229.

Cedernaes J, Huang WY, Ramsey KM, Waldeck N, Cheng L, Marcheva B, Omura C, Kobayashi Y, Peek CB, Levine DC, Dhir R, Awatramani R, Bradfield CA, Wang XZA, Takahashi JS, Mokadem M, Ahima RS, Bass J. Transcriptional Basis for Rhythmic Control of Hunger and Metabolism within the AgRP Neuron. Cell Metabolism. 2019;29(5):1078.

Chang SM, Messersmith H, Ahluwalia M, Andrews D, Brastianos PK, Gaspar LE, Gatson NTN, Jordan JT, Khasraw M, Lassman AB, Maues J, Mrugala M, Raizer J, Schiff D, Stevens G, Sumrall A, van den Bent M, Vogelbaum MA. Anticonvulsant Prophylaxis and Steroid Use in Adults With Metastatic Brain Tumors: ASCO and SNO Endorsement of the Congress of Neurological Surgeons Guidelines. Journal of Clinical Oncology. 2019;37(13):1130.

Diener HC, Sacco RL, Easton JD, Granger CB, Bernstein RA, Uchiyama S, Kreuzer J, Cronin L, Cotton D, Grauer C, Brueckmann M, Chernyatina M, Donnan G, Ferro JM, Grond M, Kallmunzer B, Krupinski J, Lee BC, Lemmens R, Masjuan J, Odinak M, Saver JL, Schellinger PD, Toni D, Toyoda K. Dabigatran for Prevention of Stroke after Embolic Stroke of Undetermined Source. New England Journal of Medicine. 2019;380(20):1906-1917.

Feigin VL, Nichols E, Alam T, et al. (including Yano Y). Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurology. 2019;18(5):459-480.

Gyamfi-Bannerman C, Zupancic JAF, Sandoval G, Grobman WA, et al. Cost-effectiveness of Antenatal Corticosteroid Therapy vs No Therapy in Women at Risk of Late Preterm Delivery A Secondary Analysis of a Randomized Clinical Trial. JAMA Pediatrics. 2019;173(5):462-468.

Ji Z, He LZ, Regev A, Struhl K. Inflammatory regulatory network mediated by the joint action of NF-kB, STAT3, and AP-1 factors is involved in many human cancers. Proceedings of the National Academy of Sciences of the United States of America. 2019;116(19):9453-9462.

Lazarus SC, Krishnan JA, King TS, et al. (including Smith L) Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level. New England Journal of Medicine. 2019;380(21):2009-2019.

Mack MJ, Leon MB, Thourani VH, Makkar R, Kodali SK, Russo M, Kapadia SR, Malaisrie SC, Cohen DJ, Pibarot P, Leipsic J, Hahn RT, Blanke P, Williams MR, McCabe JM, Brown DL, Babaliaros V, Goldman S, Szeto WY, Genereux P, Pershad A, Pocock SJ, Alu MC, Webb JG, Smith CR, Investigators P. Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients. New England Journal of Medicine. 2019;380(18):1695-1705.

Martinez-Velez N, Garcia-Moure M, Marigil M, Gonzalez-Huarriz M, Puigdelloses M, Perez-Larraya JG, Zalacain M, Marrodan L, Varela-Guruceaga M, Laspidea V, Aristu JJ, Ramos LI, Tejada-Solis S, Diez-Valle R, Jones C, Mackay A, Martinez-Climent JA, Garcia-Barchino MJ, Raabe E, Monje M, Becher OJ, Junier MP, El-Habr EA, Chneiweiss H, Aldave G, Jiang H, Fueyo J, Patino-Garcia A, Gomez-Manzano C, Alonso MM. The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models. Nature Communications. 2019;10:10.

Moore KN, Secord AA, Geller MA, Miller DS, Cloven N, Fleming GF, Hendrickson AEW, Azodi M, DiSilvestro P, Oza AM, Cristea M, Berek JS, Chan JK, Rimel BJ, Matei DE, Li Y, Sun KM, Luptakova K, Matulonis UA, Monk BJ. Niraparib monotherapy for late-line treatment of ovarian cancer (QUADRA): a multicentre, open-label, single-arm, phase 2 trial. Lancet Oncology. 2019;20(5):636-648.

Perak AM, Ning HY, Kit BK, de Ferranti SD, Van Horn LV, Wilkins JT, Lloyd-Jones DM. Trends in Levels of Lipids and Apolipoprotein B in US Youths Aged 6 to 19 Years, 1999-2016. JAMA-Journal of the American Medical Association. 2019;321(19):1895-1905.

Reynolds AW, Mata-Miguez J, Miro-Herrans A, Briggs-Cloud M, Sylestine A, Barajas-Olmos F, Garcia-Ortiz H, Rzhetskaya M, Orozco L, Raff JA, Hayes MG, Bolnick DA. Comparing signals of natural selection between three Indigenous North American populations. Proceedings of the National Academy of Sciences of the United States of America. 2019;116(19):9312-9317.

Wang SY, Qin L, Yamankurt G, Skakuj K, Huang ZY, Chen PC, Dominguez D, Lee A, Zhang B, Mirkin CA. Rational vaccinology with spherical nucleic acids. Proceedings of the National Academy of Sciences of the United States of America. 2019;116(21):10473-10481.

Warrington NM, Beaumont RN, Horikoshi M, et al. (including Nodzenski M, Scholtens DM, Lowe WL, Hayes MG). Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. Nature Genetics. 2019;51(5):804.

Watanabe S, Alexander M, Misharin AV, Budinger GRS. The role of macrophages in the resolution of inflammation. Journal Clinical Investigation. 2019;130.

Zhao JW, Lee EE, Kim J, Yang R, Chamseddin B, Ni CY, Gusho E, Xie Y, Chiang CM, Buszczak M, Zhan XW, Laimins L, Wang RC. Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus. Nature Communications. 2019;10:12.

Amsterdam SH, Stanev TK, Zhou Q, Lou AJ, Bergeron H, Darancet P, Hersam MC, Stern NP, Marks TJ. Electronic Coupling in Metallophthalocyanine-Transition Metal Dichalcogenide Mixed-Dimensional Heterojunctions. ACS Nano. 2019 Apr 23;13(4):4183-4190.

Bentley AR, Sung YJ, Brown MR, et al. (including Liu K). Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Nature Genetics. 2019 Apr;51(4):636.

Carota IA, Kenig-Kozloysky Y, Onay T, Scott R, Thomson BR, Souma T, Bartlett CS, Li YY, Procissi D, Ramirez V, Yamaguchi S, Tarjus A, Tanna CE, Li CJ, Eremina V, Vestweber D, Nadipupo SS, Breyer MD, Quaggin SE. Targeting VE-PTP phosphatase protects the kidney from diabetic injury. Journal of Experimental Medicine. 2019 Apr;216(4):936-949.

Curry SJ, Krist AH, Owens DK, Barry MJ, Cabana M, Caughey AB, Doubeni CA, Epling JW, Kemper AR, Kubik M, Landefeld CS, Mangione CM, Pbert L, Silverstein M, Simon MA, Tseng CW, Wong JB, Force USPST. Screening for Elevated Blood Lead Levels in Children and Pregnant Women US Preventive Services Task Force Recommendation Statement. JAMA-Journal of the American Medical Association. 2019 Apr;321(15):1502-1509.

Franzmeier N, Rubinski A, Neitzel J, et al. (including Mesulam MM, Mesulam MM, Rogalski E, Lipowski K, Weintraub S). The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory. Nature Communications. 2019 Apr;10:12.

Garrett-Bakelman FE, Darshi M, Green SJ, et al. (including Turek FW). The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight. Science. 2019 Apr;364(6436):144.

Gladstein S, Almassalha LM, Cherkezyan L, Chandler JE, Eshein A, Eid A, Zhang D, Wu WL, Bauer GM, Stephens AD, Morochnik S, Subramanian H, Marko JF, Ameer GA, Szleifer I, Backman V. Multimodal interference-based imaging of nanoscale structure and macromolecular motion uncovers UV induced cellular paroxysm. Nature Communications. 2019 Apr;10:15.

Kiraly B, Liu X, Wang L, Zhang Z, Mannix AJ, Fisher BL, Yakobson BI, Hersam MC, Guisinger NP. Borophene Synthesis on Au(111). ACS Nano. 2019 Apr 23;13(4):3816-3822.

Kuppermann N, Dayan PS, Levine DA, Vitale M, Tzimenatos L, Tunik MG, Saunders M, Ruddy RM, Roosevelt G, Rogers AJ, Powell EC, Nigrovic LE, Muenzer J, Linakis JG, Grisanti K, Jaffe DM, Hoyle JD, Greenberg R, Gattu R, Cruz AT, Crain EF, Cohen DM, Brayer A, Borgialli D, Bonsu B, Browne L, Blumberg S, Bennett JE, Atabaki SM, Anders J, Alpern ER, Miller B, Casper TC, Dean JM, Ramilo O, Mahajan P, Pecarn. A Clinical Prediction Rule to Identify Febrile Infants 60 Days and Younger at Low Risk for Serious Bacterial Infections. JAMA Pediatrics. 2019 Apr;173(4):342-351.

Liu XL, Wang LQ, Li SW, Rahn MS, Yakobson BI, Hersam MC. Geometric imaging of borophene polymorphs with functionalized probes. Nature Communications. 2019 Apr;10:7.

Ng K, Nimeiri HS, McCleary NJ, Abrams TA, Yurgelun MB, Cleary JM, Rubinson DA, Schrag D, Miksad R, Bullock AJ, Allen J, Zuckerman D, Chan E, Chan JA, Wolpin BM, Constantine M, Weckstein DJ, Faggen MA, Thomas CA, Kournioti C, Yuan C, Ganser C, Wilkinson B, Mackintosh C, Zheng H, Hollis BW, Meyerhardt JA, Fuchs CS. Effect of High-Dose vs Standard-Dose Vitamin D-3 Supplementation on Progression-Free Survival Among Patients With Advanced or Metastatic Colorectal Cancer The SUNSHINE Randomized Clinical Trial. JAMA-Journal of the American Medical Association. 2019 Apr;321(14):1370-1379.

Rodriguez AE, Ducker GS, Billingham LK, Martinez CA, Mainolfi N, Suri V, Friedman A, Manfredi MG, Weinberg SE, Rabinowitz JD, Chandel NS. Serine Metabolism Supports Macrophage IL-1 beta Production. Cell Metabolism. 2019 Apr;29(4):1003.

Tombal B, Saad F, Penson D, Hussain M, Sternberg CN, Morlock R, Ramaswatny K, Ivanescu C, Attard G. Patient-reported outcomes following enzalutamide or placebo in men with non-metastatic, castration-resistant prostate cancer (PROSPER): a multicentre, randomised, double-blind, phase 3 trial. Lancet Oncology. 2019 Apr;20(4):556-569.

Waikar SS, Srivastava A, Palsson R, Shafi T, Hsu CY, Sharma K, Lash JP, Chen J, He J, Lieske J, Xie DW, Zhang XM, Feldman HI, Curhan GC, Appel LJ, Go AS, Kusek JW, Rao P, Rahman M, Townsend RR, Chronic Renal Insufficiency C. Association of Urinary Oxalate Excretion With the Risk of Chronic Kidney Disease Progression. JAMA Internal Medicine. 2019 Apr;179(4):542-551.

Yamawaki N, Li XJ, Lambot L, Ren LY, Radulovic J, Shepherd GMG. Long-range inhibitory intersection of a retrosplenial thalamocortical circuit by apical tuft-targeting CA1 neurons. Nature Neuroscience. 2019 Apr;22(4):618.

Zhao W, Wang X, Deik AA, Hanna DB, Wang T, Haberlen SA, Shah SJ, Lazar JM, Hodis HN, Landay AL, Yu B, Gustafson D, Anastos K, Post WS, Clish CB, Kaplan RC, Qi Q. Elevated Plasma Ceramides Are Associated With Antiretroviral Therapy Use and Progression of Carotid Artery Atherosclerosis in HIV Infection. Circulation. 2019 Apr 23;139(17):2003-2011.

Banerjee S, Gusho E, Gaughan C, Dong BH, Gu XR, Holvey-Bates E, Talukdar M, Li YZ, Weiss SR, Sicheri F, Saunthararajah Y, Stark GR, Silverman RH. OAS-RNase L innate immune pathway mediates the cytotoxicity of a DNA-demethylating drug. Proceedings of the National Academy of Sciences of the United States of America. 2019 Mar;116(11):5071-5076.

Chang BJ, Kittisopikul M, Dean KM, Roudot P, Welf ES, Fiolka R. Universal light-sheet generation with field synthesis. Nature Methods. 2019 Mar;16(3):235-238.

Chen PC, Liu MH, Du JSS, Meckes B, Wang SZ, Lin HX, Dravid VP, Wolverton C, Mirkin CA. Interface and heterostructure design in polyelemental nanoparticles. Science. 2019 Mar;363(6430):959.

Chung HU, Kim BH, Lee JY, Lee J, Xie ZQ, Ibler EM, Lee K, Banks A, Jeong JY, Kim J, Ogle C, Grande D, Yu Y, Jang H, Assem P, Ryu D, Kwak JW, Namkoong M, Park JB, Lee Y, Kim DH, Ryu A, Jeong J, You K, Ji BW, Liu ZJ, Huo QZ, Feng X, Deng YJ, Xu YS, Jang KI, Kim J, Zhang YH, Ghaffari R, Rand CM, Schau M, Hamvas A, Weese-Mayer DE, Huang YG, Lee SM, Lee CH, Shanbhag NR, Paller AS, Xu S, Rogers JA. Binodal, wireless epidermal electronic systems with in-sensor analytics for neonatal intensive care. Science. 2019 Mar;363(6430):947.

Crowley JJ, Szatkiewicz J, Kahler AK, Giusti-Rodriguez P, Ancalade N, Booker JK, Carr JL, Crawford GE, Losh M, Stockmeier CA, Taylor AK, Piven J, Sullivan PF. Common-variant associations with fragile X syndrome. Molecular Psychiatry. 2019 Mar;24(3):338-344.

Hoeman CM, Cordero FJ, Hu G, Misuraca K, Romero MM, Cardona HJ, Nazarian J, Hashizume R, McLendon R, Yu P, Procissi D, Gadd S, Becher OJ. ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis. Nature Communications. 2019 Mar;10:15.

Hoxhaj G, Ben-Sahra I, Lockwood SE, Timson RC, Byles V, Henning GT, Gao P, Selfors LM, Asara JM, Manning BD. Direct stimulation of NADP(+) synthesis through Akt-mediated phosphorylation of NAD kinase. Science. 2019 Mar;363(6431):1088.

Hu YM, Li M, Lu QS, et.al. (including Weintraub S.) A statistical framework for cross-tissue transcriptome-wide association analysis. Nature Genetics. 2019 Mar;51(3):568.

Krenzlin H, Behera P, Lorenz V, Passaro C, Zdioruk M, Nowicki MO, Grauwet K, Zhang H, Skubal M, Ito H, Zane R, Gutknecht M, Griessl MB, Ricklefs F, Ding L, Peled S, Rooj A, James CD, Cobbs CS, Cook CH, Chiocca EA, Lawler SE. Cytomegalovirus promotes murine glioblastoma growth via pericyte recruitment and angiogenesis. Journal of Clinical Investigation. 2019 Mar 11;130:1671-1683.

Kunkle BW, Grenier-Boley B, Sims R, et al. (including Bigio EH, Mesulam M, Weintraub S). Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Abeta, tau, immunity and lipid processing. Nature Genetics. 2019 Mar;51(3):414-430.

LeBleu VS, Kalluri R. Exosomes Exercise Inhibition of Anti-Tumor Immunity during Chemotherapy. Immunity. 2019 Mar;50(3):547-549.

Levine CS, Markus HR, Austin MK, Chen E, Miller GE. Students of color show health advantages when they attend schools that emphasize the value of diversity. Proceedings of the National Academy of Sciences of the United States of America. 2019 Mar;116(13):6013-6018.

Levine DM, Landon BE, Linder JA. Quality and Experience of Outpatient Care in the United States for Adults With or Without Primary Care. JAMA Internal Medicine. 2019 Mar;179(3):363-372.

McSharry SS, Beitel GJ. The Caspase-3 homolog DrICE regulates endocytic trafficking during Drosophila tracheal morphogenesis. Nature Communications. 2019 Mar;10:10.

O'Donnell M, Mente A, Rangarajan S, McQueen MJ, O'Leary N, Yin L, Liu XY, Swaminathan S, Khatib R, Rosengren A, Ferguson J, Smyth A, Lopez-Jaramillo P, Diaz R, Avezum A, Lanas F, Ismail N, Yusoff K, Dans A, Iqbal R, Szuba A, Mohammadifard N, Oguz A, Yusufali AH, Alhabib KF, Kruger IM, Yusuf R, Chifamba J, Yeates K, Dagenais G, Wielgosz A, Lear SA, Teo K, Yusuf S, Investigators P. Joint association of urinary sodium and potassium excretion with cardiovascular events and mortality: prospective cohort study. BMJ-British Medical Journal. 2019 Mar;364:14.

Piccini JP, Xu H, Cox M, Matsouaka RA, Fonarow GC, Butler J, Curtis AB, Desai N, Fang M, McCabe PJ, Page Ii RL, Turakhia M, Russo AM, Knight BP, Sidhu M, Hurwitz JL, Ellenbogen KA, Lewis WR. Adherence to Guideline-Directed Stroke Prevention Therapy for Atrial Fibrillation Is Achievable. Circulation. 2019 Mar 19;139(12):1497-1506.

Zhao J, Chen AX, Gartrell RD, Silverman AM, Aparicio L, Chu T, Bordbar D, Shan D, Samanamud J, Mahajan A, Filip I, Orenbuch R, Goetz M, Yamaguchi JT, Cloney M, Horbinski C, Lukas RV, Raizer J, Rae AI, Yuan JZ, Canoll P, Bruce JN, Saenger YM, Sims P, Iwamoto FM, Sonabend AM, Rabadan R. Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma. Nature Medicine. 2019 Mar;25(3):462.

Zhong VW, Van Horn L, Cornelis MC, Wilkins JT, Ning HY, Carnethon MR, Greenland P, Mentz RJ, Tucker KL, Zhao LH, Norwood AF, Lloyd-Jones DM, Allen NB. Associations of Dietary Cholesterol or Egg Consumption With Incident Cardiovascular Disease and Mortality. JAMA-Journal of the American Medical Association. 2019 Mar;321(11):1081-1095.

Zhou GY, Lane G, Notoe T, Arabkheradmand G, Gottfried JA, Schuele SU, Rosenow JM, Olofsson JK, Wilson DA, Zelano C. Human olfactory-auditory integration requires phase synchrony between sensory cortices. Nature Communications. 2019 Mar;10:12.

Butin-Israeli V, Bui TM, Wiesolek HL, Mascarenhas L, Lee JJ, Mehl LC, Knutson KR, Adam SA, Goldman RD, Beyder A, Wiesmuller L, Hanauer SB, Sumagin R. Neutrophil-induced genomic instability impedes resolution of inflammation and wound healing. Journal of Clinical Investigation. 2019 Feb 1;129(2):712-726.

Cella D, Grunwald V, Escudier B, Hammers HJ, George S, Nathan P, Grimm MO, Rini BI, Doan J, Ivanescu C, Paty J, Mekan S, Motzer RJ. Patient-reported outcomes of patients with advanced renal cell carcinoma treated with nivolumab plus ipilimumab versus sunitinib (CheckMate 214): a randomised, phase 3 trial. Lancet Oncology. 2019 Feb;20(2):297-310.

Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Davidson K, Doubeni CA, Epling JW, Grossman DC, Kemper AR, Kubik M, Landefeld CS, Mangione CM, Silverstein M, Simon MA, Tseng CW, Wong JB, Force USPST. Interventions to Prevent Perinatal Depression US Preventive Services Task Force Recommendation Statement. JAMA. 2019 Feb;321(6):580-587.

Daya M, Rafaels N, Brunetti TM, et al. (including Grammer L). Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations. Nature Communications. 2019 Feb;10:13.

Elfassy T, Swift SL, Glymour MM, Calonico S, Jacobs DR, Mayeda ER, Kershaw KN, Kiefe C, Al Hazzouri AZ. Associations of Income Volatility With Incident Cardiovascular Disease and All-Cause Mortality in a US Cohort 1990 to 2015. Circulation. 2019 Feb;139(7):850-859.

Frey TM, Florin TA, Caruso M, Zhang NH, Zhang Y, Mittiga MR. Effect of Intranasal Ketamine vs Fentanyl on Pain Reduction for Extremity Injuries in Children The PRIME Randomized Clinical Trial. JAMA Pediatrics. 2019 Feb;173(2):140-146.

Gerson JN, Handorf E, Villa D, Gerrie AS, Chapani P, Li S, Medeiros LJ, Wang MI, Cohen JB, Calzada O, Churnetski MC, Hill BT, Sawalha Y, Hernandez-Ilizaliturri FJ, Kothari S, Vose JM, Bast MA, Fenske TS, Gari SNR, Maddocks KJ, Bond D, Bachanova V, Kolla B, Chavez J, Shah B, Lansigan F, Burns TF, Donovan AM, Wagner-Johnston N, Messmer M, Mehta A, Anderson JK, Reddy N, Kovach AE, Landsburg DJ, Glenn M, Inwards DJ, Karmali R, Kaplan JB, Caimi PF, Rajguru S, Evens A, Klein A, Umyarova E, Pulluri B, Amengual JE, Lue JK, Diefenbach C, Fisher RI, Barta SK. Survival Outcomes of Younger Patients With Mantle Cell Lymphoma Treated in the Rituximab Era. Journal of Clinical Oncology. 2019 Feb;37(6):471.

Laramy CR, Lopez-Rios H, O'Brien MN, Girard M, Stawicki RJ, Lee B, de la Cruz MO, Mirkin CA. Controlled Symmetry Breaking in Colloidal Crystal Engineering with DNA. ACS Nano. 2019 Feb;13(2):1412-1420.

Lazic D, Sagare AP, Nikolakopoulou AM, Griffin JH, Vassar R, Zlokovic BV. 3K3A-activated protein C blocks amyloidogenic BACE1 pathway and improves functional outcome in mice. Journal of Experimental Medicine. 2019 Feb 4;216(2):279-293.

Liu M, Jiang Y, Wedow R, (including Cornelis MC). Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use. Nature Genetics. 2019 Feb;51(2):237-244.

Li WJ, Gauthier JM, Higashikubo R, Hsiao HM, Tanaka S, Vuong L, Ritter JH, Tong AY, Wong BW, Hachem RR, Puri V, Bharat A, Krupnick AS, Hsieh CS, Baldwin WM, Kelly FL, Palmer SM, Gelman AE, Kreisel D. Bronchus-associated lymphoid tissue-resident Foxp3(+) T lymphocytes prevent antibody-mediated lung rejection. Journal of Clinical Investigation. 2019 Feb;129(2):556-568.

McCann ME, de Graaff JC, Dorris L, et al. (including Surantham S). Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy (GAS): an international, multicentre, randomised, controlled equivalence trial. Lancet. 2019 Feb;393(10172):664-677.

Nan KW, Wang HL, Ning X, Miller KA, Wei C, Liu YP, Li HB, Xue YG, Xie ZQ, Luan HW, Zhang YH, Huang YG, Rogers JA, Braun PV. Soft Three-Dimensional Microscale Vibratory Platforms for Characterization of Nano-Thin Polymer Films. ACS Nano. 2019 Jan;13(1):449-457.

Shuen AY, Lanni S, Panigrahi GB, Edwards M, Yu L, Campbell BB, Mandel A, Zhang C, Zhukova N, Alharbi M, Bernstein M, Bowers DC, Carroll S, Cole KA, Constantini S, Crooks B, Dvir R, Farah R, Hijiya N, George B, Laetsch TW, Larouche V, Lindhorst S, Luiten RC, Magimairajan V, Mason G, Mason W, Mordechai O, Mushtaq N, Nicholas G, Oren M, Palma L, Pedroza LA, Ramdas J, Samuel D, Schneider KW, Seeley A, Semotiuk K, Shamvil A, Sumerauer D, Toledano H, Tomboc P, Wierman M, Van Damme A, Lee YY, Zapotocky M, Bouffet E, Durno C, Aronson M, Gallinger S, Foulkes WD, Malkin D, Tabori U, Pearson CE. Functional Repair Assay for the Diagnosis of Constitutional Mismatch Repair Deficiency From Non-Neoplastic Tissue. Journal of Clinical Oncology. 2019 Feb;37(6):461.

Soberanes S, Misharin AV, Jairaman A, Morales-Nebreda L, McQuattie-Pimentel AC, Cho T, Hamanaka RB, Meliton AY, Reyfman PA, Walter JM, Chen CI, Chi M, Chiu S, Gonzalez-Gonzalez FJ, Antalek M, Abdala-Valencia H, Chiarella SE, Sun KA, Woods PS, Ghio AJ, Jain M, Perlman H, Ridge KM, Morimoto RI, Sznajder JI, Balch WE, Bhorade SM, Bharat A, Prakriya M, Chandel NS, Mutlu GM, Budinger GRS. Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis. Cell Metabolism. 2019 Feb;29(2):335.

Song B, Park SH, Zhao JC, Fong KW, Li SZ, Lee Y, Yang YA, Sridhar S, Lu XD, Abdulkadir SA, Vessella RL, Morrissey C, Kuzel TM, Catalona W, Yang XM, Yu JD. Targeting FOXA1-mediated repression of TGF-beta signaling suppresses castration-resistant prostate cancer progression. Journal of Clinical Investigation. 2019 Feb;129(2):569-582.

Tabaries S, McNulty A, Ouellet V, Annis MG, Dessureault M, Vinette M, Hachem Y, Lavoie B, Omeroglu A, Simon HG, Walsh LA, Kimbung S, Hedenfalk I, Siegel PM. Afadin cooperates with Claudin-2 to promote breast cancer metastasis. Genes & Development. 2019 Feb 1;33(3-4):180-193.

Tanimura A, Du YJ, Kondapalli J, Wokosin DL, Surmeier DJ. Cholinergic Interneurons Amplify Thalamostriatal Excitation of Striatal Indirect Pathway Neurons in Parkinson's Disease Models. Neuron. 2019 Feb;101(3):444.

Wang L, Shilatifard A. UTX Mutations in Human Cancer. Cancer Cell. 2019 Feb;35(2):168-176.

Zhang H, Brown RL, Wei Y, Zhao P, Liu S, Liu X, Deng Y, Hu X, Zhang J, Gao XD, Kang Y, Mercurio AM, Goel HL, Cheng C. CD44 splice isoform switching determines breast cancer stem cell state. Genes & Development. 2019 Feb 1;33(3-4):166-179.

Zhang S, Weinberg S, DeBerge M, Gainullina A, Schipma M, Kinchen JM, Ben-Sahra I, Gius DR, Yvan-Charvet L, Chandel NS, Schumacker PT, Thorp EB. Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair. Cell Metabolism. 2019 Feb;29(2):443.

Brown KA, Hedrick JL, Eichelsdoerfer DJ, Mirkin CA. Nanocombinatorics with Cantilever-Free Scanning Probe Arrays. ACS Nano. 2019 Jan;13(1):8-17.

Burt RK, Balabanov R, Burman J, Sharrack B, Snowden JA, Oliveira MC, Fagius J, Rose J, Nelson F, Barreira AA, Carlson K, Han XQ, Moraes D, Morgan A, Quigley K, Yaung K, Buckley R, Alldredge C, Clendenan A, Calvario MA, Henry J, Jovanovic B, Helenowski IB. Effect of Nonmyeloablative Hematopoietic Stem Cell Transplantation vs Continued Disease-Modifying Therapy on Disease Progression in Patients With Relapsing-Remitting Multiple Sclerosis A Randomized Clinical Trial. JAMA. 2019 Jan;321(2):165-174.

Carnethon MR, Neubauer LC, Greenland P. Competency-Based Postdoctoral Education. Circulation. 2019 Jan 15;139(3):310-312.

Chen SQ, Fan J, Zhang MH, Qin L, Dominguez D, Long A, Wang GX, Ma RQ, Li HB, Zhang Y, Fang DY, Sosman J, Zhang B. CD73 expression on effector T cells sustained by TGF-beta facilitates tumor resistance to anti-4-1BB/CD137 therapy. Nature Communications. 2019 Jan;10:15.

Chua KP, Fischer MA, Linder JA. Appropriateness of outpatient antibiotic prescribing among privately insured US patients: ICD-10-CM based cross sectional study. BMJ. 2019 Jan;364:8.

Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Davidson KW, Doubeni CA, Epling JW, Jr., Kemper AR, Kubik M, Landefeld CS, Mangione CM, Silverstein M, Simon MA, Tseng CW, Wong JB. Ocular Prophylaxis for Gonococcal Ophthalmia Neonatorum: US Preventive Services Task Force Reaffirmation Recommendation Statement. JAMA. 2019 Jan 29;321(4):394-398.

De T, Park CS, Perera MA. Cardiovascular Pharmacogenomics: Does It Matter If You're Black or White? In: Insel PA, ed. Annual Review of Pharmacology and Toxicology, Vol 59. Vol 59. Palo Alto: Annual Reviews; 2019:577-603.

Horwitz S, O'Connor OA, Pro B, et al. Brentuximab vedotin with chemotherapy for CD30-positive peripheral T-cell lymphoma (ECHELON-2): a global, double-blind, randomised, phase 3 trial. Lancet. 2019 Jan;393(10168):229-240.

Hurcombe JA, Hartley P, Lay AC, Ni L, Bedford JJ, Leader JP, Singh S, Murphy A, Scudamore CL, Marquez E, Barrington AF, Pinto V, Marchetti M, Wong LF, Uney J, Saleem MA, Mathieson PW, Patel S, Walker RJ, Woodgett JR, Quaggin SE, Welsh GI, Coward RJM. Podocyte GSK3 is an evolutionarily conserved critical regulator of kidney function. Nature Communications. 2019 Jan;10:17.

James SL, Theadom A, Ellenbogen RG, (including Yano Y). Global, regional, and national burden of traumatic brain injury and spinal cord injury, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurology. 2019 Jan;18(1):56-87.

Kluender EJ, Hedrick JL, Brown KA, Rao R, Meckes B, Du JS, Moreau LM, Maruyama B, Mirkin CA. Catalyst discovery through megalibraries of nanomaterials. Proceedings of the National Academy of Sciences of the United States of America. 2019 Jan 2;116(1):40-45.

McElroy GS, Chandel NS. Probing mitochondrial metabolism in vivo. Proceedings of the National Academy of Sciences of the United States of America. 2019 Jan 2;116(1):20-22.

Mickle AD, Won SM, Noh KN, Yoon J, Meacham KW, Xue YG, McIlvried LA, Copits BA, Samineni VK, Crawford KE, Kim DH, Srivastava P, Kim BH, Min S, Shiuan Y, Yun Y, Payne MA, Zhang JP, Jang H, Li YH, Lai HH, Huang YG, Park SI, Gereau RW, Rogers JA. A wireless closed-loop system for optogenetic peripheral neuromodulation. Nature. 2019 Jan;565(7739):361.

Nichols E, Szoeke CEI, Vollset SE, (including Yano Y). Global, regional, and national burden of Alzheimer's disease and other dementias, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurology. 2019 Jan;18(1):88-106.

Owonikoko TK, Dahlberg SE, Sica GL, Wagner LI, Wade JL, Srkalovic G, Lash BW, Leach JW, Leal TB, Aggarwal C, Ramalingam SS. Randomized Phase II Trial of Cisplatin and Etoposide in Combination With Veliparib or Placebo for Extensive-Stage Small-Cell Lung Cancer: ECOG-ACRIN 2511 Study. Journal of Clinical Oncology. 2019 Jan;37(3):222.

Patel RB, Shah SJ. Drug Targets for Heart Failure with Preserved Ejection Fraction: A Mechanistic Approach and Review of Contemporary Clinical Trials. In: Insel PA, ed. Annual Review of Pharmacology and Toxicology, Vol 59. Vol 59. Palo Alto: Annual Reviews; 2019:41-63.

Rice HC, de Malmazet D, Schreurs A, Frere S, Van Molle I, Volkov AN, Creemers E, Vertkin I, Nys J, Ranaivoson FM, Comoletti D, Savas JN, Remaut H, Balschun D, Wierda KD, Slutsky I, Farrow K, De Strooper B, de Wit J. Secreted amyloid-beta precursor protein functions as a GABA(B)R1a ligand to modulate synaptic transmission. Science. 2019 Jan;363(6423):143.

Saygin C, Matei D, Majeti R, Reizes O, Lathia JD. Targeting Cancer Stemness in the Clinic: From Hype to Hope. Cell Stem Cell. 2019 Jan 3;24(1):25-40.

Shenoy ES, Macy E, Rowe T, Blumenthal KG. Evaluation and Management of Penicillin Allergy A Review. JAMA. 2019 Jan;321(2):188-199.

Swarup V, Hinz FI, Rexach JE, et al (including Grafman J). Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia. Nature Medicine. 2019 Jan;25(1):152.

Treat-Jacobson D, McDermott MM, Bronas UG, Campia U, Collins TC, Criqui MH, Gardner AW, Hiatt WR, Regensteiner JG, Rich K, Amer Heart A. Optimal Exercise Programs for Patients With Peripheral Artery Disease: A Scientific Statement From the American Heart Association. Circulation. 2019 Jan;139(4):E10-E33.

Virani SS, Akeroyd JM, Nambi V, Michos ED, Morris PB, Nasir K, Smith SC, Jr., Stone NJ, Petersen LA, Ballantyne CM. Applicability and Cost Implications for Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors Based on the ODYSSEY Outcomes Trial. Circulation. 2019 Jan 15;139(3):410-412.

Zhao Z, Wang L, Volk AG, Birch NW, Stoltz KL, Bartom ET, Marshall SA, Rendleman EJ, Nestler CM, Shilati J, Schiltz GE, Crispino JD, Shilatifard A. Regulation of MLL/COMPASS stability through its proteolytic cleavage by taspase1 as a possible approach for clinical therapy of leukemia. Genes & Development. 2019 Jan 1;33(1-2):61-74.