High-Impact-Factor Research 2016

Bass J, Lazar MA. Circadian time signatures of fitness and disease. Science. 2016 Nov 25;354(6315):994-999.

Carson JL, Guyatt G, Heddle NM, Grossman BJ, Cohn CS, Fung MK, Gernsheimer T, Holcomb JB, Kaplan LJ, Katz LM, Peterson N, Ramsey G, Rao SV, Roback JD, Shander A, Tobian AAR. Clinical Practice Guidelines From the AABB Red Blood Cell Transfusion Thresholds and Storage. JAMA-Journal of the American Medical Association. 2016 Nov;316(19):2025-2035.

Eng AG, Kelver DA, Hedrick TP, Swanson GT. Transduction of group I mGluR-mediated synaptic plasticity by beta-arrestin2 signalling. Nature Communication. 2016 Nov 25;7:13571.

Feagan BG, Sandborn WJ, Gasink C, Jacobstein D, Lang Y, Friedman JR, Blank MA, Johanns J, Gao LL, Miao Y, Adedokun OJ, Sands BE, Hanauer SB, Vermeire S, Targan S, Ghosh S, de Villiers WJ, Colombel JF, Tulassay Z, Seidler U, Salzberg BA, Desreumaux P, Lee SD, Loftus EV, Dieleman LA, Katz S, Rutgeerts P, Grp U-I-US. Ustekinumab as Induction and Maintenance Therapy for Crohn's Disease. New England Journal of Medicine. 2016 Nov;375(20):1946-1960.

Galati DF, Mitchell BJ, Pearson CG. Subdistal Appendages Stabilize the Ups and Downs of Ciliary Life. Developmental Cell. 2016 Nov 21;39(4):387-389.

Kavousi M, Desai CS, Ayers C, Blumenthal RS, Budoff MJ, Mahabadi AA, Ikram MA, van der Lugt A, Hofman A, Erbel R, Khera A, Geisel MH, Jockel KH, Lehmann N, Hoffmann U, O'Donnell CJ, Massaro JM, Liu K, Mohlenkamp S, Ning H, Franco OH, Greenland P. Prevalence and Prognostic Implications of Coronary Artery Calcification in Low-Risk Women: A Meta-analysis. JAMA-Journal of the American Medical Association. 2016 Nov 22;316(20):2126-2134.

Koh A, Kang D, Xue Y, Lee S, Pielak RM, Kim J, Hwang T, Min S, Banks A, Bastien P, Manco MC, Wang L, Ammann KR, Jang KI, Won P, Han S, Ghaffari R, Paik U, Slepian MJ, Balooch G, Huang Y, Rogers JA. A soft, wearable microfluidic device for the capture, storage, and colorimetric sensing of sweat. Science Translational Medicine. 2016 Nov 23;8(366):366ra165.

Ledermann JA, Harter P, Gourley C, Friedlander M, Vergote I, Rustin G, Scott C, Meier W, Shapira-Frommer R, Safra T, Matei D, Fielding A, Spencer S, Rowe P, Lowe E, Hodgson D, Sovak MA, Matulonis U. Overall survival in patients with platinum-sensitive recurrent serous ovarian cancer receiving olaparib maintenance monotherapy: an updated analysis from a randomised, placebo-controlled, double-blind, phase 2 trial. Lancet Oncology. 2016 Nov;17(11):1579-1589.

Park JK, Peng H, Katsnelson J, Yang W, Kaplan N, Dong Y, Rappoport JZ, He C, Lavker RM. MicroRNAs-103/107 coordinately regulate macropinocytosis and autophagy. Journal of Cell Biology. 2016 Dec 05;215(5):667-685.

Williamson SC, Metcalf RL, Trapani F, Mohan S, Antonello J, Abbott B, Leong HS, Chester CPE, Simms N, Polanski R, Nonaka D, Priest L, Fusi A, Carlsson F, Carlsson A, Hendrix MJC, Seftor REB, Seftor EA, Rothwell DG, Hughes A, Hicks J, Miller C, Kuhn P, Brady G, Simpson KL, Blackhall FH, Dive C. Vasculogenic mimicry in small cell lung cancer. Nature Communications. 2016 Nov;7:14.

Zeng XH, Duch J, Sales-Pardo M, Moreira JA, Radicchi F, Ribeiro HV, Woodruff TK, Amaral LA. Differences in Collaboration Patterns across Discipline, Career Stage, and Gender. PLoS Biology. 2016 Nov;14(11):e1002573.

Zhao SG, Chang SL, Spratt DE, Erho N, Yu M, Ashab HA, Alshalalfa M, Speers C, Tomlins SA, Davicioni E, Dicker AP, Carroll PR, Cooperberg MR, Freedland SJ, Karnes RJ, Ross AE, Schaeffer EM, Den RB, Nguyen PL, Feng FY. Development and validation of a 24-gene predictor of response to postoperative radiotherapy in prostate cancer: a matched, retrospective analysis. Lancet Oncology. 2016 Nov;17(11):1612-1620.

Almassalha LM, Bauer GM, Chandler JE, Gladstein S, Cherkezyan L, Stypula-Cyrus Y, Weinberg S, Zhang D, Thusgaard Ruhoff P, Roy HK, Subramanian H, Chandel NS, Szleifer I, Backman V. Label-free imaging of the native, living cellular nanoarchitecture using partial-wave spectroscopic microscopy. Proceedings of the National Academy of Sciences of the United States of America. 2016 Oct 18;113(42):E6372-e6381.

Brinkman TM, Li CH, Vannatta K, Marchak JG, Lai JS, Prasad PK, Kimberg C, Vuotto S, Di CZ, Srivastava D, Robison LL, Armstrong GT, Krull KR. Behavioral, Social, and Emotional Symptom Comorbidities and Profiles in Adolescent Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study. Journal of Clinical Oncology. 2016 Oct;34(28):3417.

Escobedo N, Oliver G. Lymphangiogenesis: Origin, Specification, and Cell Fate Determination. Annual Review of Cell and Developmental Biology. 2016 Oct 6;32:677-691.

Furlan A, La Manno G, Lubke M, Haring M, Abdo H, Hochgerner H, Kupari J, Usoskin D, Airaksinen MS, Oliver G, Linnarsson S, Ernfors P. Visceral motor neuron diversity delineates a cellular basis for nipple- and pilo-erection muscle control. Nature Neuroscience. 2016 Oct;19(10):1331.

Hivert MF, Arena R, Forman DE, Kris-Etherton PM, McBride PE, Pate RR, Spring B, Trilk J, Van Horn LV, Kraus WE, Council Lifestyle Cardiometab H, Behav Change C, Council Clin C, Council Cardiovasc Stroke N. Medical Training to Achieve Competency in Lifestyle Counseling: An Essential Foundation for Prevention and Treatment of Cardiovascular Diseases and Other Chronic Medical Conditions: A Scientific Statement From the American Heart Association. Circulation. 2016 Oct;134(15):E308-E327.

Horikoshi M, Beaumont RN, Day FR, et al. (including: Scholtens DM, Lowe WL). Genome-wide associations for birth weight and correlations with adult disease. Nature. 2016 Oct;538(7624):248.

Huang T, Alvarez AA, Pangeni RP, Horbinski CM, Lu S, Kim SH, James CD, Raiszer JJ, Kessler JA, Brenann CW, Sulman EP, Finocchiaro G, Tan M, Nishikawa R, Lu X, Nakano I, Hu B, Cheng SY. A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways. Nat Communication. 2016 Oct 04;7:12885.

Kagan CR, Fernandez LE, Gogotsi Y, Hammond PT, Hersam MC, Nel AE, Penner RM, Willson CG, Weiss PS. Nano Day: Celebrating the Next Decade of Nanoscience and Nanotechnology. ACS Nano. 2016 Oct;10(10):9093-9103.

Kang J, Wells SA, Wood JD, Lee JH, Liu X, Ryder CR, Zhu J, Guest JR, Husko CA, Hersam MC. Stable aqueous dispersions of optically and electronically active phosphorene. Proceedings of the National Academy of Sciences of the United States of America. 2016 Oct 18;113(42):11688-11693.

Liu C, Kraja AT, Smith JA, et al. (including Lu K). Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci. Nature Genetics. 2016 Oct;48(10):1162-1170.

Mathias RA, Taub MA, Gignoux CR, et al. (including Kumar R, Avila PC, Schleimer R, Grammer L, Kim KY). A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome. Nature Communications. 2016 Oct 11;7:12522.

O'Brien MN, Jones MR, Mirkin CA. The nature and implications of uniformity in the hierarchical organization of nanomaterials. Proceedings of the National Academy of Sciences of the United States of America. 2016 Oct 18;113(42):11717-11725.

Shen PS, Yang X, DeCaen PG, Liu X, Bulkley D, Clapham DE, Cao E. The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs. Cell. 2016 Oct 20;167(3):763-773.e711.

Swiryn S, Orlov MV, Benditt DG, DiMarco JP, Lloyd-Jones DM, Karst E, Qu F, Slawsky MT, Turkel M, Waldo AL. Clinical Implications of Brief Device-Detected Atrial Tachyarrhythmias in a Cardiac Rhythm Management Device Population: Results from the Registry of Atrial Tachycardia and Atrial Fibrillation Episodes. Circulation. 2016 Oct 18;134(16):1130-1140.

Tetreault P, Mansour A, Vachon-Presseau E, Schnitzer TJ, Apkarian AV, Baliki MN. Brain Connectivity Predicts Placebo Response across Chronic Pain Clinical Trials. PLoS Biology. 2016 Oct;14(10):e1002570.

Yoo YA, Roh M, Naseem AF, Lysy B, Desouki MM, Unno K, Abdulkadir SA. Bmi1 marks distinct castration-resistant luminal progenitor cells competent for prostate regeneration and tumour initiation. Nature Communications. 2016 Oct 05;7:12943.

Alhasan AH, Scott AW, Wu JJ, Feng G, Meeks JJ, Thaxton CS, Mirkin CA. Circulating microRNA signature for the diagnosis of very high-risk prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 2016 Sep 20;113(38):10655-10660.

Braun LT, Grady KL, Kutner JS, Adler E, Berlinger N, Boss R, Butler J, Enguidanos S, Friebert S, Gardner TJ, Higgins P, Holloway R, Konig M, Meier D, Morrissey MB, Quest TE, Wiegand DL, Coombs-Lee B, Fitchett G, Gupta C, Roach WH, Amer Heart Assoc Advocacy C. Palliative Care and Cardiovascular Disease and Stroke A Policy Statement From the American Heart Association/American Stroke Association. Circulation. 2016 Sep;134(11):E198-E225.

Brisson GE, Tyler PD. Medical Student Use of Electronic Health Records to Track Former Patients. JAMA Intern Medicine. 2016 Sep 1;176(9):1395-1397.

http://www.ncbi.nlm.nih.gov/pubmed/27454543

Gratias EJ, Dome JS, Jennings LJ, Chi YY, Tian J, Anderson J, Grundy P, Mullen EA, Geller JI, Fernandez CV, Perlman EJ. Association of Chromosome 1q Gain With Inferior Survival in Favorable-Histology Wilms Tumor: A Report From the Children's Oncology Group. Journal of Clinical Oncology. 2016 Sep;34(26):3189.

Higgins SJ, Purcell LA, Silver KL, Tran V, Crowley V, Hawkes M, Conroy AL, Opoka RO, Hay JG, Quaggin SE, Thurston G, Liles WC, Kain KC. Dysregulation of angiopoietin-1 plays a mechanistic role in the pathogenesis of cerebral malaria. Science Translational Medicine. 2016 Sep 28;8(358):358ra128.

Hu DQ, Shilatifard A. Epigenetics of hematopoiesis and hematological malignancies. Genes & Development. 2016 Sep;30(18):2021-2041. 

Jakus AE, Rutz AL, Jordan SW, Kannan A, Mitchell SM, Yun C, Koube KD, Yoo SC, Whiteley HE, Richter CP, Galiano RD, Hsu WK, Stock SR, Hsu EL, Shah RN. Hyperelastic "bone": A highly versatile, growth factor-free, osteoregenerative, scalable, and surgically friendly biomaterial. Science Translational Medicine. 2016 Sep 28;8(358):358ra127.

Kong SY, Yang Y, Xu YM, Wang YJ, Zhang YS, Melo-Cardenas J, Xu XP, Gao BX, Thorp EB, Zhang DD, Zhang B, Song JX, Zhang KZ, Zhang JN, Zhang JP, Li HB, Fang DY. Endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 controls B-cell immunity through degradation of the death receptor CD95/Fas. Proceedings of the National Academy of Sciences of the United States of America. 2016 Sep;113(37):10394-10399.

Matsa E, Burridge PW, Yu KH, Ahrens JH, Termglinchan V, Wu H, Liu C, Shukla P, Sayed N, Churko JM, Shao N, Woo NA, Chao AS, Gold JD, Karakikes I, Snyder MP, Wu JC. Transcriptome Profiling of Patient-Specific Human iPSC-Cardiomyocytes Predicts Individual Drug Safety and Efficacy Responses In Vitro. Cell Stem Cell. 2016 Sep 1;19(3):311-325.

Muller WA. Transendothelial migration: unifying principles from the endothelial perspective. Immunological Reviews. 2016 Sep;273(1):61-75.

Ntziachristos P, Abdel-Wahab O, Aifantis I. Emerging concepts of epigenetic dysregulation in hematological malignancies. Nature Immunology. 2016 Sep;17(9):1016-1024.

O'Brien MN, Girard M, Lin HX, Millan JA, Olvera de la Cruz M, Lee B, Mirkin CA. Exploring the zone of anisotropy and broken symmetries in DNA-mediated nanoparticle crystallization. Proceedings of the National Academy of Sciences of the United States of America. 2016 Sep 20;113(38):10485-10490.

O'Connell PJ, Zhang WJ, Menon MC, Yi ZZ, Schroppel B, Gallon L, Luan Y, Rosales IA, Ge YC, Losic B, Xi CX, Woytovich C, Keung KL, Wei CG, Greene I, Overbey J, Bagiella E, Najafian N, Samaniego M, Djamali A, Alexander SI, Nankivell BJ, Chapman JR, Smith RN, Colvin R, Murphy B. Biopsy transcriptome expression profiling to identify kidney transplants at risk of chronic injury: a multicentre, prospective study. Lancet. 2016 Sep;388(10048):983-993.

Paice JA, Portenoy R, Lacchetti C, Campbell T, Cheville A, Citron M, Constine LS, Cooper A, Glare P, Keefe F, Koyyalagunta L, Levy M, Miaskowski C, Otis-Green S, Sloan P, Bruera E. Management of Chronic Pain in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline. Journal of Clinical Oncology. 2016 Sep 20;34(27):3325-3345.

Piochon C, Kano M, Hansel C. LTD-like molecular pathways in developmental synaptic pruning. Nature Neuroscience. 2016 Sep 27;19(10):1299-1310.

Steinberger J, Daniels SR, Hagberg N, Isasi CR, Kelly AS, Lloyd-Jones D, Pate RR, Pratt C, Shay CM, Towbin JA, Urbina E, Van Horn LV, Zachariah JP, Amer Heart Assoc A, Council Cardiovasc Stroke N, Council Epidemiology P, Council Functional G, Stroke C. Cardiovascular Health Promotion in Children: Challenges and Opportunities for 2020 and Beyond A Scientific Statement From the American Heart Association. Circulation. 2016 Sep;134(12):E236-E255.

Varvel NH, Neher JJ, Bosch A, Wang W, Ransohoff RM, Miller RJ, Dingledine R. Infiltrating monocytes promote brain inflammation and exacerbate neuronal damage after status epilepticus. Proceedings of the National Academy of Sciences of the United States of America. 2016 Sep 20;113(38):E5665-5674.

Yanik EL, Achenbach CJ, Gopal S, Coghill AE, Cole SR, Eron JJ, Moore RD, Mathews WC, Drozd DR, Hamdan A, Ballestas ME, Engels EA. Changes in Clinical Context for Kaposi's Sarcoma and Non-Hodgkin Lymphoma Among People With HIV Infection in the United States. Journal of Clinical Oncology. 2016 Sep 20;34(27):3276-3283.

Beguelin W, Teater M, Gearhart MD, Calvo Fernandez MT, Goldstein RL, Cardenas MG, Hatzi K, Rosen M, Shen H, Corcoran CM, Hamline MY, Gascoyne RD, Levine RL, Abdel-Wahab O, Licht JD, Shaknovich R, Elemento O, Bardwell VJ, Melnick AM. EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis. Cancer Cell. 2016 Aug 8;30(2):197-213. 

Chandel NS, Jasper H, Ho TT, Passegue E. Metabolic regulation of stem cell function in tissue homeostasis and organismal ageing. Nature Cell Biology. 2016 Aug;18(8):823-832.

Dong B, Almassalha LM, Stypula-Cyrus Y, Urban BE, Chandler JE, Nguyen TQ, Sun C, Zhang HF, Backman V. Superresolution intrinsic fluorescence imaging of chromatin utilizing native, unmodified nucleic acids for contrast. Proceedings of the National Academy of Sciences of the United States of America. 2016 Aug 30;113(35):9716-9721.

Enzinger PC, Burtness BA, Niedzwiecki D, Ye X, Douglas K, Ilson DH, Villaflor VM, Cohen SJ, Mayer RJ, Venook A, Benson AB, 3rd, Goldberg RM. CALGB 80403 (Alliance)/E1206: A Randomized Phase II Study of Three Chemotherapy Regimens Plus Cetuximab in Metastatic Esophageal and Gastroesophageal Junction Cancers. Journal of Clinical Oncology. 2016 Aug 10;34(23):2736-2742.

Germain DP, Hughes DA, Nicholls K, Bichet DG, Giugliani R, Wilcox WR, Feliciani C, Shankar SP, Ezgu F, Amartino H, Bratkovic D, Feldt-Rasmussen U, Nedd K, Sharaf El Din U, Lourenco CM, Banikazemi M, Charrow J, Dasouki M, Finegold D, Giraldo P, Goker-Alpan O, Longo N, Scott CR, Torra R, Tuffaha A, Jovanovic A, Waldek S, Packman S, Ludington E, Viereck C, Kirk J, Yu J, Benjamin ER, Johnson F, Lockhart DJ, Skuban N, Castelli J, Barth J, Barlow C, Schiffmann R. Treatment of Fabry's Disease with the Pharmacologic Chaperone Migalastat. New England Journal of Medicine. 2016 Aug 11;375(6):545-555.

Hess PL, Hernandez AF, Bhatt DL, Hellkamp AS, Yancy CW, Schwamm LH, Peterson ED, Schulte PJ, Fonarow GC, Al-Khatib SM. Sex and Race/Ethnicity Differences in Implantable Cardioverter-Defibrillator Counseling and Use Among Patients Hospitalized With Heart Failure: Findings from the Get With The Guidelines-Heart Failure Program. Circulation. 2016 Aug 16;134(7):517-526.

Kaufman JD, Adar SD, Barr RG, Budoff M, Burke GL, Curl CL, Daviglus ML, Diez Roux AV, Gassett AJ, Jacobs DR, Jr., Kronmal R, Larson TV, Navas-Acien A, Olives C, Sampson PD, Sheppard L, Siscovick DS, Stein JH, Szpiro AA, Watson KE. Association between air pollution and coronary artery calcification within six metropolitan areas in the USA (the Multi-Ethnic Study of Atherosclerosis and Air Pollution): a longitudinal cohort study. Lancet. 2016 Aug 13;388(10045):696-704.

Lu W, Winding M, Lakonishok M, Wildonger J, Gelfand VI. Microtubule-microtubule sliding by kinesin-1 is essential for normal cytoplasmic streaming in Drosophila oocytes. Proceedings of the National Academy of Sciences of the United States of America. 2016 Aug 23;113(34):E4995-5004.

Mahajan P, Kuppermann N, Mejias A, Suarez N, Chaussabel D, Casper TC, Smith B, Alpern ER, Anders J, Atabaki SM, Bennett JE, Blumberg S, Bonsu B, Borgialli D, Brayer A, Browne L, Cohen DM, Crain EF, Cruz AT, Dayan PS, Gattu R, Greenberg R, Hoyle JD, Jr., Jaffe DM, Levine DA, Lillis K, Linakis JG, Muenzer J, Nigrovic LE, Powell EC, Rogers AJ, Roosevelt G, Ruddy RM, Saunders M, Tunik MG, Tzimenatos L, Vitale M, Dean JM, Ramilo O. Association of RNA Biosignatures With Bacterial Infections in Febrile Infants Aged 60 Days or Younger. JAMA. 2016 Aug 23-30;316(8):846-857.

Martinez-Picado J, McLaren PJ, Erkizia I, Martin MP, Benet S, Rotger M, Dalmau J, Ouchi D, Wolinsky SM, Penugonda S, Gunthard HF, Fellay J, Carrington M, Izquierdo-Useros N, Telenti A. Identification of Siglec-1 null individuals infected with HIV-1. Nature Communications. 2016;7:12412.

Nadadur RD, Broman MT, Boukens B, Mazurek SR, Yang X, van den Boogaard M, Bekeny J, Gadek M, Ward T, Zhang M, Qiao Y, Martin JF, Seidman CE, Seidman J, Christoffels V, Efimov IR, McNally EM, Weber CR, Moskowitz IP. Pitx2 modulates a Tbx5-dependent gene regulatory network to maintain atrial rhythm. Science Translational Medicine. 2016 Aug 31;8(354):354ra115.

Poulin JF, Tasic B, Hjerling-Leffler J, Trimarchi JM, Awatramani R. Disentangling neural cell diversity using single-cell transcriptomics. Nature Neuroscience. 2016 Aug 26;19(9):1131-1141.

Preslar AT, Tantakitti F, Park K, Zhang S, Stupp SI, Meade TJ. (19)F Magnetic Resonance Imaging Signals from Peptide Amphiphile Nanostructures Are Strongly Affected by Their Shape. ACS Nano. 2016 Aug 23;10(8):7376-7384.

Pritchard CC, Mateo J, Walsh MF, De Sarkar N, Abida W, Beltran H, Garofalo A, Gulati R, Carreira S, Eeles R, Elemento O, Rubin MA, Robinson D, Lonigro R, Hussain M, Chinnaiyan A, Vinson J, Filipenko J, Garraway L, Taplin ME, AlDubayan S, Han GC, Beightol M, Morrissey C, Nghiem B, Cheng HH, Montgomery B, Walsh T, Casadei S, Berger M, Zhang L, Zehir A, Vijai J, Scher HI, Sawyers C, Schultz N, Kantoff PW, Solit D, Robson M, Van Allen EM, Offit K, de Bono J, Nelson PS. Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer. New England Journal of Medicine. 2016 Aug;375(5):443-453.

Wei HS, Kang H, Rasheed IY, Zhou S, Lou N, Gershteyn A, McConnell ED, Wang Y, Richardson KE, Palmer AF, Xu C, Wan J, Nedergaard M. Erythrocytes Are Oxygen-Sensing Regulators of the Cerebral Microcirculation. Neuron. 2016 Aug 17;91(4):851-862.

Winding M, Kelliher MT, Lu W, Wildonger J, Gelfand VI. Role of kinesin-1-based microtubule sliding in Drosophila nervous system development. Proceedings of the National Academy of Sciences of the United States of America. 2016 Aug 23;113(34):E4985-4994.

Blizinsky KD, Diaz-Castro B, Forrest MP, Schurmann B, Bach AP, Martin-de-Saavedra MD, Wang L, Csernansky JG, Duan J, Penzes P. Reversal of dendritic phenotypes in 16p11.2 microduplication mouse model neurons by pharmacological targeting of a network hub. Proceedings of the National Academy of Sciences of the United States of America. 2016 Jul 26;113(30):8520-8525.

Cella D, Grunwald V, Nathan P, Doan J, Dastani H, Taylor F, Bennett B, DeRosa M, Berry S, Broglio K, Berghorn E, Motzer RJ. Quality of life in patients with advanced renal cell carcinoma given nivolumab versus everolimus in CheckMate 025: a randomised, open-label, phase 3 trial. Lancet Oncology. 2016 Jul;17(7):994-1003.

Deng HX, Shi Y, Yang Y, Ahmeti KB, Miller N, Huang C, Cheng L, Zhai H, Deng S, Nuytemans K, Corbett NJ, Kim MJ, Deng H, Tang B, Yang Z, Xu Y, Chan P, Huang B, Gao XP, Song Z, Liu Z, Fecto F, Siddique N, Foroud T, Jankovic J, Ghetti B, Nicholson DA, Krainc D, Melen O, Vance JM, Pericak-Vance MA, Ma YC, Rajput AH, Siddique T. Identification of TMEM230 mutations in familial Parkinson's disease. Nature Genetics. 2016 Jul;48(7):733-739.

Dong B, Almassalha L, Urban BE, Nguyen TQ, Khuon S, Chew TL, Backman V, Sun C, Zhang HF. Super-resolution spectroscopic microscopy via photon localization. Nat Communications. 2016;7:12290.

Dorfleutner A, Stehlik C. A dRAStic RHOAdblock of Pyrin inflammasome activation. Nature Immunology. 2016 Jul 19;17(8):900-902.

Dua KS, Hogan WJ, Aadam AA, Gasparri M. In-vivo oesophageal regeneration in a human being by use of a non-biological scaffold and extracellular matrix. Lancet. 2016 Jul;388(10039):55-61.

Gordon KB, Blauvelt A, Papp KA, Langley RG, Luger T, Ohtsuki M, Reich K, Amato D, Ball SG, Braun DK, Cameron GS, Erickson J, Konrad RJ, Muram TM, Nickoloff BJ, Osuntokun OO, Secrest RJ, Zhao F, Mallbris L, Leonardi CL. Phase 3 Trials of Ixekizumab in Moderate-to-Severe Plaque Psoriasis. New England Journal of Medicine. 2016 Jul 28;375(4):345-356.

Grabner CP, Ratliff CP, Light AC, DeVries SH. Mechanism of High-Frequency Signaling at a Depressing Ribbon Synapse. Neuron. 2016 Jul 6;91(1):133-145.

Herrmann HC, Thourani VH, Kodali SK, Makkar RR, Szeto WY, Anwaruddin S, Desai N, Lim S, Malaisrie SC, Kereiakes DJ, Ramee S, Greason KL, Kapadia S, Babaliaros V, Hahn RT, Pibarot P, Weissman NJ, Leipsic J, Whisenant BK, Webb JG, Mack MJ, Leon MB. One-Year Clinical Outcomes With SAPIEN 3 Transcatheter Aortic Valve Replacement in High-Risk and Inoperable Patients With Severe Aortic Stenosis. Circulation. 2016 Jul 12;134(2):130-140.

Kay-Stacey M, Attarian H. Advances in the management of chronic insomnia. BMJ. 2016;354:i2123.

Lee S, Shang Y, Redmond SA, Urisman A, Tang AA, Li KH, Burlingame AL, Pak RA, Jovicic A, Gitler AD, Wang J, Gray NS, Seeley WW, Siddique T, Bigio EH, Lee VM, Trojanowski JQ, Chan JR, Huang EJ. Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis. Neuron. 2016 Jul 6;91(1):41-55.

Li S, Heller JJ, Bostick JW, Lee A, Schjerven H, Kastner P, Chan S, Chen ZE, Zhou L. Ikaros Inhibits Group 3 Innate Lymphoid Cell Development and Function by Suppressing the Aryl Hydrocarbon Receptor Pathway. Immunity. 2016 Jul 19;45(1):185-197.

Minami CA, Stulberg JJ, Hungness ES. Partnering Behavioral Modification With Bariatric Surgery. JAMA. 2016 Jul 26;316(4):448-449.

O'Brien MJ, Lee JY, Carnethon MR, Ackermann RT, Vargas MC, Hamilton A, Mohanty N, Rittner SS, Park JN, Hassan A, Buchanan DR, Liu L, Feinglass J. Detecting Dysglycemia Using the 2015 United States Preventive Services Task Force Screening Criteria: A Cohort Analysis of Community Health Center Patients. PLoS Medicine. 2016 Jul;13(7):e1002074.

Perak AM, Ning H, de Ferranti SD, Gooding HC, Wilkins JT, Lloyd-Jones DM. Long-Term Risk of Atherosclerotic Cardiovascular Disease in US Adults With the Familial Hypercholesterolemia Phenotype. Circulation. 2016 Jul;134(1):9.

Ramkumar P, Acuna DE, Berniker M, Grafton ST, Turner RS, Kording KP. Chunking as the result of an efficiency computation trade-off. Nat Communications. 2016;7:12176.

Rickels R, Hu D, Collings CK, Woodfin AR, Piunti A, Mohan M, Herz HM, Kvon E, Shilatifard A. An Evolutionary Conserved Epigenetic Mark of Polycomb Response Elements Implemented by Trx/MLL/COMPASS. Molecular Cell. 2016 Jul 21;63(2):318-328.

Shah SJ, Kitzman DW, Borlaug BA, van Heerebeek L, Zile MR, Kass DA, Paulus WJ. Phenotype-Specific Treatment of Heart Failure With Preserved Ejection Fraction A Multiorgan Roadmap. Circulation. 2016 Jul;134(1):73.

Song AS, Poor TA, Abriata LA, Jardetzky TS, Dal Peraro M, Lamb RA. Immobilization of the N-terminal helix stabilizes prefusion paramyxovirus fusion proteins. Proceedings of the National Academy of Sciences of the United States of America. 2016 Jul 5;113(27):E3844-3851.

Xu Y, Zhao F, Qiu Q, Chen K, Wei J, Kong Q, Gao B, Melo-Cardenas J, Zhang B, Zhang J, Song J, Zhang DD, Zhang J, Fan Y, Li H, Fang D. The ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator of T-cell immunity. Nat Communications. 2016;7:12073.

Burt RK, Ruiz MA, Kaiser RL, Jr. Stem Cell Transplantation for Refractory Crohn Disease. JAMA. 2016 Jun 21;315(23):2620.

Badal SS, Wang Y, Long J, Corcoran DL, Chang BH, Truong LD, Kanwar YS, Overbeek PA, Danesh FR. miR-93 regulates Msk2-mediated chromatin remodeling in diabetic nephropathy. Nature Communications. 2016;7:12076.

Bhattacharyya S, Wang WX, Morales-Nebreda L, Feng G, Wu MH, Zhou XD, Lafyatis R, Lee J, Hinchcliff M, Feghali-Bostwick C, Lakota K, Budinger GRS, Raparia K, Tamaki Z, Varga J. Tenascin-C drives persistence of organ fibrosis. Nature Communications. 2016 Jun;7:14.

Cai BS, Thorp EB, Doran AC, Subramanian M, Sansbury BE, Lin CS, Spite M, Fredman G, Tabas I. MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation. Proceedings of the National Academy of Sciences of the United States of America. 2016 Jun;113(23):6526-6531.

Chen PC, Liu X, Hedrick JL, Xie Z, Wang S, Lin QY, Hersam MC, Dravid VP, Mirkin CA. Polyelemental nanoparticle libraries. Science. 2016 Jun 24;352(6293):1565-1569.

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Tantakitti F, Boekhoven J, Wang X, Kazantsev RV, Yu T, Li JH, Zhuang E, Zandi R, Ortony JH, Newcomb CJ, Palmer LC, Shekhawat GS, de la Cruz MO, Schatz GC, Stupp SI. Energy landscapes and functions of supramolecular systems. Nature Materials. 2016 Apr;15(4):469.

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Velazquez EJ, Lee KL, Jones RH, Al-Khalidi HR, Hill JA, Panza JA, Michler RE, Bonow RO, Doenst T, Petrie MC, Oh JK, She L, Moore VL, Desvigne-Nickens P, Sopko G, Rouleau JL. Coronary-Artery Bypass Surgery in Patients with Ischemic Cardiomyopathy. New England Journal of Medicine. 2016 Apr 21;374(16):1511-1520.

Wei W, Shin YS, Xue M, Matsutani T, Masui K, Yang HJ, Ikegami S, Gu YC, Herrmann K, Johnson D, Ding XM, Hwang K, Kim J, Zhou J, Su YP, Li XM, Bonetti B, Chopra R, James CD, Cavenee WK, Cloughesy TF, Mischel PS, Heath JR, Gini B. Single-Cell Phosphoproteomics Resolves Adaptive Signaling Dynamics and Informs Targeted Combination Therapy in Glioblastoma. Cancer Cell. 2016 Apr;29(4):563-573.

Zasadzinska E, Foltz DR. Centromeres of a Different CAL-ibre. Developmental Cell. 2016 Apr 18;37(2):105-106.

Zunke F, Andresen L, Wesseler S, Groth J, Arnold P, Rothaug M, Mazzulli JR, Krainc D, Blanz J, Saftig P, Schwake M. Characterization of the complex formed by beta-glucocerebrosidase and the lysosomal integral membrane protein type-2. Proceedings of the National Academy of Sciences of the United States of America. 2016 Apr;113(14):3791-3796.

Blaha MJ, Cainzos-Achirica M, Greenland P, McEvoy JW, Blankstein R, Budoff MJ, Dardari Z, Sibley CT, Burke GL, Kronmal RA, Szklo M, Blumenthal RS, Nasir K. Role of Coronary Artery Calcium Score of Zero and Other Negative Risk Markers for Cardiovascular Disease The Multi-Ethnic Study of Atherosclerosis (MESA). Circulation. 2016 Mar;133(9):849-858.

Blum CB, Stone NJ. New Strategies to Treat High Cholesterol. JAMA-Journal of the American Medical Association. 2016 Mar;315(11):1169-1169.

Bonow RO, Leon MB, Doshi D, Moat N. Management strategies and future challenges for aortic valve disease. Lancet 2016 Mar 26;387(10025):1312-1323.

Chen YH, Li Y, Xue JF, Gong AH, Yu GZ, Zhou AD, Lin KY, Zhang SC, Zhang N, Gottardi CJ, Huang SY. Wnt-induced deubiquitination FoxM1 ensures nucleus beta-catenin transactivation. EMBO Journal. 2016 Mar;35(6):668-684.

Chun HJ, Lim EL, Heravi-Moussavi A, Saberi S, Mungall KL, Bilenky M, Carles A, Tse K, Shlafman I, Zhu K, Qian JQ, Palmquist DL, He A, Long W, Goya R, Ng M, LeBlanc VG, Pleasance E, Thiessen N, Wong T, Chuah E, Zhao YJ, Schein JE, Gerhard DS, Taylor MD, Mungall AJ, Moore RA, Ma Y, Jones SJ, Perlman EJ, Hirst M, Marra MA. Genome-Wide Profiles of Extra-cranial Malignant Rhabdoid Tumors Reveal Heterogeneity and Dysregulated Developmental Pathways. Cancer Cell. 2016 Mar 14;29(3):394-406.

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Lay K, Kume T, Fuchs E. FOXC1 maintains the hair follicle stem cell niche and governs stem cell quiescence to preserve long-term tissue-regenerating potential. Proceedings of the National Academy of Sciences of the United States of America. 2016 Mar;113(11):E1506-E1525.

Nardi IK, Zasadzinska E, Stellfox ME, Knippler CM, Foltz DR. Licensing of Centromeric Chromatin Assembly through the Mis18alpha-Mis18beta Heterotetramer. Molecular Cell. 2016 Mar 3;61(5):774-787.

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