Events

Please complete this form to add an event to the medical school calendar. All events added to the medical school calendar will also be added to our digital monitor event feeds. Up to three calendar entries will be selected weekly to appear as full-screen slides.

Nov

TEAM/SBDRC Seminar: Improving PD-1 Therapy with Viral Vaccines

Chicago - 12:00 PM - 1:00 PM

The Robert H. Lurie Comprehensive Cancer Center of Northwestern University's TEAM Program and Northwestern's Skin Biology and Diseases Resource-Based Center present:

Improving PD-1 Therapy with Viral Vaccines

Pablo Penaloza-MacMaster, PhD
Assistant Professor of Microbiology-Immunology
Northwestern University Feinberg School of Medicine

Refreshments will be provided.

Nov

"Tongue Kinematics. Cortex-dependent corrections as the mouse tongue reaches for, and misses, targets"

Chicago - 12:00 PM - 1:00 PM

The department of Physiology welcomes Jesse Goldberg, M.D., Ph.D.

Precise control of the tongue is necessary for drinking, eating, and vocalizing. Yet because tongue movements are fast and difficult to resolve, neural control of lingual kinematics remains poorly understood. We combine kilohertz frame-rate imaging and a deep-learning based artificial neural network to resolve 3D tongue kinematics in mice performing a cued lick task. Cue-evoked licks exhibit previously unobserved fine-scale movements which, like a hand searching for an unseen object, were produced after misses and were directionally biased towards remembered locations. Photoinhibition of anterolateral motor cortex (ALM) abolished these fine-scale adjustments, resulting in well-aimed but hypometric licks that missed the spout. Our results show that cortical activity is required for online corrections during licking and reveal novel, limb-like dynamics of the mouse tongue as it reaches for, and misses, targets.

Nov

Nathaniel Berlin Lectureship: Modeling Tumor Immunity from RNA-seq

Chicago - 3:30 PM - 4:30 PM

The Robert H. Lurie Comprehensive Cancer Center of Northwestern University and the DGP Lectures in Life Sciences Series present the Nathaniel Berlin Lectureship:

Modeling Tumor Immunity from RNA-seq

Xiaole Shirley Liu, PhD
Professor, Biostatistics, Harvard T.H. Chan School Of Public Health
Co-director, Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute

Host: Jindan Yu, MD, PhD

Light refreshments provided.

The Nathaniel Berlin Lectureship is held to honor Nathaniel I. Berlin, MD, PhD, a pioneer in cancer research who served as director of the Lurie Cancer Center from its founding until his retirement in 1987.

Nov

"Using Developmental Pathways to Stimulate Organ Regeneration" FCVRRI Lectureship

Chicago - 4:00 PM - 5:00 PM

Presented By:

Kristy Red-Horse, PhD

Associate Professor
Department of Biology
Stanford University

Feinberg Cardiovascular & Renal Research Institute

Nov

IPHAM Seminar Series: "System Strategies for Balancing Comfort and Patient Safety in the Opioid Era"

Chicago - 12:00 PM - 1:00 PM

Title: "System Strategies for Balancing Comfort and Patient Safety in the Opioid Era"

Speaker: Rachel Seymour, PhD

Vice Chair for Research and Professor

Department of Orthopaedic Surgery

Atrium Health Musculoskeletal Institute

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THURSDAYS AT NOON

Every Thursday during the academic year, IPHAM hosts a public health-focused seminar, which is also available via live stream

Engaging speakers; relevant research; CME credit

Join us in person at Baldwin Auditorium (unless otherwise noted), Robert H. Lurie Medical Research Center (303 E. Superior; Chicago, IL)

Nov

“New tools to record neuronal network dynamics in models of disease.”

Chicago - 12:00 PM - 1:00 PM

The department of Physiology welcomes Peyman Golshani, Ph.D.

We have developed new open-source miniaturized microscopy tools to to record neuronal dynamics in freely behaving animals. These tools include wireless miniaturized microscopes, large-field of view scopes, light field miniaturized microscopes for 3-dimensional imaging, multichannel miniaturized microscopes, and microscopes integrated with multichannel electrophysiology. These tools are being shared with the community through miniscope.org as they are each finalized. We have used some of these tools to record network dynamics in the hippocampus of a temporal lobe models of epilepsy. We have found dramatic imprecision and instability of place cells in these models.

Nov

Women's Forum

Chicago - 12:00 PM - 1:00 PM

Women s Forum is an event sponsored by Northwestern s Medical Scientist Training Program that intends to highlight the distinct experiences and challenges that women face as physician scientists, both while they are in training and once they have begun their careers. Furthermore, it is also meant to celebrate women who have succeeded despite disadvantage. Everyone is welcome, as we believe that a diversity of perspectives is beneficial to everyone!

Dr. Jagsi's Bio: http://bit.ly/WomensForum_Jagsi

Nov

Basic Research Seminar: The Regulation of the Heat Shock Response in C. elegans

Chicago - 11:30 AM - 12:30 PM

The Basic Research Seminar Series of the Robert H. Lurie Comprehensive Cancer of Northwestern University presents:

The Regulation of the Heat Shock Response in C. elegans

Sandy Westerheide, PhD
Associate Professor
Department of Cell Biology, Microbiology and Molecular Biology
University of South Florida

Host: Robin Leikin, PhD

Light lunch provided.

The Basic Research Seminar series presents prominent basic science speakers weekly to inspire and promote ongoing cancer research at Northwestern University.

Dec

Basic Research Seminar: EphA2 RTK, Glutamine Metabolism, and Anti-Tumor Immunity

Chicago - 11:30 AM - 12:30 PM

The Basic Research Seminar Series of the Robert H. Lurie Comprehensive Cancer of Northwestern University presents:

EphA2 RTK, Glutamine Metabolism, and Anti-Tumor Immunity

Jin Chen, MD, PhD
Professor of Medicine, Division of Rheumatology & Immunology
Professor of Cancer Biology
Professor of Cell & Developmental Biology
Vanderbilt University

Host: Yong Wan, PhD

Light lunch provided.

The Basic Research Seminar series presents prominent basic science speakers weekly to inspire and promote ongoing cancer research at Northwestern University.

Dec

Department of Microbiology-Immunology: J. Victor Garcia-Martinez, PhD

Chicago - 12:00 PM - 1:00 PM

Title: Next Generation Precision Animal Models for Biomedical Research

Speaker: J. Victor Garcia-Martinez, PhD

Host: Mojgan Naghavi,phD

Topic:

The applications of current humanized mouse models for biomedical research would be significantly broadened by the inclusion of human non-hematopoietic cell types, the primary targets of most human pathogens, that can present antigen to autologous human immune cells in the full context of HLA. When epithelial, endothelial, mesenchymal and smooth muscle cells are incorporated into humanized BLT mice, emerging and clinically relevant human pathogens such as Middle East respiratory syndrome coronavirus, Zika virus, respiratory syncytial virus, and cytomegalovirus replicate in vivo in these models. Direct inoculation of the model with HCMV induces HCMV-specific human IgM, IgG and T cell responses that can effectively control infection in vivo. These new models can be used to study pathogen replication, pathogenesis, immune reactivity and human therapies in the context of a fully functional human immune system.

Dec

IPHAM Population Health Forum

Chicago - 9:00 AM - 1:30 PM

Second annual Institute for Public Health and Medicine (IPHAM) Population Health Forum and Poster Session
Monday, December 9, 2019
9:00 a.m. 2:00 p.m.
Robert H. Lurie Medical Research Center
303 East Superior Street
Hughes Auditorium

RSVP ONLINE

KEYNOTE SPEAKER:
Ana V. Diez Roux, MD, PhD, MPH
Dean and Distinguished University Professor of Epidemiology
Director, Urban Health Collaborative
Dornsife School of Public Health, Drexel University

SCHEDULE:
9:00 10:30 a.m. Forum and Panel
10:30 a.m. 12:00 p.m. Poster Session
12:00 1:30 p.m. Keynote Speech and Awards

POSTER SESSION:
The second annual IPHAM Population Health Forum will include a poster session. Accepted posters will highlight work supported by Northwestern with a focus on population and public health.

ABSTRACT SUBMISSION DEADLINE: FRIDAY, NOVEMBER 15, 2019, 11:59 P.M.

Find more information: https://www.feinberg.northwestern.edu/sites/ipham/events/population-health-forum.html#abstracts

Dec

Basic Research Seminar: Biology and Vulnerabilities of Circulating Tumor Cells

Chicago - 2:00 PM - 3:00 PM

The Basic Research Seminar Series of the Robert H. Lurie Comprehensive Cancer of Northwestern University and the Department of Pharmacology present:

Biology and Vulnerabilities of Circulating Tumor Cells

Nicola Aceto, Ph.D.
Swiss National Science Foundation Assistant Professor of Oncology
Faculty of Medicine, Department of BioMedicine
University of Basel

Host: Huiping Liu, MD, PhD

Light refreshments provided.

The Basic Research Seminar series presents prominent basic science speakers weekly to inspire and promote ongoing cancer research at Northwestern University.

Dec

Department of Microbiology-Immunology: Joseph Sun, PhD

Chicago - 12:00 PM - 1:00 PM

Title: Epigenetic Control of Innate and Adaptive Lymphocyte Responses

Speaker : Joseph Sun, PhD

Host: Chyung-Ru Wang, PhD

Topic:

Clonal expansion and immunological memory are hallmark features of the mammalian adaptive immune response and essential for prolonged host control of pathogens. Recent work demonstrated that natural killer (NK) cells of the innate immune system also exhibit these adaptive traits during infection. Here we demonstrate that differentiating and memory NK cells possess distinct chromatin accessibility states, and that their epigenetic profiles reveal a poised regulatory program at the memory stage. Furthermore, we elucidate how individual STAT transcription factors differentially control epigenetic and transcriptional states early during infection. Finally, concurrent chromatin profiling of the canonical CD8+ T cell response against the same infection demonstrated parallel and distinct epigenetic signatures defining NK cells and CD8+ T cells. Overall, our study reveals the dynamic nature of epigenetic modifications during the generation of innate and adaptive lymphocyte memory.

Dec

Basic Research Seminar: Curing Cancer with Differentiation Therapy

Chicago - 11:30 AM - 12:30 PM

The Basic Research Seminar Series of the Robert H. Lurie Comprehensive Cancer of Northwestern University presents:

Curing Cancer with Differentiation Therapy

John D Crispino, PhD
Robert I. Lurie, MD, and Lora S. Lurie Professor
Professor of Medicine (Hematology and Oncology) and Biochemistry and Molecular Genetics
Northwestern University Feinberg School of Medicine

Light lunch provided.

The Basic Research Seminar series presents prominent basic science speakers weekly to inspire and promote ongoing cancer research at Northwestern University.

Dec

Department of Microbiology-Immunology: Jan Carette, PhD

Chicago - 12:00 PM - 1:00 PM

Title: Genetic Dissection of Viral Pathogenesis and Host Defense

Speaker: Jan Carette, PhD

Host: Gregory A. Smith PhD

Topic:

Emerging and re-emerging viruses pose a constant threat to human health. Through advanced genetic screens we have identified proteins with critical roles in the replication of medically important viruses from diverse families including Ebola virus, rhinovirus, enterovirus, dengue virus, and hepatitis C virus. In addition, we have discovered a key cellular receptor for the AAV gene therapy vector. We are studying the molecular details on how the viruses have hijacked these host components to facilitate their pathogenesis and are characterizing the roles they play in human biology and infectious disease.

Dec

"Induced Pluripotent Stem Cells" Didactic Lecture

Chicago - 4:00 PM - 5:00 PM

Presented by:

Paul W Burridge, PhD

Assistant Professor of Pharmacology

Northwestern University

Feinberg Cardiovascular and Renal Research Institute

Dec

Dissecting the Neural Circuits Driving Pain-Induced Negative Affect - Jose Moron-Concepcion, PhD

Chicago - 10:30 AM - 11:30 AM

Jose Moron-Concepcion, PhD
Professor of Anesthesiology, Psychiatry and Neuroscience
Washington University Pain Center
Washington University School of Medicine

Remote Meeting Access
Join us remotely via Panopto.

Quality of life for patients suffering from chronic pain is impacted by co-morbidities such as prolonged negative affective states. These include decreased reward valance and diminished motivation to perform goal-directed behaviors. Current pharmacological treatments focus mainly on the nociceptive component of pain, leaving severe emotional disturbances understudied and poorly treated. Twenty five percent of patients experiencing pain misuse drugs of abuse, a maladaptive behavior that can lead to involuntary overdose and/or addiction. As the opioid epidemic in the US continues to worsen, it is critical that we determine the factors and neural circuits contributing to this severe public health issue. The negative consequences of persistent pain are likely mediated by dynamic adaptations in the central nervous system; however, the mechanisms responsible for the development of pain-induced negative affective states are not well understood. Prior work has revealed that the dynorphin-kappa opioid receptor (KOR) system, in discrete brain regions, decreases the reinforcing properties of rewards and induces dysphoria and aversive behaviors. Data presented here demonstrates that the dynorphin-KOR system in the mesolimbic pathway represents an important target for therapeutical approaches in the treatment of pain-induced negative affect.

Jose Moron-Concepcion, PhD, is a full Professor of Anesthesiology, Neuroscience and Psychiatry. His primary appointment is in the Washington University Pain Center in the basic research section. After completing his PhD in Biochemistry at the University of Barcelona (Spain), he was awarded a fellowship to join the intramural program at NIDA to work in the laboratory of Dr. Toni Shippenberg, a pioneer in the field of opioid pharmacology. Then, Dr. Moron-Concepcion continued his postdoctoral training in the laboratory of Dr. Lakshmi Devi at Mount Sinai, where he continued his studies on the mechanisms of opioid dependence. After completing his training, Dr. Moron-Concepcion moved to Columbia University in New York, where he was on the faculty of the Department of Anesthesiology for 6 years. He finally joined the faculty of Washington University on October 1, 2015. Research in his laboratory is focused in understanding the mechanisms underlying opioid addiction and the intersection with pain. In addition, his lab is interested in elucidating mechanisms underlying pain in the central nervous system and in the periphery.

Jan

"Introduction to Speckle Tracking Echocardiography" Didactic Lecture

Chicago - 4:00 PM - 5:00 PM

Presented By:

Lauren Nelson, MS, RDCS, FASE
Technical Director, Northwestern University Echocardiography Core Laboratory
Technical Director, T1 Center for Cardiovascular Developmental Therapeutics
Department of Medicine-Cardiology
Northwestern University

Feinberg Cardiovascular & Renal Research Institute

Feb

TEAM/SBDRC Seminar: Development of a B-Cell-Based Vaccine to Treat Glioblastoma

Chicago - 12:00 PM - 1:00 PM

The Robert H. Lurie Comprehensive Cancer Center of Northwestern University's TEAM Program and Northwestern's Skin Biology and Diseases Resource-Based Center present:

Development of a B-Cell-Based Vaccine to Treat Glioblastoma

Catalina Lee Chang, PhD
Research Assistant Professor of Neurological Surgery
Northwestern University Feinberg School of Medicine

Refreshments will be provided.

Mar

"Mechanisms Underlying Atrial Fibrillation" Didactic Lecture

Chicago - 4:00 PM - 5:00 PM

Presented by:

Rishi Arora, MD

Professor of Cardiology

Northwestern University

Feinberg Cardiovascular and Renal Research Institute

Apr

"Phagocytes for Resolution, Repair, & Regeneration of CVD" Didactic Lecture

Chicago - 4:00 PM - 5:00 PM

Presented By:

Edward Benjamin Thorp, PhD
Associate Professor of Pathology and Pediatrics
Northwestern University

Feinberg Cardiovascular & Renal Research Institute