Northwestern University Feinberg School of Medicine
Robert H. Lurie Comprehensive Cancer Center of Northwestern University
Lou and Jean Malnati Brain Tumor Institute


We're proud to be part of the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, one of just six cancer centers in the country to have received the National Cancer Institute's highly competitive Specialized Program of Research Excellence (SPORE) grant to support brain tumor research. This five-year, $11.5 million grant, which we received in 2018, is fueling research focused on developing new treatments for glioblastomas.

The Institute's objective is to advance brain tumor research through a multidisciplinary, team-based approach. By bringing together a team of outstanding clinicians and scientists, each with their own specialized background and expertise, we are advancing cutting-edge therapeutic approaches at an accelerated pace relative to that which is possible through individual effort. The Malnati Brain Tumor Institute is a world-class institute because our whole effort is greater than the sum of its parts.”

C. David James, PhD, Scientific Director of Research

Stem Cells as Producers of Oncolytic Virus

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Increasing Patient Immune Response Against Tumor

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Nanoparticles for Delivery of Inhibitory Nucleic Acids

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Inhibiting Autophagy to Increase the Anti-Tumor Activity of Conventional Therapy

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Activity and Resources

Our Investigators

Our investigators approach brain and spinal tumors from a variety of perspectives and fields of study. Learn about their focus at the Malnati Brain Tumor Institute.

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Skull Base Lab

The Skull Base Lab emphasizes a comprehensive and translational approach using real surgical techniques that better equip trainees with the skills they need in the operating room.

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Nervous System Tumor Bank

The Northwestern University Nervous System Tumor Bank (NSTB) provides Northwestern researchers with high-quality patient-derived biospecimens (tissues, cells, blood, and cerebrospinal fluid) and data.
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Lurie Cancer Center

Shared Resources

Scientists should visit the Shared Resources and Research sections of the Robert H. Lurie Comprehensive Cancer Center of Northwestern University website. Find out about the services, tools, and facilities available.

Scientists within our institutes have leadership positions in the cancer center core facilities and services:

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