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Northwestern University Feinberg School of Medicine
Institute for Artificial Intelligence in Medicine

Publications

Browse the list below to see the latest scientific publications stemming from our institute faculty’s work. To view publications of specific AI faculty, please visit Membership and select a profile link.

  1. Kim M, Wang X, Li Y, Lin Z, Collins CP, Liu Y, Ahn Y, Tsal HM, Song JW, Duan C  et al.  Personalized composite scaffolds for accelerated cell- and growth factor-free craniofacial bone regeneration.  Bioact Mater  2024 Nov;41:427-439. doi:10.1016/j.bioactmat.2024.07.029
  2. Shah SJ, Sharma K, Borlaug BA, Butler J, Davies M, Kitzman DW, Petrie MC, Verma S, Patel S, Chinnakondepalli KM  et al.  Semaglutide and diuretic use in obesity-related heart failure with preserved ejection fraction: a pooled analysis of the STEP-HFpEF and STEP-HFpEF-DM trials.  Eur Heart J  2024 Sep 14;45(35):3254-3269. doi:10.1093/eurheartj/ehae322
  3. Chaudhury AS, Ige M, Marwah S, Zhou X, Andrews CA, Kanwar K, Evans CT, Kho AN, Stein JD, Bryar PJ  et al.  Race, Social Determinants of Health, and the Quality of Diabetic Eye Care.  JAMA Ophthalmol  2024 Sep 12;. pii:e243528
  4. Peterson TE, Lima JAC, Shah SJ, Bluemke DA, Bertoni AG, Liu Y, Ngo D, Varadarajan V, Mychaleckyj JC, Johnson CW  et al.  Proteomics of left ventricular structure in the Multi-Ethnic Study of Atherosclerosis.  ESC Heart Fail  2024 Sep 12;. doi:10.1002/ehf2.15073
  5. Kosiborod MN, Deanfield J, Pratley R, Borlaug BA, Butler J, Davies MJ, Emerson SS, Kahn SE, Kitzman DW, Lingvay I  et al.  Semaglutide versus placebo in patients with heart failure and mildly reduced or preserved ejection fraction: a pooled analysis of the SELECT, FLOW, STEP-HFpEF, and STEP-HFpEF DM randomised trials.  Lancet  2024 Sep 07;404(10456):949-961. doi:10.1016/S0140-6736(24)01643-X
  6. Culler KL, Sinha A, Filipp M, Giro P, Allen NB, Taylor KD, Guo X, Thorp E, Freed BH, Greenland P  et al.  Metabolomic profiling identifies novel metabolites associated with cardiac dysfunction.  Sci Rep  2024 Sep 05;14(1):20694. pii:20694
  7. Solomon SD, McMurray JJV, Vaduganathan M, Claggett B, Jhund PS, Desai AS, Henderson AD, Lam CSP, Pitt B, Senni M  et al.  Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction.  N Engl J Med  2024 Sep 01;. doi:10.1056/NEJMoa2407107
  8. Vaduganathan M, Filippatos G, Claggett BL, Desai AS, Jhund PS, Henderson A, Brinker M, Kolkhof P, Schloemer P, Lay-Flurrie J  et al.  Finerenone in Heart Failure and Chronic Kidney Disease with Type 2 Diabetes: the FINE-HEART pooled analysis of cardiovascular, kidney, and mortality outcomes.  Nat Med  2024 Sep 01;. doi:10.1038/s41591-024-03264-4
  9. deFilippi CR, Shah P, Shah SJ, Alemayehu W, Lam CSP, Butler J, Roessig L, O'Connor CM, Westerhout CM, Armstrong PW  et al.  Proteomics Identify Clinical Phenotypes and Predict Functional Outcomes in Heart Failure With Preserved Ejection Fraction: Insights From VITALITY-HFpEF.  Circ Heart Fail  2024 Sep;17(9):e011792. doi:10.1161/CIRCHEARTFAILURE.124.011792
  10. Luo Y, Meng X, Zhou G, Zhou J, Luo YJ, Ai H, Zelano C, Chen F, Xu P  Oscillatory mechanisms of intrinsic human brain networks.  Neuroimage  2024 Sep;298:120773. doi:10.1016/j.neuroimage.2024.120773
  11. Ashworth RC, Malone JR, Franklin D, Sorce LR, Clayman ML, Frader J, White DB, Michelson KN  Associations of Patient and Parent Characteristics With Parental Decision Regret in the PICU: A Secondary Analysis of the 2015-2017 Navigate Randomized Comparative Trial.  Pediatr Crit Care Med  2024 Sep 01;25(9):795-803. doi:10.1097/PCC.0000000000003534
  12. Ahmad FS, Hu TL, Adler ED, Petito LC, Wehbe RM, Wilcox JE, Mutharasan RK, Nardone B, Tadel M, Greenberg B  et al.  Performance of risk models to predict mortality risk for patients with heart failure: evaluation in an integrated health system.  Clin Res Cardiol  2024 Sep;113(9):1343-1354. doi:10.1007/s00392-024-02433-2
  13. Dalal PJ, Giro P, Rasmussen-Torvik LJ, Yancy CW, Shah SJ, Reiner AP, Haring B, Martin LW, Wells GL, Manson JE  et al.  Heart Failure Risk Among African-American Women With an ICAM1 Missense Variant.  JACC Heart Fail  2024 Sep;12(9):1614-1624. doi:10.1016/j.jchf.2024.02.002
  14. Munsell EGS, Bui Q, Kaufman KJ, Tomazin SE, Regan BA, Lenze EJ, Lee JM, Mohr DC, Fong MWM, Metts CL  et al.  Intraindividual variability in post-stroke cognition and its relationship with activities of daily living and social functioning: an ecological momentary assessment approach.  Top Stroke Rehabil  2024 Sep;31(6):564-575. doi:10.1080/10749357.2024.2307203
  15. Jhund PS, Talebi A, Henderson AD, Claggett BL, Vaduganathan M, Desai AS, Lam CSP, Pitt B, Senni M, Shah SJ  et al.  Mineralocorticoid receptor antagonists in heart failure: an individual patient level meta-analysis.  Lancet  2024 Aug 30;. pii:S0140-6736(24)01733-1
  16. Perry AS, Amancherla K, Huang X, Lance ML, Farber-Eger E, Gajjar P, Amrute J, Stolze L, Zhao S, Sheng Q  et al.  Clinical-transcriptional prioritization of the circulating proteome in human heart failure.  Cell Rep Med  2024 Aug 30;:101704. doi:10.1016/j.xcrm.2024.101704
  17. Docherty KF, Lopez RB, Folkvaljon F, De Boer RA, Cowie MR, Hammarstedt A, Kitzman DW, Kosiborod MN, Langkilde AM, Reicher B  et al.  The Effect of Dapagliflozin on Accelerometer-Based Measures of Physical Activity in Patients with Heart Failure: An Analysis of the DETERMINE Trials.  Circ Heart Fail  2024 Aug 30;. doi:10.1161/CIRCHEARTFAILURE.124.012349
  18. Solomon SD, Ostrominski JW, Wang X, Shah SJ, Borlaug BA, Butler J, Davies MJ, Kitzman DW, Verma S, Abildstrøm SZ  et al.  Effect of Semaglutide on Cardiac Structure and Function in Patients With Obesity-Related Heart Failure.  J Am Coll Cardiol  2024 Aug 29;. pii:S0735-1097(24)08192-0
  19. Verma S, Butler J, Borlaug BA, Davies MJ, Kitzman DW, Petrie MC, Shah SJ, Jensen TJ, Rasmussen S, Rönnbäck C  et al.  Atrial Fibrillation and Semaglutide Effects in Obesity-Related Heart Failure With Preserved Ejection Fraction: STEP-HFpEF Program.  J Am Coll Cardiol  2024 Aug 29;. pii:S0735-1097(24)08195-6
  20. Verma S, Petrie MC, Borlaug BA, Butler J, Davies MJ, Kitzman DW, Shah SJ, Rönnbäck C, Abildstrøm SZ, Liisberg K  et al.  Inflammation in Obesity-Related HFpEF: The STEP-HFpEF Program.  J Am Coll Cardiol  2024 Aug 28;. pii:S0735-1097(24)08234-2
  21. Wu Y, Iorga M, Badhe S, Zhang J, Cantrell DR, Tanhehco EJ, Szrama N, Naidech AM, Drakopoulos M, Hasan ST  et al.  Precise Image-level Localization of Intracranial Hemorrhage on Head CT Scans with Deep Learning Models Trained on Study-level Labels.  Radiol Artif Intell  2024 Aug 28;:e230296. doi:10.1148/ryai.230296
  22. Verma S, Butler J, Borlaug BA, Davies M, Kitzman DW, Shah SJ, Petrie MC, Barros E, Rönnbäck C, Vestergaard LS  et al.  Efficacy of Semaglutide by Sex in Obesity-Related Heart Failure With Preserved Ejection Fraction: STEP-HFpEF Trials.  J Am Coll Cardiol  2024 Aug 27;84(9):773-785. doi:10.1016/j.jacc.2024.06.001
  23. Sorimachi H, Obokata M, Omote K, Reddy YNV, Burkhoff D, Shah SJ, Borlaug BA  Racial Differences of Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction.  J Card Fail  2024 Aug 23;. pii:S1071-9164(24)00356-7
  24. Yang M, Kondo T, Anand IS, de Boer RA, Campbell RT, Køber L, Lam CSP, Maggioni AP, Martinez FA, O'Meara E  et al.  Clinical characteristics and outcomes of patients aged 80 years and over with heart failure: Need for better treatment.  Eur J Heart Fail  2024 Aug 21;. doi:10.1002/ejhf.3417
  25. Amagai S, Vonesh E, Adams J, Luo Y  Closing the gap: addressing telehealth disparities across specialties in the sustained pandemic era.  NPJ Digit Med  2024 Aug 21;7(1):217. pii:217
  26. Xiang G, He X, Giardine BM, Isaac KJ, Taylor DJ, McCoy RC, Jansen C, Keller CA, Wixom AQ, Cockburn A  et al.  Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes.  Genome Res  2024 Aug 20;34(7):1089-1105. doi:10.1101/gr.277950.123
  27. Bramante CT, Beckman KB, Mehta T, Karger AB, Odde DJ, Tignanelli CJ, Buse JB, Johnson DM, Watson RHB, Daniel JJ  et al.  Favorable Antiviral Effect of Metformin on SARS-CoV-2 Viral Load in a Randomized, Placebo-Controlled Clinical Trial of COVID-19.  Clin Infect Dis  2024 Aug 16;79(2):354-363. doi:10.1093/cid/ciae159
  28. Hamo CE, DeJong C, Hartshorne-Evans N, Lund LH, Shah SJ, Solomon S, Lam CSP  Heart failure with preserved ejection fraction.  Nat Rev Dis Primers  2024 Aug 14;10(1):55. doi:10.1038/s41572-024-00540-y
  29. Kitzman DW, Voors AA, Mentz RJ, Lewis GD, Perl S, Myte R, Kaguthi G, Sjöström CD, Källgren C, Shah SJ  Verinurad Plus Allopurinol for Heart Failure With Preserved Ejection Fraction: The AMETHYST Randomized Clinical Trial.  JAMA Cardiol  2024 Aug 14;. pii:e242435
  30. Campos C, Magwire M, Butler J, Hoovler A, Sabharwal A, Shah SJ  Diagnostic and therapeutic challenges for PCPs regarding heart failure with preserved ejection fraction and obesity: results of an online internet-based survey.  BMC Prim Care  2024 Aug 08;25(1):288. pii:288
  31. Li Y, Luo Y  STdGCN: spatial transcriptomic cell-type deconvolution using graph convolutional networks.  Genome Biol  2024 Aug 05;25(1):206. pii:206
  32. Sadeghpour A, Jiang Z, Hummel YM, Frost M, Lam CSP, Shah SJ, Lund LH, Stone GW, Swaminathan M, Weissman NJ  et al.  An Automated Machine Learning-Based Quantitative Multiparametric Approach for Mitral Regurgitation Severity Grading.  JACC Cardiovasc Imaging  2024 Aug 02;. pii:S1936-878X(24)00247-X
  33. Gustafsson F, Petrie MC, Komtebedde J, Swarup V, Winkler S, Hasenfuß G, Borlaug BA, Mohan RC, Flaherty JD, Sverdlov AL  et al.  2-Year Outcomes of an Atrial Shunt Device in HFpEF/HFmrEF: Results From REDUCE LAP-HF II.  JACC Heart Fail  2024 Aug;12(8):1425-1438. doi:10.1016/j.jchf.2024.04.011
  34. Kondo T, Campbell R, Jhund PS, Anand IS, Carson PE, Lam CSP, Shah SJ, Vaduganathan M, Zannad F, Zile MR  et al.  Low Natriuretic Peptide Levels and Outcomes in Patients With Heart Failure and Preserved Ejection Fraction.  JACC Heart Fail  2024 Aug;12(8):1442-1455. doi:10.1016/j.jchf.2024.04.027
  35. Ladner DP, Manski CF, Mehrotra S  New Liver Allocation Policy and National Liver Transplant Volume.  JAMA Surg  2024 Aug 01;159(8):947-948. doi:10.1001/jamasurg.2024.1209
  36. Gao J, Giro P, Delaney JA, Rasmussen-Torvik L, Taylor KD, Thorp EB, Doyle MF, Feinstein MJ, Sitlani CM, Olson N  et al.  Immune cell profiling of the ICAM1 p.K56M heart failure with preserved ejection fraction risk variant.  ESC Heart Fail  2024 Jul 22;. doi:10.1002/ehf2.14983
  37. Shimbo D, Shah RU, Abdalla M, Agarwal R, Ahmad FS, Anaya G, Attia ZI, Bull S, Chang AR, Commodore-Mensah Y  et al.  Transforming Hypertension Diagnosis and Management in The Era of Artificial Intelligence: A 2023 National Heart, Lung, and Blood Institute (NHLBI) Workshop Report.  Hypertension  2024 Jul 16;. doi:10.1161/HYPERTENSIONAHA.124.22095
  38. Schou M, Petrie MC, Borlaug BA, Butler J, Davies MJ, Kitzman DW, Shah SJ, Verma S, Patel S, Chinnakondepalli KM  et al.  Semaglutide and NYHA Functional Class in Obesity-Related Heart Failure With Preserved Ejection Fraction: The STEP-HFpEF Program.  J Am Coll Cardiol  2024 Jul 16;84(3):247-257. doi:10.1016/j.jacc.2024.04.038
  39. Doiron JE, Xia H, Yu X, Nevins AR, LaPenna KB, Sharp TE, Goodchild TT, Allerton TD, Elgazzaz M, Lazartigues E  et al.  Adjunctive therapy with an oral H2S donor provides additional therapeutic benefit beyond SGLT2 inhibition in cardiometabolic heart failure with preserved ejection fraction.  Br J Pharmacol  2024 Jul 09;. doi:10.1111/bph.16493
  40. Simon GE, Moise N, Mohr DC  Management of Depression in Adults: A Review.  JAMA  2024 Jul 09;332(2):141-152. doi:10.1001/jama.2024.5756
  41. Zhang D, Stein R, Lu Y, Zhou T, Lei Y, Li L, Chen J, Arnold J, Becich MJ, Chrischilles EA  et al.  Pediatric Gastrointestinal Outcomes During the Post-Acute Phase of COVID-19: Findings from RECOVER Initiative from 29 Hospitals in the US.  medRxiv  2024 Jul 09;. pii:2024.05.21.24307699
  42. Maimone C, Dolan BM, Green MM, Sanguino SM, O'Brien CL  Using Natural Language Processing to Visualize Narrative Feedback in a Medical Student Performance Dashboard.  Acad Med  2024 Jul 03;. doi:10.1097/ACM.0000000000005800
  43. Wittbrodt M, Klug M, Etemadi M, Yang A, Pandolfino JE, Keswani RN  Assessment of colonoscopy skill using machine learning to measure quality: Proof-of-concept and initial validation.  Endosc Int Open  2024 Jul;12(7):E849-E853. doi:10.1055/a-2333-8138
  44. Petrie MC, Borlaug BA, Butler J, Davies MJ, Kitzman DW, Shah SJ, Verma S, Jensen TJ, Einfeldt MN, Liisberg K  et al.  Semaglutide and NT-proBNP in Obesity-Related HFpEF: Insights From the STEP-HFpEF Program.  J Am Coll Cardiol  2024 Jul 02;84(1):27-40. doi:10.1016/j.jacc.2024.04.022
  45. Bermea KC, Lovell JP, Hays AG, Goerlich E, Vungarala S, Jani V, Shah SJ, Sharma K, Adamo L  A Machine Learning-Derived Score to Effectively Identify Heart Failure With Preserved Ejection Fraction.  JACC Adv  2024 Jul;3(7):101040. pii:101040
  46. Abdollahi A, Kato Y, Bakhshi H, Varadarajan V, Chehab O, Zeitoun R, Ostovaneh MR, Wu CO, Bertoni AG, Shah SJ  et al.  Differential Stroke Volume between Left and Right Ventricles as a Predictor of Clinical Outcomes: The MESA Study.  Radiology  2024 Jul;312(1):e232973. pii:e232973
  47. Luo Y, Mao C, Sanchez-Pinto LN, Ahmad FS, Naidech A, Rasmussen L, Pacheco JA, Schneider D, Mithal LB, Dresden S  et al.  Northwestern University resource and education development initiatives to advance collaborative artificial intelligence across the learning health system.  Learn Health Syst  2024 Jul;8(3):e10417. pii:e10417
  48. Patel RB, Shah SJ  Left Atrial Myopathy in Heart Failure With Preserved Ejection: Don't Raise the Roof!  Circ Cardiovasc Imaging  2024 Jul;17(7):e017137. doi:10.1161/CIRCIMAGING.124.017137
  49. Lassen MCH, Ostrominski JW, Inzucchi SE, Claggett BL, Kulac I, Jhund P, de Boer RA, Hernandez AF, Kosiborod MN, Lam CSP  et al.  Effect of dapagliflozin in patients with diabetes and heart failure with mildly reduced or preserved ejection fraction according to background glucose-lowering therapy: A pre-specified analysis of the DELIVER trial.  Eur J Heart Fail  2024 Jul;26(7):1539-1548. doi:10.1002/ejhf.3269
  50. Jani VP, Strom JB, Gami A, Beussink-Nelson L, Patel R, Michos ED, Shah SJ, Freed BH, Mukherjee M  Optimal Method for Assessing Right Ventricular to Pulmonary Arterial Coupling in Older Healthy Adults: The Multi-Ethnic Study of Atherosclerosis.  Am J Cardiol  2024 Jul 01;222:11-19. doi:10.1016/j.amjcard.2024.03.043