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Northwestern University Feinberg School of Medicine
Institute for Artificial Intelligence in Medicine

Publications

Browse the list below to see the latest scientific publications stemming from our institute faculty’s work. To view publications of specific AI faculty, please visit Membership and select a profile link.

  1. Kruzan KP, Ammerman B, Lengel GJ, Griffith JW, Lucas K, Nguyen T, Rushton K, Washburn JJ, Mohr DC  Development and initial test of an online self-assessment of nonsuicidal self-injury severity.  J Affect Disord  2025 Oct 15;387:119506. doi:10.1016/j.jad.2025.119506
  2. Prasad D, Khandeshi A, Sartin S, Jain R, Dahdaleh N, Lesniak M, Luo Y, Ahuja C  Will AI become our Co-PI?  NPJ Digit Med  2025 Jul 14;8(1):440. doi:10.1038/s41746-025-01859-w
  3. Fass OZ, Kristinsdottir K, Kaklamanos E, Soni P, Hudson K, Etemadi M, Pandolfino JE, Carlson DA  Improved Performance of an Updated Artificial Intelligence Model for Interpretation of Functional Lumen Imaging Probe Panometry Studies.  Neurogastroenterol Motil  2025 Jul 13;:e70120. doi:10.1111/nmo.70120
  4. Wang X, Li Y, Lin Z, Pla I, Gajjela R, Mattamana BB, Joshi M, Liu Y, Wang H, Zun AB  et al.  Microtopography-induced changes in cell nucleus morphology enhance bone regeneration by modulating the cellular secretome.  Nat Commun  2025 Jul 11;16(1):6444. pii:6444
  5. Rosenthal EA, Wei WQ, Luo Y, Namjou-Khales B, Schaid DJ, Esplin ED, Lape M, Kottyan L, Pacheco JA, Weng C  et al.  Phenome-wide association study identifies multiple traits associated with a polygenic risk score for colorectal cancer.  Hum Genomics  2025 Jul 09;19(1):77. pii:77
  6. Luo Z, Xia M, Shi W, Zhao C, Wang J, Xin D, Dong X, Xiong Y, Zhang F, Berry K  et al.  Retraction Note: Human fetal cerebellar cell atlas informs medulloblastoma origin and oncogenesis.  Nature  2025 Jul 09;. doi:10.1038/s41586-025-09015-w
  7. Mithal LB, Becker ME, Ling-Hu T, Goo YA, Otero S, Kremer A, Pandey S, Lancki N, Li Y, Luo Y  et al.  Cord blood proteomics identifies biomarkers of early-onset neonatal sepsis.  JCI Insight  2025 Jul 08;10(13). pii:e193826
  8. Yaku H, Burkhoff D, Borlaug BA, Lala A, Butler J, Rich S, Shah SJ  Oral Levosimendan for the Treatment of Pulmonary Hypertension due to Heart Failure with Preserved Ejection Fraction: Rationale and Design of the LEVEL Trial: Rationale and Design of LEVEL.  J Card Fail  2025 Jul 07;. pii:S1071-9164(25)00293-3
  9. Hourmozdi J, Easton N, Benigeri S, Thomas JD, Narang A, Ouyang D, Duffy G, Upton R, Hawkes W, Akerman A  et al.  Evaluating the Performance and Potential Bias of Predictive Models for Detection of Transthyretin Cardiac Amyloidosis.  JACC Adv  2025 Jul 04;4(8):101901. doi:10.1016/j.jacadv.2025.101901
  10. Yaku H, Eicher JC, Bergmann MW, Kister T, Pörner TC, Borlaug BA, Mohan RC, Price M, Komtebedde J, Shah SJ  Management of Flow Reversal in Patients With Atrial Shunts Implanted to Reduce Left Atrial Pressure.  JACC Case Rep  2025 Jul 02;30(17):103893. doi:10.1016/j.jaccas.2025.103893
  11. Naved BA, Ravishankar S, Colbert GE, Johnston A, Slott QM, Luo Y  LLM enabled classification of patient self-reported symptoms and needs in health systems across the USA.  NPJ Digit Med  2025 Jul 01;8(1):390. pii:390
  12. Pabon MA, Vardeny O, Vaduganathan M, Desai AS, Claggett BL, Kulac IJ, Jhund PS, Lam CSP, Senni M, Shah SJ  et al.  Finerenone in Heart Failure With Improved Ejection Fraction: The FINEARTS-HF Randomized Clinical Trial.  JAMA Cardiol  2025 Jul 01;10(7):740-745. doi:10.1001/jamacardio.2025.1101
  13. Barrett MA, Allen A, Vuong VT, Zhu D, Rainey AJ, McConnell WM, Kho AN, Salisbury A, French DD  Impact of an Artificial Intelligence and Machine Learning Enhanced Electronic Health Record System on Quality Measures in Nursing Homes: A Difference-in-Differences Analysis.  J Am Med Dir Assoc  2025 Jul;26(7):105680. doi:10.1016/j.jamda.2025.105680
  14. Dennis S, Tsukioki T, Kocherginsky M, Qi AK, DeHorn S, Gurley M, Wrubel E, Luo Y, Khan SA  ASO Visual Abstract: Neoadjuvant Chemotherapy Response and Genetic Susceptibility in Recently Parous Women with Breast Cancer: A Retrospective Analysis.  Ann Surg Oncol  2025 Jul;32(7):4916-4917. doi:10.1245/s10434-025-17370-1
  15. Dennis S, Tsukioki T, Kocherginsky M, Qi AK, DeHorn S, Gurley M, Wrubel E, Luo Y, Khan SA  Neoadjuvant Chemotherapy Response and Genetic Susceptibility in Recently Parous Women with Breast Cancer: A Retrospective Analysis.  Ann Surg Oncol  2025 Jul;32(7):4855-4864. doi:10.1245/s10434-025-17204-0
  16. Matsumoto S, Henderson AD, Jhund PS, Bauersachs J, Chioncel O, Claggett BL, Comin-Colet J, Desai AS, Filippatos G, Lam CSP  et al.  Finerenone and Atrial Fibrillation in Heart Failure: A Secondary Analysis of the FINEARTS-HF Randomized Clinical Trial.  JAMA Cardiol  2025 Jul 01;10(7):696-707. doi:10.1001/jamacardio.2025.0848
  17. Li M, Fass OZ, Carlson DA, Pitisuttithum P, Goudie E, Kristinsdottir K, Kaklamanos E, Etemadi M, Keswani RN, Ellison A  et al.  Endoscopic Prediction of Achalasia: Putting the CART Before the CARS.  Neurogastroenterol Motil  2025 Jul;37(7):e70024. pii:e70024
  18. Hosseini M, Holcombe AO, Kovacs M, Zwart H, Katz DS, Holmes K  Group authorship, an excellent opportunity laced with ethical, legal and technical challenges.  Account Res  2025 Jul;32(5):762-784. doi:10.1080/08989621.2024.2322557
  19. Ding Y, He B, Bogush D, Schramm J, Singh C, Dovat K, Randazzo J, Tukaramrao D, Hengst J, Annageldiyev C  et al.  Critical roles of IKAROS and HDAC1 in regulation of heterochromatin and tumor suppression in T-cell acute lymphoblastic leukemia.  Leukemia  2025 Jun 24;. doi:10.1038/s41375-025-02651-1
  20. Herrold AA, Aaronson AL, Bhaumik D, Durazzo T, Livengood SL, Ramic A, Riordan P, Jordan N, Parrish T, Mallinson T  et al.  A Customized Neural Transcranial Magnetic Stimulation Target for Functional Disability Among Veterans With Co-Occurring Alcohol Use Disorder and Mild Traumatic Brain Injury: Protocol for a Pilot Randomized Controlled Trial.  JMIR Res Protoc  2025 Jun 23;14:e64909. pii:e64909
  21. Klein L, Fudim M, Etemadi M, Gordon R, Tibrewala A, Hernandez-Montfort J, McCann P, Zier L, Shah K, Rollins A  et al.  Noninvasive Pulmonary Capillary Wedge Pressure Estimation in Heart Failure Patients With the Use of Wearable Sensing and AI.  JACC Heart Fail  2025 Jun 20;13(8):102513. doi:10.1016/j.jchf.2025.102513
  22. Butt JH, Jhund PS, Henderson AD, Claggett BL, Chiang CE, Linssen GCM, Saldarriaga CI, Saraiva JFK, Sato N, Schou M  et al.  Finerenone According to Frailty in Heart Failure: A Prespecified Analysis of the FINEARTS-HF Randomized Clinical Trial.  JAMA Cardiol  2025 Jun 18;. pii:e251775
  23. Bisen JB, Sikora H, Aneja A, Shah SJ, Mirza RG  Retinal Imaging as a Window into Cardiovascular Health: Towards Harnessing Retinal Analytics for Precision Cardiovascular Medicine.  J Cardiovasc Dev Dis  2025 Jun 17;12(6). pii:230
  24. Li Y, Ding Y, Dennis S, Hutch MR, Zhou J, Zhou Y, Li Y, Pillai M, Ghotbaldini S, Garcia MA  et al.  SOAR elucidates biological insights and empowers drug discovery through spatial transcriptomics.  Sci Adv  2025 Jun 13;11(24):eadt7450. doi:10.1126/sciadv.adt7450
  25. Ostrominski JW, Filippatos G, Claggett BL, Miao ZM, Desai AS, Jhund PS, D Henderson A, Scheerer MF, Rohwedder K, Amarante F  et al.  Efficacy and Safety of Finerenone in Heart Failure With Preserved Ejection Fraction: A FINE-HEART Analysis.  JACC Heart Fail  2025 Jun 11;13(8):102497. doi:10.1016/j.jchf.2025.03.041
  26. Dennis SR, Tsukioki T, Cottone G, Zhou W, Ganz PA, Sehl ME, Luo Y, Khan SA, Clare S  DNA methylation patterns in breast cancer, paired benign tissue from ipsilateral and contralateral breast, and healthy controls.  Breast Cancer Res  2025 Jun 11;27(1):103. pii:103
  27. Ozyoruk KB, Harmon SA, Yilmaz EC, Gelikman DG, Bagci U, Simon BD, Merino MJ, Lis R, Gurram S, Wood BJ  et al.  Impact of AI-Generated ADC Maps on Computer-Aided Diagnosis of Prostate Cancer: A Feasibility Study.  Acad Radiol  2025 Jun 04;. pii:S1076-6332(25)00518-5
  28. Huang J, Wittbrodt MT, Teague CN, Karl E, Galal G, Thompson M, Chapa A, Chiu ML, Herynk B, Linchangco R  et al.  Efficiency and Quality of Generative AI-Assisted Radiograph Reporting.  JAMA Netw Open  2025 Jun 02;8(6):e2513921. pii:e2513921
  29. Rambarat P, DeVore AD, Bhatt AS, Allen LA, McIlvennan CK, Cotter G, Mukhopadhyay A, Ahmad T, Ahmad FS, Psotka MA  Failure to Launch: Insights From Randomized Trials on Implementation Strategies for Guideline-Directed Therapies for Heart Failure.  JACC Heart Fail  2025 Jun;13(6):887-900. doi:10.1016/j.jchf.2025.02.023
  30. Sehgal S, Starren J, Cattin K, Bilaver L, Gururaj A, Togias A, Gupta RS  Common data elements for food allergy clinical trials: an overview.  Curr Opin Allergy Clin Immunol  2025 Jun 01;25(3):194-198. doi:10.1097/ACI.0000000000001075
  31. Brokamp E, Miller-Fleming T, Scalici A, Hooker G, Hamid R, Velez Edwards D, Chung WK, Luo Y, Kiryluk K, Limidi NA  et al.  Systematic method for classifying multiple congenital anomaly cases in electronic health records.  Genet Med  2025 Jun;27(6):101415. doi:10.1016/j.gim.2025.101415
  32. Sandlow S, Carbunaru S, Sun Z, Ofori B, Liu Y, Li E, Hollowell CMP, Vidal P, Perry KT, Patel HD  et al.  Negative Predictive Value of a Prostate MRI in Black Men: Implications for Biopsy Decision-Making.  J Urol  2025 Jun;213(6):713-721. doi:10.1097/JU.0000000000004498
  33. Armoundas AA, Ahmad FS, Attia ZI, Doudesis D, Khera R, Kyriakoulis KG, Stergiou GS, Tang WHW  Controversy in Hypertension: Pro-Side of the Argument Using Artificial Intelligence for Hypertension Diagnosis and Management.  Hypertension  2025 Jun;82(6):929-944. doi:10.1161/HYPERTENSIONAHA.124.22349
  34. Pandey A, Lewis GD, Borlaug BA, Shah SJ, Sauer AJ, Litwin S, Sharma K, Jorkasky DK, Tarka EA, Khan SM  et al.  Novel Controlled Metabolic Accelerator for Obesity-Related HFpEF: The HuMAIN-HFpEF Randomized Clinical Trial.  JAMA Cardiol  2025 Jun 01;10(6):609-616. doi:10.1001/jamacardio.2025.0103
  35. Tavolinejad H, Boczar KE, Spronck B, Maynard H, Bertoni AG, Shah SJ, Chirinos JA  Determinants of Cardio-Ankle Vascular Index and Heart-Thigh β Index in the MESA.  Hypertension  2025 Jun;82(6):1081-1094. doi:10.1161/HYPERTENSIONAHA.124.23970
  36. McDowell K, Docherty KF, Campbell RT, Henderson AD, Jhund PS, Claggett BL, Desai AS, Lay-Flurrie J, Hofmeister L, Scalise A  et al.  Finerenone for Heart Failure and Risk Estimated by the PREDICT-HFpEF Model: A Secondary Analysis of FINEARTS-HF.  JAMA Cardiol  2025 Jun 01;10(6):535-544. doi:10.1001/jamacardio.2025.0025
  37. Ambrosy AP, Sauer AJ, Patel S, Windsor SL, Borlaug BA, Husain M, Inzucchi SE, Kitzman DW, McGuire DK, Shah SJ  et al.  Baseline kidney function and the effects of dapagliflozin on health status in heart failure in DEFINE-HF and PRESERVED-HF.  ESC Heart Fail  2025 Jun;12(3):1676-1681. doi:10.1002/ehf2.15184
  38. Michelson KN, Fishman AC, Feinberg EC, Ross S, Wald HS, Auerbach C, Roth S  Antisemitism in American Healthcare: A Survey Study of Reported Experiences.  J Gen Intern Med  2025 Jun;40(8):1940-1943. doi:10.1007/s11606-024-09159-x
  39. Hasjim BJ, Mohammadi M, Balbale SN, Paukner M, Banea T, Shi H, Furmanchuk A, VanWagner LB, Zhao L, Duarte-Rojo A  et al.  High Hospitalization Rates and Risk Factors Among Frail Patients With Cirrhosis: A 10-year Population-based Cohort Study.  Clin Gastroenterol Hepatol  2025 Jun;23(7):1152-1163. doi:10.1016/j.cgh.2024.08.044
  40. Goldstein JA, Nateghi R, Cooper LAD  Machine Learning Assessment of Gestational Age in Accelerated Maturation, Delayed Maturation, Villous Edema, Chorangiosis, and Intrauterine Fetal Demise.  Arch Pathol Lab Med  2025 Jun 01;149(6):503-510. doi:10.5858/arpa.2024-0274-OA
  41. Agha E, Sutter C, Ojewuyi I, Abramsohn EM, Andriano M, Bell C, Calix AL, Cherry JL, Downing K, Flower T  et al.  The Grief Navigation Trial: A multi-site pragmatic comparative effectiveness trial of two interventions to support parents after their child's unexpected or traumatic death.  Contemp Clin Trials  2025 May 26;155:107962. doi:10.1016/j.cct.2025.107962
  42. Wang M, Liu Z, Ren S, Zhu J, Morisawa N, Chua GL, Zhang X, Wong YK, Su L, Wong MX  et al.  BCAA catabolism targeted therapy for heart failure with preserved ejection fraction.  Theranostics  2025;15(13):6257-6273. doi:10.7150/thno.105894
  43. Lefer DJ, Sharp TE, Scarborough AL, Haydel AG, Shah SJ, Li Z, Goodchild TT  Renal denervation improves cardiac function and exercise duration in a miniswine model of heart failure with preserved ejection fraction.  Eur J Heart Fail  2025 May 22;. doi:10.1002/ejhf.3700
  44. Filipp M, Ge ZD, DeBerge M, Lantz C, Glinton K, Gao P, Smolgovsky S, Dai J, Zhao YY, Yvan-Charvet L  et al.  Myeloid Fatty Acid Metabolism Activates Neighboring Hematopoietic Stem Cells to Promote Heart Failure With Preserved Ejection Fraction.  Circulation  2025 May 20;151(20):1451-1466. doi:10.1161/CIRCULATIONAHA.124.070248
  45. Jha D, Durak G, Das A, Sanjotra J, Susladkar O, Sarkar S, Rauniyar A, Kumar Tomar N, Peng L, Li S  et al.  Ethical framework for responsible foundational models in medical imaging.  Front Med (Lausanne)  2025;12:1544501. pii:1544501
  46. Keles E, Ali SY, Wintermark P, Annaert P, Groenendaal F, Şahin S, Öncel MY, Armangil D, Koc E, Battin MR  et al.  Machine learning based clinical decision tool to predict acute kidney injury and survival in therapeutic hypothermia treated neonates.  Sci Rep  2025 May 19;15(1):17278. pii:17278
  47. Weerts J, Barandiarán Aizpurua A, Patel RB, van de Bovenkamp AA, Amin H, Sanders-van Wijk S, Mourmans SGJ, Achten A, Handoko ML, Bayés-Genís A  et al.  A simplified approach for diagnosing heart failure with preserved ejection fraction by assessing the left atrium and natriuretic peptides.  Eur J Heart Fail  2025 May 19;. doi:10.1002/ejhf.3651
  48. Hermsen M, Lyons PG, Persad G, Bewley AF, Mao C, Chhikara K, Mayampurath A, Churpek M, Peek ME, Luo Y  et al.  Age and Saving Lives in Crisis Standards of Care: A Multicenter Cohort Study of Triage Score Prognostic Accuracy.  Crit Care Explor  2025 May 01;7(5):e1256. pii:e1256
  49. Wang H, Schwirtlich T, Houskamp EJ, Hutch MR, Murphy JX, do Nascimento JS, Zini A, Brancaleoni L, Giacomozzi S, Luo Y  et al.  Automated Detection of Black Hole Sign for Intracerebral Hemorrhage Patients Using Self-Supervised Learning.  AJNR Am J Neuroradiol  2025 May 07;. pii:ajnr.A8826
  50. Pabon MA, Filippatos G, Claggett BL, Miao MZ, Desai AS, Jhund PS, Henderson A, Brinker M, Schloemer P, Hofmeister L  et al.  Finerenone Reduces New-Onset Atrial Fibrillation Across the Spectrum of Cardio-Kidney-Metabolic Syndrome: The FINE-HEART Pooled Analysis.  J Am Coll Cardiol  2025 May 06;85(17):1649-1660. doi:10.1016/j.jacc.2025.03.429

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