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Northwestern University Feinberg School of Medicine
Institute for Artificial Intelligence in Medicine

Publications

Browse the list below to see the latest scientific publications stemming from our institute faculty’s work. To view publications of specific AI faculty, please visit Membership and select a profile link.

  1. Alexander TJ, Gauen AM, Petito LC, Kohli-Lynch CN, Carton TW, Smith SM, Merritt G, Ahmad FS, Allen NB  Hypertension in Young Adults: Social Determinants of Prevalence, Awareness, Treatment, and Control.  Am J Hypertens  2026 Mar 01;39(3):425-431. doi:10.1093/ajh/hpaf203
  2. Henderson AD, Docherty KF, Talebi A, Kondo T, Petrie MC, Claggett BL, Desai AS, Vaduganathan M, Atherton JJ, Bauersachs J  et al.  A Bayesian analysis of finerenone in heart failure with mildly reduced and preserved ejection fraction: a pre-specified analysis of FINEARTS-HF.  Eur Heart J Cardiovasc Pharmacother  2026 Feb 16;. pii:pvag010
  3. Tvedte ES, Arighi C, Carson MB, Rasmussen LV, Holmes K, Murphy TD  Ten quick tips for using the NIH Comparative Genomics Resource.  PLoS Comput Biol  2026 Feb;22(2):e1013919. pii:e1013919
  4. Luo Y  Cardiovascular Endpoint Adjudication in Clinical Trials: A Proactive and Collaborative AI Approach.  J Am Coll Cardiol  2026 Feb 02;. pii:S0735-1097(25)10571-8
  5. Mc Causland FR, Heerspink HJL, Vaduganathan M, Claggett BL, Desai AS, Jhund PS, McGrath MM, Rohwedder K, Amarante F, Brinker M  et al.  Finerenone and eGFR Slope across Different Levels of Baseline Albuminuria and eGFR: Insights from FINEARTS-HF.  Clin J Am Soc Nephrol  2026 Feb 01;21(2):251-260. doi:10.2215/CJN.0000000849
  6. Ostrominski JW, Lu H, Claggett BL, Desai AS, Jhund PS, Henderson AD, Lam CSP, Senni M, Shah SJ, Voors AA  et al.  Interplay Between Heart Failure Events, New-Onset Diabetes, and Finerenone in Heart Failure With Mildly Reduced or Preserved Ejection Fraction.  Diabetes Care  2026 Feb 01;49(2):e12-e14. doi:10.2337/dc25-2540
  7. Ahmad FS, Khan SS, Levin MG  Implementation Intelligence With AI-Prospective Evaluations Needed.  JAMA Cardiol  2026 Feb 01;11(2):125. doi:10.1001/jamacardio.2025.4668
  8. Zhang B, Wu Q, Jhaveri R, Zhou T, Becich MJ, Bisyuk Y, Blanceró F, Chrischilles EA, Chuang CH, Cowell LG  et al.  Long COVID associated with SARS-CoV-2 reinfection among children and adolescents in the omicron era (RECOVER-EHR): a retrospective cohort study.  Lancet Infect Dis  2026 Feb;26(2):127-138. doi:10.1016/S1473-3099(25)00476-1
  9. Ostrominski JW, Filippatos G, Claggett BL, Miao ZM, Desai AS, Jhund PS, Henderson A, Rohwedder K, Brinker MD, Scalise A  et al.  Effect of Finerenone on Morbidity and Mortality in CKD.  J Am Soc Nephrol  2026 Feb 01;37(2):312-325. doi:10.1681/ASN.0000000823
  10. Marrero N, Jha K, Grant J, Razavi AC, Budoff MJ, Shah SJ, Rotter JI, Blumenthal RS, Post WS, Shaw LJ  et al.  Impact of age on aortic valve calcium progression and risk for aortic stenosis: multi-ethnic study of atherosclerosis.  Eur Heart J Cardiovasc Imaging  2026 Jan 30;27(1):1-9. doi:10.1093/ehjci/jeaf279
  11. Butt JH, Henderson AD, Jhund PS, Claggett BL, Desai AS, Borentain M, Rohwedder K, Dayoub R, De Sanctis Y, Lam CSP  et al.  Finerenone, Liver Biomarkers, and Heart Failure With Mildly Reduced/Preserved Ejection Fraction: An Analysis of FINEARTS-HF.  Circ Heart Fail  2026 Jan 29;:e013201. doi:10.1161/CIRCHEARTFAILURE.125.013201
  12. Fontana M, García-Pavía P, Grogan M, Shah SJ, Engelmann MDM, Hovingh GK, Kristen AV, Lim-Watson MZ, Malling B, Kar S  et al.  Coramitug, a Humanized Monoclonal Antibody for the Treatment of Transthyretin Amyloid Cardiomyopathy: A Phase 2, Randomized, Multicenter, Double-Blind, Placebo-Controlled Trial.  Circulation  2026 Jan 27;153(4):214-225. doi:10.1161/CIRCULATIONAHA.125.077304
  13. Petmezas G, Papageorgiou VE, Passman RS, Rogers JA, Stefanopoulos L, Katsaggelos AK, Maglaveras N  Optimizing atrial fibrillation detection through ECG feature selection using Extra-Trees and statistical association measures.  J Electrocardiol  2026 Jan 24;95:154199. doi:10.1016/j.jelectrocard.2026.154199
  14. Verbitsky M, Khosla P, Bivona D, Khan A, Gupta Y, Park H, Shen TH, Ghotra A, Xu K, Ghavami IA  et al.  Urobiota analysis and genome-wide association study in pediatric recurrent urinary tract infections and vesicoureteral reflux.  JCI Insight  2026 Jan 23;11(2). pii:e199689
  15. Salvi C, Luchini SA, Pestilli F, Hanekamp S, Parrish T, Beeman M, Grafman J  The white matter of Aha! moments.  BMC Psychol  2026 Jan 20;14(1):151. pii:151
  16. Lei Y, Zhou T, Zhang B, Zhang D, Tang H, Chen J, Wu Q, Li L, Bailey LC, Becich MJ  et al.  Post-Acute Dyslipidemia and Abnormal Body Mass Index in Children and Adolescents with COVID-19: A Cohort Study from the RECOVER Initiative.  J Pediatr  2026 Jan 19;291:114996. doi:10.1016/j.jpeds.2026.114996
  17. Michelson KN, Hayes A, Barrera L, James K, Miller C, Guzman Z, Torres N, McNicholas A, Becker AB  Pilot Study of a Bereavement Referral Program for Parents Following Perinatal Death.  J Pain Symptom Manage  2026 Jan 18;. pii:S0885-3924(26)00006-0
  18. Girard AA, Mylavarapu U, Komtebedde J, Arnold SV, Solomon SD, Leon MB, Van Veldhuisen DJ, Cutlip DE, Cikes M, Zile MR  et al.  Estimating the Placebo Effect on Patient-Reported Outcomes in Sham-controlled Device Trials: Insights from REDUCE LAP-HF II.  Circ Popul Health Outcomes  2026 Jan 12;. doi:10.1161/circoutcomes.125.012676
  19. Frank SJ, Busse PM, Lee JJ, Rosenthal DI, Hernandez M, Swanson DM, Garden AS, Gunn GB, Patel SH, Snider JW  et al.  Proton versus photon radiotherapy for patients with oropharyngeal cancer in the USA: a multicentre, randomised, open-label, non-inferiority phase 3 trial.  Lancet  2026 Jan 10;407(10524):174-184. doi:10.1016/S0140-6736(25)01962-2
  20. Wang K, Wang J, Weiss MJ, Yue F, Xu J  Disrupting epigenetic insulation underlies CRISPR therapy for β-hemoglobinopathies.  Mol Ther  2026 Jan 07;34(1):35-37. doi:10.1016/j.ymthe.2025.12.015
  21. Li D, Liu S, Assis PR, Li M, Dong S, Whaling I, Jolanki O, Kagda M, Zhang W, Macias-Velasco JF  et al.  The IGVF catalog-from genetic variation to function.  Nucleic Acids Res  2026 Jan 06;54(D1):D1437-D1445. doi:10.1093/nar/gkaf1341
  22. Yu S, Fu Y, Wong JH, Wang J, Zhao H, Zhao J, Yue F  The 3D Genome Browser 2.0: an enhanced online platform for visualizing and analyzing 3D genome architecture.  Nucleic Acids Res  2026 Jan 06;54(D1):D48-D54. doi:10.1093/nar/gkaf1109
  23. Kremer N, Polo-Silveira L, Bajaj S, Sattler S, Halpern AC, Bagci U, Dusza SW, Kose K, Weber J, D'Alessandro B  et al.  Comparing dermatologists' and artificial intelligence heat maps in dermoscopic image analysis via eye tracking.  J Am Acad Dermatol  2026 Jan 03;. pii:S0190-9622(25)03490-5
  24. Dekker J, Oksuz BA, Zhang Y, Wang Y, Minsk MK, Kuang S, Yang L, Gibcus JH, Krietenstein N, Rando OJ  et al.  An integrated view of the structure and function of the human 4D nucleome.  Nature  2026 Jan;649(8097):759-776. doi:10.1038/s41586-025-09890-3
  25. Zelicha H, Weitzner ZN, Park S, Babb TG, Bernhardt V, Ahmad FS, Cella D, Chen Y, Livingston EH  Improvement in breathlessness following bariatric surgery as measured by a new heart failure-specific health-related quality of life instrument: a prospective longitudinal study.  Surg Obes Relat Dis  2026 Jan;22(1):137-144. doi:10.1016/j.soard.2025.09.014
  26. Vaduganathan M, Claggett BL, Chatur S, Desai AS, Jhund PS, Vardeny O, Merkely B, Martinez F, Comin-Colet J, Kerr Saraiva JF  et al.  Lifetime benefits of comprehensive medical therapy in heart failure with mildly reduced or preserved ejection fraction.  Nat Med  2026 Jan;32(1):325-331. doi:10.1038/s41591-025-04037-3
  27. Philbin SE, Gleason LP, Persell SD, Walter E, Petito LC, Tibrewala A, Yancy CW, Beidas RS, Wilcox JE, Mutharasan RK  et al.  Barriers and Facilitators to Heart Failure Guideline-Directed Medical Therapy in an Integrated Health System and Federally Qualified Health Centers: A Thematic Qualitative Analysis.  J Gen Intern Med  2026 Jan;41(2):480-488. doi:10.1007/s11606-025-09515-5
  28. Ostrominski JW, Vaduganathan M, Claggett BL, Desai AS, Jhund PS, Lam CSP, Senni M, Shah SJ, Voors AA, Zannad F  et al.  Finerenone and NYHA Functional Class in Heart Failure: The FINEARTS-HF Trial.  JACC Heart Fail  2026 Jan;14(1):102440. doi:10.1016/j.jchf.2025.03.007
  29. Ostrominski JW, Mc Causland FR, Claggett BL, Desai AS, Jhund PS, Lam CSP, Senni M, Shah SJ, Voors AA, Zannad F  et al.  Finerenone Across the Spectrum of Kidney Risk in Heart Failure: The FINEARTS-HF Trial.  JACC Heart Fail  2026 Jan;14(1):102439. doi:10.1016/j.jchf.2025.03.006
  30. Banker M, do Nascimento JSP, Shownkeen H, Chang TR, Goldenberg F, Faine B, Cella D, Schuele SU, Luo Y, Tipton E  et al.  Prophylactic Antiseizure Medication in Patients with Lobar Intracerebral Hemorrhage.  Neurocrit Care  2025 Dec 18;. doi:10.1007/s12028-025-02423-w
  31. Zhu F, Sinha A, Graça G, Neeland IJ, Pandey A, Tzoulaki I, Karaman I, Tracy RP, Lima JAC, Shah SJ  et al.  Serum Metabolites and Heart Failure Risk: MESA and RS.  J Am Heart Assoc  2025 Dec 16;14(24):e044211. pii:e044211
  32. Foà A, Vaduganathan M, Claggett BL, Desai AS, Jhund PS, Henderson AD, Chatur S, Amarante F, Hofmeister L, Horvat-Broecker A  et al.  Finerenone-Related Risk of Hypotension in Heart Failure With Mildly Reduced or Preserved Ejection Fraction.  JACC Heart Fail  2025 Dec 06;:102779. doi:10.1016/j.jchf.2025.102779
  33. Wong AF, Bilaver LA, Jiang J, Luo Y, Gupta RS, Rosenman M, Carroll MS  Assessing pediatric clinician adherence to the guidelines for prevention of peanut allergy: a natural language processing study.  BMC Med Inform Decis Mak  2025 Dec 06;26(1):9. pii:9
  34. Mc Causland FR, Chatur S, Vaduganathan M, Claggett BL, Kulac IJ, Desai AS, Jhund PS, Henderson AD, Rohwedder K, Amarante F  et al.  Finerenone and Cardiovascular Outcomes According to Baseline Kidney Function in Patients With Heart Failure: The FINEARTS-HF Trial.  JACC Heart Fail  2025 Dec 05;:102778. doi:10.1016/j.jchf.2025.102778
  35. Guare LA, Das J, Caruth L, Rajagopalan A, Akerele AT, Brumpton BM, Chen TT, Kottyan L, Lin YF, Moreno E  et al.  Expanding the genetic landscape of endometriosis: Integrative -omics analyses implicate key genes and pathways in a multi-ancestry study of over one million women.  Res Sq  2025 Dec 04;. pii:rs.3.rs-8116602
  36. Borlaug BA, Chirinos JA, Lewis GD, Redfield MM, Bertoni AG, Cadeiras M, Chiamvimonvat N, Desai AS, Givertz MM, Kass DA  et al.  Rationale and Design of the HeartShare/AMP-HF Deep Phenotyping Study to Improve Understanding of Heart Failure With Preserved Ejection Fraction.  JACC Heart Fail  2025 Dec;13(12):102714. doi:10.1016/j.jchf.2025.102714
  37. Abahuje E, Houskamp EJ, Silva Pinheiro do Nascimento J, Agha EM, Thompson WK, Michelson KN, Naidech A  Patient and clinician perspectives in the use of machine learning and artificial intelligence in the context of acute neurology.  JAMIA Open  2025 Dec;8(6):ooaf143. pii:ooaf143
  38. Inciardi RM, Lu H, Claggett BL, Desai AS, Jhund PS, Henderson AD, Lam CSP, Merkely B, Miao MZ, Senni M  et al.  Finerenone in patients with severe heart failure: The FINEARTS-HF trial.  Eur J Heart Fail  2025 Dec;27(12):2777-2787. doi:10.1002/ejhf.70083
  39. Ahmad FS, Wehbe RM, Wilcox JE  The SCAI Is Not the Limit: Refining Dynamic Shock Trajectories With Machine Learning-Based Phenotyping.  JACC Heart Fail  2025 Dec;13(12):102700. doi:10.1016/j.jchf.2025.102700
  40. Nateghi R, Zhou R, Saft M, Schnauss M, Neill C, Alam R, Handa N, Huang M, Li EV, Goldstein JA  et al.  Artificial Intelligence (AI)-Driven Screening of Equivocal Prostate Immunohistochemistry (IHC) Cases: Development and Validation of a Screening and Cancer Detection Framework.  Mod Pathol  2025 Dec;38(12):100904. doi:10.1016/j.modpat.2025.100904
  41. Ostrominski JW, Claggett BL, Desai AS, Jhund PS, Lam CSP, Senni M, Shah SJ, Voors AA, Zannad F, Pitt B  et al.  Finerenone according to insulin resistance in heart failure: Insights from the FINEARTS-HF trial.  Eur J Heart Fail  2025 Dec;27(12):2788-2799. doi:10.1002/ejhf.70034
  42. Crum Y, van Veldhuisen DJ, Shah SJ, Mylavarapu U, Hu M, Komtebedde J, Lobeek M, Hoendermis ES, Litwin SE, Solomon SD  et al.  Epicardial Adipose Tissue, Functional Status, and Invasive Hemodynamics in Heart Failure With Preserved Ejection Fraction.  JACC Adv  2025 Dec;4(12 Pt 2):102185. pii:102185
  43. Weerts J, Barandiarán Aizpurua A, Patel RB, van de Bovenkamp AA, Amin H, Sanders-van Wijk S, Mourmans SGJ, Achten A, Handoko ML, Bayés-Genís A  et al.  A simplified approach for diagnosing heart failure with preserved ejection fraction by assessing the left atrium and natriuretic peptides.  Eur J Heart Fail  2025 Dec;27(12):2897-2902. doi:10.1002/ejhf.3651
  44. Gyberg DJ, Komtebedde J, Mylavarapu U, Litwin SE, Leon MB, Cutlip DE, Solomon SD, Starling RC, Cikes M, Borlaug BA  et al.  Refining Atrial Shunt Therapy for HFpEF: Lessons from Pivotal Randomized Trials and Emerging Directions.  J Card Fail  2025 Nov 29;. pii:S1071-9164(25)00436-1
  45. Shimano KA, Grimes AB, Kaicker S, Shah SJ, Gunn E, Bhat RV, Kochhar M, Rothman JA, Rose MJ, Briones M  et al.  Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment: The PINES Randomized Clinical Trial.  JAMA  2025 Nov 25;334(20):1816-1826. doi:10.1001/jama.2025.18168
  46. Samadian KD, Chua E, Peng B, Coleska A, Hassan A, Chong P, Locke B, Liebovitz DM, Rohlfsen C, He S  Entropy removal of clinical features.  Sci Rep  2025 Nov 23;15(1):45182. pii:45182
  47. Ostrominski JW, Neuen BL, Claggett BL, Filippatos G, Desai AS, Jhund PS, Henderson A, Lam CSP, Senni M, Shah SJ  et al.  Timing of Cardiovascular and Kidney Benefits With Finerenone in Heart Failure and Chronic Kidney Disease With Type 2 Diabetes.  J Am Coll Cardiol  2025 Nov 18;. pii:S0735-1097(25)10071-5
  48. Ostrominski JW, Harrington J, Claggett BL, Filippatos G, Desai AS, Jhund PS, Henderson AD, Lam CSP, Senni M, Shah SJ  et al.  Anthropometric Measures, Cardiovascular Outcomes, and Treatment Effects of Finerenone in Cardiovascular-Kidney-Metabolic Disease: Pooled Participant-Level Analysis of 3 Global Trials.  J Am Coll Cardiol  2025 Nov 18;86(20):1781-1801. doi:10.1016/j.jacc.2025.08.039
  49. Desai AS, Pandey A, Suratekar R, Ahmad FS, Alger HM, Anto AG, Nujum G S, Lopez-Jimenez F, Oh JK, Asfahan S  et al.  Predicting Heart Failure From 12-Lead ECGs Using AI: A HeartShare/AMP-HF Pooled Cohort Analysis.  J Am Coll Cardiol  2025 Nov 08;. pii:S0735-1097(25)10079-X
  50. Wang H, Schwirtlich T, Houskamp E, Hutch M, Murphy J, Nascimento JSPD, Zini A, Brancaleoni L, Giacomozzi S, Luo Y  et al.  Automated Detection of the Black Hole Sign for Patients with Intracerebral Hemorrhage Using Self-Supervised Learning.  AJNR Am J Neuroradiol  2025 Nov 03;46(11):2300-2309. doi:10.3174/ajnr.A8826

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