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Northwestern University Feinberg School of Medicine
Institute for Artificial Intelligence in Medicine

Publications

Browse the list below to see the latest scientific publications stemming from our institute faculty’s work. To view publications of specific AI faculty, please visit Membership and select a profile link.

  1. Kruzan KP, Ammerman B, Lengel GJ, Griffith JW, Lucas K, Nguyen T, Rushton K, Washburn JJ, Mohr DC  Development and initial test of an online self-assessment of nonsuicidal self-injury severity.  J Affect Disord  2025 Oct 15;387:119506. doi:10.1016/j.jad.2025.119506
  2. Dennis S, Tsukioki T, Kocherginsky M, Qi AK, DeHorn S, Gurley M, Wrubel E, Luo Y, Khan SA  ASO Visual Abstract: Neoadjuvant Chemotherapy Response and Genetic Susceptibility in Recently Parous Women with Breast Cancer: A Retrospective Analysis.  Ann Surg Oncol  2025 Jul;32(7):4916-4917. doi:10.1245/s10434-025-17370-1
  3. Dennis S, Tsukioki T, Kocherginsky M, Qi AK, DeHorn S, Gurley M, Wrubel E, Luo Y, Khan SA  Neoadjuvant Chemotherapy Response and Genetic Susceptibility in Recently Parous Women with Breast Cancer: A Retrospective Analysis.  Ann Surg Oncol  2025 Jul;32(7):4855-4864. doi:10.1245/s10434-025-17204-0
  4. Li M, Fass OZ, Carlson DA, Pitisuttithum P, Goudie E, Kristinsdottir K, Kaklamanos E, Etemadi M, Keswani RN, Ellison A  et al.  Endoscopic Prediction of Achalasia: Putting the CART Before the CARS.  Neurogastroenterol Motil  2025 Jul;37(7):e70024. pii:e70024
  5. Hosseini M, Holcombe AO, Kovacs M, Zwart H, Katz DS, Holmes K  Group authorship, an excellent opportunity laced with ethical, legal and technical challenges.  Account Res  2025 Jul;32(5):762-784. doi:10.1080/08989621.2024.2322557
  6. Ding Y, He B, Bogush D, Schramm J, Singh C, Dovat K, Randazzo J, Tukaramrao D, Hengst J, Annageldiyev C  et al.  Critical roles of IKAROS and HDAC1 in regulation of heterochromatin and tumor suppression in T-cell acute lymphoblastic leukemia.  Leukemia  2025 Jun 24;. doi:10.1038/s41375-025-02651-1
  7. Herrold AA, Aaronson AL, Bhaumik D, Durazzo T, Livengood SL, Ramic A, Riordan P, Jordan N, Parrish T, Mallinson T  et al.  A Customized Neural Transcranial Magnetic Stimulation Target for Functional Disability Among Veterans With Co-Occurring Alcohol Use Disorder and Mild Traumatic Brain Injury: Protocol for a Pilot Randomized Controlled Trial.  JMIR Res Protoc  2025 Jun 23;14:e64909. doi:10.2196/64909
  8. Klein L, Fudim M, Etemadi M, Gordon R, Tibrewala A, Hernandez-Montfort J, McCann P, Zier L, Shah K, Rollins A  et al.  Noninvasive Pulmonary Capillary Wedge Pressure Estimation in Heart Failure Patients With the Use of Wearable Sensing and AI.  JACC Heart Fail  2025 Jun 20;13(8):102513. doi:10.1016/j.jchf.2025.102513
  9. Butt JH, Jhund PS, Henderson AD, Claggett BL, Chiang CE, Linssen GCM, Saldarriaga CI, Saraiva JFK, Sato N, Schou M  et al.  Finerenone According to Frailty in Heart Failure: A Prespecified Analysis of the FINEARTS-HF Randomized Clinical Trial.  JAMA Cardiol  2025 Jun 18;. pii:e251775
  10. Bisen JB, Sikora H, Aneja A, Shah SJ, Mirza RG  Retinal Imaging as a Window into Cardiovascular Health: Towards Harnessing Retinal Analytics for Precision Cardiovascular Medicine.  J Cardiovasc Dev Dis  2025 Jun 17;12(6). pii:230
  11. Li Y, Ding Y, Dennis S, Hutch MR, Zhou J, Zhou Y, Li Y, Pillai M, Ghotbaldini S, Garcia MA  et al.  SOAR elucidates biological insights and empowers drug discovery through spatial transcriptomics.  Sci Adv  2025 Jun 13;11(24):eadt7450. doi:10.1126/sciadv.adt7450
  12. Ostrominski JW, Filippatos G, Claggett BL, Miao ZM, Desai AS, Jhund PS, D Henderson A, Scheerer MF, Rohwedder K, Amarante F  et al.  Efficacy and Safety of Finerenone in Heart Failure With Preserved Ejection Fraction: A FINE-HEART Analysis.  JACC Heart Fail  2025 Jun 11;13(8):102497. doi:10.1016/j.jchf.2025.03.041
  13. Dennis SR, Tsukioki T, Cottone G, Zhou W, Ganz PA, Sehl ME, Luo Y, Khan SA, Clare S  DNA methylation patterns in breast cancer, paired benign tissue from ipsilateral and contralateral breast, and healthy controls.  Breast Cancer Res  2025 Jun 11;27(1):103. pii:103
  14. Mithal LB, Becker ME, Ling-Hu T, Goo YA, Otero S, Kremer A, Pandey S, Lancki N, Li Y, Luo Y  et al.  Cord blood proteomics identifies biomarkers of early-onset neonatal sepsis.  JCI Insight  2025 Jun 10;. pii:e193826
  15. Ozyoruk KB, Harmon SA, Yilmaz EC, Gelikman DG, Bagci U, Simon BD, Merino MJ, Lis R, Gurram S, Wood BJ  et al.  Impact of AI-Generated ADC Maps on Computer-Aided Diagnosis of Prostate Cancer: A Feasibility Study.  Acad Radiol  2025 Jun 04;. pii:S1076-6332(25)00518-5
  16. Huang J, Wittbrodt MT, Teague CN, Karl E, Galal G, Thompson M, Chapa A, Chiu ML, Herynk B, Linchangco R  et al.  Efficiency and Quality of Generative AI-Assisted Radiograph Reporting.  JAMA Netw Open  2025 Jun 02;8(6):e2513921. pii:e2513921
  17. Rambarat P, DeVore AD, Bhatt AS, Allen LA, McIlvennan CK, Cotter G, Mukhopadhyay A, Ahmad T, Ahmad FS, Psotka MA  Failure to Launch: Insights From Randomized Trials on Implementation Strategies for Guideline-Directed Therapies for Heart Failure.  JACC Heart Fail  2025 Jun;13(6):887-900. doi:10.1016/j.jchf.2025.02.023
  18. Sehgal S, Starren J, Cattin K, Bilaver L, Gururaj A, Togias A, Gupta RS  Common data elements for food allergy clinical trials: an overview.  Curr Opin Allergy Clin Immunol  2025 Jun 01;25(3):194-198. doi:10.1097/ACI.0000000000001075
  19. Brokamp E, Miller-Fleming T, Scalici A, Hooker G, Hamid R, Velez Edwards D, Chung WK, Luo Y, Kiryluk K, Limidi NA  et al.  Systematic method for classifying multiple congenital anomaly cases in electronic health records.  Genet Med  2025 Jun;27(6):101415. doi:10.1016/j.gim.2025.101415
  20. Sandlow S, Carbunaru S, Sun Z, Ofori B, Liu Y, Li E, Hollowell CMP, Vidal P, Perry KT, Patel HD  et al.  Negative Predictive Value of a Prostate MRI in Black Men: Implications for Biopsy Decision-Making.  J Urol  2025 Jun;213(6):713-721. doi:10.1097/JU.0000000000004498
  21. Armoundas AA, Ahmad FS, Attia ZI, Doudesis D, Khera R, Kyriakoulis KG, Stergiou GS, Tang WHW  Controversy in Hypertension: Pro-Side of the Argument Using Artificial Intelligence for Hypertension Diagnosis and Management.  Hypertension  2025 Jun;82(6):929-944. doi:10.1161/HYPERTENSIONAHA.124.22349
  22. Pandey A, Lewis GD, Borlaug BA, Shah SJ, Sauer AJ, Litwin S, Sharma K, Jorkasky DK, Tarka EA, Khan SM  et al.  Novel Controlled Metabolic Accelerator for Obesity-Related HFpEF: The HuMAIN-HFpEF Randomized Clinical Trial.  JAMA Cardiol  2025 Jun 01;10(6):609-616. doi:10.1001/jamacardio.2025.0103
  23. Tavolinejad H, Boczar KE, Spronck B, Maynard H, Bertoni AG, Shah SJ, Chirinos JA  Determinants of Cardio-Ankle Vascular Index and Heart-Thigh β Index in the MESA.  Hypertension  2025 Jun;82(6):1081-1094. doi:10.1161/HYPERTENSIONAHA.124.23970
  24. McDowell K, Docherty KF, Campbell RT, Henderson AD, Jhund PS, Claggett BL, Desai AS, Lay-Flurrie J, Hofmeister L, Scalise A  et al.  Finerenone for Heart Failure and Risk Estimated by the PREDICT-HFpEF Model: A Secondary Analysis of FINEARTS-HF.  JAMA Cardiol  2025 Jun 01;10(6):535-544. doi:10.1001/jamacardio.2025.0025
  25. Ambrosy AP, Sauer AJ, Patel S, Windsor SL, Borlaug BA, Husain M, Inzucchi SE, Kitzman DW, McGuire DK, Shah SJ  et al.  Baseline kidney function and the effects of dapagliflozin on health status in heart failure in DEFINE-HF and PRESERVED-HF.  ESC Heart Fail  2025 Jun;12(3):1676-1681. doi:10.1002/ehf2.15184
  26. Michelson KN, Fishman AC, Feinberg EC, Ross S, Wald HS, Auerbach C, Roth S  Antisemitism in American Healthcare: A Survey Study of Reported Experiences.  J Gen Intern Med  2025 Jun;40(8):1940-1943. doi:10.1007/s11606-024-09159-x
  27. Hasjim BJ, Mohammadi M, Balbale SN, Paukner M, Banea T, Shi H, Furmanchuk A, VanWagner LB, Zhao L, Duarte-Rojo A  et al.  High Hospitalization Rates and Risk Factors Among Frail Patients With Cirrhosis: A 10-year Population-based Cohort Study.  Clin Gastroenterol Hepatol  2025 Jun;23(7):1152-1163. doi:10.1016/j.cgh.2024.08.044
  28. Goldstein JA, Nateghi R, Cooper LAD  Machine Learning Assessment of Gestational Age in Accelerated Maturation, Delayed Maturation, Villous Edema, Chorangiosis, and Intrauterine Fetal Demise.  Arch Pathol Lab Med  2025 Jun 01;149(6):503-510. doi:10.5858/arpa.2024-0274-OA
  29. Barrett MA, Allen A, Vuong VT, Zhu D, Rainey AJ, McConnell WM, Kho AN, Salisbury A, French DD  Impact of an Artificial Intelligence and Machine Learning Enhanced Electronic Health Record System on Quality Measures in Nursing Homes: A Difference-in-Differences Analysis.  J Am Med Dir Assoc  2025 May 28;26(7):105680. doi:10.1016/j.jamda.2025.105680
  30. Agha E, Sutter C, Ojewuyi I, Abramsohn EM, Andriano M, Bell C, Calix AL, Cherry JL, Downing K, Flower T  et al.  The Grief Navigation Trial: A multi-site pragmatic comparative effectiveness trial of two interventions to support parents after their child's unexpected or traumatic death.  Contemp Clin Trials  2025 May 26;155:107962. doi:10.1016/j.cct.2025.107962
  31. Wang M, Liu Z, Ren S, Zhu J, Morisawa N, Chua GL, Zhang X, Wong YK, Su L, Wong MX  et al.  BCAA catabolism targeted therapy for heart failure with preserved ejection fraction.  Theranostics  2025;15(13):6257-6273. doi:10.7150/thno.105894
  32. Lefer DJ, Sharp TE, Scarborough AL, Haydel AG, Shah SJ, Li Z, Goodchild TT  Renal denervation improves cardiac function and exercise duration in a miniswine model of heart failure with preserved ejection fraction.  Eur J Heart Fail  2025 May 22;. doi:10.1002/ejhf.3700
  33. Pabon MA, Vardeny O, Vaduganathan M, Desai AS, Claggett BL, Kulac IJ, Jhund PS, Lam CSP, Senni M, Shah SJ  et al.  Finerenone in Heart Failure With Improved Ejection Fraction: The FINEARTS-HF Randomized Clinical Trial.  JAMA Cardiol  2025 May 21;. pii:e251101
  34. Filipp M, Ge ZD, DeBerge M, Lantz C, Glinton K, Gao P, Smolgovsky S, Dai J, Zhao YY, Yvan-Charvet L  et al.  Myeloid Fatty Acid Metabolism Activates Neighboring Hematopoietic Stem Cells to Promote Heart Failure With Preserved Ejection Fraction.  Circulation  2025 May 20;151(20):1451-1466. doi:10.1161/CIRCULATIONAHA.124.070248
  35. Jha D, Durak G, Das A, Sanjotra J, Susladkar O, Sarkar S, Rauniyar A, Kumar Tomar N, Peng L, Li S  et al.  Ethical framework for responsible foundational models in medical imaging.  Front Med (Lausanne)  2025;12:1544501. pii:1544501
  36. Keles E, Ali SY, Wintermark P, Annaert P, Groenendaal F, Şahin S, Öncel MY, Armangil D, Koc E, Battin MR  et al.  Machine learning based clinical decision tool to predict acute kidney injury and survival in therapeutic hypothermia treated neonates.  Sci Rep  2025 May 19;15(1):17278. pii:17278
  37. Weerts J, Barandiarán Aizpurua A, Patel RB, van de Bovenkamp AA, Amin H, Sanders-van Wijk S, Mourmans SGJ, Achten A, Handoko ML, Bayés-Genís A  et al.  A simplified approach for diagnosing heart failure with preserved ejection fraction by assessing the left atrium and natriuretic peptides.  Eur J Heart Fail  2025 May 19;. doi:10.1002/ejhf.3651
  38. Hermsen M, Lyons PG, Persad G, Bewley AF, Mao C, Chhikara K, Mayampurath A, Churpek M, Peek ME, Luo Y  et al.  Age and Saving Lives in Crisis Standards of Care: A Multicenter Cohort Study of Triage Score Prognostic Accuracy.  Crit Care Explor  2025 May 01;7(5):e1256. pii:e1256
  39. Wang H, Schwirtlich T, Houskamp EJ, Hutch MR, Murphy JX, do Nascimento JS, Zini A, Brancaleoni L, Giacomozzi S, Luo Y  et al.  Automated Detection of Black Hole Sign for Intracerebral Hemorrhage Patients Using Self-Supervised Learning.  AJNR Am J Neuroradiol  2025 May 07;. pii:ajnr.A8826
  40. Pabon MA, Filippatos G, Claggett BL, Miao MZ, Desai AS, Jhund PS, Henderson A, Brinker M, Schloemer P, Hofmeister L  et al.  Finerenone Reduces New-Onset Atrial Fibrillation Across the Spectrum of Cardio-Kidney-Metabolic Syndrome: The FINE-HEART Pooled Analysis.  J Am Coll Cardiol  2025 May 06;85(17):1649-1660. doi:10.1016/j.jacc.2025.03.429
  41. Braumann S, Macherey-Meyer S, Polzin A, Costard-Jäckle A, Morbach C, Haring B, Lapp H, Ten Cate V, Gieswinkel A, Weliwitage J  et al.  MYSTERY-HF: Myeloperoxidase Inhibition in Patients With Heart Failure and Reduced Ejection Fraction: A Phase II Randomized Controlled Trial.  Circulation  2025 May 06;151(18):1372-1374. doi:10.1161/CIRCULATIONAHA.125.074085
  42. Smith JD, Carroll AJ, Tedla YG, Sanuade OA, Merle JL, Heinrich J, Bannon J, Abramsohn EM, Ahmad FS, Lazar D  et al.  Community intervention to reduce cardiovascular disease in Chicago (CIRCL-Chicago): protocol for a type 3 hybrid effectiveness-implementation study using a parallel cluster-randomized trial design.  Implement Sci  2025 May 05;20(1):19. pii:19
  43. Philbin SE, Gleason LP, Persell SD, Walter E, Petito LC, Tibrewala A, Yancy CW, Beidas RS, Wilcox JE, Mutharasan RK  et al.  Barriers and Facilitators to Heart Failure Guideline-Directed Medical Therapy in an Integrated Health System and Federally Qualified Health Centers: A Thematic Qualitative Analysis.  J Gen Intern Med  2025 May 05;. doi:10.1007/s11606-025-09515-5
  44. Culler K, Zelnick LR, Mehta RC, de Sosa GR, Kansal M, Rao PS, Bhat Z, Taliercio J, Horwitz E, Chen J  et al.  The ICAM1 p.K56M variant and risk of heart failure in chronic kidney disease: the Chronic Renal Insufficiency Cohort study.  Heart  2025 May 02;111(10):441-444. doi:10.1136/heartjnl-2024-325205
  45. Berhane H, Maroun A, Dushfunian D, Baraboo J, Martinez G, Jacobson T, Bagci U, Allen BD, Markl M  Anatomy-derived 3D Aortic Hemodynamics Using Fluid Physics-informed Deep Learning.  Radiology  2025 May;315(2):e240714. pii:e240714
  46. Ostrominski JW, Claggett BL, Miao ZM, Filippatos G, Desai AS, Jhund PS, Henderson A, Brinker M, Schloemer P, Viswanathan P  et al.  Efficacy and Safety of Finerenone in Type 2 Diabetes: A Pooled Analysis of Trials of Heart Failure and Chronic Kidney Disease.  Diabetes Care  2025 May 01;48(5):745-755. doi:10.2337/dc24-1873
  47. Chen C, Nishtala A, Li E, Schultz WM, Baldridge AS, Groenendyk JW, Lee DC, Shah SJ, Burt RK, Freed BH  The effect of hematopoietic stem cell transplantation on cardiac mechanics in systemic sclerosis.  Int J Cardiovasc Imaging  2025 May;41(5):879-887. doi:10.1007/s10554-025-03365-2
  48. Friedewald SM, Sieniek M, Jansen S, Mahvar F, Kohlberger T, Schacht D, Bhole S, Gupta D, Prabhakara S, McKinney SM  et al.  Triaging mammography with artificial intelligence: an implementation study.  Breast Cancer Res Treat  2025 May;211(1):1-10. doi:10.1007/s10549-025-07616-7
  49. Li EV, Ren Y, Griffin J, Han J, Yamashita R, Mitani A, Zhou R, Huang HC, Yang X, Feng FY  et al.  An Artificial Intelligence-Digital Pathology Algorithm Predicts Survival After Radical Prostatectomy From the Prostate, Lung, Colorectal, and Ovarian Cancer Trial.  J Urol  2025 May;213(5):600-608. doi:10.1097/JU.0000000000004435
  50. Stefanopoulos L, Kim BW, Sheppard J, Azcona EA, Vike NL, Bari S, Lalvani S, Woodward S, Maglaveras N, Block M  et al.  Discrete, recurrent, and scalable patterns in non-operant judgement underlie affective picture ratings.  Cogn Process  2025 May;26(2):257-281. doi:10.1007/s10339-024-01250-9

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