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Northwestern University Feinberg School of Medicine
Institute for Artificial Intelligence in Medicine

Publications

Browse the list below to see the latest scientific publications stemming from our institute faculty’s work. To view publications of specific AI faculty, please visit Membership and select a profile link.

  1. Kruzan KP, Ammerman B, Lengel GJ, Griffith JW, Lucas K, Nguyen T, Rushton K, Washburn JJ, Mohr DC  Development and initial test of an online self-assessment of nonsuicidal self-injury severity.  J Affect Disord  2025 Oct 15;387:119506. doi:10.1016/j.jad.2025.119506
  2. Cai FY, Mao C, Luo Y  Constrained Tensor Factorization for Cancer Phenotyping and Mortality Prediction.  Stud Health Technol Inform  2025 Aug 07;329:871-875. doi:10.3233/SHTI250964
  3. Khan SS, Harrington RA, Ahmad FS  Blood Pressure Measurement in Retail Stores and Population Health.  JAMA Cardiol  2025 Aug 06;. doi:10.1001/jamacardio.2025.2492
  4. Vaduganathan M, Claggett BL, Udell JA, Desai AS, Jhund PS, Henderson AD, Lay-Flurrie J, Amarante F, Glasauer A, Lam CSP  et al.  Blinded Withdrawal of Finerenone After Long-Term Treatment in the FINEARTS-HF Trial.  J Am Coll Cardiol  2025 Aug 05;86(5):396-399. doi:10.1016/j.jacc.2025.05.038
  5. Luo Z, Xia M, Shi W, Zhao C, Wang J, Xin D, Dong X, Xiong Y, Zhang F, Berry K  et al.  Retraction Note: Human fetal cerebellar cell atlas informs medulloblastoma origin and oncogenesis.  Nature  2025 Aug;644(8075):290. doi:10.1038/s41586-025-09015-w
  6. Ding Y, He B, Bogush D, Schramm J, Singh C, Dovat K, Randazzo J, Tukaramrao D, Hengst J, Annageldiyev C  et al.  Critical roles of IKAROS and HDAC1 in regulation of heterochromatin and tumor suppression in T-cell acute lymphoblastic leukemia.  Leukemia  2025 Aug;39(8):2010-2020. doi:10.1038/s41375-025-02651-1
  7. Klein L, Fudim M, Etemadi M, Gordon R, Tibrewala A, Hernandez-Montfort J, McCann P, Zier L, Shah K, Rollins A  et al.  Noninvasive Pulmonary Capillary Wedge Pressure Estimation in Heart Failure Patients With the Use of Wearable Sensing and AI.  JACC Heart Fail  2025 Aug;13(8):102513. doi:10.1016/j.jchf.2025.102513
  8. Ostrominski JW, Filippatos G, Claggett BL, Miao ZM, Desai AS, Jhund PS, D Henderson A, Scheerer MF, Rohwedder K, Amarante F  et al.  Efficacy and Safety of Finerenone in Heart Failure With Preserved Ejection Fraction: A FINE-HEART Analysis.  JACC Heart Fail  2025 Aug;13(8):102497. doi:10.1016/j.jchf.2025.03.041
  9. Ozyoruk KB, Harmon SA, Yilmaz EC, Gelikman DG, Bagci U, Simon BD, Merino MJ, Lis R, Gurram S, Wood BJ  et al.  Impact of AI-Generated ADC Maps on Computer-Aided Diagnosis of Prostate Cancer: A Feasibility Study.  Acad Radiol  2025 Aug;32(8):4621-4630. doi:10.1016/j.acra.2025.05.041
  10. Agha E, Sutter C, Ojewuyi I, Abramsohn EM, Andriano M, Bell C, Calix AL, Cherry JL, Downing K, Flower T  et al.  The Grief Navigation Trial: A multi-site pragmatic comparative effectiveness trial of two interventions to support parents after their child's unexpected or traumatic death.  Contemp Clin Trials  2025 Aug;155:107962. doi:10.1016/j.cct.2025.107962
  11. Hoffmann AD, Almubarak HF, Iyer R, Weinberg SE, Squires JR, Mao C, Wei J, Chaudhuri S, El-Shennawy L, Dashzeveg NK  et al.  Identification of immune signatures associated with both SARS-CoV-2 infection and lung transplantation.  Cell Rep Med  2025 Jul 29;:102262. doi:10.1016/j.xcrm.2025.102262
  12. Chaudhary RS, Hussain SMD, Wang YS, Komtebedde J, Hasenfuß G, Borlaug BA, Kaye DM, Cleland JGF, Leon MB, Shah SJ  et al.  Expanded Definition of Worsening Heart Failure: Impact on Clinical Outcomes and Quality-of-Life Assessment.  JACC Heart Fail  2025 Jul 25;13(9):102571. doi:10.1016/j.jchf.2025.102571
  13. Yaku H, Sauer AJ, Patel S, O'Keefe EL, Borlaug BA, Kitzman DW, Windsor SL, Khumri T, Umpierrez G, Kosiborod MN  et al.  Orthostatic Pulse Pressure as a Potential Indicator of Preload Insufficiency in HFpEF: Insights From PRESERVED-HF.  JACC Heart Fail  2025 Jul 25;13(9):102566. doi:10.1016/j.jchf.2025.102566
  14. Saleiro D, Wen JQ, Zannikou M, Lee B, Kosciuczuk EM, Nehlsen SD, Munshi A, Chen X, Oku CV, Hryhorysak B  et al.  Loss of Function Mouse Models Reveal a Novel Regulatory Function for ULK1 in Myeloproliferative Neoplasms.  Mol Cell Biol  2025 Jul 23;:1-24. doi:10.1080/10985549.2025.2529837
  15. Yaku H, Shah SJ  The Key Role of Diagnostic Imaging in Early HFpEF.  JACC Cardiovasc Imaging  2025 Jul 17;. pii:S1936-878X(25)00306-7
  16. Wang MC, Dolan B, Huang X, Freaney PM, Freed BH, Vega L, Markoski N, Wainright A, Kane B, Seegmiller LE  et al.  Feasibility of the Implementation of Tools for Heart Failure Risk Prediction: A Randomized Controlled Pilot Trial.  JACC Adv  2025 Jul 14;4(8):102004. pii:102004
  17. Prasad D, Khandeshi A, Sartin S, Jain R, Dahdaleh N, Lesniak M, Luo Y, Ahuja C  Will AI become our Co-PI?  NPJ Digit Med  2025 Jul 14;8(1):440. pii:440
  18. Fass OZ, Kristinsdottir K, Kaklamanos E, Soni P, Hudson K, Etemadi M, Pandolfino JE, Carlson DA  Improved Performance of an Updated Artificial Intelligence Model for Interpretation of Functional Lumen Imaging Probe Panometry Studies.  Neurogastroenterol Motil  2025 Jul 13;:e70120. doi:10.1111/nmo.70120
  19. Wang X, Li Y, Lin Z, Pla I, Gajjela R, Mattamana BB, Joshi M, Liu Y, Wang H, Zun AB  et al.  Microtopography-induced changes in cell nucleus morphology enhance bone regeneration by modulating the cellular secretome.  Nat Commun  2025 Jul 11;16(1):6444. pii:6444
  20. Rosenthal EA, Wei WQ, Luo Y, Namjou-Khales B, Schaid DJ, Esplin ED, Lape M, Kottyan L, Pacheco JA, Weng C  et al.  Phenome-wide association study identifies multiple traits associated with a polygenic risk score for colorectal cancer.  Hum Genomics  2025 Jul 09;19(1):77. pii:77
  21. Mithal LB, Becker ME, Ling-Hu T, Goo YA, Otero S, Kremer A, Pandey S, Lancki N, Li Y, Luo Y  et al.  Cord blood proteomics identifies biomarkers of early-onset neonatal sepsis.  JCI Insight  2025 Jul 08;10(13). pii:e193826
  22. Yaku H, Burkhoff D, Borlaug BA, Lala A, Butler J, Rich S, Shah SJ  Oral Levosimendan for the Treatment of Pulmonary Hypertension due to Heart Failure With Preserved Ejection Fraction: Rationale and Design of the LEVEL Trial.  J Card Fail  2025 Jul 07;. pii:S1071-9164(25)00293-3
  23. Hourmozdi J, Easton N, Benigeri S, Thomas JD, Narang A, Ouyang D, Duffy G, Upton R, Hawkes W, Akerman A  et al.  Evaluating the Performance and Potential Bias of Predictive Models for Detection of Transthyretin Cardiac Amyloidosis.  JACC Adv  2025 Jul 04;4(8):101901. pii:101901
  24. Yaku H, Eicher JC, Bergmann MW, Kister T, Pörner TC, Borlaug BA, Mohan RC, Price M, Komtebedde J, Shah SJ  Management of Flow Reversal in Patients With Atrial Shunts Implanted to Reduce Left Atrial Pressure.  JACC Case Rep  2025 Jul 02;30(17):103893. doi:10.1016/j.jaccas.2025.103893
  25. Naved BA, Ravishankar S, Colbert GE, Johnston A, Slott QM, Luo Y  LLM enabled classification of patient self-reported symptoms and needs in health systems across the USA.  NPJ Digit Med  2025 Jul 01;8(1):390. pii:390
  26. Pabon MA, Vardeny O, Vaduganathan M, Desai AS, Claggett BL, Kulac IJ, Jhund PS, Lam CSP, Senni M, Shah SJ  et al.  Finerenone in Heart Failure With Improved Ejection Fraction: The FINEARTS-HF Randomized Clinical Trial.  JAMA Cardiol  2025 Jul 01;10(7):740-745. doi:10.1001/jamacardio.2025.1101
  27. Barrett MA, Allen A, Vuong VT, Zhu D, Rainey AJ, McConnell WM, Kho AN, Salisbury A, French DD  Impact of an Artificial Intelligence and Machine Learning Enhanced Electronic Health Record System on Quality Measures in Nursing Homes: A Difference-in-Differences Analysis.  J Am Med Dir Assoc  2025 Jul;26(7):105680. doi:10.1016/j.jamda.2025.105680
  28. Dennis S, Tsukioki T, Kocherginsky M, Qi AK, DeHorn S, Gurley M, Wrubel E, Luo Y, Khan SA  Neoadjuvant Chemotherapy Response and Genetic Susceptibility in Recently Parous Women with Breast Cancer: A Retrospective Analysis.  Ann Surg Oncol  2025 Jul;32(7):4855-4864. doi:10.1245/s10434-025-17204-0
  29. Matsumoto S, Henderson AD, Jhund PS, Bauersachs J, Chioncel O, Claggett BL, Comin-Colet J, Desai AS, Filippatos G, Lam CSP  et al.  Finerenone and Atrial Fibrillation in Heart Failure: A Secondary Analysis of the FINEARTS-HF Randomized Clinical Trial.  JAMA Cardiol  2025 Jul 01;10(7):696-707. doi:10.1001/jamacardio.2025.0848
  30. Li M, Fass OZ, Carlson DA, Pitisuttithum P, Goudie E, Kristinsdottir K, Kaklamanos E, Etemadi M, Keswani RN, Ellison A  et al.  Endoscopic Prediction of Achalasia: Putting the CART Before the CARS.  Neurogastroenterol Motil  2025 Jul;37(7):e70024. pii:e70024
  31. Hosseini M, Holcombe AO, Kovacs M, Zwart H, Katz DS, Holmes K  Group authorship, an excellent opportunity laced with ethical, legal and technical challenges.  Account Res  2025 Jul;32(5):762-784. doi:10.1080/08989621.2024.2322557
  32. Herrold AA, Aaronson AL, Bhaumik D, Durazzo T, Livengood SL, Ramic A, Riordan P, Jordan N, Parrish T, Mallinson T  et al.  A Customized Neural Transcranial Magnetic Stimulation Target for Functional Disability Among Veterans With Co-Occurring Alcohol Use Disorder and Mild Traumatic Brain Injury: Protocol for a Pilot Randomized Controlled Trial.  JMIR Res Protoc  2025 Jun 23;14:e64909. pii:e64909
  33. Butt JH, Jhund PS, Henderson AD, Claggett BL, Chiang CE, Linssen GCM, Saldarriaga CI, Saraiva JFK, Sato N, Schou M  et al.  Finerenone According to Frailty in Heart Failure: A Prespecified Analysis of the FINEARTS-HF Randomized Clinical Trial.  JAMA Cardiol  2025 Jun 18;. pii:e251775
  34. Bisen JB, Sikora H, Aneja A, Shah SJ, Mirza RG  Retinal Imaging as a Window into Cardiovascular Health: Towards Harnessing Retinal Analytics for Precision Cardiovascular Medicine.  J Cardiovasc Dev Dis  2025 Jun 17;12(6). pii:230
  35. Li Y, Ding Y, Dennis S, Hutch MR, Zhou J, Zhou Y, Li Y, Pillai M, Ghotbaldini S, Garcia MA  et al.  SOAR elucidates biological insights and empowers drug discovery through spatial transcriptomics.  Sci Adv  2025 Jun 13;11(24):eadt7450. doi:10.1126/sciadv.adt7450
  36. Dennis SR, Tsukioki T, Cottone G, Zhou W, Ganz PA, Sehl ME, Luo Y, Khan SA, Clare S  DNA methylation patterns in breast cancer, paired benign tissue from ipsilateral and contralateral breast, and healthy controls.  Breast Cancer Res  2025 Jun 11;27(1):103. pii:103
  37. Doiron JE, Elbatreek MH, Xia H, Yu X, Gehred ND, Gromova T, Chen J, Driver IH, Muraoka N, Jensen M  et al.  Hydrogen Sulfide Deficiency and Therapeutic Targeting in Cardiometabolic HFpEF: Evidence for Synergistic Benefit With GLP-1/Glucagon Agonism.  JACC Basic Transl Sci  2025 Jun 04;:101297. doi:10.1016/j.jacbts.2025.04.011
  38. Huang J, Wittbrodt MT, Teague CN, Karl E, Galal G, Thompson M, Chapa A, Chiu ML, Herynk B, Linchangco R  et al.  Efficiency and Quality of Generative AI-Assisted Radiograph Reporting.  JAMA Netw Open  2025 Jun 02;8(6):e2513921. pii:e2513921
  39. Rambarat P, DeVore AD, Bhatt AS, Allen LA, McIlvennan CK, Cotter G, Mukhopadhyay A, Ahmad T, Ahmad FS, Psotka MA  Failure to Launch: Insights From Randomized Trials on Implementation Strategies for Guideline-Directed Therapies for Heart Failure.  JACC Heart Fail  2025 Jun;13(6):887-900. doi:10.1016/j.jchf.2025.02.023
  40. Sehgal S, Starren J, Cattin K, Bilaver L, Gururaj A, Togias A, Gupta RS  Common data elements for food allergy clinical trials: an overview.  Curr Opin Allergy Clin Immunol  2025 Jun 01;25(3):194-198. doi:10.1097/ACI.0000000000001075
  41. Brokamp E, Miller-Fleming T, Scalici A, Hooker G, Hamid R, Velez Edwards D, Chung WK, Luo Y, Kiryluk K, Limidi NA  et al.  Systematic method for classifying multiple congenital anomaly cases in electronic health records.  Genet Med  2025 Jun;27(6):101415. doi:10.1016/j.gim.2025.101415
  42. Sandlow S, Carbunaru S, Sun Z, Ofori B, Liu Y, Li E, Hollowell CMP, Vidal P, Perry KT, Patel HD  et al.  Negative Predictive Value of a Prostate MRI in Black Men: Implications for Biopsy Decision-Making.  J Urol  2025 Jun;213(6):713-721. doi:10.1097/JU.0000000000004498
  43. Armoundas AA, Ahmad FS, Attia ZI, Doudesis D, Khera R, Kyriakoulis KG, Stergiou GS, Tang WHW  Controversy in Hypertension: Pro-Side of the Argument Using Artificial Intelligence for Hypertension Diagnosis and Management.  Hypertension  2025 Jun;82(6):929-944. doi:10.1161/HYPERTENSIONAHA.124.22349
  44. Pandey A, Lewis GD, Borlaug BA, Shah SJ, Sauer AJ, Litwin S, Sharma K, Jorkasky DK, Tarka EA, Khan SM  et al.  Novel Controlled Metabolic Accelerator for Obesity-Related HFpEF: The HuMAIN-HFpEF Randomized Clinical Trial.  JAMA Cardiol  2025 Jun 01;10(6):609-616. doi:10.1001/jamacardio.2025.0103
  45. Tavolinejad H, Boczar KE, Spronck B, Maynard H, Bertoni AG, Shah SJ, Chirinos JA  Determinants of Cardio-Ankle Vascular Index and Heart-Thigh β Index in the MESA.  Hypertension  2025 Jun;82(6):1081-1094. doi:10.1161/HYPERTENSIONAHA.124.23970
  46. McDowell K, Docherty KF, Campbell RT, Henderson AD, Jhund PS, Claggett BL, Desai AS, Lay-Flurrie J, Hofmeister L, Scalise A  et al.  Finerenone for Heart Failure and Risk Estimated by the PREDICT-HFpEF Model: A Secondary Analysis of FINEARTS-HF.  JAMA Cardiol  2025 Jun 01;10(6):535-544. doi:10.1001/jamacardio.2025.0025
  47. Ambrosy AP, Sauer AJ, Patel S, Windsor SL, Borlaug BA, Husain M, Inzucchi SE, Kitzman DW, McGuire DK, Shah SJ  et al.  Baseline kidney function and the effects of dapagliflozin on health status in heart failure in DEFINE-HF and PRESERVED-HF.  ESC Heart Fail  2025 Jun;12(3):1676-1681. doi:10.1002/ehf2.15184
  48. Michelson KN, Fishman AC, Feinberg EC, Ross S, Wald HS, Auerbach C, Roth S  Antisemitism in American Healthcare: A Survey Study of Reported Experiences.  J Gen Intern Med  2025 Jun;40(8):1940-1943. doi:10.1007/s11606-024-09159-x
  49. Hasjim BJ, Mohammadi M, Balbale SN, Paukner M, Banea T, Shi H, Furmanchuk A, VanWagner LB, Zhao L, Duarte-Rojo A  et al.  High Hospitalization Rates and Risk Factors Among Frail Patients With Cirrhosis: A 10-year Population-based Cohort Study.  Clin Gastroenterol Hepatol  2025 Jun;23(7):1152-1163. doi:10.1016/j.cgh.2024.08.044
  50. Goldstein JA, Nateghi R, Cooper LAD  Machine Learning Assessment of Gestational Age in Accelerated Maturation, Delayed Maturation, Villous Edema, Chorangiosis, and Intrauterine Fetal Demise.  Arch Pathol Lab Med  2025 Jun 01;149(6):503-510. doi:10.5858/arpa.2024-0274-OA

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