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Northwestern University Feinberg School of Medicine
Institute for Artificial Intelligence in Medicine

Publications

Browse the list below to see the latest scientific publications stemming from our institute faculty’s work. To view publications of specific AI faculty, please visit Membership and select a profile link.

  1. Sehgal S, Starren J, Cattin K, Bilaver L, Gururaj A, Togias A, Gupta RS  Common data elements for food allergy clinical trials: an overview.  Curr Opin Allergy Clin Immunol  2025 Jun 01;25(3):194-198. doi:10.1097/ACI.0000000000001075
  2. Ambrosy AP, Sauer AJ, Patel S, Windsor SL, Borlaug BA, Husain M, Inzucchi SE, Kitzman DW, McGuire DK, Shah SJ  et al.  Baseline kidney function and the effects of dapagliflozin on health status in heart failure in DEFINE-HF and PRESERVED-HF.  ESC Heart Fail  2025 Jun;12(3):1676-1681. doi:10.1002/ehf2.15184
  3. Wang H, Schwirtlich T, Houskamp EJ, Hutch MR, Murphy JX, do Nascimento JS, Zini A, Brancaleoni L, Giacomozzi S, Luo Y  et al.  Automated Detection of Black Hole Sign for Intracerebral Hemorrhage Patients Using Self-Supervised Learning.  AJNR Am J Neuroradiol  2025 May 07;. pii:ajnr.A8826
  4. Pabon MA, Filippatos G, Claggett BL, Miao MZ, Desai AS, Jhund PS, Henderson A, Brinker M, Schloemer P, Hofmeister L  et al.  Finerenone Reduces New-Onset Atrial Fibrillation Across the Spectrum of Cardio-Kidney-Metabolic Syndrome: The FINE-HEART Pooled Analysis.  J Am Coll Cardiol  2025 May 06;85(17):1649-1660. doi:10.1016/j.jacc.2025.03.429
  5. Braumann S, Macherey-Meyer S, Polzin A, Costard-Jäckle A, Morbach C, Haring B, Lapp H, Ten Cate V, Gieswinkel A, Weliwitage J  et al.  MYSTERY-HF: Myeloperoxidase Inhibition in Patients With Heart Failure and Reduced Ejection Fraction: A Phase II Randomized Controlled Trial.  Circulation  2025 May 06;151(18):1372-1374. doi:10.1161/CIRCULATIONAHA.125.074085
  6. Smith JD, Carroll AJ, Tedla YG, Sanuade OA, Merle JL, Heinrich J, Bannon J, Abramsohn EM, Ahmad FS, Lazar D  et al.  Community intervention to reduce cardiovascular disease in Chicago (CIRCL-Chicago): protocol for a type 3 hybrid effectiveness-implementation study using a parallel cluster-randomized trial design.  Implement Sci  2025 May 05;20(1):19. pii:19
  7. Philbin SE, Gleason LP, Persell SD, Walter E, Petito LC, Tibrewala A, Yancy CW, Beidas RS, Wilcox JE, Mutharasan RK  et al.  Barriers and Facilitators to Heart Failure Guideline-Directed Medical Therapy in an Integrated Health System and Federally Qualified Health Centers: A Thematic Qualitative Analysis.  J Gen Intern Med  2025 May 05;. doi:10.1007/s11606-025-09515-5
  8. Culler K, Zelnick LR, Mehta RC, de Sosa GR, Kansal M, Rao PS, Bhat Z, Taliercio J, Horwitz E, Chen J  et al.  The ICAM1 p.K56M variant and risk of heart failure in chronic kidney disease: the Chronic Renal Insufficiency Cohort study.  Heart  2025 May 02;111(10):441-444. doi:10.1136/heartjnl-2024-325205
  9. Berhane H, Maroun A, Dushfunian D, Baraboo J, Martinez G, Jacobson T, Bagci U, Allen BD, Markl M  Anatomy-derived 3D Aortic Hemodynamics Using Fluid Physics-informed Deep Learning.  Radiology  2025 May;315(2):e240714. doi:10.1148/radiol.240714
  10. Ostrominski JW, Claggett BL, Miao ZM, Filippatos G, Desai AS, Jhund PS, Henderson A, Brinker M, Schloemer P, Viswanathan P  et al.  Efficacy and Safety of Finerenone in Type 2 Diabetes: A Pooled Analysis of Trials of Heart Failure and Chronic Kidney Disease.  Diabetes Care  2025 May 01;48(5):745-755. doi:10.2337/dc24-1873
  11. Friedewald SM, Sieniek M, Jansen S, Mahvar F, Kohlberger T, Schacht D, Bhole S, Gupta D, Prabhakara S, McKinney SM  et al.  Triaging mammography with artificial intelligence: an implementation study.  Breast Cancer Res Treat  2025 May;211(1):1-10. doi:10.1007/s10549-025-07616-7
  12. Li EV, Ren Y, Griffin J, Han J, Yamashita R, Mitani A, Zhou R, Huang HC, Yang X, Feng FY  et al.  An Artificial Intelligence-Digital Pathology Algorithm Predicts Survival After Radical Prostatectomy From the Prostate, Lung, Colorectal, and Ovarian Cancer Trial.  J Urol  2025 May;213(5):600-608. doi:10.1097/JU.0000000000004435
  13. Stefanopoulos L, Kim BW, Sheppard J, Azcona EA, Vike NL, Bari S, Lalvani S, Woodward S, Maglaveras N, Block M  et al.  Discrete, recurrent, and scalable patterns in non-operant judgement underlie affective picture ratings.  Cogn Process  2025 May;26(2):257-281. doi:10.1007/s10339-024-01250-9
  14. Butt JH, Jhund PS, Henderson AD, Claggett BL, Desai AS, Lam CSP, Mueller K, Scheerer MF, Viswanathan P, Senni M  et al.  Finerenone, chronic obstructive pulmonary disease, and heart failure with mildly reduced or preserved ejection fraction: A prespecified analysis of the FINEARTS-HF trial.  Eur J Heart Fail  2025 Apr 13;. doi:10.1002/ejhf.3661
  15. Butt JH, Jhund PS, Henderson AD, Claggett BL, Desai AS, Lam CSP, Brinker M, Schloemer P, Viswanathan P, Lage A  et al.  Finerenone, glycaemic status, and heart failure with mildly reduced or preserved ejection fraction: A prespecified analysis of the FINEARTS-HF trial.  Eur J Heart Fail  2025 Apr 10;. doi:10.1002/ejhf.3649
  16. Kim M, Rogers L, Batio S, Benavente JY, Bonham M, Zheng P, Lovett RM, Bailey SC, Kwasny MJ, Ladner DP  et al.  Trajectories of sleep disturbance and self-management of chronic conditions during COVID-19 among middle-aged and older adults.  Sci Rep  2025 Apr 10;15(1):12324. pii:12324
  17. Choi J, Gordon A, Eresen A, Zhang Z, Borhani A, Bagci U, Lewandowski R, Kim DH  Current applications of radiomics in the assessment of tumor microenvironment of hepatocellular carcinoma.  Abdom Radiol (NY)  2025 Apr 10;. doi:10.1007/s00261-025-04916-w
  18. Luo Y, Assassi S, Mayes MD, Frech TM, Steen VD, Richardson C, Chung L, Sandorfi N, VanBuren JM, Harding M  et al.  Use of Nintedanib for the Treatment of Systemic Sclerosis-associated Interstitial Lung Disease at Expert Scleroderma Centers in the United States.  Ann Am Thorac Soc  2025 Apr 10;. doi:10.1513/AnnalsATS.202410-1045RL
  19. Masri A, Aras M, Grogan M, Jacoby D, Maurer MS, Shah SJ, Witteles R, Wong PW, Ji AX, Du J  et al.  Acoramidis for Transthyretin Amyloid Cardiomyopathy: Open-Label Extension Study Long-Term Follow-Up.  J Card Fail  2025 Apr 09;. pii:S1071-9164(25)00162-9
  20. Dennis S, Tsukioki T, Kocherginsky M, Qi AK, DeHorn S, Gurley M, Wrubel E, Luo Y, Khan SA  Neoadjuvant Chemotherapy Response and Genetic Susceptibility in Recently Parous Women with Breast Cancer: A Retrospective Analysis.  Ann Surg Oncol  2025 Apr 09;. doi:10.1245/s10434-025-17204-0
  21. Ostrominski JW, Højbjerg Lassen MC, Claggett BL, Miao ZM, Inzucchi SE, Docherty KF, Desai AS, Jhund PS, Køber L, Ponikowski P  et al.  Sodium-glucose co-transporter 2 inhibitors and new-onset diabetes in cardiovascular or kidney disease.  Eur Heart J  2025 Apr 07;46(14):1321-1331. doi:10.1093/eurheartj/ehae780
  22. Wagholikar KB, Pacheco JA, Gordon AS, Khan A, Khales BN, Benoit B, Kerman BJ, Weng C, Ta C, Prows CA  et al.  Current Limitations of Electronic Health Record Systems in Supporting Pragmatic Clinical Trials: Insights from the eMERGE Consortium.  medRxiv  2025 Apr 03;. pii:2025.04.01.25325049
  23. Ostrominski JW, Vaduganathan M, Claggett BL, Desai AS, Jhund PS, Lam CSP, Senni M, Shah SJ, Voors AA, Zannad F  et al.  Finerenone and New York Heart Association Functional Class in Heart Failure: The FINEARTS-HF Trial.  JACC Heart Fail  2025 Apr 02;. pii:S2213-1779(25)00242-2
  24. Ostrominski JW, Mc Causland FR, Claggett BL, Desai AS, Jhund PS, Lam CSP, Senni M, Shah SJ, Voors AA, Zannad F  et al.  Finerenone Across the Spectrum of Kidney Risk in Heart Failure: The FINEARTS-HF Trial.  JACC Heart Fail  2025 Apr 02;. pii:S2213-1779(25)00241-0
  25. Day S, Shah SJ, Onyeama UF, Fidelak L, Nwaozuru U, Rennie S, Babatunde AO, Tang W, Rousseau E, Obiezu-Umeh C  et al.  Consensus on Adolescent and Young Adult HIV Research Consent in Low- and Middle-Income Countries.  JAMA Netw Open  2025 Apr 01;8(4):e257879. doi:10.1001/jamanetworkopen.2025.7879
  26. Friedman E, Michelson KN, Sehgal S, Steans R, Hosseini M, Baumann MJ, Venables AK, Walunas TL, Starren J  Implications for Precision Accelerated Clinically Embedded Research (PACER): A novel technology-enabled approach to conducting minimal-risk research in outpatient community healthcare settings.  PLoS One  2025;20(4):e0318533. pii:e0318533
  27. Rojas JC, Lyons PG, Chhikara K, Chaudhari V, Bhavani SV, Nour M, Buell KG, Smith KD, Gao CA, Amagai S  et al.  Correction: A common longitudinal intensive care unit data format (CLIF) for critical illness research.  Intensive Care Med  2025 Apr;51(4):836-839. doi:10.1007/s00134-025-07869-2
  28. Yu JK, Gauen AM, Zmora R, Petito LC, Kho AN, Smith SM, Allen NB  Patient Predictors of Combination Therapy as Initial Hypertension Treatment: The AOURP (All of Us Research Program) Registry.  J Am Heart Assoc  2025 Apr;14(7):e037626. doi:10.1161/JAHA.124.037626
  29. Inciardi RM, Lu H, Claggett BL, Desai AS, Jhund PS, Lam CSP, Kosiborod MN, Inzucchi SE, Martinez FA, de Boer RA  et al.  Severe Heart Failure and Treatment With Dapagliflozin Across the Ejection Fraction Spectrum: DAPA-HF and DELIVER.  JACC Heart Fail  2025 Apr;13(4):618-627. doi:10.1016/j.jchf.2024.11.023
  30. Sorimachi H, Obokata M, Omote K, Reddy YNV, Burkhoff D, Shah SJ, Borlaug BA  Racial Differences of Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction.  J Card Fail  2025 Apr;31(4):624-634. doi:10.1016/j.cardfail.2024.08.042
  31. Kane C, Trochim W, Bar H, Vaught A, Baker H, Khan M, Wagner R, Holmes K, Herzog K, Doyle JM  Navigating the road ahead: using concept mapping to assess Clinical and Translational Science Award (CTSA) program goals.  Front Public Health  2025;13:1562191. pii:1562191
  32. Zhang B, Wu Q, Jhaveri R, Zhou T, Becich MJ, Bisyuk Y, Blanceró F, Chrischilles EA, Chuang CH, Cowell LG  et al.  Reinfection with SARS-CoV-2 in the Omicron Era is Associated with Increased Risk of Post-Acute Sequelae of SARS-CoV-2 Infection: A RECOVER-EHR Cohort Study.  medRxiv  2025 Mar 30;. pii:2025.03.28.25324858
  33. Matsumoto S, Henderson AD, Jhund PS, Bauersachs J, Chioncel O, Claggett BL, Comin-Colet J, Desai AS, Filippatos G, Lam CSP  et al.  Finerenone and Atrial Fibrillation in Heart Failure: A Secondary Analysis of the FINEARTS-HF Randomized Clinical Trial.  JAMA Cardiol  2025 Mar 29;. pii:e250848
  34. Wang A, French D, Black B, Kho AN  Cohort study examining social determinants of health and their association with mortality among hospitalised adults in New York and California.  BMJ Public Health  2025 Jan;3(1):e001266. pii:e001266
  35. Eduardo MB, Cottone G, McCloskey CW, Liu S, Palma FR, Zappia MP, Islam ABMMK, Gao P, Setya J, Dennis S  et al.  A metabolic shift to the serine pathway induced by lipids fosters epigenetic reprogramming in nontransformed breast cells.  Sci Adv  2025 Mar 21;11(12):eads9182. pii:eads9182
  36. Brokamp E, Miller-Fleming T, Scalici A, Hooker G, Hamid R, Velez Edwards D, Chung W, Luo Y, Kiryluk K, Limidi NA  et al.  Systematic Method for Classifying Multiple Congenital Anomaly Cases in Electronic Health Records.  Genet Med  2025 Mar 18;:101415. doi:10.1016/j.gim.2025.101415
  37. Sandlow S, Carbunaru S, Sun Z, Ofori B, Liu Y, Li E, Hollowell CMP, Vidal P, Perry KT, Patel HD  et al.  Negative Predictive Value of a Prostate MRI in Black Men: Implications for Biopsy Decision-Making.  J Urol  2025 Mar 17;:101097JU0000000000004498. doi:10.1097/JU.0000000000004498
  38. Li M, Fass OZ, Carlson DA, Pitisuttithum P, Goudie E, Kristinsdottir K, Kaklamanos E, Etemadi M, Keswani RN, Ellison A  et al.  Endoscopic Prediction of Achalasia: Putting the CART Before the CARS.  Neurogastroenterol Motil  2025 Mar 17;:e70024. doi:10.1111/nmo.70024
  39. Armoundas AA, Ahmad FS, Attia ZI, Doudesis D, Khera R, Kyriakoulis KG, Stergiou GS, Tang WHW  Controversy in Hypertension: Pro-Side of the Argument Using Artificial Intelligence for Hypertension Diagnosis and Management.  Hypertension  2025 Mar 17;. doi:10.1161/HYPERTENSIONAHA.124.22349
  40. Wang Q, Wang J, Mathur R, Youngblood MW, Jin Q, Hou Y, Stasiak LA, Luan Y, Zhao H, Hilz S  et al.  Spatial 3D genome organization reveals intratumor heterogeneity in primary glioblastoma samples.  Sci Adv  2025 Mar 14;11(11):eadn2830. pii:eadn2830
  41. Amagai S, Chaudhari V, Chhikara K, Ingraham NE, Hochberg CH, Barker AK, Mao C, Ortiz AC, Weissman GE, Schmid BE  et al.  The Epidemiology of Intensive Care Unit Readmissions Across Ten Health Systems.  medRxiv  2025 Mar 13;. pii:2025.03.10.25323672
  42. Knapp AA, Cohen K, Kruzan KP, Kornfield R, Herrera M, Pederson AB, Lee S, Macapagal K, Roulston CA, Clarke K  et al.  Teen Perspectives on Integrating Digital Mental Health Programs for Teens Into Public Libraries ("I Was Always at the Library"): Qualitative Interview Study.  JMIR Form Res  2025 Mar 13;9:e67454. pii:e67454
  43. Pandey A, Lewis GD, Borlaug BA, Shah SJ, Sauer AJ, Litwin S, Sharma K, Jorkasky DK, Tarka EA, Khan SM  et al.  Novel Controlled Metabolic Accelerator for Obesity-Related HFpEF: The HuMAIN-HFpEF Randomized Clinical Trial.  JAMA Cardiol  2025 Mar 12;. pii:e250103
  44. Filipp M, Ge ZD, DeBerge M, Lantz C, Glinton K, Gao P, Smolgovsky S, Dai J, Zhao YY, Yvan-Charvet L  et al.  Myeloid Fatty Acid Metabolism Activates Neighboring Hematopoietic Stem Cells to Promote Heart Failure With Preserved Ejection Fraction.  Circulation  2025 Mar 12;. doi:10.1161/CIRCULATIONAHA.124.070248
  45. Tavolinejad H, Boczar KE, Spronck B, Maynard H, Bertoni AG, Shah SJ, Chirinos JA  Determinants of Cardio-Ankle Vascular Index and Heart-Thigh β Index in a US Cohort: The MESA.  Hypertension  2025 Mar 07;. doi:10.1161/HYPERTENSIONAHA.124.23970
  46. McDowell K, Docherty KF, Campbell RT, Henderson AD, Jhund PS, Claggett BL, Desai AS, Lay-Flurrie J, Hofmeister L, Scalise A  et al.  Finerenone for Heart Failure and Risk Estimated by the PREDICT-HFpEF Model: A Secondary Analysis of FINEARTS-HF.  JAMA Cardiol  2025 Mar 05;. pii:e250025
  47. Eisinger-Mathason TSK, Leshin J, Lahoti V, Fridsma DB, Mucaj V, Kho AN  Data linkage multiplies research insights across diverse healthcare sectors.  Commun Med (Lond)  2025 Mar 04;5(1):58. pii:58
  48. Kanwar K, Ramachandran R, Stein JD, Andrews CA, Chaudhury AS, Ige M, Zhou X, Marwah S, Li Y, Evans CT  et al.  The Association of Social Determinants of Health on Monitoring for Disease Progression Among Patients With Primary Open-Angle Glaucoma.  Transl Vis Sci Technol  2025 Mar 03;14(3):15. pii:15
  49. Rojas JC, Lyons PG, Chhikara K, Chaudhari V, Bhavani SV, Nour M, Buell KG, Smith KD, Gao CA, Amagai S  et al.  A common longitudinal intensive care unit data format (CLIF) for critical illness research.  Intensive Care Med  2025 Mar;51(3):556-569. doi:10.1007/s00134-025-07848-7
  50. Shah SJ, Bonderman D, Borlaug BA, Cleland JGF, Lack G, Lu W, Voors AA, Zannad F, Gladwin MT  Macitentan for Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Pulmonary Vascular Disease: Results of the SERENADE Randomized Clinical Trial and Open-Label Extension Study.  Circ Heart Fail  2025 Mar;18(3):e011381. doi:10.1161/CIRCHEARTFAILURE.123.011381

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