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Northwestern University Feinberg School of Medicine
Institute for Artificial Intelligence in Medicine

Publications

Browse the list below to see the latest scientific publications stemming from our institute faculty’s work. To view publications of specific AI faculty, please visit Membership and select a profile link.

  1. Ostrominski JW, Claggett BL, Miao ZM, Filippatos G, Desai AS, Jhund PS, Henderson A, Brinker M, Schloemer P, Viswanathan P  et al.  Efficacy and Safety of Finerenone in Type 2 Diabetes: A Pooled Analysis of Trials of Heart Failure and Chronic Kidney Disease.  Diabetes Care  2025 May 01;48(5):745-755. doi:10.2337/dc24-1873
  2. Friedewald SM, Sieniek M, Jansen S, Mahvar F, Kohlberger T, Schacht D, Bhole S, Gupta D, Prabhakara S, McKinney SM  et al.  Triaging mammography with artificial intelligence: an implementation study.  Breast Cancer Res Treat  2025 May;211(1):1-10. doi:10.1007/s10549-025-07616-7
  3. Li EV, Ren Y, Griffin J, Han J, Yamashita R, Mitani A, Zhou R, Huang HC, Yang X, Feng FY  et al.  An Artificial Intelligence-Digital Pathology Algorithm Predicts Survival After Radical Prostatectomy From the Prostate, Lung, Colorectal, and Ovarian Cancer Trial.  J Urol  2025 May;213(5):600-608. doi:10.1097/JU.0000000000004435
  4. Butt JH, Jhund PS, Henderson AD, Claggett BL, Desai AS, Lam CSP, Mueller K, Scheerer MF, Viswanathan P, Senni M  et al.  Finerenone, chronic obstructive pulmonary disease, and heart failure with mildly reduced or preserved ejection fraction: A prespecified analysis of the FINEARTS-HF trial.  Eur J Heart Fail  2025 Apr 13;. doi:10.1002/ejhf.3661
  5. Sehgal S, Starren J, Cattin K, Bilaver L, Gururaj A, Togias A, Gupta RS  Common data elements for food allergy clinical trials: an overview.  Curr Opin Allergy Clin Immunol  2025 Apr 10;. doi:10.1097/ACI.0000000000001075
  6. Butt JH, Jhund PS, Henderson AD, Claggett BL, Desai AS, Lam CSP, Brinker M, Schloemer P, Viswanathan P, Lage A  et al.  Finerenone, glycaemic status, and heart failure with mildly reduced or preserved ejection fraction: A prespecified analysis of the FINEARTS-HF trial.  Eur J Heart Fail  2025 Apr 10;. doi:10.1002/ejhf.3649
  7. Kim M, Rogers L, Batio S, Benavente JY, Bonham M, Zheng P, Lovett RM, Bailey SC, Kwasny MJ, Ladner DP  et al.  Trajectories of sleep disturbance and self-management of chronic conditions during COVID-19 among middle-aged and older adults.  Sci Rep  2025 Apr 10;15(1):12324. pii:12324
  8. Choi J, Gordon A, Eresen A, Zhang Z, Borhani A, Bagci U, Lewandowski R, Kim DH  Current applications of radiomics in the assessment of tumor microenvironment of hepatocellular carcinoma.  Abdom Radiol (NY)  2025 Apr 10;. doi:10.1007/s00261-025-04916-w
  9. Luo Y, Assassi S, Mayes MD, Frech TM, Steen VD, Richardson C, Chung L, Sandorfi N, VanBuren JM, Harding M  et al.  Use of Nintedanib for the Treatment of Systemic Sclerosis-associated Interstitial Lung Disease at Expert Scleroderma Centers in the United States.  Ann Am Thorac Soc  2025 Apr 10;. doi:10.1513/AnnalsATS.202410-1045RL
  10. Masri A, Aras M, Grogan M, Jacoby D, Maurer MS, Shah SJ, Witteles R, Wong PW, Ji AX, Du J  et al.  Acoramidis for Transthyretin Amyloid Cardiomyopathy: Open-Label Extension Study Long-Term Follow-Up.  J Card Fail  2025 Apr 09;. pii:S1071-9164(25)00162-9
  11. Dennis S, Tsukioki T, Kocherginsky M, Qi AK, DeHorn S, Gurley M, Wrubel E, Luo Y, Khan SA  Neoadjuvant Chemotherapy Response and Genetic Susceptibility in Recently Parous Women with Breast Cancer: A Retrospective Analysis.  Ann Surg Oncol  2025 Apr 09;. doi:10.1245/s10434-025-17204-0
  12. Ostrominski JW, Højbjerg Lassen MC, Claggett BL, Miao ZM, Inzucchi SE, Docherty KF, Desai AS, Jhund PS, Køber L, Ponikowski P  et al.  Sodium-glucose co-transporter 2 inhibitors and new-onset diabetes in cardiovascular or kidney disease.  Eur Heart J  2025 Apr 07;46(14):1321-1331. doi:10.1093/eurheartj/ehae780
  13. Wagholikar KB, Pacheco JA, Gordon AS, Khan A, Khales BN, Benoit B, Kerman BJ, Weng C, Ta C, Prows CA  et al.  Current Limitations of Electronic Health Record Systems in Supporting Pragmatic Clinical Trials: Insights from the eMERGE Consortium.  medRxiv  2025 Apr 03;. pii:2025.04.01.25325049
  14. Ostrominski JW, Vaduganathan M, Claggett BL, Desai AS, Jhund PS, Lam CSP, Senni M, Shah SJ, Voors AA, Zannad F  et al.  Finerenone and New York Heart Association Functional Class in Heart Failure: The FINEARTS-HF Trial.  JACC Heart Fail  2025 Apr 02;. pii:S2213-1779(25)00242-2
  15. Ostrominski JW, Mc Causland FR, Claggett BL, Desai AS, Jhund PS, Lam CSP, Senni M, Shah SJ, Voors AA, Zannad F  et al.  Finerenone Across the Spectrum of Kidney Risk in Heart Failure: The FINEARTS-HF Trial.  JACC Heart Fail  2025 Apr 02;. pii:S2213-1779(25)00241-0
  16. Friedman E, Michelson KN, Sehgal S, Steans R, Hosseini M, Baumann MJ, Venables AK, Walunas TL, Starren J  Implications for Precision Accelerated Clinically Embedded Research (PACER): A novel technology-enabled approach to conducting minimal-risk research in outpatient community healthcare settings.  PLoS One  2025;20(4):e0318533. pii:e0318533
  17. Yu JK, Gauen AM, Zmora R, Petito LC, Kho AN, Smith SM, Allen NB  Patient Predictors of Combination Therapy as Initial Hypertension Treatment: The AOURP (All of Us Research Program) Registry.  J Am Heart Assoc  2025 Apr;14(7):e037626. doi:10.1161/JAHA.124.037626
  18. Inciardi RM, Lu H, Claggett BL, Desai AS, Jhund PS, Lam CSP, Kosiborod MN, Inzucchi SE, Martinez FA, de Boer RA  et al.  Severe Heart Failure and Treatment With Dapagliflozin Across the Ejection Fraction Spectrum: DAPA-HF and DELIVER.  JACC Heart Fail  2025 Apr;13(4):618-627. doi:10.1016/j.jchf.2024.11.023
  19. Sorimachi H, Obokata M, Omote K, Reddy YNV, Burkhoff D, Shah SJ, Borlaug BA  Racial Differences of Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction.  J Card Fail  2025 Apr;31(4):624-634. doi:10.1016/j.cardfail.2024.08.042
  20. Kane C, Trochim W, Bar H, Vaught A, Baker H, Khan M, Wagner R, Holmes K, Herzog K, Doyle JM  Navigating the road ahead: using concept mapping to assess Clinical and Translational Science Award (CTSA) program goals.  Front Public Health  2025;13:1562191. pii:1562191
  21. Rojas JC, Lyons PG, Chhikara K, Chaudhari V, Bhavani SV, Nour M, Buell KG, Smith KD, Gao CA, Amagai S  et al.  Correction: A common longitudinal intensive care unit data format (CLIF) for critical illness research.  Intensive Care Med  2025 Mar 31;. doi:10.1007/s00134-025-07869-2
  22. Zhang B, Wu Q, Jhaveri R, Zhou T, Becich MJ, Bisyuk Y, Blanceró F, Chrischilles EA, Chuang CH, Cowell LG  et al.  Reinfection with SARS-CoV-2 in the Omicron Era is Associated with Increased Risk of Post-Acute Sequelae of SARS-CoV-2 Infection: A RECOVER-EHR Cohort Study.  medRxiv  2025 Mar 30;. pii:2025.03.28.25324858
  23. Matsumoto S, Henderson AD, Jhund PS, Bauersachs J, Chioncel O, Claggett BL, Comin-Colet J, Desai AS, Filippatos G, Lam CSP  et al.  Finerenone and Atrial Fibrillation in Heart Failure: A Secondary Analysis of the FINEARTS-HF Randomized Clinical Trial.  JAMA Cardiol  2025 Mar 29;. pii:e250848
  24. Wang A, French D, Black B, Kho AN  Cohort study examining social determinants of health and their association with mortality among hospitalised adults in New York and California.  BMJ Public Health  2025 Jan;3(1):e001266. pii:e001266
  25. Eduardo MB, Cottone G, McCloskey CW, Liu S, Palma FR, Zappia MP, Islam ABMMK, Gao P, Setya J, Dennis S  et al.  A metabolic shift to the serine pathway induced by lipids fosters epigenetic reprogramming in nontransformed breast cells.  Sci Adv  2025 Mar 21;11(12):eads9182. pii:eads9182
  26. Brokamp E, Miller-Fleming T, Scalici A, Hooker G, Hamid R, Velez Edwards D, Chung W, Luo Y, Kiryluk K, Limidi NA  et al.  Systematic Method for Classifying Multiple Congenital Anomaly Cases in Electronic Health Records.  Genet Med  2025 Mar 18;:101415. doi:10.1016/j.gim.2025.101415
  27. Sandlow S, Carbunaru S, Sun Z, Ofori B, Liu Y, Li E, Hollowell CMP, Vidal P, Perry KT, Patel HD  et al.  Negative Predictive Value of a Prostate MRI in Black Men: Implications for Biopsy Decision-Making.  J Urol  2025 Mar 17;:101097JU0000000000004498. doi:10.1097/JU.0000000000004498
  28. Li M, Fass OZ, Carlson DA, Pitisuttithum P, Goudie E, Kristinsdottir K, Kaklamanos E, Etemadi M, Keswani RN, Ellison A  et al.  Endoscopic Prediction of Achalasia: Putting the CART Before the CARS.  Neurogastroenterol Motil  2025 Mar 17;:e70024. doi:10.1111/nmo.70024
  29. Armoundas AA, Ahmad FS, Attia ZI, Doudesis D, Khera R, Kyriakoulis KG, Stergiou GS, Tang WHW  Controversy in Hypertension: Pro-Side of the Argument Using Artificial Intelligence for Hypertension Diagnosis and Management.  Hypertension  2025 Mar 17;. doi:10.1161/HYPERTENSIONAHA.124.22349
  30. Wang Q, Wang J, Mathur R, Youngblood MW, Jin Q, Hou Y, Stasiak LA, Luan Y, Zhao H, Hilz S  et al.  Spatial 3D genome organization reveals intratumor heterogeneity in primary glioblastoma samples.  Sci Adv  2025 Mar 14;11(11):eadn2830. pii:eadn2830
  31. Amagai S, Chaudhari V, Chhikara K, Ingraham NE, Hochberg CH, Barker AK, Mao C, Ortiz AC, Weissman GE, Schmid BE  et al.  The Epidemiology of Intensive Care Unit Readmissions Across Ten Health Systems.  medRxiv  2025 Mar 13;. pii:2025.03.10.25323672
  32. Knapp AA, Cohen K, Kruzan KP, Kornfield R, Herrera M, Pederson AB, Lee S, Macapagal K, Roulston CA, Clarke K  et al.  Teen Perspectives on Integrating Digital Mental Health Programs for Teens Into Public Libraries ("I Was Always at the Library"): Qualitative Interview Study.  JMIR Form Res  2025 Mar 13;9:e67454. pii:e67454
  33. Pandey A, Lewis GD, Borlaug BA, Shah SJ, Sauer AJ, Litwin S, Sharma K, Jorkasky DK, Tarka EA, Khan SM  et al.  Novel Controlled Metabolic Accelerator for Obesity-Related HFpEF: The HuMAIN-HFpEF Randomized Clinical Trial.  JAMA Cardiol  2025 Mar 12;. pii:e250103
  34. Filipp M, Ge ZD, DeBerge M, Lantz C, Glinton K, Gao P, Smolgovsky S, Dai J, Zhao YY, Yvan-Charvet L  et al.  Myeloid Fatty Acid Metabolism Activates Neighboring Hematopoietic Stem Cells to Promote Heart Failure With Preserved Ejection Fraction.  Circulation  2025 Mar 12;. doi:10.1161/CIRCULATIONAHA.124.070248
  35. Tavolinejad H, Boczar KE, Spronck B, Maynard H, Bertoni AG, Shah SJ, Chirinos JA  Determinants of Cardio-Ankle Vascular Index and Heart-Thigh β Index in a US Cohort: The MESA.  Hypertension  2025 Mar 07;. doi:10.1161/HYPERTENSIONAHA.124.23970
  36. McDowell K, Docherty KF, Campbell RT, Henderson AD, Jhund PS, Claggett BL, Desai AS, Lay-Flurrie J, Hofmeister L, Scalise A  et al.  Finerenone for Heart Failure and Risk Estimated by the PREDICT-HFpEF Model: A Secondary Analysis of FINEARTS-HF.  JAMA Cardiol  2025 Mar 05;. pii:e250025
  37. Eisinger-Mathason TSK, Leshin J, Lahoti V, Fridsma DB, Mucaj V, Kho AN  Data linkage multiplies research insights across diverse healthcare sectors.  Commun Med (Lond)  2025 Mar 04;5(1):58. pii:58
  38. Kanwar K, Ramachandran R, Stein JD, Andrews CA, Chaudhury AS, Ige M, Zhou X, Marwah S, Li Y, Evans CT  et al.  The Association of Social Determinants of Health on Monitoring for Disease Progression Among Patients With Primary Open-Angle Glaucoma.  Transl Vis Sci Technol  2025 Mar 03;14(3):15. pii:15
  39. Rojas JC, Lyons PG, Chhikara K, Chaudhari V, Bhavani SV, Nour M, Buell KG, Smith KD, Gao CA, Amagai S  et al.  A common longitudinal intensive care unit data format (CLIF) for critical illness research.  Intensive Care Med  2025 Mar;51(3):556-569. doi:10.1007/s00134-025-07848-7
  40. Shah SJ, Bonderman D, Borlaug BA, Cleland JGF, Lack G, Lu W, Voors AA, Zannad F, Gladwin MT  Macitentan for Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Pulmonary Vascular Disease: Results of the SERENADE Randomized Clinical Trial and Open-Label Extension Study.  Circ Heart Fail  2025 Mar;18(3):e011381. doi:10.1161/CIRCHEARTFAILURE.123.011381
  41. Gundogdu B, Chatterjee A, Medved M, Bagci U, Karczmar GS, Oto A  Physics-Informed Autoencoder for Prostate Tissue Microstructure Profiling with Hybrid Multidimensional MRI.  Radiol Artif Intell  2025 Mar;7(2):e240167. pii:e240167
  42. Davies MJ, van der Meer P, Verma S, Patel S, Chinnakondepalli KM, Borlaug BA, Butler J, Kitzman DW, Shah SJ, Harring S  et al.  Semaglutide in obesity-related heart failure with preserved ejection fraction and type 2 diabetes across baseline HbA1c levels (STEP-HFpEF DM): a prespecified analysis of heart failure and metabolic outcomes from a randomised, placebo-controlled trial.  Lancet Diabetes Endocrinol  2025 Mar;13(3):196-209. doi:10.1016/S2213-8587(24)00304-8
  43. Giuffrida AS, Sheriff S, Huang V, Weinberg BD, Cooper LAD, Liu Y, Soher BJ, Treadway M, Maudsley AA, Shim H  NNFit: A Self-Supervised Deep Learning Method for Accelerated Quantification of High-Resolution Short-Echo-Time MR Spectroscopy Datasets.  Radiol Artif Intell  2025 Mar;7(2):e230579. pii:e230579
  44. Zamani P, Shah SJ, Cohen JB, Zhao M, Yang W, Afable JL, Caturla M, Maynard H, Pourmussa B, Demastus C  et al.  Potassium Nitrate in Heart Failure With Preserved Ejection Fraction: A Randomized Clinical Trial.  JAMA Cardiol  2025 Mar 01;10(3):284-289. doi:10.1001/jamacardio.2024.4417
  45. Jain K, Katz R, Isakova T, Kizer JR, Sharma S, Psaty BM, Shah SJ, Ix J, Mehta R  Association of Fibroblast Growth Factor 23 and Cardiac Mechanics in the Cardiovascular Health Study.  Kidney360  2025 Mar 01;6(3):391-399. doi:10.34067/KID.0000000643
  46. Kruzan KP, Washburn JJ, Aaby D, Nguyen T, Mohr DC  Subgroups of non-suicidal self-injury in a large diverse sample of online help-seekers.  Front Psychiatry  2025;16:1513685. pii:1513685
  47. Goreish MH, Gennaro N, Perronne L, Durak G, Borhani AA, Savas H, Kelahan L, Avery R, Subedi K, Agirlar Trabzonlu T  et al.  Paradoxical Response to Neoadjuvant Therapy in Undifferentiated Pleomorphic Sarcoma: Increased Tumor Size on MRI Associated with Favorable Pathology.  Cancers (Basel)  2025 Feb 27;17(5). pii:830
  48. Meyerhoff J, Popowski SA, Lakhtakia T, Tack E, Kornfield R, Kruzan KP, Krause CJ, Nguyen T, Rushton K, Pisani AR  et al.  Automated Digital Safety Planning Interventions for Young Adults: Qualitative Study Using Online Co-design Methods.  JMIR Form Res  2025 Feb 26;9:e69602. pii:e69602
  49. Chen C, Nishtala A, Li E, Schultz WM, Baldridge AS, Groenendyk JW, Lee DC, Shah SJ, Burt RK, Freed BH  The effect of hematopoietic stem cell transplantation on cardiac mechanics in systemic sclerosis.  Int J Cardiovasc Imaging  2025 Feb 26;. doi:10.1007/s10554-025-03365-2
  50. Gennaro N, Soliman M, Borhani AA, Kelahan L, Savas H, Avery R, Subedi K, Trabzonlu TA, Krumpelman C, Yaghmai V  et al.  Delta Radiomics and Tumor Size: A New Predictive Radiomics Model for Chemotherapy Response in Liver Metastases from Breast and Colorectal Cancer.  Tomography  2025 Feb 20;11(3). pii:20

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