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Northwestern University Feinberg School of Medicine
Institute for Artificial Intelligence in Medicine

Publications

Browse the list below to see the latest scientific publications stemming from our institute faculty’s work. To view publications of specific AI faculty, please visit Membership and select a profile link.

  1. Schnauss M, Handa N, Nateghi R, Alam R, Jang JW, Huang MM, Abrams A, Neill C, Kumar SKSR, Hubbard N  et al.  Clinical and Reader Associated Correlates of Clinically Significant Magnetic Resonance Imaging-Invisible Prostate Cancer Based on Negative Scans.  J Urol  2026 Jul;216(1):25-33. doi:10.1097/JU.0000000000005028
  2. Peng L, Perronne L, Gennaro N, Rashidi AP, Kobus Z, Seo M, Borhani AA, Kelahan L, Subedi K, Savas H  et al.  Performance of deep learning-based segmentation of soft tissue sarcoma by MRI sequence, tumor type and location.  Skeletal Radiol  2026 Jul;55(7):1539-1548. doi:10.1007/s00256-026-05178-3
  3. Hosseini M, Eisenman D, Riddle J, Pyle S, Peters A, Cobb N, Holmes K  Guidelines needed for the use of AI in the preparation or review of IRB, IBC, and IACUC applications.  Account Res  2026 Jul;33(5):2612564. doi:10.1080/08989621.2025.2612564
  4. Lund LH, Barandiarán Aizpurua A, Bollano E, Braun O, Brouwer JLP, Buikema JW, Cannata A, Gardner RS, Handoko ML, Lang CC  et al.  Safety, pharmacokinetics, and exploratory efficacy of the oral ghrelin receptor agonist AC01 in heart failure with reduced ejection fraction (GOAL-HF1): a randomised, double-blind, placebo-controlled, phase 1b/2a study.  Lancet  2026 Jun 24;. pii:S0140-6736(26)00904-9
  5. Sharma A, Nateghi R, Ayad M, Cooper LAD, Goldstein JA  Machine learning identification of maternal inflammatory response and systemic inflammatory response from placental membrane whole slide images.  Placenta  2026 Jun 24;181:204-210. doi:10.1016/j.placenta.2026.05.028
  6. Lu H, Schneider SR, Pabón MA, Claggett BL, Miao MZ, Desai AS, Jhund PS, Henderson A, Lam CSP, Senni M  et al.  Sleep Apnea in Heart Failure With Mildly Reduced or Preserved Ejection Fraction: The FINEARTS-HF Trial.  JACC Heart Fail  2026 Jun 23;:103187. doi:10.1016/j.jchf.2026.103187
  7. Xian S, Smoller JW, Luo Y, Walunas TL, Liu C, Khan A, Weng C, Kullo IJ, Wei WQ, Jarvik GP  et al.  Unsupervised characterization of 100,272 EHR patients identifies high-risk groups and comorbidities linked to premature aging.  NPJ Digit Med  2026 Jun 23;. doi:10.1038/s41746-026-02913-x
  8. Bodelon C, Amgad M, Hodge JM, Elsebaie MAT, Landry M, Peng C, Tamimi RM, Kraft P, McCullough LE, Sherman ME  et al.  Effects of breast cancer risk factors on the tumor microenvironment: a morphological deep-learning analysis of three prospective cohorts.  NPJ Breast Cancer  2026 Jun 22;. doi:10.1038/s41523-026-00994-1
  9. Sethi I, Khan S, Lyons PG, Gao CA, Luo Y, Miltz D, Tovar S, Lohuis CT, Polly DM, Dave SB  et al.  Large Language Models Provide Accurate but Potentially Unsafe Answers to Multimodal Critical Care Medicine Board Review Questions.  Crit Care Med  2026 Jun 18;. doi:10.1097/CCM.0000000000007228
  10. Cheema BS, Boztepe B, Awofolaju MO, Hubbard MS, Marcus WB, Palella FJ, Abdel-Mohsen M, Liebovitz DM, Gill MK, Cotton RJ  et al.  Functional, molecular, and digital measurements of biological age.  J Clin Invest  2026 Jun 15;136(12). pii:e205777
  11. Xian S, Grabowska ME, Kullo IJ, Luo Y, Smoller JW, Walunas TL, Wei WQ, Jarvik G, Mooney S, Crosslin D  Author Correction: Transformer patient embedding using electronic health records enables patient stratification and progression analysis.  NPJ Digit Med  2026 Jun 11;9(1). pii:445
  12. Doi S, Kazui S, Akashi N, Patel RB, Komtebedde J, Mylavarapu U, Swarup V, Winkler S, Backhaus SJ, Litwin SE  et al.  Heart Failure Duration, Cardiac Remodeling, Dysfunction, and Hemodynamic Severity in HFpEF and HFmrEF: Insights From REDUCE LAP-HF II.  JACC Heart Fail  2026 Jun 05;:103167. doi:10.1016/j.jchf.2026.103167
  13. Bertoni AG, Bancks MP, Crago L, Chen H, Barr RG, Smith BM, Shah SJ  The Association of Race and Ethnicity with Six-Minute Walk Distance: The Multi-Ethnic Study of Atherosclerosis.  Ethn Dis  2026 Jan;36(1):22-29. doi:10.18865/EthnDis-2024-36
  14. Lewis ACF, Clayton EW, Bangash H, Bland HT, Bonini KE, Cimino JJ, Connolly JJ, Freimuth RR, Fullerton SM, Hakonarson H  et al.  Navigating data sharing in research.  Am J Hum Genet  2026 Jun 04;113(6):1159-1167. doi:10.1016/j.ajhg.2026.04.004
  15. Foà A, Pabon MA, Filippatos G, Claggett BL, Miao ZM, Jhund PS, Henderson A, Brinker M, Lage A, Hofmeister L  et al.  Effects of Finerenone on Sudden Death Across the Cardio-Kidney-Metabolic Landscape: A FINE-HEART Analysis.  J Am Coll Cardiol  2026 Jun 03;. pii:S0735-1097(26)06417-X
  16. Parkinson G, Patel R, Bergstrom C, Vadasz B, Amgad M, Cooper LAD, Sparano J, Lu J  Artificial Intelligence in Oncology: Clinical Applications, Challenges, and Opportunities.  Am Soc Clin Oncol Educ Book  2026 Jun;46(3):e520716. doi:10.1200/EDBK-26-520716
  17. Masri A, Cappelli F, Davis MK, Fontana M, Garcia-Pavia P, Gillmore JD, Hanna M, Obici L, Solomon SD, Sperry BW  et al.  Rationale and Design of CARDIO-TTRansform, a Phase 3 Trial of Eplontersen in Transthyretin Amyloid Cardiomyopathy.  Circ Heart Fail  2026 Jun;19(6):e014205. doi:10.1161/CIRCHEARTFAILURE.126.014205
  18. Shah SJ  Precision Medicine Is Not Optional, It's Oxygen: Reconciling Heart Failure With Preserved Ejection Fraction Trial Results Through the Lens of Phenotypic Diversity.  Struct Heart  2026 Jun;10(6):100778. pii:100778
  19. Lu H, Kosztin A, Claggett BL, Foà A, Pabón MA, Desai AS, Jhund PS, Henderson AD, Merkely B, Lam CSP  et al.  Biomarker, Functional Status, and Quality-of-Life Trajectories Before Modes of Death in Heart Failure: Post Hoc Analysis of the FINEARTS-HF Randomized Clinical Trial.  JAMA Cardiol  2026 Jun 01;11(6):574-582. doi:10.1001/jamacardio.2026.0682
  20. Banker M, do Nascimento JSP, Shownkeen H, Chang TR, Goldenberg F, Faine B, Cella D, Schuele SU, Luo Y, Tipton E  et al.  Prophylactic Antiseizure Medication in Patients with Lobar Intracerebral Hemorrhage.  Neurocrit Care  2026 Jun;44(3):850-856. doi:10.1007/s12028-025-02423-w
  21. Kaklamanos E, Kristinsdottir K, Wittbrodt M, Li M, Pitisuttithum P, Kou W, Keswani RN, Carlson D, Etemadi M, Pandolfino JE  From Pixels to Peristalsis: Comparing Achalasia Diagnosis With Artificial Intelligence With Expert Endoscopists.  Clin Gastroenterol Hepatol  2026 Jun;24(6):1542-1549. doi:10.1016/j.cgh.2025.09.034
  22. Yaku H, Burkhoff D, Borlaug BA, Lala A, Butler J, Rich S, Shah SJ  Oral Levosimendan for the Treatment of Pulmonary Hypertension due to Heart Failure With Preserved Ejection Fraction: Rationale and Design of the LEVEL Trial.  J Card Fail  2026 Jun;32(6):1059-1071. doi:10.1016/j.cardfail.2025.06.009
  23. Akerele AT, Hampton G, Kim J, Jaworski J, Lewis TJ, Khan A, Rasmussen-Torvik LJ, Luo Y, Jasper EA, Hellwege JN  et al.  Genetically-predicted placental gene expression links to uterine fibroids and endometriosis.  Placenta  2026 May 22;179:14-22. doi:10.1016/j.placenta.2026.03.023
  24. Perronne L, Gennaro N, Kobus Z, Seo M, Borhani AA, Kelahan L, Savas H, Avery R, Subedi K, Krumpelman C  et al.  A Predictive MRI Radiomics Model for Histologic Differentiation in Soft Tissue Sarcomas.  Cancers (Basel)  2026 May 21;18(10). pii:1667
  25. Singla A, Park S, Pedamallu H, Chen K, Robelly B, Rebello C, Lantz C, Zhao L, LaCombe R, Sinha R  et al.  Diagnostic Performance and Resource Utilization of Combining Blood Gene Expression, Cell-Free DNA, and Urine Chemokines for Monitoring Kidney Rejection.  Clin J Am Soc Nephrol  2026 May 21;. doi:10.2215/CJN.0000001075
  26. Chakrabarty RP, Van Vranken JG, Aoi Y, Poor TA, McElroy GS, Vasan K, Soliman SHA, Iwanaszko M, Grant RA, Howard BC  et al.  Mitochondrial L-2-hydroxyglutarate is a physiological signalling metabolite.  Nature  2026 May 20;. doi:10.1038/s41586-026-10564-x
  27. Henderson AD, Docherty KF, Talebi A, Kondo T, Petrie MC, Claggett BL, Desai AS, Vaduganathan M, Atherton JJ, Bauersachs J  et al.  A Bayesian analysis of finerenone in heart failure with mildly reduced and preserved ejection fraction: a pre-specified analysis of FINEARTS-HF.  Eur Heart J Cardiovasc Pharmacother  2026 May 19;12(3):176-185. doi:10.1093/ehjcvp/pvag010
  28. Makuvire TT, Lam CSP, Pabon MA, Claggett BL, Kulac IJ, Desai AS, Jhund PS, Henderson AD, Amarante F, Chen M  et al.  Geographic Variation in Heart Failure With Mildly Reduced or Preserved Ejection Fraction: Insights From the FINEARTS-HF Trial.  JACC Heart Fail  2026 May 15;:103105. doi:10.1016/j.jchf.2026.103105
  29. Helseth R, Claggett BL, Bhatt A, Vardeny O, Lu H, Desai AS, Jhund PS, Henderson A, Lam CSP, Senni M  et al.  Viral respiratory tract infections in heart failure: the FINEARTS-HF trial.  Eur Heart J  2026 May 11;. pii:ehag384
  30. Hamatani Y, Claggett BL, Kulac IJ, Desai AS, Jhund PS, Henderson AD, Lam CSP, Senni M, Shah SJ, Voors AA  et al.  Finerenone, polypharmacy, and clinical outcomes in heart failure: pre-specified analysis from the FINEARTS-HF trial.  Eur J Heart Fail  2026 May 11;28(2):194-203. doi:10.1093/ejhf/xuag030
  31. Khan SS, Lloyd-Jones D, Pagidipati NJ, Shah SJ, Pawlowski C, Hogan L, Williams J, Leopold J  HFpEF Explained - Living with HFpEF.  N Engl J Med  2026 May 07;394(18):e35. doi:10.1056/NEJMp2516849
  32. Hafer N, Cielo K, Duguid P, Dunn M, Gholami M, Holmes K, Hunt J, Kane C, Moussatche P, Navarro C  et al.  Crowdsourced educational resource to distinguish Translational Science (TS) from Translational Research (TR).  J Clin Transl Sci  2026;10(1):e87. pii:e87
  33. Fejzo M, Wang X, Tan Q, Zöllner J, Pujol-Gualdo N, Laisk T, , Finer S, van Heel DA,   et al.  Publisher Correction: Multi-ancestry genome-wide association study of severe pregnancy nausea and vomiting.  Nat Genet  2026 May;58(5):1186. doi:10.1038/s41588-026-02608-9
  34. Marrero N, Jha K, Grant JK, Razavi AC, Budoff MJ, Shah SJ, Rotter JI, Blumenthal RS, Post WS, Gulati M  et al.  Sex-Specific Prognostic Value of Aortic Valve Calcium and the Risk for Aortic Stenosis: Multi-Ethnic Study of Atherosclerosis (MESA).  Circ Cardiovasc Imaging  2026 May;19(5):e018849. doi:10.1161/CIRCIMAGING.125.018849
  35. Peters AE, Ahmad FS, Martyn T, Grogan M, Hanna M, Maurer MS, Goyal P  Screening Strategies for Identification of Transthyretin Amyloid Cardiomyopathy.  JACC Heart Fail  2026 May;14(5):103018. doi:10.1016/j.jchf.2026.103018
  36. Michelson KN, Hayes A, Barrera L, James K, Miller C, Guzman Z, Torres N, McNicholas A, Becker AB  Pilot Study of a Bereavement Referral Program for Parents Following Perinatal Death.  J Pain Symptom Manage  2026 May;71(5):581-591.e3. doi:10.1016/j.jpainsymman.2026.01.004
  37. Kremer N, Polo-Silveira L, Bajaj S, Sattler S, Halpern AC, Bagci U, Dusza SW, Kose K, Weber J, D'Alessandro B  et al.  Comparing dermatologists' and artificial intelligence heat maps in dermoscopic image analysis via eye tracking.  J Am Acad Dermatol  2026 May;94(5):1461-1468. doi:10.1016/j.jaad.2025.12.104
  38. Owen AL, Langshur S, Doblin BH, Vargas MC, Hinami K, Kho AN, Liss DT, O'Brien MJ  Correlates of Diagnostic Codes for Documenting Housing Instability: A Citywide Cohort Study.  Am J Prev Med  2026 May;70(5):108214. doi:10.1016/j.amepre.2025.108214
  39. Mc Causland FR, Chatur S, Vaduganathan M, Claggett BL, Kulac IJ, Desai AS, Jhund PS, Henderson AD, Rohwedder K, Amarante F  et al.  Finerenone and Cardiovascular Outcomes According to Baseline Kidney Function in Patients With Heart Failure: The FINEARTS-HF Trial.  JACC Heart Fail  2026 May;14(5):102778. doi:10.1016/j.jchf.2025.102778
  40. Shah SJ, Khan S, Lloyd-Jones D, Pagidipati NJ, Pawlowski C, Kirk K, Hogan L, Williams J, Leopold J  HFpEF Explained - Managing HFpEF in Primary Care.  N Engl J Med  2026 Apr 30;394(17):e32. doi:10.1056/NEJMp2516848
  41. Hong SS, Utz Z, Hosseini M, Zanchettin C, Tejedor Navarro H, Holmes K, Wetterstrand KA, Bates SA, Nunes Amaral LA, Donohue CR  et al.  A digital archive reveals how a funding agency cooperated with academics to support the nascent field of genomics.  Nat Commun  2026 Apr 29;17(1). pii:3621
  42. Mohamedali A, Chaudhury AS, Rivera AS, Zhou X, Stein JD, Andrews CA, Li Y, Marwah S, Shah R, Kanwar K  et al.  Linking multicenter electronic health records with socioeconomic data to examine receipt of standard versus premium intraocular lenses.  AJO Int  2026 Apr 28;3(1). pii:100209
  43. Amagai S, Powell EC, Alpern ER, Florin TA, Li Y, Liebovitz D, Luo Y, Espinoza J, Wong AF, Ramgopal S  Performance of Open-Source LLMs in Identifying Pediatric Pneumonia From Free-Text Chest Radiograph Reports.  Pediatr Emerg Care  2026 Apr 21;. doi:10.1097/PEC.0000000000003616
  44. Luo Y  Cardiovascular Endpoint Adjudication in Clinical Trials: A Proactive and Collaborative AI Approach.  J Am Coll Cardiol  2026 Apr 21;87(15):1870-1872. doi:10.1016/j.jacc.2025.12.040
  45. Oshinubi K, Chen Y, Doerry E, Gel ES, Hepp C, Lant T, Mehrotra S, Sabo S, Mihaljevic J  A systematic review of spatial epidemiological modeling approaches applied during the COVID-19 pandemic.  BMC Public Health  2026 Apr 15;26(1). pii:1691
  46. Hosseini M, Earp BD, Porsdam Mann S, Holmes K  Generative AI can and should accelerate research evaluation reform to better recognize 'distinctly human contributions'.  Res Eval  2026;35:rvag020. pii:rvag020
  47. Hamatani Y, Ostrominski JW, Lu H, Claggett BL, Miao ZM, Desai AS, Jhund PS, Henderson AD, Lam CSP, Senni M  et al.  Effects of Finerenone Across a Range of Heart Failure Duration: A Prespecified Analysis of the FINEARTS-HF Trial.  Eur J Heart Fail  2026 Apr 08;. pii:xuag119
  48. Olson EM, Cohen ER, Cheema YR, Bockrath R, O'Brien CL, Whitlow GA, Hufmeyer K, Sanguino SM, Green MM, Garcia PM  et al.  Impact of Livestreaming Pre-Clerkship Lectures: A Prospective Pilot with Multiyear Follow-up.  Med Sci Educ  2026 Apr;36(2):755-763. doi:10.1007/s40670-025-02629-9
  49. Hosseini M, Kerridge S, Allen L, Kiermer V, Holmes K  Enhancing, Understanding and Adoption of the Contributor Roles Taxonomy (CRediT).  Learn Publ  2026 Apr;39(2). pii:e2048
  50. Cohen A, Michelson KN, Macy ML, Heard-Garris N, Kan K  The Association Between Shared Decision-Making and Child Health in the General Pediatric Population.  Matern Child Health J  2026 Apr;30(4):575-583. doi:10.1007/s10995-026-04251-6

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