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Northwestern University Feinberg School of Medicine
Institute for Artificial Intelligence in Medicine

Publications

Browse the list below to see the latest scientific publications stemming from our institute faculty’s work. To view publications of specific AI faculty, please visit Membership and select a profile link.

  1. Yaku H, Fudim M, Shah SJ  Role of splanchnic circulation in the pathogenesis of heart failure: State-of-the-art review.  J Cardiol  2024 May;83(5):330-337. doi:10.1016/j.jjcc.2024.02.004
  2. Lakhtakia T, Smith SR, Mohr DC, Stamatis CA  Longitudinal associations of daily affective dynamics with depression, generalized anxiety, and social anxiety symptoms.  J Affect Disord  2024 May 01;352:437-444. doi:10.1016/j.jad.2024.01.250
  3. Adler DA, Stamatis CA, Meyerhoff J, Mohr DC, Wang F, Aranovich GJ, Sen S, Choudhury T  Measuring algorithmic bias to analyze the reliability of AI tools that predict depression risk using smartphone sensed-behavioral data.  Npj Ment Health Res  2024 Apr 22;3(1):17. pii:17
  4. Jani VP, Strom JB, Gami A, Beussink-Nelson L, Patel R, Michos ED, Shah SJ, Freed BH, Mukherjee M  Optimal Method for Assessing Right Ventricular to Pulmonary Arterial Coupling and Subclinical Right Ventricular Dysfunction in Older Aged Healthy Adults: The Multi-Ethnic Study of Atherosclerosis.  Am J Cardiol  2024 Apr 19;. pii:S0002-9149(24)00266-2
  5. Kosiborod MN, Petrie MC, Borlaug BA, Butler J, Davies MJ, Hovingh GK, Kitzman DW, Møller DV, Treppendahl MB, Verma S  et al.  Semaglutide in Patients with Obesity-Related Heart Failure and Type 2 Diabetes.  N Engl J Med  2024 Apr 18;390(15):1394-1407. doi:10.1056/NEJMoa2313917
  6. Patel RB, Silvestry FE, Komtebedde J, Solomon SD, Hasenfuß G, Litwin SE, Borlaug BA, Price MJ, Kawash R, Hummel SL  et al.  Atrial Shunt Device Effects on Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction: The REDUCE LAP-HF II Randomized Clinical Trial.  JAMA Cardiol  2024 Apr 17;. pii:e240520
  7. Strom JB, Mukherjee M, Beussink-Nelson L, Gardin JM, Freed BH, Shah SJ, Afilalo J  Reference Values for Indexed Echocardiographic Chamber Sizes in Older Adults: The Multi-Ethnic Study of Atherosclerosis.  J Am Heart Assoc  2024 Apr 16;13(8):e034029. doi:10.1161/JAHA.123.034029
  8. Pabón MA, Wang X, Lam CSP, O'Meara E, Vaduganathan M, Claggett BL, Foà A, Lu H, Langkilde AM, De Boer RA  et al.  Sex Differences in Heart Failure With Improved Ejection Fraction: The DELIVER Trial.  JACC Heart Fail  2024 Apr 08;. pii:S2213-1779(24)00265-8
  9. Butler J, Shah SJ, Petrie MC, Borlaug BA, Abildstrøm SZ, Davies MJ, Hovingh GK, Kitzman DW, Møller DV, Verma S  et al.  Semaglutide versus placebo in people with obesity-related heart failure with preserved ejection fraction: a pooled analysis of the STEP-HFpEF and STEP-HFpEF DM randomised trials.  Lancet  2024 Apr 04;. pii:S0140-6736(24)00469-0
  10. Selvaraj S, Patel S, Sauer AJ, McGarrah RW, Jones P, Kwee LC, Windsor SL, Ilkayeva O, Muehlbauer MJ, Newgard CB  et al.  Targeted Metabolomic Profiling of Dapagliflozin in Heart Failure With Preserved Ejection Fraction: The PRESERVED-HF Trial.  JACC Heart Fail  2024 Apr 03;. pii:S2213-1779(24)00182-3
  11. Ahmad FS, Hu TL, Adler ED, Petito LC, Wehbe RM, Wilcox JE, Mutharasan RK, Nardone B, Tadel M, Greenberg B  et al.  Performance of risk models to predict mortality risk for patients with heart failure: evaluation in an integrated health system.  Clin Res Cardiol  2024 Apr 02;. doi:10.1007/s00392-024-02433-2
  12. Chiu L, Agrawal V, Armstrong D, Brittain E, Collins S, Hemnes AR, Hill JA, Lindenfeld J, Shah SJ, Stevenson LW  et al.  Correlates of Plasma NT-proBNP/Cyclic GMP Ratio in Heart Failure With Preserved Ejection Fraction: An Analysis of the RELAX Trial.  J Am Heart Assoc  2024 Apr 02;13(7):e031796. doi:10.1161/JAHA.123.031796
  13. Jonathan GK, Abitante G, McBride A, Bernstein-Sandler M, Babington P, Dopke CA, Rossom RC, Mohr DC, Goulding EH  LiveWell, a smartphone-based self-management intervention for bipolar disorder: Intervention participation and usability analysis.  J Affect Disord  2024 Apr 01;350:926-936. doi:10.1016/j.jad.2024.01.099
  14. Huang J, Galal G, Mukhin V, Etemadi M, Tanna AP  Prediction and Detection of Glaucomatous Visual Field Progression Using Deep Learning on Macular Optical Coherence Tomography.  J Glaucoma  2024 Apr 01;33(4):246-253. doi:10.1097/IJG.0000000000002359
  15. Hitsman B, Papandonatos GD, Fox EN, Bauer AM, Gollan JK, Huffman MD, Mohr DC, Leone FT, Khan SS, Achenbach CJ  et al.  Effect of early medication adherence on behavioral treatment utilization and smoking cessation among individuals with current or past major depressive disorder.  Addict Behav  2024 Apr;151:107952. doi:10.1016/j.addbeh.2024.107952
  16. Peikert A, Bart BA, Vaduganathan M, Claggett BL, Kulac IJ, Kosiborod MN, Desai AS, Jhund PS, Lam CSP, Inzucchi SE  et al.  Contemporary Use and Implications of Beta-Blockers in Patients With HFmrEF or HFpEF: The DELIVER Trial.  JACC Heart Fail  2024 Apr;12(4):631-644. doi:10.1016/j.jchf.2023.09.007
  17. Xiang G, He X, Giardine BM, Isaac KJ, Taylor DJ, McCoy RC, Jansen C, Keller CA, Wixom AQ, Cockburn A  et al.  Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes.  bioRxiv  2024 Mar 29;. pii:2023.04.02.535219
  18. Kim M, Wang P, Clow PA, Chien IE, Wang X, Peng J, Chai H, Liu X, Lee B, Ngan CY  et al.  Multifaceted roles of cohesin in regulating transcriptional loops.  bioRxiv  2024 Mar 27;. pii:2024.03.25.586715
  19. Anibal JT, Landa AJ, Hang NTT, Song MJ, Peltekian AK, Shin A, Huth HB, Hazen LA, Christou AS, Rivera J  et al.  Omicron detection with large language models and YouTube audio data.  medRxiv  2024 Mar 27;. pii:2022.09.13.22279673
  20. Mathew DT, Peigh G, Lima JAC, Bielinski SJ, Larson NB, Allison MA, Shah SJ, Patel RB  Associations of Circulating Vascular Cell Adhesion Molecule-1 and Intercellular Adhesion Molecule-1 With Long-Term Cardiac Function.  J Am Heart Assoc  2024 Mar 19;13(6):e032213. pii:e032213
  21. Chaudhuri SM, Weinberg SE, Wang D, Yalom LK, Montauti E, Iyer R, Tang AY, Torres Acosta MA, Shen J, Mani NL  et al.  Mediator complex subunit 1 architects a tumorigenic Treg cell program independent of inflammation.  Cell Rep Med  2024 Mar 19;5(3):101441. pii:101441
  22. Tran SD, Lin J, Galvez C, Rasmussen LV, Pacheco J, Perottino GM, Rahbari KJ, Miller CD, John JD, Theros J  et al.  Rapid identification of inflammatory arthritis and associated adverse events following immune checkpoint therapy: a machine learning approach.  Front Immunol  2024;15:1331959. pii:1331959
  23. Peikert A, Vaduganathan M, Claggett BL, Kulac IJ, Foà A, Desai AS, Jhund PS, Carberry J, Lam CSP, Kosiborod MN  et al.  Dapagliflozin in patients with heart failure and previous myocardial infarction: A participant-level pooled analysis of DAPA-HF and DELIVER.  Eur J Heart Fail  2024 Mar 15;. doi:10.1002/ejhf.3184
  24. Li Y, Wu X, Fang D, Luo Y  Informing immunotherapy with multi-omics driven machine learning.  NPJ Digit Med  2024 Mar 14;7(1):67. pii:67
  25. Kiraly AP, Cunningham CA, Najafi R, Nabulsi Z, Yang J, Lau C, Ledsam JR, Ye W, Ardila D, McKinney SM  et al.  Assistive AI in Lung Cancer Screening: A Retrospective Multinational Study in the United States and Japan.  Radiol Artif Intell  2024 Mar 13;:e230079. doi:10.1148/ryai.230079
  26. McMurray JJV, Docherty KF, de Boer RA, Hammarstedt A, Kitzman DW, Kosiborod MN, Maria Langkilde A, Reicher B, Senni M, Shah SJ  et al.  Effect of Dapagliflozin Versus Placebo on Symptoms and 6-Minute Walk Distance in Patients With Heart Failure: The DETERMINE Randomized Clinical Trials.  Circulation  2024 Mar 12;149(11):825-838. doi:10.1161/CIRCULATIONAHA.123.065061
  27. Adekkanattu P, Furmanchuk A, Wu Y, Pathak A, Patra BG, Bost S, Morrow D, Wang GH, Yang Y, Forrest NJ  et al.  Detection of Personal and Family History of Suicidal Thoughts and Behaviors using Deep Learning and Natural Language Processing: A Multi-Site Study.  Res Sq  2024 Mar 11;. pii:rs.3.rs-4014472
  28. Dalal PJ, Giro P, Rasmussen-Torvik LJ, Yancy CW, Shah SJ, Reiner AP, Haring B, Martin LW, Wells GL, Manson JE  et al.  Heart Failure Risk Among African-American Women With an ICAM1 Missense Variant.  JACC Heart Fail  2024 Mar 11;. pii:S2213-1779(24)00145-8
  29. Atreya MR, Bennett TD, Geva A, Faustino EVS, Rogerson CM, Lutfi R, Cvijanovich NZ, Bigham MT, Nowak J, Schwarz AJ  et al.  Biomarker Assessment of a High-Risk, Data-Driven Pediatric Sepsis Phenotype Characterized by Persistent Hypoxemia, Encephalopathy, and Shock.  Pediatr Crit Care Med  2024 Mar 11;. doi:10.1097/PCC.0000000000003499
  30. Szczepanski A, Tsuboyama N, Lyu H, Wang P, Beytullahoglu O, Zhang T, Singer BD, Yue F, Zhao Z, Wang L  A SWI/SNF-dependent transcriptional regulation mediated by POU2AF2/C11orf53 at enhancer.  Nat Commun  2024 Mar 07;15(1):2067. pii:2067
  31. Hosseini M, Holcombe AO, Kovacs M, Zwart H, Katz DS, Holmes K  Group authorship, an excellent opportunity laced with ethical, legal and technical challenges.  Account Res  2024 Mar 06;:1-23. doi:10.1080/08989621.2024.2322557
  32. Bhatt AS, Vaduganathan M, Claggett BL, Kulac IJ, Anand IS, Desai AS, Fang JC, Hernandez AF, Jhund PS, Kosiborod MN  et al.  Cost Effectiveness of Dapagliflozin for Heart Failure Across the Spectrum of Ejection Fraction: An Economic Evaluation Based on Pooled, Individual Participant Data From the DELIVER and DAPA-HF Trials.  J Am Heart Assoc  2024 Mar 05;13(5):e032279. pii:e032279
  33. Deng Y, Pacheco JA, Ghosh A, Chung A, Mao C, Smith JC, Zhao J, Wei WQ, Barnado A, Dorn C  et al.  Natural language processing to identify lupus nephritis phenotype in electronic health records.  BMC Med Inform Decis Mak  2024 Mar 03;22(Suppl 2):348. pii:348
  34. Beussink-Nelson L, Freed BH, Chirinos JA, Brubaker PH, Kitzman DW, Yeboah J, Rosas SE, Hu M, Lima JAC, Pandit J  et al.  Multi-Ethnic Study of Atherosclerosis Early Heart Failure Study: Rationale, Design, and Baseline Characteristics.  Circ Heart Fail  2024 Mar;17(3):e010289. doi:10.1161/CIRCHEARTFAILURE.122.010289
  35. Suzuki K, Hatzikotoulas K, Southam L, Taylor HJ, Yin X, Lorenz KM, Mandla R, Huerta-Chagoya A, Melloni GEM, Kanoni S  et al.  Genetic drivers of heterogeneity in type 2 diabetes pathophysiology.  Nature  2024 Mar;627(8003):347-357. doi:10.1038/s41586-024-07019-6
  36. Vardeny O, Desai AS, Jhund PS, Fang JC, Claggett B, de Boer RA, Hernandez AF, Inzucchi SE, Kosiborod MN, Lam CSP  et al.  Dapagliflozin and Mode of Death in Heart Failure With Improved Ejection Fraction: A Post Hoc Analysis of the DELIVER Trial.  JAMA Cardiol  2024 Mar 01;9(3):283-289. doi:10.1001/jamacardio.2023.5318
  37. Irmakci I, Nateghi R, Zhou R, Vescovo M, Saft M, Ross AE, Yang XJ, Cooper LAD, Goldstein JA  Tissue Contamination Challenges the Credibility of Machine Learning Models in Real World Digital Pathology.  Mod Pathol  2024 Mar;37(3):100422. doi:10.1016/j.modpat.2024.100422
  38. Butt JH, Jering K, DE Boer RA, Claggett BL, Desai AS, Hernandez AF, Inzucchi SE, Jhund PS, Køber L, Kosiborod MN  et al.  Heart Failure, Investigator-Reported Sleep Apnea and Dapagliflozin: A Patient-Level Pooled Meta-Analysis of DAPA-HF and DELIVER.  J Card Fail  2024 Mar;30(3):436-448. doi:10.1016/j.cardfail.2023.08.027
  39. Santos CAQ, Tseng M, Martinez AI, Shankaran S, Hodgson HA, Ahmad FS, Zhang H, Sievert DM, Trick WE  Comparative antimicrobial use in coronavirus disease 2019 (COVID-19) and non-COVID-19 inpatients from 2019 to 2020: A multicenter ecological study.  Infect Control Hosp Epidemiol  2024 Mar;45(3):335-342. doi:10.1017/ice.2023.180
  40. Doiron JE, Li Z, Yu X, LaPenna KB, Quiriarte H, Allerton TD, Koul K, Malek A, Shah SJ, Sharp TE  et al.  Early Renal Denervation Attenuates Cardiac Dysfunction in Heart Failure With Preserved Ejection Fraction.  J Am Heart Assoc  2024 Feb 20;13(4):e032646. pii:e032646
  41. Li Z, Lei Y, Bui Q, DePaul O, Nicol GE, Mohr DC, Lee SI, Fong MWM, Metts CL, Tomazin SE  et al.  A Digital Intervention to Promote Self-Management Self-Efficacy Among Community-Dwelling Individuals With Stroke: Pilot Randomized Controlled Trial.  JMIR Rehabil Assist Technol  2024 Feb 19;11:e50863. pii:e50863
  42. Yoon E, Hur S, Opsasnick L, Huang W, Batio S, Curtis LM, Benavente JY, Lewis-Thames MW, Liebovitz DM, Wolf MS  et al.  Disparities in Patient Portal Use Among Adults With Chronic Conditions.  JAMA Netw Open  2024 Feb 05;7(2):e240680. pii:e240680
  43. Mc Causland FR, Claggett BL, Vaduganathan M, Desai A, Jhund P, Vardeny O, Fang JC, de Boer RA, Docherty KF, Hernandez AF  et al.  Decline in Estimated Glomerular Filtration Rate After Dapagliflozin in Heart Failure With Mildly Reduced or Preserved Ejection Fraction: A Prespecified Secondary Analysis of the DELIVER Randomized Clinical Trial.  JAMA Cardiol  2024 Feb 01;9(2):144-152. doi:10.1001/jamacardio.2023.4664
  44. Tager JB, Hinojosa JT, LiaBraaten BM, Balistreri KA, Aniciete D, Charleston E, Frader JE, White DB, Clayman ML, Sorce LR  et al.  Challenges of Families of Patients Hospitalized in the PICU: A Preplanned Secondary Analysis From the Navigate Dataset.  Pediatr Crit Care Med  2024 Feb 01;25(2):128-138. doi:10.1097/PCC.0000000000003385
  45. Gudenkauf B, Shaya G, Mukherjee M, Michos ED, Madrazo J, Mathews L, Shah SJ, Sharma K, Hays AG  Insulin resistance is associated with subclinical myocardial dysfunction and reduced functional capacity in heart failure with preserved ejection fraction.  J Cardiol  2024 Feb;83(2):100-104. doi:10.1016/j.jjcc.2023.06.008
  46. Munsell EGS, Bui Q, Kaufman KJ, Tomazin SE, Regan BA, Lenze EJ, Lee JM, Mohr DC, Fong MWM, Metts CL  et al.  Intraindividual variability in post-stroke cognition and its relationship with activities of daily living and social functioning: an ecological momentary assessment approach.  Top Stroke Rehabil  2024 Jan 26;:1-12. doi:10.1080/10749357.2024.2307203
  47. Belue MJ, Harmon SA, Yang D, An JY, Gaur S, Law YM, Turkbey E, Xu Z, Tetreault J, Lay NS  et al.  Deep Learning-Based Detection and Classification of Bone Lesions on Staging Computed Tomography in Prostate Cancer: A Development Study.  Acad Radiol  2024 Jan 22;. pii:S1076-6332(24)00008-4
  48. Tavolara TE, Niazi MKK, Feldman AL, Jaye DL, Flowers C, Cooper LAD, Gurcan MN  Translating prognostic quantification of c-MYC and BCL2 from tissue microarrays to whole slide images in diffuse large B-cell lymphoma using deep learning.  Diagn Pathol  2024 Jan 19;19(1):17. pii:17
  49. Maning J, Shah SJ, Patel RB  With Great Data Come Great Responsibilities: The Cardiac Amyloidosis Registry Study.  J Card Fail  2024 Jan 18;. pii:S1071-9164(24)00014-9
  50. Mathur R, Wang Q, Schupp PG, Nikolic A, Hilz S, Hong C, Grishanina NR, Kwok D, Stevers NO, Jin Q  et al.  Glioblastoma evolution and heterogeneity from a 3D whole-tumor perspective.  Cell  2024 Jan 18;187(2):446-463.e16. doi:10.1016/j.cell.2023.12.013