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Northwestern University Feinberg School of Medicine
Institute for Artificial Intelligence in Medicine

Publications

Browse the list below to see the latest scientific publications stemming from our institute faculty’s work. To view publications of specific AI faculty, please visit Membership and select a profile link.

  1. Hamed M, Naderian M, Bangash H, Hernandez V, Shaibi GQ, Arslan M, Saadatagah S, Sherafati A, Miller A, Kamzabek A  et al.  Implementing a Multi-Ancestry Polygenic Risk Score for Coronary Heart Disease in a Diverse Cohort.  Genet Med  2026 Jul 11;:102662. doi:10.1016/j.gim.2026.102662
  2. He Y, Zhao Y, Zhang R, Yang H, Zhang Z, Ren P, Luo C, Zhang P, Zhang Z, Hou S  et al.  Integrating cytological images and spatial transcriptomics for cell segmentation with DISSECT.  Nat Comput Sci  2026 Jul 09;. doi:10.1038/s43588-026-01020-x
  3. Ostrominski JW, Claggett BL, Kulac IJ, Desai AS, Jhund PS, Henderson A, Lam CSP, Senni M, Shah SJ, Voors AA  et al.  Finerenone and Blood Pressure in Heart Failure With Mildly Reduced or Preserved Ejection Fraction: The FINEARTS-HF Randomized Clinical Trial.  JAMA Cardiol  2026 Jul 08;. pii:e262104
  4. Willis A, Lee C, Krogue J, Wickramanayake A, Young-Lin N, Caron S, Cheruiyot P, Watters A, Martín A, Tiyasirichokchai T  et al.  Generalization of AI-Based Gestational Age Assessment Using Blind Sweep Ultrasonography.  JAMA Netw Open  2026 Jul 01;9(7):e2622484. pii:e2622484
  5. Schnauss M, Handa N, Nateghi R, Alam R, Jang JW, Huang MM, Abrams A, Neill C, Kumar SKSR, Hubbard N  et al.  Clinical and Reader Associated Correlates of Clinically Significant Magnetic Resonance Imaging-Invisible Prostate Cancer Based on Negative Scans.  J Urol  2026 Jul;216(1):25-33. doi:10.1097/JU.0000000000005028
  6. Peng L, Perronne L, Gennaro N, Rashidi AP, Kobus Z, Seo M, Borhani AA, Kelahan L, Subedi K, Savas H  et al.  Performance of deep learning-based segmentation of soft tissue sarcoma by MRI sequence, tumor type and location.  Skeletal Radiol  2026 Jul;55(7):1539-1548. doi:10.1007/s00256-026-05178-3
  7. Hosseini M, Eisenman D, Riddle J, Pyle S, Peters A, Cobb N, Holmes K  Guidelines needed for the use of AI in the preparation or review of IRB, IBC, and IACUC applications.  Account Res  2026 Jul;33(5):2612564. doi:10.1080/08989621.2025.2612564
  8. Ayad M, Cooper LAD, Brat DJ  Inferring DNA Methylation Class from Digitized Pathology Images and AI: A Worthy and Timely Application with Room for Improved Clinical Performance.  Neuro Oncol  2026 Jun 30;. pii:noag149
  9. Lund LH, Barandiarán Aizpurua A, Bollano E, Braun O, Brouwer JLP, Buikema JW, Cannata A, Gardner RS, Handoko ML, Lang CC  et al.  Safety, pharmacokinetics, and exploratory efficacy of the oral ghrelin receptor agonist AC01 in heart failure with reduced ejection fraction (GOAL-HF1): a randomised, double-blind, placebo-controlled, phase 1b/2a study.  Lancet  2026 Jun 24;. pii:S0140-6736(26)00904-9
  10. Sharma A, Nateghi R, Ayad M, Cooper LAD, Goldstein JA  Machine learning identification of maternal inflammatory response and systemic inflammatory response from placental membrane whole slide images.  Placenta  2026 Jun 24;181:204-210. doi:10.1016/j.placenta.2026.05.028
  11. Lu H, Schneider SR, Pabón MA, Claggett BL, Miao MZ, Desai AS, Jhund PS, Henderson A, Lam CSP, Senni M  et al.  Sleep Apnea in Heart Failure With Mildly Reduced or Preserved Ejection Fraction: The FINEARTS-HF Trial.  JACC Heart Fail  2026 Jun 23;:103187. doi:10.1016/j.jchf.2026.103187
  12. Xian S, Smoller JW, Luo Y, Walunas TL, Liu C, Khan A, Weng C, Kullo IJ, Wei WQ, Jarvik GP  et al.  Unsupervised characterization of 100,272 EHR patients identifies high-risk groups and comorbidities linked to premature aging.  NPJ Digit Med  2026 Jun 23;. doi:10.1038/s41746-026-02913-x
  13. Bodelon C, Amgad M, Hodge JM, Elsebaie MAT, Landry M, Peng C, Tamimi RM, Kraft P, McCullough LE, Sherman ME  et al.  Effects of breast cancer risk factors on the tumor microenvironment: a morphological deep-learning analysis of three prospective cohorts.  NPJ Breast Cancer  2026 Jun 22;. doi:10.1038/s41523-026-00994-1
  14. Sethi I, Khan S, Lyons PG, Gao CA, Luo Y, Miltz D, Tovar S, Lohuis CT, Polly DM, Dave SB  et al.  Large Language Models Provide Accurate but Potentially Unsafe Answers to Multimodal Critical Care Medicine Board Review Questions.  Crit Care Med  2026 Jun 18;. doi:10.1097/CCM.0000000000007228
  15. Oh D, Choi HS, Mohr DC, Na H  Effects of a mobile-based self-management program on mental health in young adults: a randomized controlled trial.  Front Public Health  2026;14:1830292. pii:1830292
  16. Cheema BS, Boztepe B, Awofolaju MO, Hubbard MS, Marcus WB, Palella FJ, Abdel-Mohsen M, Liebovitz DM, Gill MK, Cotton RJ  et al.  Functional, molecular, and digital measurements of biological age.  J Clin Invest  2026 Jun 15;136(12). pii:e205777
  17. Xian S, Grabowska ME, Kullo IJ, Luo Y, Smoller JW, Walunas TL, Wei WQ, Jarvik G, Mooney S, Crosslin D  Author Correction: Transformer patient embedding using electronic health records enables patient stratification and progression analysis.  NPJ Digit Med  2026 Jun 11;9(1). pii:445
  18. Doi S, Kazui S, Akashi N, Patel RB, Komtebedde J, Mylavarapu U, Swarup V, Winkler S, Backhaus SJ, Litwin SE  et al.  Heart Failure Duration, Cardiac Remodeling, Dysfunction, and Hemodynamic Severity in HFpEF and HFmrEF: Insights From REDUCE LAP-HF II.  JACC Heart Fail  2026 Jun 05;:103167. doi:10.1016/j.jchf.2026.103167
  19. Bertoni AG, Bancks MP, Crago L, Chen H, Barr RG, Smith BM, Shah SJ  The Association of Race and Ethnicity with Six-Minute Walk Distance: The Multi-Ethnic Study of Atherosclerosis.  Ethn Dis  2026 Jan;36(1):22-29. doi:10.18865/EthnDis-2024-36
  20. Lewis ACF, Clayton EW, Bangash H, Bland HT, Bonini KE, Cimino JJ, Connolly JJ, Freimuth RR, Fullerton SM, Hakonarson H  et al.  Navigating data sharing in research.  Am J Hum Genet  2026 Jun 04;113(6):1159-1167. doi:10.1016/j.ajhg.2026.04.004
  21. Foà A, Pabon MA, Filippatos G, Claggett BL, Miao ZM, Jhund PS, Henderson A, Brinker M, Lage A, Hofmeister L  et al.  Effects of Finerenone on Sudden Death Across the Cardio-Kidney-Metabolic Landscape: A FINE-HEART Analysis.  J Am Coll Cardiol  2026 Jun 03;. pii:S0735-1097(26)06417-X
  22. Parkinson G, Patel R, Bergstrom C, Vadasz B, Amgad M, Cooper LAD, Sparano J, Lu J  Artificial Intelligence in Oncology: Clinical Applications, Challenges, and Opportunities.  Am Soc Clin Oncol Educ Book  2026 Jun;46(3):e520716. doi:10.1200/EDBK-26-520716
  23. Masri A, Cappelli F, Davis MK, Fontana M, Garcia-Pavia P, Gillmore JD, Hanna M, Obici L, Solomon SD, Sperry BW  et al.  Rationale and Design of CARDIO-TTRansform, a Phase 3 Trial of Eplontersen in Transthyretin Amyloid Cardiomyopathy.  Circ Heart Fail  2026 Jun;19(6):e014205. doi:10.1161/CIRCHEARTFAILURE.126.014205
  24. Shah SJ  Precision Medicine Is Not Optional, It's Oxygen: Reconciling Heart Failure With Preserved Ejection Fraction Trial Results Through the Lens of Phenotypic Diversity.  Struct Heart  2026 Jun;10(6):100778. pii:100778
  25. Lu H, Kosztin A, Claggett BL, Foà A, Pabón MA, Desai AS, Jhund PS, Henderson AD, Merkely B, Lam CSP  et al.  Biomarker, Functional Status, and Quality-of-Life Trajectories Before Modes of Death in Heart Failure: Post Hoc Analysis of the FINEARTS-HF Randomized Clinical Trial.  JAMA Cardiol  2026 Jun 01;11(6):574-582. doi:10.1001/jamacardio.2026.0682
  26. Banker M, do Nascimento JSP, Shownkeen H, Chang TR, Goldenberg F, Faine B, Cella D, Schuele SU, Luo Y, Tipton E  et al.  Prophylactic Antiseizure Medication in Patients with Lobar Intracerebral Hemorrhage.  Neurocrit Care  2026 Jun;44(3):850-856. doi:10.1007/s12028-025-02423-w
  27. Kaklamanos E, Kristinsdottir K, Wittbrodt M, Li M, Pitisuttithum P, Kou W, Keswani RN, Carlson D, Etemadi M, Pandolfino JE  From Pixels to Peristalsis: Comparing Achalasia Diagnosis With Artificial Intelligence With Expert Endoscopists.  Clin Gastroenterol Hepatol  2026 Jun;24(6):1542-1549. doi:10.1016/j.cgh.2025.09.034
  28. Yaku H, Burkhoff D, Borlaug BA, Lala A, Butler J, Rich S, Shah SJ  Oral Levosimendan for the Treatment of Pulmonary Hypertension due to Heart Failure With Preserved Ejection Fraction: Rationale and Design of the LEVEL Trial.  J Card Fail  2026 Jun;32(6):1059-1071. doi:10.1016/j.cardfail.2025.06.009
  29. Akerele AT, Hampton G, Kim J, Jaworski J, Lewis TJ, Khan A, Rasmussen-Torvik LJ, Luo Y, Jasper EA, Hellwege JN  et al.  Genetically-predicted placental gene expression links to uterine fibroids and endometriosis.  Placenta  2026 May 22;179:14-22. doi:10.1016/j.placenta.2026.03.023
  30. Perronne L, Gennaro N, Kobus Z, Seo M, Borhani AA, Kelahan L, Savas H, Avery R, Subedi K, Krumpelman C  et al.  A Predictive MRI Radiomics Model for Histologic Differentiation in Soft Tissue Sarcomas.  Cancers (Basel)  2026 May 21;18(10). pii:1667
  31. Singla A, Park S, Pedamallu H, Chen K, Robelly B, Rebello C, Lantz C, Zhao L, LaCombe R, Sinha R  et al.  Diagnostic Performance and Resource Utilization of Combining Blood Gene Expression, Cell-Free DNA, and Urine Chemokines for Monitoring Kidney Rejection.  Clin J Am Soc Nephrol  2026 May 21;. doi:10.2215/CJN.0000001075
  32. Chakrabarty RP, Van Vranken JG, Aoi Y, Poor TA, McElroy GS, Vasan K, Soliman SHA, Iwanaszko M, Grant RA, Howard BC  et al.  Mitochondrial L-2-hydroxyglutarate is a physiological signalling metabolite.  Nature  2026 May 20;. doi:10.1038/s41586-026-10564-x
  33. Henderson AD, Docherty KF, Talebi A, Kondo T, Petrie MC, Claggett BL, Desai AS, Vaduganathan M, Atherton JJ, Bauersachs J  et al.  A Bayesian analysis of finerenone in heart failure with mildly reduced and preserved ejection fraction: a pre-specified analysis of FINEARTS-HF.  Eur Heart J Cardiovasc Pharmacother  2026 May 19;12(3):176-185. doi:10.1093/ehjcvp/pvag010
  34. Makuvire TT, Lam CSP, Pabon MA, Claggett BL, Kulac IJ, Desai AS, Jhund PS, Henderson AD, Amarante F, Chen M  et al.  Geographic Variation in Heart Failure With Mildly Reduced or Preserved Ejection Fraction: Insights From the FINEARTS-HF Trial.  JACC Heart Fail  2026 May 15;:103105. doi:10.1016/j.jchf.2026.103105
  35. Helseth R, Claggett BL, Bhatt A, Vardeny O, Lu H, Desai AS, Jhund PS, Henderson A, Lam CSP, Senni M  et al.  Viral respiratory tract infections in heart failure: the FINEARTS-HF trial.  Eur Heart J  2026 May 11;. pii:ehag384
  36. Hamatani Y, Claggett BL, Kulac IJ, Desai AS, Jhund PS, Henderson AD, Lam CSP, Senni M, Shah SJ, Voors AA  et al.  Finerenone, polypharmacy, and clinical outcomes in heart failure: pre-specified analysis from the FINEARTS-HF trial.  Eur J Heart Fail  2026 May 11;28(2):194-203. doi:10.1093/ejhf/xuag030
  37. Khan SS, Lloyd-Jones D, Pagidipati NJ, Shah SJ, Pawlowski C, Hogan L, Williams J, Leopold J  HFpEF Explained - Living with HFpEF.  N Engl J Med  2026 May 07;394(18):e35. doi:10.1056/NEJMp2516849
  38. Hafer N, Cielo K, Duguid P, Dunn M, Gholami M, Holmes K, Hunt J, Kane C, Moussatche P, Navarro C  et al.  Crowdsourced educational resource to distinguish Translational Science (TS) from Translational Research (TR).  J Clin Transl Sci  2026;10(1):e87. pii:e87
  39. Fejzo M, Wang X, Tan Q, Zöllner J, Pujol-Gualdo N, Laisk T, , Finer S, van Heel DA,   et al.  Publisher Correction: Multi-ancestry genome-wide association study of severe pregnancy nausea and vomiting.  Nat Genet  2026 May;58(5):1186. doi:10.1038/s41588-026-02608-9
  40. Marrero N, Jha K, Grant JK, Razavi AC, Budoff MJ, Shah SJ, Rotter JI, Blumenthal RS, Post WS, Gulati M  et al.  Sex-Specific Prognostic Value of Aortic Valve Calcium and the Risk for Aortic Stenosis: Multi-Ethnic Study of Atherosclerosis (MESA).  Circ Cardiovasc Imaging  2026 May;19(5):e018849. doi:10.1161/CIRCIMAGING.125.018849
  41. Peters AE, Ahmad FS, Martyn T, Grogan M, Hanna M, Maurer MS, Goyal P  Screening Strategies for Identification of Transthyretin Amyloid Cardiomyopathy.  JACC Heart Fail  2026 May;14(5):103018. doi:10.1016/j.jchf.2026.103018
  42. Michelson KN, Hayes A, Barrera L, James K, Miller C, Guzman Z, Torres N, McNicholas A, Becker AB  Pilot Study of a Bereavement Referral Program for Parents Following Perinatal Death.  J Pain Symptom Manage  2026 May;71(5):581-591.e3. doi:10.1016/j.jpainsymman.2026.01.004
  43. Kremer N, Polo-Silveira L, Bajaj S, Sattler S, Halpern AC, Bagci U, Dusza SW, Kose K, Weber J, D'Alessandro B  et al.  Comparing dermatologists' and artificial intelligence heat maps in dermoscopic image analysis via eye tracking.  J Am Acad Dermatol  2026 May;94(5):1461-1468. doi:10.1016/j.jaad.2025.12.104
  44. Owen AL, Langshur S, Doblin BH, Vargas MC, Hinami K, Kho AN, Liss DT, O'Brien MJ  Correlates of Diagnostic Codes for Documenting Housing Instability: A Citywide Cohort Study.  Am J Prev Med  2026 May;70(5):108214. doi:10.1016/j.amepre.2025.108214
  45. Mc Causland FR, Chatur S, Vaduganathan M, Claggett BL, Kulac IJ, Desai AS, Jhund PS, Henderson AD, Rohwedder K, Amarante F  et al.  Finerenone and Cardiovascular Outcomes According to Baseline Kidney Function in Patients With Heart Failure: The FINEARTS-HF Trial.  JACC Heart Fail  2026 May;14(5):102778. doi:10.1016/j.jchf.2025.102778
  46. Shah SJ, Khan S, Lloyd-Jones D, Pagidipati NJ, Pawlowski C, Kirk K, Hogan L, Williams J, Leopold J  HFpEF Explained - Managing HFpEF in Primary Care.  N Engl J Med  2026 Apr 30;394(17):e32. doi:10.1056/NEJMp2516848
  47. Hong SS, Utz Z, Hosseini M, Zanchettin C, Tejedor Navarro H, Holmes K, Wetterstrand KA, Bates SA, Nunes Amaral LA, Donohue CR  et al.  A digital archive reveals how a funding agency cooperated with academics to support the nascent field of genomics.  Nat Commun  2026 Apr 29;17(1). pii:3621
  48. Mohamedali A, Chaudhury AS, Rivera AS, Zhou X, Stein JD, Andrews CA, Li Y, Marwah S, Shah R, Kanwar K  et al.  Linking multicenter electronic health records with socioeconomic data to examine receipt of standard versus premium intraocular lenses.  AJO Int  2026 Apr 28;3(1). pii:100209
  49. Amagai S, Powell EC, Alpern ER, Florin TA, Li Y, Liebovitz D, Luo Y, Espinoza J, Wong AF, Ramgopal S  Performance of Open-Source LLMs in Identifying Pediatric Pneumonia From Free-Text Chest Radiograph Reports.  Pediatr Emerg Care  2026 Apr 21;. doi:10.1097/PEC.0000000000003616
  50. Luo Y  Cardiovascular Endpoint Adjudication in Clinical Trials: A Proactive and Collaborative AI Approach.  J Am Coll Cardiol  2026 Apr 21;87(15):1870-1872. doi:10.1016/j.jacc.2025.12.040

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