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Northwestern University Feinberg School of Medicine
Institute for Artificial Intelligence in Medicine

Publications

Browse the list below to see the latest scientific publications stemming from our institute faculty’s work. To view publications of specific AI faculty, please visit Membership and select a profile link.

  1. Peng L, Perronne L, Gennaro N, Rashidi AP, Kobus Z, Seo M, Borhani AA, Kelahan L, Subedi K, Savas H  et al.  Performance of deep learning-based segmentation of soft tissue sarcoma by MRI sequence, tumor type and location.  Skeletal Radiol  2026 Jul;55(7):1539-1548. doi:10.1007/s00256-026-05178-3
  2. Lewis ACF, Clayton EW, Bangash H, Bland HT, Bonini KE, Cimino JJ, Connolly JJ, Freimuth RR, Fullerton SM, Hakonarson H  et al.  Navigating data sharing in research.  Am J Hum Genet  2026 Jun 04;113(6):1159-1167. doi:10.1016/j.ajhg.2026.04.004
  3. Foà A, Pabon MA, Filippatos G, Claggett BL, Miao ZM, Jhund PS, Henderson A, Brinker M, Lage A, Hofmeister L  et al.  Effects of Finerenone on Sudden Death Across the Cardio-Kidney-Metabolic Landscape: A FINE-HEART Analysis.  J Am Coll Cardiol  2026 Jun 03;. pii:S0735-1097(26)06417-X
  4. Parkinson G, Patel R, Bergstrom C, Vadasz B, Amgad M, Cooper LAD, Sparano J, Lu J  Artificial Intelligence in Oncology: Clinical Applications, Challenges, and Opportunities.  Am Soc Clin Oncol Educ Book  2026 Jun;46(3):e520716. doi:10.1200/EDBK-26-520716
  5. Shah SJ  Precision Medicine Is Not Optional, It's Oxygen: Reconciling Heart Failure With Preserved Ejection Fraction Trial Results Through the Lens of Phenotypic Diversity.  Struct Heart  2026 Jun;10(6):100778. pii:100778
  6. Kaklamanos E, Kristinsdottir K, Wittbrodt M, Li M, Pitisuttithum P, Kou W, Keswani RN, Carlson D, Etemadi M, Pandolfino JE  From Pixels to Peristalsis: Comparing Achalasia Diagnosis With Artificial Intelligence With Expert Endoscopists.  Clin Gastroenterol Hepatol  2026 Jun;24(6):1542-1549. doi:10.1016/j.cgh.2025.09.034
  7. Sharma A, Nateghi R, Ayad M, Cooper LAD, Goldstein JA  Machine learning identification of maternal inflammatory response and systemic inflammatory response from placental membrane whole slide images.  Placenta  2026 May 22;181:204-210. doi:10.1016/j.placenta.2026.05.028
  8. Akerele AT, Hampton G, Kim J, Jaworski J, Lewis TJ, Khan A, Rasmussen-Torvik LJ, Luo Y, Jasper EA, Hellwege JN  et al.  Genetically-predicted placental gene expression links to uterine fibroids and endometriosis.  Placenta  2026 May 22;179:14-22. doi:10.1016/j.placenta.2026.03.023
  9. Perronne L, Gennaro N, Kobus Z, Seo M, Borhani AA, Kelahan L, Savas H, Avery R, Subedi K, Krumpelman C  et al.  A Predictive MRI Radiomics Model for Histologic Differentiation in Soft Tissue Sarcomas.  Cancers (Basel)  2026 May 21;18(10). pii:1667
  10. Singla A, Park S, Pedamallu H, Chen K, Robelly B, Rebello C, Lantz C, Zhao L, LaCombe R, Sinha R  et al.  Diagnostic Performance and Resource Utilization of Combining Blood Gene Expression, Cell-Free DNA, and Urine Chemokines for Monitoring Kidney Rejection.  Clin J Am Soc Nephrol  2026 May 21;. doi:10.2215/CJN.0000001075
  11. Chakrabarty RP, Van Vranken JG, Aoi Y, Poor TA, McElroy GS, Vasan K, Soliman SHA, Iwanaszko M, Grant RA, Howard BC  et al.  Mitochondrial L-2-hydroxyglutarate is a physiological signalling metabolite.  Nature  2026 May 20;. doi:10.1038/s41586-026-10564-x
  12. Henderson AD, Docherty KF, Talebi A, Kondo T, Petrie MC, Claggett BL, Desai AS, Vaduganathan M, Atherton JJ, Bauersachs J  et al.  A Bayesian analysis of finerenone in heart failure with mildly reduced and preserved ejection fraction: a pre-specified analysis of FINEARTS-HF.  Eur Heart J Cardiovasc Pharmacother  2026 May 19;12(3):176-185. doi:10.1093/ehjcvp/pvag010
  13. Makuvire TT, Lam CSP, Pabon MA, Claggett BL, Kulac IJ, Desai AS, Jhund PS, Henderson AD, Amarante F, Chen M  et al.  Geographic Variation in Heart Failure With Mildly Reduced or Preserved Ejection Fraction: Insights From the FINEARTS-HF Trial.  JACC Heart Fail  2026 May 15;:103105. doi:10.1016/j.jchf.2026.103105
  14. Helseth R, Claggett BL, Bhatt A, Vardeny O, Lu H, Desai AS, Jhund PS, Henderson A, Lam CSP, Senni M  et al.  Viral respiratory tract infections in heart failure: the FINEARTS-HF trial.  Eur Heart J  2026 May 11;. pii:ehag384
  15. Hamatani Y, Claggett BL, Kulac IJ, Desai AS, Jhund PS, Henderson AD, Lam CSP, Senni M, Shah SJ, Voors AA  et al.  Finerenone, polypharmacy, and clinical outcomes in heart failure: pre-specified analysis from the FINEARTS-HF trial.  Eur J Heart Fail  2026 May 11;28(2):194-203. doi:10.1093/ejhf/xuag030
  16. Masri A, Cappelli F, Davis MK, Fontana M, Garcia-Pavia P, Gillmore JD, Hanna M, Obici L, Solomon SD, Sperry BW  et al.  Rationale and Design of CARDIO-TTRansform, a Phase 3 Trial of Eplontersen in Transthyretin Amyloid Cardiomyopathy.  Circ Heart Fail  2026 May 09;:e014205. doi:10.1161/CIRCHEARTFAILURE.126.014205
  17. Khan SS, Lloyd-Jones D, Pagidipati NJ, Shah SJ, Pawlowski C, Hogan L, Williams J, Leopold J  HFpEF Explained - Living with HFpEF.  N Engl J Med  2026 May 07;394(18):e35. doi:10.1056/NEJMp2516849
  18. Hafer N, Cielo K, Duguid P, Dunn M, Gholami M, Holmes K, Hunt J, Kane C, Moussatche P, Navarro C  et al.  Crowdsourced educational resource to distinguish Translational Science (TS) from Translational Research (TR).  J Clin Transl Sci  2026;10(1):e87. pii:e87
  19. Fejzo M, Wang X, Tan Q, Zöllner J, Pujol-Gualdo N, Laisk T, , Finer S, van Heel DA,   et al.  Publisher Correction: Multi-ancestry genome-wide association study of severe pregnancy nausea and vomiting.  Nat Genet  2026 May;58(5):1186. doi:10.1038/s41588-026-02608-9
  20. Marrero N, Jha K, Grant JK, Razavi AC, Budoff MJ, Shah SJ, Rotter JI, Blumenthal RS, Post WS, Gulati M  et al.  Sex-Specific Prognostic Value of Aortic Valve Calcium and the Risk for Aortic Stenosis: Multi-Ethnic Study of Atherosclerosis (MESA).  Circ Cardiovasc Imaging  2026 May;19(5):e018849. doi:10.1161/CIRCIMAGING.125.018849
  21. Peters AE, Ahmad FS, Martyn T, Grogan M, Hanna M, Maurer MS, Goyal P  Screening Strategies for Identification of Transthyretin Amyloid Cardiomyopathy.  JACC Heart Fail  2026 May;14(5):103018. doi:10.1016/j.jchf.2026.103018
  22. Michelson KN, Hayes A, Barrera L, James K, Miller C, Guzman Z, Torres N, McNicholas A, Becker AB  Pilot Study of a Bereavement Referral Program for Parents Following Perinatal Death.  J Pain Symptom Manage  2026 May;71(5):581-591.e3. doi:10.1016/j.jpainsymman.2026.01.004
  23. Kremer N, Polo-Silveira L, Bajaj S, Sattler S, Halpern AC, Bagci U, Dusza SW, Kose K, Weber J, D'Alessandro B  et al.  Comparing dermatologists' and artificial intelligence heat maps in dermoscopic image analysis via eye tracking.  J Am Acad Dermatol  2026 May;94(5):1461-1468. doi:10.1016/j.jaad.2025.12.104
  24. Owen AL, Langshur S, Doblin BH, Vargas MC, Hinami K, Kho AN, Liss DT, O'Brien MJ  Correlates of Diagnostic Codes for Documenting Housing Instability: A Citywide Cohort Study.  Am J Prev Med  2026 May;70(5):108214. doi:10.1016/j.amepre.2025.108214
  25. Mc Causland FR, Chatur S, Vaduganathan M, Claggett BL, Kulac IJ, Desai AS, Jhund PS, Henderson AD, Rohwedder K, Amarante F  et al.  Finerenone and Cardiovascular Outcomes According to Baseline Kidney Function in Patients With Heart Failure: The FINEARTS-HF Trial.  JACC Heart Fail  2026 May;14(5):102778. doi:10.1016/j.jchf.2025.102778
  26. Shah SJ, Khan S, Lloyd-Jones D, Pagidipati NJ, Pawlowski C, Kirk K, Hogan L, Williams J, Leopold J  HFpEF Explained - Managing HFpEF in Primary Care.  N Engl J Med  2026 Apr 30;394(17):e32. doi:10.1056/NEJMp2516848
  27. Hong SS, Utz Z, Hosseini M, Zanchettin C, Tejedor Navarro H, Holmes K, Wetterstrand KA, Bates SA, Nunes Amaral LA, Donohue CR  et al.  A digital archive reveals how a funding agency cooperated with academics to support the nascent field of genomics.  Nat Commun  2026 Apr 29;17(1). pii:3621
  28. Mohamedali A, Chaudhury AS, Rivera AS, Zhou X, Stein JD, Andrews CA, Li Y, Marwah S, Shah R, Kanwar K  et al.  Linking multicenter electronic health records with socioeconomic data to examine receipt of standard versus premium intraocular lenses.  AJO Int  2026 Apr 28;3(1). pii:100209
  29. Amagai S, Powell EC, Alpern ER, Florin TA, Li Y, Liebovitz D, Luo Y, Espinoza J, Wong AF, Ramgopal S  Performance of Open-Source LLMs in Identifying Pediatric Pneumonia From Free-Text Chest Radiograph Reports.  Pediatr Emerg Care  2026 Apr 21;. doi:10.1097/PEC.0000000000003616
  30. Luo Y  Cardiovascular Endpoint Adjudication in Clinical Trials: A Proactive and Collaborative AI Approach.  J Am Coll Cardiol  2026 Apr 21;87(15):1870-1872. doi:10.1016/j.jacc.2025.12.040
  31. Oshinubi K, Chen Y, Doerry E, Gel ES, Hepp C, Lant T, Mehrotra S, Sabo S, Mihaljevic J  A systematic review of spatial epidemiological modeling approaches applied during the COVID-19 pandemic.  BMC Public Health  2026 Apr 15;26(1). pii:1691
  32. Hosseini M, Earp BD, Porsdam Mann S, Holmes K  Generative AI can and should accelerate research evaluation reform to better recognize 'distinctly human contributions'.  Res Eval  2026;35:rvag020. pii:rvag020
  33. Hamatani Y, Ostrominski JW, Lu H, Claggett BL, Miao ZM, Desai AS, Jhund PS, Henderson AD, Lam CSP, Senni M  et al.  Effects of Finerenone Across a Range of Heart Failure Duration: A Prespecified Analysis of the FINEARTS-HF Trial.  Eur J Heart Fail  2026 Apr 08;. pii:xuag119
  34. Olson EM, Cohen ER, Cheema YR, Bockrath R, O'Brien CL, Whitlow GA, Hufmeyer K, Sanguino SM, Green MM, Garcia PM  et al.  Impact of Livestreaming Pre-Clerkship Lectures: A Prospective Pilot with Multiyear Follow-up.  Med Sci Educ  2026 Apr;36(2):755-763. doi:10.1007/s40670-025-02629-9
  35. Hosseini M, Kerridge S, Allen L, Kiermer V, Holmes K  Enhancing, Understanding and Adoption of the Contributor Roles Taxonomy (CRediT).  Learn Publ  2026 Apr;39(2). pii:e2048
  36. Cohen A, Michelson KN, Macy ML, Heard-Garris N, Kan K  The Association Between Shared Decision-Making and Child Health in the General Pediatric Population.  Matern Child Health J  2026 Apr;30(4):575-583. doi:10.1007/s10995-026-04251-6
  37. Fejzo M, Wang X, Tan Q, Zöllner J, Pujol-Gualdo N, Laisk T, , Finer S, van Heel DA,   et al.  Multi-ancestry genome-wide association study of severe pregnancy nausea and vomiting.  Nat Genet  2026 Apr;58(4):810-820. doi:10.1038/s41588-026-02564-4
  38. Aneja A, Culler KL, Ding J, Taylor KD, Shah SJ, Rasmussen-Torvik L, Patel RB  Associations of the ICAM1 p.K56M HFpEF Risk Variant With Pericardial Adiposity and the Inflammatory Proteome.  Circ Genom Precis Med  2026 Apr;19(2):e005475. doi:10.1161/CIRCGEN.125.005475
  39. Lei Y, Zhou T, Zhang B, Zhang D, Tang H, Chen J, Wu Q, Li L, Bailey LC, Becich MJ  et al.  Post-Acute Dyslipidemia and Abnormal Body Mass Index in Children and Adolescents with COVID-19: A Cohort Study from the RECOVER Initiative.  J Pediatr  2026 Apr;291:114996. doi:10.1016/j.jpeds.2026.114996
  40. Foà A, Vaduganathan M, Claggett BL, Desai AS, Jhund PS, Henderson AD, Chatur S, Amarante F, Hofmeister L, Horvat-Broecker A  et al.  Finerenone-Related Risk of Hypotension in Heart Failure With Mildly Reduced or Preserved Ejection Fraction.  JACC Heart Fail  2026 Apr;14(4):102779. doi:10.1016/j.jchf.2025.102779
  41. Lu H, Kosztin A, Claggett BL, Foà A, Pabón MA, Desai AS, Jhund PS, Henderson AD, Merkely B, Lam CSP  et al.  Biomarker, Functional Status, and Quality-of-Life Trajectories Before Modes of Death in Heart Failure: Post Hoc Analysis of the FINEARTS-HF Randomized Clinical Trial.  JAMA Cardiol  2026 Mar 28;. pii:e260682
  42. Mehrotra S, Barah M, Kilambi V, Formica RN  A Sliding Scale AdaptiVe Expedited rescue algorithm for deceased donor kidney transplantation.  Am J Transplant  2026 Mar 26;. pii:S1600-6135(26)00168-1
  43. Wang K, Wang J, Feng R, Dudnyk K, Kim YJ, Lim JYS, Lee M, Zhang Y, Gao X, Cheng Y  et al.  Silencing of BCL11A by disrupting enhancer-dependent epigenetic insulation.  Blood  2026 Mar 26;147(13):1470-1484. doi:10.1182/blood.2025030211
  44. Schnauss M, Handa N, Nateghi R, Alam R, Jang JW, Huang MM, Abrams A, Neill C, Kumar SKSR, Hubbard N  et al.  Clinical and Reader Associated Correlates of Clinically Significant Magnetic Resonance Imaging-Invisible Prostate Cancer Based on Negative Magnetic Resonance Imaging.  J Urol  2026 Mar 23;:101097JU0000000000005028. doi:10.1097/JU.0000000000005028
  45. Nateghi R, Sun A, Dang H, Handa N, Schnauss M, Michael J, Jang JW, Nezami BG, Saft M, Neill C  et al.  Prediction of molecular subtypes from histology: AI-driven analysis of prostate cancer morphological patterns and therapeutic implications.  NPJ Precis Oncol  2026 Mar 19;. doi:10.1038/s41698-026-01335-y
  46. Hamatani Y, Peikert A, Claggett BL, Desai AS, Jhund PS, Henderson AD, Lam CSP, Senni M, Shah SJ, Voors AA  et al.  Finerenone and Quality of Life in Heart Failure: Component-Level Analyses and Clinical Relevance of the Kansas City Cardiomyopathy Questionnaire.  Eur J Heart Fail  2026 Mar 12;. pii:xuag062
  47. Desai AS, Pandey A, Suratekar R, Ahmad FS, Alger HM, Anto AG, Nujum G S, Lopez-Jimenez F, Oh JK, Asfahan S  et al.  Predicting Heart Failure From 12-Lead ECGs Using AI: A HeartShare/AMP-HF Pooled Cohort Analysis.  J Am Coll Cardiol  2026 Mar 03;87(8):990-1005. doi:10.1016/j.jacc.2025.10.065
  48. Liu TX, Nedadur R, Ahmad FS, Baldridge AS, Thomas JD, Kline AS, Shah S, Narang A, Johnston DR, McCarthy PM  Artificial Intelligence Identification of Heart Failure With Preserved Ejection Fraction Substrate in Cardiac Surgery Patients.  Ann Thorac Surg Short Rep  2026 Mar;4(1):80-86. doi:10.1016/j.atssr.2025.07.027
  49. Gutstein DB, Iorga M, Stocks J, Gill N, Sleeman J, Gefen TD, Los M, Nelson C, Geula C, Weintraub S  et al.  Identifying neuropathologic disease in primary progressive aphasia using narrative speech.  Alzheimers Dement  2026 Mar;22(3):e71294. pii:e71294
  50. Motelow JE, Malakar A, Krishna Murthy SB, Verbitsky M, Kahn A, Estrella E, Shao W, Kunkel L, Wiesenhahn M, Beckett J  et al.  Interstitial cystitis: a phenotype and rare variant exome sequencing study.  EBioMedicine  2026 Mar;125:106150. pii:106150

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