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Northwestern University Feinberg School of Medicine
Institute for Artificial Intelligence in Medicine

Publications

Browse the list below to see the latest scientific publications stemming from our institute faculty’s work. To view publications of specific AI faculty, please visit Membership and select a profile link.

  1. Gao J, Giro P, Delaney JA, Rasmussen-Torvik L, Taylor KD, Thorp EB, Doyle MF, Feinstein MJ, Sitlani CM, Olson N  et al.  Immune cell profiling of the ICAM1 p.K56M heart failure with preserved ejection fraction risk variant.  ESC Heart Fail  2024 Jul 22;. doi:10.1002/ehf2.14983
  2. Shimbo D, Shah RU, Abdalla M, Agarwal R, Ahmad FS, Anaya G, Attia ZI, Bull S, Chang AR, Commodore-Mensah Y  et al.  Transforming Hypertension Diagnosis and Management in The Era of Artificial Intelligence: A 2023 National Heart, Lung, and Blood Institute (NHLBI) Workshop Report.  Hypertension  2024 Jul 16;. doi:10.1161/HYPERTENSIONAHA.124.22095
  3. Schou M, Petrie MC, Borlaug BA, Butler J, Davies MJ, Kitzman DW, Shah SJ, Verma S, Patel S, Chinnakondepalli KM  et al.  Semaglutide and NYHA Functional Class in Obesity-Related Heart Failure With Preserved Ejection Fraction: The STEP-HFpEF Program.  J Am Coll Cardiol  2024 Jul 16;84(3):247-257. doi:10.1016/j.jacc.2024.04.038
  4. Doiron JE, Xia H, Yu X, Nevins AR, LaPenna KB, Sharp TE, Goodchild TT, Allerton TD, Elgazzaz M, Lazartigues E  et al.  Adjunctive therapy with an oral H2S donor provides additional therapeutic benefit beyond SGLT2 inhibition in cardiometabolic heart failure with preserved ejection fraction.  Br J Pharmacol  2024 Jul 09;. doi:10.1111/bph.16493
  5. Simon GE, Moise N, Mohr DC  Management of Depression in Adults: A Review.  JAMA  2024 Jul 09;332(2):141-152. doi:10.1001/jama.2024.5756
  6. Zhang D, Stein R, Lu Y, Zhou T, Lei Y, Li L, Chen J, Arnold J, Becich MJ, Chrischilles EA  et al.  Pediatric Gastrointestinal Outcomes During the Post-Acute Phase of COVID-19: Findings from RECOVER Initiative from 29 Hospitals in the US.  medRxiv  2024 Jul 09;. pii:2024.05.21.24307699
  7. Maimone C, Dolan BM, Green MM, Sanguino SM, O'Brien CL  Using Natural Language Processing to Visualize Narrative Feedback in a Medical Student Performance Dashboard.  Acad Med  2024 Jul 03;. doi:10.1097/ACM.0000000000005800
  8. Wittbrodt M, Klug M, Etemadi M, Yang A, Pandolfino JE, Keswani RN  Assessment of colonoscopy skill using machine learning to measure quality: Proof-of-concept and initial validation.  Endosc Int Open  2024 Jul;12(7):E849-E853. doi:10.1055/a-2333-8138
  9. Petrie MC, Borlaug BA, Butler J, Davies MJ, Kitzman DW, Shah SJ, Verma S, Jensen TJ, Einfeldt MN, Liisberg K  et al.  Semaglutide and NT-proBNP in Obesity-Related HFpEF: Insights From the STEP-HFpEF Program.  J Am Coll Cardiol  2024 Jul 02;84(1):27-40. doi:10.1016/j.jacc.2024.04.022
  10. Abdollahi A, Kato Y, Bakhshi H, Varadarajan V, Chehab O, Zeitoun R, Ostovaneh MR, Wu CO, Bertoni AG, Shah SJ  et al.  Differential Stroke Volume between Left and Right Ventricles as a Predictor of Clinical Outcomes: The MESA Study.  Radiology  2024 Jul;312(1):e232973. doi:10.1148/radiol.232973
  11. Luo Y, Mao C, Sanchez-Pinto LN, Ahmad FS, Naidech A, Rasmussen L, Pacheco JA, Schneider D, Mithal LB, Dresden S  et al.  Northwestern University resource and education development initiatives to advance collaborative artificial intelligence across the learning health system.  Learn Health Syst  2024 Jul;8(3):e10417. pii:e10417
  12. Patel RB, Shah SJ  Left Atrial Myopathy in Heart Failure With Preserved Ejection: Don't Raise the Roof!  Circ Cardiovasc Imaging  2024 Jul;17(7):e017137. doi:10.1161/CIRCIMAGING.124.017137
  13. Jani VP, Strom JB, Gami A, Beussink-Nelson L, Patel R, Michos ED, Shah SJ, Freed BH, Mukherjee M  Optimal Method for Assessing Right Ventricular to Pulmonary Arterial Coupling in Older Healthy Adults: The Multi-Ethnic Study of Atherosclerosis.  Am J Cardiol  2024 Jul 01;222:11-19. doi:10.1016/j.amjcard.2024.03.043
  14. Fudim M, Litwin SE, Borlaug BA, Mohan RC, Price MJ, Fail P, Zirakashvili T, Shaburishvili T, Goyal P, Hummel SL  et al.  Endovascular Ablation of the Right Greater Splanchnic Nerve in Heart Failure With Preserved Ejection Fraction: Rationale, Design and Lead-in Phase Results of the REBALANCE-HF Trial.  J Card Fail  2024 Jul;30(7):877-889. doi:10.1016/j.cardfail.2023.12.010
  15. Shah KP, Khan SS, Baldridge AS, Grady KL, Cella D, Goyal P, Allen LA, Smith JD, Lagu TC, Ahmad FS  Health Status in Heart Failure and Cancer: Analysis of the Medicare Health Outcomes Survey 2016-2020.  JACC Heart Fail  2024 Jul;12(7):1166-1178. doi:10.1016/j.jchf.2023.10.003
  16. Kitzman DW, Lewis GD, Pandey A, Borlaug BA, Sauer AJ, Litwin SE, Sharma K, Jorkasky DK, Khan S, Shah SJ  A novel controlled metabolic accelerator for the treatment of obesity-related heart failure with preserved ejection fraction: Rationale and design of the Phase 2a HuMAIN trial.  Eur J Heart Fail  2024 Jun 26;. doi:10.1002/ejhf.3305
  17. Verma S, Butler J, Borlaug BA, Davies M, Kitzman DW, Shah SJ, Petrie MC, Barros E, Rönnbäck C, Vestergaard LS  et al.  Efficacy of Semaglutide by Sex in Obesity-Related Heart Failure With Preserved Ejection Fraction: STEP-HFpEF Trials.  J Am Coll Cardiol  2024 Jun 19;. pii:S0735-1097(24)07445-X
  18. Gustafsson F, Petrie MC, Komtebedde J, Swarup V, Winkler S, Hasenfuß G, Borlaug BA, Mohan RC, Flaherty JD, Sverdlov AL  et al.  2-Year Outcomes of an Atrial Shunt Device in HFpEF/HFmrEF: Results From REDUCE LAP-HF II.  JACC Heart Fail  2024 Jun 13;. pii:S2213-1779(24)00331-7
  19. Kondo T, Campbell R, Jhund PS, Anand IS, Carson PE, Lam CSP, Shah SJ, Vaduganathan M, Zannad F, Zile MR  et al.  Low Natriuretic Peptide Levels and Outcomes in Patients With Heart Failure and Preserved Ejection Fraction.  JACC Heart Fail  2024 Jun 06;. pii:S2213-1779(24)00414-1
  20. Edmonston D, Lydon E, Mulder H, Chiswell K, Lampron Z, Marsolo K, Goss A, Ayoub I, Shah RC, Chang AR  et al.  Concordance With Screening and Treatment Guidelines for Chronic Kidney Disease in Type 2 Diabetes.  JAMA Netw Open  2024 Jun 03;7(6):e2418808. pii:e2418808
  21. Marrero N, Jha K, Razavi AC, Boakye E, Anchouche K, Dzaye O, Budoff MJ, Tsai MY, Shah SJ, Rotter JI  et al.  Identifying People at High Risk for Severe Aortic Stenosis: Aortic Valve Calcium Versus Lipoprotein(a) and Low-Density Lipoprotein Cholesterol.  Circ Cardiovasc Imaging  2024 Jun;17(6):e016372. doi:10.1161/CIRCIMAGING.123.016372
  22. Filipp M, Shah SJ  Proving SGLT2 Inhibitor-Mediated Improvement in Cardiomyocyte Energetics: Beyond a Reasonable Doubt?  Circ Heart Fail  2024 Jun;17(6):e011646. doi:10.1161/CIRCHEARTFAILURE.124.011646
  23. Vaduganathan M, Claggett BL, Lam CSP, Pitt B, Senni M, Shah SJ, Voors AA, Zannad F, Desai AS, Jhund PS  et al.  Finerenone in patients with heart failure with mildly reduced or preserved ejection fraction: Rationale and design of the FINEARTS-HF trial.  Eur J Heart Fail  2024 Jun;26(6):1324-1333. doi:10.1002/ejhf.3253
  24. Solomon SD, Ostrominski JW, Vaduganathan M, Claggett B, Jhund PS, Desai AS, Lam CSP, Pitt B, Senni M, Shah SJ  et al.  Baseline characteristics of patients with heart failure with mildly reduced or preserved ejection fraction: The FINEARTS-HF trial.  Eur J Heart Fail  2024 Jun;26(6):1334-1346. doi:10.1002/ejhf.3266
  25. Wang X, Yue F  Hijacked enhancer-promoter and silencer-promoter loops in cancer.  Curr Opin Genet Dev  2024 Jun;86:102199. doi:10.1016/j.gde.2024.102199
  26. Pabón MA, Wang X, Lam CSP, O'Meara E, Vaduganathan M, Claggett BL, Foà A, Lu H, Langkilde AM, De Boer RA  et al.  Sex Differences in Heart Failure With Improved Ejection Fraction: The DELIVER Trial.  JACC Heart Fail  2024 Jun;12(6):1119-1122. doi:10.1016/j.jchf.2024.03.011
  27. Selvaraj S, Patel S, Sauer AJ, McGarrah RW, Jones P, Kwee LC, Windsor SL, Ilkayeva O, Muehlbauer MJ, Newgard CB  et al.  Targeted Metabolomic Profiling of Dapagliflozin in Heart Failure With Preserved Ejection Fraction: The PRESERVED-HF Trial.  JACC Heart Fail  2024 Jun;12(6):999-1011. doi:10.1016/j.jchf.2024.02.018
  28. Patel RB, Silvestry FE, Komtebedde J, Solomon SD, Hasenfuß G, Litwin SE, Borlaug BA, Price MJ, Kawash R, Hummel SL  et al.  Atrial Shunt Device Effects on Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction: The REDUCE LAP-HF II Randomized Clinical Trial.  JAMA Cardiol  2024 Jun 01;9(6):507-522. doi:10.1001/jamacardio.2024.0520
  29. Atreya MR, Bennett TD, Geva A, Faustino EVS, Rogerson CM, Lutfi R, Cvijanovich NZ, Bigham MT, Nowak J, Schwarz AJ  et al.  Biomarker Assessment of a High-Risk, Data-Driven Pediatric Sepsis Phenotype Characterized by Persistent Hypoxemia, Encephalopathy, and Shock.  Pediatr Crit Care Med  2024 Jun 01;25(6):512-517. doi:10.1097/PCC.0000000000003499
  30. Belue MJ, Harmon SA, Yang D, An JY, Gaur S, Law YM, Turkbey E, Xu Z, Tetreault J, Lay NS  et al.  Deep Learning-Based Detection and Classification of Bone Lesions on Staging Computed Tomography in Prostate Cancer: A Development Study.  Acad Radiol  2024 Jun;31(6):2424-2433. doi:10.1016/j.acra.2024.01.009
  31. Castaño A, Heitner SB, Masri A, Huda A, Calambur V, Bruno M, Schumacher J, Emir B, Isherwood C, Shah SJ  EstimATTR: A Simplified, Machine-Learning-Based Tool to Predict the Risk of Wild-Type Transthyretin Amyloid Cardiomyopathy.  J Card Fail  2024 Jun;30(6):778-787. doi:10.1016/j.cardfail.2023.11.017
  32. Mihaljevic JR, Chief C, Malik M, Oshinubi K, Doerry E, Gel E, Hepp C, Lant T, Mehrotra S, Sabo S  An inaugural forum on epidemiological modeling for public health stakeholders in Arizona.  Front Public Health  2024;12:1357908. pii:1357908
  33. Ye J, Woods D, Jordan N, Starren J  The role of artificial intelligence for the application of integrating electronic health records and patient-generated data in clinical decision support.  AMIA Jt Summits Transl Sci Proc  2024;2024:459-467
  34. Ladner DP, Manski CF, Mehrotra S  New Liver Allocation Policy and National Liver Transplant Volume.  JAMA Surg  2024 May 29;. doi:10.1001/jamasurg.2024.1209
  35. Lassen MCH, Ostrominski JW, Inzucchi SE, Claggett BL, Kulac I, Jhund P, de Boer RA, Hernandez AF, Kosiborod MN, Lam CSP  et al.  Effect of dapagliflozin in patients with diabetes and heart failure with mildly reduced or preserved ejection fraction according to background glucose-lowering therapy: A pre-specified analysis of the DELIVER trial.  Eur J Heart Fail  2024 Jul;26(7):1539-1548. doi:10.1002/ejhf.3269
  36. Shah SJ, Sharma K, Borlaug BA, Butler J, Davies M, Kitzman DW, Petrie MC, Verma S, Patel S, Chinnakondepalli KM  et al.  Semaglutide and Diuretic Use in Obesity-Related Heart Failure with Preserved Ejection Fraction: A Pooled Analysis of the STEP-HFpEF and STEP-HFpEF-DM trials.  Eur Heart J  2024 May 13;. pii:ehae322
  37. Ostrominski JW, Aggarwal R, Claggett BL, Kulac IJ, Desai AS, Jhund PS, Lam CSP, Pitt B, Senni M, Shah SJ  et al.  Generalizability of the Spectrum of Kidney Risk in the FINEARTS-HF Trial to U.S. Adults With Heart Failure.  J Card Fail  2024 May 11;. pii:S1071-9164(24)00156-8
  38. Ashworth RC, Malone JR, Franklin D, Sorce LR, Clayman ML, Frader J, White DB, Michelson KN  Associations of Patient and Parent Characteristics With Parental Decision Regret in the PICU: A Secondary Analysis of the 2015-2017 Navigate Randomized Comparative Trial.  Pediatr Crit Care Med  2024 May 10;. doi:10.1097/PCC.0000000000003534
  39. Waypa GB, Smith KA, Mungai PT, Dudley VJ, Helmin KA, Singer BD, Peek CB, Bass J, Nelson L, Shah SJ  et al.  Mitochondria regulate proliferation in adult cardiac myocytes.  J Clin Invest  2024 May 09;134(13). pii:e165482
  40. Mukherjee M, Strom JB, Afilalo J, Hu M, Beussink-Nelson L, Kim J, Addetia K, Bertoni AG, Gottdiener JS, Michos ED  et al.  Normative Values of Echocardiographic Chamber Size and Function in Older Healthy Adults: The Multi-Ethnic Study of Atherosclerosis.  Circ Cardiovasc Imaging  2024 May;17(5):e016420. doi:10.1161/CIRCIMAGING.123.016420
  41. Bramante CT, Beckman KB, Mehta T, Karger AB, Odde DJ, Tignanelli CJ, Buse JB, Johnson DM, Watson RHB, Daniel JJ  et al.  Favorable Antiviral Effect of Metformin on Severe Acute Respiratory Syndrome Coronavirus 2 Viral Load in a Randomized, Placebo-Controlled Clinical Trial of Coronavirus Disease 2019.  Clin Infect Dis  2024 May 01;. pii:ciae159
  42. Kiraly AP, Cunningham CA, Najafi R, Nabulsi Z, Yang J, Lau C, Ledsam JR, Ye W, Ardila D, McKinney SM  et al.  Assistive AI in Lung Cancer Screening: A Retrospective Multinational Study in the United States and Japan.  Radiol Artif Intell  2024 May;6(3):e230079. pii:e230079
  43. Yaku H, Fudim M, Shah SJ  Role of splanchnic circulation in the pathogenesis of heart failure: State-of-the-art review.  J Cardiol  2024 May;83(5):330-337. doi:10.1016/j.jjcc.2024.02.004
  44. Lakhtakia T, Smith SR, Mohr DC, Stamatis CA  Longitudinal associations of daily affective dynamics with depression, generalized anxiety, and social anxiety symptoms.  J Affect Disord  2024 May 01;352:437-444. doi:10.1016/j.jad.2024.01.250
  45. Maning J, Shah SJ, Patel RB  With Great Data Come Great Responsibilities: The Cardiac Amyloidosis Registry Study.  J Card Fail  2024 May;30(5):679-681. doi:10.1016/j.cardfail.2023.12.016
  46. Shi Y, Lenze EJ, Mohr DC, Lee JM, Hu L, Metts CL, Fong MWM, Wong AWK  Post-stroke Depressive Symptoms and Cognitive Performances: A Network Analysis.  Arch Phys Med Rehabil  2024 May;105(5):892-900. doi:10.1016/j.apmr.2023.10.006
  47. Butler J, Shah SJ, Petrie MC, Borlaug BA, Abildstrøm SZ, Davies MJ, Hovingh GK, Kitzman DW, Møller DV, Verma S  et al.  Semaglutide versus placebo in people with obesity-related heart failure with preserved ejection fraction: a pooled analysis of the STEP-HFpEF and STEP-HFpEF DM randomised trials.  Lancet  2024 Apr 27;403(10437):1635-1648. doi:10.1016/S0140-6736(24)00469-0
  48. Smith JD, Carroll AJ, Sanuade OA, Johnson R, Abramsohn EM, Abbas H, Ahmad FS, Eggleston A, Lazar D, Lindau ST  et al.  Process of Engaging Community and Scientific Partners in the Development of the CIRCL-Chicago Study Protocol.  Ethn Dis  2023 Dec;DECIPHeR(Spec Issue):18-26. doi:10.18865/ed.DECIPHeR.18
  49. Adler DA, Stamatis CA, Meyerhoff J, Mohr DC, Wang F, Aranovich GJ, Sen S, Choudhury T  Measuring algorithmic bias to analyze the reliability of AI tools that predict depression risk using smartphone sensed-behavioral data.  Npj Ment Health Res  2024 Apr 22;3(1):17. pii:17
  50. Kosiborod MN, Petrie MC, Borlaug BA, Butler J, Davies MJ, Hovingh GK, Kitzman DW, Møller DV, Treppendahl MB, Verma S  et al.  Semaglutide in Patients with Obesity-Related Heart Failure and Type 2 Diabetes.  N Engl J Med  2024 Apr 18;390(15):1394-1407. doi:10.1056/NEJMoa2313917