Publications
Browse the list below to see the latest scientific publications stemming from our institute faculty’s work. To view publications of specific AI faculty, please visit Membership and select a profile link.
- Lyu H, Chen X, Cheng Y, Zhang T, Wang P, Wong JH, Wang J, Stasiak L, Sun L, Yang G et al. Pioneer factor GATA6 promotes colorectal cancer through 3D genome regulation. Sci Adv 2025 Feb 07;11(6):eads4985. doi:10.1126/sciadv.ads4985
- Liu H, Abedini A, Ha E, Ma Z, Sheng X, Dumoulin B, Qiu C, Aranyi T, Li S, Dittrich N et al. Kidney multiome-based genetic scorecard reveals convergent coding and regulatory variants. Science 2025 Feb 07;387(6734):eadp4753. doi:10.1126/science.adp4753
- Culler K, Zelnick LR, Mehta RC, de Sosa GR, Kansal M, Rao PS, Bhat Z, Taliercio J, Horwitz E, Chen J et al. The ICAM1 p.K56M variant and risk of heart failure in chronic kidney disease: the Chronic Renal Insufficiency Cohort study. Heart 2025 Feb 06;. pii:heartjnl-2024-325205
- Jakubek YA, Ma X, Stilp AM, Yu F, Bacon J, Wong JW, Aguet F, Ardlie K, Arnett DK, Barnes K et al. Genomic and phenotypic correlates of mosaic loss of chromosome Y in blood. Am J Hum Genet 2025 Feb 06;112(2):276-290. doi:10.1016/j.ajhg.2024.12.014
- Gundogdu B, Chatterjee A, Medved M, Bagci U, Karczmar GS, Oto A Physics-Informed Autoencoder for Prostate Tissue Microstructure Profiling with Hybrid Multidimensional MRI. Radiol Artif Intell 2025 Feb 05;:e240167. doi:10.1148/ryai.240167
- Zhang D, Stein R, Lu Y, Zhou T, Lei Y, Li L, Chen J, Arnold J, Becich MJ, Chrischilles EA et al. Pediatric Gastrointestinal Tract Outcomes During the Postacute Phase of COVID-19. JAMA Netw Open 2025 Feb 03;8(2):e2458366. doi:10.1001/jamanetworkopen.2024.58366
- Butt JH, Jhund PS, Henderson AD, Claggett BL, Desai AS, Viswanathan P, Kolkhof P, Schloemer P, Amarante F, Lam CSP et al. Finerenone and new-onset diabetes in heart failure: a prespecified analysis of the FINEARTS-HF trial. Lancet Diabetes Endocrinol 2025 Feb;13(2):107-118. doi:10.1016/S2213-8587(24)00309-7
- Bannon J, Smith JD, Van Ryzin MJ, McHugh M, Heinrich J, Walunas TL, Kho AN Design of INSPIRE: Evaluation of the effectiveness of practice facilitation on implementation of screening, brief interventions, referral to treatment and medication for unhealthy alcohol use identification and treatment in primary care. Contemp Clin Trials Commun 2025 Feb;43:101413. pii:101413
- Cai W, Liu X, Barajas S, Xiao S, Vemula S, Chen H, Yang Y, Bochers C, Henley D, Liu S et al. Polycomb group protein Mel18 inhibits hematopoietic stem cell self-renewal through repressing the transcription of self-renewal and proliferation genes. Leukemia 2025 Feb;39(2):296-307. doi:10.1038/s41375-024-02462-w
- Peterson TE, Lima JAC, Shah SJ, Bluemke DA, Bertoni AG, Liu Y, Ngo D, Varadarajan V, Mychaleckyj JC, Johnson CW et al. Proteomics of left ventricular structure in the Multi-Ethnic Study of Atherosclerosis. ESC Heart Fail 2025 Feb;12(1):239-249. doi:10.1002/ehf2.15073
- Friedewald SM, Sieniek M, Jansen S, Mahvar F, Kohlberger T, Schacht D, Bhole S, Gupta D, Prabhakara S, McKinney SM et al. Triaging mammography with artificial intelligence: an implementation study. Breast Cancer Res Treat 2025 Jan 29;. doi:10.1007/s10549-025-07616-7
- Koh J, Caron S, Watters AN, Vaidyanathan M, Melnick D, Santi A, Hudson K, Arguelles C, Mathur P, Etemadi M Technological Adjuncts to Streamline Patient Recruitment, Informed Consent, and Data Management Processes in Clinical Research: Observational Study. JMIR Form Res 2025 Jan 29;9:e58628. doi:10.2196/58628
- Gerratana L, Davis AA, Foffano L, Reduzzi C, Rossi T, Medford A, Clifton K, Shah AN, Bucheit L, Velimirovic M et al. Integrating machine learning-predicted circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) in metastatic breast cancer: A proof of principle study on endocrine resistance profiling. Cancer Lett 2025 Jan 28;609:217325. doi:10.1016/j.canlet.2024.217325
- Li EV, Ren Y, Griffin J, Han C, Yamashita R, Mitani A, Zhou R, Huang HC, Yang X, Feng FY et al. An Artificial Intelligence-Digital Pathology Algorithm Predicts Survival After Radical Prostatectomy From the Prostate, Lung, Colorectal, and Ovarian Cancer Trial. J Urol 2025 Jan 22;:101097JU0000000000004435. doi:10.1097/JU.0000000000004435
- Butt JH, Henderson AD, Jhund PS, Claggett BL, Desai AS, Lay-Flurrie J, Viswanathan P, Lage A, Scheerer MF, Lam CSP et al. Finerenone, Obesity, and Heart Failure With Mildly Reduced/Preserved Ejection Fraction: Prespecified Analysis of FINEARTS-HF. J Am Coll Cardiol 2025 Jan 21;85(2):140-155. doi:10.1016/j.jacc.2024.10.111
- Yang M, Henderson AD, Talebi A, Atherton JJ, Chiang CE, Chopra V, Comin-Colet J, Kosiborod MN, Kerr Saraiva JF, Claggett BL et al. Effect of Finerenone on the KCCQ in Patients With HFmrEF/HFpEF: A Prespecified Analysis of FINEARTS-HF. J Am Coll Cardiol 2025 Jan 21;85(2):120-136. doi:10.1016/j.jacc.2024.09.023
- Mc Causland FR, Vaduganathan M, Claggett BL, Kulac IJ, Desai AS, Jhund PS, Henderson AD, Brinker M, Perkins R, Scheerer MF et al. Finerenone and Kidney Outcomes in Patients With Heart Failure: The FINEARTS-HF Trial. J Am Coll Cardiol 2025 Jan 21;85(2):159-168. doi:10.1016/j.jacc.2024.10.091
- Desai AS, Vaduganathan M, Claggett BL, Kulac IJ, Jhund PS, Cunningham J, Borentain M, Lay-Flurrie J, Viswanathan P, Rohwedder K et al. Finerenone in Patients With a Recent Worsening Heart Failure Event: The FINEARTS-HF Trial. J Am Coll Cardiol 2025 Jan 21;85(2):106-116. doi:10.1016/j.jacc.2024.09.004
- Vaduganathan M, Claggett BL, Desai AS, Jhund PS, Lam CSP, Senni M, Shah SJ, Voors AA, Zannad F, Pitt B et al. Time to Significant Benefit of Finerenone in Patients With Heart Failure. J Am Coll Cardiol 2025 Jan 21;85(2):199-202. doi:10.1016/j.jacc.2024.09.018
- Davies MJ, van der Meer P, Verma S, Patel S, Chinnakondepalli KM, Borlaug BA, Butler J, Kitzman DW, Shah SJ, Harring S et al. Semaglutide in obesity-related heart failure with preserved ejection fraction and type 2 diabetes across baseline HbA1c levels (STEP-HFpEF DM): a prespecified analysis of heart failure and metabolic outcomes from a randomised, placebo-controlled trial. Lancet Diabetes Endocrinol 2025 Jan 20;. pii:S2213-8587(24)00304-8
- Giuffrida AS, Sheriff S, Huang V, Weinberg BD, Cooper LAD, Liu Y, Soher BJ, Treadway M, Maudsley AA, Shim H NNFit: A Self-Supervised Deep Learning Method for Accelerated Quantification of High- Resolution Short Echo Time MR Spectroscopy Datasets. Radiol Artif Intell 2025 Jan 15;:e230579. doi:10.1148/ryai.230579
- Vaduganathan M, Claggett BL, Kulac IJ, Miao ZM, Desai AS, Jhund PS, Henderson AD, Brinker M, Lay-Flurrie J, Viswanathan P et al. Effects of the Nonsteroidal MRA Finerenone With and Without Concomitant SGLT2 Inhibitor Use in Heart Failure. Circulation 2025 Jan 14;151(2):149-158. doi:10.1161/CIRCULATIONAHA.124.072055
- Lei Y, Li Z, Bui Q, DePaul O, Nicol GE, Mohr DC, Fong MWM, Metts CL, Lee SI, Tomazin SE et al. Satisfaction, user experiences, and initial efficacy of a technology-supported self-management intervention (iSMART) to improve post-stroke functioning: a remoted randomized controlled trial. Top Stroke Rehabil 2025 Jan 10;:1-15. doi:10.1080/10749357.2025.2450950
- Wang X, Li Y, Lin Z, Pla I, Gajjela R, Mattamana BB, Joshi M, Liu Y, Wang H, Zun AB et al. Micropillar-induced changes in cell nucleus morphology enhance bone regeneration by modulating the secretome. Res Sq 2025 Jan 07;. pii:rs.3.rs-5530535
- Naved BA, Han S, Koss KM, Kando MJ, Wang JJ, Weiss C, Passman MG, Wertheim JA, Luo Y, Zhang ZJ Multivariate description of gait changes in a mouse model of peripheral nerve injury and trauma. PLoS One 2025;20(1):e0312415. pii:e0312415
- Docherty KF, Henderson AD, Jhund PS, Claggett BL, Desai AS, Mueller K, Viswanathan P, Scalise A, Lam CSP, Senni M et al. Efficacy and Safety of Finerenone Across the Ejection Fraction Spectrum in Heart Failure With Mildly Reduced or Preserved Ejection Fraction: A Prespecified Analysis of the FINEARTS-HF Trial. Circulation 2025 Jan 07;151(1):45-58. doi:10.1161/CIRCULATIONAHA.124.072011
- Liebovitz DM Navigating Uncertainty in Digital Health Education. JAMA Netw Open 2025 Jan 02;8(1):e2453095. doi:10.1001/jamanetworkopen.2024.53095
- Swaroop A, Yue F Chromatin hubs drive key regulatory networks in leukemia. Mol Cell 2025 Jan 02;85(1):1-2. doi:10.1016/j.molcel.2024.12.011
- Stiles-Shields C, Reyes KM, Lakhtakia T, Smith SR, Barnas OE, Gray EL, Krause CJ, Kruzan KP, Kwasny MJ, Mir Z et al. Correction: A personal sensing technology enabled service versus a digital psychoeducation control for primary care patients with depression and anxiety: a pilot randomized controlled trial. BMC Psychiatry 2025 Jan 02;25(1):4. pii:4
- Idnay B, Xu Z, Adams WG, Adibuzzaman M, Anderson NR, Bahroos N, Bell DS, Bumgardner C, Campion T, Castro M et al. Environment scan of generative AI infrastructure for clinical and translational science. Npj Health Syst 2025;2(1):4. pii:4
- Ragon B, Seymour A, Whipple EC, Surkis A, Haberstroh A, Muilenburg J, Rethlefsen ML, Aspinall EE, Deaver J, Dexter N et al. The role of information science within the clinical translational science ecosystem. J Clin Transl Sci 2025;8(1):e224. pii:e224
- Vardeny O, Vaduganathan M, Claggett BL, Desai AS, Jhund PS, Lam CSP, Senni M, Shah SJ, Voors AA, Zannad F et al. Finerenone, Serum Potassium, and Clinical Outcomes in Heart Failure With Mildly Reduced or Preserved Ejection Fraction. JAMA Cardiol 2025 Jan 01;10(1):42-48. pii:e244539
- Nargesi AA, Adejumo P, Dhingra LS, Rosand B, Hengartner A, Coppi A, Benigeri S, Sen S, Ahmad T, Nadkarni GN et al. Automated Identification of Heart Failure With Reduced Ejection Fraction Using Deep Learning-Based Natural Language Processing. JACC Heart Fail 2025 Jan;13(1):75-87. doi:10.1016/j.jchf.2024.08.012
- Sadeghpour A, Jiang Z, Hummel YM, Frost M, Lam CSP, Shah SJ, Lund LH, Stone GW, Swaminathan M, Weissman NJ et al. An Automated Machine Learning-Based Quantitative Multiparametric Approach for Mitral Regurgitation Severity Grading. JACC Cardiovasc Imaging 2025 Jan;18(1):1-12. doi:10.1016/j.jcmg.2024.06.011
- Shimbo D, Shah RU, Abdalla M, Agarwal R, Ahmad FS, Anaya G, Attia ZI, Bull S, Chang AR, Commodore-Mensah Y et al. Transforming Hypertension Diagnosis and Management in The Era of Artificial Intelligence: A 2023 National Heart, Lung, and Blood Institute (NHLBI) Workshop Report. Hypertension 2025 Jan;82(1):36-45. doi:10.1161/HYPERTENSIONAHA.124.22095
- Naved BA, Luo Y Contrasting rule and machine learning based digital self triage systems in the USA. NPJ Digit Med 2024 Dec 27;7(1):381. pii:381
- Gould A, Luan Y, Hou Y, Korobova FV, Chen L, Arrieta VA, Amidei C, Ward R, Gomez C, Castro B et al. Endothelial Response to Blood-Brain Barrier Disruption in the Human Brain. JCI Insight 2024 Dec 26;. pii:e187328
- Ambrosy AP, Sauer AJ, Patel S, Windsor SL, Borlaug BA, Husain M, Inzucchi SE, Kitzman DW, McGuire DK, Shah SJ et al. Baseline kidney function and the effects of dapagliflozin on health status in heart failure in DEFINE-HF and PRESERVED-HF. ESC Heart Fail 2024 Dec 24;. doi:10.1002/ehf2.15184
- Seyithanoglu D, Durak G, Keles E, Medetalibeyoglu A, Hong Z, Zhang Z, Taktak YB, Cebeci T, Tiwari P, Velichko YS et al. Advances for Managing Pancreatic Cystic Lesions: Integrating Imaging and AI Innovations. Cancers (Basel) 2024 Dec 22;16(24). pii:4268
- Luo Y, Fraser L, Jezykowski J, Gupta NA, Miethke AG, Taylor SA, Alonso EM, Horslen S, Kohli R, Molleston JP et al. Interleukin 8-CXCR2-mediated neutrophil extracellular trap formation in biliary atresia associated with neutrophil extracellular trap-induced stellate cell activation. Hepatology 2024 Dec 18;. doi:10.1097/HEP.0000000000001195
- Zamani P, Shah SJ, Cohen JB, Zhao M, Yang W, Afable JL, Caturla M, Maynard H, Pourmussa B, Demastus C et al. Potassium Nitrate in Heart Failure With Preserved Ejection Fraction: A Randomized Clinical Trial. JAMA Cardiol 2024 Dec 18;. doi:10.1001/jamacardio.2024.4417
- Fejzo M, Wang X, Zöllner J, Pujol-Gualdo N, Laisk T, , Finer S, van Heel DA, , Brumpton B et al. Multi-ancestry GWAS of severe pregnancy nausea and vomiting identifies risk loci associated with appetite, insulin signaling, and brain plasticity. Res Sq 2024 Dec 16;. pii:rs.3.rs-5487737
- Shin J, Luo Y Relationship between exposure to multiple heavy metals and depressive symptoms in the US: The impact of alcohol consumption. Heliyon 2024 Dec 15;10(23):e40221. pii:e40221
- Michelson KN, Fishman AC, Feinberg EC, Ross S, Wald HS, Auerbach C, Roth S Antisemitism in American Healthcare: A Survey Study of Reported Experiences. J Gen Intern Med 2024 Dec 11;. doi:10.1007/s11606-024-09159-x
- Stefanopoulos L, Kim BW, Sheppard J, Azcona EA, Vike NL, Bari S, Lalvani S, Woodward S, Maglaveras N, Block M et al. Discrete, recurrent, and scalable patterns in non-operant judgement underlie affective picture ratings. Cogn Process 2024 Dec 07;. doi:10.1007/s10339-024-01250-9
- Quiriarte H, Noland RC, Stampley JE, Davis G, Li Z, Cho E, Kim Y, Doiron J, Spielmann G, Ghosh S et al. Exercise Therapy Rescues Skeletal Muscle Dysfunction and Exercise Intolerance in Cardiometabolic HFpEF. JACC Basic Transl Sci 2024 Dec;9(12):1409-1425. doi:10.1016/j.jacbts.2024.07.009
- Wang MC, Awoyemi T, Allen NB, Shah R, Nayor M, Luo Y, Lima JAC, Lloyd-Jones DM, Khan SS Latent class analysis of cardiac structure and function and association with premature cardiovascular disease: The Coronary Artery Risk Development in Young Adults (CARDIA) study. Am J Prev Cardiol 2024 Dec;20:100889. pii:100889
- Vaduganathan M, Filippatos G, Claggett BL, Desai AS, Jhund PS, Henderson A, Brinker M, Kolkhof P, Schloemer P, Lay-Flurrie J et al. Author Correction: Finerenone in heart failure and chronic kidney disease with type 2 diabetes: FINE-HEART pooled analysis of cardiovascular, kidney and mortality outcomes. Nat Med 2024 Dec;30(12):3778. doi:10.1038/s41591-024-03372-1
- Fudim M, Borlaug BA, Mohan RC, Price MJ, Fail P, Goyal P, Hummel SL, Zirakashvili T, Shaburishvili T, Patel RB et al. Endovascular Ablation of the Greater Splanchnic Nerve in Heart Failure With Preserved Ejection Fraction: The REBALANCE-HF Randomized Clinical Trial. JAMA Cardiol 2024 Dec 01;9(12):1143-1153. doi:10.1001/jamacardio.2024.2612
- Haynes G, Muhammad F, Weber KA, Khan AF, Hameed S, Shakir H, Van Hal M, Dickson D, Rohan M, Dhaher Y et al. Tract-specific magnetization transfer ratio provides insights into the severity of degenerative cervical myelopathy. Spinal Cord 2024 Dec;62(12):700-707. doi:10.1038/s41393-024-01036-y