Publications
Browse the list below to see the latest scientific publications stemming from our center faculty’s work. To view publications of specific CHIP faculty, please visit About Us and select a profile link.
- Gupta Y, Friedman DJ, McNulty MT, Khan A, Lane B, Wang C, Ke J, Jin G, Wooden B, Knob AL et al. Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease. Nat Commun 2023 Nov 30;14(1):7836. pii:7836
- Ferar K, Hall TO, Crawford DC, Rowley R, Satterfield BA, Li R, Gragert L, Karlson EW, de Andrade M, Kullo IJ et al. Author Correction: Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection. Sci Rep 2023 Nov 15;13(1):19972. pii:19972
- Wösten-van Asperen RM, la Roi-Teeuw HM, van Amstel RB, Bos LD, Tissing WJ, Jordan I, Dohna-Schwake C, Bottari G, Pappachan J, Crazzolara R et al. Distinct clinical phenotypes in paediatric cancer patients with sepsis are associated with different outcomes-an international multicentre retrospective study. EClinicalMedicine 2023 Nov;65:102252. pii:102252
- Ross SM, Wang A, Anthony L, Persell SD, Yu J, Kho AN Is more better? The impact of implementing more interventions for hypertension control in a practice facilitation study for small- and medium-sized practices. J Hum Hypertens 2023 Nov;37(11):1007-1014. doi:10.1038/s41371-023-00813-1
- Shah KP, Khan SS, Baldridge AS, Grady KL, Cella D, Goyal P, Allen LA, Smith JD, Lagu TC, Ahmad FS Health Status in Heart Failure and Cancer: Analysis of the Medicare Health Outcomes Survey 2016-2020. JACC Heart Fail 2023 Oct 30;. pii:S2213-1779(23)00678-9
- Ferar K, Hall TO, Crawford DC, Rowley R, Satterfield BA, Li R, Gragert L, Karlson EW, de Andrade M, Kullo IJ et al. Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection. Sci Rep 2023 Oct 28;13(1):18532. pii:18532
- Hosseini M, Gao CA, Liebovitz DM, Carvalho AM, Ahmad FS, Luo Y, MacDonald N, Holmes KL, Kho A An exploratory survey about using ChatGPT in education, healthcare, and research. PLoS One 2023;18(10):e0292216. pii:e0292216
- Forrest N, Jackson KL, Tran S, Pacheco JA, Mitrovic V, Furmanchuk A, Kho AN, Ramsey-Goldman R, Walunas TL Identification and assessment of classification criteria attributes for systemic lupus erythematosus in a regional medical record data network. Lupus Sci Med 2023 Oct;10(2). pii:e000963
- Krefman AE, Ciolino JD, Kan AK, Maki B, McHugh M, Smith JD, Bannon J, Carroll AJ, Bustamante P, Frye C et al. Rationale and design for Healthy Hearts for Michigan (HH4M): A pragmatic single-arm hybrid effectiveness-implementation study. Contemp Clin Trials Commun 2023 Oct;35:101199. pii:101199
- McHugh M, Heinrich J, Philbin S, Bishop D, Smith JD, Knapke JM, Day A, Walunas TL Declining Participation in Primary Care Quality Improvement Research: A Qualitative Study. Ann Fam Med 2023;21(5):388-394. doi:10.1370/afm.3007
- Eickelberg G, Sanchez-Pinto LN, Kline AS, Luo Y Transportability of bacterial infection prediction models for critically ill patients. J Am Med Inform Assoc 2023 Aug 30;. pii:ocad174
- Atreya MR, Bennett TD, Geva A, Faustino EVS, Rogerson CM, Lutfi R, Cvijanovich NZ, Bigham MT, Nowak J, Schwarz AJ et al. External validation and biomarker assessment of a high-risk, data-driven pediatric sepsis phenotype characterized by persistent hypoxemia, encephalopathy, and shock. Res Sq 2023 Aug 02;. pii:rs.3.rs-3216613
- Mao C, Xu J, Rasmussen L, Li Y, Adekkanattu P, Pacheco J, Bonakdarpour B, Vassar R, Shen L, Jiang G et al. AD-BERT: Using pre-trained language model to predict the progression from mild cognitive impairment to Alzheimer's disease. J Biomed Inform 2023 Aug;144:104442. doi:10.1016/j.jbi.2023.104442
- Wang H, Ding YJ, Luo Y Future of ChatGPT in Pharmacovigilance. Drug Saf 2023 Aug;46(8):711-713. doi:10.1007/s40264-023-01315-2
- Naidech AM, Wang H, Hutch M, Murphy J, Paparello J, Bath P, Srivastava A, Luo Y Blood pressure medication and acute kidney injury after intracerebral haemorrhage: an analysis of the ATACH-II trial. BMJ Neurol Open 2023;5(2):e000458. pii:e000458
- Cousins HC, Kline AS, Wang C, Qu Y, Zengel J, Carette J, Wang M, Altman RB, Luo Y, Cong L Integrative analysis of functional genomic screening and clinical data identifies a protective role for spironolactone in severe COVID-19. Cell Rep Methods 2023 Jul 24;3(7):100503. pii:100503
- Canning C, Guo J, Narang A, Thomas JD, Ahmad FS The Emerging Role of Artificial Intelligence in Valvular Heart Disease. Heart Fail Clin 2023 Jul;19(3):391-405. doi:10.1016/j.hfc.2023.03.001
- Hoffmann AD, Weinberg SE, Swaminathan S, Chaudhuri S, Almubarak HF, Schipma MJ, Mao C, Wang X, El-Shennawy L, Dashzeveg NK et al. Unique molecular signatures sustained in circulating monocytes and regulatory T cells in convalescent COVID-19 patients. Clin Immunol 2023 Jul;252:109634. doi:10.1016/j.clim.2023.109634
- Bilaver LA, Wang H, Naidech AM, Luo Y, Das R, Sehgal S, Gupta R Natural language processing of pediatric progress notes for the identification of food allergy. J Allergy Clin Immunol Pract 2023 Jul;11(7):2242-2244.e2. doi:10.1016/j.jaip.2023.04.014
- Lutgendorf SK, Zia S, Luo Y, O'Donnell M, van Bokhoven A, Bradley CS, Gallup R, Pierce J, Taple BJ, Naliboff BD et al. Early and recent exposure to adversity, TLR-4 stimulated inflammation, and diurnal cortisol in women with interstitial cystitis/bladder pain syndrome: A MAPP research network study. Brain Behav Immun 2023 Jul;111:116-123. doi:10.1016/j.bbi.2023.03.024
- Gao CA, Markov NS, Stoeger T, Pawlowski A, Kang M, Nannapaneni P, Grant RA, Pickens C, Walter JM, Kruser JM et al. Machine learning links unresolving secondary pneumonia to mortality in patients with severe pneumonia, including COVID-19. J Clin Invest 2023 Jun 15;133(12). pii:e170682
- Li Y, Luo Y Spatial Transcriptomic Cell-type Deconvolution Using Graph Neural Networks. bioRxiv 2023 Jun 09;. pii:2023.03.10.532112
- Sanchez-Pinto LN, Bennet TD, Stroup EK, Luo Y, Atreya M, Bubeck Wardenburg J, Chong G, Geva A, Faustino EVS, Farris RW et al. Derivation, Validation, and Clinical Relevance of a Pediatric Sepsis Phenotype With Persistent Hypoxemia, Encephalopathy, and Shock. Pediatr Crit Care Med 2023 Jun 02;24(10):795-806. doi:10.1097/PCC.0000000000003292
- Schepart A, Burton A, Durkin L, Fuller A, Charap E, Bhambri R, Ahmad FS Artificial intelligence-enabled tools in cardiovascular medicine: A survey of current use, perceptions, and challenges. Cardiovasc Digit Health J 2023 Jun;4(3):101-110. doi:10.1016/j.cvdhj.2023.04.003
- Joo YY, Pacheco JA, Thompson WK, Rasmussen-Torvik LJ, Rasmussen LV, Lin FTJ, Andrade M, Borthwick KM, Bottinger E, Cagan A et al. Multi-ancestry genome- and phenome-wide association studies of diverticular disease in electronic health records with natural language processing enriched phenotyping algorithm. PLoS One 2023;18(5):e0283553. pii:e0283553
- Patterson V, Ullah F, Bryant L, Griffin JN, Sidhu A, Saliganan S, Blaile M, Saenz MS, Smith R, Ellingwood S et al. Abrogation of MAP4K4 protein function causes congenital anomalies in humans and zebrafish. Sci Adv 2023 Apr 28;9(17):eade0631. pii:eade0631
- Gao CA, Howard FM, Markov NS, Dyer EC, Ramesh S, Luo Y, Pearson AT Comparing scientific abstracts generated by ChatGPT to real abstracts with detectors and blinded human reviewers. NPJ Digit Med 2023 Apr 26;6(1):75. pii:75
- Wang H, Li Y, Hutch MR, Kline AS, Otero S, Mithal LB, Miller ES, Naidech A, Luo Y Patterns of diverse and changing sentiments towards COVID-19 vaccines: a sentiment analysis study integrating 11 million tweets and surveillance data across over 180 countries. J Am Med Inform Assoc 2023 Apr 19;30(5):923-931. doi:10.1093/jamia/ocad029
- Hosseini M, Gao CA, Liebovitz D, Carvalho A, Ahmad FS, Luo Y, MacDonald N, Holmes K, Kho A An exploratory survey about using ChatGPT in education, healthcare, and research. medRxiv 2023 Apr 03;. pii:2023.03.31.23287979
- Liu Y, Luo Y, Naidech AM Big Data in Stroke: How to Use Big Data to Make the Next Management Decision. Neurotherapeutics 2023 Apr;20(3):744-757. doi:10.1007/s13311-023-01358-4
- Xiao B, Velez Edwards DR, Lucas A, Drivas T, Gray K, Keating B, Weng C, Jarvik GP, Hakonarson H, Kottyan L et al. Inference of Causal Relationships Between Genetic Risk Factors for Cardiometabolic Phenotypes and Female-Specific Health Conditions. J Am Heart Assoc 2023 Mar 07;12(5):e026561. pii:e026561
- Furmanchuk A, Rydland KJ, Hsia RY, Mackersie R, Shi M, Hauser MW, Kho A, Bilimoria KY, Stey AM Geographic Disparities in Re-triage Destinations Among Seriously Injured Californians. Ann Surg Open 2023 Mar;4(1). pii:e270
- Bunney G, Tran S, Han S, Gu C, Wang H, Luo Y, Dresden S Using Machine Learning to Predict Hospital Disposition With Geriatric Emergency Department Innovation Intervention. Ann Emerg Med 2023 Mar;81(3):353-363. doi:10.1016/j.annemergmed.2022.07.026
- Kim M, Kwasny MJ, Bailey SC, Benavente JY, Zheng P, Bonham M, Luu HQ, Cecil P, Agyare P, O'Conor R et al. MidCog study: a prospective, observational cohort study investigating health literacy, self-management skills and cognitive function in middle-aged adults. BMJ Open 2023 Feb 23;13(2):e071899. pii:e071899
- Brandt PS, Kho A, Luo Y, Pacheco JA, Walunas TL, Hakonarson H, Hripcsak G, Liu C, Shang N, Weng C et al. Characterizing variability of electronic health record-driven phenotype definitions. J Am Med Inform Assoc 2023 Feb 16;30(3):427-437. doi:10.1093/jamia/ocac235
- Gay HC, Yu J, Persell SD, Linder JA, Srivastava A, Isakova T, Huffman MD, Khan SS, Mutharasan RK, Petito LC et al. Comparison of Sodium-Glucose Cotransporter-2 Inhibitor and Glucagon-Like Peptide-1 Receptor Agonist Prescribing in Patients With Diabetes Mellitus With and Without Cardiovascular Disease. Am J Cardiol 2023 Feb 15;189:121-130. doi:10.1016/j.amjcard.2022.10.041
- Ahmad FS, Ahmad T, Allen LA When the Whole Is the Sum of Its Parts: Validation of the Heart Failure Collaboratory Medication Composite Score in Denmark. Circ Heart Fail 2023 Feb;16(2):e010309. doi:10.1161/CIRCHEARTFAILURE.122.010309
- Li Y, Wehbe RM, Ahmad FS, Wang H, Luo Y A comparative study of pretrained language models for long clinical text. J Am Med Inform Assoc 2023 Jan 18;30(2):340-347. doi:10.1093/jamia/ocac225
- Ahmad FS, Persell SD Nudging to Improve Cardiovascular Care-Clinicians, Patients, or Both. JAMA Cardiol 2023 Jan 01;8(1):31-32. doi:10.1001/jamacardio.2022.4382
- Ramgopal S, Sanchez-Pinto LN, Horvat CM, Carroll MS, Luo Y, Florin TA Artificial intelligence-based clinical decision support in pediatrics. Pediatr Res 2023 Jan;93(2):334-341. doi:10.1038/s41390-022-02226-1
- Zeng X, Wang F, Luo Y, Kang SG, Tang J, Lightstone FC, Fang EF, Cornell W, Nussinov R, Cheng F Deep generative molecular design reshapes drug discovery. Cell Rep Med 2022 Dec 20;3(12):100794. pii:100794
- Deng Y, Ghamsari F, Lu A, Yu J, Zhao L, Kho AN Use of real-world evidence data to evaluate the comparative effectiveness of second-line type 2 diabetes medications on chronic kidney disease. J Clin Transl Endocrinol 2022 Dec;30:100309. pii:100309
- Gutiérrez-Sacristán A, Serret-Larmande A, Hutch MR, Sáez C, Aronow BJ, Bhatnagar S, Bonzel CL, Cai T, Devkota B, Hanauer DA et al. Hospitalizations Associated With Mental Health Conditions Among Adolescents in the US and France During the COVID-19 Pandemic. JAMA Netw Open 2022 Dec 01;5(12):e2246548. pii:e2246548
- Xu J, Mao C, Hou Y, Luo Y, Binder JL, Zhou Y, Bekris LM, Shin J, Hu M, Wang F et al. Interpretable deep learning translation of GWAS and multi-omics findings to identify pathobiology and drug repurposing in Alzheimer's disease. Cell Rep 2022 Nov 29;41(9):111717. doi:10.1016/j.celrep.2022.111717
- Levin MG, Tsao NL, Singhal P, Liu C, Vy HMT, Paranjpe I, Backman JD, Bellomo TR, Bone WP, Biddinger KJ et al. Genome-wide association and multi-trait analyses characterize the common genetic architecture of heart failure. Nat Commun 2022 Nov 14;13(1):6914. pii:6914
- Li Y, Wang H, Luo Y Improving Fairness in the Prediction of Heart Failure Length of Stay and Mortality by Integrating Social Determinants of Health. Circ Heart Fail 2022 Nov;15(11):e009473. doi:10.1161/CIRCHEARTFAILURE.122.009473
- Namjou B, Lape M, Malolepsza E, DeVore SB, Weirauch MT, Dikilitas O, Jarvik GP, Kiryluk K, Kullo IJ, Liu C et al. Multiancestral polygenic risk score for pediatric asthma. J Allergy Clin Immunol 2022 Nov;150(5):1086-1096. doi:10.1016/j.jaci.2022.03.035
- Piunti A, Meghani K, Yu Y, Robertson AG, Podojil JR, McLaughlin KA, You Z, Fantini D, Chiang M, Luo Y et al. Immune activation is essential for the antitumor activity of EZH2 inhibition in urothelial carcinoma. Sci Adv 2022 Oct 07;8(40):eabo8043. pii:eabo8043
- Cheema B, Mutharasan RK, Sharma A, Jacobs M, Powers K, Lehrer S, Wehbe FH, Ronald J, Pifer L, Rich JD et al. Augmented Intelligence to Identify Patients With Advanced Heart Failure in an Integrated Health System. JACC Adv 2022 Oct;1(4). pii:100123
- Li Y, Wu X, Yang P, Jiang G, Luo Y Machine Learning for Lung Cancer Diagnosis, Treatment, and Prognosis. Genomics Proteomics Bioinformatics 2022 Oct;20(5):850-866. doi:10.1016/j.gpb.2022.11.003