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Using Large Language Models (LLMs) Responsibly

🔐 Understanding Data Security Levels at Northwestern

Northwestern University classifies data into four levels based on sensitivity:

  • Level 1: Public data (e.g., published works already available online)
  • Level 2: Internal data (e.g., unpublished research, draft manuscripts)
  • Level 3: Confidential data (e.g., Protected Health Information [PHI])
  • Level 4: Highly restricted data (e.g., government-classified information)

Northwestern definitions:

📦 Reminder of where you can store PHI here

 


⚠️ What Can Be Used with Public LLMs?

Only Level 1 (public) data should be entered into publicly available LLMs such as:

  • ChatGPT
  • Claude
  • Gemini

These tools may retain input data, share it with third-party providers, or use it for model training—posing risks even if the data doesn’t appear sensitive.


🏥 Feinberg School of Medicine Policy

Feinberg medical students must follow specific guidelines for using generative AI tools:


 Approved Tools for Higher-Sensitivity Data

Microsoft Copilot

copilotscreenshot

NM Chat

🧪 Research Use and IRB-Approved Projects

For IRB-approved research involving sensitive data:


LLM Tool Comparison for Sensitive Data Use

the table shows LLM Tool Comparison for Sensitive Data Use

Tool

Access Requirements

Can Input Minimal Necessary PHI/PII?

Data Level Allowed

Public LLMs (ChatGPT, Gemini, Claude, etc.)

Publicly accessible

❌ No

Level 1 only (Public data)

Microsoft Copilot (NU)
copilot.cloud.microsoft

Sign in with @northwestern.edu

❌ No

Level 2 (Internal data)

Microsoft Copilot (NM)
copilot.cloud.microsoft

Sign in with @nm.org

❌ No

Level 2 (Internal data)

NM Chat
chat.nm.org

Sign in via Citrix/VPN

✅ Yes

Level 3 (PHI/PII)

Fully Local Models

Depends on configuration and approval

⚠️ It depends

Case-by-case (requires review)

Microsoft Azure OpenAI APIs

Special research account + IRB + Limited Access Review

⚠️ It depends

Case-by-case (requires review)

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