Northwestern University Feinberg School of Medicine
Faculty Profiles
Isabelle G De Plaen, MD

Isabelle G De Plaen, MD

Associate Professor of Pediatrics (Neonatology)

Focus of Work


Isabelle De Plaen, MD, is an attending physician in the Division of Neonatology (Neonatal Intensive Care Unit) at Lurie Children’s, Associate Professor of Pediatrics at Northwestern University Feinberg School of Medicine, and a member of the Center for Intestinal and Liver Inflammation Research at Stanley Manne Children’s Research Institute.

Academic Focus

Dr. De Plaen’s research focuses on understanding mucosal microcirculatory and inflammatory mechanisms contributing to necrotizing enterocolitis (NEC), a devastating disease of the premature infant, causing sudden bowel inflammation and necrosis.


Education and Certification

  • MD: Universite Catholique de Louvain (1989)
  • Residency: California Pacific Medical Center, Pediatrics (1994)
  • Fellowship: Northwestern University, McGaw Medical Center (Children’s Memorial Hospital), Neonatal/Perinatal Medicine (1998)
  • Board Certification: Neonatal-Perinatal Medicine, Pediatrics