Northwestern’s interdisciplinary biomedical PhD training program.

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Who We Are

The Walter S. and Lucienne Driskill Graduate Program in Life Sciences is a comprehensive, interdisciplinary PhD program that trains students in biomedical sciences while giving them the flexibility to pursue a variety of research interests and dual degrees.

Research and Mentors

Faculty work with students to conduct research across disciplines, including biochemistry, biology, genetics, immunology, microbiology, neurobiology, pharmacology and computational biology.

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Pre-illness data reveals differences in multiple metabolites and metabolic pathways in those who do and do not recover from infectious mononucleosis.

Jason LA, Conroy KE, Furst J, Vasan K, Katz BZ.

Mol Omics. 2022 May 31. doi: 10.1039/d2mo00124a. Online ahead of print.

Fine mapping and candidate gene analysis of a dravet syndrome modifier locus on mouse chromosome 11.

Kearney JA, Copeland-Hardin LD, Duarte S, Zachwieja NA, Eckart-Frank IK, Hawkins NA.

Mamm Genome. 2022 May 23. doi: 10.1007/s00335-022-09955-y. Online ahead of print.

Latent Membrane Proteins from EBV Differentially Target Cellular Pathways to Accelerate MYC-induced Lymphomagenesis.

Ikeda M, Hayes CK, Schaller SJ, Longnecker R.

Blood Adv. 2022 May 23:bloodadvances.2022007695. doi: 10.1182/bloodadvances.2022007695. Online ahead of print.

Author Correction: Reduced expression of mitochondrial complex I subunit Ndufs2 does not impact healthspan in mice.

McElroy GS, Chakrabarty RP, D'Alessandro KB, Hu YS, Vasan K, Tan J, Stoolman JS, Weinberg SE, Steinert EM, Reyfman PA, Singer BD, Ladiges WC, Gao L, Lopéz-Barneo J, Ridge K, Budinger GRS, Chandel NS.

Sci Rep. 2022 May 17;12(1):8191. doi: 10.1038/s41598-022-12069-9.

Ketamine activates adult-born immature granule neurons to rapidly alleviate depression-like behaviors in mice.

Rawat R, Tunc-Ozcan E, McGuire TL, Peng CY, Kessler JA.

Nat Commun. 2022 May 12;13(1):2650. doi: 10.1038/s41467-022-30386-5.

Tbx2 is a master regulator of inner versus outer hair cell differentiation.

García-Añoveros J, Clancy JC, Foo CZ, García-Gómez I, Zhou Y, Homma K, Cheatham MA, Duggan A.

Nature. 2022 May;605(7909):298-303. doi: 10.1038/s41586-022-04668-3. Epub 2022 May 4.

Mitochondrial electron transport chain is necessary for NLRP3 inflammasome activation.

Billingham LK, Stoolman JS, Vasan K, Rodriguez AE, Poor TA, Szibor M, Jacobs HT, Reczek CR, Rashidi A, Zhang P, Miska J, Chandel NS.

Nat Immunol. 2022 May;23(5):692-704. doi: 10.1038/s41590-022-01185-3. Epub 2022 Apr 28.

A MYC inhibitor selectively alters the MYC and MAX cistromes and modulates the epigenomic landscape to regulate target gene expression.

Holmes AG, Parker JB, Sagar V, Truica MI, Soni PN, Han H, Schiltz GE, Abdulkadir SA, Chakravarti D.

Sci Adv. 2022 Apr 29;8(17):eabh3635. doi: 10.1126/sciadv.abh3635. Epub 2022 Apr 27.

HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming in prostate cancer.

Lu X, Fong KW, Gritsina G, Wang F, Baca SC, Brea LT, Berchuck JE, Spisak S, Ross J, Morrissey C, Corey E, Chandel NS, Catalona WJ, Yang X, Freedman ML, Zhao JC, Yu J.

Nat Genet. 2022 May;54(5):670-683. doi: 10.1038/s41588-022-01045-8. Epub 2022 Apr 25.

Herpes Simplex Virus (HSV)-2 Variation Contributes to Neurovirulence During Neonatal Infection.

Hayes CK, Villota CK, McEnany FB, Cerón S, Awasthi S, Szpara ML, Friedman HM, Leib DA, Longnecker R, Weitzman MD, Akhtar LN.

J Infect Dis. 2022 Apr 22:jiac151. doi: 10.1093/infdis/jiac151. Online ahead of print.

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