Northwestern University Feinberg School of Medicine
Driskill Graduate Program in Life Sciences

Comprehensive, interdisciplinary training in modern biomedical sciences.

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Who We Are

The Walter S. and Lucienne Driskill Graduate Program in Life Sciences is a comprehensive, interdisciplinary PhD program that trains students in biomedical sciences while giving them the flexibility to pursue a variety of research interests, dual degrees and specialized tracks.

Research and Mentors

Faculty work with students to conduct research across disciplines, including biochemistry, biology, genetics, immunology, microbiology, neurobiology, pharmacology and biomedical informatics.

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Student Publications

RRSP and RID Effector Domains Dominate Virulence Impact of Vibrio vulnificus MARTX Toxin.

Gavin HE, Satchell KJF.

J Infect Dis. 2018 Oct 5. doi: 10.1093/infdis/jiy590. [Epub ahead of print]

The bacterial Ras/Rap1 site-specific endopeptidase RRSP cleaves Ras through an atypical mechanism to disrupt Ras-ERK signaling.

Biancucci M, Minasov G, Banerjee A, Herrera A, Woida PJ, Kieffer MB, Bindu L, Abreu-Blanco M, Anderson WF, Gaponenko V, …

Sci Signal. 2018 Oct 2;11(550). pii: eaat8335. doi: 10.1126/scisignal.aat8335.

Methylation-dependent Tissue Factor suppression contributes to the reduced malignancy of IDH1 mutant gliomas.

Unruh D, Mirkov S, Wray B, Drumm M, Lamano J, Li YD, Haider QF, Javier R, McCortney K, Saratsis AM, Scholtens DM, …

Clin Cancer Res. 2018 Sep 28. pii: clincanres.1222.2018. doi: 10.1158/1078-0432.CCR-18-1222. [Epub ahead of print]

Role of gram-positive bacteria in chronic pelvic pain syndrome (CPPS).

Murphy SF, Anker JF, Mazur DJ, Hall C, Schaeffer AJ, Thumbikat P.

Prostate. 2018 Sep 21. doi: 10.1002/pros.23721. [Epub ahead of print]

The exquisitely cooperative nature of Orai1 channel activation.

Yeung PS, Prakriya M.

J Gen Physiol. 2018 Oct 1;150(10):1352-1355. doi: 10.1085/jgp.201812172. Epub 2018 Sep 14. No abstract available.

ER-associated ubiquitin ligase HRD1 programs liver metabolism by targeting multiple metabolic enzymes.

Wei J, Yuan Y, Chen L, Xu Y, Zhang Y, Wang Y, Yang Y, Peek CB, Diebold L, Yang Y, Gao B, Jin C, Melo-Cardenas J, …

Nat Commun. 2018 Sep 10;9(1):3659. doi: 10.1038/s41467-018-06091-7.

Cdt1 stabilizes kinetochore-microtubule attachments via an Aurora B kinase-dependent mechanism.

Agarwal S, Smith KP, Zhou Y, Suzuki A, McKenney RJ, Varma D.

J Cell Biol. 2018 Oct 1;217(10):3446-3463. doi: 10.1083/jcb.201705127. Epub 2018 Aug 28.

Human iPSC-derived trigeminal neurons lack constitutive TLR3-dependent immunity that protects cortical neurons from HSV-1 infection.

Zimmer B, Ewaleifoh O, Harschnitz O, Lee YS, Peneau C, McAlpine JL, Liu B, Tchieu J, Steinbeck JA, Lafaille F, Volpi S, …

Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8775-E8782. doi: 10.1073/pnas.1809853115. Epub 2018 Aug 28.

Hexokinase 2 is dispensable for T cell-dependent immunity.

Mehta MM, Weinberg SE, Steinert EM, Chhiba K, Martinez CA, Gao P, Perlman HR, Bryce P, Hay N, Chandel NS.

Cancer Metab. 2018 Aug 17;6:10. doi: 10.1186/s40170-018-0184-5. eCollection 2018.

Apigenin Inhibits UVB-Induced Skin Carcinogenesis: The Role of Thrombospondin-1 as an Anti-Inflammatory Factor.

Mirzoeva S, Tong X, Bridgeman BB, Plebanek MP, Volpert OV.

Neoplasia. 2018 Sep;20(9):930-942. doi: 10.1016/j.neo.2018.07.005. Epub 2018 Aug 15.

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