Northwestern’s interdisciplinary biomedical PhD training program.

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Who We Are

The Walter S. and Lucienne Driskill Graduate Program in Life Sciences is a comprehensive, interdisciplinary PhD program that trains students in biomedical sciences while giving them the flexibility to pursue a variety of research interests and dual degrees.

Research and Mentors

Faculty work with students to conduct research across disciplines, including biochemistry, biology, genetics, immunology, microbiology, neurobiology, pharmacology and computational biology.

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VEGFR2 signals with VE-cadherin and PECAM to facilitate leukocyte transendothelial migration.

Sullivan DP, Fu TA, Weber EW, Gonzalez AP, Dalal PJ, Rutledge NS, Muller WA.

FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.R5498.

Ketamine activates adult-born immature granule neurons to rapidly alleviate depression-like behaviors in mice.

Rawat R, Tunc-Ozcan E, McGuire TL, Peng CY, Kessler JA.

Nat Commun. 2022 May 12;13(1):2650. doi: 10.1038/s41467-022-30386-5.

Tbx2 is a master regulator of inner versus outer hair cell differentiation.

García-Añoveros J, Clancy JC, Foo CZ, García-Gómez I, Zhou Y, Homma K, Cheatham MA, Duggan A.

Nature. 2022 May;605(7909):298-303. doi: 10.1038/s41586-022-04668-3. Epub 2022 May 4.

Mitochondrial electron transport chain is necessary for NLRP3 inflammasome activation.

Billingham LK, Stoolman JS, Vasan K, Rodriguez AE, Poor TA, Szibor M, Jacobs HT, Reczek CR, Rashidi A, Zhang P, Miska J, Chandel NS.

Nat Immunol. 2022 May;23(5):692-704. doi: 10.1038/s41590-022-01185-3. Epub 2022 Apr 28.

A MYC inhibitor selectively alters the MYC and MAX cistromes and modulates the epigenomic landscape to regulate target gene expression.

Holmes AG, Parker JB, Sagar V, Truica MI, Soni PN, Han H, Schiltz GE, Abdulkadir SA, Chakravarti D.

Sci Adv. 2022 Apr 29;8(17):eabh3635. doi: 10.1126/sciadv.abh3635. Epub 2022 Apr 27.

HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming in prostate cancer.

Lu X, Fong KW, Gritsina G, Wang F, Baca SC, Brea LT, Berchuck JE, Spisak S, Ross J, Morrissey C, Corey E, Chandel NS, Catalona WJ, Yang X, Freedman ML, Zhao JC, Yu J.

Nat Genet. 2022 Apr 25. doi: 10.1038/s41588-022-01045-8. Online ahead of print.

Herpes Simplex Virus (HSV)-2 Variation Contributes to Neurovirulence During Neonatal Infection.

Hayes CK, Villota CK, McEnany FB, Cerón S, Awasthi S, Szpara ML, Friedman HM, Leib DA, Longnecker R, Weitzman MD, Akhtar LN.

J Infect Dis. 2022 Apr 22:jiac151. doi: 10.1093/infdis/jiac151. Online ahead of print.

A genome-wide CRISPR activation screen identifies PRRX2 as a regulator of enzalutamide resistance in prostate cancer.

Rodríguez Y, Unno K, Truica MI, Chalmers ZR, Yoo YA, Vatapalli R, Sagar V, Yu J, Lysy B, Hussain M, Han H, Abdulkadir SA.

Cancer Res. 2022 Apr 11:canres.3565.2021. doi: 10.1158/0008-5472.CAN-21-3565. Online ahead of print.

SPOROS: A pipeline to analyze DISE/6mer seed toxicity.

Bartom ET, Kocherginsky M, Paudel B, Vaidyanathan A, Haluck-Kangas A, Patel M, O'Shea KL, Murmann AE, Peter ME.

PLoS Comput Biol. 2022 Mar 31;18(3):e1010022. doi: 10.1371/journal.pcbi.1010022. eCollection 2022 Mar.

Genome-wide Analysis Reflects Novel 5-Hydroxymethylcytosines Implicated in Diabetic Nephropathy and the Biomarker Potential.

Yang Y, Zeng C, Yang K, Xu S, Zhang Z, Cai Q, He C, Zhang W, Liu SM.

Extracell Vesicles Circ Nucl Acids. 2022;3(1):49-60. Epub 2022 Mar 24.

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