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Recent Publications

Browse recent studies from the Lou and Jean Malnati Brain Tumor Institute to learn more about our cutting-edge research.

  1. Rabin EE, Huang J, Kim M, Mozny A, Lauing KL, Penco-Campillo M, Zhai L, Bommi P, Mi X, Power EA  et al.  Age-stratified comorbid and pharmacologic analysis of patients with glioblastoma.  Brain Behav Immun Health  2024 Jul;38:100753. pii:100753
  2. Kumthekar P, Lyleroehr M, Lacson L, Lukas RV, Dixit K, Stupp R, Kruser T, Raizer J, Hou A, Sachdev S  et al.  A qualitative evaluation of factors influencing Tumor Treating fields (TTFields) therapy decision making among brain tumor patients and physicians.  BMC Cancer  2024 Apr 25;24(1):527. doi:10.1186/s12885-024-12042-x
  3. Zhang Q, Gao S, Li B, Li Q, Li X, Cheng J, Peng Z, Liang J, Zhang K, Hai J  et al.  Lithium-Doped Titanium Dioxide-Based Multilayer Hierarchical Structure for Accelerating Nerve-Induced Bone Regeneration.  ACS Appl Mater Interfaces  2024 Apr 25;. doi:10.1021/acsami.4c01520
  4. Song X, Tiek D, Miki S, Huang T, Lu M, Goenka A, Iglesia RP, Yu X, Wu R, Walker MN  et al.  RNA splicing analysis deciphers developmental hierarchies and reveals therapeutic targets in adult glioma.  J Clin Invest  2024 Apr 25;. pii:e173789
  5. Shireman JM, White Q, Ni Z, Mohanty C, Cai Y, Zhao L, Agrawal N, Gonugunta N, Wang X, Mccarthy L  et al.  Genomic analysis of human brain metastases treated with stereotactic radiosurgery reveals unique signature based on treatment failure.  iScience  2024 Apr 19;27(4):109601. pii:109601
  6. Zhang S, Zhang T, Cao G, Zhou J, He Z, Li X, Ren Y, Liu T, Jiang X, Guo L  et al.  Species -shared and -unique gyral peaks on human and macaque brains.  Elife  2024 Apr 18;12. pii:RP90182
  7. Habashy KJ, Dmello C, Chen L, Arrieta VA, Kim KS, Gould A, Youngblood MW, Bouchoux G, Burdett KB, Zhang H  et al.  Paclitaxel and Carboplatin in Combination with Low-intensity Pulsed Ultrasound for Glioblastoma.  Clin Cancer Res  2024 Apr 15;30(8):1619-1629. doi:10.1158/1078-0432.CCR-23-2367
  8. Zhang QS, Hayes JP, Gondi V, Pollack SM  Immunotherapy and Radiotherapy Combinations for Sarcoma.  Semin Radiat Oncol  2024 Apr;34(2):229-242. doi:10.1016/j.semradonc.2023.12.005
  9. Li X, Lu S, Ge L, Li Z, Chen R, Zu Y, Fu R, Li L, Wang C  Repetitive Transcranial Magnetic Stimulation Combined with Sling Exercise Modulates the Motor Cortex in Patients with Chronic Low Back Pain.  Neuroscience  2024 Mar 21;545:196-206. doi:10.1016/j.neuroscience.2024.03.011
  10. Budhiraja S, McManus G, Baisiwala S, Perrault EN, Cho S, Saathoff M, Chen L, Park CH, Kazi HA, Dmello C  et al.  ARF4-mediated retrograde trafficking as a driver of chemoresistance in GBM.  Neuro Oncol  2024 Mar 20;. pii:noae059
  11. Benedetti DJ, Varela CR, Renfro LA, Tornwall B, Dix DB, Ehrlich PF, Glick RD, Kalapurakal J, Perlman E, Gratias E  et al.  Treatment of children with favorable histology Wilms tumor with extrapulmonary metastases: A report from the COG studies AREN0533 and AREN03B2 and NWTSG study NWTS-5.  Cancer  2024 Mar 15;130(6):947-961. doi:10.1002/cncr.35099
  12. Khan F, Lin Y, Ali H, Pang L, Dunterman M, Hsu WH, Frenis K, Grant Rowe R, Wainwright DA, McCortney K  et al.  Lactate dehydrogenase A regulates tumor-macrophage symbiosis to promote glioblastoma progression.  Nat Commun  2024 Mar 05;15(1):1987. pii:1987
  13. Randall J, Sachdev S  A valuable glioblastoma prognostic marker driven by radiosensitivity.  Neuro Oncol  2024 Mar 04;26(3):514-515. doi:10.1093/neuonc/noad266
  14. Rastogi A, Brugnara G, Foltyn-Dumitru M, Mahmutoglu MA, Preetha CJ, Kobler E, Pflüger I, Schell M, Deike-Hofmann K, Kessler T  et al.  Deep-learning-based reconstruction of undersampled MRI to reduce scan times: a multicentre, retrospective, cohort study.  Lancet Oncol  2024 Mar;25(3):400-410. doi:10.1016/S1470-2045(23)00641-1
  15. Evageliou N, Renfro LA, Geller J, Perlman E, Kalapurakal J, Paulino A, Dix D, Eklund MJ, Murphy AJ, Romao RLP  et al.  Prognostic impact of lymph node involvement and loss of heterozygosity of 1p or 16q in stage III favorable histology Wilms tumor: A report from Children's Oncology Group Studies AREN03B2 and AREN0532.  Cancer  2024 Mar 01;130(5):792-802. doi:10.1002/cncr.35084
  16. Nandoliya KR, Thirunavu V, Ellis E, Dixit K, Tate MC, Drumm MR, Templer JW  Pre-operative predictors of post-operative seizure control in low-grade glioma: a systematic review and meta-analysis.  Neurosurg Rev  2024 Feb 27;47(1):94. doi:10.1007/s10143-024-02329-9
  17. Peters KB, Templer J, Gerstner ER, Wychowski T, Storstein AM, Dixit K, Walbert T, Melnick K, Hrachova M, Partap S  et al.  Discontinuation of Antiseizure Medications in Patients With Brain Tumors.  Neurology  2024 Feb 27;102(4):e209163. doi:10.1212/WNL.0000000000209163
  18. Wang YZ, Castillon CCM, Gebis KK, Bartom ET, d'Azzo A, Contractor A, Savas JN  Notch receptor-ligand binding facilitates extracellular vesicle-mediated neuron-to-neuron communication.  Cell Rep  2024 Feb 27;43(2):113680. doi:10.1016/j.celrep.2024.113680
  19. Benedetti DJ, Renfro LA, Tfirn I, Daw NC, Kalapurakal JA, Ehrlich PF, Khanna G, Perlman E, Warwick A, Gow KW  et al.  Treatment and outcomes of clear cell sarcoma of the kidney: A report from the Children's Oncology Group studies AREN0321 and AREN03B2.  Cancer  2024 Feb 23;. doi:10.1002/cncr.35266
  20. Carpentier A, Stupp R, Sonabend AM, Dufour H, Chinot O, Mathon B, Ducray F, Guyotat J, Baize N, Menei P  et al.  Repeated blood-brain barrier opening with a nine-emitter implantable ultrasound device in combination with carboplatin in recurrent glioblastoma: a phase I/II clinical trial.  Nat Commun  2024 Feb 23;15(1):1650. pii:1650
  21. Kudruk S, Forsyth CM, Dion MZ, Hedlund Orbeck JK, Luo J, Klein RS, Kim AH, Heimberger AB, Mirkin CA, Stegh AH  et al.  Multimodal neuro-nanotechnology: Challenging the existing paradigm in glioblastoma therapy.  Proc Natl Acad Sci U S A  2024 Feb 20;121(8):e2306973121. pii:e2306973121
  22. Tripathi S, Najem H, Dussold C, Pacheco S, Miska J, McCortney K, Steffens A, Walshon J, Winkowski D, Cloney M  et al.  Cancer-associated fibroblast-secreted collagen is associated with immune inhibitor receptor LAIR1 in gliomas.  J Clin Invest  2024 Feb 15;134(4). pii:e176613
  23. Arrillaga-Romany I, Gardner SL, Odia Y, Aguilera D, Allen JE, Batchelor T, Butowski N, Chen C, Cloughesy T, Cluster A  et al.  ONC201 (Dordaviprone) in Recurrent H3 K27M-Mutant Diffuse Midline Glioma.  J Clin Oncol  2024 Feb 09;:JCO2301134. doi:10.1200/JCO.23.01134
  24. Kim DR, Orr MJ, Yu X, Munshi HH, Wang A, Trudeau C, Kwong AJ, Cheng SY, Scheidt KA  Synthesis and Structural Optimization of ATG4B Inhibitors for the Attenuation of Autophagy in Glioblastoma.  ACS Med Chem Lett  2024 Feb 08;15(2):258-264. doi:10.1021/acsmedchemlett.3c00505
  25. Li J, Shih LK, Brat DJ  Integrated Proteogenomics Uncover Mechanisms of Glioblastoma Evolution, Pointing to Novel Therapeutic Targets.  Cancer Res  2024 Feb 08;. doi:10.1158/0008-5472.CAN-24-0452
  26. Moscona-Nissan A, Habashy KJ, Arrieta VA, Sonabend AM, Dmello C  Combining causal and correlative approaches to discover biomarkers of response to paclitaxel.  Oncotarget  2024 Feb 08;15:117-122. doi:10.18632/oncotarget.28549
  27. Collado J, Boland L, Ahrendsen JT, Miska J, Lee-Chang C  Understanding the glioblastoma tumor microenvironment: leveraging the extracellular matrix to increase immunotherapy efficacy.  Front Immunol  2024;15:1336476. pii:1336476
  28. Zhang S, Zhang T, Cao G, Zhou J, He Z, Li X, Ren Y, Liu T, Jiang X, Guo L  et al.  Species -Shared and -Unique Gyral Peaks on Human and Macaque Brains.  bioRxiv  2024 Feb 05;. pii:2023.07.26.550760
  29. Driscoll RK, Lyne SB, Voce DJ, Maraka S, Gondi V, Chmura SJ, Dixit KS, Kumthekar PU, Karrison TG, Pytel P  et al.  A multi-institutional phase I study of acetazolamide with temozolomide in adults with newly diagnosed MGMT-methylated malignant glioma.  Neurooncol Adv  2024;6(1):vdae014. pii:vdae014
  30. Schwartz C, Rautalin I, Grauvogel J, Bissolo M, Masalha W, Steiert C, Schnell O, Beck J, Ebel F, Bervini D  et al.  Surgical Outcome of Patients With Supratentorial Meningiomas Aged 80 Years or Older-Retrospective International Multicenter Study.  Neurosurgery  2024 Feb 01;94(2):399-412. doi:10.1227/neu.0000000000002673
  31. Cherng HR, Qu M, Zafari Z, Bentzen S, Armstrong TS, Gondi V, Brown PD, Mehta M, Mishra MV  Evaluating the sensitivity of EQ-5D-5L in patients with brain metastases: a secondary analysis of NRG CC001.  J Natl Cancer Inst  2024 Jan 27;. pii:djae020
  32. Zheng S, Rammohan N, Sita T, Teo PT, Wu Y, Lesniak M, Sachdev S, Thomas TO  GlioPredictor: a deep learning model for identification of high-risk adult IDH-mutant glioma towards adjuvant treatment planning.  Sci Rep  2024 Jan 25;14(1):2126. pii:2126
  33. Pandey S, Cholak ME, Yadali R, Sosman JA, Tetreault MP, Fang D, Pollack SM, Gnjatic S, Obeng RC, Lyerly HK  et al.  Immune Assessment Today: Optimizing and Standardizing Efforts to Monitor Immune Responses in Cancer and Beyond.  Cancers (Basel)  2024 Jan 23;16(3). pii:475
  34. Khazanchi R, Nandoliya KR, Shahin MN, Rae AI, Chaliparambil RK, Bowden SG, Alwakeal A, Lopez Ramos CG, Stedelin B, Youngblood MW  et al.  Obesity and meningioma: a US population-based study paired with analysis of a multi-institutional cohort.  J Neurosurg  2024 Jan 19;:1-10. doi:10.3171/2023.11.JNS23732
  35. Paudel B, Jeong SY, Martinez CP, Rickman A, Haluck-Kangas A, Bartom ET, Fredriksen K, Affaneh A, Kessler JA, Mazzulli JR  et al.  Death Induced by Survival gene Elimination (DISE) correlates with neurotoxicity in Alzheimer's disease and aging.  Nat Commun  2024 Jan 18;15(1):264. pii:264
  36. Chia TY, Billingham LK, Boland L, Katz JL, Arrieta VA, Shireman J, Rosas AL, DeLay SL, Zillinger K, Geng Y  et al.  The CXCL16-CXCR6 axis in glioblastoma modulates T-cell activity in a spatiotemporal context.  Front Immunol  2023;14:1331287. pii:1331287
  37. Arrieta VA, Duerinck J, Burdett KB, Habashy KJ, Geens W, Gould A, Schwarze JK, Dmello C, Kim KS, Saganty R  et al.  ERK1/2 Phosphorylation Predicts Survival in Recurrent Glioblastoma Following Intracerebral and Adjuvant PD-1/CTLA-4 Immunotherapy: A REMARK-guided Analysis.  Clin Cancer Res  2024 Jan 17;30(2):379-388. doi:10.1158/1078-0432.CCR-23-1889
  38. Romay MC, Knutsen RH, Ma F, Mompeón A, Hernandez GE, Salvador J, Mirkov S, Batra A, Sullivan DP, Procissi D  et al.  Age-related loss of Notch3 underlies brain vascular contractility deficiencies, glymphatic dysfunction, and neurodegeneration in mice.  J Clin Invest  2024 Jan 16;134(2). pii:e166134
  39. Hou D, Wan H, Katz JL, Wang S, Castro BA, Vazquez-Cervantes GI, Arrieta VA, Dhiantravan S, Najem H, Rashidi A  et al.  Antigen-presenting B cells promote TCF-1+ PD1- stem-like CD8+ T-cell proliferation in glioblastoma.  Front Immunol  2023;14:1295218. pii:1295218
  40. Tripathi S, Nathan CL, Tate MC, Horbinski CM, Templer JW, Rosenow JM, Sita TL, James CD, Deneen B, Miller SD  et al.  The immune system and metabolic products in epilepsy and glioma-associated epilepsy: emerging therapeutic directions.  JCI Insight  2024 Jan 09;9(1). pii:e174753
  41. Bhutada I, Khambati F, Cheng SY, Tiek DM, Duckett D, Lawrence H, Vogelbaum MA, Mo Q, Chellappan SP, Padmanabhan J  CDK7 and CDK9 inhibition interferes with transcription, translation, and stemness, and induces cytotoxicity in GBM irrespective of temozolomide sensitivity.  Neuro Oncol  2024 Jan 05;26(1):70-84. doi:10.1093/neuonc/noad143
  42. Rashidi A, Billingham LK, Zolp A, Chia TY, Silvers C, Katz JL, Park CH, Delay S, Boland L, Geng Y  et al.  Myeloid cell-derived creatine in the hypoxic niche promotes glioblastoma growth.  Cell Metab  2024 Jan 02;36(1):62-77.e8. doi:10.1016/j.cmet.2023.11.013
  43. Pawlowski KD, Duffy JT, Gottschalk S, Balyasnikova IV  Cytokine Modification of Adoptive Chimeric Antigen Receptor Immunotherapy for Glioblastoma.  Cancers (Basel)  2023 Dec 15;15(24). pii:5852
  44. Fares J, Petrosyan E, Kanojia D, Dmello C, Cordero A, Duffy JT, Yeeravalli R, Sahani MH, Zhang P, Rashidi A  et al.  Metixene is an incomplete autophagy inducer in preclinical models of metastatic cancer and brain metastases.  J Clin Invest  2023 Dec 15;133(24). pii:e161142
  45. Cherng HR, Sun K, Bentzen S, Armstrong TS, Gondi V, Brown PD, Mehta M, Mishra MV  Evaluating the Heterogeneity of Hippocampal Avoidant Whole Brain Radiotherapy Treatment Effect: A Secondary Analysis of NRG CC001.  Neuro Oncol  2023 Dec 09;. pii:noad226
  46. Sadagopan NS, Nandoliya KR, Youngblood MW, Horbinski CM, Ahrendsen JT, Magill ST  A novel BRAF::PTPRN2 fusion in meningioma: a case report.  Acta Neuropathol Commun  2023 Dec 08;11(1):194. pii:194
  47. Chen WC, Choudhury A, Youngblood MW, Polley MC, Lucas CG, Mirchia K, Maas SLN, Suwala AK, Won M, Bayley JC  et al.  Targeted gene expression profiling predicts meningioma outcomes and radiotherapy responses.  Nat Med  2023 Dec;29(12):3067-3076. doi:10.1038/s41591-023-02586-z
  48. Primdahl D, Cohen-Nowak A, Kumthekar P  Novel approaches to treatment of leptomeningeal metastases.  Curr Opin Neurol  2023 Dec 01;36(6):592-602. doi:10.1097/WCO.0000000000001218
  49. Lukas RV, Horbinski C  Glioma Response to IDH Inhibition: Real-World Experience.  Clin Cancer Res  2023 Dec 01;29(23):4709-4710. doi:10.1158/1078-0432.CCR-23-2164
  50. Johnson M, Bell A, Lauing KL, Ladomersky E, Zhai L, Penco-Campillo M, Shah Y, Mauer E, Xiu J, Nicolaides T  et al.  Advanced Age in Humans and Mouse Models of Glioblastoma Show Decreased Survival from Extratumoral Influence.  Clin Cancer Res  2023 Dec 01;29(23):4973-4989. doi:10.1158/1078-0432.CCR-23-0834
These are the publications from our team members that have been most recently indexed by PubMed. Visit PubMed to see more of our publications.

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