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Clinical Trials

Clinical and outcomes research under the direction of the Asher Center for the Study and Treatment of Depressive Disorders is conducted both at the Northwestern University Feinberg School of Medicine and Northwestern Medicine clinics.

For more information about the research or participation, please call us at 1-855-99-ASHER.

Feinberg Clinical Trials

Scientists at the medical school are conducting hundreds of clinical trials daily. More information about our work, including a Volunteer FAQ, is available via the Feinberg Office of Research Clinical Trials page.

Trials
Randomized Controlled Trial of a Mindfulness-based Intervention in a Federally Qualified Center (FQHC)
Northwestern University and Near North Health are currently recruiting participants for a research study to understand if mind and body approaches such as breathing techniques, mindfulness meditatio…
Northwestern University and Near North Health are currently recruiting participants for a research study to understand if mind and body approaches such as breathing techniques, mindfulness meditation, and gentle yoga work to improve stress. Up to $110 in compensation for full participation! Participants will either be assigned to receive an 8-week, 90 min per session group or to the wellness check-in group. For more info, please call 773-683-1275.

Inclusion Criteria:

  • 18-65 years old
  • at least mild depressive symptoms
  • English speaking
Burnett-Zeigler, Inger EBurnett-Zeigler, Inger E
NCT03620721 STU00207126
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Zhou, Elayne
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PK and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants
We are interested in studying drugs commonly prescribed to women who are breastfeeding so we can learn more about the amount of drug that is transferred to breastmilk and estimate how much of that drug is consumed by breast…
We are interested in studying drugs commonly prescribed to women who are breastfeeding so we can learn more about the amount of drug that is transferred to breastmilk and estimate how much of that drug is consumed by breastfed infants.
Wisner, Katherine LeahWisner, Katherine Leah
  • Map it 676 N. St. Clair St.
    Chicago, IL
STU00208328
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DEFINING FACTORS RESPONSIBLE FOR TEMPORAL CHANGES IN CYP3A4-MEDIATED DRUG METABOLISM DURING PREGNANCY

The purpose of this research is to understand changes in a woman’s body during pregnancy, specifically how the body processes medication during pregnancy. We know that over 90% of women take at…

The purpose of this research is to understand changes in a woman’s body during pregnancy, specifically how the body processes medication during pregnancy. We know that over 90% of women take at least one drug during pregnancy. These changes in a pregnant women’s body may change how medications are metabolized or broken down by the body.

Genetics can influence how the body metabolizes or breaks down medications. This study will be examining the up-regulation, or “speeding up” of a gene called CYP3A4. This gene helps the body process quetiapine, a mood-stabilizing drug commonly used to treat bipolar disorder, schizophrenia, depression, and sleep issues like insomnia.

The goal of our research is to understand how drug metabolism changes across pregnancy and how enzymes in the liver work to up-regulate or “speed up” the CYP3A4 gene during pregnancy. Current dosage guidelines do not take into consideration these possible changes in pregnancy that may affect how well a medication may work for a pregnant women. This research will help us predict how drug metabolism changes and improve medication dosage guidelines for pregnant women in the future. This is important because it will allow us to minimize the risk of over- and under-dosing pregnant women.

Wisner, Katherine LeahWisner, Katherine Leah
  • Map it 676 N. St. Clair St.
    Chicago, IL
STU00211088
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African-American Social Support Effectiveness Treatment-Partners alleviating Perinatal Depression (ASSET-PPD)
You are invited to participate in a research study at Northwestern University that provides skills and training to fathers who have a partner with prenatal depression. The research study aims…
You are invited to participate in a research study at Northwestern University that provides skills and training to fathers who have a partner with prenatal depression. The research study aims to give guidance on how fathers can optimize their support of their partner during this difficult time. ALL SESSIONS WILL BE VIRTUAL. 

-Pregnant African-American mother and male partner

-Available to begin study in 2nd trimester

-Mother in treatment for depression with current symptoms

-Parents are 18 y/o or older

Fisher, Sheehan DavidFisher, Sheehan David
STU00212595
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