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Northwestern University Feinberg School of Medicine
Research

High-Impact- Factor Research 2019

Barthel FP, Johnson KC, Varn FS, Moskalik AD, Tanner G, Kocakavuk E, Anderson KJ, Abiola O, Aldape K, Alfaro KD, Alpar D, Amin SB, Ashley DM, Bandopadhayay P, Barnholtz-Sloan JS, Beroukhim R, Bock C, Brastianos PK, Brat DJ, Brodbelt AR, Bruns AF, Bulsara KR, Chakrabarty A, Chakravarti A, Chuang JH, Claus EB, Cochran EJ, Connelly J, Costello JF, Finocchiaro G, Fletcher MN, French PJ, Gan HK, Gilbert MR, Gould PV, Grimmer MR, Iavarone A, Ismail A, Jenkinson MD, Khasraw M, Kim H, Kouwenhoven MCM, LaViolette PS, Li M, Lichter P, Ligon KL, Lowman AK, Malta TM, Mazor T, McDonald KL, Molinaro AM, Nam DH, Nayyar N, Ng HK, Ngan CY, Niclou SP, Niers JM, Noushmehr H, Noorbakhsh J, Ormond DR, Park CK, Poisson LM, Rabadan R, Radlwimmer B, Rao G, Reifenberger G, Sa JK, Schuster M, Shaw BL, Short SC, Smitt PAS, Sloan AE, Smits M, Suzuki H, Tabatabai G, Van Meir EG, Watts C, Weller M, Wesseling P, Westerman BA, Widhalm G, Woehrer A, Yung WKA, Zadeh G, Huse JT, De Groot JF, Stead LF, Verhaak RGW. Longitudinal molecular trajectories of diffuse glioma in adults. Nature. 2019 Dec;576(7785):112-120.

Bostick JW, Wang Y, Shen Z, Ge Y, Brown J, Chen ZE, Mohamadzadeh M, Fox JG, Zhou L. Dichotomous regulation of group 3 innate lymphoid cells by nongastric Helicobacter species. Proceedings of the National Academy of Sciences of the United States of America. 2019 Dec 3;116(49):24760-24769.

Butler J, Packer M, Greene SJ, Fiuzat M, Anker SD, Anstrom KJ, Carson PE, Cooper LB, Fonarow GC, Hernandez AF, Januzzi JL, Jr., Jessup M, Kalyani RR, Kaul S, Kosiborod M, Lindenfeld J, McGuire DK, Sabatine MS, Solomon SD, Teerlink JR, Vaduganathan M, Yancy CW, Stockbridge N, O'Connor CM. Heart Failure End Points in Cardiovascular Outcome Trials of Sodium Glucose Cotransporter 2 Inhibitors in Patients With Type 2 Diabetes Mellitus: A Critical Evaluation of Clinical and Regulatory Issues. Circulation. 2019 Dec 17;140(25):2108-2118.

Coleman RL, Fleming GF, Brady MF, Swisher EM, Steffensen KD, Friedlander M, Okamoto A, Moore KN, Efrat Ben-Baruch N, Werner TL, Cloven NG, Oaknin A, DiSilvestro PA, Morgan MA, Nam JH, Leath CA, 3rd, Nicum S, Hagemann AR, Littell RD, Cella D, Baron-Hay S, Garcia-Donas J, Mizuno M, Bell-McGuinn K, Sullivan DM, Bach BA, Bhattacharya S, Ratajczak CK, Ansell PJ, Dinh MH, Aghajanian C, Bookman MA. Veliparib with First-Line Chemotherapy and as Maintenance Therapy in Ovarian Cancer. New England Journal of Medicine. 2019 Dec 19;381(25):2403-2415.

Cuddy LK, Wani WY, Morella ML, Pitcairn C, Tsutsumi K, Fredriksen K, Justman CJ, Grammatopoulos TN, Belur NR, Zunke F, Subramanian A, Affaneh A, Lansbury PT, Mazzulli JR. Stress-Induced Cellular Clearance Is Mediated by the SNARE Protein ykt6 and Disrupted by alpha-Synuclein. Neuron. 2019 Dec;104(5):869.

Dransfield MT, Voelker H, Bhatt SP, Brenner K, Casaburi R, Come CE, Cooper JAD, Criner GJ, Curtis JL, Han MK, Hatipoglu U, Helgeson ES, Jain VV, Kalhan R, Kaminsky D, Kaner R, Kunisaki KM, Lambert AA, Lammi MR, Lindberg S, Make BJ, Martinez FJ, McEvoy C, Panos RJ, Reed RM, Scanlon PD, Sciurba FC, Smith A, Sriram PS, Stringer WW, Weingarten JA, Wells JM, Westfall E, Lazarus SC, Connett JE. Metoprolol for the Prevention of Acute Exacerbations of COPD. New England Journal of Medicine. 2019 Dec 12;381(24):2304-2314.

Ghosal D, Kim KW, Zheng H, Kaplan M, Truchan HK, Lopez AE, McIntire IE, Vogel JP, Cianciotto NP, Jensen GJ In vivo structure of the Legionella type II secretion system by electron cryotomography. Nature Microbiology. 2019 Dec; 4(12): 2101-2108.

Gur-Cohen S, Yang H, Baksh SC, Miao YX, Levorse J, Kataru RP, Liu XL, de la Cruz-Racelis J, Mehrara BJ, Fuchs E. Stem cell-driven lymphatic remodeling coordinates tissue regeneration. Science. 2019 Dec;366(6470):1218.

Gutruf P, Yin RT, Lee KB, Ausra J, Brennan JA, Qiao Y, Xie ZQ, Peralta R, Talarico O, Murillo A, Chen SW, Leshock JP, Haney CR, Waters EA, Zhang CX, Luan HW, Huang YG, Trachiotis G, Efimov IR, Rogers JA. Wireless, battery-free, fully implantable multimodal and multisite pacemakers for applications in small animal models. Nature Communications. 2019 Dec;10.

Hunt RJ, Granat L, McElroy GS, Ranganathan R, Chandel NS, Bateman JM. Mitochondrial stress causes neuronal dysfunction via an ATF4-dependent increase in L-2-hydroxyglutarate. Journal of Cell Biology. 2019 Dec;218(12):4007-4016.

Kitkungvan D, Yang EY, El Tallawi KC, Nagueh SF, Nabi F, Khan MA, Nguyen DT, Graviss EA, Lawrie GM, Zoghbi WA, Bonow RO, Quinones MA, Shah DJ. Prognostic Implications of Diffuse Interstitial Fibrosis in Asymptomatic Primary Mitral Regurgitation. Circulation. 2019 Dec 17;140(25):2122-2124.

Kollef MH, Novacek M, Kivistik U, Rea-Neto A, Shime N, Martin-Loeches I, Timsit JF, Wunderink RG, Bruno CJ, Huntington JA, Lin G, Yu B, Butterton JR, Rhee EG. Ceftolozane-tazobactam versus meropenem for treatment of nosocomial pneumonia (ASPECT-NP): a randomised, controlled, double-blind, phase 3, non-inferiority trial. Lancet Infectious Diseases. 2019 Dec;19(12):1299-1311.

Lafaille FG, Harschnitz O, Lee YS, Zhang P, Hasek ML, Kerner G, Itan Y, Ewaleifoh O, Rapaport F, Carlile TM, Carter-Timofte ME, Paquet D, Dobbs K, Zimmer B, Gao DX, Rojas-Duran MF, Kwart D, Rattina V, Ciancanelli MJ, McAlpine JL, Lorenzo L, Boucherit S, Rozenberg F, Halwani R, Henry B, Amenzoui N, Alsum Z, Marques L, Church JA, Al-Muhsen S, Tardieu M, Bousfiha AA, Paludan SR, Mogensen TH, Quintana-Murci L, Tessier-Lavigne M, Smith GA, Notarangelo LD, Studer L, Gilbert W, Abel L, Casanova JL, Zhang SY. Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis. Nature Medicine. 2019 Dec;25(12):1873.

Lagae L, Sullivan J, Knupp K, Laux L, Polster T, Nikanorova M, Devinsky O, Cross JH, Guerrini R, Talwar D, Miller I, Farfel G, Galer BS, Gammaitoni A, Mistry A, Morrison G, Lock M, Agarwal A, Lai WW, Ceulemans B, Gill D, Riney K, Scheffer I, Buchhalter J, Carmant L, Connolly M, Nabbout R, Brandt U, Jacobs-LeVan J, Mayer T, Panzer A, Pringsheim M, Stephani U, Wolff M, Battaglia D, Beccaria F, Dana F, Granata T, Romeo A, Striano P, Vigevano F, Gil-Nagel A, San Antonio V, Sanchez-Carpintero R, Desurkar A, Hughes E, Lyer A, Philip S, Zuberi S, Sharp G, Berenson F, Faux L, Marsh E, Nespeca M, Nahouraii R, Paolicdii J, Phillips S, Perry MS, Poduri A, Renfroe B, Saneto R, Shahid A, Smith D, de Menezes MS, Sweney M, Thiele E, Wheless J, Wilfong A, Wirrell E, Zupanc M, Grp FADS. Fenfluramine hydrochloride for the treatment of seizures in Dravet syndrome: a randomised, double-blind, placebo-controlled trial. Lancet. 2019 Dec;394(10216):2243-2254.

Lambo S, Grobner SN, Rausch T, Waszak SM, Schmidt C, Gorthi A, Romero JC, Mauermann M, Brabetz S, Krausert S, Buchhalter I, Koster J, Zwijnenburg DA, Sill M, Hubner JM, Mack N, Schwalm B, Ryzhova M, Hovestadt V, Papillon-Cavanagh S, Chan JA, Landgraf P, Ho B, Milde T, Witt O, Ecker J, Sahm F, Sumerauer D, Ellison DW, Orr BA, Darabi A, Haberler C, Figarella-Branger D, Wesseling P, Schittenhelm J, Remke M, Taylor MD, Gil-da-Costa MJ, Lastowska M, Grajkowska W, Hasselblatt M, Hauser P, Pietsch T, Uro-Coste E, Bourdeaut F, Masliah-Planchon J, Rigau V, Alexandrescu S, Wolf S, Li XN, Schuller U, Snuderl M, Karajannis MA, Giangaspero F, Jabado N, von Deimling A, Jones DTW, Korbel JO, von Hoff K, Lichter P, Huang A, Bishop AJR, Pfister SM, Korshunov A, Kool M. The molecular landscape of ETMR at diagnosis and relapse.Nature. 2019 Dec;576(7786):274.

Mercey O, Levine MS, LoMastro GM, Rostaing P, Brotslaw E, Gomez V, Kumar A, Spassky N, Mitchell BJ, Meunier A, Holland AJ. Massive centriole production can occur in the absence of deuterosomes in multiciliated cells. Nature Cell Biology. 2019 Dec;21(12):1544.

Owen JL, Kibbi N, Worley B, Kelm RC, Wang JV, Barker CA, Behshad R, Bichakjian CK, Bolotin D, Bordeaux JS, Bradshaw SH, Cartee TV, Chandra S, Cho NL, Choi JN, Council ML, Demirci H, Eisen DB, Esmaeli B, Golda N, Huang CC, Ibrahim SF, Jiang SB, Kim J, Kuzel TM, Lai SY, Lawrence N, Lee EH, Leitenberger JJ, Maher IA, Mann MW, Minkis K, Mittal BB, Nehal KS, Neuhaus IM, Ozog DM, Petersen B, Rotemberg V, Samant S, Samie FH, Servaes S, Shields CL, Shin TM, Sobanko JF, Somani AK, Stebbins WG, Thomas JR, Thomas VD, Tse DT, Waldman AH, Wong MK, Xu YG, Yu SS, Zeitouni NC, Ramsay T, Reynolds KA, Poon E, Alam M. Sebaceous carcinoma: evidence-based clinical practice guidelines. Lancet Oncology. 2019 Dec;20(12):E699-E714.

Owens DK, Davidson KW, Krist AH, Barry MJ, Cabana M, Caughey AB, Doubeni CA, Epling JW, Jr., Kubik M, Landefeld CS, Mangione CM, Pbert L, Silverstein M, Simon MA, Tseng CW, Wong JB. Screening for Abdominal Aortic Aneurysm: US Preventive Services Task Force Recommendation Statement. JAMA. 2019 Dec 10;322(22):2211-2218.

Patteson AE, Vahabikashi A, Pogoda K, Adam SA, Mandal K, Kittisopikul M, Sivagurunathan S, Goldman A, Goldman RD, Janmey PA. Vimentin protects cells against nuclear rupture and DNA damage during migration. Journal of Cell Biology. 2019 Dec 2;218(12):4079-4092.

Reeder JT, Xue YG, Franklin D, Deng YJ, Choi J, Prado O, Kim R, Liu C, Hanson J, Ciraldo J, Bandodkar AJ, Krishnan S, Johnson A, Patnaude E, Avila R, Huang YG, Rogers JA. Resettable skin interfaced microfluidic sweat collection devices with chemesthetic hydration feedback. Nature Communications. 2019 Dec;10.

Vahabikashi A, Gelman A, Dong BQ, Gong LH, Cha EDK, Schimmel M, Tamm ER, Perkumas K, Stamer WD, Sun C, Zhang HF, Gong HY, Johnson M. Increased stiffness and flow resistance of the inner wall of Schlemm's canal in glaucomatous human eyes. Proceedings of the National Academy of Sciences of the United States of America. 2019;116(52):26555-26563.

Welsh JD, Hoofnagle MH, Bamezai S, Oxendine M, Lim L, Hall JD, Yang J, Schultz S, Engel JD, Kume T, Oliver G, Jimenez JM, Kahn ML. Hemodynamic regulation of perivalvular endothelial gene expression prevents deep venous thrombosis. Journal of Clinical Investigation. 2019 Dec;129(12):5489-5500.

Younossi ZM, Ratziu V, Loomba R, Rinella M, Anstee QM, Goodman Z, Bedossa P, Geier A, Beckebaum S, Newsome PN, Sheridan D, Sheikh MY, Trotter J, Knapple W, Lawitz E, Abdelmalek MF, Kowdley KV, Montano-Loza AJ, Boursier J, Mathurin P, Bugianesi E, Mazzella G, Olveira A, Cortez-Pinto H, Graupera I, Orr D, Gluud LL, Dufour JF, Shapiro D, Campagna J, Zaru L, MacConell L, Shringarpure R, Harrison S, Sanyal AJ, Investigators RS. Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial. Lancet. 2019 Dec;394(10215):2184-2196.

Ysselstein D, Nguyen M, Young TJ, Severino A, Schwake M, Merchant K, Krainc D. LRRK2 kinase activity regulates lysosomal glucocerebrosidase in neurons derived from Parkinson's disease patients. Nature Communications. 2019 Dec;10.

Zanatta G, Sula A, Miles AJ, Ng LCT, Torella R, Pryde DC, DeCaen PG, Wallace BA. Valproic acid interactions with the NavMs voltage-gated sodium channel. Proceedings of the National Academy of Sciences of the United States of America. 2019;116(52):26549-26554.

Agarwal N, McQuarrie K, Bjartell A, Chowdhury S, Gomes A, Chung BH, Ozguroglu M, Soto AJ, Merseburger AS, Uemura H, Ye DW, Given R, Cella D, Basch E, Miladinovic B, Dearden L, Deprince K, Naini V, Lopez-Gitlitz A, Chi KN, Investigators T. Health-related quality of life after apalutamide treatment in patients with metastatic castration-sensitive prostate cancer (TITAN): a randomised, placebo-controlled, phase 3 study. Lancet Oncology. 2019 Nov;20(11):1518-1530.

Bueno MJ, Jimenez-Renard V, Samino S, Capellades J, Junza A, Lopez-Rodriguez ML, Garcia-Carceles J, Lopez-Fabuel I, Bolanos JP, Chandel NS, Yanes O, Colomer R, Quintela-Fandino M. Essentiality of fatty acid synthase in the 2D to anchorage-independent growth transition in transforming cells. Nature Communications. 2019 Nov;10:18.

Chun E, Lavoie S, Fonseca-Pereira D, Bae S, Michaud M, Hoveyda HR, Fraser GL, Comeau CAG, Glickman JN, Fuller MH, Layden BT, Garrett WS. Metabolite-Sensing Receptor Ffar2 Regulates Colonic Group 3 Innate Lymphoid Cells and Gut Immunity.Immunity. 2019 Nov;51(5):871

Coffey EBJ, Nicol T, White-Schwoch T, Chandrasekaran B, Krizman J, Skoe E, Zatorre RJ, Kraus N. Evolving perspectives on the sources of the frequency-following response.Nature Communications. 2019 Nov;10:10.

Demonbreun AR, Fallon KS, Oosterbaan CC, Bogdanovic E, Warner JL, Sell JJ, Page PG, Quattrocelli M, Barefield DY, McNally EM. Recombinant annexin A6 promotes membrane repair and protects against muscle injury. Journal of Clinical Investigation. 2019 Nov;129(11):4657-4670.

Deng F, Sharma I, Dai YB, Yang M, Kanwar YS.Myo-inositol oxygenase expression profile modulates pathogenic ferroptosis in the renal proximal tubule.Journal of Clinical Investigation. 2019 Nov;129(11):5033-5049.

Han HY, Jain AD, Truica MI, Izquierdo-Ferrer J, Anker JF, Lysy B, Sagar V, Luan Y, Chalmers ZR, Unno K, Mok H, Vatapalli R, Yoo YA, Rodriguez Y, Kandela I, Parker JB, Chakravarti D, Mishra RK, Schiltz GE, Abdulkadir SA. Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy. Cancer Cell. 2019 Nov;36(5):483.

He C, Danes JM, Hart PC, Zhu Y, Huang Y, de Abreu AL, O'Brien J, Mathison AJ, Tang B, Frasor JM, Wakefield LM, Ganini D, Stauder E, Zielonka J, Gantner BN, Urrutia RA, Gius D, Bonini MG. SOD2 acetylation on lysine 68 promotes stem cell reprogramming in breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 2019 Nov 19;116(47):23534-23541.

He Q, Arroyo ED, Smukowski SN, Xu J, Piochon C, Savas JN, Portera-Cailliau C, Contractor A. Critical period inhibition of NKCC1 rectifies synapse plasticity in the somatosensory cortex and restores adult tactile response maps in fragile X mice. Molecular Psychiatry. 2019 Nov;24(11):1732-1747.

Jibril L, Chen PC, Hu JT, Odom TW, Mirkin CA. Massively Parallel Nanoparticle Synthesis in Anisotropic Nanoreactors. Acs Nano. 2019 Nov;13(11):12408-12414.

Kaplan RM, Koehler J, Ziegler PD, Sarkar S, Zweibel S, Passman RS. Stroke Risk as a Function of Atrial Fibrillation Duration and CHA(2)DS(2)-VASc Score. Circulation. 2019 Nov;140(20):1639-1646.

Kightlinger W, Duncker KE, Ramesh A, Thames AH, Natarajan A, Stark JC, Yang A, Lin L, Mrksich M, DeLisa MP, Jewett MC. A cell-free biosynthesis platform for modular construction of protein glycosylation pathways. Nat Communications. 2019 Nov 27;10(1):5404.

Notomi S, Ishihara K, Efstathiou NE, Lee JJ, Hisatomi T, Tachibana T, Konstantinou EK, Ueta T, Murakami Y, Maidana DE, Ikeda Y, Kume S, Terasaki H, Sonoda S, Blanz J, Young L, Sakamoto T, Sonoda KH, Saftig P, Ishibashi T, Miller JW, Kroemer G, Vavvas DG. Genetic LAMP2 deficiency accelerates the age-associated formation of basal laminar deposits in the retina. Proceedings of the National Academy of Sciences of the United States of America. 2019 Nov 19;116(47):23724-23734.

Parker WF, Anderson AS, Gibbons RD, Garrity ER, Ross LF, Huang ES, Churpek MM. Association of Transplant Center With Survival Benefit Among Adults Undergoing Heart Transplant in the United States. JAMA-Journal of the American Medical Association. 2019 Nov;322(18):1789-1798.

Pawlak JB, Balint L, Lim L, Ma WS, Davis RB, Benyo Z, Soares MJ, Oliver G, Kahn ML, Jakus Z, Caron KM. Lymphatic mimicry in maternal endothelial cells promotes placental spiral artery remodeling. Journal of Clinical Investigation. 2019 Nov;129(11):4912-4921.

Quagliarini F, Mir AA, Balazs K, Wierer M, Dyar KA, Jouffe C, Makris K, Hawe J, Heinig M, Filipp FV, Barish GD, Uhlenhaut NH. Cistromic Reprogramming of the Diurnal Glucocorticoid Hormone Response by High-Fat Diet. Molecular Cell. 2019 Nov;76(4):531.

Seitzman BA, Gratton C, Laumann TO, Gordon EM, Adeyemo B, Dworetsky A, Kraus BT, Gilmore AW, Berg JJ, Ortega M, Nguyen A, Greene DJ, McDermott KB, Nelson SM, Lessov-Schlaggar CN, Schlaggar BL, Dosenbach NUF, Petersen SE. Trait-like variants in human functional brain networks.Proceedings of the National Academy of Sciences of the United States of America. 2019 Nov 5;116(45):22851-22861.

Sullivan DP, Dalal PJ, Jaulin F, Sacks DB, Kreitzer G, Muller WA. Endothelial IQGAP1 regulates leukocyte transmigration by directing the LBRC to the site of diapedesis. Journal of Experimental Medicine. 2019 Nov;216(11):2582-2601.

Visvanathan K, Fabian CJ, Bantug E, Brewster AM, Davidson NE, DeCensi A, Floyd JD, Garber JE, Hofstatter EW, Khan SA, Katapodi MC, Pruthi S, Raab R, Runowicz CD, Somerfield MR. Use of Endocrine Therapy for Breast Cancer Risk Reduction: ASCO Clinical Practice Guideline Update. Journal of Clinical Oncology. 2019 Nov 20;37(33):3152-3165.

Yu XG, Xie ZQ, Yu Y, Lee J, Vazquez-Guardado A, Luan HW, Ruben J, Ning X, Akhtar A, Li DF, Ji BW, Liu YM, Sun RJ, Cao JY, Huo QZ, Zhong YS, Lee C, Kim S, Gutruf P, Zhang CX, Xue YG, Guo QL, Chempakasseril A, Tian PL, Lu W, Jeong J, Yu Y, Cornman J, Tan C, Kirn B, Lee K, Feng X, Huang YG, Rogers JA. Skin-integrated wireless haptic interfaces for virtual and augmented reality. Nature. 2019 Nov;575(7783):473.

Zhang P, Miska J, Lee-Chang C, Rashidi A, Panek WK, An S, Zannikou M, Lopez-Rosas A, Han Y, Xiao T, Pituch KC, Kanojia D, Balyasnikova IV, Lesniak MS. Therapeutic targeting of tumor-associated myeloid cells synergizes with radiation therapy for glioblastoma. Proceedings of the National Academy of Sciences of the United States of America. 2019 Nov 19;116(47):23714-23723.

Burbulla LF, Jeon S, Zheng JB, Song PP, Silverman RB, Krainc D. A modulator of wild-type glucocerebrosidase improves pathogenic phenotypes in dopaminergic neuronal models of Parkinson's disease. Science Translational Medicine. 2019 Oct;11(514):11.

Clark DW, Okada Y, Moore KHS, et al. (including Cornelis M). Associations of autozygosity with a broad range of human phenotypes. Nat Communications. 2019 Oct 31;10(1):4957.

Dix DB, Fernandez CV, Chi YY, Mullen EA, Geller JI, Gratias EJ, Khanna G, Kalapurakal JA, Perlman EJ, Seibel NL, Ehrlich PF, Malogolowkin M, Anderson J, Gastier-Foster J, Shamberger RC, Kim Y, Grundy PE, Dome JS. Augmentation of Therapy for Combined Loss of Heterozygosity 1p and 16q in Favorable Histology Wilms Tumor: A Children's Oncology Group AREN0532 and AREN0533 Study Report.Journal of Clinical Oncology. 2019 Oct 20;37(30):2769-2777.

Giuliano M, Schettini F, Rognoni C, Milani M, Jerusalem G, Bachelot T, De Laurentiis M, Thomas G, De Placido P, Arpino G, De Placido S, Cristofanilli M, Giordano A, Puglisi F, Pistilli B, Prat A, Del Mastro L, Venturini S, Generali D. Endocrine treatment versus chemotherapy in postmenopausal women with hormone receptor-positive, HER2-negative, metastatic breast cancer: a systematic review and network meta-analysis. Lancet Oncology. 2019 Oct;20(10):1360-1369.

Henrichs J, Verfaille V, Jellema P, Viester L, Pajkrt E, Wilschut J, van der Horst HE, Franx A, de Jonge A, van Baar AL, Bais JMJ, Bonsel GJ, Bosmans JE, van Dillen J, van Duijnhoven NTL, Grobman WA, Groen H, Hukkelhoven C, Klomp T, Kok M, de Kroon ML, Kruijt M, Kwee A, Ledda S, Lafeber HN, van Lith JMM, Mol B, Molewijk B, Nieuwenhuijze M, Oei G, Oudejans C, Paarlberg KM, Papageorghiou AT, Reddy UM, De Reu P, Rijnders M, de Roon-Immerzeel A, Scheele C, Scherjon SA, Snijders R, Spaanderman ME, Teunissen PW, Torij HW, Vrijkotte TG, Westerneng M, Zeeman KC, Zhang JJ, Grp IS. Effectiveness of routine third trimester ultrasonography to reduce adverse perinatal outcomes in low risk pregnancy (the IRIS study): nationwide, pragmatic, multicentre, stepped wedge cluster randomised trial. BMJ-British Medical Journal. 2019 Oct;367:13.

Hu YY, Ellis RJ, Hewitt DB, Yang AD, Cheung EO, Moskowitz JT, Potts JR, 3rd, Buyske J, Hoyt DB, Nasca TJ, Bilimoria KY. Discrimination, Abuse, Harassment, and Burnout in Surgical Residency Training. New England Journal of Medicine. 2019 Oct 31;381(18):1741-1752.

Kaufmann T, van der Meer D, Doan NT, Schwarz E, Lund MJ, Agartz I, Alnaes D, Barch DM, Baur-Streubel R, Bertolino A, Bettella F, Beyer MK, Boen E, Borgwardt S, Brandt CL, Buitelaar J, Celius EG, Cervenka S, Conzelmann A, Cordova-Palomera A, Dale AM, de Quervain DJF, Carlo P, Djurovic S, Dorum ES, Eisenacher S, Elvsashagen T, Espeseth T, Fatouros-Bergman H, Flyckt L, Franke B, Frei O, Haatveit B, Haberg AK, Harbo HF, Hartman CA, Heslenfeld D, Hoekstra PJ, Hogestol EA, Jernigan TL, Jonassen R, Jonsson EG, Kirsch P, Kloszewska I, Kolskar KK, Landro NI, Hellard S, Lesch KP, Lovestone S, Lundervold A, Lundervold AJ, Maglanoc LA, Malt UF, Mecocci P, Melle I, Meyer-Lindenberg A, Moberget T, Norbom LB, Nordvik JE, Nyberg L, Oosterlaan J, Papalino M, Papassotiropoulos A, Pauli P, Pergola G, Persson K, Richard G, Rokicki J, Sanders AM, Selbaek G, Shadrin AA, Smeland OB, Soininen H, Sowa P, Steen VM, Tsolaki M, Ulrichsen KM, Vellas B, Wang L, Westman E, Ziegler GC, Zink M, Andreassen OA, Westlye LT. Common brain disorders are associated with heritable patterns of apparent aging of the brain. Nature Neuroscience. 2019 Oct;22(10):1617-1623.

Kim J, Hu C, Moufawad El Achkar C, Black LE, Douville J, Larson A, Pendergast MK, Goldkind SF, Lee EA, Kuniholm A, Soucy A, Vaze J, Belur NR, Fredriksen K, Stojkovska I, Tsytsykova A, Armant M, DiDonato RL, Choi J, Cornelissen L, Pereira LM, Augustine EF, Genetti CA, Dies K, Barton B, Williams L, Goodlett BD, Riley BL, Pasternak A, Berry ER, Pflock KA, Chu S, Reed C, Tyndall K, Agrawal PB, Beggs AH, Grant PE, Urion DK, Snyder RO, Waisbren SE, Poduri A, Park PJ, Patterson A, Biffi A, Mazzulli JR, Bodamer O, Berde CB, Yu TW. Patient-Customized Oligonucleotide Therapy for a Rare Genetic Disease.New England Journal of Medicine. 2019 Oct 24;381(17):1644-1652.

Manski CF, Tambur AR, Gmeiner M. Predicting kidney transplant outcomes with partial knowledge of HLA mismatch.Proceedings of the National Academy of Sciences of the United States of America. 2019 Oct 8;116(41):20339-20345.

Nam KW, Park SS, Dos Reis R, Dravid VP, Kim H, Mirkin CA, Stoddart JF. Conductive 2D metal-organic framework for high-performance cathodes in aqueous rechargeable zinc batteries. Nat Communications. 2019 Oct 30;10(1):4948.

Nassif ME, Windsor SL, Tang F, Khariton Y, Husain M, Inzucchi SE, Mc-Guire DK, Pitt B, Scirica BM, Austin B, Drazner MH, Fong MW, Givertz MM, Gordon RA, Jermyn R, Katz SD, Lamba S, Lanfear DE, LaRue SJ, Lindenfeld J, Malone M, Margulies K, Mentz RJ, Mutharasan RK, Pursley M, Umpierrez G, Kosiborod M. Dapagliflozin Effects on Biomarkers, Symptoms, and Functional Status in Patients With Heart Failure With Reduced Ejection Fraction: The DEFINE-HF Trial. Circulation. 2019 Oct 29;140(18):1463-1476.

Phan HP, Zhong Y, Nguyen TK, Park Y, Dinh T, Song E, Vadivelu RK, Masud MK, Li J, Shiddiky MJA, Dao D, Yamauchi Y, Rogers JA, Nguyen NT. Long-Lived, Transferred Crystalline Silicon Carbide Nanomembranes for Implantable Flexible Electronics. ACS Nano. 2019 Oct 22;13(10):11572-11581.

Ramachandran K, Senagolage MD, Sommars MA, Futtner CR, Omura Y, Allred AL, Barish GD. Dynamic enhancers control skeletal muscle identity and reprogramming. PLoS Biology. 2019 Oct;17(10):e3000467. 

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Choi J, Troyanovsky RB, Indra I, Mitchell BJ, Troyanovsky SM.Scribble, Erbin, and Lano redundantly regulate epithelial polarity and apical adhesion complex.Journal of Cell Biology. 2019 Jul;218(7):2277-2293.

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Ng LCT, Vien TN, Yarov-Yarovoy V, DeCaen PG.Opening TRPP2 (PKD2L1) requires the transfer of gating charges.Proceedings of the National Academy of Sciences of the United States of America. 2019 Jul;116(31):15540-15549.

Owens DK, Davidson KW, Krist AH, Barry MJ, Cabana M, Caughey AB, Doubeni CA, Epling JW, Jr., Kemper AR, Kubik M, Landefeld CS, Mangione CM, Pbert L, Silverstein M, Simon MA, Tseng CW, Wong JB. Screening for Hepatitis B Virus Infection in Pregnant Women: US Preventive Services Task Force Reaffirmation Recommendation Statement. JAMA-Journal of the American Medical Association. 2019 Jul 23;322(4):349-354.

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Sin-Chan P, Mumal I, Suwal T, et al. (including Schnitzer TJ). A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor. Cancer Cell. 2019 Jul;36(1):51.

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Ji Z, He LZ, Regev A, Struhl K. Inflammatory regulatory network mediated by the joint action of NF-kB, STAT3, and AP-1 factors is involved in many human cancers. Proceedings of the National Academy of Sciences of the United States of America. 2019;116(19):9453-9462.

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Perak AM, Ning HY, Kit BK, de Ferranti SD, Van Horn LV, Wilkins JT, Lloyd-Jones DM. Trends in Levels of Lipids and Apolipoprotein B in US Youths Aged 6 to 19 Years, 1999-2016. JAMA-Journal of the American Medical Association. 2019;321(19):1895-1905.

Reynolds AW, Mata-Miguez J, Miro-Herrans A, Briggs-Cloud M, Sylestine A, Barajas-Olmos F, Garcia-Ortiz H, Rzhetskaya M, Orozco L, Raff JA, Hayes MG, Bolnick DA. Comparing signals of natural selection between three Indigenous North American populations. Proceedings of the National Academy of Sciences of the United States of America. 2019;116(19):9312-9317.

Wang SY, Qin L, Yamankurt G, Skakuj K, Huang ZY, Chen PC, Dominguez D, Lee A, Zhang B, Mirkin CA. Rational vaccinology with spherical nucleic acids. Proceedings of the National Academy of Sciences of the United States of America. 2019;116(21):10473-10481.

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