Northwestern University Feinberg School of Medicine
Research

High-Impact-Factor Research 2017

Bao X, Siprashvili Z, Zarnegar BJ, Shenoy RM, Rios EJ, Nady N, Qu K, Mah A, Webster DE, Rubin AJ, Wozniak GG, Tao S, Wysocka J, Khavari PA. CSNK1a1 Regulates PRMT1 to Maintain the Progenitor State in Self-Renewing Somatic Tissue. Developmental Cell. 2017 Oct 23;43(2):227-239.e225.

Barefield DY, Puckelwartz MJ, Kim EY, Wilsbacher LD, Vo AH, Waters EA, Earley JU, Hadhazy M, Dellefave-Castillo L, Pesce LL, McNally EM. Experimental Modeling Supports a Role for MyBP-HL as a Novel Myofilament Component in Arrhythmia and Dilated Cardiomyopathy. Circulation. 2017 Oct;136(16):1477-1491.

Escobedo N, Oliver G. The Lymphatic Vasculature: Its Role in Adipose Metabolism and Obesity. Cell Metabolism. 2017 Oct;26(4):598-609.

Gadd S, Huff V, Walz AL, Ooms A, Armstrong AE, Gerhard DS, Smith MA, Auvil JMG, Meerzaman D, Chen QR, Hsu CH, Yan CH, Nguyen C, Hu Y, Hermida LC, Davidsen T, Gesuwan P, Ma Y, Zong ZS, Mungall AJ, Moore RA, Marra MA, Dome JS, Mullighan CG, Ma J, Wheeler DA, Hampton OA, Ross N, Gastier-Foster JM, Arold ST, Perlman EJ. A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor. Nature Genetics. 2017 Oct;49(10):1487.

Kim J, Park DY, Bae H, Park DY, Kim D, Lee CK, Song S, Chung TY, Lim DH, Kubota Y, Hong YK, He YL, Augustin HG, Oliver G, Koh GY. Impaired angiopoietin/Tie2 signaling compromises Schlemm's canal integrity and induces glaucoma. Journal of Clinical Investigation. 2017 Oct;127(10):3877-3896.

Mehta MM, Weinberg SE, Chandel NS. Mitochondrial control of immunity: beyond ATP. Nature Reviews Immunology. 2017 Oct;17(10):608-620.

Morgan MAJ, Rickels RA, Collings CK, He X, Cao K, Herz HM, Cozzolino KA, Abshiru NA, Marshall SA, Rendleman EJ, Sze CC, Piunti A, Kelleher NL, Savas JN, Shilatifard A. A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation. Genes & Development. 2017 Oct 01;31(19):2003-2014.

Motl RW, Sandroff BM, Kwakkel G, Dalgas U, Feinstein A, Heesen C, Feys P, Thompson AJ. Exercise in patients with multiple sclerosis. Lancet Neurology. 2017 Oct;16(10):848-856.

Pavel ME, Singh S, Strosberg JR, Bubuteishvili-Pacaud L, Degtyarev E, Neary MP, Carnaghi C, Tomasek J, Wolin E, Raderer M, Lahner H, Valle JW, Pommier R, Van Cutsem E, Tesselaar MET, Delle Fave G, Buzzoni R, Hunger M, Eriksson J, Cella D, Ricci JF, Fazio N, Kulke MH, Yao JC. Health-related quality of life for everolimus versus placebo in patients with advanced, non-functional, well-differentiated gastrointestinal or lung neuroendocrine tumours (RADIANT-4): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Oncology. 2017 Oct;18(10):1411-1422.

Reddy A, Zhang J, Davis NS, Moffitt AB, Love CL, Waldrop A, Leppa S, Pasanen A, Meriranta L, Karjalainen-Lindsberg ML, Norgaard P, Pedersen M, Gang AO, Hogdall E, Heavican TB, Lone W, Iqbal J, Qin Q, Li GJ, Kim SY, Healy J, Richards KL, Fedoriw Y, Bernal-Mizrachi L, Koff JL, Staton AD, Flowers CR, Paltiel O, Goldschmidt N, Calaminici M, Clear A, Gribben J, Nguyen E, Czader MB, Ondrejka SL, Collie A, Hsi ED, Tse E, Au-Yeung RKH, Kwong YL, Srivastava G, Choi WWL, Evens AM, Pilichowska M, Sengar M, Reddy N, Li SY, Chadburn A, Gordon LI, Jaffe ES, Levy S, Rempel R, Tzeng T, Happ LE, Dave T, Rajagopalan D, Datta J, Dunson DB, Dave SS. Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma. Cell. 2017 Oct;171(2):481.

Sathiyamoorthy K, Jiang JS, Mohl BS, Chen J, Zhou ZH, Longnecker R, Jardetzky TS. Inhibition of EBV-mediated membrane fusion by anti-gHgL antibodies. Proceedings of the National Academy of Sciences of the United States of America. 2017 Oct;114(41):E8703-E8710.

Wolchok JD, Chiarion-Sileni V, Gonzalez R, Rutkowski P, Grob JJ, Cowey CL, Lao CD, Wagstaff J, Schadendorf D, Ferrucci PF, Smylie M, Dummer R, Hill A, Hogg D, Haanen J, Carlino MS, Bechter O, Maio M, Marquez-Rodas I, Guidoboni M, McArthur G, Lebbe C, Ascierto PA, Long GV, Cebon J, Sosman J, Postow MA, Callahan MK, Walker D, Rollin L, Bhore R, Hodi FS, Larkin J. Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma. New England Journal of Medicine. 2017 Oct 05;377(14):1345-1356.

Wong JJW, Young TA, Zhang JY, Liu SH, Leser GP, Komives EA, Lamb RA, Zhou ZH, Salafsky J, Jardetzky TS. Monomeric ephrinB2 binding induces allosteric changes in Nipah virus G that precede its full activation. Nature Communications. 2017 Oct;8:11.

Yoo SH, Kojima S, Shimomura K, Koike N, Buhr ED, Furukawa T, Ko CH, Gloston G, Ayoub C, Nohara K, Reyes BA, Tsuchiya Y, Yoo OJ, Yagita K, Lee C, Chen Z, Yamazaki S, Green CB, Takahashi JS. Period2 3 '-UTR and microRNA-24 regulate circadian rhythms by repressing PERIOD2 protein accumulation. Proceedings of the National Academy of Sciences of the United States of America. 2017 Oct;114(42):E8855-E8864.

Zha L, Jiang YD, Henke MT, Wilson MR, Wang JX, Kelleher NL, Balskus EP. Colibactin assembly line enzymes use S-adenosylmethionine to build a cyclopropane ring. Nature Chemical Biology. 2017 Oct;13(10):1063.

 

Ahmad FS, Chan C, Rosenman MB, Post WS, Fort DG, Greenland P, Liu KJ, Kho AN, Allen NB. Validity of Cardiovascular Data From Electronic Sources: The Multi-Ethnic Study of Atherosclerosis and HealthLNK. Circulation. 2017 Sep 26;136(13):1207-1216.

Burbulla LF, Song PP, Mazzulli JR, Zampese E, Wong YC, Jeon S, Santos DP, Blanz J, Obermaier CD, Strojny C, Savas JN, Kiskinis E, Zhuang XX, Kruger R, Surmeier DJ, Krainc D.Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson's disease. Science. 2017 Sep;357(6357):1255.

Chen FX, Xie P, Collings CK, Cao KX, Aoi YK, Marshall SA, Rendleman EJ, Ugarenko M, Ozark PA, Zhang A, Shiekhattar R, Smith ER, Zhang MQ, Shilatifard A. PAF1 regulation of promoter-proximal pause release via enhancer activation. Science. 2017 Sep;357(6357):1294-1298.

Chlebowski RT, Aragaki AK, Anderson GL, Thomson CA, Manson JE, Simon MS, Howard BV, Rohan TE, Snetselar L, Lane D, Barrington W, Vitolins MZ, Womack C, Qi L, Hou L, Thomas F, Prentice RL. Low-Fat Dietary Pattern and Breast Cancer Mortality in the Women's Health Initiative Randomized Controlled Trial. Journal of Clinical Oncology. 2017 Sep 01;35(25):2919-2926.

Chu HY, McIver EL, Kovaleski RF, Atherton JF, Bevan MD. Loss of Hyperdirect Pathway Cortico-Subthalamic Inputs Following Degeneration of Midbrain Dopamine Neurons. Neuron. 2017 Sep;95(6):1306.

Forrest MP, Zhang HW, Moy W, McGowan H, Leites C, Dionisio LE, Xu ZH, Shi JX, Sanders AR, Greenleaf WJ, Cowan CA, Pang ZP, Gejman PV, Penzes P, Duan JB. Open Chromatin Profiling in hiPSC-Derived Neurons Prioritizes Functional Noncoding Psychiatric Risk Variants and Highlights Neurodevelopmental Loci. Cell Stem Cell. 2017 Sep;21(3):305.

Fullman N, Barber RM, Abajobir AA (including Yano Y, et al.). Measuring progress and projecting attainment on the basis of past trends of the health-related Sustainable Development Goals in 188 countries: an analysis from the Global Burden of Disease Study 2016. Lancet. 2017 Sep;390(10100):1423-1459.

Giuliano AE, Ballman KV, McCall L, Beitsch PD, Brennan MB, Kelemen PR, Ollila DW, Hansen NM, Whitworth PW, Blumencranz PW, Leitch AM, Saha S, Hunt KK, Morrow M. Effect of Axillary Dissection vs No Axillary Dissection on 10-Year Overall Survival Among Women With Invasive Breast Cancer and Sentinel Node Metastasis The ACOSOG Z0011 (Alliance) Randomized Clinical Trial. JAMA. 2017 Sep;318(10):918-926.

Gooding HC, Ning H, Gillman MW, Shay C, Allen N, Goff DC, Lloyd-Jones D, Chiuve S. Application of a Lifestyle-Based Tool to Estimate Premature Cardiovascular Disease Events in Young Adults The Coronary Artery Risk Development in Young Adults (CARDIA) Study. JAMA Internal Medicine. 2017 Sep;177(9):1354-1360.

Grossman DC, Curry SJ, Owens DK, Barry MJ, Davidson KW, Doubeni CA, Epling JW, Kemper AR, Krist AH, Kurth AE, Landefeld CS, Mangione CM, Phipps MG, Silverstein M, Simon MA, Tseng CW, Force USPST. Vision Screening in Children Aged 6 Months to 5 Years US Preventive Services Task Force Recommendation Statement. JAMA. 2017 Sep;318(9):836-844.

Hay SI, Abajobir AA, Abate KH, (including Yano Y, et al.) Collaborators GBDDH. Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017 Sep;390(10100):1260-1344.

Hegde SM, Claggett B, Shah AM, Lewis EF, Anand I, Shah SJ, Sweitzer NK, Fang JC, Pitt B, Pfeffer MA, Solomon SD. Physical Activity and Prognosis in the TOPCAT Trial (Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist). Circulation. 2017 Sep;136(11):982-992.

McNally EM, Wyatt EJ.Mutation-Based Therapy for Duchenne Muscular Dystrophy Antisense Treatment Arrives in the Clinic. Circulation. 2017 Sep;136(11):979-981.

Naghavi M, Abajobir AA, Abbafati C, (including Yano Y, et al.) Collaborato GBDCD. Global, regional, and national age-sex specific mortality for 264 causes of death, 1980-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017 Sep;390(10100):1151-1210.

Sasaguri H, Nilsson P, Hashimoto S, Nagata K, Saito T, De Strooper B, Hardy J, Vassar R, Winblad B, Saido TC. APP mouse models for Alzheimer's disease preclinical studies. EMBO Journal. 2017 Sep;36(17):2473-2487.

Saygin C, Wiechert A, Rao VS, Alluri R, Connor E, Thiagarajan PS, Hale JS, Li Y, Chumakova A, Jarrar A, Parker Y, Lindner DJ, Nagaraj AB, Kim JJ, DiFeo A, Abdul-Karim FW, Michener C, Rose PG, DeBernardo R, Mahdi H, McCrae KR, Lin F, Lathia JD, Reizes O. CD55 regulates self-renewal and cisplatin resistance in endometrioid tumors. Journal of Experimental Medicine. 2017 Sep;214(9):2715-2732.

Sims R, van der Lee SJ, Naj AC, (including Bigio EH, et al.).Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. 2017 Sep;49(9):1373.

Sleep E, Cosgrove BD, McClendon MT, Preslar AT, Chen CH, Sangji MH, Perez CMR, Haynes RD, Meade TJ, Blau HM, Stupp SI. Injectable biomimetic liquid crystalline scaffolds enhance muscle stem cell transplantation. Proceedings of the National Academy of Sciences of the United States of America. 2017 Sep;114(38):E7919-E7928.

Sze CC, Cao K, Collings CK, Marshall SA, Rendleman EJ, Ozark PA, Chen FX, Morgan MA, Wang L, Shilatifard A.Histone H3K4 methylation-dependent and -independent functions of Set1A/COMPASS in embryonic stem cell self-renewal and differentiation. Genes & Development. 2017 Sep 01;31(17):1732-1737.

Vos T, Abajobir AA, Abbafati C, (including Yano Y, et al.). Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017 Sep;390(10100):1211-1259.

Wang HD, Abajobir AA, Abate KH, (including Yano Y, et al.). Collaborators GBDM. Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017 Sep;390(10100):1084-1150.

Wheeler E, Leong A, Liu CT, (including Rasmussen-Torvik L, et al.). Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. PLoS Medicine. 2017 Sep;14(9):e1002383.

 

Bangasser DA, Dong H, Carroll J, Plona Z, Ding H, Rodriguez L, McKennan C, Csernansky JG, Seeholzer SH, Valentino RJ. Corticotropin-releasing factor overexpression gives rise to sex differences in Alzheimer's disease-related signaling. Molecular Psychiatry. 2017 Aug;22(8):1126-1133.

Clevenger KD, Bok JW, Ye R, Miley GP, Verdan MH, Velk T, Chen C, Yang K, Robey MT, Gao P, Lamprecht M, Thomas PM, Islam MN, Palmer JM, Wu CC, Keller NP, Kelleher NL. A scalable platform to identify fungal secondary metabolites and their gene clusters. Nature Chemical Biology. 2017 Aug;13(8):895-901.

Curtis DS, Fuller-Rowell TE, El-Sheikh M, Carnethon MR, Ryff CD. Habitual sleep as a contributor to racial differences in cardiometabolic risk. Proceedings of the National Academy of Sciences of the United States of America. 2017 Aug;114(33):8889-8894.

Delaney MK, Malikov V, Chai QQ, Zhao GY, Naghavi MH.Distinct functions of diaphanous-related formins regulate HIV-1 uncoating and transport. Proceedings of the National Academy of Sciences of the United States of America. 2017 Aug;114(33):E6932-E6941.

Eagen KP, Aiden EL, Kornberg RD. Polycomb-mediated chromatin loops revealed by a subkilobase-resolution chromatin interaction map. Proceedings of the National Academy of Sciences of the United States of America. 2017 Aug;114(33):8764-8769.

Elegheert J, Cvetkovska V, Clayton AJ, Heroven C, Vennekens KM, Smukowski SN, Regan MC, Jia WY, Smith AC, Furukawa H, Savas JN, de Wit J, Begbie J, Craig AM, Aricescu AR. Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins. Neuron. 2017 Aug;95(4):896.

Flevaris P, Khan SS, Eren M, Schuldt AJT, Shah SJ, Lee DC, Gupta S, Shapiro AD, Burridge PW, Ghosh AK, Vaughan DE. Plasminogen Activator Inhibitor Type I Controls Cardiomyocyte Transforming Growth Factor-beta and Cardiac Fibrosis. Circulation. 2017 Aug 15;136(7):664-679.

Khanna A, English SW, Wang XYS, Ham K, Tumlin J, Szerlip H, Busse LW, Altaweel L, Albertson TE, Mackey C, McCurdy MT, Boldt DW, Chock S, Young PJ, Krell K, Wunderink RG, Ostermann M, Murugan R, Gong MN, Panwar R, Hastbacka J, Favory R, Venkatesh B, Thompson BT, Bellomo R, Jensen J, Kroll S, Chawla LS, Tidmarsh GF, Deane AM, Investigators A-. Angiotensin II for the Treatment of Vasodilatory Shock. New England Journal of Medicine. 2017 Aug;377(5):419-430.

Kwa M, Welty LJ, Xu S.Adverse Events Reported to the US Food and Drug Administration for Cosmetics and Personal Care Products. JAMA Internal Medicine. 2017 Aug;177(8):1202-1204.

Lee SS, Fyrner T, Chen F, Alvarez Z, Sleep E, Chun DS, Weiner JA, Cook RW, Freshman RD, Schallmo MS, Katchko KM, Schneider AD, Smith JT, Yun CW, Singh G, Hashmi SZ, McClendon MT, Yu ZL, Stock SR, Hsu WK, Hsu EL, Stupp SI. Sulfated glycopeptide nanostructures for multipotent protein activation. Nature Nanotechnology. 2017 Aug;12(8):821.

Limaye AP, Stapleton RD, Peng L, Gunn SR, Kimball LE, Hyzy R, Exline MC, Files DC, Morris PE, Frankel SK, Mikkelsen ME, Hite D, Enfield KB, Steingrub J, O'Brien J, Parsons PE, Cuschieri J, Wunderink RG, Hotchkin DL, Chen YQ, Rubenfeld GD, Boeckh M. Effect of Ganciclovir on IL-6 Levels Among Cytomegalovirus-Seropositive Adults With Critical Illness: A Randomized Clinical Trial. JAMA. 2017 Aug 22;318(8):731-740.

Liu Y, Reynolds LM, Ding J, Hou L, Lohman K, Young T, Cui W, Huang Z, Grenier C, Wan M, Stunnenberg HG, Siscovick D, Hou L, Psaty BM, Rich SS, Rotter JI, Kaufman JD, Burke GL, Murphy S, Jacobs DR, Jr., Post W, Hoeschele I, Bell DA, Herrington D, Parks JS, Tracy RP, McCall CE, Stein JH. Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis. Nature Communication. 2017 Aug 30;8(1):393.

Mackenzie IR, Nicholson AM, Sarkar M, Messing J, Purice MD, Pottier C, Annu K, Baker M, Perkerson RB, Kurti A, Matchett BJ, Mittag T, Temirov J, Hsiung GYR, Krieger C, Murray ME, Kato M, Fryer JD, Petrucelli L, Zinman L, Weintraub S, Mesulam M, Keith J, Zivkovic SA, Hirsch-Reinshagen V, Roos RP, Zuchner S, Graff-Radford NR, Petersen RC, Caselli RJ, Wszolek ZK, Finger E, Lippa C, Lacomis D, Stewart H, Dickson DW, Kim HJ, Rogaeva E, Bigio E, Boylan KB, Taylor JP, Rademakers R. TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics. Neuron. 2017 Aug;95(4):808.

Mamede JI, Cianci GC, Anderson MR, Hope TJ.Early cytoplasmic uncoating is associated with infectivity of HIV-1. Proceedings of the National Academy of Sciences of the United States of America. 2017 Aug;114(34):E7169-E7178.

Misharin AV, Morales-Nebreda L, Reyfman PA, Cuda CM, Walter JM, McQuattie-Pimentel AC, Chen CI, Anekalla KR, Joshi N, Williams KJN, Abdala-Valencia H, Yacoub TJ, Chi M, Chiu S, Gonzalez-Gonzalez FJ, Gates K, Lam AP, Nicholson TT, Homan PJ, Soberanes S, Dominguez S, Morgan VK, Saber R, Shaffer A, Hinchcliff M, Marshall SA, Bharat A, Berdnikovs S, Bhorade SM, Bartom ET, Morimoto RI, Balch WE, Sznajder JI, Chandel NS, Mutlu GM, Jain M, Gottardi CJ, Singer BD, Ridge KM, Bagheri N, Shilatifard A, Budinger GRS, Perlman H.Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span. Journal of Experimental Medicine. 2017 Aug 07;214(8):2387-2404.

Perl AE, Altman JK, Cortes J, Smith C, Litzow M, Baer MR, Claxton D, Erba HP, Gill S, Goldberg S, Jurcic JG, Larson RA, Liu CF, Ritchie E, Schiller G, Spira AI, Strickland SA, Tibes R, Ustun C, Wang ES, Stuart R, Rollig C, Neubauer A, Martinelli G, Bahceci E, Levis M. Selective inhibition of FLT3 by gilteritinib in relapsed or refractory acute myeloid leukaemia: a multicentre, first-in-human, open-label, phase 1-2 study. Lancet Oncology. 2017 Aug;18(8):1061-1075.

Pollack CV, Reilly PA, van Ryn J, Eikelboom JW, Glund S, Bernstein RA, Dubiel R, Huisman MV, Hylek EM, Kam CW, Kamphuisen PW, Kreuzer J, Levy JH, Royle G, Sellke FW, Stangier J, Steiner T, Verhamme P, Wang BS, Young L, Weitz JI. Idarucizumab for Dabigatran Reversal - Full Cohort Analysis. New England Journal of Medicine. 2017 Aug;377(5):431-441.

Shen WK, Sheldon RS, Benditt DG, Cohen MI, Forman DE, Goldberger ZD, Grubb BP, Hamdan MH, Krahn AD, Link MS, Olshansky B, Raj SR, Sandhu RK, Sorajja D, Sun BC, Yancy CW. 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope: Executive Summary A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. Circulation. 2017 Aug;136(5):E25.

Shen WK, Sheldon RS, Benditt DG, Cohen MI, Forman DE, Goldberger ZD, Grubb BP, Hamdan MH, Krahn AD, Link MS, Olshansky B, Raj SR, Sandhu RK, Sorajja D, Sun BC, Yancy CW. 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. Circulation. 2017 Aug;136(5):E60.

Shih YCT, Xu Y, Liu L, Smieliauskas F. Rising Prices of Targeted Oral Anticancer Medications and Associated Financial Burden on Medicare Beneficiaries. Journal of Clinical Oncology. 2017 Aug;35(22):2482.

Tap WD, Papai Z, Van Tine BA, Attia S, Ganjoo KN, Jones RL, Schuetze S, Reed D, Chawla SP, Riedel RF, Krarup-Hansen A, Toulmonde M, Ray-Coquard I, Hohenberger P, Grignani G, Cranmer LD, Okuno S, Agulnik M, Read W, Ryan CW, Alcindor T, del Muro XFG, Budd GT, Tawbi H, Pearce T, Kroll S, Reinke DK, Schoffski P. Doxorubicin plus evofosfamide versus doxorubicin alone in locally advanced, unresectable or metastatic soft-tissue sarcoma (TH CR-406/SARC021): an international, multicentre, open-label, randomised phase 3 trial. Lancet Oncology. 2017 Aug;18(8):1089-1103.

Wang W, Zhang H, Liu S, Kim CK, Xu Y, Hurley LA, Nishikawa R, Nagane M, Hu B, Stegh AH, Cheng SY, Cheng C.Internalized CD44s splice isoform attenuates EGFR degradation by targeting Rab7A. Proceedings of the National Academy of Sciences of the United States of America. 2017 Aug 01;114(31):8366-8371.

Xie Z, Gordiichuk P, Lin QY, Meckes B, Chen PC, Sun L, Du JS, Zhu J, Liu Y, Dravid VP, Mirkin CA. Solution-Phase Photochemical Nanopatterning Enabled by High-Refractive-Index Beam Pen Arrays. ACS Nano. 2017 Aug 22;11(8):8231-8241.

Yancy CW, Jessup M, Bozkurt B, Butler J, Casey DE, Colvin MM, Drazner MH, Filippatos GS, Fonarow GC, Givertz MM, Hollenberg SM, Lindenfeld J, Masoudi FA, McBride PE, Peterson PN, Stevenson LW, Westlake C. 2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America. Circulation. 2017 Aug;136(6):E137.

Abiria SA, Krapivinsky G, Sah R, Santa-Cruz AG, Chaudhuri D, Zhang J, Adstamongkonkul P, DeCaen PG, Clapham DE. TRPM7 senses oxidative stress to release Zn2+ from unique intracellular vesicles. Proceedings of the National Academy of Sciences of the United States of America. 2017 Jul 25;114(30):E6079-e6088.

Afshin A, Forouzanfar MH, et al. (including Yano, Y). Health Effects of Overweight and Obesity in 195 Countries over 25 Years. New England Journal of Medicine. 2017 Jul;377(1):13-27.

Barber RM, Fullman N, et al. (including Yano, Y). Healthcare Access and Quality Index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the Global Burden of Disease Study 2015. Lancet. 2017 Jul;390(10091):231-266.

Bergenstal RM, Gal RL, Connor CG, Gubitosi-Klug R, Kruger D, Olson BA, Willi SM, Aleppo G, Weinstock RS, Wood J, Rickels M, DiMeglio LA, Bethin KE, Marcovina S, Tassopoulos A, Lee S, Massaro E, Bzdick S, Ichihara B, Markmann E, McGuigan P, Woerner S, Ecker M, Beck RW, St TDERD. Racial Differences in the Relationship of Glucose Concentrations and Hemoglobin A(1c) Levels. Annals of Internal Medicine. 2017 Jul;167(2):95-102.

Chang JK, Fang H, Bower CA, Song EM, Yu XG, Rogers JA. Materials and processing approaches for foundry-compatible transient electronics. Proceedings of the National Academy of Sciences of the United States of America. 2017 Jul;114(28):E5522-E5529.

Freeman R, Stephanopoulos N, Alvarez Z, Lewis JA, Sur S, Serrano CM, Boekhoven J, Lee SS, Stupp SI. Instructing cells with programmable peptide DNA hybrids. Nature Communications. 2017 Jul;8:11.

Henssen AG, Koche R, Zhuang JL, Jiang E, Reed C, Eisenberg A, Still E, MacArthur IC, Rodriguez-Fos E, Gonzalez S, Puiggros M, Blackford AN, Mason CE, de Stanchina E, Gonen M, Emde AK, Shah M, Arora K, Reeves C, Socci ND, Perlman E, Antonescu CR, Roberts CWM, Steen H, Mullen E, Jackson SP, Torrents D, Weng ZP, Armstrong SA, Kentsis A. PGBD5 promotes site-specific oncogenic mutations in human tumors. Nature Genetics. 2017 Jul;49(7):1005.

Kapur NK, Esposito ML, Bader Y, Morine KJ, Kiernan MS, Pham DT, Burkhoff D. Mechanical Circulatory Support Devices for Acute Right Ventricular Failure. Circulation. 2017 Jul;136(3):314-326.

Kershaw KN, Robinson WR, Gordon-Larsen P, Hicken MT, Goff DC, Carnethon MR, Kiefe CI, Sidney S, Roux AVD. Association of Changes in Neighborhood-Level Racial Residential Segregation With Changes in Blood Pressure Among Black Adults The CARDIA Study. JAMA Internal Medicine. 2017 Jul;177(7):996-1002.

Landsburg DJ, Falkiewicz MK, Maly J, Blum KA, Howlett C, Feldman T, Mato AR, Hill BT, Li SY, Medeiros LJ, Torka P, Hernandez-Ilizaliturri F, Reddy NM, Singavi A, Fenske TS, Chavez JC, Kaplan JB, Behdad A, Petrich AM, Bast MA, Vose JM, Olszewski AJ, Costa C, Lansigan F, Gerson JN, Barta SK, Calzada O, Cohen JB, Lue JK, Amengual JE, Rivera X, Persky DO, Peace DJ, Nathan S, Cassaday RD. Outcomes of Patients With Double-Hit Lymphoma Who Achieve First Complete Remission. Journal of Clinical Oncology. 2017 Jul;35(20):2260.

Langefeld CD, Ainsworth HC, et al. (including Ramsey-Goldman, R). Transancestral mapping and genetic load in systemic lupus erythematosus. Nature Communications. 2017 Jul;8:18.

McDade TW, Ryan C, Jones MJ, MacIsaac JL, Morin AM, Meyer JM, Borja JB, Miller GE, Kobor MS, Kuzawa CW. Social and physical environments early in development predict DNA methylation of inflammatory genes in young adulthood. Proceedings of the National Academy of Sciences of the United States of America. 2017 Jul 18;114(29):7611-7616.

Miller TE, Liau BB, Wallace LC, Morton AR, Xie Q, Dixit D, Factor DC, Kim LJY, Morrow JJ, Wu QL, Mack SC, Hubert CG, Gillespie SM, Flavahan WA, Hoffmann T, Thummalapalli R, Hemann MT, Paddison PJ, Horbinski CM, Zuber J, Scacheri PC, Bernstein BE, Tesar PJ, Rich JN. Transcription elongation factors represent in vivo cancer dependencies in glioblastoma. Nature. 2017 Jul;547(7663):355.

Park SQ, Kahnt T, Dogan A, Strang S, Fehr E, Tobler PN. A neural link between generosity and happiness. Nature Communications. 2017 Jul;8:10.

Sacks FM, Lichtenstein AH, Wu JHY, Appel LJ, Creager MA, Kris-Etherton PM, Miller M, Rimm EB, Rudel LL, Robinson JG, Stone NJ, Van Horn LV, American Heart A. Dietary Fats and Cardiovascular Disease A Presidential Advisory From the American Heart Association. Circulation. 2017 Jul;136(3):E1.

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