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Northwestern University Feinberg School of Medicine
ReVAMP

Cleaver Group

Ondine Cleaver headshot in lab

Ondine Cleaver, PhD

UT Southwestern Medical Center
Dallas, Texas, USA
ondine.cleaver@UTSouthwestern.edu

We study vascular cell fate and how progenitor cells assemble into blood vessels. Our group is particularly interested in intracellular signaling events that drive cytoskeletal or adhesion changes within progenitor cells, allowing them to assemble into functional tissues. We are interested in how cues in the microenvironment drive vascular assembly or growth, and how blood vessels in turn communicate paracrine, non-nutritional signals to stem cell niches. We also study how blood vessels maintain their integrity and how this can go awry due to genetic or hemodynamic defects.

VISIT THE CLEAVER LAB SITE

Group Members

Stephen Spurgin
Stephen Spurgin
stephen.spurgin@utsouthwestern.edu
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Stephen Spurgin is a pediatric cardiology fellow at UT Southwestern/Children’s Health, where he is a member of the Physician Scientist Training Program in Pediatrics (PSTP2). He is currently a Pediatric Scientist Development Program (PSDP) fellow working in Dr. Ondine Cleaver’s lab, where his research focuses on the development of pulmonary arteriovenous malformations in the setting of congenital heart disease. He is a native of Dallas, Texas, and graduated from Stanford University prior to completing medical school and pediatrics residency at UT Southwestern.

Tuli Pramanik
Tuli Pramanik
tuli.pramanik@utsouthwestern.edu
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I did my Bachelors from St. Xavier’s College, Kolkata, India. I also have a Masters from Tata Institute of Fundamental Research in Mumbai, India, where I studied forebrain development. I am currently a third-year graduate student in Ondine Cleaver’s lab at UT Southwestern Medical Center. I am interested in identifying new candidates in vascular development and their implications in Vascular Malformations.