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Northwestern University Feinberg School of Medicine
Center for Translational Pain Research
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Browse our calendar to find out about upcoming events related to our work.



CANCELLED - CANCELLED: Cellular Pathology in the Prefrontal Cortex in Neuropathic Pain - Theodore Price, PhD

Chicago - 12:00 PM - 1:00 PM

Theodore Price, PhD
Eugene McDermott Professor
Director, Systems Neuroscience Program, School of Behavioral and Brain Sciences
Director of the Center for Advanced Pain Studies
University of Texas (UT) at Dallas

Join us remotely via Panopto.

It is now well-known that neuropathic pain causes dysfunction in the cortex in both humans and rodents. We have developed new behavioral methods and cellular profiling techniques to better understand how behavioral pathology is linked to molecular changes in the prefrontal cortex. I will discuss our work on how attentional set-shifting is disrupted in mice with neuropathic pain and how this can be rescued by different types of therapeutics. I will also discuss how neuropathic pain targets a subset of pyramidal neurons in the infralimbic cortex causing shrinkage of their axon initial segments, a change that can also be rescued by drug treatment. Finally, I will discuss our unpublished work using translating ribosome affinity purification to molecularly profile these neurons in neuropathic pain. Those experiments reveal similarities with transcriptomic differences that occur in chronic stress and reveal potential cortical targets for pain therapeutics.

Theodore (Ted) Price, PhD, is the Eugene McDermott Professor and Director of the Systems Neuroscience Program in the School of Behavioral and Brain Sciences at University of Texas (UT) at Dallas. He is also the Director of the Center for Advanced Pain Studies at UT Dallas. He did his PhD work with Chris Flores and Ken Hargreaves at UT Health San Antonio and a postdoctoral fellowship at McGill University with Fernando Cervero. He started his independent laboratory in 2007 at University of Arizona School of Medicine and moved to UT Dallas in 2014. His lab is interested in molecular mechanisms driving the transition to chronic pain with a focus on drug development for chronic pain disease modification and on peripheral and central mechanisms of neuronal plasticity in response to injury. He has won numerous awards including the John C Liebeskind Early Career Scholar Award from the American Pain Society and The Patrick D. Wall Young Investigator Award from the International Association for the Study of Pain. Ted serves on editorial boards for leading pain and neuroscience journals such as Pain and Journal of Neuroscience, and is a standing member of the Somatosensory and Pain Study Section for NIH.




CANCELLED - CANCELLED: Center for Translational Pain Research Seminar - Frank Porreca, PhD

Chicago - 12:00 PM - 1:00 PM

Frank Porreca, PhD
Associate Department Head, Department of Pharmacology
Professor of Anesthesiology, Cancer Biology - Graduate Interdisciplinary Program (GIDP), Pharmacology, and
Neuroscience - GIDP
University of Arizona College of Medicine - Tucson




Center for Translational Pain Research Seminar - Antonello Bonci, MD

Chicago - 12:00 PM - 1:00 PM

Antonello Bonci, MD
Scientific Director, National Institute on Drug Abuse (NIDA)
Adjunct Professor of Psychiatry and Neuroscience
The Johns Hopkins School of Medicine
Adjunct Professor of Psychiatry
University of Maryland School of Medicine
Adjunct Professor of Neuroscience
Georgetown University School of Medicine


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