Exploring host-pathogen interactions and immunological mechanisms.

Upcoming Seminars and Events

News and Publications

Recent Publications

Activity and inhibition of the SARS-CoV-2 Omicron nsp13 R392C variant using RNA duplex unwinding assays.

Inniss NL, Rzhetskaya M, Ling-Hu T, Lorenzo-Redondo R, Bachta KE, Satchell KJF, Hultquist JF.

SLAS Discov. 2024 Feb 1:S2472-5552(24)00007-8. doi: 10.1016/j.slasd.2024.01.006. Online ahead of print.

Biochemical and Structural Analysis of the Bacterial Enzyme Succinyl-Diaminopimelate Desuccinylase (DapE) from Acinetobacter baumannii.

Kelley EH, Minasov G, Konczak K, Shuvalova L, Brunzelle JS, Shukla S, Beulke M, Thabthimthong T, Olsen KW, Inniss NL, Satchell KJF, Becker DP.

ACS Omega. 2024 Jan 8;9(3):3905-3915. doi: 10.1021/acsomega.3c08231. eCollection 2024 Jan 23.

Epitranscriptional m6A modification of rRNA negatively impacts translation and host colonization in Staphylococcus aureus.

Shields KE, Ranava D, Tan Y, Zhang D, Yap MF.

PLoS Pathog. 2024 Jan 22;20(1):e1011968. doi: 10.1371/journal.ppat.1011968. eCollection 2024 Jan.

The immune system and metabolic products in epilepsy and glioma-associated epilepsy: emerging therapeutic directions.

Tripathi S, Nathan CL, Tate MC, Horbinski CM, Templer JW, Rosenow JM, Sita TL, James CD, Deneen B, Miller SD, Heimberger AB.

JCI Insight. 2024 Jan 9;9(1):e174753. doi: 10.1172/jci.insight.174753.

Development and implementation of a Type I-C CRISPR-based programmable repression system for Neisseria gonorrhoeae.

Geslewitz WE, Cardenas A, Zhou X, Zhang Y, Criss AK, Seifert HS.

mBio. 2024 Feb 14;15(2):e0302523. doi: 10.1128/mbio.03025-23. Epub 2023 Dec 21.

What We Do

Welcome to the Department of Microbiology-Immunology, a basic science department at Northwestern University Feinberg School of Medicine. Our dedicated faculty are experts in the areas of bacteriology, virology and immunology and guide the training of our students and postdoctoral fellows. Learn more below.


We examine pathogen-host cell interactions and dissect the molecular mechanisms involved in regulation of the immune response. 


Our faculty members also teach undergraduate, graduate and medical students at Northwestern University and Feinberg.

Center for Structural Biology of Infectious Diseases

The Center for Structural Biology of Infectious Diseases (CSBID) is a consortium of laboratories using state-of-the-art, high-throughput structural biology methods to determine the three-dimensional structures of protein targets from pathogens in the NIAID Category A-C priority lists and organisms causing emerging and re-emerging infectious diseases.


Basic Science Administration

Our department is supported by the Basic Science Administration group. The team provides assistance related to research and financial administration, professional affairs, facilities and communications.


Research Resources

We offer a wide range of resources, mentorship opportunities and training to help our residents and fellows excel as physician-scientists. Explore all of the resources and hear from housestaff who are making research a major part of their career development plans.

VISIT THE Starzl Academy Site