Exploring host-pathogen interactions and immunological mechanisms.

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News and Publications

Recent Publications

The mTORC1-SLC4A7 axis stimulates bicarbonate import to enhance de novo nucleotide synthesis.

Ali ES, Lipońska A, O'Hara BP, Amici DR, Torno MD, Gao P, Asara JM, Yap MF, Mendillo ML, Ben-Sahra I.

Mol Cell. 2022 Jun 24:S1097-2765(22)00544-5. doi: 10.1016/j.molcel.2022.06.008. Online ahead of print.

Tolerogenic Immune-Modifying Nanoparticles Encapsulating Multiple Recombinant Pancreatic β Cell Proteins Prevent Onset and Progression of Type 1 Diabetes in Nonobese Diabetic Mice.

Podojil JR, Genardi S, Chiang MY, Kakade S, Neef T, Murthy T, Boyne MT 2nd, Elhofy A, Miller SD.

J Immunol. 2022 Jun 20:ji2200208. doi: 10.4049/jimmunol.2200208. Online ahead of print.

The Neisseria gonorrhoeae type IV pilus promotes resistance to hydrogen peroxide- and LL-37-mediated killing by modulating the availability of intracellular, labile iron.

Hu LI, Stohl EA, Seifert HS.

PLoS Pathog. 2022 Jun 17;18(6):e1010561. doi: 10.1371/journal.ppat.1010561. eCollection 2022 Jun.

Latent Membrane Proteins from EBV Differentially Target Cellular Pathways to Accelerate MYC-induced Lymphomagenesis.

Ikeda M, Hayes CK, Schaller SJ, Longnecker R.

Blood Adv. 2022 May 23:bloodadvances.2022007695. doi: 10.1182/bloodadvances.2022007695. Online ahead of print.

Herpes Simplex Virus (HSV)-2 Variation Contributes to Neurovirulence During Neonatal Infection.

Hayes CK, Villota CK, McEnany FB, Cerón S, Awasthi S, Szpara ML, Friedman HM, Leib DA, Longnecker R, Weitzman MD, Akhtar LN.

J Infect Dis. 2022 Apr 22:jiac151. doi: 10.1093/infdis/jiac151. Online ahead of print.

What We Do

Welcome to the Department of Microbiology-Immunology, a basic science department at Northwestern University Feinberg School of Medicine. Our dedicated faculty are experts in the areas of bacteriology, virology and immunology and guide the training of our students and postdoctoral fellows. Learn more below.

Research

We examine pathogen-host cell interactions and dissect the molecular mechanisms involved in regulation of the immune response. 
EXPLORE OUR AREAS OF FOCUS

Education

Our faculty members also teach undergraduate, graduate and medical students at Northwestern University and Feinberg.
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Center for Structural Genomics of Infectious Diseases

CSGID is a consortium of laboratories using state-of-the-art, high-throughput structural biology methods to determine the three-dimensional structures of protein targets from pathogens in the NIAID Category A-C priority lists and organisms causing emerging and re-emerging infectious diseases.

VISIT THE CSGID SITE

Basic Science Administration

Our department is supported by the Basic Science Administration group. The team provides assistance related to research and financial administration, professional affairs, facilities and communications.

VISIT BASIC SCIENCE ADMINISTRATION SITE

Research Resources

We offer a wide range of resources, mentorship opportunities and training to help our residents and fellows excel as physician-scientists. Explore all of the resources and hear from housestaff who are making research a major part of their career development plans.

VISIT THE Starzl Academy Site