Exploring host-pathogen interactions and immunological mechanisms.
Upcoming Seminars and Events
No upcoming events.
News and Publications
Recent Publications
Structural studies on ribosomes of differentially macrolide-resistant Staphylococcus aureus strains.
Rivalta A, Fedorenko A, Le Scornet A, Thompson S, Halfon Y, Breiner Goldstein E, Çavdaroglu S, Melenitzky T, Hiregange DG, Zimmerman E, Bashan A, Yap MF, Yonath A.
Life Sci Alliance. 2025 Jun 9;8(8):e202503325. doi: 10.26508/lsa.202503325. Print 2025 Aug.
CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13.
Herasymenko O, Silva M, Abu-Saleh AAA, Ahmad A, Alvarado-Huayhuaz J, Arce OEA, Armstrong RJ, Arrowsmith C, Bachta KE, Beck H, Berta D, Bieniek MK, Blay V, Bolotokova A, Bourne PE, Breznik M, Brown PJ, Campbell ADG, Carosati E, Chau I, Cole DJ, Cree B, Dehaen W, Denzinger K, Dos Santos Machado K, Dunn I, Durai P, Edfeldt K, Edwards A, Fayne D, Felfoldi D, Friston K, Ghiabi P, Gibson E, Günther J, Gunnarsson A, Hillisch A, Houston DR, Jensen JH, Harding RJ, Harris KS, Hoffer L, Hogner A, Horton JT, Houliston S, Hultquist JF, Hutchinson A, Irwin JJ, Jukič M, Kandwal S, Karlova A, Katis VL, Kich RP, Kireev D, Koes D, Inniss NL, Lessel U, Liu S, Loppnau P, Lu W, Martino S, McGibbon M, Meiler J, Mettu A, Money-Kyrle S, Moretti R, Moroz YS, Muvva C, Newman JA, Obendorf L, Paige B, Pandit A, Park K, Perveen S, Pirie R, Poda G, Protopopov M, Pütter V, Ricci F, Roper NJ, Rosta E, Rzhetskaya M, Sabnis Y, Satchell KJF, Schmitt Kremer F, Scott T, Seitova A, Steinmann C, Talagayev V, Tarkhanova OO, Tatum NJ, Treleaven D, Velasque Werhli A, Walters WP, Wang X, Wells J, Wells G, Westermaier Y, Wolber G, Wortmann L, Zhang J, Zhao Z, Zheng S, Schapira M.
J Chem Inf Model. 2025 Jul 14;65(13):6884-6898. doi: 10.1021/acs.jcim.5c00535. Epub 2025 Jun 20.
Adams CO, Campbell JA, Zhang B, Cleaver L, Bier SB, Mayoral J, White RC, Garnett JA, Cianciotto NP.
mBio. 2025 Jul 9;16(7):e0139325. doi: 10.1128/mbio.01393-25. Epub 2025 Jun 20.
Nas MY, Gabell J, Inniss N, Minasov G, Shuvalova L, Satchell KJF, Cianciotto NP.
Acta Crystallogr F Struct Biol Commun. 2025 Jul 1;81(Pt 7):287-296. doi: 10.1107/S2053230X2500490X. Epub 2025 Jun 4.
LAG3 regulates antibody responses in a murine model of kidney transplantation.
Nicosia M, Fan R, Lee J, All G, Gorbacheva V, Valenzuela JI, Yamamoto Y, Beavers A, Dvorina N, Baldwin WM 3rd, Chuluyan E, Araki M, Gaudette BT, Fairchild RL, Min B, Valujskikh A.
J Clin Invest. 2025 May 13;135(13):e172988. doi: 10.1172/JCI172988. eCollection 2025 Jul 1.
What We Do
Welcome to the Department of Microbiology-Immunology, a basic science department at Northwestern University Feinberg School of Medicine. Our dedicated faculty are experts in the areas of bacteriology, virology and immunology and guide the training of our students and postdoctoral fellows. Learn more below.
Research
We examine pathogen-host cell interactions and dissect the molecular mechanisms involved in regulation of the immune response.
Education
Our faculty members also teach undergraduate, graduate and medical students at Northwestern University and Feinberg.
Center for Structural Biology of Infectious Diseases
The Center for Structural Biology of Infectious Diseases (CSBID) is a consortium of laboratories using state-of-the-art, high-throughput structural biology methods to determine the three-dimensional structures of protein targets from pathogens in the NIAID Category A-C priority lists and organisms causing emerging and re-emerging infectious diseases.
Basic Science Administration
Our department is supported by the Basic Science Administration group. The team provides assistance related to research and financial administration, professional affairs, facilities and communications.
Research Resources
We offer a wide range of resources, mentorship opportunities and training to help our residents and fellows excel as physician-scientists. Explore all of the resources and hear from housestaff who are making research a major part of their career development plans.
Health Equity
Our vision is to make Northwestern, our communities, all communities, our lives and the world a better place — with everyone having the chance and responsibility for reaching their own pinnacle of health.
