Exploring host-pathogen interactions and immunological mechanisms.
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News and Publications
Recent Publications
Carmona-Salido H, Salvador-Clavell R, Jäckel C, Schulze I, Satchell KJF, Hammerl JA, Amaro C.
Emerg Microbes Infect. 2026 Dec;15(1):2601370. doi: 10.1080/22221751.2025.2601370. Epub 2025 Dec 23.
Zuckerman SL, White M, Rigney GH, Jo J, Bailes JE, Bonfield CM, Cantu RC, Chan PCH, Cordover AM, Coric D, Feuer H, Gardocki RJ, Hecht AC, Hsu WK, Joseph JR, Lehman RA Jr, Levi AD, Liew SM, Louie PK, Ludwig SC, Maroon J, Miele VJ, Mullin J, Nemani VM, Phillips FM, Qureshi S, Riew KD, Rogers MA, Sasso RC, Smith GA, Turner JD, Vaccaro AR, Watkins RG 4th, Theodore N, Okonkwo DO, Sills AK, Davis GA.
Spine (Phila Pa 1976). 2026 Jan 1;51(1):16-24. doi: 10.1097/BRS.0000000000005464. Epub 2025 Aug 21.
Zyxin restricts viral fusion and entry across multiple virus families.
Fan Q, Quan J, Smith GA, Longnecker R.
J Virol. 2025 Dec 23;99(12):e0165925. doi: 10.1128/jvi.01659-25. Epub 2025 Nov 24.
IL-27 promotes Treg cell expression of CD122 and fitness at homeostasis.
Lanzar ZR, Aldridge DL, Cruz-Morales E, Howard CA, Conway IO, Zhong Z, Eberhard JN, Pereira JA, Phan AT, Ring AM, Parker M, Kanellopoulou C, Min B, Kedl RM, Christian DA, Hunter CA.
Proc Natl Acad Sci U S A. 2025 Dec 16;122(50):e2519141122. doi: 10.1073/pnas.2519141122. Epub 2025 Dec 9.
IL-27 limits HSPC differentiation during infection and protects from stem cell exhaustion.
Aldridge DL, Lanzar Z, Phan AT, Christian DA, Pardy RD, Min B, Kedl R, Hunter CA.
Elife. 2025 Dec 15;14:RP105876. doi: 10.7554/eLife.105876.
What We Do
Welcome to the Department of Microbiology-Immunology, a basic science department at Northwestern University Feinberg School of Medicine. Our dedicated faculty are experts in the areas of bacteriology, virology and immunology and guide the training of our students and postdoctoral fellows. Learn more below.
Research
We examine pathogen-host cell interactions and dissect the molecular mechanisms involved in regulation of the immune response.
Education
Our faculty members also teach undergraduate, graduate and medical students at Northwestern University and Feinberg.
Center for Structural Biology of Infectious Diseases
The Center for Structural Biology of Infectious Diseases (CSBID) is a consortium of laboratories using state-of-the-art, high-throughput structural biology methods to determine the three-dimensional structures of protein targets from pathogens in the NIAID Category A-C priority lists and organisms causing emerging and re-emerging infectious diseases.
Basic Science Administration
Our department is supported by the Basic Science Administration group. The team provides assistance related to research and financial administration, professional affairs, facilities and communications.
Research Resources
We offer a wide range of resources, mentorship opportunities and training to help our residents and fellows excel as physician-scientists. Explore all of the resources and hear from housestaff who are making research a major part of their career development plans.
Health Equity
Our vision is to make Northwestern, our communities, all communities, our lives and the world a better place — with everyone having the chance and responsibility for reaching their own pinnacle of health.
