Exploring host-pathogen interactions and immunological mechanisms.

Upcoming Seminars and Events

News and Publications

Recent Publications

YTHDF2 Is Downregulated in Response to Host Shutoff Induced by DNA Virus Infection and Regulates Interferon-Stimulated Gene Expression.

Hesser CR, Walsh D.

J Virol. 2023 Mar 14:e0175822. doi: 10.1128/jvi.01758-22. Online ahead of print.

Pre-existing immunity modulates responses to mRNA boosters.

Dangi T, Sanchez S, Lew MH, Awakoaiye B, Visvabharathy L, Richner JM, Koralnik IJ, Penaloza-MacMaster P.

Cell Rep. 2023 Feb 15;42(3):112167. doi: 10.1016/j.celrep.2023.112167. Online ahead of print.

CRISPR screens identify novel regulators of cFLIP dependency and ligand-independent, TRAIL-R1-mediated cell death.

Kuehnle N, Osborne SM, Liang Z, Manzano M, Gottwein E.

Cell Death Differ. 2023 Feb 18. doi: 10.1038/s41418-023-01133-0. Online ahead of print.

Cell type specific IL-27p28 (IL-30) deletion in mice uncovers an unexpected regulatory function of IL-30 in autoimmune inflammation.

Kim D, Kim S, Kang MS, Yin Z, Min B.

Sci Rep. 2023 Feb 1;13(1):1812. doi: 10.1038/s41598-023-27413-w.

Respiratory viruses: New frontiers-a Keystone Symposia report.

Cable J, Sun J, Cheon IS, Vaughan AE, Castro IA, Stein SR, López CB, Gostic KM, Openshaw PJM, Ellebedy AH, Wack A, Hutchinson E, Thomas MM, Langlois RA, Lingwood D, Baker SF, Folkins M, Foxman EF, Ward AB, Schwemmle M, Russell AB, Chiu C, Ganti K, Subbarao K, Sheahan TP, Penaloza-MacMaster P, Eddens T.

Ann N Y Acad Sci. 2023 Feb 1. doi: 10.1111/nyas.14958. Online ahead of print.

What We Do

Welcome to the Department of Microbiology-Immunology, a basic science department at Northwestern University Feinberg School of Medicine. Our dedicated faculty are experts in the areas of bacteriology, virology and immunology and guide the training of our students and postdoctoral fellows. Learn more below.


We examine pathogen-host cell interactions and dissect the molecular mechanisms involved in regulation of the immune response. 


Our faculty members also teach undergraduate, graduate and medical students at Northwestern University and Feinberg.

Center for Structural Genomics of Infectious Diseases

CSGID is a consortium of laboratories using state-of-the-art, high-throughput structural biology methods to determine the three-dimensional structures of protein targets from pathogens in the NIAID Category A-C priority lists and organisms causing emerging and re-emerging infectious diseases.


Basic Science Administration

Our department is supported by the Basic Science Administration group. The team provides assistance related to research and financial administration, professional affairs, facilities and communications.


Research Resources

We offer a wide range of resources, mentorship opportunities and training to help our residents and fellows excel as physician-scientists. Explore all of the resources and hear from housestaff who are making research a major part of their career development plans.

VISIT THE Starzl Academy Site