Exploring host-pathogen interactions and immunological mechanisms.
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News and Publications
Recent Publications
Ligand-receptor interactions induce and mediate regulatory functions of BATF3+ B cells.
Yan H, Wang R, Viswanadhapalli S, Cervantes C, He F, Wu S, Khosh A, Luo W, Wang J, Fernandez MJ, Pratap UP, Khan M, Hinton K, Vankamamidi SE, Perez D, Rivera CE, Gupta HB, Zhang F, Ye Z, Chen Y, Li XD, Sareddy GR, Zan H, Li Y, Wang E, Bunnik EM, Zhong G, Hunter CA, Kedl RM, Yin Z, Min B, Ebrahimi D, Zheng S, Curiel TJ, Xiang Y, Vadlamudi RK, Casali P, Xu Z.
Sci Adv. 2025 Oct 10;11(41):eadx9917. doi: 10.1126/sciadv.adx9917. Epub 2025 Oct 8.
Juric I, Fink EE, Qiu H, Desprez PE, Ravi A, Holton M, Makarov V, Almassi N, Min B, Getz G, Chan TA, Alban T, Ting AH, Lee BH.
NPJ Precis Oncol. 2025 Sep 26;9(1):318. doi: 10.1038/s41698-025-01093-3.
Stanton V, Himes B, Mejia-Santana A, Eppinger M, Romo J, Xing J, Zhulin IB, Cai H, Wang Y, Inniss Nl, Minasov G, Satchell KJF, Klose KE.
mBio. 2025 Sep 22:e0237925. doi: 10.1128/mbio.02379-25. Online ahead of print.
Cytotoxicity of activator expression in CRISPR-based transcriptional activation systems.
Liang Z, Maddineni A, Ortega JA, Magdongon CB, Jambardi S, Roy S, Tycko J, Patil A, Manzano M, Bartom ET, Gottwein E.
Nat Commun. 2025 Aug 29;16(1):8071. doi: 10.1038/s41467-025-63570-4.
Gu F, Naghavi MH.
Proc Natl Acad Sci U S A. 2025 Aug 26;122(34):e2503988122. doi: 10.1073/pnas.2503988122. Epub 2025 Aug 21.
What We Do
Welcome to the Department of Microbiology-Immunology, a basic science department at Northwestern University Feinberg School of Medicine. Our dedicated faculty are experts in the areas of bacteriology, virology and immunology and guide the training of our students and postdoctoral fellows. Learn more below.
Research
We examine pathogen-host cell interactions and dissect the molecular mechanisms involved in regulation of the immune response.
Education
Our faculty members also teach undergraduate, graduate and medical students at Northwestern University and Feinberg.
Center for Structural Biology of Infectious Diseases
The Center for Structural Biology of Infectious Diseases (CSBID) is a consortium of laboratories using state-of-the-art, high-throughput structural biology methods to determine the three-dimensional structures of protein targets from pathogens in the NIAID Category A-C priority lists and organisms causing emerging and re-emerging infectious diseases.
Basic Science Administration
Our department is supported by the Basic Science Administration group. The team provides assistance related to research and financial administration, professional affairs, facilities and communications.
Research Resources
We offer a wide range of resources, mentorship opportunities and training to help our residents and fellows excel as physician-scientists. Explore all of the resources and hear from housestaff who are making research a major part of their career development plans.
Health Equity
Our vision is to make Northwestern, our communities, all communities, our lives and the world a better place — with everyone having the chance and responsibility for reaching their own pinnacle of health.
