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Methodologic Core

Learn about FIRST-DailyLife's goals, services, and leadership that make up our methodologic core.

Goals

Our Methodologic Core's goals are to:

  • Enhance methodologic training environment.
  • Provide methodologic, consultative, and collaborative capabilities regarding:
    • Study design and data collection methods
    • Statistical science and analysis
    • Epidemiology
    • Behavioral science
    • Nutritional science
    • Implementation science/innovative study design
    • Economic evaluation/decision science
    • Genomics/bioinformatics
    • Clinical informatics
    • Data management
  • Provide access to research databases.

Services

Our Methodologic Core can provide input on aim development, study design, and data collection methods from a multidisciplinary group of scientist-methodologists. Learn more about our Methodologic Core's areas of expertise and services below.

  Statistical Science and Analysis

  • Statistical study design/sample size methodology.
  • Longitudinal data analysis.
  • Clinical trial design and analysis.
  • Secondary data analyses.
  • Hypothesis generating/exploratory analyses.
  • Microarray data analysis.

 Epidemiology

  • Observational and clinical trial study designs.
  • Use of patient reported and other outcomes in rheumatology.
  • Registry development.
  • Access to large clinical and national datasets.
  • Application of geographic information system tools.

 Implementation Research

  • “Real world” measurements, modeling and testing of community and service delivery/health system interventions.

 Behavioral and Nutritional Sciences

  • Modifiable chronic disease risk factor behavior intervention.
  • Behavioral theory/behavioral mechanism grounding for intervention development.
  • Modern research designs to optimize behavioral interventions.

 Economic Evaluation/Decision Science

  • Cost effectiveness analysis
  • Cost utility analysis
  • Cost analysis
  • Budget impact analysis
  • Design and analysis of “appropriateness” studies

 Functional Genomics

  • Design and Analysis of RNA-seq or other functional genomic experiments.
  • Meta-analysis of existing/published genomic data sets.
  • Integrated analysis of genomic data with other data types (such as genetic/GWAS, proteomic, or clinical).

 Clinical Informatics/Data Management

  • Data collection strategies.
  • Creation and maintenance of research data systems.
  • Extraction of data from the NM Electronic Data Warehouse, the integrated database of all clinical and research data from all patients receiving treatment through Northwestern healthcare affiliates.
  • Creation of databases amenable to geographic information systems analyses.

Request Help

FIRST-DailyLife can help you through an array of consultative services originating from three Cores.

Sign up to become a member and view some examples of areas in which we can help.

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