Northwestern University Feinberg School of Medicine

Department of Cell & Developmental Biology


The cytoskeleton is a key component of eukaryotic cells and is comprised of intermediate filaments, actin filaments and microtubules. Together with molecular motors and a large number of regulatory proteins, the cytoskeleton provides mechanical strength, regulates signal transduction and provides a means of moving organelles and materials within the cell. It also provides the mechanical force for cell motility, cytokinesis, axonal transport and many other basic cellular functions.

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