In order for cells, tissues and organs to survive and function in an integrated fashion, they must have a way of communicating. This can involve mechanical signaling and chemical signaling.
Through research, our faculty investigates:
- The proteins involved in regulating the interactions between epithelial cells and the extracellular matrix
- How the extracellular matrix is assembled and remodeled
- How cells in a tissue polarize relative to each other
- How organelles within a cell communicate with each other and coordinate their activities
- How mitochondrial and nuclear genetic systems coordinate with each other to meet the cells energy demands
Labs in this Research Area
Autophagy in metabolic regulation and pathogenesis of metabolic diseases
Our goal is to understand the integration of signaling and cytoskeletal dynamics on diverse developmental processes including centriole amplification, cell migration and cell polarity.
Looking to further define the molecular interactions and physiological functions of transcriptional activators and co-activators involved in the nuclear control of the respiratory apparatus