Read the latest news from Northwestern University Feinberg School of Medicine’s Department of Cell and Molecular Biology. The links below take you to articles and announcements about our faculty’s latest achievements, awards, and honors.
A protein involved in DNA replication was found to also play a role in microtubule binding during mitosis, an unexpected secondary function, according to a Northwestern Medicine study published in the Journal of Cell Biology.
These findings could inform more effective cancer treatments and help answer larger questions about molecular mechanisms, according to Dileep Varma, PhD, assistant professor of Cell and Molecular Biologyand senior author of the study.
- 11.08.2018Northwestern Medicine scientists have demonstrated that a protein called HRD1 is a novel regulator of liver metabolism and could serve as a potential therapeutic target for obesity, type 2 diabetes and related conditions.
An experimental genetic inhibitor that could stave off Alzheimer’s disease has unintended consequences, but may represent a target for future drug development, according to a recent study.
Faculty, family and friends gathered at a symposium to honor Robert Goldman, PhD, chair of Cell and Molecular Biology, and his distinguished scientific career.
A new study finds that excessive carbon dioxide in a patient’s bloodstream can lead to a restricted airway, calling into question current clinical practices for patients with chronic obstructive pulmonary disease.
A protein facilitating DNA replication during cell cycle also binds microtubules, findings that could inform more effective cancer treatments, according to a recent study published in the Journal of Cell Biology.
A motor protein called kinesin drives a unique mechanism that ensures correct placement of important proteins and mRNA during development of egg cells.
- H Foundation Pilot Project Award Recipients Announced: High Throughput Screening and Medicinal Chemistry07.31.2018
Treating mice with isradipine, a calcium channel blocker, prevented formation of toxic compounds that can cause Parkinson’s disease symptoms, according to a recent Northwestern Medicine study.
Enhancing autophagy, the system that recycles old or dysfunctional cells, could have therapeutic effects in a variety of aging-related diseases, according to a pair of Northwestern Medicine studies.
A simple scrape or sore might not cause alarm for most people. But for diabetic patients, an untreated scratch can turn into an open wound that could potentially lead to a limb amputation or even death.
A Northwestern University team has developed a new device, called a regenerative bandage, that quickly heals these painful, hard-to-treat sores without using drugs. During head-to-head tests published in Proceedings of the National Academy of Sciences, Northwestern’s bandage healed diabetic wounds 33 percent faster than one of the most popular bandages currently on the market.
New compound inhibits the spread of human prostate, breast and pancreatic cancer in mice.
- 05.16.2018Researchers have identified a compound that blocks the spread of pancreatic and other cancers in various animal models. When cancer spreads from one part of the body to another in a process called metastasis, it can eventually grow beyond the reach of effective therapies. Now, there is a new plan of attack against this deadly process, thanks to scientists at the National Institutes of Health, Northwestern University and their collaborative research partners.
A study, published in Proceedings of the National Academy of Sciences, provides new insights into the organization of a key protein called cadherin within structures called adherens junctions, which help cells stick together.
The roots of a progressive degenerative disease begin much earlier than previously thought, according to a recent Northwestern Medicine study.
Northwestern Medicine scientists have identified a signaling protein that regulates cell organization, with implications for early development and certain diseases.
- Northwestern Research Magazine Winter 2018 - Books: "Now You See it: Breakthroughs that Reveal Our Tiny, Teeming Inner Life."03.13.2018
The previously unknown cause of anti-phosphatidylethanolamine (aPE) autoimmunity was discovered in a Northwestern Medicine study published in PNAS.
Thomas Hope, PhD, professor in Cell and Molecular Biology, Obstetrics and Gynecology and Biomedical Engineering discusses the Sustained Long-Acting Protection Against HIV (SLAP HIV) program, funded by the NIH’s National Institute of Allergy and Infectious Diseases (NIAID). The interdisciplinary project aims to invent, develop and test an implantable drug delivery system to protect high-risk individuals from HIV infection for up to a year at a time.
A team from Northwestern Medicine used the most powerful X-ray source in the Western Hemisphere to examine an 1,800-year old mummy, seeking answers to questions about bone competence of ancient humans.
Northwestern Medicine scientists identified a complex regulatory system that keeps cells functioning when their oxygen supply is cut off.
A study has shown that a recently-discovered type of RNA is specific to certain cell types, which may make it possible to use those RNA sequences as a marker in stem cell research.
Northwestern Medicine scientists have developed a novel method of tracking HIV infection, allowing the behavior of individual virions to be connected to infectivity.
Mitochondria have an important role in hematopoiesis, the body’s process for creating new blood cells, according to new Northwestern Medicine research.
A new study defined the architecture of nuclear lamins, the fibrous proteins in a cell’s nucleus, providing further insights into their role in cell structure.
In research published in Nature Medicine, Northwestern Medicine scientists have found a molecule that stops the growth of an aggressive pediatric brain tumor for which there is no current treatment.