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Northwestern University Feinberg School of Medicine
Cell & Developmental Biology

Publications

Peer-reviewed publications from our department's core faculty over the past three years listed in reverse chronological order.

2026

  • Suva, E.E., & Mitchell, B.J. (2026). Crashing by design: Utilizing DNA damage for MCC differentiation. Trends in cell biology, S0962-8924(26)00101-7. Advance online publication. https://doi.org/10.1016/j.tcb.2026.06.002

  • Schwartz, L., Pholraksa, P., & Goyal, Y. (2026). Spatial CRISPR screens map total RNA in tissue. Nature biotechnology, 10.1038/s41587-026-03126-z. Advance online publication. https://doi.org/10.1038/s41587-026-03126-z

  • Tan, C., Ren, Z., Kurup, S., Liu, X., Ge, Z.D., Suzuki, S., Jakka, P., Tang, C., Iruela-Arispe, M.L., & Kume, T. (2026). Lymphatic dysfunction and ZFP36 deficiency contribute to myxomatous valve degeneration in Marfan Syndrome mice. The Journal of clinical investigation, e195507. Advance online publication. https://doi.org/10.1172/JCI195507

  • Mayo, L.N., Duong, F., Mompeón, A., Jacobs, K. A., Iruela-Arispe, M.L., & Kutys, M.L. (2026). Scrib organizes cortical actomyosin clusters to maintain adherens junctions and angiogenic sprouting. The Journal of cell biology, 225(6), e202503146. https://doi.org/10.1083/jcb.202503146 

  • Wang, Y., Kulkarni, V. V., Pantaleón García, J., Ntita, M., Chavez Cavazos, M., Reese, T. C., Liu, Y., Vila Ellis, L., Tuvim, M. J., & Evans, S. E. (2026). Phosphorothioate Backbone Modification of Oligodeoxynucleotides Induces TLR9-Independent Lung Epithelial Antimicrobial Responses. American journal of respiratory cell and molecular biology,74(6), 755–767. https://doi.org/10.1093/ajrcmb/aanag011

  • Carias, A.M., Stroupe, C.C., Russo, T., & Hope, T.J. (2026). The Spatial Biology of HIV Transmission and Infection: Imaging the Female and Male Reproductive Tracts. American journal of reproductive immunology (New York, N.Y. : 1989), 95(6), e70261. https://doi.org/10.1111/aji.70261

  • Samaniego-Castruita, D., Han, I., Morgan, R.C., Carpenter, S., Williams, B., Chakraborty, A., Radhakrishnan, I., Ay, F., Myers, S.A., Rao, A., & Shukla, V. (2026). CTCF directly binds G-quadruplex structures to regulate genome topology and gene expression. Proceedings of the National Academy of Sciences of the United States of America, 123(22), e2509164123. https://doi.org/10.1073/pnas.2509164123

  • Sorond, F.A., Gorelick, P.B., Bae, H.J., Carmichael, S.T., Greenberg, S.M., Hinman, J.D., Iadecola, C., Iruela-Arispe, M.L., Leonard, A., Valdes, E., Waddy, S.P., & American Heart Association Stroke Council; Council on Cardiovascular Surgery and Anesthesia; and Council on Lifelong Congenital Heart Disease and Heart Health in the Young (2026). Vascular Contributions to Cognitive Impairment and Brain Health: Clinical Update and Mechanistic Considerations: A Scientific Statement From the American Heart Association. Stroke, 10.1161/STR.0000000000000524. Advance online publication. https://doi.org/10.1161/STR.0000000000000524

  • Spurgin, S. B., Thai, L., Wan, T. C., Chaney, C. P., Cowdin, M. A., Reddy, S. V., Hussain, T., Fares, M., Iruela-Arispe, M.L., Carroll, T., Spearman, A. D., & Cleaver, O. (2026). Pulsatile flow dynamics maintain pulmonary artery architecture. JCI insight, 11(9), e201797. https://doi.org/10.1172/jci.insight.201797

  • Penney, R., Buchanan, L. B., Rojas-Vargas, J., Lin, J., Khan, Y., Davidson, J., Wilson, C.A., Tai, V., Russo, T.A., Hope, T.J., Wilcox, H., Monari, B., Ravel, J., Al, K.F., Dave, S., Wang, P.Z.T., Burton, J.P., & Prodger, J.L. (2026). Pathological phimosis is associated with foreskin immune cell infiltration but not microbiota composition. mSphere, 11(4), e0072525. https://doi.org/10.1128/msphere.00725-25 

  • Iruela-Arispe, M.L. (2026). Who gets the calories? An endothelial checkpoint for fat expansion. The Journal of experimental medicine, 223(5), e20260240. https://doi.org/10.1084/jem.20260240

  • Penney, R., Buchanan, L. B., Rojas-Vargas, J., Lin, J., Khan, Y., Davidson, J., Wilson, C. A., Tai, V., Russo, T. A., Hope, T.J., Wilcox, H., Monari, B., Ravel, J., Al, K. F., Dave, S., Wang, P. Z. T., Burton, J. P., & Prodger, J. L. (2026). Pathological phimosis is associated with foreskin immune cell infiltration but not microbiota composition. mSphere, e0072525. Advance online publication. https://doi.org/10.1128/msphere.00725-25

  • Carey, C.M., Parvez, S., Brandt, Z.J., Bisgrove, B.W., Yates, C.J., Peterson, R.T., & Gagnon, J.A. (2026). MIC-Drop-seq: scalable single-cell phenotyping of mutant vertebrate embryos. Nature communications, 17(1), 4738. https://doi.org/10.1038/s41467-026-70989-w

  • Limdi, N., Beasley, T. M., Cortopassi, J., Davis, B., Bangash, H., Chen, J., Chisholm, R.L., Chung, W. K., Cimino, J. J., Connolly, J., Crosslin, D. R., Davis, K. W., DiVietro, A., Esplin, E. D., Freimuth, B., Gordon, A., Hakonarson, H., Hamed, M., He, M., Hoell, C., … Veenstra, D. L. (2026). The Electronic Medical Records and Genomics study: Design and analytic framework for assessing the impact of genome-informed risk assessments. American journal of human genetics, S0002-9297(26)00082-0. Advance online publication. https://doi.org/10.1016/j.ajhg.2026.02.018

  • Lawson, L. P., Prows, C. A., Cortopassi, J., Davis, K. W., Head, M., Martin, L. J., Perez, E. F., Sobowale, A., Abul-Husn, N. S., Bangash, H., Bland, H. T., Bonini, K. E., Chisholm, R.L., Chung, W. K., Cimino, J. J., Connolly, J. J., Crosslin, D. R., Freimuth, R. R., Goff, B., Gordon, A. S., … Kullo, I. (2026). Return of genome-informed risk-assessment results for common conditions to 23,840 adults and children: An eMERGE network study. American journal of human genetics, S0002-9297(26)00080-7. Advance online publication. https://doi.org/10.1016/j.ajhg.2026.02.016

  • Li, J., Ravindran, P. T., O'Farrell, A., Busch, G. T., Boe, R. H., Niu, Z., Woo, S., Dunagin, M. C., Jain, N., Goyal, Y., Sarma, K., Herlyn, M., & Raj, A. (2026). AP-1 mediates cellular adaptation and memory formation. Nature communications, 17(1), 4265. https://doi.org/10.1038/s41467-026-70862-w

  • Ranganathan, B., Adam, S.A., & Gelfand, V.I. (2026). Vimentin Intermediate Filaments: A Paradigm Shift From Static Structure to Dynamic Cytoplasmic Network. BioEssays : news and reviews in molecular, cellular and developmental biology, 48(3), e70125. https://doi.org/10.1002/bies.70125

  • Serlin, Y., Munn, C., Ferrante, E. A., Kamintsky, L., Cousineau-Krieger, C., FitzGibbon, E. J., …, Iruela-Arispe, M.L., …, Boehm, M. (2026). Retinal Vessel Dysfunction in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy. Neurology Open Access, 2(1), e000069. PMCID: PMC13262973.

  • Rebecca, V. W., Xiao, M., Kossenkov, A., Godok, T., Brown, G. S., Fingerman, D., Alicea, G. M., Wei, M., Ji, H., Portuallo, M., Bravo, J., Elad, V., Chen, Y., Toska, E., Fane, M. E., Couts, K. L., Villanueva, J., Nathanson, K., Arun, K. M., Warrier, G., … Goyal, Y., … Herlyn, M. (2026). Dasatinib resensitizes BRAF/MEK inhibitor efficacy in patient-derived xenografts from patients with progression on BRAF/MEK inhibitor treatment. iScience, 29(2), 114669. https://doi.org/10.1016/j.isci.2026.114669

  • Rodriguez, C., Jeong, H., Kim, J., Cordner, L. A., Cao, P., Sivagurunathan, S., Adam, S.A., Goldman, R. D., Wong, I. Y., & Guo, M. (2026). Expression of vimentin intermediate filaments in epithelial cells promotes cell migration and cell-matrix interaction in 3D. Biophysical journal, 125(4), 1185–1193. https://doi.org/10.1016/j.bpj.2026.01.022

  • Campbell, N. R., & Goyal, Y. (2026). Revisiting the molecular workhorse: plasmids in evolutionary conflict. Nature reviews. Genetics, 10.1038/s41576-026-00942-6. Advance online publication. https://doi.org/10.1038/s41576-026-00942-6

  • Moran, K. K., & Snead, W.T. (2026). Phases align at the membrane. Nature chemical biology, 10.1038/s41589-026-02144-x. Advance online publication. https://doi.org/10.1038/s41589-026-02144-x

  • Kim, J., Jeong, H., Falcó, C., Hruska, A. M., Martinson, W. D., Marzoratti, A., Araiza, M., Yang, H., Fonseca, V. C., Adam, S.A., Franck, C., Carrillo, J. A., Guo, M., & Wong, I. Y. (2026). Collective transitions from orbiting to matrix invasion in three-dimensional multicellular spheroids. Nature physics, 22(2), 275–286. https://doi.org/10.1038/s41567-025-03150-x

  • Chou, W. C., Lakonishok, M., Lu, W., Gelfand, V.I., & McCartney, B. M. (2026). Developmentally regulated actin-microtubule cross talk in Drosophila oogenesis. The Journal of cell biology, 225(3), e202411007. https://doi.org/10.1083/jcb.202411007

  • Gene Ontology Consortium [including Chisholm, R.L.] (2026). The Gene Ontology knowledgebase in 2026. Nucleic acids research, 54(D1), D1779–D1792. https://doi.org/10.1093/nar/gkaf1292

2025

  • Srivastava, S., Samaniego-Castruita, D., Srivastava, S., Khurana, S., Rehman, J., Shukla, V., Ben-Sahra, I., & Foltz, D. R. (2025). Rate-limiting enzymes in nucleotide metabolism synchronize nucleotide biosynthesis and chromatin formation. Molecular cell, 85(24), 4510–4525.e8. https://doi.org/10.1016/j.molcel.2025.11.009

  • Chaikof, E. L., Chen, J., Gillette, M. U., Boyer, L. A., Deans, T. L., Li, P., Hilton, I. B., Daniels, K., Goyal, Y., Mei, Y., Linghu, C., Loveless, T. B., Truong, D. M., Blatchley, M. R., Gu, M., Bashor, C. J., Yang, J. H., Raman, R., Reddy, A. B., Saha, K., … Galloway, K. E. (2025). Integrating synthetic biology to understand and engineer the heart, lung, blood, and sleep systems. Cell systems, 16(12), 101446. https://doi.org/10.1016/j.cels.2025.101446

  • Siniscalco, E. R., Meng, H., Gabernet, G., Pacheco, G. A., Saghaei, S., Ramirez, S. I., Hills, L. B., Faraji, F., Chen, S., Yin, X., Dien, C., Hoyt, L. R., Liu, E. G., Barrett, A., Briggs, N., Williams, A., Shukla, V., Crotty, S., Wesemann, D. R., Kleinstein, S. H., … Eisenbarth, S. C. (2025). Sequential class switching generates antigen-specific gut IgA from IgG1 B cells. Immunity, 58(12), 3075–3093.e6. https://doi.org/10.1016/j.immuni.2025.10.022

  • Manolio, T. A., Rupert, A., Narula, J., Bult, C. J., Chisholm, R.L., Ginsburg, G. S., Hooker, G. W., Jarvik, G. P., Mensah, G. A., Roden, D. M., Rowley, R., Taylor, C. O., Volpi, S., & Williams, M. S. (2025). Genomic medicine year in review: 2025. American journal of human genetics, 112(12), 2822–2825. https://doi.org/10.1016/j.ajhg.2025.11.001

  • Niu, Z., O'Farrell, A., Li, J., Reffsin, S., Jain, N., Dardani, I., Goyal, Y., & Raj, A. (2025). Piscis: A loss estimator of the F1 score enables accurate spot detection in fluorescence microscopy images via deep learning. Cell systems, 16(11), 101448. https://doi.org/10.1016/j.cels.2025.101448

  • Yi, Y., Fry, J., Yum, C., Wang, R., Wu, S., Narayan, S., Liu, Q., Zhang, X., Oo, H. Z., Xie, N., Li, Y., Gao, X., Yu, X., Hu, X., Li, Q., Keseroglu, K., Özbudak, E.M., Abdulkadir, S. A., Chen, K., Jin, J., … Cao, Q. (2025). EZH2 crosstalk with RNA methylation promotes prostate cancer progression through modulation of m6A autoregulation pathway. The Journal of clinical investigation, 136(2), e195840. https://doi.org/10.1172/JCI195840

  • Rosas-Lemus, M., Athe, S., Minasov, G., Pattie, J. A., Brunzelle, J. S., Chau, I., Li, F., Vedadi, M., Ma, H., Ramanathan, A., Becker, M. E., Hope, T.J., Abdelkarim, H., Grudzien, P., Gaponenko, V., Montgomery, J. E., Moellering, R. E., Rawal, V. H., & Satchell, K. J. F. (2025). S-adenosylhomocysteine analogs selectively suppress pan-coronavirus replication by inhibition of nsp14 methyltransferase. ACS medicinal chemistry letters, 10.1021/acsmedchemlett.5c00510. Advance online publication. https://doi.org/10.1021/acsmedchemlett.5c00510

  • Langat, R., McRaven, M. D., Lorenzo-Redondo, R., Muhomah, T., Carias, A. M., Arif, M. S., Akiso, M. M., Mureithi, M., Anzala, O., Gilmour, J., Joseph, S., & Hope, T.J. (2025). Endocervix exhibits greater susceptibility to HIV-1 infection compared to ectocervix following ex vivo exposure to Transmitted/Founder HIV-1 variants. PloS one, 20(11), e0334510. https://doi.org/10.1371/journal.pone.0334510

  • Strasser, M. K., Gibbs, D. L., Gascard, P., Bons, J., Hickey, J. W., Pan, D., Caruso, J. A., Wang, X., Chen-Tanyolac, C., Bai, R., Schürch, C. M., Tan, Y., Black, S., Chu, P., Ozkan, A., Basisty, N., Sangwan, V., Rose, J., Shah, S., Burton, J. B., …, Huang, S., Ferri, L. E. (2025). Concerted changes in Epithelium and Stroma: a multi-scale, multi-omics analysis of progression from Barrett's Esophagus to adenocarcinoma. Developmental cell, 60(20), 2807–2824.e7. https://doi.org/10.1016/j.devcel.2025.06.034

  • Luo, P. M., Ahuja, N. H., Chaney, C., Pi, D., Cwiek, A., Markowska, Z., Hiremath, C., Marciano, D. K., Hirschi, K. K., Iruela-Arispe, M.L., Carroll, T. J., & Cleaver, O. (2025). Zonal endothelial cell heterogeneity underlies murine renal vascular development. Angiogenesis, 28(4), 57. https://doi.org/10.1007/s10456-025-10000-0

  • Loiacono, A., & Huang, S. (2025). Correction: Anticancer drug development against ribosome synthesis and the nucleolus. Biochemical Society transactions, 53(5), 1431. https://doi.org/10.1042/BST20253011_COR

  • Vila Ellis, L., Cornfield, D. N., Croglio, M. P., Islam, M. N., & Meegan, J. E. (2025). From development to regeneration: the endothelial interface in lung injury and repair. American journal of physiology. Lung cellular and molecular physiology, 329(5), L658–L666. https://doi.org/10.1152/ajplung.00236.2025

  • Kim, S. K., & Gelfand, V.I. (2025). PolyQ-Expansion of Ataxin-2 Disrupts Microtubule Stability and Impairs Axon Outgrowth. The Journal of neuroscience : the official journal of the Society for Neuroscience, 45(40), e0682252025. https://doi.org/10.1523/JNEUROSCI.0682-25.2025

  • Chembazhi, U. V., Bangru, S., Dutta, R. K., Das, D., Peiffer, B., Natua, S., Toohill, K., Leona, A., Purwar, I., Bhowmik, A., Goyal, Y., Sun, Z., Diehl, A. M., & Kalsotra, A. (2025). Dysregulated RNA splicing impairs regeneration in alcohol-associated liver disease. Nature communications, 16(1), 8049. https://doi.org/10.1038/s41467-025-63251-2

  • Kooner, A., Janappareddi, A., Wan, L., Parvez, S., & Lio, P. (2025). Letter: Reduced Risk of Neurodevelopmental and Psychiatric Disorders With Dupilumab Use in Pediatric Atopic Dermatitis. Dermatitis : contact, atopic, occupational, drug, 37(1), 117–119. https://doi.org/10.1177/17103568251376644

  • Southern, R. M., Schmitz, R. L., Samaniego-Castruita, D., Balsells, D., Han, I., Ramesh, P., Tran, M. T., Montes, C., Cheong, T. C., Chiarle, R., Abraham, A., Waisman, A., Rickert, R. C., Shukla, V., & Shukla, A. (2025). IgM and IgG1 B cell receptors differentially affect B cell fates and dictate the pathogenesis of mature B cell lymphomas. Science advances, 11(35), eadp9391. https://doi.org/10.1126/sciadv.adp9391

  • Romay, M. C., Ma, F., Mompeón, A., Silvestro, M., Hernandez, G. E., Salvador, J., Wang, A. L., Vandestienne, M., Bardin, N., Blot-Chabaud, M., Leroyer, A. S., Ait-Oufella, H., Ramkhelawon, B., & Iruela-Arispe, M.L. (2025). Region-specific gene expression and sex inform about disease susceptibility in the aorta. Nature cardiovascular research, 4(9), 1152–1171. https://doi.org/10.1038/s44161-025-00692-4

  • Vogt, E. J. D., Seim, I., Snead, W.T., Curtis, B. N., & Gladfelter, A. S. (2025). Cooperativity in septin polymerization is tunable by ionic strength and membrane adsorption. Biophysical journal, S0006-3495(25)00498-9. Advance online publication. https://doi.org/10.1016/j.bpj.2025.08.005

  • Snead, W.T., Skillicorn, M. K., Shrinivas, K., & Gladfelter, A. S. (2025). Immiscible proteins compete for RNA binding to order condensate layers. Proceedings of the National Academy of Sciences of the United States of America, 122(32), e2504778122. https://doi.org/10.1073/pnas.2504778122

  • Bi, H., Ren, K., Wang, P., Li, E., Han, X., Wang, W., Yang, J., Aydemir, I., Tao, K., Ma, R., Godley, L. A., Liu, Y., Shukla, V., Bartom, E. T., Tang, Y., Blanc, L., Sukhanova, M., & Ji, P. (2025). DDX41 resolves G-quadruplexes to maintain erythroid genome integrity and prevent cGAS-mediated cell death. Nature communications, 16(1), 7195. https://doi.org/10.1038/s41467-025-62307-7

  • Vila Ellis, L., Bywaters, J. D., Ceas, A., Liu, Y., Sucre, J. M., & Chen, J. (2025). p53 maintains lineage fidelity during lung capillary injury-repair in neonatal hyperoxia. JCI insight, 10(17), e182880. https://doi.org/10.1172/jci.insight.182880

  • Loiacono, A., & Huang, S. (2025). Anticancer drug development against ribosome synthesis and the nucleolus. Biochemical Society transactions, BST20253011. Advance online publication. https://doi.org/10.1042/BST20253011

  • Manolio, T. A., Rider, R., Bult, C. J., Chisholm, R.L., Deverka, P. A., Ginsburg, G. S., Green, E. D., Jarvik, G. P., Mensah, G. A., Narula, J., Ramos, E. M., Relling, M. V., Roden, D. M., Rowley, R., Abul-Husn, N. S., Buchanan, A. H., Chute, C. G., Del Fiol, G., Elhanan, G., Haga, S. B., … Williams, M. S. (2025). Advancing the science of genomic learning healthcare systems. Learning health systems, 9(4), e70027. https://doi.org/10.1002/lrh2.70027

  • Pi, D., Braun, J., Dutta, S., Patra, D., Bougaran, P., Mompeón, A., Ma, F., Stock, S. R., Choi, S., García-Ortega, L., Pratama, M. Y., Pichardo, D., Ramkhelawon, B., Benedito, R., Bautch, V. L., Ornitz, D. M., Goyal, Y., & Iruela-Arispe, M.L. (2025). Resolving the design principles that control post-natal vascular growth and scaling. Cell systems, 16(7), 101324. https://doi.org/10.1016/j.cels.2025.101324

  • Akiso, M. M., Abook, I., Mureithi, M. W., Kombo, J., Koi, P., Musando, J., Chirchir, R. J., McRaven, M. D., Carias, A. M., Joseph, S., Anzala, O., & Hope, T.J. (2025). Vaginal microbiome dysbiosis and sexually transmitted infections correlate with concentrations of immunoglobulin isotypes in human cervicovaginal mucus: insights into HIV-1 transmission. Frontiers in immunology, 16, 1627807. https://doi.org/10.3389/fimmu.2025.1627807

  • Siddique, M. A., McRaven, M. D., Arif, M. S., Allen, E. J., McKee, C., Honne, S., Sultana, T., Kim, B., C arias, A. M., Mamede, J. I., & Hope, T.J. (2025). Blockade of de novo dNTP biosynthesis pathway delays HIV-1 early life cycle kinetics and dynamics. mBio, 16(8), e0104725. https://doi.org/10.1128/mbio.01047-25

  • Sheridan, J., Grata, A., Dorr, J., Suva, E.E., Bresteau, E., Mitchell, L.R., Hassan, O., & Mitchell, B. (2025). Corrigendum to "Centriolar defects underlie a primary ciliary dyskinesia phenotype in an adenylate kinase 7 deficient ciliated epithelium" [Dev. Biol. 524 (2025) 152-161]. Developmental biology, 525, 317–318. https://doi.org/10.1016/j.ydbio.2025.06.019

  • Bresteau, E., Suva, E.E., Revell, C., Hassan, O. A., Grata, A., Sheridan, J., Mitchell, J., Arvanitis, C., Korobova, F., Woolner, S., Jensen, O. E., & Mitchell, B. (2025). Apical size reduction by macropinocytosis alleviates tissue crowding. Nature communications, 16(1), 5338. https://doi.org/10.1038/s41467-025-60724-2 

  • Snead W.T. (2025). Condensate-membrane interactions shape membranes, tune cytoskeletal assembly, and localize mRNAs. Current opinion in cell biology, 95, 102540. https://doi.org/10.1016/j.ceb.2025.102540

  • Sheridan, J., Grata, A., Dorr, J., Suva, E. E., Bresteau, E., Mitchell, L. R., Hassan, O., & Mitchell, B. (2025). Centriolar defects underlie a primary ciliary dyskinesia phenotype in an adenylate kinase 7 deficient ciliated epithelium. Developmental biology, 524, 152–161. https://doi.org/10.1016/j.ydbio.2025.05.011

  • Lu, W., Lee, B. S., Deng, H. X. Y., Lakonishok, M., Martin-Blanco, E., & Gelfand, V.I. (2025). 'Mitotic' kinesin-5 is a dynamic brake for axonal growth in Drosophila. Development (Cambridge, England), 152(9), dev204424. https://doi.org/10.1242/dev.204424

  • Gerner-Mauro, K. N., Vila Ellis, L., Wang, G., Nayak, R., Lwigale, P. Y., Poché, R. A., & Chen, J. (2025). Morphogenic, molecular and cellular adaptations for unidirectional airflow in the chicken lung. Development (Cambridge, England), 152(8), dev204346. https://doi.org/10.1242/dev.204346

  • Iruela-Arispe M.L. (2025). Unveiling the cholesterol-hemangioma axis: a path to new treatments. The Journal of clinical investigation, 135(7), e193039. https://doi.org/10.1172/JCI193039

  • Huang, S., Soto, A. M., & Sonnenschein, C. (2025). The end of the genetic paradigm of cancer. PLoS biology, 23(3), e3003052. https://doi.org/10.1371/journal.pbio.3003052

  • Alpay, E. E., Zinani, O. Q. H., Hu, X., Ay, A., & Özbudak, E.M. (2025). DeltaC and DeltaD ligands play different roles in the segmentation clock dynamics. Nature communications, 16(1), 2413. https://doi.org/10.1038/s41467-025-57645-5

  • Renganathan, B., Moore, A. S., Yeo, W. H., Petruncio, A., Ackerman, D., Weigel, A. V., Team, T. C., Pasolli, H. A., Xu, C. S., Shtengel, G., Hess, H. F., Serpinskaya, A. S., Zhang, H. F., Lippincott-Schwartz, J., & Gelfand, V.I. (2025). Vimentin filament transport and organization revealed by single-particle tracking and 3D FIB-SEM. The Journal of cell biology, 224(4), e202406054. https://doi.org/10.1083/jcb.202406054

  • Simsek, M. F., Saparov, D., Keseroglu, K., Zinani, O., Chandel, A. S., Dulal, B., Sharma, B. K., Zimik, S., & Özbudak, E.M. (2025). The vertebrate segmentation clock drives segmentation by stabilizing Dusp phosphatases in zebrafish. Developmental cell, 60(5), 669–678.e6. https://doi.org/10.1016/j.devcel.2024.11.003

  • Carias, A. M., Anderson, M., McRaven, M., Allen, E., Fought, A. J., & Hope, T.J. (2025). Transcytosis as a Mechanism of HIV-1 Entry into Columnar Epithelial Explants of the Female Reproductive Tract. AIDS research and human retroviruses, 41(3), 167–173. https://doi.org/10.1089/aid.2024.0045

  • Spurgin, S., Nguimtsop, A. M., Chaudhry, F. N., Michki, S. N., Salvador, J., Iruela-Arispe, M.L., Zepp, J. A., Mukhopadhyay, S., & Cleaver, O. (2025). Dynamics of primary cilia in endothelial and mesenchymal cells throughout mouse lung development. Developmental dynamics : an official publication of the American Association of Anatomists, 254(11), 1187–1202. https://doi.org/10.1002/dvdy.70008

  • Basu, A., Krug, T., du Pont, B., Huang, Q., Sun, S., Adam, S.A., Goldman, R.D., Weitz, D. A. (2025). Vimentin undergoes liquid–liquid phase separation to form droplets which wet and stabilize actin fibers. Proceedings of the National Academy of Sciences, 122(10), e2418624122. https://doi.org/10.1073/pnas.2418624122 

  • Feuermann, M., Mi, H., Gaudet, P., Muruganujan, A., Lewis, S. E., Ebert, D., Mushayahama, T., Gene Ontology Consortium [including Chisholm, R.L.], & Thomas, P. D. (2025). A compendium of human gene functions derived from evolutionary modelling. Nature, 640(8057), 146–154. https://doi.org/10.1038/s41586-025-08592-0

2024

  • Gould, A., Luan, Y., Hou, Y., Korobova, F.V., Chen, L., Arrieta, V. A., Amidei, C., Ward, R., Gomez, C., Castro, B., Habashy, K., Zhang, D., Youngblood, M., Dmello, C., Bebawy, J., Bouchoux, G., Stupp, R., Canney, M., Yue, F., Iruela-Arispe, M.L., … Sonabend, A. M. (2024). Endothelial response to blood-brain barrier disruption in the human brain. JCI insight, 10(4), e187328. https://doi.org/10.1172/jci.insight.187328

  • Sun, H., Kumari, N., Melzer, M.E., Backman, V., Goyal, Y. (2025). Navigating Nongenetic Plasticity in Cancer Drug Resistance. Annual Review Cancer Biology. 9:245-266. https://doi.org/10.1146/annurev-cancerbio-071924-084617

  • Manolio, T. A., Narula, J., Rupert, A., Bult, C. J., Chisholm, R.L., Ginsburg, G. S., Green, E. D., Hooker, G., Jarvik, G. P., Mensah, G. A., Ramos, E. M., Roden, D. M., Rowley, R., Taylor, C. O., & Williams, M. S. (2024). Genomic medicine year in review: 2024. American journal of human genetics, 111(12), 2585–2588. https://doi.org/10.1016/j.ajhg.2024.11.002

  • McCabe, M., Boya, P., Chen, R. H., Chu, C. T., Colombo, M. I., Delgui, L., Eskelinen, E. L., Hamasaki, M., Hansen, M., He, C., Jäättelä, M., Kimchi, A., Kraft, C., Kundu, M., Melendez, A., Pattingre, S., Proikas-Cezanne, T., Sebti, S., Simon, A. K., Simonsen, A., … Cuervo, A. M. (2024). Women in Autophagy: an initiative to promote gender parity in science. Nature cell biology, 26(12), 2009–2012. https://doi.org/10.1038/s41556-024-01566-w

  • Kono, Y., Pack, C. G., Ichikawa, T., Komatsubara, A., Adam, S.A., Miyazawa, K., Rolas, L., Nourshargh, S., Medalia, O., Goldman, R. D., Fukuma, T., Kimura, H., & Shimi, T. (2024). Roles of the lamin A-specific tail region in the localization to sites of nuclear envelope rupture. PNAS nexus, 3(12), pgae527. https://doi.org/10.1093/pnasnexus/pgae527

  • Kim, S. K., Rogers, S. L., Lu, W., Lee, B. S., & Gelfand, V.I. (2024). EB-SUN, a new microtubule plus-end tracking protein in Drosophila. Molecular biology of the cell, 35(12), ar147. https://doi.org/10.1091/mbc.E24-09-0402

  • Taylor, R. A., Xiao, S., Carias, A. M., McRaven, M. D., Thakkar, D. N., Araínga, M., Lorenzo-Redondo, R., Allen, E. J., Rogers, K. A., Kumarapperuma, S. C., Gong, S., Anderson, M. R., Thomas, Y., Madden, P. J., Corti, D., Cameroni, E., Lanzavecchia, A., Goins, B., Fox, P., Villinger, F. J., … Hope, T.J. (2024). PET/CT Targeted Tissue Sampling Reveals Intravenously Administered HGN194 IgG1 Affects HIV Distribution after Rectal Exposure. AIDS research and human retroviruses, 40(11), 637–648. https://doi.org/10.1089/AID.2024.0019

  • Becker, M. E., Martin-Sancho, L., Simons, L. M., McRaven, M. D., Chanda, S. K., Hultquist, J. F., & Hope, T.J. (2024). Live imaging of airway epithelium reveals that mucociliary clearance modulates SARS-CoV-2 spread. Nature communications, 15(1), 9480. https://doi.org/10.1038/s41467-024-53791-4

  • Kim, B., Huang, Y., Ko, K. P., Zhang, S., Zou, G., Zhang, J., Kim, M. J., Little, D., Ellis, L.V., Paschini, M., Jun, S., Park, K. S., Chen, J., Kim, C., & Park, J. I. (2024). PCLAF-DREAM drives alveolar cell plasticity for lung regeneration. Nature communications, 15(1), 9169. https://doi.org/10.1038/s41467-024-53330-1

  • Lee, Y. J., Koch, M., Karl, D., Torres-Collado, A. X., Fernando, N. T., Rothrock, C., Kuruppu, D., Ryeom, S., Iruela-Arispe, M.L., & Yoon, S. S. (2024). Retraction: Variable Inhibition of Thrombospondin 1 against Liver and Lung Metastases through Differential Activation of Metalloproteinase ADAMTS1. Cancer research, 84(20), 3491. https://doi.org/10.1158/0008-5472.CAN-24-3247

  • Kim, J., Bose, D., Araínga, M., Haque, M. R., Fennessey, C. M., Caddell, R. A., Thomas, Y., Ferrell, D. E., Ali, S., Grody, E., Goyal, Y., Cicala, C., Arthos, J., Keele, B. F., Vaccari, M., Lorenzo-Redondo, R., Hope, T.J., Villinger, F., & Martinelli, E. (2024). Publisher Correction: TGF-β blockade drives a transitional effector phenotype in T cells reversing SIV latency and decreasing SIV reservoirs in vivo. Nature communications, 15(1), 8787. https://doi.org/10.1038/s41467-024-52897-z

  • Tagliaferri Rael, C., Giguere, R., Bryndza Tfaily, E., Sutton, S., Horn, E., Schieffer, R. J., Hendrix, C., D'Aquila, R. T., & Hope, T.J. (2024). The Global Impact of Diversifying PrEP Options: Results of an International Discrete Choice Experiment of Existing and Potential PrEP Strategies with Gay and Bisexual Men and Physicians. AIDS research and human retroviruses, 40(10), 591–605. https://doi.org/10.1089/AID.2023.0120

  • Fakhari, H., Scherr, C. L., Moe, S., Hoell, C., Smith, M. E., Rasmussen-Torvik, L. J., Chisholm, R.L., & McNally, E. M. (2024). From Calculation to Communication: Using Risk Score Calculators to Inform Clinical Decision Making and Facilitate Patient Engagement. Medical decision making : an international journal of the Society for Medical Decision Making, 44(8), 900–913. https://doi.org/10.1177/0272989X241285036

  • Moise, K., Arun, K. M., Pillai, M., Salvador, J., Mehta, A. S., Goyal, Y., & Iruela-Arispe, M. L. (2024). Endothelial cell elongation and alignment in response to shear stress requires acetylation of microtubules. Frontiers in physiology, 15, 1425620. https://doi.org/10.3389/fphys.2024.1425620

  • IGVF Consortium [including Chisholm, R.L.] (2024). Deciphering the impact of genomic variation on function. Nature, 633(8028), 47–57. https://doi.org/10.1038/s41586-024-07510-0

  • Ma, J., Zhang, W., Rahimialiabadi, S., Ganesh, N. U., Sun, Z., Parvez, S., Peterson, R. T., & Yeh, J. J. (2024). Instantaneous visual genotyping and facile site-specific transgenesis via CRISPR-Cas9 and phiC31 integrase. Biology open, 13(9), bio061666. https://doi.org/10.1242/bio.061666

  • Abraham, A., Samaniego-Castruita, D., Han, I., Ramesh, P., Tran, M. T., Paladino, J., Kligfeld, H., Morgan, R. C., Schmitz, R. L., Southern, R. M., Shukla, A., & Shukla, V. (2024). Arid1a-dependent canonical BAF complex suppresses inflammatory programs to drive efficient germinal center B cell responses. Nature immunology, 25(9), 1704–1717. https://doi.org/10.1038/s41590-024-01920-y

  • Mellis, I. A., Melzer, M. E., Bodkin, N., & Goyal, Y. (2024). Prevalence of and gene regulatory constraints on transcriptional adaptation in single cells. Genome biology, 25(1), 217. https://doi.org/10.1186/s13059-024-03351-2

  • Zhang, Z., Melzer, M. E., Arun, K. M., Sun, H., Eriksson, C. J., Fabian, I., Shaashua, S., Kiani, K., Oren, Y., & Goyal, Y. (2024). Synthetic DNA barcodes identify singlets in scRNA-seq datasets and evaluate doublet algorithms. Cell genomics, 4(7), 100592. https://doi.org/10.1016/j.xgen.2024.100592

  • Karim, A. S., Brown, D. M., Archuleta, C. M., Grannan, S., Aristilde, L., Goyal, Y., Leonard, J. N., Mangan, N. M., Prindle, A., Rocklin, G. J., Tyo, K. J., Zoloth, L., Jewett, M. C., Calkins, S., Kamat, N. P., Tullman-Ercek, D., & Lucks, J. B. (2024). Deconstructing synthetic biology across scales: a conceptual approach for training synthetic biologists. Nature communications, 15(1), 5425. https://doi.org/10.1038/s41467-024-49626-x

  • Lewis, A. C. F., Chisholm, R.L., Connolly, J. J., Esplin, E. D., Glessner, J., Gordon, A., Green, R. C., Hakonarson, H., Harr, M., Holm, I. A., Jarvik, G. P., Karlson, E., Kenny, E. E., Kottyan, L., Lennon, N., Linder, J. E., Luo, Y., Martin, L. J., Perez, E., Puckelwartz, M. J., … Fullerton, S. M. (2024). Managing differential performance of polygenic risk scores across groups: Real-world experience of the eMERGE Network. American journal of human genetics, 111(6), 999–1005. https://doi.org/10.1016/j.ajhg.2024.04.005

  • Phan, L. M. U., Yeo, W. H., Zhang, H. F., & Huang, S. (2024). Dynamic chromosome association with nuclear organelles in living cells. Histochemistry and cell biology, 162(1-2), 149–159. https://doi.org/10.1007/s00418-024-02288-8

  • Gambut, S., Hope, T.J., & Mamede, J. I. (2024). Infectious Virus Tracking by Fluorescent Live Cell Imaging in Primary Cells. Methods in molecular biology (Clifton, N.J.), 2807, 3–14. https://doi.org/10.1007/978-1-0716-3862-0_1

  • Chandel, A. S., Keseroglu, K., & Özbudak, E.M. (2024). Oscillatory control of embryonic development. Development (Cambridge, England), 151(9), dev202191. https://doi.org/10.1242/dev.202191

  • Luo, Y., Mao, C., Sanchez-Pinto, L. N., Ahmad, F. S., Naidech, A., Rasmussen, L., Pacheco, J. A., Schneider, D., Mithal, L. B., Dresden, S., Holmes, K., Carson, M., Shah, S. J., Khan, S., Clare, S., Wunderink, R. G., Liu, H., Walunas, T., Cooper, L., Yue, F., …, Chisholm, R.L., Kho, A. (2024). Northwestern University resource and education development initiatives to advance collaborative artificial intelligence across the learning health system. Learning health systems, 8(3), e10417. https://doi.org/10.1002/lrh2.10417

  • Iruela-Arispe M.L. (2024). Hemodynamic Forces and Atherosclerosis: HEG1 at the Center of the Jigsaw Puzzle. Circulation, 149(15), 1202–1204. https://doi.org/10.1161/CIRCULATIONAHA.124.067882

  • Kligfeld, H., Han, I., Abraham, A., & Shukla, V. (2024). Alternative DNA structures in hematopoiesis and adaptive immunity. Advances in immunology, 161, 109–126. https://doi.org/10.1016/bs.ai.2024.03.002

  • Koparir, A., Lekszas, C., Keseroglu, K., Rose, T., Rappl, L., Rad, A., Maroofian, R., Narendran, N., Hasanzadeh, A., Karimiani, E. G., Boschann, F., Kornak, U., Klopocki, E., Özbudak, E.M., Vona, B., Haaf, T., & Liedtke, D. (2024). Zebrafish as a model to investigate a biallelic gain-of-function variant in MSGN1, associated with a novel skeletal dysplasia syndrome. Human genomics, 18(1), 23. https://doi.org/10.1186/s40246-024-00593-w

  • Hu, J., Korchina, V., Zouk, H., Harden, M. V., Murdock, D., Macbeth, A., Harrison, S. M., Lennon, N., Kovar, C., Balasubramanian, A., Zhang, L., Chandanavelli, G., Pasham, D., Rowley, R., Wiley, K., Smith, M. E., Gordon, A., Jarvik, G. P., Sleiman, P., Kelly, M. A., … eMERGE III consortium [including Chisholm, R.L.] … Muzny, D. M. (2024). Genetic sex validation for sample tracking in next-generation sequencing clinical testing. BMC research notes, 17(1), 62. https://doi.org/10.1186/s13104-024-06723-w

  • Jain, N., Goyal, Y., Dunagin, M. C., Cote, C. J., Mellis, I. A., Emert, B., Jiang, C. L., Dardani, I. P., Reffsin, S., Arnett, M., Yang, W., & Raj, A. (2024). Retrospective identification of cell-intrinsic factors that mark pluripotency potential in rare somatic cells. Cell systems, 15(2), 109–133.e10. https://doi.org/10.1016/j.cels.2024.01.001

  • Kim, J., Bose, D., Araínga, M., Haque, M. R., Fennessey, C. M., Caddell, R. A., Thomas, Y., Ferrell, D. E., Ali, S., Grody, E., Goyal, Y., Cicala, C., Arthos, J., Keele, B. F., Vaccari, M., Lorenzo-Redondo, R., Hope, T.J., Villinger, F., & Martinelli, E. (2024). TGF-β blockade drives a transitional effector phenotype in T cells reversing SIV latency and decreasing SIV reservoirs in vivo. Nature communications, 15(1), 1348. https://doi.org/10.1038/s41467-024-45555-x

  • Nwagbo, U., Parvez, S., Maschek, J. A., & Bernstein, P. S. (2024). Elovl4b knockout zebrafish as a model for ocular very-long-chain PUFA deficiency. Journal of lipid research, 65(3), 100518. https://doi.org/10.1016/j.jlr.2024.100518

  • Hao, Q., Liu, M., Daulatabad, S. V., Gaffari, S., Song, Y. J., Srivastava, R., Bhaskar, S., Moitra, A., Mangan, H., Tseng, E., Gilmore, R. B., Frier, S. M., Chen, X., Wang, C., Huang, S., Chamberlain, S., Jin, H., Korlach, J., McStay, B., Sinha, S., … Prasanth, K. V. (2024). Monoallelically expressed noncoding RNAs form nucleolar territories on NOR-containing chromosomes and regulate rRNA expression. eLife, 13, e80684. https://doi.org/10.7554/eLife.80684

  • Ferreira, A., Harter, A., Afreen, S., Kanai, K., Batori, S., & Redei, E. E. (2024). The WMI Rat of Premature Cognitive Aging Presents Intrinsic Vulnerability to Oxidative Stress in Primary Neurons and Astrocytes Compared to Its Nearly Isogenic WLI Control. International journal of molecular sciences, 25(3), 1692. https://doi.org/10.3390/ijms25031692

  • Luchniak, A., Roy, P. S., Kumar, A., Schneider, I. C., Gelfand, V.I., Jernigan, R. L., & Gupta, M. L., Jr (2024). Tubulin CFEOM mutations both inhibit or activate kinesin motor activity. Molecular biology of the cell, 35(3), ar32. https://doi.org/10.1091/mbc.E23-01-0020

  • Makeyev, E. V., & Huang, S. (2024). The perinucleolar compartment: structure, function, and utility in anti-cancer drug development. Nucleus (Austin, Tex.), 15(1), 2306777. https://doi.org/10.1080/19491034.2024.2306777

  • McDaniel, C., Simsek, M. F., Chandel, A. S., & Özbudak, E.M. (2024). Spatiotemporal control of pattern formation during somitogenesis. Science advances, 10(4), eadk8937. https://doi.org/10.1126/sciadv.adk8937

  • Dutta, S., Farhadifar, R., Lu, W., Kabacaoğlu, G., Blackwell, R., Stein, D. B., Lakonishok, M., Gelfand, V.I., Shvartsman, S. Y., & Shelley, M. J. (2024). Self-organized intracellular twisters. Nature Physics, 20, 666-674. https://doi.org/10.1038/s41567-023-02372-1

  • Sunshine, H. L., Cicchetto, A. C., Kaczor-Urbanowicz, K. E., Ma, F., Pi, D., Symons, C., Turner, M., Shukla, V., Christofk, H. R., Vallim, T. A., & Iruela-Arispe, M.L. (2024). Endothelial Jagged1 levels and distribution are post-transcriptionally controlled by ZFP36 decay proteins. Cell reports, 43(1), 113627. https://doi.org/10.1016/j.celrep.2023.113627

  • Paudel, B., Jeong, S. Y., Martinez, C. P., Rickman, A., Haluck-Kangas, A., Bartom, E. T., Fredriksen, K., Affaneh, A., Kessler, J. A., Mazzulli, J. R., Murmann, A. E., Rogalski, E., Geula, C., Ferreira, A., Heckmann, B. L., Green, D. R., Sadleir, K. R., Vassar, R., & Peter, M. E. (2024). Death Induced by Survival gene Elimination (DISE) correlates with neurotoxicity in Alzheimer's disease and aging. Nature communications, 15(1), 264. https://doi.org/10.1038/s41467-023-44465-8

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