Below is a list of active research projects at CAHRA. Click on each project for a full description and contact information.
This longitudinal cohort study, now in its 15th year, will provide an in-depth investigation of older adults’ health literacy and ability to manage health, and whether these skills are affected by cognitive decline and the aging process.
This supplement to the LitCog study explores the experiences of patients' caregivers to identify modifiable factors that could be targeted by health system interventions supporting families affected by ADRD.
LitCog Plan Your Lifespan
The goal of this study is to better understand how older adult aging-in-place decision making and implementation is impacted by age-related changes (e.g. cognition, function, chronic condition), social influences, and environmental factors
The objective of the MidCog study is to investigate how health literacy (HL), self-management (SM) skills, and psychosocial factors may evolve over the adult life course and affect cognitive and health outcomes in older age.
This is a project to develop a brief set of cognitive impairment screening measures for use in diverse settings and populations. Measures are drawn from the NIH Toolbox for Assessment of Neurological and Behavioral Function and implemented as a downloadable app.
Responding to increasing calls for early detection of cognitive impairment in everyday clinical settings, our trial will offer primary care providers serving affordable, scalable means to detect and care for those affected, while also addressing known disparities.
This project aims to implement and evaluate a user-centered, scalable, telemedicine-linked strategy for the routine detection of cognitive decline during the Annual Wellness Visit. MyCog Mobile will leverage well-validated measures from The NIH Toolbox for Assessment of Neurological and Behavioral Function® Cognition battery.
This clinical trial will implement and evaluate an app-based, electronic health record (EHR)-linked cognitive screening strategy for the routine detection of cognitive decline among diverse primary care settings.
With healthcare costs related to liver transplantation expected to increase in the future, more information is needed to help fill critical gaps in understanding how to help improve health outcomes post-transplantation.
The C3 Study
The C3 study will extend an active NIA cohort study of diverse, middle age and older adults with one or more chronic conditions to assess COVID-19’s long-term and disparate impact on health and healthcare experiences.
This clinical trial will study how readily available technology-enabled tools combined with transplant center resources and care partner support can optimize medication adherence, quality of life, and health outcomes among new liver transplant recipients (LTRs) at 3 diverse centers.
STEP-UP aims to test the effectiveness compared with usual care and investigate the heterogeneity of STEP-UP intervention effects. The project will assess the reach, adoption, implementation, maintenance, and costs of STEP-UP components.
This project will develop and validate state-of-the-art machine learning algorithms using data from the EHR and audio-recorded primary care encounters to identify patients with cognitive impairment.
This project tests the effectiveness and fidelity of an American College of Physicians diabetes health literacy intervention as delivered by health coaches within patient-centered medical homes in rural Arkansas.
This study examines the strategies employed by older adults with ADRD and their caregivers to self-manage multidrug regimens as the disease progresses over time.
Medcare - LitCog
For this study, we are seeking to understand how older adults manage all of their medications. We are also interested in how they may or may not work with family members and friends (support partners) to manage medications.
We will conduct qualitative interviews with 25 primary care clinicians to explore strategies primary care clinicians use to facilitate medication management among older adults with dementia and their caregivers. This research will also seek to characterize any challenges that primary care clinicians face when interacting with this patient population.
This project will test the effectiveness of Promoting REproductive Planning And REadiness in Diabetes (PREPARED), against usual care, to improve patient knowledge of reproductive risks and recommended self-care activities, engagement in diabetes self-management behaviors, and glycemic control.
Eli Lilly EMC2 Diagnostics
This project aims to tailor our developed Electronic Health Record (EHR) Medication Complete Communication (EMC2) strategy to promote patient education and informed decision making whenever biomarker testing might inform the choice of treatment among patients with advanced or metastatic non-small cell lung cancer.