Research Projects
Below is a list of active research projects at CAHRA. Click on each project for a full description and contact information.

LitCog
This longitudinal cohort study, now in its 15th year, will provide an in-depth investigation of older adults’ health literacy and ability to manage health, and whether these skills are affected by cognitive decline and the aging process.

LitCog Caregiver
This supplement to the LitCog study explores the experiences of patients' caregivers to identify modifiable factors that could be targeted by health system interventions supporting families affected by ADRD.

LitCog COVID Supplement
This investigation examines the impact of COVID-19 among older individuals and how lifestyle & self-management behaviors, healthcare use, patient-reported and clinical outcomes may change over time.

LitCog Plan Your Lifespan
The goal of this study is to better understand how older adult aging-in-place decision making and implementation is impacted by age-related changes (e.g. cognition, function, chronic condition), social influences, and environmental factors

MidCog
The objective of the MidCog study is to investigate how health literacy (HL), self-management (SM) skills, and psychosocial factors may evolve over the adult life course and affect cognitive and health outcomes in older age.

MyCog
This is a project to develop a brief set of cognitive impairment screening measures for use in diverse settings and populations. Measures are drawn from the NIH Toolbox for Assessment of Neurological and Behavioral Function and implemented as a downloadable app.

MyCog Mobile
This project aims to implement and evaluate a user-centered, scalable, telemedicine-linked strategy for the routine detection of cognitive decline during the Annual Wellness Visit. MyCog Mobile will leverage well-validated measures from The NIH Toolbox for Assessment of Neurological and Behavioral Function® Cognition battery.

Toolbox Detect
This clinical trial will implement and evaluate an app-based, electronic health record (EHR)-linked cognitive screening strategy for the routine detection of cognitive decline among diverse primary care settings.

EASI-Cog
This project will develop and validate state-of-the-art machine learning algorithms using data from the EHR and audio-recorded primary care encounters to identify patients with cognitive impairment.

REMinD
This clinical trial assesses the use of the Universal Medication Schedule (UMS) and consumer technologies to standardize the prescribing and dispensing of Rx diabetes medications.

UAMS
This project tests the effectiveness and fidelity of an American College of Physicians diabetes health literacy intervention as delivered by health coaches within patient-centered medical homes in rural Arkansas.

TAKE IT
This clinical trial tests a nurse-led, patient-centered, technology-enabled medication self-management intervention to improve regimen adherence and clinical outcomes among new kidney transplant recipients.

GBMF TEAM
This project aims to improve primary care-based medication therapy management for older adults with complex Rx regimens by enlisting the support of community pharmacies and linking them to primary care via our Technology-Enabled Alliance for Medication Therapy Management (TEAM) intervention.

RRF Promoting COVID-19 Vaccination
With this service grant, we will develop, implement, and evaluate persuasive COVID-19 vaccine messaging for older, English and Spanish-speaking Latinx adults.

Merck Digital HL
This project supports development and testing of a new health literacy assessment that can be delivered and completed by patients via the internet or SMS text messages.

MedCare
This study examines the strategies employed by older adults with ADRD and their caregivers to self-manage multidrug regimens as the disease progresses over time.

Medcare - LitCog
For this study, we are seeking to understand how older adults manage all of their medications. We are also interested in how they may or may not work with family members and friends (support partners) to manage medications.

Medcare Clinician
We will conduct qualitative interviews with 25 primary care clinicians to explore strategies primary care clinicians use to facilitate medication management among older adults with dementia and their caregivers. This research will also seek to characterize any challenges that primary care clinicians face when interacting with this patient population.

Prepared
This project will test the effectiveness of Promoting REproductive Planning And REadiness in Diabetes (PREPARED), against usual care, to improve patient knowledge of reproductive risks and recommended self-care activities, engagement in diabetes self-management behaviors, and glycemic control.

Eli Lilly EMC2 Diagnostics
This project aims to tailor our developed Electronic Health Record (EHR) Medication Complete Communication (EMC2) strategy to promote patient education and informed decision making whenever biomarker testing might inform the choice of treatment among patients with advanced or metastatic non-small cell lung cancer.