Pediatrics
Diana Bowen LabStudying the process of patient transition from pediatric to adult care
Studying the process of patient transition from pediatric to adult care
Research Description
Dr. Bowen's research is focused in pediatric urology with a specific interest in care of patients with neurogenic bladder. Her previous research aimed to understand the long-term fate of the neurogenic bladder in high-risk spina bifida patients in addition to basic science research focused on bladder outlet obstruction in mice and resultant hypertrophy of the bladder muscle.
Publications
- Bowen DK, Cheng EY, Hirsch J, Huang J, Meyer T, Rosoklija I, Chu DI, Yerkes EB. A fresh "slant" on modified Mitchell bladder neck reconstruction: A contemporary single-institution experience. Front Pediatr. 2022 Sep 2;10:933481.
- Bowen DK, Meyer T, Rosoklija I, Sturm R, Chu DI, Cheng EY, Yerkes EB. Botulinum toxin in patients at-risk for bladder augmentation: Durable impact or kicking the can? Neurourol Urodyn. 2022 Aug;41(6):1406-1413.
- Bowen DK, Balmert LC, Meyer T, Rosoklija I, Hodgkins KS, Ghossein C, Cheng EY, Yerkes EB, Isakova T, Chu DI. Variability in Kidney Function Estimates in Emerging Adults With Spina Bifida: Implications for Transitioning From Pediatric to Adult Care. Urology. 2021 Feb;148:306-313.
Contact
Find contact information on Dr. Bowen's faculty profile. Earl Cheng LabConducting bladder tissue engineering research
Conducting bladder tissue engineering research
Research Description
Dr. Cheng is a national expert in complex reconstructive urology and co-directs a basic science laboratory with Arun Sharma, PhD, that focuses on tissue engineering techniques for the urinary tract, with emphasis on bladder regeneration. He also has a special interest in the medical and surgical management of individuals with sex development conditions that can result in ambiguous genitalia.
Publications
- Faasse MA, Farhat WA, Rosoklija I, Shannon R, Odeh RI, Yoshiba GM, Zu'bi F, Balmert LC, Liu DB, Alyami FA, Beaumont JL, Erickson DL, Gong EM, Johnson EK, Judd S, Kaplan WE, Kaushal G, Koyle MA, Lindgren BW, Maizels M, Marcus CR, McCarter KL, Meyer T, Qureshi T, Saunders M, Thompson T, Yerkes EB, Cheng EY. Randomized trial of prophylactic antibiotics vs. placebo after midshaft-to-distal hypospadias repair: the PROPHY Study. J Pediatr Urol. 2022 Apr;18(2):171-177.
- Tanaka ST, Yerkes EB, Routh JC, Tu DD, Austin JC, Wiener JS, Vasquez E, Joseph DB, Ahn JJ, Wallis MC, Williams T, Rose C, Baum MA, Cheng EY. Urodynamic characteristics of neurogenic bladder in newborns with myelomeningocele and refinement of the definition of bladder hostility: Findings from the UMPIRE multi-center study. J Pediatr Urol. 2021 Oct;17(5):726-732.
- Chan YY, D'Oro A, Yerkes EB, Rosoklija I, Balmert LC, Lindgren BW, Gong EM, Liu DB, Johnson EK, Chu DI, Cheng EY. Challenging proximal hypospadias repairs: An evolution of technique for two stage repairs.J Pediatr Urol. 2021 Apr; 17(2): 225.e1-225.e8.
- Johnson EK, Jacobson DL, Finlayson C, Yerkes EB, Goetsch AL, Leeth EA, Cheng EY. Proximal Hypospadias-Isolated Genital Condition or Marker of More? The Journal of urology. August 2020.
Contact
For contact information, view Dr. Cheng's faculty profile. David Chu LabInvestigating chronic kidney disease diagnosis and management in congenital and acquired urologic conditions, clinical care variation, and preventable readmissions and complications following surgery.
Investigating chronic kidney disease diagnosis and management in congenital and acquired urologic conditions, clinical care variation, and preventable readmissions and complications following surgery.
Research Description
Dr. Chu is interested in spina bifida research; surgical health disparities; surgical quality improvement; and chronic kidney disease.
Publications
- Rague JT, Kim S, Hirsch J, Meyer T, Rosoklija I, Larson JE, Swaroop VT, Bowman R, Bowen DK, Cheng EY, Gordon EJ, Holmbeck G, Chu DI, Isakova T, Yerkes EB, Chu DI. The association of health literacy with health-related quality of life in youth and young adults with spina bifida: A cross-sectional study. J Pediatr. 2022 Aug 12:S0022-3476(22)00712-0.
- Rague JT, Kim S, Hirsch JA, Meyer T, Rosoklija I, Larson JE, Swaroop VT, Bowman RM, Bowen DK, Cheng EY, Gordon EJ, Chu DI, Isakova T, Yerkes EB, Chu DI. Assessment of Health Literacy and Self-reported Readiness for Transition to Adult Care Among Adolescents and Young Adults With Spina Bifida. JAMA Netw Open. 2021 Sep; 4(9): e2127034.
- Chu DI, Balmert LC, Chen L, Arkin C, Meyer T, Rosoklija I, Bowen DK, Hodgkins KS, Bowman RM, Cheng EY, Yerkes EB, Isakova T. Diagnostic Test Characteristics of Ultrasound Based Hydronephrosis in Identifying Low Kidney Function in Young Patients with Spina Bifida: A Retrospective Cohort Study. J Urol. 2021 Apr; 205(4): 1180-1188.
- Chu DI, Liu T, Patel P, Routh JC, Ouyang L, Baum MA, Cheng EY, Yerkes EB, Isakova T. Kidney Function Surveillance in the National Spina Bifida Patient Registry: A Retrospective Cohort Study. The Journal of urology. September 2020.
- Yerkes EB, Baum M, Chu DI. Chronic kidney disease and upper tract concerns after congenital and acquired urinary tract abnormalities: considerations for transition of care in teens and young adults. World Journal of Urology. January 2020.
- Kim S, Balmert L, Raval MV, Johnson EK, Abdullah F, Chu DI. Association of number and type of serious complications with failure to rescue in children undergoing surgery: A NSQIP-Pediatric analysis. Journal of Pediatric Surgery. January 2020.
Contact
Find contact information on Dr. Chu's faculty profile. Edward Gong LabStudying the mechanisms behind pathologic bladder degeneration
Studying the mechanisms behind pathologic bladder degeneration
Research Description
Bladder dysfunction from obstruction or denervation is the cause of kidney failure in many pediatric patients. Dr. Gong leads research to determine mechanisms behind pathologic bladder degeneration. His goal is to develop therapeutic agents that can prevent loss of bladder function and promote regeneration of healthy bladder tissue in children affected by posterior urethral valves or neurogenic bladder.
Publications
- Rague JT, Shannon R, Rosoklija I, Lindgren BW, Gong EM. Robot-assisted laparoscopic urologic surgery in infants weighing ≤10 kg: A weight stratified analysis. J Pediatr Urol. 2021 Dec;17(6):857.e1-857.e7.
- Tassone NM, Li B, Patel MS, Devine MY, Firmiss PR, Gould AD, Kochan KS, Stubbee RA, Bowen DK, Dettman RW, Gong EM. Stem cell antigen/Ly6a protects against bladder fibrosis in mice. American Journal of Physiology - Renal Physiology. December 2019.
- Morrison CD, Shannon R, Rosoklija I, Nettey OS, Superina R, Cheng EY, Gong EM. Ureteral Complications of Pediatric Renal Transplantation. Journal of Urology. April 2019.
- Li B, Liu DB, Gong EM. Robot-assisted laparoscopic transplant-to-native ureteroureterostomy of an intraperitoneal renal allograft. Journal of Pediatric Urology. August 2018.
Contact
Find contact information on Dr. Gong's faculty profile. Emilie Johnson LabImproving outcomes for pediatric patients with both acute and chronic urologic conditions
Improving outcomes for pediatric patients with both acute and chronic urologic conditions
Research Description
Emilie K. Johnson, MD, MPH, is a pediatric urologist with an academic focus in health services and outcomes research. Her research interests and long-term goals are focused on improving outcomes for pediatric patients with both acute and chronic urologic conditions. She has a particular interest in projects with opportunities to develop interventions to improve the quality and safety of care and improve outcomes. Currently, Dr. Johnson is involved in research projects related to differences of sex development and access to neonatal circumcision.
Publications
- Corona LE, Hirsch J, Rosoklija I, Yerkes EB, Johnson EK. Attitudes toward fertility-related care and education of adolescents and young adults with differences of sex development: Informing future care models. J Pediatr Urol. 2022 May 21:S1477-5131(22)00207-8.
- Chan YY, Rosoklija I, Shannon R, Singal A, D'Oro A, Meade P, Gong EM, Lindgren BW, Johnson EK. Urinary Tract Infection After Robot-assisted Laparoscopic Pyeloplasty: Are Urine Cultures and Antibiotics Helpful? Urology. 2021 Feb; 148: 235-242.
- Johnson EK, Jacobson DL, Finlayson C, Yerkes EB, Goetsch AL, Leeth EA, Cheng EY. Proximal Hypospadias-Isolated Genital Condition or Marker of More? Journal of urology. August 2020.
- Sofer L, D'Oro A, Rosoklija I, Leeth EA, Goetsch AL, Moses S, Chen D, Finlayson C, Johnson EK. Impact of Cell-free DNA Screening on Parental Knowledge of Fetal Sex and Disorders of Sex Development. Prenatal diagnosis. July 2020.
- Johnson EK, Maizels M, Meade P, Mitchell MA, Rubio L, Rosoklija I. Development and Outcomes of a Streamlined Outpatient Newborn Circumcision Clinic. Urology Practice. June 2020.
Contact
Find contact information on Dr. Johnson's faculty profile. Bruce Lindgren LabStudying minimally invasive and robotic surgery techniques and outcomes in pediatric urology patients
Studying minimally invasive and robotic surgery techniques and outcomes in pediatric urology patients
Research Description
Dr. Lindgren is active in clinical research in several areas of urology including laparoscopic/robotic surgery and voiding dysfunction. His areas of special interest include hypospadias, undescended testes, hydronephrosis and urinary tract obstruction, and maternal-fetal urology.
Publications
- Shannon R, Jacobson D, Gong E, Lindgren BW. Robot-assisted laparoscopic pyelotomy and ileal ureter substitution: video demonstration. Journal of Pediatric Urology. April 2020.
- Koehne E, Desai S, Lindgren B. Robot-assisted laparoscopic diverticulectomy with ureteral reimplantation. Journal of Pediatric Urology. January 2020.
- Jacobson DL, Shannon R, Johnson EK, Gong EM, Liu DB, Flink CC, Meyer T, Cheng EY, Lindgren BW. Robot-Assisted Laparoscopic Reoperative Repair for Failed Pyeloplasty in Children: An Updated Series. Journal of Urology. May 2019.
Contact
Find contact information on Dr. Lindgren's faculty profile. Dennis Liu LabConducting research to improve care and outcomes for pediatric urology patients
Conducting research to improve care and outcomes for pediatric urology patients
Research Description
Dr. Liu’s research focuses on hypospadias, medical education, and vesicoureteral reflux.
Publications
- D'Oro A, Meyer T, Gong EM, Rosoklija I, Liu DB. Are pressure pop-offs beneficial to the bladder in boys with posterior urethral valves? J Pediatr Urol. 2020 Aug; 16(4): 488.e1-488.e8.
- Malhotra NR, Rosoklija I, Shannon R, D'Oro A, Liu DB. Frequency and Variability of Advice Given to Parents on Care of the Uncircumcised Penis by Pediatric Residents: A Need to Improve Education. Urology. February 2020.
- D'Oro A, Meyer T, Gong EM, Rosoklija I, Liu DB. Are pressure pop-offs beneficial to the bladder in boys with posterior urethral valves? Journal of Pediatric Urology. January 2020.
- Maizels M, Meade P, Rosoklija I, Mitchell M, Liu D. Outcome of circumcision for newborns with penoscrotal web: oblique skin incision followed by penis shaft skin physical therapy shows success. Journal of Pediatric Urology. August 2019.
Contact
Find contact information on Dr. Liu's faculty profile. Max Maizels LabApplying computer enhanced visual learning to enhance traditional teaching methods in pediatric urology
Applying computer enhanced visual learning to enhance traditional teaching methods in pediatric urology
Research Description
Dr. Maizels designs and evaluates computer-enhanced visual learning (CEVL) modules. CEVL is a web-based education program created to enhance traditional teaching methods. The method breaks down surgery into specific sections and steps for trainees. Dr. Maizels’ research aims to make preparations for surgery and interactions between surgeons and operating room staff more effective and efficient.
Publications
- Nixon HC, Stariha J, Farrer J, Wong CA, Maisels M, Toledo P. Resident Competency and Proficiency in Combined Spinal-Epidural Catheter Placement is Improved Using a Computer-Enhanced Visual Learning Program. Obstetric Anesthesia Digest. June 2020.
- Maizels M, Meade P, Rosoklija I, Mitchell M, Liu D. Outcome of circumcision for newborns with penoscrotal web: oblique skin incision followed by penis shaft skin physical therapy shows success. Journal of Pediatric Urology. August 2019.
- Maizels M, Meade P. Computer-enhanced visual learning interactive: judging suitability for newborn circumcision. Journal of Pediatric Urology. April 2019.
Contact
Find contact information on Dr. Maizels' faculty profile. Elizabeth Yerkes LabStudying the treatment and management of genitourinary anomalies, neurogenic bladder and disorders of sex development
Studying the treatment and management of genitourinary anomalies, neurogenic bladder and disorders of sex development
Research Description
Dr. Yerkes is currently investigating neurogenic bladder in pediatric spina bifida patients. She is collaborating with Dr. Earl Cheng and Dr. Robin Bowman to integrate knowledge and input from both Urology and Neurosurgery for a multidisciplinary approach to research.
Publications
- Chan YY, Chu DI, Hirsch J, Kim S, Rosoklija I, Studer A, Brockel MA, Cheng EY, Raval MV, Burjek NE, Rove KO, Yerkes EB. Implementation and sustainability of an enhanced recovery pathway in pediatric bladder reconstruction: Flexibility, commitment, teamwork. J Pediatr Urol. 2021 Sep.
- Yerkes EB, Baum M, Chu DI. Chronic kidney disease and upper tract concerns after congenital and acquired urinary tract abnormalities: considerations for transition of care in teens and young adults. World J Urol. 2021 Apr; 39(4): 1003-1011.
- Yerkes EB, Baum M, Chu DI. Chronic kidney disease and upper tract concerns after congenital and acquired urinary tract abnormalities: considerations for transition of care in teens and young adults. World Journal of Urology. January 2020.
- Szymanski KM, Fuchs M, McLeod D, Rosoklija I, Strine AC, Vanderbrink B, Whittam B, Yerkes E, Gargollo PC. Probability of Bladder Augmentation, Diversion and Clean Intermittent Catheterization in Classic Bladder Exstrophy: A 36-Year, Multi-Institutional, Retrospective Cohort Study. Journal of Urology. December 2019.