Northwestern University Feinberg School of Medicine

Center for Circadian and Sleep Medicine

Clinical Trials

The Center for Circadian and Sleep Medicine is focused on clinical research. Learn more about the trials and participation opportunities via the search results for Northwestern Neurology on clinicaltrials.gov. Below is a selected list of our current active protocols.

Feinberg Clinical Trials

Scientists at the medical school are conducting hundreds of clinical trials daily. Learn more about all our work via the Feinberg Office of Research Clinical Trials page. Search for trials by disease or condition.

Asteria Survey

Please complete this survey if you are interested in participating in the Asteria clinical trial (details below).

Trials
Circadian rhythms and epilepsy
This study is to further understand the link between epilepsy, sleep and circadian rhythms. We propose to characterize sleep-wake and circadian rhythm patterns in patients with epilepsy (PWE). To assess the interactions between circadian function and sleep quality with …
This study is to further understand the link between epilepsy, sleep and circadian rhythms. We propose to characterize sleep-wake and circadian rhythm patterns in patients with epilepsy (PWE). To assess the interactions between circadian function and sleep quality with seizure frequency and timing by data from self- reported sleep and circadian chronotype questionnaires, sleep diaries, seizure type and frequency as reported by the subjects’ primary physician, and objective sleep (actigraphy) and circadian rhythm measures.
Adults (18 years of age and older) with generalized seizures and focal seizures.
Patients are allowed to remain on their usual regimen of antiepileptic medications.

Zee, Phyllis CZee, Phyllis C
STU00201284
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Erlikh, Natanie 1-888-NU-STUDY
MATRICS
The MATRICS Study - This study aims to investigate the effectiveness of different combinations and sequences of evidence-based treatment strategies for people with both Obstructive Sleep Apnea and Insomnia. Participants will be randomly assigned to one of three treatment conditions using a me…
The MATRICS Study - This study aims to investigate the effectiveness of different combinations and sequences of evidence-based treatment strategies for people with both Obstructive Sleep Apnea and Insomnia. Participants will be randomly assigned to one of three treatment conditions using a medical device known as CPAP, or using this device in combination with a behavioral treatment to improve sleep.
Inclusion Criteria:
Males and Females age 18 and older;
Meets criteria for Obstructive Sleep Apnea;
Meets criteria for an Insomnia Disorder; Able to make around 15 in-person visits over 7-9 months.
Exclusion Criteria:
Comorbid medical condition that requires immediate treatment of OSA;
Severe cases of OSA that require immediate treatment;
Psychiatric conditions that may interfere with study protocol or uncontrolled psychiatric conditions that require immediate treatment;
Comorbid sleep disorders that require treatment outside of the study protocol;
Other sleep-related breathing disorder besides OSA;
Excessive daytime sleepiness that requires immediate treatment or presents significant risk;
CPAP use or formal CBT for insomnia within the past 6 months.
Ong, Jason COng, Jason C
NCT01785303 STU00203478
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Yap, Bonnie 312 503 6627
Light in DSWPD
This study is looking at factors that contribute to the timing of sleep. Interested subjects will undergo screening to determine their sleep-wake habits, then will have an eye test and a blood draw. Participation will involve 2 outpatient visits, separated by up to 3 weeks of sleep-w…
This study is looking at factors that contribute to the timing of sleep. Interested subjects will undergo screening to determine their sleep-wake habits, then will have an eye test and a blood draw. Participation will involve 2 outpatient visits, separated by up to 3 weeks of sleep-wake activity monitoring.
Individuals with delayed sleep-wake phase disorder and healthy controls
Abbott, SabraAbbott, Sabra
  • Map it 201 E. Huron St.
    Chicago, IL
STU00203647
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Abbott, Sabra 312 503 3561
Home sleep and circadian phase
Screening includes overnight stay with a full sleep study and morning blood tests. If you qualify full study includes 1 week of wrist actigraphy at home, saliva collectioning at home for one evening, home visit by study staff, and second overnight stay with blood tests …
Screening includes overnight stay with a full sleep study and morning blood tests. If you qualify full study includes 1 week of wrist actigraphy at home, saliva collectioning at home for one evening, home visit by study staff, and second overnight stay with blood tests the next morning.
Age 21-50. African American or Caucasian. Healthy adult.
Knutson, KristenKnutson, Kristen
  • Map it 201 E. Huron St.
    Chicago, IL
NCT01786564 STU00204605
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Brenner-Jedwabnik, Matthew 312 503 4965
Morning Light Treatment
The study is titled “Morning Light Treatment.” We think there may be a relationship between sleep and diabetes, and morning light treatment delivered through a head worn light device could improve glucose metabolism in people with prediabetes.
We are looking for people ages 40-65, who are overweight or obese, do not currently have diabetes, and are in good health. The study involves screening blood tests, at-home apnea test, 5 weeks of wrist actigraphy, a 4 week period where you would wear a light device for one hour in the morning, and 2 overnight laboratory sessions that include saliva, urine, and blood samples. You will be compensated up to $525, $50 for the screening and $95 for each week of participation.
Knutson, KristenKnutson, Kristen
  • Map it 201 E. Huron St.
    Chicago, IL
STU00204710
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For more information on this study please contact us:

Brenner-Jedwabnik, Matthew 312 503 4965