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Northwestern University Feinberg School of Medicine
Disordered Tissue Biomechanics as a Driver of Esophageal Disease
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Biophysiological Modeling Core

PIs: Neelesh Patankar, PhD; Wejun Kou, PhD


The Biophysiologic Modeling Core is a centralized analysis program and database that provides high-level physiological data to be coupled with clinical data through the Biorepository and a mechanism to develop and refine in-silico mathematical models using in-vivo human data.

The core will enable three primary activities:

  • fundamental research of organ/system physiology
  • patient specific analysis and diagnostics, and
  • design and development of next generation diagnostic tools (e.g. manometry).


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