Innovative, collaborative research.

The Department of Neuroscience at Northwestern University Feinberg School of Medicine is devoted to outstanding research and committed to excellence in education. Our faculty participate in teaching medical and graduate students and are proud of their contribution to this important enterprise.

Learn About Us

What We Do

Research

Our research spans the full spectrum of investigation into neural function and dysfunction, bridging the levels of genes, molecules, dendrites, axons, cell types, circuits, systems and behavior.

BROWSE OUR LABORATORIES

Education

In addition to directing their own independent research programs, our faculty are responsible for supervising the research training of postdoctoral fellows and graduate students.

EXPLORE EDUCATION OPPORTUNITIES

Recent Publications

Multipotent bone marrow cell-seeded polymeric composites drive long-term, definitive urinary bladder tissue regeneration.

Bury MI, Fuller NJ, Wang X, Chan YY, Sturm RM, Oh SS, Sofer LA, Arora HC, Sharma TT, Nolan BG, Feng W, Rabizadeh RR, Barac M, Edassery SS, Goedegebuure MM, Wang LW, Ganesh B, Halliday LC, Seniw ME, Edassery SL, Mahmud NB, Hofer MD, McKenna KE, Cheng EY, Ameer GA, Sharma AK.

PNAS Nexus. 2024 Jan 30;3(2):pgae038. doi: 10.1093/pnasnexus/pgae038. eCollection 2024 Feb.

GABAergic regulation of striatal spiny projection neurons depends upon their activity state.

Day M, Belal M, Surmeier WC, Melendez A, Wokosin D, Tkatch T, Clarke VRJ, Surmeier DJ.

PLoS Biol. 2024 Jan 31;22(1):e3002483. doi: 10.1371/journal.pbio.3002483. eCollection 2024 Jan.

Mechanical hyperalgesia and neuropathic pain qualities impart risk for chronic postoperative pain after total knee replacement.

Vigotsky AD, Cong O, Pinto CB, Barroso J, Perez J, Petersen KK, Arendt-Nielsen L, Hardt K, Manning D, Apkarian AV, Branco P.

medRxiv [Preprint]. 2024 Jan 17:2024.01.16.24301372. doi: 10.1101/2024.01.16.24301372.

iPSC-derived models of PACS1 syndrome reveal transcriptional and functional deficits in neuron activity.

Rylaarsdam L, Rakotomamonjy J, Pope E, Guemez-Gamboa A.

Nat Commun. 2024 Jan 27;15(1):827. doi: 10.1038/s41467-024-44989-7.

Bidirectional Regulation of GABAA Reversal Potential in the Adult Brain: Physiological and Pathological Implications.

Kim HR, Martina M.

Life (Basel). 2024 Jan 19;14(1):143. doi: 10.3390/life14010143.

Dopamine across timescales and cell types: Relevance for phenotypes in Parkinson's disease progression.

Seiler JL, Zhuang X, Nelson AB, Lerner TN.

Exp Neurol. 2024 Apr;374:114693. doi: 10.1016/j.expneurol.2024.114693. Epub 2024 Jan 17.

Notch receptor-ligand binding facilitates extracellular vesicle-mediated neuron-to-neuron communication.

Wang YZ, Castillon CCM, Gebis KK, Bartom ET, d'Azzo A, Contractor A, Savas JN.

Cell Rep. 2024 Jan 17;43(2):113680. doi: 10.1016/j.celrep.2024.113680. Online ahead of print.

Top-down control of flight by a non-canonical cortico-amygdala pathway.

Borkar CD, Stelly CE, Fu X, Dorofeikova M, Le QE, Vutukuri R, Vo C, Walker A, Basavanhalli S, Duong A, Bean E, Resendez A, Parker JG, Tasker JG, Fadok JP.

Nature. 2024 Jan;625(7996):743-749. doi: 10.1038/s41586-023-06912-w. Epub 2024 Jan 17.

Neural heterogeneity controls computations in spiking neural networks.

Gast R, Solla SA, Kennedy A.

Proc Natl Acad Sci U S A. 2024 Jan 16;121(3):e2311885121. doi: 10.1073/pnas.2311885121. Epub 2024 Jan 10.

Long-range action of an HDAC inhibitor treats chronic pain in a spared nerve injury rat model.

Centeno MV, Alam MS, Haldar K, Apkarian AV.

bioRxiv [Preprint]. 2023 Dec 14:2023.12.13.571583. doi: 10.1101/2023.12.13.571583.

Basic Science Administration

Our department is supported by the Basic Science Administration group. The team provides assistance related to research and financial administration, professional affairs, facilities and communications.

VISIT BASIC SCIENCE ADMINISTRATION SITE

 

Starzl Academy

Physician-Scientist Training & Resources

We offer a wide range of resources, mentorship opportunities and formal training programs to help our residents and fellows excel as physician-scientists. Explore all of the resources and hear from housestaff who are making research a major part of their career development plans.

Visit the Starzl Academy Site

Follow Neuroscience on