Recent Publications

Intact Mass Profiling Reveals Phospho-Proteoforms of the Catenins (85-110 kDa) Regulated by Actomyosin Contractility.
Huang CF, Su T, Flozak AS, Gottardi CJ, Kelleher NL.
Angew Chem Int Ed Engl. 2025 Oct 29:e18593. doi: 10.1002/anie.202518593. Online ahead of print.
Schlafen 12 modulation and targeting in acute myeloid leukemia.
Guillen Magaña JN, et al. Among authors: platanias lc, bartom et.
Cancer Res Commun. 2025 Oct 29. doi: 10.1158/2767-9764.CRC-25-0283. Online ahead of print.
Accumulation of succinate suppresses de novo purine synthesis through succinylation-mediated control of the mitochondrial folate cycle.
Nengroo MA, et al. Among authors: ben sahra i, mendillo ml.
Mol Cell. 2025 Oct 28:S1097-2765(25)00819-6. doi: 10.1016/j.molcel.2025.10.002. Online ahead of print.
Next-generation protein sequencing and individual ion mass spectrometry enable complementary analysis of interleukin-6.
Skinner KA, Fisher TD, Lee A, Su T, Forte E, Sanchez A, Caldwell MA, Kelleher NL.
Anal Bioanal Chem. 2025 Oct 1. doi: 10.1007/s00216-025-06120-7. Online ahead of print.
Current applications of radiomics in the assessment of tumor microenvironment of hepatocellular carcinoma.
Choi J, Gordon A, Eresen A, Zhang Z, Borhani A, Bagci U, Lewandowski R, Kim DH.
Abdom Radiol (NY). 2025 Oct;50(10):4661-4675. doi: 10.1007/s00261-025-04916-w. Epub 2025 Apr 10.
NKX2-1 drives neuroendocrine transdifferentiation of prostate cancer via epigenetic and 3D chromatin remodeling.
Lu X, et al. Among authors: yu j.
Nat Genet. 2025 Aug;57(8):1966-1980. doi: 10.1038/s41588-025-02265-4. Epub 2025 Jul 21.
Microtopography-induced changes in cell nucleus morphology enhance bone regeneration by modulating the cellular secretome.
Wang X, et al.
Nat Commun. 2025 Jul 11;16(1):6444. doi: 10.1038/s41467-025-60760-y.
The Proteoform Landscape of Tau from the Human Brain.
Xu T, Su T, Soye BJD, Kandi S, Huang CF, Wilkins JT, Castellani RJ, Kafader JO, Patrie SM, Vassar R, Kelleher NL.
J Proteome Res. 2025 Jun 6;24(6):2916-2925. doi: 10.1021/acs.jproteome.5c00139. Epub 2025 May 20.
Proteoform profiling of endogenous single cells from rat hippocampus at scale.
Su P, et al. Among authors: kelleher nl.
Nat Biotechnol. 2025 May 15:10.1038/s41587-025-02669-x. doi: 10.1038/s41587-025-02669-x. Online ahead of print.
Metabolomic and proteomic analyses of renal function after liver transplantation.
Wang X, Grobe N, Franchin B, Levitsky J, Cravedi P, Kotanko P.
Front Transplant. 2025 Apr 29;4:1572852. doi: 10.3389/frtra.2025.1572852. eCollection 2025.