News and Announcements

In a landmark effort to understand how the physical structure of our DNA influences human biology, Northwestern investigators and the 4D Nucleome Project have unveiled the most detailed maps to date of the genome’s three‑dimensional organization across time and space, according to a new study published in Nature.

Northwestern Medicine scientists have uncovered a surprising link between a tiny cellular engine and the way cancer cells build the DNA they need to proliferate, according to a new study published in Molecular Cell.

Distinguished biochemist Svetlana Mojsov, PhD, the Lulu Chow Wang and Robin Chemers Neustein Research Associate Professor at the Rockefeller University, New York, has been named the winner of the annual $250,000 Kimberly Prize in Biochemistry and Molecular Genetics.

Northwestern Medicine scientists have developed a comprehensive atlas of genetic coding sequences in both healthy adult hearts and those with heart failure, as detailed in a recent study published in Circulation.

Northwestern scientists have discovered that the organization of a cell’s genetic material dictates cancer’s ability to adapt, according to a recent study published in the Proceedings of the National Academy of Sciences.

Feng Yue, PhD, the Duane and Susan Burnham Professor of Molecular Medicine in the Department of Biochemistry and Molecular Genetics, has been inducted into the 2025 class of American Institute for Medical and Biological Engineering (AIMBE) College of Fellows. 

Northwestern Medicine investigators have discovered new intracellular mechanisms that help specialized immune cells adapt and respond to disease and acute inflammation, findings that may inform the development of targeted therapies for cancer and tissue injury, according to a recent study published in the Journal of Clinical Investigation.

Ali Shilatifard, PhD, the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, has been elected to the National Academy of Sciences.

Northwestern Medicine investigators have discovered how disruptions in circadian rhythm in our muscles combined with poor diet can contribute to the development of diabetes, according to a recent study published in Proceedings of the National Academy of Sciences.

Circadian rhythms play a role in how quickly damaged muscles heal, according to a Northwestern Medicine study published in Science Advances.

Northwestern Medicine investigators have developed a new avenue to reprogram compromised immune cells to work against tumors, according to a study published in Science Advances.

Northwestern Medicine scientists have uncovered a key pathway controlling tumor growth in B-cell lymphomas, according to a study published in the Journal of Clinical Investigation.

Investigators have developed a catalog of transcription factor binding sites that regulate gene expression across the genome, findings that may improve the understanding of underlying causes of developmental disorders and cancer, according to a recent study.

Investigators from the laboratory of Ali Shilatifard, PhD, have developed a novel technique to precisely and efficiently study gene regulation, which may accelerate the development of new therapeutic strategies, according to a recent study published in Molecular Cell.

A Northwestern Medicine study has detailed the development of a machine learning model to predict DNA methylation status in cell-free DNA by its fragmentation patterns, according to findings published in Nature Communications.