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News & Announcements

Read the latest news from the Bluhm Cardiovascular Institute's Clinical Trials Unit to learn about our recent discoveries, successes, faculty achievements and honors.

  • 07.22.2024

    Proteomic analysis of blood samples from pregnant individuals did not improve risk prediction of hypertensive disorders of pregnancy compared to current methods, underscoring the demand for more accurate prediction tools, according to findings published in JAMA Cardiology.

  • 07.01.2024

    Northwestern Medicine investigators have uncovered how a single protein contributes to heart transplant tolerance in mice, according to a study published in the Proceedings of the National Academy of Sciences.

  • 06.24.2024

    Inflamed heart muscles can mount immune responses even in the absence of immune cells, according to a Northwestern Medicine study published in the Journal of Clinical Investigation.

  • 06.11.2024

    Patients with obstructive hypertrophic cardiomyopathy who received a new drug demonstrated improved oxygen uptake and exercise tolerance, according to a study published in the New England Journal of Medicine.

  • 05.30.2024

    Northwestern Medicine scientists have discovered a way to regenerate damaged heart muscle cells in mice, a development which may provide a new avenue for treating congenital heart defects, according to a study published in the Journal of Clinical Investigation.

  • 05.08.2024

    Semaglutide, sold under brand names Ozempic and Wegovy, can help reduce heart failure symptoms and reduce heart failure hospitalizations in patients with obesity, according to a pair of studies published in The Lancet and The New England Journal of Medicine.

  • 04.23.2024

    Feinberg investigators have been selected to lead a $15 million American Heart Association research initiative studying the role of inflammation in heart disease.

  • 04.15.2024

    Combining multiple heart disease drugs into a single “polypill” can lower bad cholesterol and blood pressure, boost medication adherence, and reduce the risk of cardiovascular disease and death, according to a meta-analysis of recent clinical trials published in Nature Medicine.

  • 02.23.2024

    A multidisciplinary team of investigators have engineered a more accurate model for studying the underlying mechanisms of atrial fibrillation and treatment response, according to findings published in Science Advances.

  • 01.16.2024

    Investigators led by Elizabeth McNally, MD, PhD, the Elizabeth J. Ward Professor of Genetic Medicine and director of the Center for Genetic Medicine, have discovered previously unknown protein interactions in the heart’s atrium that are critical for normal heart function, according to findings published in the Proceedings of the National Academy of Sciences.

  • 12.19.2023

    Two years after the FDA’s approval of semaglutide for chronic weight management, Northwestern Medicine scientists remain at the forefront of investigating the drug’s potential in helping patients who are overweight or have obesity who also have other preexisting health conditions.

  • 12.01.2023

    A common diabetes medication may help some patients with treatment-resistant hypertension slightly lower their high blood pressure and lessen their risk of heart failure events such as stroke, according to an analysis of a clinical trial published in Circulation.

  • 11.27.2023

    Patients with severe aortic stenosis who underwent a minimally invasive aortic valve replacement procedure had similar long-term survival rates compared to patients who underwent traditional surgery, according to a recent study published in The New England Journal of Medicine.

  • 11.17.2023

    For the first time in 10 years, the American Heart Association has updated the model to predict someone’s risk of developing heart disease.

  • 11.13.2023

    Nearly everyone can lower their blood pressure, even people currently on blood pressure-reducing drugs, by lowering their sodium intake, according to a new study published in JAMA.

  • 10.12.2023

    A new Northwestern Medicine study has found obesity before pregnancy is the root cause of future cardiovascular disease, rather than pregnancy complications.

  • 10.11.2023

    A novel cellular pathway regulates DNA damage and structural changes in cardiomyocytes which contributes to the development of cardiac hypertrophy according to a Northwestern Medicine study published in Circulation.

  • 10.02.2023

    The antidiabetic and weight loss drug semaglutide, sold under the brand names Ozempic and Wegovy, can also help patients with heart failure and obesity lose weight while also improving symptoms and increasing exercise capacity, according to a clinical trial published in the New England Journal of Medicine.

  • 09.07.2023

    Investigators have identified more than 60 previously unknown genetic variants associated with resting heart rate that may also contribute to increased risk of cardiovascular disease, according to findings published in Nature Communications.

  • 08.28.2023

    The Coronary Artery Risk Development in Young Adults (CARDIA) study has received a 10-year $11 million grant renewal from the National Heart, Lung, and Blood Institute at the National Institutes of Health.

  • 07.28.2023

    Black residents living in highly segregated neighborhoods have significantly shortened life expectancies, according to a new Northwestern Medicine study.