Treating cancer has become increasingly difficult as cells develop resistance. Northwestern investigators have sought to address this issue on the cellular level through the development of a novel FateMap tool, used to predict the future behavior of cancer cells before they are exposed to cancer-fighting drugs. In this episode, Yogesh Goyal, PhD, discusses his latest research, published in Nature, and how his lab is addressing complex problems through an interdisciplinary approach.
News and Announcements
Read the latest news from Northwestern University Feinberg School of Medicine’s basic science academic departments. The links below take you to articles where you can learn more about our faculty’s latest achievements, awards and honors.
Biochemistry and Molecular Genetics
09.26.2023A multi-institutional team of investigators including Northwestern University scientists has received $45 million to fast-track the development of a first-of-its-kind implant to sense and treat cancer.
09.20.2023Northwestern Medicine investigators have discovered how the PD-1 protein controls essential metabolic processes in tumor cells to promote cancer growth in T-cell non-Hodgkin lymphomas, according to a study published in Nature Cancer.
09.11.2023Northwestern Medicine scientists have developed an engineered probiotic capable of detecting inflammatory bowel disease, according to a study published in the Proceedings of the National Academy of Sciences.
Cell and Developmental Biology
07.19.2023Scientists have created a new synthetic biology approach to follow tumor cells over time, finding meaningful differences in why a cancer cell dies or survives in response to anti-cancer therapies.
07.19.2023 Breakthroughs Podcast
06.29.2023As the field of biomedical research becomes more technology-driven, having access to state-of-the art technology is even more important to accelerate research and discovery.
Microbiology-Immunology
- 09.11.2023
Northwestern Medicine scientists have developed an engineered probiotic capable of detecting inflammatory bowel disease, according to a study published in the Proceedings of the National Academy of Sciences.
08.17.2023Northwestern Medicine scientists have discovered how HIV hijacks intracellular processes to proliferate and contribute to neurodegeneration, according to a new study published in Nature Communications.
06.06.2023Northwestern Medicine investigators have developed a novel nanoparticle treatment for glioblastoma, according to a study published in Nature Communications.
Pharmacology
09.25.2023Northwestern Medicine investigators have uncovered new mechanisms by which iron deficiency inhibits cell growth and proliferation in eukaryotic cells, findings that could improve the understanding of cancer growth and the development of targeted cancer therapies.
09.14.2023Northwestern Medicine investigators have identified how a calcium channel in the nervous system contributes to brain inflammation, according to a study published in Nature Communications.
08.21.2023A new Northwestern Medicine study has discovered a novel therapeutic target and therapeutic agents for older patients with acute respiratory distress syndrome, according to recent findings published in Science Translational Medicine.
Neuroscience
08.16.2023Today, more than 50 million adults in the U.S. suffer from chronic pain — pain lasting longer than three months — and is the most common reason why people seek medical attention, according to the Centers for Disease Control and Prevention (CDC).
08.10.2023Northwestern investigators have discovered the mechanisms by which PCDH12, a protein critical to cell adhesion, also contributes to neuron production and neuronal migration during brain development, according to a recent study published in Cell Reports. Loss of PCDH12 function is associated with severe neurodevelopmental disorders, such as microcephaly, infantile epilepsy and autism. The findings of the study shed light on mechanisms of brain cortex development and advance our understanding of pathogenic mechanisms of PCDH12-related neurodevelopmental disorders, ultimately aiding in the identification of potential therapeutic targets.
08.03.2023A new Northwestern University-led study published in Nature Neuroscience has discovered that dopamine neurons are more diverse than previously thought, opening new research directions for further understanding and potentially even treating Parkinson’s disease.