Division of Reproductive Biology Research
Chakravarti Laboratory
Publications
Seo, S-B., McNamara, P., Heo, S., Turner, A., Lane, W.S., and Chakravarti, D. Regulation of histone acetylation and transcription by INHAT, a novel human cellular complex containing the Set oncoprotein. Cell 104: 119-130, 2001.
McNamara, P., Seo, S-B, Rudic, R.D., Sehgal, A., Chakravarti, D., and FitzGerald, G.A. Regulation of CLOCK and MOP4 by nuclear hormone receptors in the vasculature: A humoral mechanism to reset a peripheral clock. Cell 105, 877-889, 2001.
Li, F, Macfarlan, T., Pittman, R.N., and Chakravarti, D. Ataxin-3 is a histone binding protein with two independent transcriptional corepressor activities, J. Biol. Chem. 277: 45004-45012, 2002.
Hong, R., and Chakravarti, D. The human proliferating cell nuclear antigen regulates transcriptional coactivator p300 activity and promotes transcriptional repression. J. Biol. Chem. 278: 44505-44513, 2003.
Chakravarti D. and Hong, R. SET-ting the stage for life and death. Cell 112: 589-591, 2003.
Kutney S.N., Hong, R., Macfarlan, T., and Chakravarti, D. A signaling role of histone-binding proteins and INHAT subunits pp32 and Set/TAF-I beta in chromatin hypoacetylation and transcriptional repression. J.Biol. Chem. 279: 30850-30855, 2004.
Hong, R., Macfarlan, T., Kutney, S.N., Seo, S.B., Mukai, Y., Yelin F., Pasternack, G.R. and Chakravarti, D. The identification of phosphorylation sites of pp32 and biochemical purification of a Cellular pp32-kinase. Biochemistry. 43, 10157-10165, 2004.
Macfarlan, T., Kutney, S., Altman, B., Montross, R., Yu, J., and Chakravarti, D. Human THAP7 is a chromatin-associated, histone tail binding protein that represses transcription via recruitment of HDAC3 and nuclear receptor corepressor. J.Biol. Chem. 280, 7346-7358, 2005
Macfarlan, T., Parker, J.B., Nagata, K., and Chakravarti, D. Thanatos-associated protein 7 associates with template activating factor –Ibeta and inhibits histone acetylation to repress transcription. Mol.Endo (in press) Feb, 2006.
