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Breakthroughs, the newsletter of the Feinberg School of Medicine Research Office

SEPTEMBER 2025 NEWSLETTER

The newsletter of the Feinberg School of Medicine Research Office

Feinberg Scientists Reveal Hidden Dynamics of the Cell’s Smallest Structures

Scientists at Feinberg are reshaping scientific understanding of the cell’s tiniest components—structures once thought to be static, now revealed to be dynamic engines of cellular life. As they probe the inner workings of cells, they are not only expanding understanding of cellular processes but also paving the way for novel therapies and diagnostics. 

Read the Feature

Celebrating Scientific Discovery and Collaboration at Research Day 2025

Feinberg students, staff, trainees and faculty celebrated scientific discoveries and presented their research posters and abstracts at Feinberg’s 19th annual Lewis Landsberg Research Day on Thursday, Sept. 11.

Read about Research Day

Nation’s First MIRAVA Polyscope Comes to Center for Advanced Microscopy

Feinberg investigators now have access to one of the most advanced super-resolution imaging systems in the world, thanks to the installation of the MIRAVA Polyscope at the Center for Advanced Microscopy (CAM) at Northwestern University. This groundbreaking instrument—developed by Nobel Laureate Stefan Hell—is the first of its kind in the United States and among the first fully operational systems worldwide.

Read the story

Faculty Profile

Investigating the Molecular Mechanisms Underlying Epithelial Cell Function

Brian Mitchell, PhD, is an associate professor of Cell and Developmental Biology. His laboratory aims to understand the integration of cell signaling and cytoskeletal dynamics on diverse developmental processes including centriole amplification, cell migration and cell polarity.

Read more about his research

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Student Profile

Understanding How Social Drivers Affect Health Through Epigenetics

Mindy Szeto is a PhD student in the Health Sciences Integrated Program (HSIP) at Feinberg in the Health and Biomedical Informatics (HBMI) track. Szeto is currently analyzing early life social and environmental exposures and epigenetic mediators contributing to cardiovascular disease risk.

Read more about her research

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Staff Profile

Supporting Sinus Research

James Norton is the research laboratory manager in the Division of Allergy and Immunology at Feinberg. In his roles, Norton has supported the research enterprise at Feinberg for more than 20 years.

Read more about his research

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Campus Events

Tue
Sep 16

Lunch & Learn Series: Lauren Bonner, PhD - "Hyperbaric oxygen therapy for ulcerative colitis"

Chicago - 12:00 PM - 1:00 PM

Tue
Sep 16

SQLIFTS Lecture Series - Preetish Kadur Lakshminarasimha Murthy, PhD/UIC (Speaker) - "Region-specific reprogramming of human airway stem cells"

Chicago - 12:00 PM - 1:00 PM

Wed
Sep 17

Office of the Ombudsperson Tabling Event at Feinberg School of Medicine

Chicago - 9:30 AM - 2:00 PM

Thu
Sep 18

Why Medical Humanities and Bioethics? Five-minute faculty takes on the field and how we got here

Chicago - 12:00 PM - 12:45 PM

Research in the News

US News & World Report, Sept 2
Heart Failure Strikes Black Americans Almost 14 Years Earlier Than White Americans
Xiaoning Huang, PhD, was featured.

US News & World Report, Sept 2
'Reborn Again': Blind Bride-To-Be Thriving After Triple-Organ Transplant
Benjamin Bryner, MD, Jonathan Rich, MD, and Juan Caicedo-Ramirez, MD were featured.

Chicago Sun-Times, August 25
Northwestern study finds kids in ‘low opportunity’ areas are up to 20 times more likely to be shot
Anne Stey, MD, was featured.

Check out More Media Coverage

NUCATS Corner

Registration Open for NUCATS Mentor Development Series

Registration for the NUCATS Mentor Development Series is now open in MyHR Learn. Please see important links below. This series is reserved for faculty only. All workshops are held in person, limited to 42 participants, and spots are available on a first-come, first-served basis. If a workshop is at capacity, you will be added to a waitlist within the MyHR Learn system. 

Please make sure to keep an eye out for confirmation emails from MyHR Learn and accept the associated calendar invites. The NUCATS Mentor Training Certificate Program fulfills the NIH mentoring requirements. 

Please email Morgan Barrowman with any questions.

Learn More about The Series

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Breakthroughs Podcast Rewind

The Role of Dopamine in Habit Formation and Compulsive Behavior with Talia Lerner, PhD

In this episode, Lerner discusses how habits both good and bad are formed in the brain, and the role habits may play in diseases of the brain. Her research may change the overall understanding of how habits are formed and could be broken.

Listen to the podcast episode

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New Faculty

Fumiaki Ito, PhD, joined Feinberg as assistant professor of Microbiology-Immunology in September 2025. Ito studies the molecular mechanisms of viral replication, antiviral immunity, and virus–host interactions involved in various DNA/RNA viruses. Their work uses cryo-electron microscopy (cryo-EM) and other biophysical/biochemical techniques to understand complex and dynamic processes by which viruses manipulate and hijack host cells, as well as how the host immune system responds to infection. Prior to coming to Northwestern, Ito was a postdoctoral fellow at UCLA.
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Sponsored Research

AI Driven End-to-End 4D flow MRI Pipeline for Hemodynamic Assessment in BAV Disease

PI: Michael Markl, PhD, vice chair for research in the Department of Radiology and Lester B. and Frances T. Knight Professor of Cardiac Imaging 

Sponsor: National Heart Lung and Blood Institute 

Read more about this project

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Galter Library

Preparing for the NIH Common Forms: Updated Timeline and Previews Available in SciENcv

In July 2024, the NIH announced a requirement for all grant proposals to use federal Common Forms for the NIH biosketch and for the Other Support document, and that these documents must be prepared using the NIH platform SciENcv. To support this transition, NIH launched PREVIEW versions of the Common Forms in SciENcv on September 10, 2025. 

Learn More About this Change

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ENVIRONMENTAL SUSTAINABILITY & PUBLIC HEALTH

Strategic Initiatives of the University

One of Northwestern’s six research and innovation priorities is to lead in sustainability, broadly defined. Supported by the Office of the Provost, Jennifer Dunn, PhD is leading an initiative to understand current efforts in this space and opportunities to expand the scope of sustainability research and education at Northwestern, including work that leads to improved land, air, and water quality and public health. This initiative aims to find and encourage points of connection across Northwestern’s schools and campuses in order to provide easy entry points for alumni, donors, and others who are interested in funding these endeavors. 

To inform this initiative, Dunn has held a series of conversations with Feinberg faculty, including faculty members from IPHAM, Medical Social Sciences, Preventive Medicine, the Institute for Artificial Intelligence in Medicine and NUCATS. 

If your work intersects with environmental sustainability or if you are interested in learning more, please email StrategicInitiatives@northwestern.edu 

Learn More About Sustainability

High Impact Research

Nassar AH, Kim C, Adeyelu T, Bou Farhat E, Abushukair H, Rakaee M, Matteson K, Lau SF, Takabe Y, Ocejo A, Ardeshir-Larijani F, Leal T, Ramalingam S, Alam S, Gray JE, Hicks J, Kaldas D, Baena J, Berjaga MZ, Nana FA, Grohe C, Leuders H, Citarella F, Cortellini A, Mingo EC, Pancirer D, Das M, Ellis-Caleo TJ, Cheung JM, Lin JJ, Watson AS, Camidge DR, Sridhar A, Parikh K, Crowley F, Marron TU, Aggarwal V, Ahmed M, Sankar K, Kawtharany H, Zhang J, Owen DH, Li M, Nagasaka M, Pinato DJ, Awosika N, Alhamad K, Puri S, Zaman U, Gupta DM, Lau C, Khan H, Liauw J, Velazquez AI, Brown T, Moliner L, Mosteiro M, Rocha P, Evans M, Vanderwalde A, Elliott A, Nieva J, Lopes G, Ma PC, Borghaei H, Lee M, Young L, Aljumaily R, Mirza H, Kwiatkowski DJ, Herbst RS, Flavell RA, Naqash AR, Chiang AC. Integrated molecular and clinical characterization of pulmonary large cell neuroendocrine carcinoma. Nature Communications. Aug 2025; 16(1):7717-7717.

Nelson RS, Grossman MG, Klug ZM, Calamari M, Donayre A, Cybulski T, Schooley J, Griffith GJ, Corcos DM, Wright DE, Wallace JC, Yang DS, Wright JA, Rogers JA, Lee SP, Ghaffari R, Aranyosi AJ, Jain M. Remote analysis and management of sweat biomarkers using a wearable microfluidic sticker in adult cystic fibrosis patients. Proceedings of the National Academy of Sciences of the United States of America. Aug 2025; 122(33):e2506137122-e2506137122.

Ouyang W, Chen Y, Tan T, Song Y, Dong T, Yu X, Lee KE, Zhou X, Tetz Z, Go S, Zeng X, Shao L, Quan C, Zhao T, Tian Y, Kurabayashi K, Jin H, Ma J, Qin J, Williams B, Li Q, Zhu GD, Alam HB, Stringer KA, Li Y, Ma J. A citrullinated histone H3 monoclonal antibody for immune modulation in sepsisNature Communications. Aug 2025; 16(1):7435-7435.

Richardson RAKHong SS, Byrne JA, Stoeger TAmaral LANThe entities enabling scientific fraud at scale are large, resilient, and growing rapidlyProceedings of the National Academy of Sciences of the United States of America. Aug 2025; 122(32):e2420092122-e2420092122.

Review More Publications

Featured Core

Outcomes Measurement and Survey Core

The mission of this core facility is to provide consultation and support for research that involves collecting, analyzing or interpreting self-, proxy-, and observer-report data in culturally diverse populations across the lifespan. 

Key Services

Research Design Consultation Services

  • Assistance with development of new protocols including research objectives, endpoints, and hypotheses
  • Measure selection and implementation (e.g. mode of administration, assessment platform)
  • Survey development
  • Sampling and recruitment strategies utilizing practices to support health equity in research
  • Analysis methods

Programming & Analysis Services

  • Digital patient-reported outcome administration tools
  • Scoring algorithms
  • Psychometric and statistical analysis and interpretation

Research Operations Services

  • Facilitation of translations of measures and surveys
  • Qualitative methods (e.g., focus groups, cognitive interviewing)

Learn more about the core

Funding Opportunities

Search Funding Opportunitities

NIH News

NIH Launches Initiative to Modernize and Strengthen Biosafety Oversight

As the world’s largest public funder of biomedical research, NIH is committed to ensuring that gold-standard science is conducted under gold-standard biosafety conditions. Today, NIH is launching its Biosafety Modernization Initiative – a comprehensive effort to modernize and strengthen biosafety policies, practices, and oversight to keep pace with the evolving risks posed by today’s rapidly advancing science and technology.

In the coming months, NIH will work closely with the research community and stakeholders to create the biosafety framework of the 21st century. First, NIH will revamp biosafety oversight to address potential risks beyond recombinant or synthetic nucleic acid technologies. At the same time, the widespread use of certain low-risk recombinant technologies may no longer warrant the oversight once deemed necessary, allowing us to reduce red tape for some research.

Second, NIH will strengthen our partnerships with institutional oversight bodies to empower Institutional Biosafety Committees (IBC), reinforcing their position as the front lines of biosafety oversight. This will also provide an opportunity for institutional leadership to reassess whether their IBCs are receiving support and resources equal to other institutional committees, such as those who review human subjects research and the care and use of animals.

More NIH News

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Breakthroughs, the newsletter of the Feinberg School of Medicine Research Office